Search clinical trials for: Dose decrease

Total 7790 results

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Baylor College of Medicine
Center for Cell and Gene Therapy, Baylor College of Medicine

Completed

A Phase I/II Study Of Immunization With Lymphotactin And Interleukin 2 Gene Modified Neuroblastoma Tumor Cells (CHESAT)

Neuroblastoma

United States
JDP Therapeutics, Inc.
Algorithme Pharma Inc

Completed

Safety, Tolerability and Pharmacokinetics Trial of JDP-205 Injection 10 mg

Acute Urticaria

Canada
Actavis Inc.

Completed

Bioequivalence Study of Galantamine 4 mg Tablet and Reminyl Following a 4 mg Dose in Healthy Subjects Under Fasting Conditions

Healthy

Canada
University of Vermont
World Health Organization

Active, not recruiting

Intradermal Fractional Dose IPV (fIPV) in Combination With dmLT

Poliomyelitis

United States
University Hospital, Angers

Completed

Sildenafil Efficacy Study on Time Walk From Peripheral Arterial Desease Patients (Stade II) With Arterial Claudication (ARTERIOFIL)

Peripheral Arterial Occlusive Disease
Yale University

Completed

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

Nicotine Dependence, Other Tobacco Product

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Effects of Once and Twice Daily Dosing Regimen of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-040)

Diabetes Mellitus, Type 2 | Adult
Menoufia University

Completed

Dosage of Intrathecal Hyperbaric Bupivacaine and the Incidence of Post Spinal Shivering.

Cesarean Section; Shivering

Egypt
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Modafinil Treatment for Cocaine-Dependent Individuals

Cocaine-Related Disorders

United States
Boehringer Ingelheim
Pfizer

Completed

Efficacy and Safety of 2 Doses of Tiotropium Respimat Compared to Placebo in Adolescents With Severe Persistent Asthma

Asthma

United States, Argentina, Australia, Bulgaria, Germany, Guatemala, Hungary, Israel, Latvia, Mexico, Philippines, Portugal, South Africa, Ukraine
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Effectiveness and Safety of Two Doses of Risperidone in the Treatment of Children and Adolescents With Autistic Disorder

Autistic Disorder | Autism

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Cetirizine HCl 10 mg Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Sertraline HCl 100 mg Tablets Under Non-fasting Conditions

Healthy

United States
University of Vigo
Novartis; Hospital Clinico Universitario de Santiago

Completed

Comparison of the Antihypertensive Efficacy of Valsartan and Enalapril After Missing One Dose

Hypertension

Spain
Aswan University Hospital

Not yet recruiting

Effects of Neostigmine-dose on Diaphragmatic Dynamics (DTF/DE/AChE)

Diaphragm Ultrasound
Eclipse Life Sciences, Inc.

Recruiting

EC-104 Intravitreal Implant for the Treatment of Diabetic Macular Edema (BETTIS-1)

Diabetic Macular Edema

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Clinical Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

Bladder Cancer

China
Korea University Anam Hospital

Recruiting

A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke

Dyslipidemias | Stroke, Acute Ischemic

Korea, Republic of
Ottawa Hospital Research Institute

Recruiting

PDA Treatment With Ibuprofen and Changes in Tissue Oxygenation.

Patent Ductus Arteriosus After Premature Birth

Canada
Mayo Clinic
National Cancer Institute (NCI)

Completed

Hypofractionated Radiation Therapy for Treating Prostate Cancer High-Risk Features Following Radical Prostatectomy

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer AJCC v8

United States
The University of Texas Medical Branch, Galveston

Completed

Low-Dose Versus High-Dose Oxytocin Dosing for Induction and Augmentation of Labor

Labor Long

United States
Ekim Seven

Completed

Effect of Nicotine Pouches on The Underlying Normal Electrocardiogram (NICOTUNE)

Heart Rate | Vital Sign Monitoring | Symptoms | ECG

Denmark
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Japanese Adults 60 Years of Age and Older

Healthy Volunteers | Influenza Immunization

Japan
University Hospital Regensburg
Celgene; Anticancer Fund, Belgium

Terminated

Low-dose AZA, Pioglitazone, ATRA Versus Standard-dose AZA in Patients >=60 Years With Refractory AML (AML-ViVA)

Acute Myeloid Leukemia

Germany
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
ETOP IBCSG Partners Foundation
Breast International Group

Completed

Palbociclib in Molecularly Characterized ER-positive/HER2-negative Metastatic Breast Cancer (PYTHIA)

Metastatic Breast Cancer

United Kingdom, Belgium, Italy
Helwan University

Active, not recruiting

The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients

Post Operative Atrial Fibrillation

Egypt
Eli Lilly and Company
Alkermes, Inc.

Completed

Compare Two Dosing Algorithms in Insulin-Naive Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Puerto Rico, United States, Spain, India, Belgium, Argentina, Austria, France, Mexico
Kobe University

Completed

Effect of Rosuvastatin and Eicosapentaenoic Acid on Neoatherosclerosis: The LINK-IT Trial

Coronary Artery Disease Progression
Boehringer Ingelheim

Completed

Pharmacokinetic Properties of Nevirapine Extended Release Tablets When Administered Orally in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /Metformin

Healthy

China
Lexicon Pharmaceuticals

Completed

Study of LX4211 in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Irrua Specialist Teaching Hospital
University of Bordeaux; Médecins Sans Frontières, Belgium; ANRS, Emerging Infectious... and other collaborators

Recruiting

ISTH/ANRS 0409s INTEGRATE Lassa Fever Study

Lassa Fever

Liberia, Nigeria
Lykos Therapeutics

Completed

Randomized, Double-blind, Placebo-Controlled Pilot Study of MDMA-assisted Therapy for PTSD

Posttraumatic Stress Disorder (PTSD)

Israel
Universidad Peruana Cayetano Heredia
Oxfendazole Development Group

Not yet recruiting

Oxfendazole in Mild Parenchymal Brain Cysticercosis

Brain Cysticercosis
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1

HIV

United States, South Africa, Thailand
Vigonvita Life Sciences

Recruiting

Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LV232 Capsules in the Treatment of MDD

MDD

China
WestVac Biopharma Co., Ltd.

Not yet recruiting

A Phase Ⅲ Clinical Trial of Recombinant COVID-19 Trivalent (XBB+BA.5+Delta) Protein Vaccine (Sf9 Cell) in Booster Vaccination

COVID-19
Poznan University of Medical Sciences

Completed

Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery

Hand Injuries and Disorders | Wrist Disease

Poland
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Completed

A Phase Ib Study of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)

Tuberculosis

China
Cerevel Therapeutics, LLC

Completed

A Trial of the Effect of CVL-865 on Panic Symptoms Induced by Carbon Dioxide Inhalation in Healthy Subjects

Panic Disorder

Netherlands
Columbia University

Completed

Study of the Effect of Intradialytic Vasopressin on Chronic Hypertension in Patients With End Stage Renal Disease

Hypertension | End Stage Renal Disease

United States
GlaxoSmithKline

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Intravenous Infusion of GW328267X in Healthy Volunteers

Lung Injury, Acute

United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

Study of Fluzone® Quadrivalent, Fluzone® Intradermal, and Fluzone® High-Dose, Influenza Vaccines in Adults

Influenza

United States
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Centre national de recherche et de formation...

Completed

Low Dose Primaquine for Clearance of Gametocytes (LOPRIM)

Malaria | Plasmodium Falciparum | Asymptomatic Malaria

Burkina Faso
Merck Sharp & Dohme LLC

Completed

Biomarkers of Muscle Anabolism (MK-0000-082)

Muscle Anabolism
Boehringer Ingelheim

Completed

Study to Assess the Safety of Ipratropium Bromide, in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Actavis Inc.

Completed

Bioequivalence Study of Galantamine 4 mg Tablet and Reminyl Following a 4 mg Dose in Healthy Subjects Under Fed Conditions

Healthy

Canada
Actavis Inc.

Completed

A Relative Bioavailability Study of Sertraline HCl 100 mg Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Finasteride 5 mg Tablets Under Fasting Conditions

Healthy

Canada

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