- ICH GCP
- Registr klinických studií v USA
- Klinická studie NCT06306976
Predicting Fascial Closure in Midline Incisional Hernias Using Shear-Wave Elastography
This clinical trial investigates the use of shear-wave elastography (SWE) as a predictive tool for fascial closure in patients with midline incisional hernias. The study aims to assess abdominal wall muscle elasticity preoperatively and correlate these measurements with surgical outcomes. By evaluating the rectus abdominis, external oblique, internal oblique, and transversus abdominis muscles, researchers hope to improve surgical planning and reduce complications.
Study Objectives:
- Measure abdominal wall muscle elasticity using SWE in patients with varying hernia complexities.
- Correlate SWE findings with the extent of myofascial release (MFR) required for fascial closure.
- Compare SWE results with intraoperative tension measurements using a spring-tensiometer.
Methodology:
The study includes 70 participants divided into three groups: patients with midline incisional hernias (study group) and two control groups (healthy volunteers and patients undergoing elective midline laparotomy). All participants will undergo ultrasound imaging with SWE, while the study group and one control group will also receive surgical intervention.
Key Procedures:
- Ultrasound imaging with SWE at specific abdominal landmarks
- Open retromuscular hernia repair with mesh reinforcement for study patients
- Tensiometry during surgery to measure closure tension
Potential Impact:
This research could revolutionize preoperative planning for hernia repairs by providing objective measurements of abdominal wall compliance. If successful, SWE may become a standard tool for predicting surgical outcomes and tailoring operative approaches to individual patient anatomy.
Připravované klinické studie
-
NCT06145984Nábor
-
NCT07649083Zatím nenabírámeCévní přístup | Arteriovenózní píštěle | Komplikace hemodialýzy | Konečné stadium selhání ledvin, hemodialýza | Pacienti na hemodialýze
-
NCT07649096Zatím nenabíráme
-
NCT07649109NáborSrdeční arytmie | Subklinická fibrilace síní
-
NCT07649122Zatím nenabíráme
-
NCT07649135Zatím nenabírámeMrtvice | Cévní mozková příhoda | Hemoragická mrtvice
-
NCT07649148NáborSrdeční selhání | Srdeční selhání třídy NYHA III | NYHA Class II Heart Failure
-
NCT07649161Nábor
-
NCT07649174Zatím nenabírámeRakovina děložního hrdla
-
NCT07649200Zatím nenabírámeSolidní nádory
-
NCT07649239NáborAugmentace měkkých tkání u zubních implantátů | Pojivový tkáňový štěp | Měkká tkáň | PRF | Peri-implantát zdraví