Search clinical trials for: Dose decrease

Total 7779 results

Mabylon AG

Recruiting

Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy

Peanut Allergies

United States
Anagram Therapeutics, Inc.

Completed

Phase 1 Study to Assess Safety and Efficacy of ANG003

Exocrine Pancreatic Insufficiency

United States
GlaxoSmithKline

Completed

The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury

Lung Injury, Acute

United States, Canada
AstraZeneca

Completed

Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects (BA)

Healthy Volunteers | Pharmacologic Action

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

A Clinical Study of T3011 in Combination With PD-1/PD-L1 Inhibitors in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

China
Alimorad Farshchian

Recruiting

Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain

Back Pain | Facet Joint Pain | Facet Joints; Degeneration

United States
Toronto Metropolitan University
Anderson Advanced Ingredients

Completed

Effect of Allulose on Diet-induced Thermogenesis

Diet Induced Thermogenesis

Canada
Galapagos NV

Completed

Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation) (SAPHIRA1)

Cystic Fibrosis

United Kingdom, Australia, Ireland, Germany, Czech Republic
Sun Pharmaceutical Industries Limited

Recruiting

Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus

Type II Diabetes Mellitus

United States, India
Spanish National Research Council

Not yet recruiting

Erythrodiol in Pomace Olive Oil as a Protective Agent Against Atherosclerosis

Atherosclerosis Cardiovascular Disease

Spain
Lexeo Therapeutics

Active, not recruiting

Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia

Friedreich Ataxia | Cardiomyopathy, Secondary

United States
Galapagos NV

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2737 in Healthy Subjects

Healthy

Netherlands
Biocad

Completed

Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of Single Escalating Doses of BCD-180 in Healthy Volunteers

Healthy

Russian Federation
AstraZeneca
Parexel

Active, not recruiting

A Phase I Study Comparing the Relative Bioavailability of a Fixed-Dose Combination of Laroprovstat/Rosuvastatin vs Their Single Therapy Products in Healthy Adults

Healthy Participants

United States
Edgewise Therapeutics, Inc.

Active, not recruiting

Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy (FOX)

Duchenne Muscular Dystrophy

United States
Samjin Pharmaceutical Co., Ltd.

Completed

Clinical Study to Investigate the Efficacy of Orally Administered SA001 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome (pSS)

Korea, Republic of
University of Missouri-Columbia
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

A Controlled Study of the Safety and Efficacy of Lessertia Frutescens in HIV-infected South African Adults

HIV Infections

South Africa
University of Chicago

Active, not recruiting

Radiation Dose Study for Relapsed/Refractory Hodgkin/Non-Hodgkin Lymphoma

Lymphoma | Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
Galapagos NV

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG3067 in Healthy Subjects.

Healthy

Belgium
MediBeacon

Completed

Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

Acute Kidney Injury

United States
University Hospital, Angers

Recruiting

Effects of Increasing Mean Arterial Pressure on Renal Function in Patients With Shock and With Elevated Central Venous Pressure (MAPAKI)

Shock

France
Shanghai Henlius Biotech

Recruiting

A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors

Non Small Cell Lung Cancer | Solid Tumor Cancer

China
Taiho Pharmaceutical Co., Ltd.

Completed

A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

Japan
Instituto de Investigación Sanitaria de la Fundación...
Effice Servicios Para la Investigacion S.L.

Active, not recruiting

Clinical Trial to Evaluate Safety and Efficacy of Cell Therapy in Patients With Cicatricial Conjuntivitis. (CELOPHIN)

Stevens-Johnson Syndrome | Lyell Syndrome | Pemphigoid | Chronic Conjunctivitis

Spain
Boehringer Ingelheim

Completed

Single Rising Dose Study of BI 207127 NA in Healthy Male Asian Volunteers and Single Dose Study of BI 207127 NA in Healthy Male Caucasian Volunteers

Healthy

Korea, Republic of
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Efficacy Study of VIS649 for IgA Nephropathy

Immunoglobulin A Nephropathy | Glomerular Disease | IgAN

United States, Australia, Canada, Hong Kong, Japan, Malaysia, Philippines, Singapore, Spain, Sri Lanka, Taiwan, Thailand, United Kingdom, India, South Korea
Aronora, Inc.

Completed

Safety and Efficacy Study of AB023 (Xisomab 3G3) in End Stage Renal Disease Patients on Chronic Hemodialysis

Thrombosis | End Stage Renal Disease

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Treatment of B-CLL With Human IL-2 and CD40 Ligand and Plasmid Gene Modified Autologous Tumor Cells (CLIPA)

Leukemia | Leukemia, B-Cell, Chronic

United States
Peking University Cancer Hospital & Institute

Not yet recruiting

Abemaciclib Dose Escalation in Early High-Risk Breast Cancer Adjuvant Therapy (ADES)

HR+/HER2- Breast Cancer
Institute of Hematology & Blood Diseases Hospital...

Recruiting

The Safety and Efficacy of Umbilical Cord Blood Mononuclear Cells in Patients With Secondary Poor Graft Function After Hematopoietic Stem Cell Transplantation

Poor Graft Function

China
National Cancer Institute, Egypt

Recruiting

Multimodality- Adapted Dose Modification in Head and Neck Cancer Radiation Therapy (MART)

Head and Neck Cancer

Egypt
Tata Medical Center

Completed

Dose Escalation Versus Standard in Laryngopharyngeal Cancers (INTELHOPE)

Malignant Neoplasm of Oropharynx Stage III | Malignant Neoplasm of Larynx Stage III | Malignant Neoplasm of Hypopharynx Stage III | Malignant Neoplasm of Oropharynx Stage IVa | Malignant Neoplasm of Oropharynx Stage IVb | Malignant Neoplasm of Larynx Stage IV | Malignant Neoplasm of Hypopharynx... and other conditions

India
Institute of Cancer Research, United Kingdom
Algok Bio Inc.

Recruiting

Investigating Idetrexed and Olaparib in Patients With Ovarian Cancer (IDOL)

High Grade Serous Ovarian Cancer

United Kingdom
HK inno.N Corporation

Unknown

A Study to Evaluate Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of IN-C005 in Healthy Male Subjects

Healthy

Korea, Republic of
Ting Chang, MD
Hebei Senlang Biotechnology Co., LTD

Active, not recruiting

The Safety and Efficacy of S103 in the Treatment of Refractory Generalized Myasthenia Gravis

Myasthenia Gravis, Generalized

China
GlaxoSmithKline
CureVac

Completed

A Study on the Safety, Reactogenicity and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

Influenza, Human

Belgium, Spain, Canada
University of Oxford

Completed

Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.

Chikungunya | Zika

Mexico
Novartis Vaccines

Completed

Safety and Immunogenicity Evaluation After One or Two Doses of Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Infants and Toddlers

Meningococcal Meningitis

Germany
GlaxoSmithKline

Not yet recruiting

A Study of Investigational RSV/hMPV Combination and Investigational hMPV Vaccines in Younger and Older Adults

Respiratory Syncytial Virus Infections+Metapneumovirus

Australia
Kyowa Kirin Co., Ltd.

Completed

A Study of Single and Multiple Doses of KW-6356 in Healthy Subjects

Parkinson's Disease

Japan
J2H Biotech

Completed

Investigate Safety, Tolerability, PK/PK of J2H 1702 in Healthy Males

Non-alcoholic Steatohepatitis

South Korea
Shanghai Henlius Biotech

Recruiting

A Phase II Clinical Study to Evaluate HLX43 in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Carcinoma of Head and/or Neck

China
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Completed

The Safety and Tolerability of WS016 in Healthy Chinese Volunteers

Hyperkalemia

China
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Withdrawn

Immunogenicity and Safety of COVID-19 Vaccine in Population Aged 18 Years and Above

COVID-19

China
University of Utah
National Cancer Institute (NCI)

Recruiting

Reach Through Equitable Implementation in Utah (REI-UT)

Tobacco Use | Tobacco Smoking | Tobacco Use Cessation | Tobacco Dependence | Tobacco Chewing

United States
Maria Sklodowska-Curie National Research Institute...

Recruiting

Optimal Radiotherapy - Heel Spur Syndrome - Randomized Clinical Trial (ORHEELS)

Heel Spur Syndrome

Poland
Haisco Pharmaceutical Group Co., Ltd.

Completed

Evaluating the Efficacy and Safety of of HSK44459 in People With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

China
Emmecell

Completed

Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema

Endothelial Dysfunction | Corneal Edema | Fuchs Dystrophy | Corneal Endothelial Dystrophy | Bullous Keratopathy | Pseudophakic Bullous Keratopathy | Corneal Endothelial Dysfunction | Fuchs Endothelial Corneal Dystrophy | Moderate Corneal Endothelial Decompensation

United States
AsclepiX Therapeutics, Inc.

Active, not recruiting

Safety and Bioactivity of AXT107 in Subjects With Neovascular Age-Related Macular Degeneration (nAMD) (DISCOVER)

Neovascular Age-related Macular Degeneration

United States
Innovent Biologics (Suzhou) Co. Ltd.

Terminated

A Safety, Tolerability, and Efficacy Study of IBI314 in Patients With Mild to Moderate COVID-19

COVID-19

China

Search clinical trials for: Dose decrease

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