Clinical Trials on NASH/MASH

Total 764 results

Aligos Therapeutics

Recruiting

ALG-055009 in Non-cirrhotic Adults With MASH (HERALD) (HERALD)

Nonalcoholic Steatohepatitis | NASH | MASH | Metabolic Dysfunction-Associated Steatohepatitis

United States
Akero Therapeutics, Inc

Recruiting

A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NASH/MASH | NAFLD/MASLD

United States, Canada, Puerto Rico, Australia, India
Corcept Therapeutics

Recruiting

A Phase 2b, Study Evaluating Miricorilant in Adult Patients With Nonalcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis (MONARCH)

Nonalcoholic Steatohepatitis (NASH) | Metabolic Dysfunction-associated Steatohepatitis (MASH)

United States, Puerto Rico
Akero Therapeutics, Inc

Recruiting

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NASH With Fibrosis | MASH With Fibrosis

United States, Canada, Puerto Rico, Australia, India, France, Italy, Poland, Spain
Regeneron Pharmaceuticals

Recruiting

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Non-Alcoholic Steatohepatitis (NASH) in Adult Participants at Increased Genetic Risk for This Condition (NASHGEN-2)

Non-alcoholic Steatohepatitis (NASH) | Metabolic Dysfunction Associated Steatohepatitis (MASH)

United States, Korea, Republic of, Puerto Rico, Japan
Enanta Pharmaceuticals, Inc

Completed

Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers.

NASH

United States
89bio, Inc.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
89bio, Inc.

Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

United States
Enanta Pharmaceuticals, Inc

Completed

A Study of EDP-305 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers

NASH

United States, Czechia, Slovakia
Gannex Pharma Co., Ltd.

Not yet recruiting

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Healthy Subjects

NASH
Galmed Pharmaceuticals Ltd
Quotient Sciences

Completed

An Open-Label, Two-Part Study Designed to Assess the Absolute Bioavailability and Mass Balance of Aramchol

NASH

United Kingdom
Milton S. Hershey Medical Center

Recruiting

Feasibility, Safety and Acceptability of a Mobile Health Delivered Exercise Training Program in Patients With Nonalcoholic Steatohepatitis

Exercise | NASH - Nonalcoholic Steatohepatitis | NASH | Liver

United States
Ziauddin University
Nabiqasim Industries (Pvt) Ltd

Completed

Misoprostol for NASH

NASH

Pakistan
Visirna Therapeutics HK Limited

Not yet recruiting

A Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of VSA006 in Chinese NASH Patients

Nash
Hadassah Medical Organization

Withdrawn

Natural Soybean-derived Femarelle ®for Patients With Non Alcoholic Fatty Liver Disease

Nash

Israel
Milton S. Hershey Medical Center

Not yet recruiting

Digital Therapeutic Lifestyle Intervention Program for Patients With MASLD (ENLIGHTEN)

Liver Diseases | NASH - Nonalcoholic Steatohepatitis | NASH
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis) (FRAMES)

Fibrosis | Cirrhosis | NAFLD | NASH - Nonalcoholic Steatohepatitis | NASH
Spectrum Pharmaceuticals, Inc

Completed

Safety, Tolerability and Systemic Absorption of Menadione Topical Lotion for Epidermal-Growth-Factor-Receptor (EGFR) Inhibitor-Associated Rash

EGFR Inhibitor-associated Rash

United States, Canada
TWi Biotechnology, Inc.

Completed

Prophylactic Treatment of Skin Rash Associated With EGFR Inhibitor Therapy

EGFR Inhibitor-Induced Skin Rash

Taiwan
Rabin Medical Center

Completed

Evaluating Preventive Therapy With Oint Threolone, Synthomycine or Aqua Cream, for EGFR'I Induced Acneiform Rash (EGFR'I)

Acneiform Rash

Israel
Chipscreen Biosciences, Ltd.

Recruiting

A Phase II Clinical Trial of Chiglitazar for NASH

NASH

China
George Washington University
University of California, San Diego; World Bank; University of Malawi

Active, not recruiting

Schooling, Income, and HIV Risk in Malawi (SIHR)

HIV | Schooling | Conditional Cash Transfers | Unconditional Cash Transfers

Malawi
Viking Therapeutics, Inc.

Recruiting

Phase 1 Study to Evaluate the Safety and Tolerability of VK2735

Weight Loss | NASH

Australia
University of Oxford
Assistance Publique - Hôpitaux de Paris; University of Nottingham; Novartis; Pf... and other collaborators

Active, not recruiting

LITMUS Imaging Study

NAFLD | Fibrosis, Liver | NASH - Nonalcoholic Steatohepatitis | NASH | Steatosis of Liver

United Kingdom, Finland, Sweden, Spain, Greece, United States, Switzerland, Italy, France, Germany
National Institute of Allergy and Infectious Diseases...

Terminated

Investigation of Southern Tick-Associated Rash Illness (STARI)

Southern Tick-Associated Rash Illness

United States
Hepion Pharmaceuticals, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Rencofilstat in Adult Subjects With NASH F3 (ALTITUDE)

NASH With Fibrosis

United States
Fibronostics USA, Inc
OBVIO HEALTH USA, Inc.

Withdrawn

Validation of the LiverFASt Test and the Associated Fibrosis Staging Scores Compared to Liver Tissue Pathology Via Liver Biopsy

NAFLD | NASH

United States
1Globe Biomedical Co., Ltd.

Recruiting

Phase Ib/II Study to Evaluate the Efficacy and Safety of GH509 Versus Placebo in Patients With NASH/NAFLD

NAFLD | NASH

China
Hepion Pharmaceuticals, Inc.

Active, not recruiting

Single Dose ADME Study of [14C]-Rencofilstat in Healthy Male Subjects

NASH With Fibrosis

United Kingdom
Active Genomes Expressed Diagnostics, Corp
Walter Reed National Military Medical Center; Arizona Clinical Trials

Not yet recruiting

AGED Diagnostics Liver Disease Assessment (AGEDDX)

Healthy | NAFLD | NASH With Fibrosis

United States
Albireo

Completed

A Phase 2 Study of Elobixibat in Adults With NAFLD or NASH

NAFLD | NASH

United States
Beijing Friendship Hospital

Not yet recruiting

Precise Evaluation Criteria for Histological Regression of NASH Fibrosis

Liver Fibrosis | NASH
University of Wisconsin, Madison

Recruiting

An Imaging-based Quantitative Biomarker Assay for NAFLD in Children

NAFLD | NASH

United States
West Virginia University

Terminated

1% Topical Pimecrolimus Cream for the Treatment of the Rash Associated With ERBITUX

Rash

United States
Alnylam Pharmaceuticals

Terminated

A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis | NASH

United States, Bulgaria, United Kingdom, Belgium, Turkey
Northwestern University
GlaxoSmithKline

Completed

Histological Characterization and Differentiation of Rash From Other Epidermal Growth Factor Receptor (EGFR) Inhibitors

Skin Rash

United States
University of Pittsburgh
OSI Pharmaceuticals

Withdrawn

Study of Acitretin to Treat Skin Rash Caused by Erlotinib (a Chemotherapy Drug)

Skin Rash

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of MT-3995 in Patients With Non-Alcoholic Steatohepatitis(NASH)

NASH

Japan
Tasly Pharmaceutical Group Co., Ltd

Recruiting

HuHuangLianzonggan Capsule in Subjects With Nonalcoholic Steatohepatitis: a Phase 2 tRial(HHL-HEPAR)

NASH

China
Shupei Li

Recruiting

A Multicenter, Double-blind, Placebo-randomized Controlled Clinical Study on the Treatment of Non-alcoholic Steatohepatitis With Tibetan Drug Langqing Atar

NASH

China
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis

NASH

United States, Canada, Spain, Japan, Bulgaria
Institute of Liver and Biliary Sciences, India

Withdrawn

Fecal Microbiota Therapy Versus Standard Therapy in Decompensated NASH Related Cirrhosis: A Randomized Controlled Trial.

NASH Related Decompensated Cirrhosis

India
Guangdong Raynovent Biotech Co., Ltd

Recruiting

A Randomized, Double-blind, Placebo-controlled Study of ZSP1601 in Adult Subjects With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

China
Massachusetts General Hospital

Recruiting

Estrogen Administration for the Treatment of NASH in Postmenopausal Women

NASH - Nonalcoholic Steatohepatitis

United States
Lipocine Inc.

Completed

The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States
Indiana University
Sonic Incytes

Terminated

Quantitative Ultrasound With Liver Incytes for Evaluation of Non-Alcoholic Fatty Liver Disease

NAFLD | NASH - Nonalcoholic Steatohepatitis

United States
Akero Therapeutics, Inc

Active, not recruiting

A Study of Efruxifermin in Non-Cirrhotic Subjects With Histologically Confirmed Nonalcoholic Steatohepatitis (NASH) (Harmony)

NASH - Nonalcoholic Steatohepatitis

United States, Puerto Rico
CytoDyn, Inc.
Amarex Clinical Research

Completed

Leronlimab (PRO 140) in Patients With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States
Sinew Pharma Inc.

Terminated

An Open-Label Study to Assess the Hepatic Protection Effect of SNP-612, in Patients With NAFLD

NASH - Nonalcoholic Steatohepatitis

Taiwan
Meridian Bioscience, Inc.
Bristol-Myers Squibb

Completed

Companion Protocol for ¹³C-Methacetin Breath Tests in BMS: NCT03486899, NCT03486912 Referenced Trials

NASH - Nonalcoholic Steatohepatitis

United States

Clinical Trials on NASH/MASH

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