Search clinical trials for: Dose decrease

Total 7787 results

AIM Vaccine Co., Ltd.
Ningbo Rongan Biological Pharmaceutical Co. Ltd.; LiveRNA Therapeutics Inc.

Not yet recruiting

Clinical Study of SARS-CoV-2 Variant mRNA Vaccine in Healthy Participants

SARS-CoV-2
Siriraj Hospital

Active, not recruiting

Hypofractionated Whole Pelvic Chemoradiotherapy With iRex Optimization in Cervical Cancer (HYPOCx-iRex)

Cervical Cancer

Thailand
University Hospital, Lille

Completed

Utility of Sodium Lactate Infusion During Septic Shock (ULIS1)

Septic Shock

France
Centre Hospitalier Universitaire de Nīmes
Centre Hospitalier Lyon Sud; Hôpital Haut-Lévêque

Completed

Pharmacokinetics of High-dose Ceftobiprole in Community-acquired Pneumonia Under Mechanical Ventilation. (PAC CEF)

Pneumonia

France
Tor Biering-Sørensen
Sanofi; Statens Serum Institut

Completed

A Pragmatic Randomized Trial to Evaluate the Effectiveness of High-Dose Quadrivalent Influenza Vaccine vs. Standard-Dose Quadrivalent Influenza Vaccine in Older Adults (DANFLU-2)

Influenza

Denmark
British Columbia Cancer Agency

Active, not recruiting

Comparison of HDR Vs. LDR Brachytherapy As Monotherapy for Intermediate Risk Prostate Cancer

Prostate Cancer

Canada
Vanderbilt University Medical Center
Aminu Kano Teaching Hospital; Murtala Muhammed Specialist Hospital

Completed

Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa (SPRINT)

Stroke | Sickle Cell Disease | Sickle Cell Anemia

Nigeria
Jonsson Comprehensive Cancer Center

Withdrawn

Focal Radiation Therapy for the Treatment of Low or Intermediate-Risk Prostate Cancer

Prostate Adenocarcinoma | Stage II Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage IIA Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8 | Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8

United States
University of Utah

Completed

Real-time Anti-Factor Xa Measurements in Surgical Patients to Examine Enoxaparin Metabolism and Optimize Enoxaparin Dose

Venous Thromboembolism | Deep Venous Thrombosis | Pulmonary Embolus

United States
GlaxoSmithKline

Completed

Study to Evaluate the Pharmacokinetics, Safety and Tolerability of GSK557296 in Healthy Women Volunteers After Single and Repeat Dosing

Embryo Transfer

United States
Sanofi Pasteur, a Sanofi Company

Completed

A Study of Fluzone® High-Dose Vaccine Compared With Fluzone® Vaccine In Elderly Adults

Influenza

United States, Puerto Rico, Canada
Jiangsu Province Centers for Disease Control and...
Beijing Tiantan Biological Products Co., Ltd.

Completed

Study of Evaluating Safety and Immunogenicity of 10µg/0.5ml Hepatitis B Vaccine

Hepatitis B

China
Gilead Sciences

Completed

A Study Evaluating GS-9620 in Virologically Suppressed Subjects With Chronic Hepatitis B Virus Infection

Hepatitis B

Korea, Republic of, United States, Canada, Australia, New Zealand
Uniformed Services University of the Health Sciences
Naval Medical Research Center; Navy Bureau of Medicine and Surgery; Ministry... and other collaborators

Terminated

Trial Evaluating Ambulatory Treatment of Travelers' Diarrhea (TrEAT TD)

Acute Watery Diarrhea | Dysentery/Febrile Diarrhea

Afghanistan, Djibouti, Honduras, Kenya, Thailand
Jiangsu Cancer Institute & Hospital

Not yet recruiting

Perioperative Chemotherapy With Low-Dose Radiotherapy and Tislelizumab for Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Gastric or Gastroesophageal Junction Adenocarcinoma
ScinnoHub Pharmaceutical Co., Ltd.

Recruiting

Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty（TKA） (TKA)

Total Knee Arthroplasty

China
Shanghai Bovax Biotechnology Co., Ltd.

Recruiting

To Evaluate the Safety and Immunogenicity of 15-valent HPV Recombinant Vaccine in Chinese People Aged 9-45 Years

HPV Infection | HPV-Related Carcinoma | Genital Wart | HPV-Related Intraepithelial Neoplasia

China
Akeso

Recruiting

Combination Therapy of AK112 With Chemotherapy and/or Olaparib in Platinum-sensitive Ovarian Cancer

Platinum-sensitive Ovarian Cancer

China
Prince of Songkla University

Recruiting

Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants (ZnVeryPT)

Zinc Deficiency | Very Preterm Infants

Thailand
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study of Longer Interval of IVT IBI302 in Subjects With nAMD

Neovascular Age-related Macular Degeneration

China
Asarina Pharma
Scandinavian CRO

Completed

A Study Investigating the Efficacy and Safety of Sepranolone in Women With Menstrual Migraine (APH204)

Menstrual Migraine

Finland, Sweden
Mitotech, SA
ORA, Inc.

Completed

A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES)

Keratoconjunctivitis Sicca

United States
Sanofi Pasteur, a Sanofi Company

Completed

A Study of High-Dose Trivalent Inactivated Influenza Vaccine in Adults 50 to 64 Years of Age

Influenza

United States
Sanofi

Terminated

Multi-Year Study of Fluzone High-Dose Influenza Vaccine Compared With Fluzone® Vaccine in Adults Aged 65 Years and Older

Influenza

United States, Puerto Rico
University of Giessen
Novartis; Astellas Pharma US, Inc.; German Cancer Research Center; Heidelberg University

Completed

Impact of Rituximab (RTx) Induction and Living Donation on Immunoregulation and Virus Control in Renal Transplantation

Kidney Transplantation | Immunology | Virus | Living Donors | Rituximab (RTx)

Germany
Weill Medical College of Cornell University

Active, not recruiting

PRE-ProstAtectomy MRI-GuidEd Stereotactic Body RadioTherapy for High-Risk Prostate Cancer Trial (PREPARE SBRT) (PREPARE SBRT)

Prostate Cancer

United States
Brown University
Rhode Island Hospital; Memorial Hospital of Rhode Island; Lifespan

Completed

BrUOG 278: FOLFOX-A For Pancreatic Cancer A Brown University Oncology Research Group Study (278)

Metastatic Pancreatic Cancer

United States
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Completed

The Safety, Tolerability and Pharmacokinetic Study of ZSP1273 in Healthy Volunteers.

Influenza

China
Boehringer Ingelheim

Completed

Efficacy and Safety of Lacidipine in Chronic Stable Angina

Angina Pectoris
University Hospital, Basel, Switzerland
Odense University Hospital; Royal Marsden NHS Foundation Trust; UMC Utrecht

Recruiting

Management of Immune Checkpoint Inhibition-related Hepatitis Using Low-dose Corticosteroids (MIRA-HEP)

Cancer | Immune-Mediated Hepatitis | Immune Related Adverse Events

United Kingdom, Switzerland
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Hunan Cancer... and other collaborators

Recruiting

Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy

Nasopharyngeal Carcinoma | De-escalation Therapy

China
Blue Lake Biotechnology Inc.

Recruiting

A Study of BLB-201 RSV Vaccine in Infants and Children

Respiratory Syncytial Virus Infections

United States
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Completed

Clinical Trial of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)

Acute Gastroenteritis

China
PHARMENTERPRISES LLC

Completed

Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.

Healthy Volunteers

Russian Federation
Medicines for Malaria Venture
University of Cape Town

Terminated

Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers

Malaria

South Africa
Agios Pharmaceuticals, Inc.

Completed

A Phase I Study of AG-348 in Healthy Volunteers (AG-348 SAD)

Healthy Volunteer

United States
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Endothelial Modulation for Angiogenic Therapy

Coronary Artery Disease

Canada
M.D. Anderson Cancer Center
Genzyme, a Sanofi Company

Terminated

Thymoglobulin (ATG) Dose Finding Study

Graft vs Host Disease

United States
Laboratorios Silanes S.A. de C.V.

Completed

Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers (NTC00940472)

Healthy

Spain
Centre Hospitalier Arras

Completed

Under the Nose Face Mask to Prevent Facial Pressure Ulcers During NIV for Acute Hypercapnic Respiratory Failure (AHRF) (UNDER PRESSURE)

Acute Hypercapnic Respiratory Failure

France
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG1205

Healthy

Belgium
Chen Lizhu

Not yet recruiting

Ipilimumab (N01) Plus Sintilimab and Modified XELOX as Conversion Therapy in Unresectable Locally Advanced Gastric Cancer (DIAMC-GC)

Locally Advanced Gastric Cancer
Zhongnan Hospital

Recruiting

High - Dose Vitamin C Infusion Regimen Based on Pharmacokinetic Characteristics for Patients With Advanced Malignant Solid Tumors

Vitamin C

China
Hansoh BioMedical R&D Company

Recruiting

A Study of HS-20124 in Patients with Advanced Solid Tumors

Solid Cancer

China
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer Patients

Metastatic Pancreatic Cancer

Singapore
Mahatma Gandhi Institute of Medical Sciences

Recruiting

Low-Dose Radiation Therapy to Lungs in Moderate COVID-19 Pneumonitis: A Case-Control Pilot Study (LOCORAD)

COVID-19 | Pneumonia

India
Stanford University

Completed

High Dose Chemotherapy and Autologous Transplant for Breast Cancer

Graft vs Host Disease

United States
Genexine, Inc.

Completed

Safety and Immunogenicity Study of GX-19N, a COVID-19 Preventive DNA Vaccine in Healthy Adults

SARS-CoV-2

Korea, Republic of
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR); McGill University Health Centre... and other collaborators

Active, not recruiting

Enteral High-dose DHA Supplementation on Bronchopulmonary Dysplasia in Very Preterm Infants: a Collaborative Study

Child Development | Bronchopulmonary Dysplasia | Neonatal and Perinatal Conditions

Canada
Radionetics Oncology

Terminated

Phase 1 Study of 68Ga-R8760

Adrenocortical Carcinoma

United States

Search clinical trials for: Dose decrease

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