Search clinical trials for: HFO-RMs

Total 3768 results

AstraZeneca

Completed

Study to Assess Bronchospasm Potentially Induced by Next-Generation Propellant vs HFA Propellant in an MDI in Participants With Well/Partially Controlled Asthma

Asthma

United States
AstraZeneca

Completed

A Study to Assess the Safety of Budesonide/Glycopyrronium/Formoterol Fumarate With a Next-Generation Propellant in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada, Germany, Argentina, Bulgaria, Poland, Mexico, United Kingdom, Turkey (Türkiye)
University of Athens
University of Thessaly

Terminated

High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS)

Acute Respiratory Distress Syndrome

Greece
AstraZeneca
Parexel

Completed

A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) With a Next-Generation Propellant (NGP) With a Spacer, BGF MDI Hydrofluoroalkane (HFA) With a Spacer, as Well as BGF MDI NGP Without a Spacer

Chronic Obstructive Pulmonary Disease

Germany
AstraZeneca
Parexel

Withdrawn

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) With a Next-generation Propellant (NGP) With a Spacer, BGF MDI Hydrofluoroalkane (HFA) With a Spacer, as Well as BGF MDI NGP Without a Spacer

Healthy

Germany
University Hospital, Rouen

Recruiting

Non-invasive Ventilation and High-speed Oxygen Therapy Effects on Heart Function - HiFlow-Heart Study (HiFlow-Heart)

Chronic Heart Failure

France
AstraZeneca

Active, not recruiting

A Study to Investigate the Effect on Lung Function of BDA Formulated With a Next Generation Propellant Compared With an Approved Asthma Treatment (BDA With HFA Propellant) in Participants With Asthma

Asthma

United States, Thailand, Vietnam, China, Mexico, Malaysia
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul; Coordenação de Aperfeiçoamento de...

Completed

Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2 | Dietary Modification | Insulin Tolerance | Diabetic Blood Glucose Monitoring

Brazil
Istituti Clinici Scientifici Maugeri SpA
Fisher and Paykel Healthcare; Azienda Ospedaliera Ospedale Maggiore di Crema; University of Modena and Reggio Emilia and other collaborators

Completed

Effect of Exercise Training Under HFO Device on Endurance Tolerance in Patients With COPD and CRF: a Randomized Controlled Study. (HFO)

COPD

Italy
Bristol-Myers Squibb

Completed

Evaluate the Safety and Efficacy of 48-Hour Infusions of HNO (Nitroxyl) Donor in Hospitalized Patients With Heart Failure (STANDUP AHF)

Heart Failure

France, Germany, Japan, Spain, United States, Argentina, Poland, Italy, Czechia, Greece, Netherlands, Canada, United Kingdom
AstraZeneca

Completed

Study to Assess Effect of Next-Generation Propellant MDI on Mucociliary Clearance Vs. HFA Propellant MDI in Healthy Participants

Mucociliary Clearance

United States, United Kingdom
AstraZeneca

Completed

Study to Assess the Pharmacokinetic Bioequivalence of Budesonide and Albuterol With an Alternate Propellant Compared to Current Propellant.

Heathy Participants

United States
University of Zurich
Mayo Clinic; McGill University; University of Michigan; UMC Utrecht; University of... and other collaborators

Enrolling by invitation

Multicenter Comparison of Interictal HFO as a Predictor of Seizure Freedom (multiHFO)

Epilepsy Intractable

Switzerland
University of California, Los Angeles

Completed

High Frequency Oscillation in Pediatric Epilepsy Surgery (HFO)

Pediatric Epilepsy | Epilepsy Surgery | High Frequency Oscillation

United States
AstraZeneca

Completed

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a Next-Generation Propellant in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Canada, Thailand, Philippines, Vietnam, Argentina, Bulgaria, Hungary, Mexico, India, Malaysia, Poland, South Korea, Turkey (Türkiye)
King's College Hospital NHS Trust

Recruiting

Optimising HFO&VTV in Newborn Infants

High Frequency Oscillation | Volume Targeted Ventilation

United Kingdom
AstraZeneca
Parexel

Completed

Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI With Next-Generation Propellant Compared With BGF MDI With HFA Propellant

Chronic Obstructive Pulmonary Disease

United States
Trakya University

Completed

Efficacy of Different Respiratory Methods in Intensive Care

Respiratory Insufficiency

Turkey
Damascus University
Universiti Sains Malaysia

Completed

Treating Growing Patients With Mandibular Prognathism and Maxillary Constriction

Class III Malocclusion

Syrian Arab Republic
University Hospital, Toulouse

Completed

High Flow Oxygen VERSUS Non Invasive Ventilation Associated to Automated Flow Oxygen Titration After Patient Extubation (RespiFLOW)

Respiratory Disease

France
Damascus University
Universiti Sains Malaysia

Completed

Evaluation of Pain and Functional Impairments When Treating Class III Malocclusion Using Two Treatment Procedures

Class III Malocclusion | Maxillary Deficiency

Syrian Arab Republic
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Completed

Switching to Low Oxidant Content Cigarettes in Adult Smokers

Oxidative Stress | Nicotine

United States
Hospices Civils de Lyon

Recruiting

Effects of Non-invasive Ventilation Therapies on the Lung in Hypoxemic Chest Trauma Patients (VentiChest)

Lung Contusion | Lung Trauma

France
University of Athens
University of Thessaly

Completed

Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure (HFO-TGI-2)

Respiratory Distress Syndrome

Greece
Chulalongkorn University

Completed

Comparison Cytokine Clearance Between SLED-f Using High Cut-off Dialyzer and High-flux Dialyzer in Septic AKI Patients

Sepsis | Acute Kidney Injury
AstraZeneca
Parexel

Completed

A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI With Next-Generation Propellant Compared With BGF MDI With HFA Propellant

Chronic Obstructive Pulmonary Disease

United States
Bristol-Myers Squibb

Completed

A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function

Heart Failure | Cardiac Failure | Reduced Ventricular Ejection Fraction

United States, United Kingdom, Japan, Netherlands
University of Ljubljana
University of Ljubljana, Faculty of Medicine

Recruiting

Peripheral Magnetic Stimulation of Foot Muscles: Effects on Medial Longitudinal Arch Height and Foot Muscle Strength in Adults With Flat Feet (rPMS-Foot)

Flatfoot | Pes Planus | Posterior Tibial Tendon Dysfunction

Slovenia
Xingwang Zhu
Hunan Provincial People's Hospital; First People's Hospital of Chenzhou; Kunming... and other collaborators

Not yet recruiting

Combined Oscillation-Volume guarantEe Study

Bronchopulmonary Dysplasia (BPD) | Respiratory Distress Syndrome (& [Hyaline Membrane Disease])
Masarykova Nemocnice v Usti nad Labem, Krajska...

Not yet recruiting

Effect of High-Flow Nasal Oxygen on Laryngoscopic View

Difficult Airway | Laryngoscopy | Airway Complication of Anaesthesia | High Flow Nasal Canula | Airway Anesthesia | Difficult / Failed Intubation
National Cheng-Kung University Hospital

Completed

An Ankle-foot Orthosis Improves Gait Performance and Satisfaction in Stroke Patients

Gait Analysis

Taiwan
Kyowa Hakko Bio Co., Ltd.

Active, not recruiting

Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function

Gastrointestinal Diseases | Healthy

Singapore
Karolinska Institutet

Withdrawn

Postoperative Hyperbaric Oxygen Treatments to Reduce Complications in Diabetic Patients Undergoing Vascular Surgery (HODiVA)

Diabetes | Peripheral Arterial Disease | Arterial Occlusive Disease

Sweden
Vyaire Medical

Completed

Multicenter Study of the Safety and Performance of Fabian-PRICO for Saturation Targeting Routine Use in the NICU

Respiratory Insufficiency in Children

Netherlands, Poland
Texas Woman's University
Baylor Research Institute

Completed

Effects of Two Different Types of Ankle Foot Orthoses on Gait Outcomes in Patients With Subacute Stroke.

Stroke | Hemiplegia | Hemiparesis | Foot Drop | CVA

United States
University of Bath
University of Oxford; 3D Metal Printing Ltd; Versus Arthritis

Completed

Personalised Against Standard High Tibial Osteotomy (PASHiOn)

Medial Knee Osteoarthritis

United Kingdom
University Hospital, Tours

Recruiting

Weaning Protocol for High-flow Nasal Oxygen Therapy in Intensive Care (HiFloWEAN)

Acute Hypoxemic Respiratory Failure | High-flow Nasal Oxygen Therapy

France
HeartStitch.Com

Unknown

Stitch Closure of PFO and Septal Repair (STITCH)

Foramen Ovale, Patent | Septal Defect, Atrial | Septal Defect, Heart

United States
Hospices Civils de Lyon

Completed

Ventilation Strategies During Spontaneous Breathing Trial (WEANING)

Acute Respiratory Insufficiency

France
AstraZeneca
Parexel

Completed

A Study to Investigate the Exposure of Budesonide, Glycopyrronium, and Formoterol (BGF) Delivered by Hydrofluoroolefin (HFO) Propellant Metered Dose Inhaler (MDI) Compared to a Hydrofluoroalkane (HFA) Propellant MDI in Healthy Adults

Healthy Participants

United States
Mansoura University Children Hospital

Recruiting

Open-label Randomized Controlled Trial of Two Protocols for Weaning From High Frequency Oscillatory Ventilation in Preterm Neonates With Respiratory Distress Syndrome Admitted in the NICU of Mansoura University Children Hospital

Respiratory Distress Syndrome (Neonatal)

Egypt
Fort Belvoir Community Hospital
Walter Reed National Military Medical Center; US Army Night Vision and Electronic...

Completed

Optical Quality, Threshold Target Identification, and Military Target Task Performance After Advanced Keratorefractive Surgery

Myopia | Myopic Astigmatism

United States
Boehringer Ingelheim

Terminated

Comparison of Safety and Efficacy of COMBIVENT HFA to COMBIVENT (CFC) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Chiesi Farmaceutici S.p.A.

Recruiting

Therapeutic Equivalence of CHF5993 pMDI 100/6/12.5 µg HFA-152a in Subjects With Mild to Moderate Asthma (TRECONY)

Asthma

United Kingdom
Insel Gruppe AG, University Hospital Bern

Completed

High-fat Diet (HFD) and Small Intestinal Microbiome (FATBOM)

Microbial Colonization | Small Intestinal Bacterial Overgrowth

Switzerland
Ankara University
Saglik Bilimleri Universitesi Gulhane Tip Fakultesi; Gazi University; Zeynep... and other collaborators

Unknown

Rescue High Frequency Oscillatory Ventilation in Newborns Who Do Not Respond to Conventional Ventilation (RescueHFO)

Acute Mechanical Ventilatory Failure

Turkey
Lawson Health Research Institute
London Health Sciences Centre; St. Joseph's Health Care London; The W. Garfield...

Recruiting

Prebiotic Therapy to Improve Outcomes of Renal Transplant

Kidney Transplant; Complications

Canada
Sheba Medical Center

Completed

HF2 Therapy in the Treatment of Active Ulcerative Colitis

Ulcerative Colitis

Israel, Greece
RenJi Hospital

Not yet recruiting

Hemodiafiltration With Endogenous Reinfusion on Uremic Toxins Clearance of Maintenance Hemodialysis Patients

To Evaluate the Clearance Rate of Uremic Toxin by HFR
University of Texas Southwestern Medical Center

Terminated

Effectiveness of Ankle Foot Orthoses on Gait in Multiple Sclerosis

Multiple Sclerosis

United States

Search clinical trials for: HFO-RMs

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