Search clinical trials for: Lomustine

Total 97 results

Philogen S.p.A.

Not yet recruiting

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence (GLIOSTELLA)

Glioblastoma
National Cancer Institute (NCI)

Not yet recruiting

Anti-Lag-3 (Relatlinib) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent Glioblastoma
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) (RECSUR)

Glioblastoma | Glioblastoma Multiforme | Recurrent Glioblastoma | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain | Astrocytoma of Brain | Astrocytoma, Malignant

United States, Germany, Netherlands, Switzerland, Belgium
Darell Bigner
Istari Oncology, Inc.

Not yet recruiting

Lerapolturev (PVSRIPO) in GBM

Recurrent Supratentorial Glioblastoma

United States
European Organisation for Research and Treatment...

Recruiting

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study (LEGATO)

First Progression of Glioblastoma

Netherlands, Austria, Germany
CarThera

Recruiting

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM (SONOBIRD)

Glioblastoma | GBM | Recurrent Glioblastoma

France, United States, Spain, Belgium, Germany, Italy, Netherlands
University Hospital Heidelberg
Ruhr University of Bochum; Universitätsmedizin Mannheim

Recruiting

A Clinical Study to Improve Brain Function and Quality of Life of Patients With Newly Diagnosed Brain Tumors (Gliomas). (ImproveCodel)

Oligodendroglioma

Germany
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Glioblastoma | Gliosarcoma

United States
The University of Texas Health Science Center at...

Recruiting

Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma

Glioblastoma

United States
Philogen S.p.A.

Recruiting

A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression (GLIOSTAR)

Glioblastoma

France, Germany, Italy, Switzerland
European Organisation for Research and Treatment...

Recruiting

Personalized Risk-Adapted Therapy in Post-Pubertal Patients With Newly-Diagnosed Medulloblastoma (PersoMed-I)

Medulloblastoma

France, Netherlands, Spain, Australia, Germany, Switzerland, Austria, Italy
Theodore S. Johnson
National Cancer Institute (NCI); Emory University; Augusta University

Recruiting

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Glioblastoma | Ependymoma | Medulloblastoma | Diffuse Intrinsic Pontine Glioma

United States
Global Coalition for Adaptive Research
Bayer; Kazia Therapeutics Limited; Biohaven Pharmaceuticals, Inc.; Kintara Therapeutics... and other collaborators

Recruiting

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (GBM AGILE)

Glioblastoma

United States, France, Germany, Canada, Australia, Switzerland
VBI Vaccines Inc.

Recruiting

Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects

Glioblastoma Multiforme

United States
Amsterdam UMC, location VUmc

Recruiting

A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme (STELLAR)

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, Adult | Recurrent Brain Tumor

Netherlands
Children's Oncology Group
National Cancer Institute (NCI)

Suspended

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Medulloblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Medulloblastoma

United States, Canada, Saudi Arabia, Puerto Rico, Australia
Philogen S.p.A.

Withdrawn

Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression (GLIOASTRA)

Glioblastoma
Actuate Therapeutics Inc.

Active, not recruiting

9-ING-41 in Patients With Advanced Cancers

Sarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditions

United States, Belgium, Canada, Spain, France, Netherlands, Portugal
Biodexa Pharmaceuticals

Active, not recruiting

A Study of Intra-tumoral Administered MTX110 in Patients With Recurrent Glioblastoma (MAGIC-G1)

Recurrent Glioblastoma

United States
Eli Lilly and Company

Active, not recruiting

A Study in Recurrent Glioblastoma (GB)

Glioblastoma

United States, Germany, Spain, Belgium, Italy, Australia, Canada, France, Poland
DelMar Pharmaceuticals, Inc.

Terminated

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM (STAR-3)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM

United States
Saint John's Cancer Institute

Completed

A Longitudinal Assessment of Tumor Evolution in Patients With Brain Cancer

Newly Diagnosed High Grade Glioma

United States
Aadi Bioscience, Inc.

Completed

Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma

High Grade Recurrent Glioma and Newly Diagnosed Glioblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

Untreated Childhood Medulloblastoma

United States, Canada, Australia, New Zealand, Switzerland, Netherlands
CNS Pharmaceuticals, Inc.
Worldwide Clinical Trials

Active, not recruiting

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme, Adult

United States, Spain, France, Switzerland, Italy
Karyopharm Therapeutics Inc

Terminated

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Glioblastoma Multiforme

United States, Canada
Eli Lilly and Company

Active, not recruiting

A Dose-Escalation Study in Participants With Recurrent Malignant Glioma

Glioma

United States, Spain
Refnot-Pharm Ltd

Completed

Effect of Refnot on Immunity in Cancer Patients (R-2)

Solid Tumor
European Organisation for Research and Treatment...
Amgen

Withdrawn

Phase II Trial of Romiplostim for Thrombocytopenia Induced by Lomustine at First Progression of MGMT Promoter-meth Glioblastoma (RIGOLETTO)

First Progression of MGMT Promoter-methylated Glioblastoma

Spain, Switzerland
Varun Monga, MD
University of Iowa

Withdrawn

Golden Halo, Static Magnetic and Electric Field Device, in Recurrent Glioblastoma

Glioblastoma | Recurrent Glioblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Central Nervous System Neoplasm | Spinal Cord Neoplasm

United States
Emory University
National Cancer Institute (NCI)

Withdrawn

Inducing a Hypothyroxinemic State in Patients With Recurrent Glioblastoma or Gliosarcoma

Recurrent Glioblastoma | Recurrent Gliosarcoma
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC

Completed

Intravenous Chemotherapy or Oral Chemotherapy in Treating Patients With Previously Untreated Stage III-IV HIV-Associated Non-Hodgkin Lymphoma

AIDS-related Peripheral/Systemic Lymphoma | AIDS-related Diffuse Large Cell Lymphoma | AIDS-related Diffuse Mixed Cell Lymphoma | AIDS-related Diffuse Small Cleaved Cell Lymphoma | AIDS-related Immunoblastic Large Cell Lymphoma | AIDS-related Lymphoblastic Lymphoma | AIDS-related Small Noncleaved... and other conditions

Zimbabwe, Kenya
Istituto Oncologico Veneto IRCCS
BAYER S.p.A. - Italia

Completed

Regorafenib in Relapsed Glioblastoma (REGOMA)

Glioblastoma Multiforme

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

Recurrent Glioblastoma | IDH Family Wildtype | Recurrent Anaplastic Astrocytoma

United States
Universitätsklinikum Hamburg-Eppendorf
Deutsche Kinderkrebsstiftung

Active, not recruiting

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Brain Tumors

Germany, Denmark, United Kingdom, Belgium, Poland, Ireland, Austria, Italy, Czechia, France, Netherlands, Norway, Portugal, Spain, Sweden, Switzerland
Massachusetts General Hospital

Completed

Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI

Glioblastoma

United States
Orbus Therapeutics, Inc.

Active, not recruiting

Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients (STELLAR)

Anaplastic Astrocytoma | Recurrent Anaplastic Astrocytoma

United States, United Kingdom, France, Canada, Italy, Germany, Netherlands, Belgium
Sidney Kimmel Comprehensive Cancer Center at Johns...
Matthew Larson Foundation

Terminated

Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma

Medulloblastoma

United States
Proximagen, LLC

Terminated

Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)

Solid Tumors (Phase 1) | Relapsed/Recurrent GBM (Phase 2)

United States, Spain
Sahlgrenska University Hospital, Sweden
Karolinska University Hospital; St. Olavs Hospital; University Hospital, Linkoeping and other collaborators

Completed

Disulfiram in Recurrent Glioblastoma

Glioma | Glioblastoma

Sweden, Norway
European Organisation for Research and Treatment...
Hoffmann-La Roche

Completed

Bevacizumab and Lomustine for Recurrent GBM

Cognition Disorders | Glioblastoma Multiforme | Disability Evaluation

Netherlands
Novartis Pharmaceuticals

Completed

Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma Multiforme

United States, Belgium, Australia, Spain, France, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; Eastern Cooperative Oncology Group and other collaborators

Completed

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors
Fundación Pública Andaluza para la gestión de la...
Spanish Network for Research in Infectious Diseases

Completed

Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae (SIMPLIFY)

Enterobacteriaceae Infections

Spain
AbbVie
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas (INTELLANCE-2)

Glioblastoma

United States, Australia, Austria, Belgium, Canada, Czechia, Finland, France, Germany, Hungary, Ireland, Italy, Korea, Republic of, Mexico, Netherlands, Poland, Singapore, Spain, Switzerland, Taiwan, United Kingdom
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma

Brain and Central Nervous System Tumors

United States
M.D. Anderson Cancer Center

Completed

Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)

Glioblastoma | Brain Cancer

United States
Tocagen Inc.

Terminated

The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma (Toca5)

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States, Korea, Republic of, Canada, Israel

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