Search clinical trials for: DMARD

Total 198 results

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

Heart Failure | Mitral Regurgitation

China
Yonsei University

Not yet recruiting

A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study) (DOVE)

Uterine Cervical Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Vulvar Cancer | Clear Cell Carcinoma | Vagina Neoplasm
Children's Hospital of Fudan University

Recruiting

Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy

Cholangitis | Anti-Bacterial Agents | Biliary Atresia

China
Zagazig University

Recruiting

Dydrogesterone-Primed Ovarian Stimulation Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in ICSI

Fertility Issues | Ovary Cyst

Egypt
National and Kapodistrian University of Athens

Recruiting

Cortisol Circadian Rhythm in Patients With RA (CortRyRA)

Rheumatoid Arthritis

Greece
Qilu Hospital of Shandong University

Recruiting

The Clinical Efficacy of Immunomodulators in RA Patients

Arthritis, Rheumatoid

China
Diakonhjemmet Hospital
Oslo University Hospital; University Hospital of North Norway; Helse Nord-Trøndelag... and other collaborators

Recruiting

Rheumatic IMmune-Related Adverse Events in Patients Treated With Immune Check Point Inhibitors (RIMRA)

Immune-related Adverse Event

Norway
Fundación Eduardo Anitua

Not yet recruiting

Plasma Rich in Growth Factors (PRGF) for the Treatment of Lichen Sclerosus Atrophicus of the Vulva (PRGF)

Lichen Sclerosus of Vulva
Sohag University

Not yet recruiting

Outcomes of Biological Therapy on Rheumatoid Arthritis

Rheumatoid Arthritis

Egypt
Bristol-Myers Squibb

Recruiting

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

Psoriatic Arthritis

Italy, United States, Australia, Argentina, Brazil, Czechia, France, Hungary, Mexico, Russian Federation, China, Poland, Finland, Colombia, United Kingdom, Bulgaria, Taiwan, Chile, Romania, Spain, Ireland
Liga Panamericana de Asociaciones de Reumatologia...

Recruiting

PANLAR's Latin American Registry of Rheumatic Patients Treated With Jak Inhibitors (PREJAK)

Arthritis, Rheumatoid | Arthritis, Psoriatic | Spondyloarthritis

Argentina
Tuen Mun Hospital

Not yet recruiting

Shingrix in Patients With Rheumatic Diseases: a Double-blind Placebo-controlled RCT

Herpes Zoster

China
University of Alabama at Birmingham
Patient-Centered Outcomes Research Institute

Recruiting

RA-PRO PRAGMATIC TRIAL (RA-PROPR)

Rheumatoid Arthritis

United States, Canada
Turkish League Against Rheumatism

Recruiting

Observational Registry of Patients With Rheumatoid Arthritis /Spondyloarthritis Using Biological or Targeted Synthetic DMARDs (BioSTaR)

Rheumatoid Arthritis | Spondyloarthritis

Turkey
University of Leeds
Samsung Bioepis Co., Ltd.

Not yet recruiting

Targeted Treatment Early With Etanercept + Methotrexate vs.T2T Care for DMARD-naïve Early RA Patients Based on naïve T-cell Stratification (TEEMS)

Rheumatoid Arthritis

United Kingdom
University of Nebraska

Recruiting

Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response

Rheumatoid Arthritis

United States
National Institute of Medical Sciences and Nutrition...

Recruiting

INCMNSZ - Rheumatoid Arthritis Cohort (IRAC)

Rheumatoid Arthritis | Early Rheumatoid Arthritis

Mexico
Flinders University
medac GmbH; University of South Australia

Recruiting

Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis

Rheumatoid Arthritis | Endothelial Dysfunction | Cardiovascular Risk Factor | Stiffness, Aortic

Australia
Frederiksberg University Hospital

Recruiting

Pain Mechanisms and Ultrasonographic Disease Activity in Psoriatic Arthritis (PIPA)

Psoriasis | Psoriatic Arthritis | Healthy Controls

Denmark
Seoul National University Hospital

Recruiting

Korean College of Rheumatology Biologics and Targeted Therapy Registry (KOBIO)

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

Korea, Republic of
Diakonhjemmet Hospital
Vestre Viken Hospital Trust; University Hospital of North Norway; St. Olavs Hospital and other collaborators

Recruiting

The Norwegian Antirheumatic Drug Register (NOR-DMARD)

Inflammatory Joint Diseases

Norway
Amgen

Completed

Study to Evaluate the Real-World Effectiveness, Safety and Tolerability of Treatment With Apremilast in Psoriatic Arthritis Patients Followed in Canadian Routine Care (APPRAISE) (APPRAISE)

Arthritis, Psoriatic

Canada
University Hospital Bispebjerg and Frederiksberg

Active, not recruiting

Assessing Pain by the painDETECT Questionnaire (PDQ)

Rheumatoid Arthritis | Spondylarthropathies | Inflammatory Arthritis | Psoriatic Arthritis
Astellas Pharma China, Inc.

Completed

A Study to Assess Safety and Efficacy of ASP015K in Participants With Rheumatoid Arthritis (RA) Who Had an Inadequate Response or Intolerance to Methotrexate (MTX)

Rheumatoid Arthritis (RA)

China, Korea, Republic of, Taiwan
SetPoint Medical Corporation

Active, not recruiting

Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis (RESET-RA)

Rheumatoid Arthritis

United States
Noha Mansour

Completed

Montelukast Use in Rheumatoid Arthritis

Rheumatoid Arthritis

Egypt
Alexandria University

Completed

Trivalent Chromium Treatment for Rheumatoid Arthritis

Rheumatoid Arthritis

Egypt
NYU Langone Health
Bristol-Myers Squibb; Dartmouth-Hitchcock Medical Center

Active, not recruiting

Rheumatoid Arthritis Memory B Cells and Abatacept (RAMBA)

Rheumatoid Arthritis

United States
GlaxoSmithKline
Iqvia Pty Ltd

Terminated

Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs) (contRAst 2)

Arthritis, Rheumatoid

United States, Australia, Germany, Japan, Korea, Republic of, Poland, Bulgaria, Estonia, Hungary, Mexico, Russian Federation, Spain, Thailand, Colombia, China, Argentina, United Kingdom, France
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

China
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Active, not recruiting

Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment (ADDORA-switch)

Rheumatoid Arthritis

Netherlands
Qilu Hospital of Shandong University

Active, not recruiting

Immunosuppressant Combined With Pirfenidone in CTD-ILD

Connective Tissue Diseases | Interstitial Lung Disease | Pirfenidone

China
AbbVie

Active, not recruiting

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD) (SELECT - PsA 1)

Psoriatic Arthritis

United States, Argentina, Australia, Belarus, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Estonia, Germany, Greece, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic... and more
SynAct Pharma Aps
NBCD A/S

Completed

A Safety & Efficacy Study of Treatment With AP1189 in Rheumatoid Arthritis Patients naïve to DMARD Treatment (EXPAND)

Rheumatoid Arthritis

Moldova, Republic of
University of Nebraska

Completed

Triple III Comparison of Leflunomide Alone Versus Two DMARD Combinations in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Teijin America, Inc.
Parexel

Completed

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral Doses of TCK-276 in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Biologics & Biosimilars Collective Intelligence...
Merck Sharp & Dohme LLC; Pfizer; AbbVie; University of Pittsburgh; Boehringer Ingelheim and other collaborators

Completed

Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis | Inflammatory Bowel Disease | Ankylosing Spondylitis
GlaxoSmithKline
Iqvia Pty Ltd

Completed

Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors (contRAst 3)

Arthritis, Rheumatoid

United States, Germany, Canada, Czechia, Poland, South Africa, Korea, Republic of, Spain, Japan, Argentina, Belgium, Hungary, United Kingdom, Italy, Lithuania
Bristol-Myers Squibb

Completed

Pharmacokinetics, Efficacy and Safety of Abatacept Administered Subcutaneously (SC) in Children and Adolescents With Active Polyarticular Juvenile Idiopathic Arthritis (pJIA) and Inadequate Response (IR) to Biologic or Non Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs)

Active Polyarticular Juvenile Idiopathic Arthritis

United States, Spain, Belgium, Italy, Argentina, Brazil, France, Germany, Mexico, Peru, Russian Federation, South Africa
AbbVie

Completed

A Phase 3 Study to Compare Upadacitinib to Abatacept in Subjects With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease- Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response or Intolerance to Biologic DMARDs

Rheumatoid Arthritis (RA)

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Czechia, Germany, Greece, Hungary, Ireland, Israel, Italy, Korea, Republic of, Latvia, Mexico, Netherlands, New Zealand, Poland, Portugal, Puerto Rico, Romania, Russian... and more
AbbVie

Active, not recruiting

A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy (KEEPsAKE 1)

Psoriatic Arthritis

United States, Argentina, Australia, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, Croatia, Czechia, Denmark, Estonia, Finland, Germany, Greece, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Malaysia, Mexico and more
AbbVie

Completed

A Study to Compare Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) With an Inadequate Response or Intolerance to Biologic DMARDs (SELECT-BEYOND)

Rheumatoid Arthritis

United States, Australia, Austria, Belgium, Canada, Czechia, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Israel, Korea, Republic of, Latvia, New Zealand, Poland, Portugal, Puerto Rico, Russian Federation, Slovakia, ... and more
Kasr El Aini Hospital

Active, not recruiting

Biologic Therapy in Pediatric JIA Uveitis

Juvenile Idiopathic Arthritis Associated Uveitis

Egypt
Karolinska Institutet

Active, not recruiting

Active Conventional Therapy Compared to Three Different Biologic Treatments in Early Rheumatoid Arthritis With Subsequent Dose Reduction

Rheumatoid Arthritis

Sweden, Denmark, Finland, Norway, Iceland, Netherlands
Gilead Sciences
Galapagos NV

Terminated

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Psoriatic Arthritis Who Are Naive to Biologic DMARD Therapy (PENGUIN 1)

Psoriatic Arthritis

Korea, Republic of, United States, Taiwan, Australia, Canada, Japan, Poland, Spain, New Zealand, Czechia, Hungary, Bulgaria, Russian Federation
Shanghai Henlius Biotech

Completed

A Randomised, Double-blind, Phase I/II Study to Evaluate the PK, PD, Safety, and Efficacy Between HLX01 and Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis and Inadequate Response to Treatment With DMARDs

Rheumatoid Arthritis
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

A Multicenter Study to Compare the Efficacy and Safety of the Combination of Etanercept and Methotrexate in Treatment of Rheumatoid Arthritis (DOTAR)

Rheumatoid Arthritis
Diakonhjemmet Hospital
The Research Council of Norway; South-Eastern Norway Regional Health Authority

Completed

Assessing Withdrawal of Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis (ARCTIC REWIND)

Rheumatoid Arthritis

Norway
Pfizer

Completed

Study of CE-224,535 A Twice Daily Pill To Control Rheumatoid Arthritis In Patients Who Have Not Totally Improved With Methotrexate

Arthritis, Rheumatoid

United States, Spain, Czechia, Korea, Republic of, Poland, Chile, Mexico
Gilead Sciences
Galapagos NV

Terminated

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Psoriatic Arthritis Who Have an Inadequate Response or Are Intolerant to Biologic DMARD Therapy (PENGUIN 2)

Psoriatic Arthritis

Korea, Republic of, United States, Australia, Belgium, Canada, Czechia, Hungary, Japan, Poland, Spain, Taiwan

Search clinical trials for: DMARD

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