Search clinical trials for: semustine

Total 104 results

Darell Bigner
Istari Oncology, Inc.

Not yet recruiting

Lerapolturev (PVSRIPO) in GBM

Recurrent Supratentorial Glioblastoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Lomustine in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Lung Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma

Brain Tumor | Central Nervous System Tumor

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
Novartis Pharmaceuticals

Completed

Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma Multiforme

United States, Belgium, Australia, Spain, France, Canada
Eli Lilly and Company

Completed

Enzastaurin Versus Lomustine in Glioblastoma

Glioblastoma

Germany, Italy, United States, Belgium, Netherlands, India, Austria, Spain, Poland, Australia, France, Mexico, United Kingdom, Canada
CNS Pharmaceuticals, Inc.
Worldwide Clinical Trials

Active, not recruiting

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme, Adult

United States, Spain, France, Switzerland, Italy
Incheon St.Mary's Hospital
National Cancer Center, Korea

Unknown

Procarbazine and Lomustine in Recurrent Glioblastoma

Recurrent Glioblastoma Multiforme

Korea, Republic of
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Chemotherapy, Filgrastim, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Lymphoma

United States
Pfizer

Completed

Study of IV Edotecarin Vs Temozolomide or Carmustine (BCNU) or Lomustine (CCNU) in Patients With Glioblastoma Multiforme

Glioblastoma

South Africa, Italy, Russian Federation, United States, Canada, Germany, Australia, Austria, Croatia, Czech Republic, France, India, Spain
University Hospital, Bonn

Completed

Efficacy and Safety Study of Lomustine/Temozolomide Combination Therapy vs. Standard Therapy for Glioblastoma Patients (CeTeG)

Glioblastoma

Germany
AstraZeneca

Completed

Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma (REGAL)

Recurrent Glioblastoma

United States, Australia, France, United Kingdom, Germany, Netherlands, Canada, Austria, Belgium, Czech Republic
University Hospital Heidelberg
Ruhr University of Bochum; Universitätsmedizin Mannheim

Recruiting

A Clinical Study to Improve Brain Function and Quality of Life of Patients With Newly Diagnosed Brain Tumors (Gliomas). (ImproveCodel)

Oligodendroglioma

Germany
NSABP Foundation Inc
National Cancer Institute (NCI)

Completed

Fluorouracil, Semustine, and Vincristine Compared With BCG in Treating Patients With Dukes' B or Dukes' C Colon Cancer That Has Been Removed By Surgery

Colorectal Cancer
Bart Neyns
Pfizer

Completed

A Randomized Phase II Clinical Trial on the Efficacy of Axitinib as a Monotherapy or in Combination With Lomustine for the Treatment of Patients With Recurrent Glioblastoma (AxiGII)

Glioblastoma Multiforme

Belgium
Hebei Yanda Hospital
Beijing Tiantan Hospital

Unknown

A Study to Evaluate the Safety and Effectiveness of PCV Chemotherapy in Patients With Recurrent High-grade Glioma With IDH1/2 Mutation

Recurrent High-grade Glioma

China
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644)

Glioblastoma | Astrocytoma
University of Leicester

Unknown

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

Brain and Central Nervous System Tumors

United Kingdom, Belgium, Germany, Netherlands, France, Sweden, Italy, Spain
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Metastatic Medulloblastoma Who Have Undergone Surgery

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors

Brain and Central Nervous System Tumors

United Kingdom, Ireland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Recurrent Glioblastoma | IDH Family Wildtype | Recurrent Anaplastic Astrocytoma

United States
European Organisation for Research and Treatment...
Medical Research Council

Completed

Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma

Brain and Central Nervous System Tumors

France, Switzerland, Netherlands, United Kingdom, Belgium, Germany, Italy, Sweden, Finland, Portugal, Austria, Hungary
French Innovative Leukemia Organisation

Completed

Lomustine and Intermediate Dose Cytarabine in Older Patients With AML

Acute Myeloid Leukemia

France
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; Eastern Cooperative Oncology Group and other collaborators

Completed

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors
Radiation Therapy Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma

Brain and Central Nervous System Tumors

United States
Institute of Cancer Research, United Kingdom

Completed

Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma

Brain and Central Nervous System Tumors

United States
DelMar Pharmaceuticals, Inc.

Terminated

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM (STAR-3)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM

United States
European Organisation for Research and Treatment...
Amgen

Withdrawn

Phase II Trial of Romiplostim for Thrombocytopenia Induced by Lomustine at First Progression of MGMT Promoter-meth Glioblastoma (RIGOLETTO)

First Progression of MGMT Promoter-methylated Glioblastoma

Spain, Switzerland
European Organisation for Research and Treatment...

Recruiting

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study (LEGATO)

First Progression of Glioblastoma

Netherlands, Austria, Germany
Indiana University
Indiana University Melvin and Bren Simon Cancer Center

Completed

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Brain and Central Nervous System Tumors | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
Proximagen, LLC

Terminated

Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)

Solid Tumors (Phase 1) | Relapsed/Recurrent GBM (Phase 2)

United States, Spain
Eli Lilly and Company

Active, not recruiting

A Dose-Escalation Study in Participants With Recurrent Malignant Glioma

Glioma

United States, Spain
Colorado Health Foundation

Unknown

Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas

Brain and Central Nervous System Tumors

United States, Canada
European Organisation for Research and Treatment...
Hoffmann-La Roche

Completed

Bevacizumab and Lomustine for Recurrent GBM

Cognition Disorders | Glioblastoma Multiforme | Disability Evaluation

Netherlands
Philogen S.p.A.

Not yet recruiting

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence (GLIOSTELLA)

Glioblastoma
University Hospital, Bordeaux

Completed

Adding Lomustine to Chemotherapy in Older Patients With Acute Myelogenous Leukemia (AML), and Allogeneic Transplantation for Patients From 60 to 65 Years Old (LAM-SA 2007)

Acute Myeloid Leukemia

France
Philogen S.p.A.

Recruiting

A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression (GLIOSTAR)

Glioblastoma

France, Germany, Italy, Switzerland
Philogen S.p.A.

Withdrawn

Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression (GLIOASTRA)

Glioblastoma
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma

Lymphoma

United States, Kenya, Uganda
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma

Intraocular Melanoma | Melanoma (Skin)

United States
Biodexa Pharmaceuticals

Active, not recruiting

A Study of Intra-tumoral Administered MTX110 in Patients With Recurrent Glioblastoma (MAGIC-G1)

Recurrent Glioblastoma

United States
Istituto Oncologico Veneto IRCCS
BAYER S.p.A. - Italia

Completed

Regorafenib in Relapsed Glioblastoma (REGOMA)

Glioblastoma Multiforme

Italy
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Study on the Efficacy and Safety of MA-BUCY2 Conditioning in High-risk AML Patients Underwent Haplo-HSCT

Conditioning | Haploidentical Stem Cell Transplantation

China
Karyopharm Therapeutics Inc

Terminated

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Glioblastoma Multiforme

United States, Canada
VBI Vaccines Inc.

Recruiting

Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects

Glioblastoma Multiforme

United States
Isarna Therapeutics GmbH

Completed

Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma

Glioblastoma | Anaplastic Astrocytoma

Germany, Austria, Georgia, India, Israel, Russian Federation
Sahlgrenska University Hospital, Sweden
Karolinska University Hospital; St. Olavs Hospital; University Hospital, Linkoeping and other collaborators

Completed

Disulfiram in Recurrent Glioblastoma

Glioma | Glioblastoma

Sweden, Norway
Isarna Therapeutics GmbH

Terminated

Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma (SAPPHIRE)

Glioblastoma | Anaplastic Astrocytoma

Spain, Taiwan, Korea, Republic of, United States, Hungary, Germany, Argentina, Brazil, India, Canada, Austria, France, Mexico, Poland, Russian Federation, United Kingdom
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Oral Combination Chemotherapy in Treating Elderly Patients With Intermediate or High-Grade Non-Hodgkin's Lymphomas

Lymphoma

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With AIDS-Related Hodgkin's Disease

Lymphoma

United States

Search clinical trials for: semustine

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