Search clinical trials for: Multicenter randomized trial

Total 46106 results

KidSIM Simulation Program
University of Alabama at Birmingham; Columbia University; University of Southern... and other collaborators

Not yet recruiting

Evaluation of the InterFACE-AR System for Cardiopulmonary Arrest: A Multicenter, Randomized Controlled Trial (InterFACE-AR)

Cardiac Arrest | Cardiopulmonary Arrest
Peking University First Hospital

Recruiting

Comparison of MRI Artificial Intelligence-guided cTB Versus Routine cTB in Prostate Cancer Diagnosis

Prostate Cancer

China
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Immediate Corticosteroid Therapy and Rituximab to Prevent Generalization in Ocular Myasthenia: a PROBE Multicenter Open-label Randomized Controlled Trial. (IMCOMG)

Ocular Myasthenia Gravis
Major Extremity Trauma Research Consortium

Not yet recruiting

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures: A Multicenter Randomized Controlled Trial (iVAC)

Wound Heal | Wound Complication | Wound Dehiscence | Fracture of Tibia | Infected Wound
Peking University First Hospital

Recruiting

Fuzheng Nizeng Formula for Chronic Atrophic Gastritis With Low-grade Intraepithelial Neoplasia, a Multicenter Randomized Controlled Trial

Atrophic Gastritis With Low-grade Intraepithelial Neoplasia

China
Beijing Tiantan Hospital

Not yet recruiting

Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke (TAPIS)

Ischemic Stroke, Acute
The Fourth Affiliated Hospital of China Medical...

Recruiting

A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy Followed by Ticagrelor Versus 6-month Dual Antiplatelet Therapy Followed by Ticagrelor After Implanting Bridge

Brain Disease | Vertebral Artery Stenosis

China
Huashan Hospital

Recruiting

aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial (ASTIM-MT)

Intracranial Pressure Increase | Aneurysmal Subarachnoid Hemorrhage

China
Peking University Third Hospital
Beijing Yanqing Hospital

Recruiting

A Prospective Multicenter Cohort Study About Internal Fixation Using PFUN Versus PFNA for Femoral Intertrochanteric Fracture

Femoral Intertrochanteric Fractures

China
Auckland City Hospital

Not yet recruiting

Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery (Balanced-2)

Delirium | Anesthesia | Cognitive Decline | Cognition Disorder | Surgery-Complications | Delirium, Postoperative
University Hospital, Tours
Hospices Civils de Lyon; Centre Hospitalier Universitaire Dijon; CHU de Reims; University... and other collaborators

Not yet recruiting

Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial (CARVECIR)

Clinically Significant Portal Hypertension | Asymptomatic Cirrhosis

France
The Third People's Hospital of Hangzhou
The Third Affiliated hospital of Zhejiang Chinese Medical University

Recruiting

Efficacy of Electroacupuncture Combined With Pregabalin in the Treatment of Trigeminal Herpetic Neuralgia: a Multicenter Randomized Controlled Trial Study Protocol

Trigeminal Herpetic Neuralgia

China
Cardresearch

Recruiting

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial (REVIVE)

Chronic Fatigue Syndrome | Long COVID-19 Syndrome

Brazil
PT Bio Farma

Recruiting

Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial

Safety Issues | Effect of Drug

Indonesia
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Trial of ZX-7101A Tablets to Evaluate the Efficacy and Safety in the Treatment of Uncomplicated Influenza in Adolescents (ZX-7101A-207)

Respiratory Viral Infection

China
Mao Jianhua
Tongji Hospital; Xinhua Hospital, Shanghai Jiao Tong University School of Medicine and other collaborators

Recruiting

Study of Adrenocorticotropic Hormone on Children With Frequent Relapse or Steroid-dependent Nephrotic Syndrome: a Prospective, Multicenter, Randomized，Open-label Clinical Trial.

Nephrotic Syndrome in Children

China
Escient Pharmaceuticals, Inc

Recruiting

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria (CALM-CSU)

Chronic Spontaneous Urticaria

Spain, United States, Germany, Canada, Poland, Netherlands
University of California, San Diego
National Institute on Drug Abuse (NIDA); RTI International; Drexel University

Recruiting

A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs (SAIA-SSP-HIV)

HIV Infections

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia: a Multicenter Open-label Randomized Controlled Trial (DASSOH)

Hyponatremia
University of Campinas, Brazil

Recruiting

Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions A Multicenter Randomized Clinical Trial.

Gingival Recession

Brazil
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Impact of Annual Versus Biannual Infusions of Ocrelizumab in Patients With Active MS,After 2 Years of Initial Treatment, on Freedom From Radiological Disease Activity at Two Years: a Multicenter Randomized Controlled Non-inferiority Trial (WINDOCRE)

Multiple Sclerosis

France
University Hospital, Tours

Not yet recruiting

Health-Economic Evaluation of Early Diagnosis of Epithalial Ovarian Cancer Recurrence Using the ROMA Score: a Prospective Multicenter Randomized Trial (ROMECO)

Epithelial Ovarian Cancer
Rush University Medical Center
International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports...

Recruiting

Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

Meniscus Tear, Tibial

United States
Göteborg University
Forte; Medtanken Group AB; FoU i Västra Götalandsregionen

Recruiting

The Effect and Experience of the Parental Program AFFEKT

Quality of Life | Stress | Parent-Child Relations | Parenting | Behavior, Child

Sweden
Shandong University

Recruiting

High-dose Dexamethasone Plus Hetrombopag vs High-dose Dexamethasone Alone as Frontline Treatment for Newly Diagnosed Adult Primary Immune Thrombocytopenia: A Prospective, Multicenter, Randomized Trial

ITP - Immune Thrombocytopenia

China
National Cancer Institute, Lithuania

Recruiting

Transanal Irrigation - Best Treatment Possibility for Low Anterior Resection Syndrome? Multicenter, Randomized Clinical Trial

Low Anterior Resection Syndrome

Lithuania
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

the Impact of Occupational Therapy : a Multicenter Randomized Controlled Trial (OCEAN-OT)

Quality of Life | Cancer | Elderly Patient
Tianjin Medical University Cancer Institute and...

Recruiting

A Multicenter, Randomized, Open, Phase III Trial of ddEC-THPvs Evaluating the Efficacy and Safety of TCHP Neoadjuvant Therapy for HER2-positive Breast Cancer

HER-2 Positive Breast Cancer

China
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

A Multicenter, Randomized, Double-blind Phase II Trial to Evaluate GM1 Prevention of Peripheral Neuropathy in Patients With Breast Cancer

To Evaluate the Effectiveness of GM1 in the Prevention of Albumin-paclitaxel Therapy Induced Peripheral Neuropathy in Breast Cancer Patients
Shanghai Huihe Medical Technology Co., Ltd

Not yet recruiting

A Prospective, Multicenter, Randomized Controlled Trial to Evaluate the Efficacy and Safety of the Transcatheter Tricuspid Valvuloplasty System in Patients With Severe or Above Tricuspid Regurgitation

Tricuspid Regurgitation
The First Affiliated Hospital of University of...

Not yet recruiting

A Multicenter Prospective Randomized Controlled Study of RPD Versus LPD

Pancreatic Cancer | Common Bile Duct Diseases | Periampullary Carcinoma
xiao-yan xie

Not yet recruiting

Contrast-Enhanced Ultrasound vs Conventional US-guided Percutaneous Needle Biopsy for Pancreatic Diseases: Prospective Multicenter Randomized Controlled Trial

Pancreatic Disease

China
Royal Victoria Hospital, Canada

Not yet recruiting

Comparing the Effect of Adding a Remote Self-reporting Tool for Distress and Fit-for-purpose Mental Health & Addictions Service to Usual Case Management on Dropout Rates in a Vocational Training Program (TeachMeToBuild)

Substance Use Disorders | Distress, Emotional | Mental Health Issue

Canada
Yonsei University

Recruiting

PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial

Atrioventricular Block | Left Bundle Branch Area Pacing | Bradyarrhythmia

Korea, Republic of
Beijing Tiantan Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy of Pentoxifylline on Cerebrovascular Function in Patients With Cerebral Small Vessel Disease(PERFORM) (PERFORM)

Cerebral Small Vessel Diseases

China
Taiyuan Li

Not yet recruiting

Robotic Transanal Specimen Extraction Surgery Versus Robotic Transabdominal Incision Specimen Extraction Surgery for Patients With Rectal Cancer: A Multicenter Randomized Controlled Trial

Rectal Neoplasms | Robotic Surgery | Natural Orifice Specimen Extraction Surgery

China
University Medical Center Groningen

Not yet recruiting

Clinical Validation of the C-Arm Rotational View (CARV) to Avoid Rotational Malalignment After Intramedullary Nailing of Tibial Shaft Fractures.

Surgery | Tibial Fractures | Complication,Postoperative

Australia, Netherlands
First Affiliated Hospital of Zhejiang University
Zhejiang Cancer Hospital; West China Hospital; Third Affiliated Hospital, Sun... and other collaborators

Recruiting

A Multicenter, Randomized, Parallel-controlled Clinical Trial Protocol to Validate the Safety and Efficacy of a Steep Pulse Therapy System for the Treatment of Liver Tumors

A Steep Pulse Therapy System for the Treatment of Liver Tumors

China
Rijnstate Hospital
Medtronic; Abbott

Recruiting

Effects of Active Versus Passive Recharge Burst Spinal Cord Stimulation on Pain Experience in Persistent Spinal Pain Syndrome Type 2: A Multicenter Randomized Trial (BURST-RAP Study) (BURST-RAP)

Failed Back Surgery Syndrome | Persistent Spinal Pain Syndrome Type 2

Netherlands
wang shusen

Recruiting

Tucidinostat and Metronomic Capecitabine for Metastatic Triple-negative Breast Cancer:a Multicenter,Open-label, Randomized Controlled, Phase II Clinical Trial

Triple Negative Breast Cancer

China
CHU de Reims

Recruiting

Virtual Reality Hypnosis Versus Inhaled Nitrous Oxide in Anterior Shoulder Dislocation Reduction: an Open Multicenter Randomized Controlled Trial

Shoulder Dislocation

France
Assistance Publique Hopitaux De Marseille

Recruiting

Evaluation of the Efficacy of Early Implantation of a Percutaneous Left Ventricular Assist Devices in Acute Coronary Syndrome Complicated by Cardiogenic Shock Compared to Conventional Therapy: a Prospective, Multicenter, Randomized, Controlled and Open-label Clinical Trial (ULYSS)

Cardiogenic Shock

France
Wex Pharmaceuticals Inc.

Recruiting

A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

Chemotherapy-induced Peripheral Neuropathy | Chemotherapy-induced Neuropathic Pain

United States
Chengdu Easton Biopharmaceuticals Co,Ltd

Recruiting

A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Clinical Efficacy and Safety of Yogliptin Tablets

Type 2 Diabetes

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
Nanjing First Hospital, Nanjing Medical University; Wuxi People's Hospital; Changzhou... and other collaborators

Recruiting

Effects of Liraglutide, Empagliflozin and Linagliptin on the Cognitive Function in T2DM Patients With Mild Cognitive Impairment: a Multicenter, Randomized, Parallel Controlled Clinical Trial (LIGHT-MCI)

Type 2 Diabetes Mellitus | Mild Cognitive Impairment

China
Beijing Tiantan Hospital
GrandPharma (China) Co., Ltd.

Recruiting

Study on Tirofiban With Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY)

Branch Atheromatous Disease

China
Assistance Publique - Hôpitaux de Paris
BioMérieux

Recruiting

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter Trial (MULTI-EXA)

Acute Exacerbation of COPD

France
Seoul National University Bundang Hospital
Korea University; Ajou University School of Medicine; The Catholic University... and other collaborators

Recruiting

Comparisons of Metabolic Effect of Sleeve Gastrectomy With Duodenojejunal Bypass and Sleeve Gastrectomy (MEDUSA): A Multicenter Randomized Controlled Trial

Diabetes Mellitus, Type 2 | Surgical Procedures, Operative | Bariatric Surgery | Asians

Korea, Republic of
Taipei Veterans General Hospital, Taiwan

Recruiting

Sequencing and Combination of Mirabegron and TTNS in Overactive Bladder Syndrome: a Multicenter, Randomized, Open-label, Crossover Trial

Overactive Bladder Syndrome

Taiwan
Universidade do Oeste de Santa Catarina

Recruiting

The Use of ExPreS in the Weaning of Patients in Invasive Mechanical Ventilation: a Multicenter Randomized Clinical Trial

Respiratory Insufficiency

Brazil

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