Search clinical trials for: Complement activation

Total 4210 results

Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Ablation of Focal Activation in Atrial Fibrillation (RETRO-AF)

Atrial Fibrillation | Arrhythmias, Cardiac | Arrhythmia | Atrial Fibrillation, Persistent | Cardiac Arrhythmia

United Kingdom
Foundation For Rare Disease Research
Institute for Asthma & Allergy; Virant Diagnostics, Inc.; MedBio Reference Laboratories...

Not yet recruiting

Angioedema Biomarker Research Study

Angioedema | Urticaria | C1 Inhibitor Deficiency | Angioedemas, Hereditary | Mastocytosis | Indolent Systemic Mastocytosis | Systemic Mastocytoses | ACE Inhibitor-Induced Angioedema
University Hospital, Strasbourg, France

Recruiting

Study of the Link Between Complement Activation and IgA Nephropathy Severity (ICONE)

IgA Nephropathy Severity in Kidney Transplantation

France
University Hospital, Basel, Switzerland
Swiss National Science Foundation; Pharming Technologies B.V.

Recruiting

Recombinant Human C1 Esterase Inhibitor (Conestat Alfa) in the Prevention of Acute Ischemic Cerebral and Renal Events After Transcatheter Aortic Valve Implantation (PAIR-TAVI)

Acute Renal Injury | Acute Ischemic Stroke

Switzerland
University of California, Davis

Active, not recruiting

Effect of Insect-derived Protein Supplements on Protein Synthesis and mTORC1 Activation

Effect of Food Supplement

United States
University of Washington
Medical University of South Carolina; National Center for Complementary and... and other collaborators

Completed

Living in Full Even With Pain Study (LIFE)

Musculoskeletal Pain | Chronic Pain

United States
University of Washington
Medical University of South Carolina; National Center for Complementary and... and other collaborators

Completed

Back on Track to Healthy Living Study (BOT)

Chronic Pain

United States
Vanderbilt University Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Mobile Phone Support for Adults and Support Persons to Live Well With Diabetes (FAMS 2)

Type 2 Diabetes

United States
Portsmouth Hospitals NHS Trust
Akari Therapuetics

Completed

The CASCADE Study - Measures of Complement Activation and Inflammation in Patients With Covid-19

Coronavirus

United Kingdom
University Hospital Inselspital, Berne
University of Bern

Completed

Characterizing the Immune Response and Neuronal Damage in COVID-19

Covid-19 | SARS-CoV Infection

Switzerland
University Hospital, Ghent

Completed

Complement Activation During Hemodialysis in Atypical Hemolytic Uraemic Syndrome as Underlying Kidney Disease

Atypical Hemolytic Uraemic Syndrome

Belgium
University of Maryland, College Park
University of Maryland, Baltimore; National Center for Complementary and Integrative...

Completed

Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase (HEAL Together)

Substance Use | Substance Use Disorders | Opioid-use Disorder | Retention in Care | Methadone Treatment | Peer Delivered | Medication for Opioid Use Disorder (MOUD) | Behavioral Activation

United States
Medical University Innsbruck

Completed

Platelets and Complement Activation in Coronary Artery Bypass Graft Surgery (CABG) (PAC)

Inflammatory Response | Cardiopulmonary Bypass | Platelet Dysfunction

Austria
Francis Corazza

Completed

Evaluation of Interleukine 6 (and Other Cytokines and Inflammatory Markers) in COVID-19 Patients With a Systemic Inflammatory Response Syndrome

COVID-19

Belgium
Melbourne Health
Sanofi

Withdrawn

Complement Activation in the Lysosomal Storage Disorders (CATALYST)

Lysosomal Storage Diseases | Fabry Disease | Niemann-Pick Disease, Type C | Gaucher Disease

Australia
Cedars-Sinai Medical Center
Alexion Pharmaceuticals

Completed

The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation (DUET)

Cardiac Allograft Vasculopathy | Antibody-mediated Rejection | Left Ventricular Dysfunction | Hyperacute Rejection of Cardiac Transplant | Heart Graft Dysfunction

United States
Regina Elena Cancer Institute
Icahn School of Medicine at Mount Sinai; University of Roma La Sapienza

Unknown

Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis | Relapse

United States, Italy
University Hospital, Basel, Switzerland

Completed

Characteristics of Patients With Hypersensitivity Reactions to Intravenous Iron Infusions

Iron-deficiency | Hypersensitivity Reactions

Switzerland
Icahn School of Medicine at Mount Sinai
National Center for Complementary and Integrative Health (NCCIH)

Completed

The Role Of Omega-3 Fatty Acids In Adolescent Depression

Depressive Disorder, Major

United States
Shimaa Abdeleem

Unknown

Effect of Platelet Storage on Complement Activation

Platelet Storage
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Withdrawn

Targeting Complement Activation in Antineutrophil Cytoplasmic Autoantibodies (ANCA)-Vasculitis - Eculizumab

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

United States
Rigshospitalet, Denmark
Bispebjerg Hospital

Completed

Effect of Methylprednisolone on Complement Activation in Patients Undergoing Total Knee-arthroplasty

Osteoarthrosis

Denmark
H. Lee Moffitt Cancer Center and Research Institute
Bayer; Pediatric Cancer Foundation

Completed

Sorafenib and Topotecan in Refractory/Recurrent Pediatric Malignancies

Solid Tumor

United States
Assistance Publique - Hôpitaux de Paris
European Georges Pompidou Hospital; Clinical haematology and BMT unit,Necker... and other collaborators

Completed

Complement and Graft-versus-host Disease

Allografted With Myeloablative Conditioning

France
University of Pittsburgh

Withdrawn

Cell Bound Complement Activation Proteins as Markers of Liver Injury

Hepatitis C

United States
NHS Greater Glasgow and Clyde
University of Glasgow

Unknown

Inhibition of Complement Activation (Eculizumab) in Guillain-Barre Syndrome Study (ICA-GBS)

Gullian Barre Syndrome

United Kingdom
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic Syndrome (STEC-HUS) (STEC-HUS)

Shiga-like Toxin-producing Escherichia Coli

Germany
Liaoning University of Traditional Chinese Medicine
Ministry of Science and Technology of the People´s Republic of China

Completed

Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index

Coronary Heart Disease | Stable Angina Pectoris

China
Radboud University Medical Center

Completed

In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia (VECTOR)

Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
Wolfson Medical Center

Unknown

Combined Treatment With Fresh Frozen Plasma and Rituximab (Mabthera) in Patients With Advanced Refractory Chronic Lymphocytic Leukemia

Advanced Refractory Chronic Lymphocytic Leukemia

Israel
Avant Immunotherapeutics

Completed

Safety and Efficacy of TP10, a Complement Inhibitor, in Adult Women Undergoing Cardiopulmonary Bypass Surgery

Myocardial Ischemia | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Coronary Arteriosclerosis

United States
University Hospital, Angers

Completed

Complement Activation and Central Nervous System Injury After Coronary Artery Surgery

Coronary Artery Bypass Grafting
Saint-Joseph University

Recruiting

Minimal Instrumentation With Intracanal Heating and Activation of Sodium Hypochlorite for the Management of Teeth With Periapical Lesions

Heating and Activation of Sodium Hypochlorite

Lebanon
Amsterdam UMC, location VUmc
Foundation for the National Institutes of Health

Not yet recruiting

Assessment of PET Tracers to Evaluate T Cell Change and Activation in Relation to Immunotherapy Treatment Response in Non-Small Cell Lung Cancer (iRelate)

NSCLC

Netherlands
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Markers of Favorable Response to Complement Inhibitors Therapy (OPTIMISE)

Myasthenia Gravis, Generalized

Italy
University Ghent
VZW Educatieve Lichaamsbeweging

Recruiting

Changing Trunk Muscle Activation in Patients With Recurrent Low Back Pain in Remission (MAS)

Remission | Recurrent Low Back Pain

Belgium
Tao Lin

Not yet recruiting

Eculizumab for Prevention of Antibody-Mediated Rejection in ABO-Incompatible Living Donor Kidney Transplantation

Kidney Transplantation

China
Shahirose Sadrudin Premji
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

A Chinese Version of the Thinking Health Program for East Asian Pregnant Immigrant People in Canada

Perinatal Depression

Canada
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Not yet recruiting

Adjunctive Doxycycline for Central Nervous System Tuberculosis (DIRECT)

Tuberculosis, Meningeal | Tuberculosis, Central Nervous System | Tuberculosis; Meningitis (Etiology) | Tuberculosis; Meningoencephalitis (Etiology)

Singapore
Westat
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Not yet recruiting

Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Young Gay/Bisexual Minority Men (IMPACT) (IMPACT)

HIV

United States
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault

Alcohol Drinking | Alcohol Problem | Posttraumatic Stress Symptom
National Healthcare Group Polyclinics
National Healthcare Group, Singapore

Recruiting

The PACT (Patient Activation Through Conversations) Study (PACT)

Diabetes Mellitus, Type 2 | Diabetes Mellitus

Singapore
Pakistan Institute of Living and Learning
Fatima Jinnah Women University

Not yet recruiting

Universally Delivered Interventions for Young People (Mindset-PK)

Distress, Emotional

Pakistan
The Miriam Hospital

Recruiting

Healthy Heart Habits-2 (HHH-2)

Acute Coronary Syndrome

United States
Medical University of Lublin

Recruiting

Relationship Between Circulating Sclerostin and Bone Lesions in Patients With Mastocytosis

Mastocytosis | Bones

Poland
King's College Hospital NHS Trust

Recruiting

The Incidence and Outcomes of Metabolically Active Brown Adipose Tissue (aBAT) in Patients With Pheochromocytoma or Paraganglioma (PPGLs)

Pheochromocytoma | Paraganglioma

United Kingdom
University of Thessaly

Not yet recruiting

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair (CoFA-TAAA)

Platelet Activation | Thoraco-abdominal Aortic Aneurysm Repair | Coagulation Factors Alterations

Greece
University Hospital, Toulouse

Not yet recruiting

Study of Cellular Heterogeneity in Patients With Mastocytosis (MastCellHet)

Mastocytosis

France
The Royal's Institute of Mental Health Research

Recruiting

Behavioural Activation Therapy and Esketamine for Resistant Depression

Bipolar Disorder | Depressive Disorder, Major | Depressive Disorder, Treatment-Resistant

Canada
University Hospital, Ghent

Recruiting

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) (PADECMO)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin | Cefazolin

Belgium

Search clinical trials for: Complement activation

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