Search clinical trials for: Dose decrease

Total 7779 results

Brown University
Lifespan; SouthCoast Medical Group; Memorial hospital

Completed

BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial

Metastatic Pancreatic Cancer

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Cyclosporine, Pravastatin Sodium, Etoposide, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
Samsung Medical Center
The Korean Urological Association

Withdrawn

The Clinical Efficacy of Non-steroidal Anti-inflammation Drugs in Patients With Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia

Korea, Republic of
Second Affiliated Hospital, School of Medicine,...

Recruiting

Sertraline Combined With Fluvoxamine in the Treatment of Refractory Obsessive-compulsive Disorder

OCD

China
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

Gastric Neuroendocrine Carcinoma | Intestinal Neuroendocrine Carcinoma | Pancreatic Neuroendocrine Carcinoma

United States
M.D. Anderson Cancer Center
Dana-Farber Cancer Institute

Active, not recruiting

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

United States
University of Florida
Accelerate Brain Cancer Cure; Lyla Nsouli Foundation

Terminated

Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) (BRAVO)

Brain Stem Glioma | Diffuse Intrinsic Pontine Glioma (DIPG)

United States
Zosano Pharma Corporation

Completed

A Four-way Crossover Study of 3 Formulations of M207 With Intranasal Zolmitriptan in Healthy Volunteers

Migraine

United States
Military Institute of Medicine, Poland

Completed

Non-invasive Haemodynamic Assessment in Hypertension (FINE-PATH)

Arterial Hypertension

Poland
Boston University
National Institute of Mental Health (NIMH); Massachusetts General Hospital; New... and other collaborators

Active, not recruiting

Supporting Sustained HIV Treatment Adherence After Initiation (SUSTAIN)

HIV Infections | Adherence, Medication

South Africa
Franciscus Gasthuis
Erasmus Medical Center; TNO

Active, not recruiting

Phenotyping and Classifying Asthma Exacerbations (ExCluSieF)

Asthma Attack

Netherlands
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)

Mental Disorders | Dyssomnias | Insomnia | Sleep Initiation and Maintenance Disorders | Sleep Disorders
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Phase 2 Study of Rituximab-ABVD in Classical Hodgkin Lymphoma

Lymphoma

United States
Ocular Therapeutix, Inc.

Completed

Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Glaucoma

Glaucoma

South Africa
Radboud University Medical Center
Sanofi; European and Developing Countries Clinical Trials Partnership (EDCTP); National Institute for Public Health and the Environment (RIVM) and other collaborators

Completed

Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis (High RIF)

Tuberculosis

Tanzania
Christian Medical College, Vellore, India
Medical Research Council; India Alliance

Recruiting

Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy? (IA-GRACE-IgANT)

Renal Insufficiency, Chronic | IgA Nephropathy | IGA Glomerulonephritis | IgA Vasculitis

India
Mayo Clinic

Not yet recruiting

Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain

Endometrial Carcinoma

United States
David S Shulman, MD
Peel Therapeutics Inc

Recruiting

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

Sarcoma | Osteosarcoma | Sarcoma, Ewing | Rhabdomyosarcoma | Refractory Sarcoma | Desmoplastic Small Round Cell Tumor

United States
Abbisko Therapeutics Co, Ltd

Completed

A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021

Healthy Subjects

China
National Cancer Institute, Egypt

Completed

Magnesium Versus High Dose Fentanyl in Endotracheal Intubation

Stress Response

Egypt
Merck Sharp & Dohme LLC

Completed

Effect of Infliximab on the Efficacy of Peg-Intron/Ribavirin in Patients With Hepatitis C (Study P04257AM4)(COMPLETED) (Pegade)

Hepatitis C, Chronic
Universidad Autonoma de Nuevo Leon

Completed

Therapeutic Effect of Botulinum Toxin A for the Treatment of Plantar Fasciitis.

Plantar Fascitis | Botulinum Toxins, Type A

Mexico
VA Office of Research and Development
National Center for Complementary and Integrative Health (NCCIH)

Completed

N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy (CGDN)

Diabetic Nephropathy | Proteinuria | Oxidative Stress

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Genentech, Inc.

Terminated

R-ICE and High-Dose Cyclophosphamide With PET/CT for Diffuse Large B-Cell Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United States
Memorial Sloan Kettering Cancer Center
Celgene Corporation

Completed

Lenalidomide in Patients With Chronic Lymphocytic Leukemia Older Than 65 Years of Age

Leukemia | Chronic Lymphocytic Leukemia

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Brain and Central Nervous System Tumors

Germany
Iovance Biotherapeutics, Inc.

Terminated

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Squamous Cell Carcinoma of the Head and Neck | Metastatic Melanoma | Non-small Cell Lung Cancer

United States, Spain, Switzerland, Canada, Greece, United Kingdom, Germany
M.D. Anderson Cancer Center

Completed

Prophylactic Use of Filgrastim SD/01 in Patients With Hodgkin's Disease Receiving ABVD Chemotherapy

Hodgkin Disease

United States
Merck Sharp & Dohme LLC
Parexel

Completed

A Six Week, Double-Blind Randomized, Efficacy and Safety, Sleep Lab Trial With Esmirtazapine (Org 50081) (P05707)

Insomnia
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer

Prostate Cancer | Pharmacokinetics of Dextromethorphan | Pharmacokinetics of Caffeine

Moldova, Republic of
VA Office of Research and Development

Completed

Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients (PONV)

Postoperative Nausea and Vomiting

United States
Novo Nordisk A/S

Completed

Comparison of Explorative Formulation of Insulin Degludec and Insulin Aspart Co-formulation Versus Explorative Formulation of Insulin Degludec and Insulin Aspart Separately Compared With Biphasic Insulin Aspart 30 in Male Subjects With Diabetes

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Germany
AGIR à Dom
AIR LIQUIDE MEDICAL SYSTEMS

Not yet recruiting

Evaluation of the Comfort of a Continuous Positive Airway Pressure Nasal Mask in the Treatment of OSA Syndrome (NINADOM)

Apnea, Obstructive

France
Dr. Diane Lougheed

Recruiting

Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol

Cough | Asthma | Cough Variant Asthma

Canada
Xiayun He, MD

Completed

Reduced Target Delineation and Radiation Doses Chemoradiotherapy for Patients With Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Shanghai HEP Pharmaceutical Co., Ltd.
Shanghai Tong Ren Hospital; Shanghai East Hospital

Completed

A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients

Chronic Hepatitis B

China
Bayer

Completed

Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed

Pain, Postoperative

United States
Sunovion

Completed

Pediatric Open-Label Extension Study

Schizophrenia | Bipolar Depression | Autism

Korea, Republic of, United States, Malaysia, Bulgaria, Poland, Mexico, Colombia, France, Hungary, Philippines, Puerto Rico, Romania, Russian Federation, Spain, Ukraine
Avekshan LLC

Completed

Study for Naltrexone on the Abuse Potential of Methylphenidate

Naltrexone | Methylphenidate Abuse

United States
James Gossage
HHT Foundation International

Completed

North American Study of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) (NOSE)

Epistaxis | Telangiectasia, Hereditary Hemorrhagic

United States
Khon Kaen University

Completed

Effects of Intraoperative Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Microvascular Decompression Surgery

Postoperative Nausea and Vomiting | Microvascular Decompression Surgery

Thailand
AstraZeneca

Completed

Real Life Effectiveness in Asthma of Symbicort Single Inhaler Therapy (RELEASE)

Asthma

United Kingdom
Tianjin Medical University Second Hospital

Recruiting

Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment Exhaustion

Solid Tumor | Precision Medicine

China
Grupo de Investigación Clínica en Oncología Radioterapia
Hospital del Mar; Hospital Universitari Sant Joan de Reus; Hospital Universitario...

Recruiting

Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19

Pneumonia, Viral

Spain
Paul Szabolcs

Recruiting

Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure

Idiopathic Pulmonary Fibrosis | Emphysema or COPD

United States
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University; University of Washington; H. Lee...

Completed

A Phase 2 Multicenter Study of High Dose Chemotherapy With Autologous Stem Cell Transplant Followed by Maintenance Therapy With Romidepsin for the Treatment of T Cell Non-Hodgkin Lymphoma

T Cell Non-Hodgkin Lymphoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women Who Take Nevirapine During Pregnancy

HIV Infections

Tanzania, Haiti, Malawi, South Africa, India, Uganda
University of California, San Francisco

Completed

Pharmacokinetic Study in Patients With Chronic Kidney Disease and Healthy Volunteers (CKD)

Kidney Disease

United States
Astellas Pharma Inc

Completed

To Evaluate Whether Acetyl Salicylic Acid (Aspirin), the Combination of Aspirin and Clopidogrel and Darexaban (YM150) Interact in Their Effects

Healthy Subjects | Pharmacodynamic Interaction

France

Search clinical trials for: Dose decrease

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