Cognitive Postural Training for Hemineglect Patient After Stroke (CPT)

September 9, 2026 updated by: Alaa Elbaroudy, Ahram Canadian University

EFFECT OF COGNITIVE POSTURAL TRAINING ON POSTURAL STABILITY IN HEMISPATIAL NEGELCT PATIENTS POST STROKE

This randomized controlled trial investigates the effect of Cognitive Postural Training (CPT) on postural stability and cognitive function in patients with hemispatial neglect following stroke. Participants will be randomly assigned to receive either Cognitive Postural Training combined with conventional balance training or conventional balance training alone. Training will be provided three times per week for four weeks. The effects of the intervention on cognitive function, hemispatial neglect, postural stability, balance, and functional independence will be evaluated.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

42

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Egypt
      • Giza, Egypt
        • The out patient clinic Faculty of physicaltherapy Cairo university
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Patients from both genders with hemispatial neglect due to first ever right cerebral hemisphere stroke (ischemic or hemorrhagic).
  • Age of participants ranged from 45 to 65 years.
  • Mild to moderate degree of unilateral spatial neglect according to Catherine Bergego scale.(Appendix VI)
  • The duration of the stroke was at least six months.
  • Body mass index ranged from 18.5 - 30 Kg/m2.
  • Montreal cognitive assessment score more than 21 (Nasreddine, et al., 2005).
  • Mini mental state examination score between 20 and 24 (Li, et al., 2016).
  • Grade of spasticity less than two according to Modified Ashworth Scale (Harb and kishner 2022).
  • Berg balance scale score less than 45 (Miranda-Cantellops, et al., 2022).
  • Muscle power of lower limbs 3 or more

Exclusion Criteria:

  • 21) Other brain injuries/illnesses, psychiatric, sever cognitive impairment, severe sensory or proprioceptive loss.

    22) Other causes of cognitive dysfunction. 23) Severe apraxia, severe aphasia. 24) Drugs that affect balance or cognition 25) Ankle disorders (e.g.sprain), vestibular disorder 26) ophthalmic disorders, homonymous hemianopsia 27) Progressive neurological disease (e.g., dementia)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Cognitive postural training group
Other: Cognitive postural training
CPT consisted of simultaneous performance of cognitive tasks and postural control activities to challenge cognitive-motor integration and postural stability. Cognitive tasks included verbal fluency (e.g., naming animals), mental sequencing (e.g., reciting the months of the year in reverse order), and route-description tasks. Training was progressively performed in different postural positions, including supine, sitting, sit-to-stand, and standing, according to the participant's abilities and level of postural control.
Other: Conventional physical therapy program
conventional balance training focuses on improving postural control, balance, and functional mobility. Training included static and dynamic balance exercises performed in different postural positions, including sitting, sit-to-stand, and standing. Exercises were progressed according to the participant's functional ability and balance performance and included weight-shifting activities, maintaining and changing the base of support, and functional balance activities.
Active Comparator: Conventional physical therapy program group
Other: Conventional physical therapy program
conventional balance training focuses on improving postural control, balance, and functional mobility. Training included static and dynamic balance exercises performed in different postural positions, including sitting, sit-to-stand, and standing. Exercises were progressed according to the participant's functional ability and balance performance and included weight-shifting activities, maintaining and changing the base of support, and functional balance activities.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Overall Stability Index (OSI) - Biodex Balance System
Time Frame: Once at enrollment once at the end of treatment that will last 4 weeks
Once at enrollment once at the end of treatment that will last 4 weeks
Psotural stability- Berg Balance Score
Time Frame: Once at enrollment once at end of treatment that will last for 4 weeks
Once at enrollment once at end of treatment that will last for 4 weeks

Secondary Outcome Measures

Outcome Measure
Time Frame
Cognitive Function - Montreal Cognitive Assessment (MoCA)
Time Frame: Once at enrollment once at end of treatment that will last for 4 weeks
Once at enrollment once at end of treatment that will last for 4 weeks
Global Cognitive Function - Mini-Mental State Examination (MMSE)
Time Frame: Once at enrollment once at end of treatment that will last for 4 weeks
Once at enrollment once at end of treatment that will last for 4 weeks
Hemispatial Neglect - Star Cancellation Test
Time Frame: Once at enrollment once at the end of treatment that will last 4 weeks
Once at enrollment once at the end of treatment that will last 4 weeks
Hemispatial Neglect - Catherine Bergego Scale (CBS)
Time Frame: Once at enrollment once at the end of treatment that will last 4 weeks
Once at enrollment once at the end of treatment that will last 4 weeks
Functional Independence - Barthel Index (BI)
Time Frame: Once at enrollment once at the end of treatment that will last 4 weeks
Once at enrollment once at the end of treatment that will last 4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ahram Canadian University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

September 15, 2026

Primary Completion (Estimated)

October 1, 2026

Study Completion (Estimated)

November 1, 2026

Study Registration Dates

First Submitted

September 9, 2026

First Submitted That Met QC Criteria

September 9, 2026

First Posted (Actual)

September 14, 2026

Study Record Updates

Last Update Posted (Actual)

September 14, 2026

Last Update Submitted That Met QC Criteria

September 9, 2026

Last Verified

September 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • P.T.REC/012/005787 (Other Identifier: Cairo university)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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