Search clinical trials for: contractility

Total 85 results

Catharina Ziekenhuis Eindhoven
Maastricht University

Not yet recruiting

The Contractile Response of the Thoracic Aorta to Vasoactive Substances (AorticContract)

Human Thoracic Aorta Contractility

Netherlands
Samuel Lunenfeld Research Institute, Mount Sinai...

Recruiting

Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study

Postpartum Hemorrhage

Canada
Hackensack Meridian Health
Impulse Dynamics

Recruiting

Arrythmia Burden in Cardiac Contractility Modulation (CCM) (ABC)

Atrial Fibrillation | Arrythmia

United States
Samara State Medical University

Recruiting

Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML

Endothelial Dysfunction | Cardiotoxicity | Acute Myeloid Leukemia, Adult

Russian Federation
InCor Heart Institute
Impulse Dynamics; I2medi Comercial Medica LTDA

Recruiting

Cardiac Contractility Modulation in Chagas Heart Disease (FIX-Chagas)

Heart Failure | Chagas Cardiomyopathy | Systolic Dysfunction | Right Bundle Branch Block and Left Anterior Fascicular Block | Right Bundle Branch Block and Left Posterior Fascicular Block

Brazil
Samuel Lunenfeld Research Institute, Mount Sinai...

Recruiting

In Vitro Evaluation of Spontaneous and Oxytocin-induced Contractility of Pregnant Human Myometrium During Exposure to Dexmedetomidine

Postpartum Hemorrhage

Canada
University of Monastir

Recruiting

Non-invasive Left Ventricle Contractility dp/dt as Prognostic Marker in Chest Unit Patients (dp/dt)

Chest Pain

Tunisia
Ospedale C & G Mazzoni

Recruiting

Cardiac Contractility Modulation Therapy in Amyloid Cardiomyopathy Patients With Heart Failure (AMY-CCM)

Heart Failure | Amyloidosis Cardiac

Italy
Instituto Dante Pazzanese de Cardiologia

Recruiting

Percutaneous Revascularization in Infarction With Late Presentation and Absence of Viability: Effects on Left Ventricular Remodeling and Contractility

Percutaneous Coronary Intervention | Myocardial Dysfunction | STEMI - ST Elevation Myocardial Infarction

Brazil
Impulse Dynamics

Recruiting

Assessment of CCM in HF With Higher Ejection Fraction (AIM HIGHer)

Heart Failure | Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure | Heart Failure With Mid Range Ejection Fraction | Heart Failure With Moderately Reduced Ejection Fraction

United States
Monaldi Hospital

Recruiting

Subanalysis in Patients With CARDIoLAMinopathy Enrolled to REPORT-CCM Registry (CARDILAM-CCM)

Heart Failure | Lamin A/C Gene Mutation | Laminopathy

Italy
Monaldi Hospital

Recruiting

Observational and Prospective Registry on Cardiac Contractility Modulation (CCM) Therapy (REPORT-CCM)

Heart Failure, Systolic

Italy
University Hospitals Coventry and Warwickshire...
Coventry University

Recruiting

POWER Myocardial Fatigue Study: a Biomechanical Assessment of Contractility of Human Myocardium (POWER)

Heart Failure | Myocardial Dysfunction | Fatigue; Muscle, Heart | Exhaustion; Heart

United Kingdom
Rigshospitalet, Denmark

Recruiting

Using MRI in Patients With Non-dystrophic Myotonia to Access Muscle Contractility

Nondystrophic Myotonia | Paramyotonia Congenita

Denmark
University Hospital, Toulouse

Recruiting

Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone With the NOGA System (SCARPACE)

Myocardial Infarction

France
S. Andrea Hospital
Federico II University; Policlinico Hospital; Azienda Ospedaliera Bolognini di... and other collaborators

Recruiting

CCM Italian Registry

Heart Failure

Italy
Brigham and Women's Hospital

Recruiting

Comparison of Vasodilator Response of Inhaled Epoprostenol and Inhaled Nitric Oxide

Pulmonary Hypertension

United States
University of Leeds

Recruiting

Optimising Pacing for Contractility 2 (OPT-cont 2)

Heart Failure, Systolic | Pacemaker

United Kingdom
University of Giessen

Not yet recruiting

RV Systolic and Diastolic Function and Contractile Reserve Under Acute Exercise and in Response to Chronic Exercise-based Rehabilitation (Reserve)

Heart Failure | Pulmonary Hypertension | Right Heart Failure | Contractility | RV-arterial Coupling

Germany
Samuel Lunenfeld Research Institute, Mount Sinai...

Recruiting

Effects of Ephedrine, Phenylephrine, Norepinephrine and Vasopressin on Contractility of Human Myometrium and Umbilical Vessels: An In-vitro Study

Hypotension

Canada
Impulse Dynamics

Recruiting

Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy (PAS)

Heart Failure

United States
Intermountain Health Care, Inc.
Beth Israel Deaconess Medical Center; Montefiore Medical Center; Wake Forest... and other collaborators

Recruiting

Study of Treatment's Echocardiographic Mechanisms

Sepsis

United States
University of Nottingham

Recruiting

The Accuracy of Endometrial Ultrasound to Predict Implantation

Infertility, Subfertility

United Kingdom
Cardionomic Inc.

Completed

Cardionomic STOP-ADHF Study

Acute Decompensated Heart Failure

United States, Belgium, Netherlands, Panama
Cardionomic Inc.

Completed

The STIM-ADHF Study

Acute Decompensated Heart Failure

Hungary, Poland, Slovakia
Brugmann University Hospital

Completed

Validation of Kinocardiography, New Technology for Cardiac Linear and Torsional Contractility Measurement, to Assess Heart Failure Patient With Low Ejection Fraction

Impaired Left Ventricular Ejection Fraction

Belgium
University of Colorado, Denver

Terminated

Cardiac Output in Heart Failure Patients With Mechanical Pumps

Heart Failure, Systolic | Mechanical Circulatory Support | Cardiovascular Hemodynamics

United States
Karolinska Institutet

Suspended

The ADRB3 Receptor in Pregnancy

Pregnancy Complications

Sweden
Samuel Lunenfeld Research Institute, Mount Sinai...

Completed

In Vitro Optimization of Oxytocin-induced Myometrial Contractility by Propranolol

Postpartum Hemorrhage

Canada
Universitaire Ziekenhuizen KU Leuven

Completed

Behaviour of Tricuspid Valve Regurgitation in Volume and/or Pressure Loaded Right Heart

Tricuspid Valve Insufficiency

Belgium
St. Joseph's Hospital and Medical Center, Phoenix

Withdrawn

Uterine Electrical Activity Before and After Progesterone Treatment for Preterm Labor

Preterm Labor

United States
Samuel Lunenfeld Research Institute, Mount Sinai...

Completed

Spontaneous and Oxytocin-induced Contractility After Exposure to Intravenous Anesthetic Agents: an In-vitro Study in Human Myometrium

Postpartum Hemorrhage

Canada
National Medical Research Center for Cardiology...
Ministry of Health, Russian Federation

Completed

Cardiac Contractility Modulation in Patients With Chronic Heart Failure and the Various Forms of Atrial Fibrillation

Heart Failure | Atrial Fibrillation | Left Ventricular Ejection Fraction

Russian Federation
University of Luebeck

Terminated

Effects of Acutely Elevated Afterload on Left Ventricular Contractility and Relaxation (ANREP-EF)

Heart Failure

Germany
Alexandria University

Completed

Role of Echocardiography in Guiding Fluid Therapy in Shocked Patients With Impaired Cardiac Contractility in Emergency Department

Shock

Egypt
University of Southern Denmark
Odense University Hospital; Fonden til Lægevidenskabens Fremme; Sygehus Lillebaelt and other collaborators

Completed

Muscle Strain in Multiple Sclerosis Patients Measured by Ultrasound Speckle Tracking Technique (MUST)

Multiple Sclerosis

Denmark
Chinese University of Hong Kong

Withdrawn

Stopping Biological Therapy in PCD Study

MRI | Perianal Crohn Disease | Biological Therapy

Hong Kong
Impulse Dynamics

Terminated

Continued Access Protocol for the Evaluation of the OPTIMIZER Smart System (FIX-HF-5CA)

Heart Failure | Congestive Heart Failure | CHF | Chronic Heart Disease

United States
University Hospital, Bordeaux

Completed

Speckle-Tracking and Volume Expansion (FLUID-STRAIN)

Volume Expansion | Left Ventricular Contractility

France
Impulse Dynamics

Completed

Evaluate Safety and Efficacy of the OPTIMIZER® System in Subjects With Moderate-to-Severe Heart Failure: FIX-HF-5C (FIX-HF-5C)

NYHA Class III Heart Failure | NYHA Class IV Heart Failure

United States, Germany, Czechia
Azienda Sanitaria-Universitaria Integrata di Udine

Active, not recruiting

Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in the Positive COVID-19 Patient

COVID-19 Pneumonia | Diaphragm Disease

Italy
Cytokinetics

Completed

COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF)

Chronic Heart Failure | Pharmacokinetics | Left Ventricular Systolic Dysfunction | Left Ventricular Ejection Fraction | Modified Release Oral Formulation | History of Chronic Heart Failure | Echocardiogram

United States, Canada, Italy, Netherlands, United Kingdom, Belgium, Czechia, Australia, Hungary, Poland, Bulgaria, Lithuania, Germany
The Hospital for Sick Children

Terminated

The Assessment of Right Ventricular Contractility in Response to Sildenafil

Hypertension

Canada
Asan Medical Center

Completed

The Long Term Effects of Alfuzosin(Xatral XL) in Lower Urinary Tract Symptoms(LUTS)/BPH Patients

BPH
University of Castilla-La Mancha

Completed

Effect of Dry Needling on Muscle Mechanical Properties and Muscle Contractility in Latent Trigger Points

Trigger Point Pain, Myofascial

Spain
Impulse Dynamics

Terminated

Cardiac Contractility Modulation (CCM) Therapy in Subjects With Medically Refractory Heart Failure (IMPULSE-HF)

Heart Failure

Sweden, Austria, Germany, Poland
Impulse Dynamics

Completed

Evaluation of the Safety and Effectiveness of the OPTIMIZER System in Subjects With Heart Failure: FIX-HF-5

Heart Failure, Congestive

United States
University of Leeds

Completed

Optimising Pacemaker Therapy for Contractility (OPT-C)

Chronic Heart Failure

United Kingdom
King's College Hospital NHS Trust

Completed

The Impact of the pH on Cardiac Function in the Critically Ill Patient

Acidosis | Acid Base Disorder | Cardiac; Deficiency

United Kingdom
Oxytone Bioscience BV

Terminated

Compare Efficacy of Oxytocin Administrations on Postpartum Uterine Contractility

Post Partum Haemorrhage

Sweden

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