Clinical Trials on Demyelination; Corpus Callosum

Total 4340 results

University of Illinois at Chicago

Completed

Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis

Multiple Sclerosis

United States
University of Maryland, Baltimore
Baltimore VA Medical Center

Completed

Physical Telerehabilitation in Veterans With Multiple Sclerosis

Multiple Sclerosis

United States
Genentech, Inc.
Poseida Therapeutics, Inc., a member of the Roche Group

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, and Pharmacodynamics of P-CD19CD20-ALLO1 in Participants With Multiple Sclerosis

Multiple Sclerosis

United States
Karolinska Institutet

Completed

Evaluation of a Self-management Program to Prevent Falls in People With Multiple Sclerosis (Fewer Falls)

Multiple Sclerosis

Sweden
Research Center for Clinical Neuroimmunology and...

Withdrawn

Development of Digital Biomarkers in Multiple Sclerosis: Validation Study 2 (DreaMS_VS2)

Multiple Sclerosis

United States, Austria
Celestra Health Systems
Brigham and Women's Hospital; The Ottawa Hospital; Barts & The London NHS Trust; University of Ottawa

Active, not recruiting

A Novel Wearable Digital Biomarker for Detecting Changes in Multiple Sclerosis (MS) Condition

Multiple Sclerosis

United States, Canada, United Kingdom
Immunic AG

Active, not recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis (ENSURE-1)

Multiple Sclerosis

Jordan, India, Bulgaria, United States, Poland, Montenegro, Lebanon, Georgia, Mexico, Ukraine, Germany, Albania, Algeria, Lithuania, Moldova, North Macedonia
Clene Nanomedicine
University of Texas, Southwestern Medical Center at Dallas

Temporarily not available

Intermediate Expanded Access Protocol CNMAu8.EAP03

Multiple Sclerosis

United States
Novartis Pharmaceuticals

Completed

Survey Among Healthcare Professionals and MS Patients to Assess Their Understanding of RMP Materials

Multiple Sclerosis

Switzerland
University of Alabama at Birmingham
National Multiple Sclerosis Society

Active, not recruiting

Project BIPAMS: Behavioral Intervention for Physical Activity in Multiple Sclerosis (BIPAMS)

Multiple Sclerosis

United States
SYSNAV

Terminated

Prospective Longitudinal Monocentric Study to Evaluate the Syde® Digital Endpoint in Patients With Multiple Sclerosis (NHS-MS-EGYPT)

Multiple Sclerosis

Egypt
Genzyme, a Sanofi Company

Terminated

A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMT (LemKids)

Multiple Sclerosis

Italy, Russia, Austria, France, Poland, Turkey (Türkiye), United Kingdom
Brigham and Women's Hospital
Genentech, Inc.; Boston Medical Center

Completed

Ocrelizumab Access by Socio-Economic Status

Multiple Sclerosis

United States
Hoffmann-La Roche

Completed

This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)

Multiple Sclerosis

Canada, Spain, United Kingdom, Belgium, Croatia, Mexico, Netherlands, Portugal, Slovakia, Norway, Estonia, Brazil, Denmark, Ireland, Czechia, Poland, France, Italy, Argentina, Slovenia, Sweden, Hungary, Finland, Bulgaria, Turkey (Türkiye), Kuwa...
Kessler Foundation
Consortium of Multiple Sclerosis Centers

Completed

Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS) (PACE-MS)

Multiple Sclerosis

United States
Brigham and Women's Hospital
Genzyme, a Sanofi Company

Withdrawn

Effect of Alemtuzumab on Microglial Activation Positron Emission Tomography (PET) in Multiple Sclerosis

Multiple Sclerosis

United States
Biogen

Active, not recruiting

A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)

Multiple Sclerosis

United States
Washington University School of Medicine
University of Colorado, Denver; National Institute of Allergy and Infectious... and other collaborators

Completed

SPINCOMS Biomarker Study (SPINCOMS)

Multiple Sclerosis

United States
Biogen

Terminated

Fampridine Pregnancy Exposure Registry

Multiple Sclerosis | Pregnancy

France
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...
Fondazione Don Carlo Gnocchi Onlus; Istituto Auxologico Italiano

Recruiting

Home Rehabilitation As Continuity of Care in MS (HoReConCareMS)

Multiple Sclerosis

Italy
University of Illinois at Chicago

Recruiting

Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device (MSGH)

Multiple Sclerosis

United States
Fondazione Don Carlo Gnocchi Onlus
Fondazione Italiana Sclerosi Multipla; Ente Ospedaliero Ospedali Galliera

Recruiting

Effect of High Intensity Training on Motor and Cognitive Functions (FAST)

Multiple Sclerosis

Italy
Novartis Pharmaceuticals

Recruiting

Kesimpta Pregnancy and Infant Safety Study Using Real World Data

Multiple Sclerosis

Switzerland
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Impact of Annual Versus Biannual Infusions of Ocrelizumab in Patients With Active MS,After 2 Years of Initial Treatment, on Freedom From Radiological Disease Activity at Two Years: a Multicenter Randomized Controlled Non-inferiority Trial (WINDOCRE)

Multiple Sclerosis

France
Yale University
Roche-Genentech

Recruiting

Identifying and Characterizing Preclinical MS (DREAM)

Multiple Sclerosis

United States
EDMUS Foundation

Recruiting

OFSEP Very High Definition Cohort (VHD cohort)

Multiple Sclerosis

France
Queen Margaret University

Recruiting

The Effects of FES in a Variety of Walking Conditions in People With MS

Multiple Sclerosis

United Kingdom
University of Texas Southwestern Medical Center
EMD Serono

Active, not recruiting

Cladribine Tablets After Treatment With Natalizumab (CLADRINA)

Multiple Sclerosis

United States
NYU Langone Health
National Multiple Sclerosis Society

Completed

Cognitive Markers in Prodromal MS

Multiple Sclerosis

United States
University Medical Center Groningen

Completed

TENS in Persons With MS

Multiple Sclerosis

Netherlands
Novartis Pharmaceuticals

Completed

Effectiveness of Ofatumumab in Real-world Practice

Multiple Sclerosis

United States
The University of Texas at Dallas
Texas Institute for Neurological Disorders

Withdrawn

Assessing the Cognitive Benefits of Ozanimod and Their Brain-Biomarkers in MS

Multiple Sclerosis

United States
GroundWorks DanceTheater

Completed

Outcomes of Group Dance and Movement Training in Ambulatory MS Patients

Multiple Sclerosis

United States
Sanofi

Completed

Study of the Tolerability and Pharmacokinetics of Oral Doses of SAR442168 With a Food Effect Investigation in Healthy Adult Participants

Multiple Sclerosis

United States
Shepherd Center, Atlanta GA
Genzyme, a Sanofi Company; Can Do Multiple Sclerosis

Completed

Pilot Study Evaluating Functional and Wellness Outcomes of the Shepherd CAN DO MS Program

Multiple Sclerosis

United States
Centre Hospitalier Universitaire de Nice

Completed

Silent Progression Activity Monitoring - SPAM Study (SPAM)

Multiple Sclerosis

France
Oregon Health and Science University
Portland VA Medical Center

Completed

A Randomized Controlled Trial of a Multicomponent Walking Aid Program for People With MS (ADSTEP)

Multiple Sclerosis

United States
Pipeline Therapeutics, Inc.

Completed

Phase I Study Evaluating Safety and Tolerability of Escalating Single and Multiple Doses of of PIPE-307 and Food Effect in Healthy Volunteers

Multiple Sclerosis

Australia
University Hospital, Strasbourg, France

Unknown

Retrospective Study on Registry Data to Evaluate the Impact of Ocrelizumab Used in Routine Care in Patients With RRMS (SEP-RR)

Multiple Sclerosis

France
Biogen

Completed

Quantitative Magnetic Resonance Imaging (MRI) Sub-Study of MS PATHS

Multiple Sclerosis

United States, Germany
The Leeds Teaching Hospitals NHS Trust

Unknown

Preventing Job Loss Using Acceptance and Commitment Therapy in Vocational Rehabilitation (MS-Proactive)

Multiple Sclerosis

United Kingdom
Hasselt University

Completed

Walk With Me: a Mobile Application to Improve Walking in Persons With MS

Multiple Sclerosis

Belgium
NYU Langone Health
Stony Brook University

Completed

Pilot Study of Transcranial Direct Current Stimulation (tDCS)

Multiple Sclerosis

United States
VA Office of Research and Development
Memphis VA Medical Center

Completed

Integrating Caregiver Support Into MS Care

Multiple Sclerosis

United States
Biogen

Completed

An Observational Study to Collect Information on Safety and to Document the Drug Utilization of Fampyra (BIIB041) When Used In Routine Medical Practice (LIBERATE)

Multiple Sclerosis

France, Spain, Germany, Netherlands, Argentina, Czechia, Israel, Portugal, United Arab Emirates, Canada, Norway, Lebanon, Ireland
University Hospital, Basel, Switzerland

Completed

Feasibility and Reliability of Multimodal Evoked Potentials (EP-B)

Multiple Sclerosis

Switzerland
University of North Carolina, Chapel Hill

Completed

Characterization of Interferon Beta -1b-Induced Tolerizing Effect in Dendritic Cells

Multiple Sclerosis

United States
Biogen

Completed

Single-Dose Study of a New Formulation of BIIB061

Multiple Sclerosis

United States
Biogen

Completed

Study to Evaluate the Pharmacokinetic Profiles of BIIB017 (Peginterferon Beta-1a) and Rebif® (Interferon Beta-1a) in Healthy Volunteers

Multiple Sclerosis

United States
Sanofi

Completed

A Study to Evaluate the Pharmacokinetic Profiles of Single 14 mg Teriflunomide Tablet in Healthy Chinese Volunteers

Multiple Sclerosis

China

Clinical Trials on Demyelination; Corpus Callosum

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