Search clinical trials for: Dose decrease

Total 7790 results

Brown University
The Miriam Hospital; Rhode Island Hospital

Terminated

First-Line FOLFOX-Bevacizumab for Advanced Colorectal Cancer With Wild-Type Ras

Colorectal Cancer

United States
Akebia Therapeutics

Completed

Effect of AKB-6548 on Cardiac Repolarization Intervals in Healthy Volunteers

Healthy Volunteers

United States
University Hospital, Antwerp

Completed

Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex (SUDIA)

Muscle Weakness | Muscle Fatigue | Diaphragmatic Dysfunction

Belgium
Tianjin Ever Union Biotechnology Co., Ltd.

Unknown

Safety and Efficacy of UC-MSCs in Patients With Plaque Psoriasis

Moderate and Severe Plaque Psoriasis

China
Boehringer Ingelheim

Completed

Telmisartan80/HCTZ25 Versus Telmisartan80/HCTZ12.5 in Hypertension Not Responding to Telmisartan80/HCTZ12.5

Hypertension

France, Switzerland, Italy, Germany, Hong Kong, Netherlands, South Africa, Spain, Taiwan, Denmark, Sweden, Finland, Ireland, Korea, Republic of, Malaysia, Norway
Biogen

Terminated

Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects

Neuropathic Pain | Pain, Neuropathic
e-Therapeutics PLC

Completed

Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD) (ETS6103-003)

Major Depressive Disorder

United Kingdom
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Severe Active Rheumatoid Arthritis, Comparing Tapering Versus Maintaining the Methotrexate Dosage

Rheumatoid Arthritis

United Kingdom
Seoul National University Hospital

Completed

Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen

Pain, Postoperative | Hyperalgesia | Remifentanil | Ibuprofen

Korea, Republic of
Sanofi Pasteur, a Sanofi Company

Completed

Study of Fluzone® Influenza Virus Vaccines 2012-2013 Formulation Among Adults.

Influenza

United States
Iroko Pharmaceuticals, LLC

Completed

Study of Diclofenac Capsules to Treat Dental Pain

Dental Pain

United States
Jonsson Comprehensive Cancer Center

Recruiting

Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

Prostate Adenocarcinoma | Stage II Prostate Cancer AJCC v8 | Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8

United States
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants

Diarrhoea

Kenya
AstraZeneca

Completed

Study to Assess the Bioavailability of Ticagrelor OD Tablet vs. IR Tablet

Healthy Subjects | Bioavailability

Germany
HIV Prevention Trials Network
Gilead Sciences

Completed

Pre-Exposure Prophylaxis for Transgender Women in the US and South America

HIV Prevention

United States, Brazil
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

Evaluation of the Efficacy and Safety of Megestrol Acetate in Preventing Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy

Efficacy | Safety | Megestrol Acetate | Adult Subject

China
Stanford University
Washington University School of Medicine; Duke University; University of Washington and other collaborators

Enrolling by invitation

Antibiotic Prophylaxis in Rhinoplasty

Nasal Obstruction | Nasal Surgical Procedures

United States
Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Tang-Du Hospital

Unknown

The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia

Spinal Diseases | Local Anesthesia
Boehringer Ingelheim

Completed

Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male and Female Volunteers

Healthy
Far Eastern Memorial Hospital
Research Ethics Review Committee

Unknown

Comparing Treatment Efficacy With High and Medium Dose of Fluticasone in Combination With Salmeterol in COPD Patients

Quality of Life | Percentage of Annual Acute Exacerbation

Taiwan
DICE Therapeutics, Inc., a wholly owned subsidiary...

Completed

A Drug-drug Interaction Study Evaluating the Perpetrator Potential of LY4100511 (DC-853) on Midazolam, Repaglinide, Digoxin, Rosuvastatin in Healthy Participants

Healthy

United States
Stanford University

Completed

Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management

Postoperative Pain

United States
Guangdong Hengqin Novagains Biopharmaceutical Co...
Xiangbei Welman Pharmaceutical Co., Ltd; Guangzhou Xin-Chuangyi Biopharmaceutical...

Enrolling by invitation

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral F-02-2-Na Tablets in Adult Subjects

Hyperuricemia With or Without Gout

China
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

Metastatic Melanoma | Metastasis to Brain

United States
AbbVie

Terminated

Study of BOTOX Injections in Prevention of Migraine in Adult Participants With Episodic Migraine

Episodic Migraine

United States, Canada, Czechia, Germany, Poland, Spain, Sweden, United Kingdom, Israel
AbbVie

Completed

A Study to Evaluate Participant Satisfaction and Natural Outcomes Following Administration of BOTOX Cosmetic Injections in Adult Participants for Treatment of Upper Facial Lines (UFL BOND 974)

Upper Facial Lines

United States, Canada
National Cancer Institute (NCI)

Completed

Primary Chemotherapy With Docetaxel-Capecitabine and Doxorubicin-Cyclophosphamide in Breast Cancer

Breast Cancer | Breast Neoplasm

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Evaluation of the Efficacy of Corticosteroids in Septic Arthritis in Adults (CORSAR)

Septic Arthritis

France
People's Hospital of Guangxi
Liuzhou Workers Hospital; Cancer Hospital of Guangxi Medical University; First... and other collaborators

Not yet recruiting

Addition of Anlotinib Hydrochloride to the Stupp Regimen Versus the Stupp Regimen Alone for Newly Diagnosed Glioblastoma

Glioblastoma

China
University Hospital, Antwerp

Active, not recruiting

Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients (ADDIT-GLIO)

Glioblastoma Multiforme of Brain

Belgium
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin

Completed

Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children (OPTIBAYE)

Methicillin-resistant Staphylococcal Infections

France
Mayo Clinic

Completed

Intralipid Versus SMOFlipid in HPN Patients

Crohn Disease | Intestinal Fistula | Intestinal Obstruction | Short Bowel Syndrome

United States
Air Liquide Santé International

Completed

Evaluation of Satisfaction Regarding Home Healthcare Provider (HHP) Management of Type 1 Diabetic Patients Using a Closed-loop Automatic Insulin Delivery System (SATURN)

Diabetes type1

France
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Active, not recruiting

A Study to Evaluate Safety and Efficacy of HS-10296 as First-Line Treatment in Patients

Non Small Cell Lung Cancer

China
National Cardiovascular Center Harapan Kita Hospital...

Unknown

Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass

Cardiopulmonary Bypass | Congenital Heart Disease | Thiamine Deficiency

Indonesia
Seattle Children's Hospital
Children's Healthcare of Atlanta; Pediatric Oncology Experimental Therapeutics...

Completed

POETIC Plerixafor as a Chemosensitizing Agent for Relapsed Acute Leukemia and MDS in Pediatric Patients

AML | Acute Leukemia of Ambiguous Lineage | ALL | Relapsed/Refractory AML | Relapsed/Refractory ALL | Secondary AML/MDS

United States, Canada
European Institute of Oncology

Completed

Prevention of Chemotherapy-induced Cardiotoxicity in High-risk Patients

Cardiotoxicity | Chemotherapeutic Toxicity

Italy
Universitaire Ziekenhuizen KU Leuven
Allergan

Unknown

Investigation of IOP and Tolerability of Bimatoprost 0.01% and Tafluprost Unit Dose Preservative Free 15 Microgram/ml (SPORTII)

Ocular Hypertension | Glaucoma

Belgium, Austria, Italy, Switzerland, United Kingdom
Medical Research Council

Completed

Vitamin D Half-life in Pregnancy and Lactation

Pregnancy | Lactation
Boehringer Ingelheim

Completed

Safety and Tolerability of 4 Different Dosage Strengths of BIBW 2992 Tablets to Healthy Male Volunteers

Healthy
Inje University

Withdrawn

Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERD (DRNERD)

Gastroesophageal Reflux Disease

Korea, Republic of
University of Arkansas

Completed

UARK 2003-41: A Study of High-Dose Density Therapy in Patients With Multiple Myeloma

Multiple Myeloma

United States
University Hospital, Ghent
Fund for Scientific Research, Flanders, Belgium

Completed

Psychosocial and Physiological Mechanisms in the Effect of Hormonal Contraception on the Female Sexual Desire

Healthy

Belgium
Peking University People's Hospital

Not yet recruiting

Optimal Dose of Zanubrutinib to Treat Adult Immune Thrombocytopenia

Immune Thrombocytopenia
Namik Kemal University

Not yet recruiting

Evaluation of Geriatric Questionnaires to Predict Toxicities of CDK 4/6 Inhibitors in Older Breast Cancer Patients?

Can the Geriatric Questionnaires Predict Adverse Effects in Geriatric Breast Cancer Patients Treated With Cyclin-dependent Kinase 4 and 6 Inhibitors

Turkey
Northwestern University
Mayo Clinic

Recruiting

Optimizing Y90 Therapy for Radiation Lobectomy

HCC | Metastatic Cancer | Transplant | Adult Primary Liver Cancer | Resection

United States
AstraZeneca

Completed

Phase II Single Arm Study of AZD9291 to Treat NSCLC Patients in Asia Pacific (AURA17)

Non-Small Cell Lung Cancer

China, Australia, South Korea
University of Nebraska
Bristol-Myers Squibb

Completed

Dasatinib in Relapsed or Refractory Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United States
Merck Sharp & Dohme LLC

Completed

Evaluation of the Safety and Immunogenicity of Three Consistency Lots and a High-Dose Lot of rVSV-ZEBOV-GP (V920 Ebola Vaccine) in Healthy Adults (V920-012)

Prevention of Ebola Infection

Search clinical trials for: Dose decrease

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