Search clinical trials for: decrease of sedation doses and switch of ventilator settings

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Ente Ospedaliero Ospedali Galliera

Not yet recruiting

Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery. (SAFE-AWARENESS)

Abdominal Surgery | Postoperative Cognitive Dysfunction (POCD) | Fraily

Italy
Tanta University

Recruiting

Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock

Hemorrhagic Shock | Norepinephrine | Hypotensive Resuscitation

Egypt
Brigham and Women's Hospital
POM Wonderful LLC

Active, not recruiting

Serial Brain MRI in Hospitalized Preterm Infants

Preterm Birth Complication

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE) (SAVE)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Hospices Civils de Lyon

Completed

MEK and Autophagy Inhibition in Metastatic/Locally Advanced, Unresectable Neuroblastoma RAS (NRAS) Melanoma (CHLOROTRAMMEL)

Metastatic NRAS Melanoma

France
Aswan University Hospital

Not yet recruiting

Effects of Neostigmine-dose on Diaphragmatic Dynamics (DTF/DE/AChE)

Diaphragm Ultrasound
HK inno.N Corporation

Unknown

Safety and Immunogenicity of CJ-40010 in Healthy Subjects

Hand, Foot and Mouth Disease

Korea, Republic of
Virchow Group
Adocia

Completed

Comparative Study of 3 Dose Regimens of BioChaperone to Becaplermin Gel for the Treatment of Diabetic Foot Ulcer

Diabetic Foot Ulcers

India
New Ismailia National University

Completed

Manual Hyperinflation and Physical Therapy Program on Lung Recruitment Mechanically Ventilated Pediatric Patients (MHI)

Physical Disability | Mechanical Ventilation Complication

Egypt
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Safety and Immune Response of an Investigational Vaccine for the Prevention of RSV (Respiratory Syncytial Virus) and (hMPV) Human Metapneumovirus Infection in Participants Aged 60 to 75 Years

RSV Infection | hMPV

Australia
The University of Hong Kong
United Christian Hospital

Completed

Pre-emptive Treatments in Lupus Nephritis Patients With Serological Reactivation

Lupus Nephritis

Hong Kong
Jiaxing AnDiCon Biotech Co.,Ltd

Completed

A Drug-Drug Interaction (DDI) Study of ADC189 With Itraconazole in Healthy, Adult Subjects

Healthy Adults

China
Centre Hospitalier Universitaire Dijon

Completed

Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular Carcinoma

Child-Pugh A Hepatocellular Carcinoma

France
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Respiratory Syncytial Virus/Human Metapneumovirus Vaccine Candidate

Healthy Volunteers | Respiratory Syncytial Virus Infection | Human Metapneumovirus

Puerto Rico, United States
GlaxoSmithKline

Completed

A Study to Evaluate Safety, Reactogenicity and Immunogenicity of GSK Biologicals' RSV Investigational Vaccine Based on Viral Proteins Encoded by Chimpanzee-derived Adenovector (ChAd155-RSV) (GSK3389245A) in RSV-seropositive Infants

Respiratory Syncytial Virus Infections

Taiwan, Spain, United States, Italy, Canada, Panama, Mexico, Poland
National Institute of Diabetes and Digestive and...
Prometheus Laboratories

Terminated

Imuran Dosing in Crohn's Disease Study

Crohn's Disease

United States, Canada
Yale University

Completed

Neuroimmune Effects of Opioid Administration (NOA)

Drug Effect

United States
European Society of Intensive Care Medicine

Completed

Strategy of UltraProtective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to seVere ARDS (SUPERNOVA)

Moderate Acute Respiratory Distress Syndrome

Belgium
Massachusetts General Hospital

Unknown

Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill

Obstructive Sleep Apnea | Critically Ill

United States
Hoffmann-La Roche

Completed

Open Label Ganciclovir Therapy for Sight- or Life-Threatening Cytomegalovirus Disease in the Immunocompromised Patient

HIV Infections | Cytomegalovirus Infections | Cytomegalovirus Retinitis

United States
Hoffmann-La Roche

Terminated

A 48 Week Study Comparing Treatment With Saquinavir + Lopinavir/Ritonavir in Combination With Enfuvirtide HAART Versus Saquinavir + Lopinavir/Ritonavir + Other Nucleoside Combinations to See the Efficacy of These Treatments in Patients Infected With HIV-1

HIV Infection

United States
Clinical Nutrition Research Centre, Singapore
Singapore Institute for Clinical Sciences

Completed

Insulin Modelling Based on Plasma Glucose Measures Via a Minimally-Invasive Glucose Sensor

PreDiabetes

Singapore
SK Bioscience Co., Ltd.
Coalition for Epidemic Preparedness Innovations

Completed

Safety and Immunogenicity Study of SARS-CoV-2 Nanoparticle Vaccine (GBP510) Adjuvanted With Aluminum Hydroxide (COVID-19)

COVID-19 (Healthy Volunteers)

Korea, Republic of
Istituto Romagnolo per lo Studio dei Tumori Dino...

Completed

Radiotherapy As an Immunological Booster in Patients with Metastatic Melanoma or Renal Cell Carcinoma Treated with High-dose Interleukin-2 (IL2HD)

Metastatic Renal Cell Cancer | Malignant Melanoma, Metastatic

Italy
University of Memphis
Unilever R&D

Completed

Safety and Tolerability of a Novel Amino-acid Based Hydration Drink in Healthy Volunteers

Tolerance | Safety

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Dupilumab for the Treatment of Chronic Inducible Cold Urticaria in Patients Who Remain Symptomatic Despite the Use of H1-antihistamine (LIBERTY-CINDU CUrIADS)

Cold Urticaria

United States, Argentina, Canada, Germany, Japan
Parc de Salut Mar

Completed

Generation of Biological Samples Positive to Triptorelin for Anti-doping Control (TRIPTO)

Healthy Volunteers

Spain
Boehringer Ingelheim

Completed

Efficacy and Safety of Lacidipine in Chronic Stable Angina

Angina Pectoris
Shanxi Medical University
Centers for Disease Control and Prevention, China

Completed

Immunogenicity of Hepatitis B Vaccination Among Drug Users

Hepatitis B Vaccination
Vanderbilt University
University of Pittsburgh; MCM Vaccines B.V.

Completed

Standard Dose Versus High-Dose Inactivated Flu Vaccine in Pediatric Solid Organ Transplant Patients

Pediatric Solid Organ Transplant Patients

United States
Saad Jamshed MD
Sanofi

Completed

Study Comparing High-Dose Flu Vaccine to Standard Vaccine in Cancer Patients Less Than 65 Receiving Chemotherapy (IMMUNE)

Cancer | Influenza Viral Infections

United States
American Heart Association

Completed

Improving Outcomes In Diabetic Patients During CABG Surgery By Optimizing Glycemic Control

Glycemic Control

United States
Biogen

Completed

Phase 1 Study to Evaluate the PK, Safety, and Tolerability of BG00012 in Chinese, Japanese, and Caucasian Healthy Volunteers (109HV108)

Healthy

Australia, China
University of Bern
Roche Pharma AG; University of Lausanne; University of Basel; Cantonal Hospital... and other collaborators

Completed

High Dose Ribavirin in the Treatment of Chronic Hepatitis C

Chronic Hepatitis C

Switzerland
Shenzhen Ausa Pharmed Co.,Ltd
Ruijin Hospital; Xuzhou Medical University; Second Affiliated Hospital of Nanchang...

Unknown

Efficacy of Amlodipine-Folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine

Essential Hypertension

China
GERCOR - Multidisciplinary Oncology Cooperative...
Bristol-Myers Squibb

Active, not recruiting

iRECIST Evaluation's Relevance for DCR in MMR/MSI Metastatic Colorectal Cancer Patients on Nivolumab and Ipilimumab (NIPICOL)

Metastatic Cancer Colorectal

France
CytomX Therapeutics

Terminated

PROCLAIM-CX-072: A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas

Lymphoma | Solid Tumor

United States, Netherlands, Poland, Spain, Ukraine, United Kingdom
Deepak C. D'Souza

Recruiting

Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans (DMT-Bolus)

Depression | Major Depression Disorder

United States
Medical University of Silesia

Completed

Adequacy of Anaesthesia for Colonoscopic Procedures (AoAColon)

Colonic Diseases, Functional

Poland
Haisco Pharmaceutical Group Co., Ltd.

Completed

Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease（NAFLD）

Hypercholesterolemia

China
King Abdul Aziz Specialist Hospital

Completed

Non Invasive and Invasive Ventilation Post Extubation

Respiratory Failure With Hypoxia

Saudi Arabia
Pfizer

Completed

Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

Staphylococcal Infections

United States
Hospital de Clinicas de Porto Alegre

Completed

Efficacy of Single Dose Anti-thymocyte Globulin in the Modulation of T Lymphocytes in Kidney Transplantation

Immunosuppression | Kidney Transplant; Complications

Brazil
Cancer Research UK
BioInvent International AB; Bloodwise

Completed

BI-1206 and an Anti-CD20 Antibody in Patients With CD32b Positive B-cell Lymphoma or Leukaemia

B-cell Lymphoma | Waldenström Macroglobulinemia | Chronic Lymphocytic Leukaemia

United Kingdom
Maastricht University Medical Center

Completed

Rhinitis, Cognition and Driving Performance

Seasonal Allergic Rhinitis | Cognition | Driving Ability

Netherlands
Organon and Co

Completed

An Open-Label Study of the Effects of Desloratadine (Aerius.) Treatment on the Quality of Life of Patients With Chronic Idiopathic Urticaria (Study P02540)

Urticaria
Organon and Co

Completed

Safety of Aerius Syrup in Pediatric Patients Aged 1-5 Years Old With Allergic Rhinitis or Chronic Idiopathic Urticaria (Study P04446AM1)(COMPLETED)

Rhinitis | Urticaria
Idorsia Pharmaceuticals Ltd.

Completed

Efficacy, Safety, and Tolerability Study of ACT-129968 in Patients With Seasonal Allergic Rhinitis (SAR)

Seasonal Allergic Rhinitis

United States
Utrecht Institute for Pharmaceutical Sciences
Royal Netherlands Navy

Completed

Effects of Levocetirizine and Hydroxyzine on Cognitive and Psychomotor Functioning During Simulated Diving

Healthy Volunteers

Netherlands
GlaxoSmithKline

Completed

Study Of Atopic Dermatitis In Pediatrics

Dermatitis, Atopic

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