Search clinical trials for: Dose decrease

Total 7779 results

Medigen Vaccine Biologics Corp.

Completed

A Study to Evaluate MVC-COV1901 Vaccine Against COVID-19 in Elderly Adults

Covid19 Vaccine

Taiwan
University of Aarhus

Completed

Bioavailability of Anthocyanins From Aronia Extract in Healthy Men - a Pilot Study

Bioavailability

Denmark
Genuine Research Center, Egypt
Eva Pharma

Completed

Bioequivalence Study of Ivermectin From Revemact 6 mg Tablets (Man. by EVA Pharma for Horus for Pharmaceutical Industries, Egypt) and Stromectol 2*3 mg Tablets (Merck Sharp & Dohme B.V., Haarlem, The Netherlands)

Healthy

Egypt
Bristol-Myers Squibb

Withdrawn

Evaluate the Bioavailability Between 2 BMS-986141 Formulations in Healthy Participants

Healthy
Shanghai Greenvalley Pharmaceutical Co., Ltd.
Shanghai Mental Health Center

Completed

Safety, Efficacy and Dose Titration of Sodium Oligo-mannurarate Capsule on Mild to Moderate Alzheimer's Disease

Cognitive Impairment | Alzheimer Disease

China
University of Bergen
Olympic Seafood AS

Completed

Krill Oil as Supplementation to Healthy Young Adults.

Healthy

Norway
ScinnoHub Pharmaceutical Co., Ltd.

Recruiting

Evaluation of Safety, Efficacy, and Pharmacokinetics of BT-114143 Injection in Patients With Abnormal Uterine Bleeding

Abnormal Uterine Bleeding

China
Pfizer

Completed

Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

Staphylococcal Infections

United States
Bayer

Completed

Cycle Control and Safety of E2-DRSP

Contraceptive, Oral, Hormonal

Germany
Enterprise Therapeutics Ltd

Completed

A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects

Healthy

United Kingdom
Charles Drew University of Medicine and Science

Completed

The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels

Oxidative Stress

United States
Immunocore Ltd

Withdrawn

Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, United States, Spain, Australia, Denmark, Taiwan, Romania, United Kingdom
Beijing Tiantan Hospital

Completed

Minimally Invasive Surgery and RhTNK-tPA for Intracerebral Hemorrhage Evacuation

Cerebrovascular Disorders | Hemorrhage | Intracranial Hemorrhages | Cerebral Hemorrhage

China
Bausch & Lomb Incorporated

Completed

Safety, Pharmacokinetics, and Efficacy of Bepotastine Besilate Nasal Product After Ragweed Pollen Exposure in an Environmental Chamber

Seasonal Allergic Rhinitis

United States
Hospital Ana Nery

Unknown

Intensive Versus Conventional Digoxin Use in Patients With Heart Failure (ICHF)

Heart Failure

Brazil
Boehringer Ingelheim

Completed

Dose Escalation Study With 99mTC - or 186 Re-labelled Humanised Monoclonal Antibody (hMAb) BIWA 4 in Patients With Head and Neck Cancer

Head and Neck Neoplasms
University Hospital, Antwerp

Completed

Standardised Drug Provocation Testing in Perioperative Hypersensitivity

Hypersensitivity | Anaphylaxis | Allergic Reaction | Perioperative Complication | Immediate Hypersensitivity | Hypersensitivity, Drug | Anaphylactic Reaction

Belgium
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Oral Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-281959 / ACT-246475 in Healthy Male Subjects

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

France
MAXVAX Biotechnology Limited Liability Company
Henan Center for Disease Control and Prevention

Active, not recruiting

Safety and Immunogenicity of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 18 Years and Above

Herpes Zoster

China
Emergent BioSolutions

Completed

Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy Adults

Typhoid

United States
Children's Hospital Los Angeles
Lucile Packard Children's Hospital

Terminated

Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells

Metabolic Diseases | Stem Cell Transplantation | Chronic Granulomatous Disease | Bone Marrow Transplantation | Thalassemia | Wiskott-Aldrich Syndrome | Genetic Diseases | Peripheral Blood Stem Cell Transplantation | Pediatrics | Diamond-Blackfan Anemia | Allogeneic Transplantation | Combined Immune Deficiency | X-linked Lymphoproliferative Disease
Boehringer Ingelheim

Completed

Efficacy and Safety of Telmisartan and Losartan in Primary Hypertension

Hypertension
Biocad

Recruiting

Clinical Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Crohn's Disease (COMANDOR)

Crohn's Disease (CD)

Russia
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Taiwanese Adults 65 Years of Age and Older

Influenza (Healthy Volunteers)

Taiwan
Medical University of South Carolina

Completed

Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE)

Systemic Lupus Erythematosus

United States
Radboud University Medical Center
UMC Utrecht; Amsterdam UMC, location VUmc; Maastro Clinic, The Netherlands; Rad...

Completed

Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity (UPGRADE-RT)

Head and Neck Neoplasms | Carcinoma, Squamous Cell

Netherlands
Mayo Clinic
Regenerative Medicine Minnesota

Terminated

Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetic Kidney Disease | Diabetic Nephropathies | Chronic Kidney Disease | Kidney Failure | Diabetic Nephropathy Type 2 | Kidney Insufficiency

United States
Miltenyi Biomedicine GmbH
ICON plc

Completed

Safety of MB-CART2019.1 in Lymphoma Patients (MB-CART2019.1 Lymphoma / DALY 1)

B-cell Non Hodgkin Lymphoma

Germany
Ottawa Hospital Research Institute
The Ottawa Hospital Academic Medical Association; Canadian Association of Emergency...

Completed

High-dose vs. Standard-dose Cephalexin for Cellulitis

Cellulitis

Canada
Zhejiang Cancer Hospital

Completed

Different Radiation Dose of Neoadjuvant Chemoradiation for Resectable Thoracic Esophageal Squamous Carcinoma (Neo-DRATEC)

Surgery | Esophageal Carcinoma | Neoadjuvant Chemoradiotherapy

China
Pfizer

Completed

A Preliminary Study to Evaluate PF-07264660 in Healthy Participants

Healthy

United States
Ohio State University

Completed

A Pilot Study: High Versus Low Oxytocin Dosing for Induction of Labor in Pregnant Patients With Obesity (HILIO-PILOT)

Pregnant Patients With Obesity

United States
Dong-A ST Co., Ltd.

Completed

Study to Evaluate the Efficacy and Safety of Intra-articular DA-5202 in Patients With Osteoarthritis of the Knee

Osteoarthritis, Knee

Korea, Republic of
Taiho Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety Study of TAS5315 Compared With Placebo in Participants With Rheumatoid Arthritis.

Rheumatoid Arthritis

Japan
Georgetown University

Unknown

Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Parkinson's Disease (PD Nilotinib)

Parkinson Disease | Parkinsons Disease With Dementia

United States
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 4, 2012

Influenza
Access Business Group
Fudan University; Sprim Advanced Life Sciences; Sinphar Pharmaceutical Co., Ltd

Completed

Effect of Ginko and Cistanche Against Fatigue Symptoms (GkoCist)

Fatigue | Mental Fatigue | Chronic Fatigue Syndrome
Beijing Bozhiyin T&S Co., Ltd.

Unknown

To Evaluate the Efficacy and Safety of Wenxin Keli in Treating Atrial Premature Beats

Atrial Premature Beats

China
Cumberland Pharmaceuticals

Completed

2 Regimens of Lactulose for Colonoscopy Preparation in Adults

Colonoscopy Preparation

United States
Braintree Laboratories

Completed

A Safety and Efficacy Evaluation of BLI801 Laxative in Constipated Adults

Constipation

United States
Alfonso Gomez-Iturriaga
Hospital de Cruces

Unknown

Dose Escalation to Dominant Intraprostatic Lesions (DIL) With MRI-TRUS Fusion High Dose Rate (HDR) Prostate Brachytherapy (BRAPROST)

Prostate Cancer

Spain
National Cardiovascular Center Harapan Kita Hospital...

Completed

Can Oral T3 Normalize Thyroid Hormone Levels Following Cardiopulmonary Bypass in Children?

Low T3 Syndrome

Indonesia
Radboud University Medical Center
Sanofi

Unknown

TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer (Condor)

Head and Neck Cancer

Netherlands
Boehringer Ingelheim

Completed

Effects of Tipranavir/Ritonavir on the Pharmacokinetic Characteristics of Triple Drug Nucleoside and Non-nucleoside Reverse Transcriptase Inhibitor Therapy in HIV-1-infected Subjects

HIV Infections
Medical College of Wisconsin

Recruiting

MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

Rectal Adenocarcinoma

United States
Wenshan City People's Hospital

Not yet recruiting

Protein Intake Dosage on the Prognosis of Neurocritical Patients

Ischemic Stroke | Traumatic Brain Injury | Neurocritical Conditions
Biocad

Recruiting

Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Ulcerative Colitis (ULTRAMARINE)

Ulcerative Colitis (UC)

Russia
Themis Bioscience GmbH

Completed

Safety and Immunogenicity of a Novel Vaccine Formulation MV-ZIKA-RSP (V187-001) (MV-ZIKA-RSP)

Zika Virus Infection

Austria
Novartis Pharmaceuticals

Recruiting

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01) (TulmiSTAR-01)

Progressive Metastatic Castrate Resistant Prostate Cancer

Australia, France, Spain, United Kingdom, United States, Italy, Malaysia, Singapore, China, Canada, Denmark, Germany, Poland, Mexico
Hannah Harris
National Institute on Drug Abuse (NIDA)

Recruiting

Repeated CBD Administration and Cannabis Outcomes

Cannabis | Experimental Pain in Healthy Human Participants | Abuse Liability

United States

Search clinical trials for: Dose decrease

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