Search clinical trials for: Intrathecal Injection

Total 11642 results

Guangzhou Medical University

Not yet recruiting

Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors

Leptomeningeal Metastasis

China
Rejukon Biopharm Inc.

Not yet recruiting

An IIT Clinical Study to Evaluate the Safety and Efficacy of a Single Intrathecal Injection of RJK002 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis
Muhammad Ilyas

Not yet recruiting

Impact of Intrathecal vs Intravenous Dexmedetomidine

Nausea and Vomiting, Postoperative
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Prospective Study of Whole-Brain RT Combined With Thiotepa Sheath Injection Combined With Systemic Therapy for the Primary Disease in the Treatment of Meningeal Metastases in Solid Tumors

Solid Tumor Leptomeningeal Metastasis

China
The Affiliated Hospital Of Guizhou Medical University

Recruiting

Treatment of Vasospasm of Aneurysmal Subarachnoid Hemorrhage With Intrathecal Nicardipine - FAST-IT Trial

Aneurysmal Subarachnoid Hemorrhage | Vasospasm

China
Second Affiliated Hospital of Nanchang University
Changhai Hospital

Recruiting

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage

China
Beijing Tiantan Hospital

Not yet recruiting

Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis (SPECIALS)

Amyotrophic Lateral Sclerosis

China
Chulalongkorn University

Not yet recruiting

Effectiveness of Intrathecal Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in Patients Undergoing Transurethral Resection of the Prostate

Transurethral Resection of Prostate

Thailand
West China Hospital

Not yet recruiting

Immune Checkpoint Inhibitors Intrathecal Injection in Patients With Leptomeningeal Metastases in NSCLC

NSCLC Associated With Leptomeningeal Metastases
Sohag University

Recruiting

The Pectoralis (PECS2) Block Versus Intrathecal Morphine

Post-operative Pain

Egypt
Ain Shams University

Recruiting

Single Shot Intrathecal Analgesia in Vaginal Delivery

Effectiveness of Single Shot Intra-thecal Analgesia in Multiparous Women Scheduled for Normal Vaginal Delivery

Egypt
UNICANCER
Seagen Inc.

Recruiting

Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease (ETIC-LM)

HER2-positive Metastatic Breast Cancer | Leptomeningeal Disease | Leptomeningeal Metastasis

France
Pacira Pharmaceuticals, Inc

Recruiting

Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers

Healthy

United States
Vestre Viken Hospital Trust
Oslo University Hospital; University Hospital of North Norway; Helse Stavanger... and other collaborators

Recruiting

Efficacy and Safety of Anti-PD-1/PD-L1 Treatment +/- UV1 Vaccination in Patients With Non-small Cell Lung Cancer (LUNGVAC)

Oncology | NSCLC Stage IV | NSCLC, Stage III

Norway
Mansoura University

Not yet recruiting

Opioid Free Anesthesia in Prolonged Surgery

Cancer, Bladder

Egypt
Fudan University

Recruiting

R-CDOP Combined With Intrathecal Methotrexate for DLBCL Patients With High-risk of CNS Relapse

Diffuse Large B-cell Lymphoma

China
Indiana University

Recruiting

ESP Block VS Intrathecal Opioid After Laparoscopic Colorectal Surgery

Surgery

United States
Sonoran Spine Research and Education Foundation

Recruiting

Does Intrathecal Morphine Affect Outcomes in Spine Deformity Surgery

Low Back Pain

United States
Kringle Pharma, Inc.

Recruiting

Phase 3 Study of KP-100IT in Subjects With Acute Spinal Cord Injury

Acute Spinal Cord Injury

Japan
Institut Cancerologie de l'Ouest
Esteve

Recruiting

OP2C : Prialt® Observatory in Clinical Practice (OP2C)

Refractory Pain

France
PT. Prodia Stem Cell Indonesia

Recruiting

Stem Cell and Conditioned Medium for Cerebral Palsy

Cerebral Palsy

Indonesia
University of Manitoba

Recruiting

Spinal Anesthesia For Enhanced Recovery After Liver Surgery (SAFER-L)

Pain, Postoperative | Liver Neoplasms | Hepatectomy

Canada
University of Chicago
Incyte Corporation

Recruiting

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | ALL, Childhood | ALL

United States
Sclnow Biotechnology Co., Ltd.

Not yet recruiting

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia

Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 6
Cairo University

Completed

Analgesic Efficacy of Sequential Rapid Versus Slow Intrathecal Injection Of Dexmedetomidine Followed by of Hyperbaric Bupivacaine in Inguinal Hernia Repair Surgery

Postoperative Pain

Egypt
University of Miami

Suspended

Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.

Post-operative Pain

United States
Amgen
Innovative Therapies For Children with Cancer Consortium; Therapeutic Advances...

Active, not recruiting

Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia (ALL)

Spain, United Kingdom, United States, Korea, Republic of, Czechia, France, Russian Federation, Saudi Arabia, Thailand, Canada, Italy, Singapore, Turkey, Taiwan, Portugal, Poland, Romania, Brazil, Australia, Greece, Argentina, Mexico, Austr... and more
Tisch Multiple Sclerosis Research Center of New...

Completed

Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis

Multiple Sclerosis

United States
Zagazig University

Active, not recruiting

Intrathecal Injection of Pethidine Plus Dexamethasone Versus Bupivacaine Alone

Postoperative Pain

Egypt
Centre Hospitalier Universitaire de Nice

Active, not recruiting

Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA® (SMAII)

Spinal Muscular Atrophy

France
Xinhua Hospital, Shanghai Jiao Tong University...

Completed

Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery (IMPAS)

Analgesia | Acute Pain | Post Operative Pain | Anorectal Disorder

China
Helwan University

Completed

Intrathecal Injection of Hyperbaric Bupivacaine Versus a Mixture of Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Lower Abdominal Surgery

Spinal Anesthesia | Lower Abdominal Surgery | Hyperbaric Bupivacaine | Isobaric Bupivacaine

Egypt
Ain Shams University

Completed

Intrathecal Dexmedetomidine to Decrease Postoperative Nausea and Vomiting and Shivering.

Intrathecal Dexmedetomidine

Egypt
Tisch Multiple Sclerosis Research Center of New...

No longer available

Expanded Access to Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis

Multiple Sclerosis

United States
University of Liege

Completed

Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery

Analgesia

Belgium
Sohag University

Completed

Comparative Study Between the Efficacy of The Serratus Anterior Plane Block and Lumbar Intrathecal Fentanyl Injection for Postoperative Analgesia After Modified Radical Mastectomy

Patients Undergoing Modified Radical Mastectomy

Egypt
Institut Cancerologie de l'Ouest

Completed

Place of Intrathecal Analgesia to Improve the Quality of Life of Painful Cancer Patients (QUALITHEC01)

Cancer | Injections, Spinal

France
The Foundation for Orthopaedics and Regenerative...

Suspended

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intrathecal Injection for ALS

Amyotrophic Lateral Sclerosis

Antigua and Barbuda
Fayoum University Hospital

Completed

Erectae Spinae Block Versus Intrathecal Morphine for Postoperative Analgesis in Lumbar Surgeries

Analgesia | Post-operative

Egypt
South China Children's Leukemia Group

Completed

A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia

Childhood Acute Promyelocytic Leukemia

China
Hôpital de la Croix-Rousse
Hospices Civils de Lyon

Completed

Intrathecal Chloroprocaine for Lower Limb Arthroplasty

Lower Limb Arthroplasty Under Chloroprocaine Spinal Anesthesia

France
Corestem, Inc.

Completed

Safety and Efficacy Study of Autologous Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis | ALS

Korea, Republic of
Vanderbilt University
Medtronic

Completed

Intrathecal (IT) Baclofen Drug Distribution (ITB)

Muscle Spasticity

United States
Yonsei University

Completed

Analgesic Effect of Intrathecal Morphine Combined With Low Dose Local Anesthetics on Postoperative Analgesia After Liver Resection

Patients Receiving Hepatectomy Under General Anesthesia

Korea, Republic of
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Intrathecal Morphine for Radical Robot Assisted Prostatectomy (TORNADO) (TORNADO)

Catheter Related Complication

Italy
Sintetica SA
Cross S.A.

Completed

Dose-finding Study of Intrathecal Paracetamol Administered Immediately Before Spinal Anaesthesia

Phase 1: Pain Management | Phase 2: Pain Management

Switzerland
The Foundation for Orthopaedics and Regenerative...

Suspended

Safety of Cultured Autologous Adult Adipose Derived Mesenchymal Stem Cell Intrathecal Injection for SCI

Spinal Cord Injuries

Greece
Myovant Sciences GmbH

Completed

Study of Relugolix Alone and Relugolix Combined With Hormonal Add-Back Therapy in Healthy Premenopausal Female Participants

Healthy

United States
Sintetica SA
Cross Research S.A.

Completed

Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures

Pain, Postoperative

Switzerland
Pacira Pharmaceuticals, Inc

Terminated

Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Administered Via a Single Intrathecal Injection to Healthy Volunteers

Healthy

United States

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