Search clinical trials for: Dose decrease

Total 7779 results

Kafrelsheikh University

Unknown

Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19 (Isotretinoin)

Covid19

Egypt
Sun Yat-sen University

Unknown

CyBorD vs. PAD in the Treatment of Newly Diagnosed Multiple Myeloma

Multiple Myeloma

China
Crucell Holland BV

Completed

Re-licensing Study to Assess Inflexal V Formulated With WHO Recommended Influenza Strains (2013-14)

Influenza

Switzerland
The Cleveland Clinic
Celgene Corporation

Withdrawn

Secondary Prophylaxis of Gastrointestinal Bleeding in Cirrhotic Patients Using THALIDOMIDE

Portal Hypertension | Gastrointestinal Hemorrhage

United States
Millennium Pharmaceuticals, Inc.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Phase 1/2 Study of VELCADE® in Combination With Other Drugs to Treat Previously Untreated Multiple Myeloma Patients (EVOLUTION)

Multiple Myeloma

United States
Third Military Medical University

Completed

A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients (HOT-ACME)

Hypertension | Obesity

China
University of Cologne

Completed

Feasibility and Efficacy of BACOPP-21 for Patients > 60 Years With Intermediate or Advanced Hodgkins Lymphoma

Hodgkin´s Lymphoma

Germany
University Health Network, Toronto
University Health Network, Toronto

Recruiting

Platform of Randomized Adaptive Clinical Trials in Critical Illness (PRACTICAL)

Respiratory Insufficiency | Extracorporeal Membrane Oxygenation Complication | Mechanical Ventilation Pressure High

United States, Canada, Australia, New Zealand, Spain, Colombia, Singapore, Italy, Saudi Arabia
National Cancer Institute (NCI)

Active, not recruiting

Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

HIV Infection | Tuberculosis

Peru, Brazil, South Africa, Haiti, Kenya
University Hospital, Strasbourg, France

Not yet recruiting

Evaluation of the Efficacy of Sublingual Sufentanil (Prescribed as Rescue Analgesia for Acute Postoperative Pain) on the Quality of Health Recovery After Surgery: a Randomized, Controlled, Multicenter, Open-label Trial Against an Active Comparator (SUBLIME) (SUBLIME)

Postoperative Pain

France
Brazilian Clinical Research Institute
Brainfarma Industria Química e Farmacêutica S/A

Completed

Fixed Combination of Dipyrone and Codeine for Controlling Pain After Pelvic-abdominal Surgery (DIPICOR)

Pain, Postoperative

Brazil
International Extranodal Lymphoma Study Group (IELSG)

Completed

Study on Tailored Treatment in Elderly Patients With Newly Diagnosed Primary Lymphoma of Central Nervous System (FIORELLA)

Primary Central Nervous System Lymphoma

Denmark, Finland, Switzerland, Italy
Candel Therapeutics, Inc.
Bristol-Myers Squibb; National Cancer Institute (NCI)

Completed

GMCI, Nivolumab, and Radiation Therapy in Treating Patients with Newly Diagnosed High-Grade Gliomas (GMCI)

Glioma, Malignant

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Rifampicin on the Pharmacokinetics of SHR6390 in Healthy Subjects

Healthy Subjects

China
Attikon Hospital
University Hospital of Patras

Unknown

Cilostazol Following Peripheral Endovascular Procedures (CILO-PER)

Peripheral Arterial Disease

Greece
The University of Texas Health Science Center at...
VA Office of Research and Development; National Center for Complementary and...

Completed

N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy

Diabetic Nephropathies | Proteinuria | Oxidative Stress

United States
Universidade Estadual Paulista Júlio de Mesquita...
University of Sao Paulo

Completed

Influence of Diabetes on Tramadol Pharmacokinetics

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus | Neuropathic Pain

Brazil
Boehringer Ingelheim

Terminated

Berodual® Respimat® vs Metered Dose Inhaler in Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive
Novartis Pharmaceuticals

Withdrawn

A 12 Week Study of QVA149 Compared to Fluticasone/Salmeterol (Advair) for Treatment of COPD

Chronic Obstructive Pulmonary Disease

Colombia, India, Belgium, Argentina, Czech Republic
Azienda Policlinico Umberto I

Unknown

Different Bowel Preparations for Colonoscopy In Children

Colonoscopy

Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Oligoprogressive Lung Non-Small Cell Carcinoma

United States
Novartis Pharmaceuticals

Completed

Asciminib Treatment Optimization in ≥ 3rd Line CML-CP

Chronic Myelogenous Leukemia

Spain, United Kingdom, Canada, Austria, France, Greece, Singapore, Italy, Germany, Argentina, Vietnam, Malaysia, Poland, South Korea, Brazil, Oman
Bristol-Myers Squibb

Completed

A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)

Unresectable or Metastatic Melanoma

United States, Germany, Italy, United Kingdom, Canada, Denmark, Netherlands, Spain, Belgium, France, Switzerland, Israel, Austria, Brazil
Universidade Federal de Santa Maria

Completed

Antioxidants Combined With Cryotherapy on Inflammatory Response After Resistance Exercise in Untrained Volunteers

Pain | Inflammation | Oxidative Stress

Brazil
Forest Laboratories

Completed

Bioavailability Study of Anti Nausea Medication With and Without Food (EUR-1025) (ODO-P8-689)

Nausea
BonusBio Group Ltd

Completed

Filling Bone Defects/Voids With Autologous BonoFill For Maxillofacial Bone Regeneration

Bone Void in the Maxillofacial Area

Israel
Centre Muraz
Institute of Tropical Medicine, Belgium

Completed

In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso

Malaria

Burkina Faso
Cairo University

Not yet recruiting

Effect of Manual Therapy on Migraine in Postmenopausal Women

Migraine

Egypt
University of California, Irvine
Icahn School of Medicine at Mount Sinai; Duke University

Completed

Brain Dopamine Function in Adults With ADHD (Brookhaven)

Attention Deficit Hyperactivity Disorder

United States
Carol Fabian, MD
Breast Cancer Research Foundation

Terminated

Pilot Study of Effects of Duavee® on Imaging and Blood Biomarkers In Women With Menopausal Symptoms

Focus of Study is Healthy Women at Risk for Breast Cancer

United States
National Hepatology & Tropical Medicine Research...

Completed

Ondansetron Effect on Pain Relief After Laparoscopic Cholecystectomy

Cholecystitis

Egypt
University of Manitoba
Health Sciences Centre, Winnipeg, Manitoba; University of Utah; St. Boniface... and other collaborators

Unknown

Budesonide With Intratracheal Surfactants in Extremely Preterm Infants (BITS)

Bronchopulmonary Dysplasia | Respiratory Distress Syndrome in Premature Infant

Canada
St. Justine's Hospital

Completed

Ondansetron for Pediatric Mild Traumatic Brain Injury

Traumatic Brain Injury | Brain Concussion

Canada
University of Pennsylvania
Merck Sharp & Dohme LLC; The Dana Foundation; Kos Pharmaceuticals

Completed

Carotid Atherosclerosis Regression at Magnetic Resonance Assessment.

Established Carotid Atherosclerosis
Spanish Clinical Pharmacology Society
Spanish reumatology Society

Completed

Evaluation of a Protocol for Dose Reduction in Patients With Spondylarthropathies and Clinical Remission With Anti-TNF (REDES-TNF)

Spondylarthropathies

Spain
Peking University Third Hospital

Recruiting

Evaluation of the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Diabetic Patients

Diabetes

China
National Cancer Institute (NCI)

Withdrawn

RO4929097 After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma

Refractory Plasma Cell Myeloma | DS Stage I Plasma Cell Myeloma | DS Stage II Plasma Cell Myeloma | DS Stage III Plasma Cell Myeloma

United States
Tanta University

Not yet recruiting

This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcting Early-onset Vitamin B12 Deficiency in Adult Patients Using Proton Pump Inhibitors (PPIs). The Primary Outcome is the Change in Serum Vitamin B12 Levels Over a 6-week

Hypovitaminosis b 12
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Comparison of the Antiplatelet Efficacy of Aspirin Combined With Clopidogrel and Aspirin Combined With Half-dose Ticagrelor in Patients With Unruptured Intracranial Aneurysms With Normal CYP2C19 Metabolizer Phenotype

Intracranial Aneurysms | Antiplatelet Drugs
Sichuan University

Recruiting

Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC

Lung Cancer | Extensive-stage Small-cell Lung Cancer

China
Obafemi Awolowo University Teaching Hospital
Open Philanthropy

Recruiting

ATORvastatin in Pulmonary TUBerculosis (ATORTUB)

Tuberculosis | Pulmonary Tuberculosis | Koch's Disease

Nigeria
West China Hospital

Recruiting

Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features II

Hepatitis, Autoimmune | Primary Biliary Cholangitis

China
National Heart, Lung, and Blood Institute (NHLBI)
Novartis

Active, not recruiting

Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

Severe Aplastic Anemia

United States
University of Utah

Completed

pAF for the Treatment of Osteoarthritis

Osteo Arthritis Knee

United States
Celgene

Active, not recruiting

Efficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM) (KarMMa-3)

Multiple Myeloma

United States, Belgium, Canada, France, Germany, Italy, Japan, Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom
Andres J. M. Ferreri

Completed

Short Term Intensified Chemo-immunotherapy in HIV-positive Patients With Burkitt Lymphoma (CARMEN)

HIV | Burkitt's Lymphoma

Italy
Laboratorios Silanes S.A. de C.V.

Completed

Pharmacokinetic Interaction Between Ibuprofen and Acetaminophen, Tablets Administered Individually or in Combination

Healthy

Mexico
MEDA Pharma GmbH & Co. KG

Completed

MP-AzeFlu Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
Oxford University Hospitals NHS Trust
University of Warwick; University of Birmingham; Janssen-Cilag Ltd.; Bloodwise

Completed

Optimising Renal Outcome in Myeloma Renal Failure (OPTIMAL)

Multiple Myeloma | Chronic Kidney Disease

United Kingdom

Search clinical trials for: Dose decrease

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