Search clinical trials for: COMT

Total 328 results

Karolinska Institutet

Recruiting

COronary Microcirculation and Troponin Elevation in Septic Shock (COMTESS)

Sepsis | Myocardial Injury | Endothelial Dysfunction | Coronary Microvascular Dysfunction

Sweden
Centre Hospitalier Universitaire de Besancon
University of Franche-Comté

Recruiting

Impact of Perceptive, Executive and Emotional Factors on Decision-making of Pedestrian Face to Autonomous Vehicles. (VASIS)

Decision-making

France
Centre Oscar Lambret
Canceropôle Nord Ouest

Not yet recruiting

Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Second Line Treatment. (ePPS-2202)

Sarcoma Metastatic | Locally Advanced Soft Tissue Sarcoma

France
Hopital Nord Franche-Comte

Recruiting

Therapeutic Education Consultations With Diabetic Patients Treated With Intensified Insulin Therapy (DIABETE COACH)

Diabete Mellitus | Insulin Dependent Diabetes

France
Moon Surgical

Recruiting

Maestro 1.0 Post-Market Registry

Surgery

France
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Influence of Air Pollution on SPondyloarthritis Flare-ups and Resistance to Treatment (SPAIR)

Spondyloarthritis, Axial

France
Nova Scotia Health Authority
Dalhousie University

Recruiting

Pictou County PEP: A 6-Month, Home-Based, Personal Empowerment Program for Adults With a Chronic Medical Condition Living in Pictou County

Chronic Condition

Canada
Laboratoires Innothera
Floralis

Recruiting

Long-Term Post Thrombotic Syndrome Assessment (CELEST Long Term). (CELEST-LT)

Post Thrombotic Syndrome

France
University of Franche-Comté
University of Lorraine; University of Roehampton; LOBA association

Recruiting

Validation of a Dance as Therapy Program in Co-facilitation (VaDDanC)

Quality of Life | Stress | Depression, Anxiety | Body Image | Trauma, Psychological | Attachment Disorder | Social Relationship

France
Labrha
Statitec

Recruiting

Safety of Use and Efficacy of Pandora for Patients Suffering From Gonarthrosis (PANDORA2) (PANDORA2)

Knee Osteoarthritis

France, Monaco
Centre Hospitalier Universitaire de Besancon
Franche-Comté Electronique Mécanique Thermique et Optique - Sciences et Technologies...

Recruiting

NUclear MEdicine DIagnostic and Artificial Intelligence (NUMEDIA)

Hyperparathyroidism

France
Aptarion Biotech AG

Recruiting

Safety and Efficacy of AON-D21 in Severe Community-Acquired Pneumonia.

Community-acquired Pneumonia

Belgium, United Kingdom, Germany, France
MedsPLUS Consulting
National Institutes of Health (NIH); Lister Hill Center for Health Policy; Jenkins...

Not yet recruiting

Improving Recruitment and Retention for Diabetes Self-Management Education and Support

Diabetes Mellitus, Type 2 | Diabetes
Versantis AG

Recruiting

Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)™

Acute-On-Chronic Liver Failure | Ascites

Germany, Spain, Belgium, United States, France
Centre hospitalier de l'Université de Montréal...
St. Joseph's Healthcare Hamilton; McGill University; Canadian Institutes of Health... and other collaborators

Not yet recruiting

Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease (SSc-mILD)

Systemic Sclerosis | Interstitial Lung Disease | Systemic Sclerosis With Lung Involvement

Canada
Eagle Pharmaceuticals, Inc.

Recruiting

Blinded Efficacy and Safety Study of CAL02 IV Plus SOC in Subjects With Severe Community-Acquired Bacterial Pneumonia

Pneumonia, Bacterial

Spain, United States, France, Latvia, Romania, Chile, Argentina, Greece, South Africa, Georgia, Brazil, Czechia, Hungary, Colombia, Peru, Serbia
Evolucare Technologies
Assistance Publique - Hôpitaux de Paris; Slb Pharma; BPIfrance

Recruiting

OphtAI Diagnostic Performance Validation for Automated Screening of Eye Diseases (OPHTAI-EVAL)

Glaucoma | Age-Related Macular Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Age-related Maculopathy

France
Biotest

Recruiting

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP) (ESsCAPE)

Community-acquired Pneumonia

Australia, Spain, Israel, France, Brazil, United Kingdom, United States, Germany, Philippines, Belgium, Romania, Czechia, Hungary, Austria, Argentina, South Africa, New Zealand
University Hospital, Clermont-Ferrand
Research on Healthcare Performance Lab U1290

Recruiting

Access to Pediatric Rheumatology Centers for JIA Patients: Factors Associated With Time to Access Pediatric Rheumatology Centers (AJILITT)

Juvenile Idiopathic Arthritis

France
Centre Hospitalier Universitaire de Nice

Recruiting

Same Day Ambulatory Appendectomy (SAMBA) (SAMBA)

Appendicitis

France, Réunion
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Use of Upadacitinib Tablets in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis in Real World (UPDATE)

Atopic Dermatitis

France
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Treatment Patterns of Upadacitinib When Given Alone or Co-Administered With Methotrexate in Adult Participants With Active Psoriatic Arthritis (UPtimum-PsA)

Psoriatic Arthritis

France, Greece, Italy, Germany
Regeneron Pharmaceuticals

Recruiting

A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery

Melanoma

United States, Australia, Spain, United Kingdom, Canada, Brazil, Mexico, Germany, Ireland, South Africa, France, Israel, Georgia, Turkey, Italy, Poland, Chile, Argentina, Belgium, Czechia, Romania, Greece
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Impact of the Experience of Anaesthetists in Changing Ventilation Strategies During Panendoscopy on the Incidence of Intraoperative Hypoxaemia

ENT Tumor

France
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Comparison of HFNO and FMV on Desaturations During Panendoscopy Under General Anesthesia

ENT Tumor

France
AbbVie
Genmab

Recruiting

A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL) (EPCORE DLBCL-2)

Diffuse Large B-Cell Lymphoma

Korea, Republic of, Spain, Japan, Israel, Australia, Poland, Netherlands, Sweden, Greece, Taiwan, Italy, Belgium, Denmark, Switzerland, France, Bulgaria, Hungary, Austria, New Zealand, Czechia, Croatia, Brazil, China, United States, Canada and more
Centre Hospitalier Universitaire de Besancon

Recruiting

Interest of an Adapted Physical Activity (APA) Program Among Patients With Juvenile Idiopathic Arthritis: a Feasibility and Efficacy Preliminary Study (ATHLETIQUE)

Juvenile Idiopathic Arthritis

France
Centre Hospitalier Universitaire de Besancon
GERCOR - Multidisciplinary Oncology Cooperative Group; PRODIGE

Recruiting

Evaluation of the Interest to Combine a CD4 Th1-inducer Cancer Vaccine Derived From Telomerase and Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma (TERTIO)

Hepatocellular Carcinoma

France
University Hospital, Angers
Direction Générale de l'Offre de Soins; Agence régionale de santé, région Pays... and other collaborators

Recruiting

Evaluation of the Effectiveness of a Protocol for the Management of Female Functional Urinary Signs (PharmaCyst')

Cystitis Acute

France
UNICANCER
Servier

Recruiting

Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer (LOGICAN)

Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Esophagus Adenocarcinoma

France
Centre Hospitalier Universitaire de Besancon

Recruiting

Regorafenib With Low-dose Chemotherapies and Aspirin Followed by Standard Chemotherapies in Metastatic Colorectal Cancer (REPROGRAM-02)

Metastatic Colorectal Cancer

France
Le Syndicat Intercommunal pour le Thermalisme et...
University Grenoble Alps; Floralis

Recruiting

Assessment of the Effect of Spa Therapy on the Quality of Life of Patients With Chronic Venous Insufficiency (NEYRAC) (NEYRAC)

Chronic Venous Insufficiency

France
AbbVie
Genmab

Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma (EPCORE FL-1)

Follicular Lymphoma (FL)

Austria, Greece, Israel, Korea, Republic of, Spain, Hungary, Sweden, Switzerland, France, Poland, Taiwan, Australia, Denmark, New Zealand, Turkey, Italy, Netherlands, Belgium, Canada, South Africa, Czechia, Brazil, Germany, Argentina, United... and more
Centre Hospitalier Universitaire de Besancon
University of Franche-Comté

Recruiting

Attachment Style and Mentalization Impact Among Women Victims of Domestic Violence (FEMATAM)

Violence, Domestic

France
Paris Sudden Death Expertise Center
Centre Hospitalier René Dubos; Hospices Civils de Lyon; University Hospital,... and other collaborators

Recruiting

S-ICD French Cohort Study (HONEST) (HONEST)

Implantable Defibrillator User | Sudden Cardiac Death

France
Hopital Nord Franche-Comte

Recruiting

Smart Bra for Diagnosing Breast Cancer (CBRA)

Breast Cancer | Medical Device

France
University Hospital, Toulouse

Recruiting

New IMPLANTARY SURGERY Protocol ASSISTED BY PASSIVE ROBOTIQUE: Pilot Study (NAVIMPLANT)

Dental Implants

France
Britannia Pharmaceuticals Ltd.

Recruiting

Long-Term Observational Study on Effectiveness and Safety of Lecigon in Patients With Advanced Parkinson's Disease (ELEGANCE)

Advanced Parkinson Disease

Germany, Spain, Austria, Croatia, Romania, Slovenia, Belgium, Bulgaria, Czechia, Hungary, Ireland, Netherlands, Sweden
University Hospital, Clermont-Ferrand

Recruiting

Physical Restraints in Intensive Care Unit Patients (ARBORéa)

Critically Ill | Delirium Confusional State | Agitation,Psychomotor | Intensive Care Unit Delirium

France
Merck Sharp & Dohme LLC
Eisai Inc.

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014)

Metastatic Esophageal Squamous Cell Carcinoma

Argentina, Chile, United States, Canada, China, Costa Rica, Denmark, France, Guatemala, Hong Kong, Hungary, Italy, Japan, Korea, Republic of, Russian Federation, Spain, Taiwan, Turkey, United Kingdom, Romania, Ukraine, Singapore, Ma... and more
Centre Hospitalier Universitaire de Besancon
Novartis; National Cancer Institute, France

Recruiting

Combination of Spartalizumab, mDCF and Radiotherapy in Patients With Metastatic Squamous Cell Anal Carcinoma (SPARTANA)

Squamous Cell Anal Carcinoma | Metastatic Squamous Cell Carcinoma

France
Centre Hospitalier Universitaire de Besancon
University of Franche-Comté; University of Burgundy

Recruiting

Routine Electronic Monitoring Of Quality Of Life -Poumon (REMOQOL-Poumon)

Lung Cancer | Non Small Cell Lung Cancer

France
Inventiva Pharma

Recruiting

A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 ) (NATiV3)

NASH - Nonalcoholic Steatohepatitis

United States, Argentina, Australia, Austria, Belgium, France, Germany, Israel, Portugal, Spain, United Kingdom, Canada, Italy, China, Brazil, Netherlands, Hungary, Bulgaria, Chile, Czechia, Mexico, Poland, Puerto Rico, South Africa, Uk...
Hopital Nord Franche-Comte

Recruiting

Reduction of Anterior Glenohumeral Dislocation in Ventral Decubitus Versus Dorsal Decubitus Under Procedural Sedation (EPOLUX)

Emergencies | Anterior Shoulder Dislocation | Reduction

France
UGECAM Rhône-Alpes
Hospices Civils de Lyon; University of Lyon; University of Franche-Comté

Recruiting

Effects of FES-Rowing in Neurological Disorders (FES-ROW) (FES-ROW)

Spinal Cord Injuries

France
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Recruiting

Correlation Between COMT Val158Met Polymorphism and Dopaminergic Transporter Density (DAT) in Obese Women

Obesity

Brazil
Centre Hospitalier Universitaire de Besancon

Recruiting

Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening (PREDICT-IRFC)

Colorectal Cancer

France
Abbott Medical Devices

Recruiting

Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study (ARB-PMCF)

Mitral Regurgitation | Valvular Heart Disease | Tricuspid Regurgitation

Netherlands, Italy, United States, Estonia, France, Germany, Spain
UNICANCER
National Cancer Institute, France; GORTEC

Recruiting

Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers (PembroMetaRT)

Squamous Cell Carcinoma of Head and Neck

France
Hospices Civils de Lyon

Not yet recruiting

PETRA: PErtuzumab and Trastuzumab Biosimilars Real Life Association for the First Line Treatment of HER2-positive Metastatic Breast Cancer, an Observational Prospective Multicenter Study (PETRA)

HER-2 Positive Breast Cancer

France

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