- ICH GCP
- Registr klinických studií v USA
- Klinická studie NCT07659340
Effectiveness of Immersive and Embodied Enhancement Via "Virtual Reality" on the Sustainability of Hand Hygiene Compliance: School-based RCT With 10-month Follow-up (HKU-VR-2026)
This study aims to evaluate the effectiveness of a VR intervention on teaching handwashing skills which are promoted by the Centre for Health Protection, Department of Health, HKSAR. A 7-step handwashing approach will be taught through a customized VR game in secondary schools in Hong Kong. Participant's handwashing skills and prolonged effects on handwashing habits and hygiene level will be assessed.
The main questions it aims to answer are:
- Does an intervention of our VR handwashing game enhance handwashing skills amongst junior secondary students?
- What are the factors hinder or enhance students' learning of handwashing skills in the intervention?
Participating students will be assigned into 3 groups. Each group will receive two sessions of educational training with different kinds of intervention throughout one school year (9 months). The first intervention group will participate in two VR-game sessions on handwashing skill; the second intervention group will participate in one VR-game session and one video session about handwashing; the baseline group will participate in two sessions of other VR activities unrelated to hand hygiene and view a handwashing skill poster. The research will compare the handwashing performance between the three groups.
Participants will:
- participate into a VR handwashing game intervention, or a video-based intervention, or placebo VR activities as stated hereinafter;
- perform handwashing in the VR game, and their hand-motion data will be captured;
- participate a UV lighting test after handwashing away fluorescent lotion; and,
- fill up questionnaires
Přehled studie
Postavení
Podmínky
Detailní popis
Schools are often the site of infection outbreaks, including COVID-19, influenza and other infectious diseases. COVID-19 pandemic has accelerated the need to enhance hygiene levels at primary and secondary schools and, specifically, nurturing and enforcing students' regular handwashing practices is one of the key components of a preventive strategy to reduce the transmission of infectious illnesses. Meanwhile, Virtual Reality (VR) intervention has been shown to be an efficacious tool for behavioural change. It manipulates an array of behavioural and environmental variables to construct an immersive virtual environment for changing certain human behaviours. VR handwashing education system may be more helpful than conventional verbal explanation in encouraging school children to wash their hands thoroughly, especially overcoming difficult to wash areas including wrists. Nevertheless, a school-based VR intervention on handwashing education is lacked in Hong Kong.
Objective:
This study aims to evaluate the effectiveness of a VR intervention on teaching handwashing skills which are promoted by the Centre for Health Protection, Department of Health, HKSAR. A 7-step handwashing approach will be taught through a customized VR game in secondary schools in Hong Kong. Participant's handwashing skills and prolonged effects on handwashing habits and hygiene level will be assessed.
Methods:
A 3-arm randomized controlled trial will be adopted. About 500 students will be assigned into 3 groups which will be randomly assigned on class-basis. Each group will receive two sessions of educational training with different kinds of intervention throughout one school year (9 months). The first intervention group will participate in two VR-game sessions on handwashing skill; the second intervention group will participate in one VR-game session and one video session about handwashing; the baseline group will participate in two sessions of other VR activities unrelated to hand hygiene and view a handwashing skill poster. Comparison of pre- and post-intervention hand-images of participants will serve as primary measurement. Ultraviolet-sensitive fluorescent lotion will be applied to the participants' hands and digital photos will be taken under UV lighting environment. Image comparisons will adopt quantitative method of calculating the percentage of fluorescent pixels over total hand areas. Post-intervention hand-images will be collected 3 months after the second intervention in order to capture any prolonged effect on handwashing over the whole intervention period. The secondary measures will be deployed through pre-invention, immediate post-intervention and follow-up (3 months after intervention) surveys. The survey will comprise scales measuring self-efficacy, knowledge on hand hygiene, handwashing habits and intentions, attitudes, subjective norms, and perceived behavioral control, VR embodiment and VR experience.
Results:
The project has already commenced in March 2026. The data collection period of the randomized controlled trial will be started from Sep 2026 and will end in May 2027. Data will be analyzed during June and August 2027, and the results are expected to be released in September 2027.
Conclusion:
This study contributes to existing knowledge about infection prevention strategy through VR game as well as the hand hygiene of the student population in Hong Kong and elsewhere. The study fills a number of research gaps in the field by (1.) developing evidence-based and executable VR hand hygiene programmes in school settings; (2.) addressing the ill-solved sustainability issue of hand hygiene intervention effects; (3.) identifying factors underlying the pathway of behavioural changes on hand hygiene and issues related to barriers to change, and (4.) identifying handwashing patterns through hand motion data shaping the hand hygiene level. The experiences and results from this VR game project can be also transferable to develop other programme regarding public health by adopting VR devices.
Typ studie
Zápis (Odhadovaný)
Fáze
- Nelze použít
Kontakty a umístění
Studijní kontakt
- Jméno: Siu-lun Chow, PhD
- Telefonní číslo: 852+3917 1155
- E-mail: chowcass@hku.hk
Studijní místa
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-
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Hong Kong, Hongkong
- Nábor
- School of Future Media, The University of Hong Kong
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Kontakt:
- King-wa Fu, Professor
- Telefonní číslo: 852+3917 1643
- E-mail: kwfu@hku.hk
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Vrchní vyšetřovatel:
- King-wa Fu, Professor
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-
Kritéria účasti
Kritéria způsobilosti
Věk způsobilý ke studiu
- Dítě
Přijímá zdravé dobrovolníky
Popis
Inclusion Criteria:
- Hong Kong secondary school students studying junior forms
Exclusion Criteria:
-
Studijní plán
Jak je studie koncipována?
Detaily designu
- Primární účel: Prevence
- Přidělení: Randomizované
- Intervenční model: Paralelní přiřazení
- Maskování: Dvojnásobek
Zbraně a zásahy
Skupina účastníků / Arm |
Intervence / Léčba |
|---|---|
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Experimentální: Intervention 1
Participants who attend two VR game sessions
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The intervention will be a VR game taught about the '7-Steps approach' of hand-washing promoted by Centre for Health Protection, HKSAR. The game is comprised of two parts: Training Mode and Challenge Mode. In Training Mode, students will be guided with text and voice feedback. A pair of 'ghost hands' will demonstrate what to do. Students follow the movements of the 'ghost hands' to complete the handwashing tasks. In the Challenge Mode, students are requested to perform all the steps at once by their own memory, hints will be given only when they encounter setback in an assigned duration. Trained facilitators will teach participants how to use the VR devices and provide briefing sessions on how to play the game. For the Intervention Group 1, they will play the game in two separate sessions (about 4 months between the two sessions). |
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Experimentální: Intervention 2
Participants who attend one VR game session and one video-based education session
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For Intervention Group 2, participants will attain one VR game session and 1 video-instructed session.
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Žádný zásah: Baseline Group
Participants who attend two non-hand hygiene related VR activity sessions
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Co je měření studie?
Primární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
|---|---|---|
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Hand-imaging Data
Časové okno: Hand-imaging data will only be collected before the 1st intervention and at the end of the data collection period (about 9 months after the 1st intervention).
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Ultraviolet-sensitive fluorescent lotion (e.g., Glo Germ™) will be applied on participants' hands thoroughly to simulate full contamination (e.g., germs and pathogens) on hands.
Then participants wash their hands.
The areas where lotion has been washed out are considered as 'decontaminated'.
The participants will put their washed hands in a black box with an Ultraviolet-A (365nm) lighting system.
Both palms and dorsa of left and right hands will be photographed.
|
Hand-imaging data will only be collected before the 1st intervention and at the end of the data collection period (about 9 months after the 1st intervention).
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Sekundární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
|---|---|---|
|
Knowledge on Hand Hygiene and Handwashing
Časové okno: This measurement will be collected through questionnaire pre-intervention, immediately after 1st intervention, after 2nd intervention (5 months after 1st intervention) and in the follow-up survey (9 months after 1st intervention).
|
As this study is focused on handwashing skills and steps, questionnaires on this field are usually customized for the context of the research (i.e., steps and skills can be differed between studies).
As our interventions mainly teach about the 7-handwashing steps suggested by the Centre for Health Protection, Department of Health, HKSAR, five questions will be developed to assess participants' knowledge of the handwashing procedures.
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This measurement will be collected through questionnaire pre-intervention, immediately after 1st intervention, after 2nd intervention (5 months after 1st intervention) and in the follow-up survey (9 months after 1st intervention).
|
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Handwashing Habit
Časové okno: This measurement will be collected through questionnaire pre-intervention, immediately after 1st intervention, after 2nd intervention (5 months after 1st intervention) and in the follow-up survey (9 months after 1st intervention).
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Two components on handwashing habit will be measured frequency of handwashing.
Five items on how often the participants cleaned their hands on five different scenarios (before meal, after using washroom, after taking public transportation, after arriving at the school and after going back home) will be asked to measure the frequency of handwashing (5-point scale from 'never' to 'always'.
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This measurement will be collected through questionnaire pre-intervention, immediately after 1st intervention, after 2nd intervention (5 months after 1st intervention) and in the follow-up survey (9 months after 1st intervention).
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Attitude and Intention
Časové okno: This measurement will be collected through questionnaire pre-intervention, immediately after 1st intervention, after 2nd intervention (5 months after 1st intervention) and in the follow-up survey (9 months after 1st intervention).
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The attitude on automaticity of handwashing habit will be measured by the Self-Report Behaviour Automaticity Index (SRBAI), which has already been modified and validated into four items regarding handwashing in another study.
The sample item is 'Hand washing is something I start doing before I realise I'm doing it'.
The four items are measured on a 7-point Likert scale, ranging from 1 ("does not apply to me at all") to 7 ("completely applies to me").
Behavioural intention will be measured by a single item : "In my daily routine, I want to perform hand hygiene as correctly as possible" on a 7-point Likert scale.
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This measurement will be collected through questionnaire pre-intervention, immediately after 1st intervention, after 2nd intervention (5 months after 1st intervention) and in the follow-up survey (9 months after 1st intervention).
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Spolupracovníci a vyšetřovatelé
Sponzor
Publikace a užitečné odkazy
Obecné publikace
- Eichel VM, Brandt C, Brandt J, Jabs JM, Mutters NT. Is virtual reality suitable for hand hygiene training in health care workers? Evaluating an application for acceptability and effectiveness. Antimicrob Resist Infect Control. 2022 Jun 25;11(1):91. doi: 10.1186/s13756-022-01127-6.
- Stuart JP, Gannon PR, Dotto VR, Regina R, Mumma JM. Visualizing the WHO "My Five Moments for Hand Hygiene," framework: A virtual reality training program for improving hand hygiene adherence among nurses. Am J Infect Control. 2025 May;53(5):576-581. doi: 10.1016/j.ajic.2025.01.007. Epub 2025 Jan 15.
- Birrenbach T, Zbinden J, Papagiannakis G, Exadaktylos AK, Muller M, Hautz WE, Sauter TC. Effectiveness and Utility of Virtual Reality Simulation as an Educational Tool for Safe Performance of COVID-19 Diagnostics: Prospective, Randomized Pilot Trial. JMIR Serious Games. 2021 Oct 8;9(4):e29586. doi: 10.2196/29586.
- Sin CS, Rochelle TL. Using the theory of planned behaviour to explain hand hygiene among nurses in Hong Kong during COVID-19. J Hosp Infect. 2022 May;123:119-125. doi: 10.1016/j.jhin.2022.01.018. Epub 2022 Feb 3.
- O'Boyle CA, Henly SJ, Larson E. Understanding adherence to hand hygiene recommendations: the theory of planned behavior. Am J Infect Control. 2001 Dec;29(6):352-60. doi: 10.1067/mic.2001.18405.
- Srigley JA, Corace K, Hargadon DP, Yu D, MacDonald T, Fabrigar L, Garber G. Applying psychological frameworks of behaviour change to improve healthcare worker hand hygiene: a systematic review. J Hosp Infect. 2015 Nov;91(3):202-10. doi: 10.1016/j.jhin.2015.06.019. Epub 2015 Aug 4.
- Gasteiger N, van der Veer SN, Wilson P, Dowding D. Virtual reality and augmented reality smartphone applications for upskilling care home workers in hand hygiene: a realist multi-site feasibility, usability, acceptability, and efficacy study. J Am Med Inform Assoc. 2023 Dec 22;31(1):45-60. doi: 10.1093/jamia/ocad200.
- Galvan Debarba H, Bovet S, Salomon R, Blanke O, Herbelin B, Boulic R. Characterizing first and third person viewpoints and their alternation for embodied interaction in virtual reality. PLoS One. 2017 Dec 27;12(12):e0190109. doi: 10.1371/journal.pone.0190109. eCollection 2017.
- Asadzadeh A, Samad-Soltani T, Rezaei-Hachesu P. Applications of virtual and augmented reality in infectious disease epidemics with a focus on the COVID-19 outbreak. Inform Med Unlocked. 2021;24:100579. doi: 10.1016/j.imu.2021.100579. Epub 2021 Apr 27.
- Mira J, Gonzalez M, Villalba C, Guerra L, Ramirez-Moya Y, Hernandez J, Moya O, Pineda L, Perez-Esteve C. Improving Hand Hygiene Skills Using Virtual Reality: Quasi-Experimental Study. J Med Internet Res. 2025 Oct 7;27:e78882. doi: 10.2196/78882.
- The Centre for Health Protection, Department of Health, HKSAR. Proper Hand Hygiene. The Centre for Health Protection, Department of Health, HKSAR; 2026. https://www.chp.gov.hk/en/healthtopics/content/460/19728.html
- Faruk Karabulut O, Celikcan U, Ellahi B, Dikmen D. Training of food handlers on handwashing using a virtual reality environment is more effective than traditional training approaches in a randomized trial. Int J Environ Health Res. 2025 Aug;35(8):2067-2078. doi: 10.1080/09603123.2024.2425781. Epub 2024 Nov 10.
- Allegranzi B, Gayet-Ageron A, Damani N, Bengaly L, McLaws ML, Moro ML, Memish Z, Urroz O, Richet H, Storr J, Donaldson L, Pittet D. Global implementation of WHO's multimodal strategy for improvement of hand hygiene: a quasi-experimental study. Lancet Infect Dis. 2013 Oct;13(10):843-51. doi: 10.1016/S1473-3099(13)70163-4. Epub 2013 Aug 23.
- World Health Organization. WHO Guidelines on Hand Hygiene in Health Care. World Health Organization. https://www.who.int/publications/i/item/9789241597906.com
- Hoyle E, Davies H, Bourhill J, Roberts N, Lee JJ, Albury C. Effectiveness of hand-hygiene interventions in reducing illness-related absence in educational settings in high income countries: systematic review and behavioural analysis. J Public Health. 2025;33(3):659-670. doi:10.1007/s10389-023-02044-7
- Willmott M, Nicholson A, Busse H, MacArthur GJ, Brookes S, Campbell R. Effectiveness of hand hygiene interventions in reducing illness absence among children in educational settings: a systematic review and meta-analysis. Arch Dis Child. 2016 Jan;101(1):42-50. doi: 10.1136/archdischild-2015-308875. Epub 2015 Oct 15.
- World Health Organization. Progress on drinking water, sanitation and hygiene in schools: Special focus on COVID-19. 2020a [cited 2026 June 15]. Available from https://data.unicef.org/resources/progress-on-drinking-water-sanitation-and-hygiene-in schools- special-focus-on-covid-19/
- Jatrana S, Hasan MM, Mamun AA, Fatima Y. Global Variation in Hand Hygiene Practices Among Adolescents: The Role of Family and School-Level Factors. Int J Environ Res Public Health. 2021 May 7;18(9):4984. doi: 10.3390/ijerph18094984.
- Miron O, Yu KH, Wilf-Miron R, Kohane I, Davidovitch N. COVID-19 infections following physical school reopening. Arch Dis Child. 2021 Jul 19;106(8):e34. doi: 10.1136/archdischild-2020-321018. No abstract available.
Termíny studijních záznamů
Hlavní termíny studia
Začátek studia (Aktuální)
Primární dokončení (Odhadovaný)
Dokončení studie (Odhadovaný)
Termíny zápisu do studia
První předloženo
První předloženo, které splnilo kritéria kontroly kvality
První zveřejněno (Aktuální)
Aktualizace studijních záznamů
Poslední zveřejněná aktualizace (Aktuální)
Odeslaná poslední aktualizace, která splnila kritéria kontroly kvality
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