Search clinical trials for: FixedO2

Total 859 results

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University of California, Davis

Completed

Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART

Human Immunodeficiency Virus Infection

United States
Janssen Research & Development, LLC

Completed

Fluoroquinolone Associated Disability

Sinusitis | Urinary Tract Infections | Bronchitis

United States
M.D. Anderson Cancer Center

Withdrawn

IPI-Biotherapy for Patients Previously Treated With Cytotoxic Drugs With Metastatic Melanoma

Melanoma
Sanofi

Active, not recruiting

A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (IZALCO)

Relapsed/Refractory Multiple Myeloma

Australia, Czechia, Portugal, China, Brazil, Greece, Japan
Dizal Pharmaceuticals

Completed

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients with EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Non-small Cell Lung Cancer

China
Chiesi Farmaceutici S.p.A.

Completed

Lung Bioavailability and Total Systemic Exposure to Beclomethasone17MonoPropionate and Formoterol Across Two Strengths of NEXThaler Inhalation Powder

Asthmatic

United Kingdom
Yonsei University

Completed

Clinical Study to Evaluate Adherence Improvement Fixed-dose Combination of Olostar Tab. in Patients With Hypertension and Dyslipidemia

Hypertension | Dyslipidemias

Korea, Republic of
Allergan

Completed

Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan®

Ocular Hypertension | Glaucoma

United States
University of Alabama at Birmingham
Bristol-Myers Squibb

Completed

The Bioequivalence of Atripla in an Oral Liquid Formulation Compared With the Tablet Formulation in Healthy Volunteers

Healthy

United States
Semmelweis University

Recruiting

The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation

Alveolar Bone Loss | Edentulism Nos

Hungary
Laboratorios Silanes S.A. de C.V.

Completed

Non-interaction Study Between Pregabalin and Tramadol, Administered Individually or Combination, in Healthy Subjects

Healthy

Mexico
Laboratorios Silanes S.A. de C.V.

Completed

Pharmacokinetic Interaction Between Ibuprofen and Acetaminophen Oral Suspension

Healthy

Mexico
ANRS, Emerging Infectious Diseases
NEAT - European AIDS Treatment Network

Completed

Study of Darunavir/r + Tenofovir/Emtricitabine vs. Darunavir/r + Raltegravir in HIV-infected Antiretroviral naïve Subjects (ANRS 143)

HIV Infections

Ireland, United Kingdom, Netherlands, France, Spain, Greece, Belgium, Germany, Denmark, Sweden, Italy, Portugal, Austria, Hungary, Poland
Chong Kun Dang Pharmaceutical
Inje University

Completed

Comparative Pharmacokinetics Study of Clopidogrel and Aspirin Fixed-dose Combination Versus Separate Combination-2nd Trial

Coronary Artery Disease

Korea, Republic of
BeOne Medicines

Recruiting

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors (CaDAnCe-303)

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

China, Taiwan
GlaxoSmithKline

Completed

Observed Outcomes Associated With Fluticasone Propionate/Salmeterol Xinafoate or Inhaled Corticosteroids in Asthma Patients

Asthma
Allergan

Completed

Safety and Efficacy of Olopatadine Hydrochloride/Ketorolac Tromethamine Ophthalmic Solution Compared With Olopatadine Hydrochloride Ophthalmic Solution in Patients With Seasonal Allergic Conjunctivitis

Rhinitis, Allergic, Seasonal | Conjunctivitis, Allergic

India
Janssen Sciences Ireland UC

Completed

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Healthy

Netherlands
Ferrer Internacional S.A.

Terminated

A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Low Density Lipoprotein (LDL) Cholesterol

Elevated LDL Cholesterol

United States
NeuroRx, Inc.

Not yet recruiting

NRX-101 for Complicated Urinary Tract Infection (UTI) Including Pyelonephritis

Urinary Tract Infections | Pyelonephritis
Blokhin's Russian Cancer Research Center

Recruiting

Analysis of Therapy Sequence in Women With HR+, HER2 - mBC in Moscow: A Multicenter Retrospective Observational Study.

Breast Cancer Stage IV

Russian Federation
Beijing Dongfang Biotech Co., Ltd.

Completed

Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects

Diabetes Mellitus, Type 2 | Overweight

China
Bayer

Completed

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
Hamdard University

Recruiting

To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome

Metabolic Syndrome

Pakistan
Hoffmann-La Roche
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants (POSTERITY)

Lupus Nephritis

United States, Mexico, Canada, Spain, United Kingdom, France, Italy, Peru, Brazil, Poland, South Africa, Russia
Sanofi

Completed

Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period (LixiLan-G)

Type 2 Diabetes Mellitus

Estonia, Italy, Israel, United States, Canada, Germany, Romania, Slovakia, Spain
Chiesi Farmaceutici S.p.A.

Completed

Clinical Pharmacology Study of CHF1535 pMDI 50/6 µg Versus The Free Combination In Asthmatic Children 5-11 Years Old (PAED1)

Asthma

Denmark
Ferrer Internacional S.A.

Terminated

Pharmacodynamic Clinical Trial of Cardiovascular Polypill on LDL Cholesterol

Elevated LDL Cholesterol

Spain
Centre Hospitalier Universitaire Vaudois
AstraZeneca

Completed

Platelet Inhibition After Pre-hospital Ticagrelor Using Fentanyl Compared to Morphine in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention (PERSEUS)

Acute Myocardial Infarction

Switzerland
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
Ain Shams University

Not yet recruiting

A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG

Coronary Artery Disease | Systemic Inflammatory Response Syndrome | Postoperative Complications

Egypt
National Cancer Institute (NCI)

Completed

Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy

Prostate Cancer | Neoplasms of Prostate | Cancer Of Prostate | Prostate Neoplasms | Prostatic Cancer

United States
Janssen-Cilag G.m.b.H

Completed

Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) With Darunavir/Ritonavir (DRV/r) (PEPDar)

Human Immunodeficiency Virus (HIV)

Germany
Abbisko Therapeutics Co, Ltd

Completed

A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021

Healthy Subjects

China
Neutec Ar-Ge San ve Tic A.Ş

Withdrawn

Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD

Chronic Obstructive Pulmonary Disease
David Bartlett
National Cancer Institute (NCI)

Completed

αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies

Peritoneal Carcinomatosis | Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface | Malignant Peritoneal Mesothelioma

United States
Alexion Pharmaceuticals, Inc.

Completed

A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults

Healthy

United Kingdom
Ache Laboratorios Farmaceuticos S.A.

Withdrawn

Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis

Inflammation | Cough | Rhinitis
Hoffmann-La Roche

Completed

A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (Ocarina II)

Relapsing Multiple Sclerosis | Primary Progressive Multiple Sclerosis

United States, Spain, Italy, Czechia, Poland, New Zealand, Turkey, Brazil
National Cancer Institute (NCI)
NRG Oncology; Radiation Therapy Oncology Group

Completed

Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

Adult Glioblastoma | Adult Gliosarcoma

United States
Hoffmann-La Roche

Completed

A Study to Evaluate Patient Preference for Home Administration of Fixed-Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Administration in Participants With Early or Locally Advanced/Inflammatory HER2-Positive Breast Cancer (ProHer)

Inflammatory Breast Cancer | Early Breast Cancer | Locally Advanced Breast Cancer

Canada, Spain, Croatia, Bosnia and Herzegovina, Costa Rica, Singapore, Bulgaria, South Africa, Kenya, Brazil, India, Chile, Peru, Argentina, South Korea, Turkey (Türkiye), Mexico
GlaxoSmithKline

Completed

Outcomes and Costs Associated With Initiating Maintenance Treatment With Fluticasone Propionate 250mcg/Salmeterol Xinafoate 50mcg Combination (FSC) Versus Anticholinergics Including Tiotropium (TIO) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Eli Lilly and Company

Completed

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Healthy | Overweight | Obese

United States
St George's, University of London
The Stroke Association, United Kingdom

Completed

To Determine the Feasibility of a Clinical Trial Comparing Anticoagulants Versus Antiplatelets in the Acute Treatment of Patients With Cervical Artery Dissection (CADISS)

Stroke | Cervical Artery Dissection | Vertebral Artery Dissection | Carotid Artery Dissection

United Kingdom
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

Locally Advanced or Metastatic Breast Cancer

United States, Spain, Taiwan, France, Argentina, Belgium, China, Germany, Saudi Arabia, Thailand, United Kingdom, Colombia, Poland, India, Portugal, Hungary, Mexico, Lebanon, Jordan, Kenya, Brazil, Italy, Oman, Egypt, South Korea, Turkey... and more
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

OX40, Venetoclax, Avelumab, Glasdegib, Gemtuzumab Ozogamicin, and Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States
University of Aarhus
Novartis; Danish Heart Foundation; Danish Cardiovascular Research Academy

Terminated

Effects of Intensive Long-Term Vasodilation in Hypertensive Patients With Microvascular Angina Pectoris

Hypertension | Microvascular Angina

Denmark
TASK Applied Science
Innovative Medicines Initiative

Recruiting

A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination with Ethionamide (ENABLE)

Tuberculosis

South Africa
University of Jena

Completed

Effectiveness of Dalteparin Therapy as Intervention in Recurrent Pregnancy Loss

Abortion, Habitual

Germany, Austria
Genentech, Inc.

Completed

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response (MyTACTIC)

Advanced Unresectable or Metastatic Solid Malignancy

United States

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