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Lung-MAP: Biomarkør-målrettet andenlinje-terapi til behandling af patienter med tilbagevendende trin IV planocellulær lungekræft

30. maj 2023 opdateret af: SWOG Cancer Research Network

En biomarkør-drevet masterprotokol for tidligere behandlet planocellulær lungekræft (lungekort)

Denne screening og multi-sub-studie randomiserede fase II/III-forsøg vil etablere en metode til genomisk screening af lignende store cancerpopulationer efterfulgt af tildeling og samtidig tildeling til en multi-sub-studie hybrid ?Master Protocol? (S1400). Typen af ​​kræftegenskab (biomarkør) vil afgøre, til hvilken underundersøgelse, inden for denne protokol, en deltager vil blive tildelt til at sammenligne ny målrettet cancerterapi, designet til at blokere vækst og spredning af cancer, eller kombinationer til standardbehandling med det ultimative mål at være i stand til at godkende nye målrettede terapier i denne indstilling. Derudover indeholder protokollen en ?ikke-match? delstudie, som vil omfatte alle screenede patienter, der ikke er kvalificerede til nogen af ​​de biomarkør-drevne delstudier. Dette delstudie vil sammenligne en non-match terapi med standardbehandling også med målet om godkendelse.

Studieoversigt

Status

Afsluttet

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

PRIMÆRE MÅL:

Screeningskomponent:

I. At etablere en National Clinical Trials Network (NCTN) mekanisme til genomisk screening af store, men homogene kræftpopulationer og efterfølgende tildeling og samtidig tildeling til en multi-sub-undersøgelse ?Master Protocol.? II. At evaluere screeningssuccesraten defineret som procentdelen af ​​screenede patienter, der tilmelder sig et terapeutisk delstudie.

Delstudiespecifikke mål:

Design #1: Fase II/III Design:

III. At evaluere, om der er tilstrækkelig evidens til at fortsætte til fase III-komponenten i delstudiet ved at sammenligne investigator-vurderet progressionsfri overlevelse (IA-PFS) mellem undersøgelsesterapi versus standardterapi (SoC) hos patienter med refraktær pladecelle i fremskreden stadium carcinom (SCCA) i lungen. (Fase II) IV. For at bestemme, om der er både en statistisk og klinisk betydningsfuld forskel i IA-PFS blandt refraktær SCCA i fremskreden stadium i lungen randomiseret til at modtage undersøgelsesterapi versus SoC. (Fase III) V. At sammenligne overordnet overlevelse (OS) hos patienter med refraktær SCCA i fremskreden stadium i lungen randomiseret til undersøgelsesterapi versus SoC. (Fase III)

Design #2: Fase II efterfulgt af Fase III (sekventiel Fase II til Fase III):

VI. At evaluere den objektive svarprocent (bekræftet og ubekræftet, fuldstændig og delvis). (Fase II) VII. For at bestemme, om der er både en statistisk og klinisk betydningsfuld forskel i IA-PFS blandt refraktær SCCA i fremskreden stadium i lungen randomiseret til at modtage undersøgelsesterapi versus SoC. (Fase III) VIII. At sammenligne overordnet overlevelse (OS) hos patienter med fremskredent stadium af refraktær SCCA i lungen randomiseret til undersøgelsesterapi versus SoC. (Fase III)

SEKUNDÆRE MÅL:

Delstudiespecifikke mål:

Design #1: Fase II/III Design:

I. At sammenligne responsrater (bekræftede og ubekræftede, fuldstændige og delvise responser) blandt patienter randomiseret til at modtage undersøgelsesterapi versus SoC. (Fase II) II. At evaluere hyppigheden og sværhedsgraden af ​​toksiciteter forbundet med forsøgsbehandling versus SoC. (Fase II) III. At evaluere varigheden af ​​respons (DoR) blandt patienter, der opnår en komplet respons (CR) eller en delvis respons (PR) ved responsevalueringskriterier i solide tumorer (RECIST) (1.1). (Fase II) III. At sammenligne responsraterne (bekræftet og ubekræftet, fuldstændig og delvis) blandt patienter, der er randomiseret til at modtage undersøgelsesterapi versus SoC. (Fase III) IV. At evaluere hyppigheden og sværhedsgraden af ​​toksiciteter forbundet med forsøgsbehandling versus SoC. (Fase III)

Design #2: Fase II efterfulgt af Fase III (sekventiel Fase II til Fase III):

V. At evaluere PFS og OS med undersøgelsesterapi. (Fase II) VI. At evaluere DoR blandt patienter, der opnår en CR eller PR (bekræftet og ubekræftet) af RECIST 1.1. (Fase II) VII. At evaluere hyppigheden og sværhedsgraden af ​​toksiciteter forbundet med forsøgsbehandling. (Fase II) VIII. At sammenligne responsraterne (bekræftet og ubekræftet, fuldstændig og delvis) blandt patienter, der er randomiseret til at modtage undersøgelsesterapi versus SoC. (Fase III) IX. At evaluere hyppigheden og sværhedsgraden af ​​toksiciteter forbundet med forsøgsbehandling versus SoC. (Fase III)

TERTIÆRE MÅL:

I. At evaluere behandlingsarmens randomiseringsacceptrate (TARAR) inden for hver behandlingsarm af hvert delstudie defineret som procentdelen af ​​patienter, der er randomiseret til en behandlingsarm, som modtager enhver protokolbehandling. (Design #1: Fase II/III Design) II. At identificere yderligere prædiktive tumor/blod-biomarkører, der kan modificere respons eller definere resistens over for den målrettede terapi (TT)/målrettet terapi-kombination (TTC) ud over den valgte biomarkør for biomarkør-drevne delstudier.

III. At evaluere potentielt prædiktive biomarkører for non-match terapi (NMT) i non-match studierne.

IV. At identificere potentielle resistensbiomarkører ved sygdomsprogression. V. At etablere et vævs-/bloddepot fra patienter med refraktær SCCA i lungen.

OVERSIGT: Patienter tildeles en biomarkør-drevet målrettet terapi fase II undersøgelse. Hvis den observerede målresponsrate vurderes at være tilstrækkelig, fortsætter patienterne til et randomiseret fase III-forsøg og randomiseres til biomarkør-drevet målrettet terapi eller standardbehandling.

S1400A: (LUKKET FOR AKKURAT 12/18/2015) Patienter med tumorer, der ikke matcher en af ​​de aktuelt aktive lægemiddel-biomarkør-kombinationer eller ikke opfyldte berettigelseskravene for det biomarkørdrevne delstudie, tildeles arm I. Ved tegn på progression efter seponering af 12 måneders behandling, kan patienterne genoptage behandlingen i op til 12 måneder med de samme behandlingsretningslinjer som følges i den indledende 12-måneders behandlingsperiode (arm III).

ARM I: (LUKKET FOR PERSONLIG 12/18/2015) Patienter modtager anti-B7H1 monoklonalt antistof MEDI4736 intravenøst ​​(IV) over 60 minutter på dag 1. Behandlingen gentages hver 14. dag i 12 måneder i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II (LUKKET FOR OPDATERING 4/2015): Patienter får docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #2 22/4/15)

ARM III: For patienter tildelt til arm 1, MEDI4736: Ved tegn på progression efter seponering af 12 måneders behandling, kan patienter genoptage behandlingen med arm 3, MEDI4736 i op til 12 måneder med de samme behandlingsretningslinjer fulgt i løbet af de første 12 måneder behandlingsperiode. Patienter vil kun kunne genoptage behandlingen én gang; således vil der maksimalt være tilladt to 12-måneders perioder. Patienter får anti-B7H1 monoklonalt antistof MEDI4736 intravenøst ​​(IV) over 60 minutter på dag 1. Behandlingen gentages hver 14. dag i 12 måneder i fravær af sygdomsprogression eller uacceptabel toksicitet.

S1400B (LUKKET FOR PERSONLIG 12/12/2016): Patienter med tumorer positive for phosphoinositide 3-kinase (PI3KCA) tildeles Arm I. Patienter, der i øjeblikket er på Arm 2, docetaxel vil få mulighed for at omregistrere sig til Arm 3, GCD-0032 efter sygdomsprogression på nuværende behandling (arm III).

ARM I: Patienterne får taselisib oralt (PO) dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II (LUKKET FOR OPDATERING 12/18/2015): Patienter får docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #3 18/12/2015)

ARM III: Genregistreringsbehandling med GDC-0032 (Taselisib) Efter progression kan patienter i arm 2 være berettiget til genregistrering for at modtage GDC-0032. Patienterne får taselisib oralt (PO) dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

S1400C (LUKKET FOR PERSONLIG 09/01/2016): Patienter med tumorer positive for cyclinafhængig kinase 4 (CDK4), cyclin D1 (CCND1), cyclin D2 (CCND2) og cyclin D3 (CCND3) tildeles arm I. Patienter i øjeblikket på arm 2, vil docetaxel få mulighed for at omregistrere sig til arm 3, palbociclib, efter sygdomsprogression på nuværende behandling (arm III).

ARM I: Patienter modtager palbociclib PO på dag 1-21. Kurser gentages hver 28. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II (LUKKET FOR OPDATERING 12/18/2015): Patienter får docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #3 18/12/2015)

ARM III: Genregistreringsbehandling med Palbociclib. Efter progression kan patienter i arm 2 være berettiget til genregistrering for at modtage palbociclib. Patienter modtager palbociclib PO på dag 1-21. Kurser gentages hver 28. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

S1400D (LUKKET FOR PERSONLIG 31/10/2016): Patienter med tumorer, der er positive for fibroblast vækstfaktor receptor (FGFR) 1, FGFR2 og FGFR3, tildeles arm I. Patienter i arm 2, docetaxel vil få mulighed for at gentage -registrer til arm 3, AZD4547, efter sygdomsprogression på nuværende behandling (arm III).

ARM I: Patienter modtager FGFR-hæmmer AZD4547 PO BID på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II (LUKKET FOR OPDATERING 12/18/2015): Patienter får docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #3 18/12/2015)

ARM III: Genregistreringsbehandling med AZD4547. Efter progression kan patienter i arm 2 være berettiget til genregistrering for at modtage AZD4547. Patienter får FGFR-hæmmer AZD4547 PO BID på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

S1400E (LUKKET FOR AKKURAT 25/11/2014): Patienter med tumorer positive for met proto-onkogen (MET) randomiseres til 1 ud af 2 behandlingsarme. (permanent lukket for optjening den 25/11/14)

ARM I: Patienterne får rilotumumab IV på dag 1 og erlotinib hydrochlorid PO dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II: Patienter får erlotinib hydrochlorid PO dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

S1400F: Patienter med sygdomsprogression under eller efter tidligere anti-PD-1 eller anti-PD-L1 antistof monoterapi som deres seneste behandlingslinje modtager durvalumab (IV over 60 minutter) og tremelimumab (IV over 60 minutter) på dag 1 for forløb 1-4 og durvalumab IV alene på dag 1 af kursus 5 og efterfølgende forløb indtil sygdomsprogression eller uacceptabel toksicitet. Kurser gentages hver 28. dag.

S1400G: Patienter med tumorer positive for homolog rekombinationsreparationsmangel modtager talazoparib PO dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

S1400I: Patienter med tumorer, der ikke matcher en af ​​de aktuelt aktive lægemiddel-biomarkør-kombinationer eller ikke opfyldte berettigelseskravene til det biomarkørdrevne delstudie, randomiseres til 1 ud af 2 behandlingsarme.

ARM I: Patienterne får nivolumab IV over 30 minutter på dag 1 og ipilimumab IV over 60 minutter på dag 1 i hver tredje behandling. Kurser gentages hver 14. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II: Patienter får nivolumab IV over 30 minutter på dag 1. Kurser gentages hver 14. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.

Efter afsluttet undersøgelsesbehandling følges alle patienter periodisk i op til 3 år fra datoen for screeningsregistrering.

Undersøgelsestype

Observationel

Tilmelding (Faktiske)

1864

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

  • Canada
    • Alberta
      • Edmonton, Alberta, Canada, T6G 1Z2
        • Cross Cancer Institute
    • Ontario
      • Hamilton, Ontario, Canada, L8V 5C2
        • Juravinski Cancer Centre at Hamilton Health Sciences
      • Ottawa, Ontario, Canada, K1H 8L6
        • Ottawa Hospital and Cancer Center-General Campus
      • Toronto, Ontario, Canada, M5G 2M9
        • University Health Network-Princess Margaret Hospital
    • Saskatchewan
      • Regina, Saskatchewan, Canada, S4T 7T1
        • Allan Blair Cancer Centre
      • Saskatoon, Saskatchewan, Canada, S7N 4H4
        • Saskatoon Cancer Centre
  • Forenede Stater
    • Alabama
      • Birmingham, Alabama, Forenede Stater, 35233
        • University of Alabama at Birmingham Cancer Center
    • Alaska
      • Anchorage, Alaska, Forenede Stater, 98508
        • Anchorage Associates in Radiation Medicine
      • Anchorage, Alaska, Forenede Stater, 99508
        • Alaska Breast Care and Surgery LLC
      • Anchorage, Alaska, Forenede Stater, 99508
        • Alaska Oncology and Hematology LLC
      • Anchorage, Alaska, Forenede Stater, 99508
        • Anchorage Oncology Centre
      • Anchorage, Alaska, Forenede Stater, 99508
        • Katmai Oncology Group
      • Anchorage, Alaska, Forenede Stater, 99508
        • Providence Alaska Medical Center
      • Anchorage, Alaska, Forenede Stater, 99508
        • Alaska Regional Hospital
      • Fairbanks, Alaska, Forenede Stater, 99701
        • Fairbanks Memorial Hospital
    • Arizona
      • Tucson, Arizona, Forenede Stater, 85719
        • University of Arizona Cancer Center-North Campus
      • Tucson, Arizona, Forenede Stater, 85724
        • The University of Arizona Medical Center-University Campus
    • Arkansas
      • Hot Springs, Arkansas, Forenede Stater, 71913
        • CHI Saint Vincent Cancer Center Hot Springs
      • Jonesboro, Arkansas, Forenede Stater, 72401
        • Fowler Family Center for Cancer Care
      • Little Rock, Arkansas, Forenede Stater, 72205
        • University of Arkansas for Medical Sciences
    • California
      • Anaheim, California, Forenede Stater, 92806
        • Kaiser Permanente-Anaheim
      • Antioch, California, Forenede Stater, 94531
        • Kaiser Permanente-Deer Valley Medical Center
      • Arroyo Grande, California, Forenede Stater, 93420
        • PCR Oncology
      • Auburn, California, Forenede Stater, 95602
        • Sutter Auburn Faith Hospital
      • Bakersfield, California, Forenede Stater, 93301
        • AIS Cancer Center at San Joaquin Community Hospital
      • Baldwin Park, California, Forenede Stater, 91706
        • Kaiser Permanente-Baldwin Park
      • Bellflower, California, Forenede Stater, 90706
        • Kaiser Permanente-Bellflower
      • Berkeley, California, Forenede Stater, 94704
        • Alta Bates Summit Medical Center-Herrick Campus
      • Burlingame, California, Forenede Stater, 94010
        • Mills-Peninsula Medical Center
      • Corona, California, Forenede Stater, 92879
        • City of Hope Corona
      • Duarte, California, Forenede Stater, 91010
        • City of Hope Comprehensive Cancer Center
      • Fontana, California, Forenede Stater, 92335
        • Kaiser Permanente-Fontana
      • Fremont, California, Forenede Stater, 94538
        • Kaiser Permanente-Fremont
      • Fremont, California, Forenede Stater, 94538
        • Washington Hospital
      • Fremont, California, Forenede Stater, 94538
        • Palo Alto Medical Foundation-Fremont
      • Fresno, California, Forenede Stater, 93720
        • Kaiser Permanente-Fresno
      • Fullerton, California, Forenede Stater, 92835
        • Saint Jude Medical Center
      • Harbor City, California, Forenede Stater, 90710
        • Kaiser Permanente - Harbor City
      • Irvine, California, Forenede Stater, 92618
        • Kaiser Permanente-Irvine
      • La Jolla, California, Forenede Stater, 92093
        • UC San Diego Moores Cancer Center
      • Lancaster, California, Forenede Stater, 93534
        • City of Hope Antelope Valley
      • Loma Linda, California, Forenede Stater, 92354
        • Loma Linda University Medical Center
      • Los Angeles, California, Forenede Stater, 90033
        • USC / Norris Comprehensive Cancer Center
      • Los Angeles, California, Forenede Stater, 90033
        • Los Angeles County-USC Medical Center
      • Los Angeles, California, Forenede Stater, 90027
        • Kaiser Permanente Los Angeles Medical Center
      • Los Angeles, California, Forenede Stater, 90034
        • Kaiser Permanente-Cadillac
      • Marysville, California, Forenede Stater, 95901
        • Fremont - Rideout Cancer Center
      • Mission Hills, California, Forenede Stater, 91345
        • City of Hope Mission Hills
      • Modesto, California, Forenede Stater, 95355
        • Memorial Medical Center
      • Modesto, California, Forenede Stater, 95356
        • Kaiser Permanente-Modesto
      • Monterey, California, Forenede Stater, 93940
        • Community Hospital of Monterey Peninsula
      • Monterey, California, Forenede Stater, 93940
        • Pacific Cancer Care-Monterey
      • Mountain View, California, Forenede Stater, 94040
        • Palo Alto Medical Foundation-Camino Division
      • Mountain View, California, Forenede Stater, 94040
        • Palo Alto Medical Foundation-Gynecologic Oncology
      • Novato, California, Forenede Stater, 94945
        • Sutter Cancer Research Consortium
      • Oakland, California, Forenede Stater, 94611
        • Kaiser Permanente-Oakland
      • Orange, California, Forenede Stater, 92868
        • Saint Joseph Hospital - Orange
      • Palo Alto, California, Forenede Stater, 94304
        • Stanford Cancer Institute Palo Alto
      • Palo Alto, California, Forenede Stater, 94301
        • Palo Alto Medical Foundation Health Care
      • Panorama City, California, Forenede Stater, 91402
        • Kaiser Permanente - Panorama City
      • Paradise, California, Forenede Stater, 95969
        • Feather River Cancer Center
      • Rancho Cucamonga, California, Forenede Stater, 91730
        • City of Hope Rancho Cucamonga
      • Rancho Mirage, California, Forenede Stater, 92270
        • Eisenhower Medical Center
      • Redwood City, California, Forenede Stater, 94063
        • Kaiser Permanente-Redwood City
      • Richmond, California, Forenede Stater, 94801
        • Kaiser Permanente-Richmond
      • Riverside, California, Forenede Stater, 92505
        • Kaiser Permanente-Riverside
      • Roseville, California, Forenede Stater, 95661
        • Kaiser Permanente-Roseville
      • Roseville, California, Forenede Stater, 95661
        • Sutter Roseville Medical Center
      • Sacramento, California, Forenede Stater, 95816
        • Sutter Medical Center Sacramento
      • Sacramento, California, Forenede Stater, 95817
        • University of California Davis Comprehensive Cancer Center
      • Sacramento, California, Forenede Stater, 95823
        • Kaiser Permanente-South Sacramento
      • Sacramento, California, Forenede Stater, 95825
        • Kaiser Permanente - Sacramento
      • Saint Helena, California, Forenede Stater, 94574
        • Saint Helena Hospital
      • San Diego, California, Forenede Stater, 92120
        • Kaiser Permanente-San Diego Zion
      • San Diego, California, Forenede Stater, 92108
        • Kaiser Permanente-San Diego Mission
      • San Francisco, California, Forenede Stater, 94115
        • Kaiser Permanente-San Francisco
      • San Francisco, California, Forenede Stater, 94115
        • California Pacific Medical Center-Pacific Campus
      • San Jose, California, Forenede Stater, 95119
        • Kaiser Permanente-Santa Teresa-San Jose
      • San Leandro, California, Forenede Stater, 94577
        • Kaiser Permanente San Leandro
      • San Marcos, California, Forenede Stater, 92078
        • Kaiser Permanente-San Marcos
      • San Rafael, California, Forenede Stater, 94903
        • Kaiser San Rafael-Gallinas
      • San Rafael, California, Forenede Stater, 94903
        • Kaiser Permanente-San Rafael
      • Santa Clara, California, Forenede Stater, 95051
        • Kaiser Permanente Medical Center - Santa Clara
      • Santa Cruz, California, Forenede Stater, 95065
        • Palo Alto Medical Foundation-Santa Cruz
      • Santa Rosa, California, Forenede Stater, 95403
        • Kaiser Permanente-Santa Rosa
      • South San Francisco, California, Forenede Stater, 94080
        • Kaiser Permanente-South San Francisco
      • Stockton, California, Forenede Stater, 95210
        • Kaiser Permanente-Stockton
      • Sunnyvale, California, Forenede Stater, 94086
        • Palo Alto Medical Foundation-Sunnyvale
      • Truckee, California, Forenede Stater, 96161
        • Gene Upshaw Memorial Tahoe Forest Cancer Center
      • Vacaville, California, Forenede Stater, 95688
        • Kaiser Permanente Medical Center-Vacaville
      • Vacaville, California, Forenede Stater, 95687
        • Northbay Cancer Center
      • Vallejo, California, Forenede Stater, 94589
        • Kaiser Permanente-Vallejo
      • Vallejo, California, Forenede Stater, 94589
        • Sutter Solano Medical Center/Cancer Center
      • Walnut Creek, California, Forenede Stater, 94596
        • Kaiser Permanente-Walnut Creek
      • Whittier, California, Forenede Stater, 90602
        • Presbyterian Intercommunity Hospital
      • Woodland Hills, California, Forenede Stater, 91367
        • Kaiser Permanente-Woodland Hills
    • Colorado
      • Aurora, Colorado, Forenede Stater, 80045
        • University of Colorado Hospital
      • Boulder, Colorado, Forenede Stater, 80304
        • Rocky Mountain Cancer Centers-Boulder
      • Colorado Springs, Colorado, Forenede Stater, 80907
        • Penrose-Saint Francis Healthcare
      • Colorado Springs, Colorado, Forenede Stater, 80909
        • UCHealth Memorial Hospital Central
      • Colorado Springs, Colorado, Forenede Stater, 80907
        • Rocky Mountain Cancer Centers-Penrose
      • Denver, Colorado, Forenede Stater, 80205
        • Kaiser Permanente-Franklin
      • Denver, Colorado, Forenede Stater, 80218
        • SCL Health Saint Joseph Hospital
      • Denver, Colorado, Forenede Stater, 80222
        • Colorado Cancer Research Program NCORP
      • Englewood, Colorado, Forenede Stater, 80113
        • Comprehensive Cancer Care and Research Institute of Colorado LLC
      • Fort Collins, Colorado, Forenede Stater, 80524
        • Poudre Valley Hospital
      • Greeley, Colorado, Forenede Stater, 80631
        • North Colorado Medical Center
      • Lafayette, Colorado, Forenede Stater, 80026
        • Kaiser Permanente-Rock Creek
      • Lone Tree, Colorado, Forenede Stater, 80124
        • Kaiser Permanente-Lone Tree
      • Lone Tree, Colorado, Forenede Stater, 80124
        • Sky Ridge Medical Center
      • Lone Tree, Colorado, Forenede Stater, 80124
        • Rocky Mountain Cancer Centers-Sky Ridge
      • Longmont, Colorado, Forenede Stater, 80501
        • Longmont United Hospital
      • Longmont, Colorado, Forenede Stater, 80501
        • Rocky Mountain Cancer Centers-Longmont
      • Loveland, Colorado, Forenede Stater, 80539
        • McKee Medical Center
      • Parker, Colorado, Forenede Stater, 80138
        • Parker Adventist Hospital
      • Parker, Colorado, Forenede Stater, 80138
        • Rocky Mountain Cancer Centers-Parker
    • Connecticut
      • Danbury, Connecticut, Forenede Stater, 06810
        • Danbury Hospital
      • Derby, Connecticut, Forenede Stater, 06418
        • Smilow Cancer Hospital-Derby Care Center
      • Guilford, Connecticut, Forenede Stater, 06437
        • Yale-New Haven Shoreline Medical Center
      • Hartford, Connecticut, Forenede Stater, 06105
        • Smilow Cancer Hospital Care Center at Saint Francis
      • Hartford, Connecticut, Forenede Stater, 06102
        • Hartford Hospital
      • Meriden, Connecticut, Forenede Stater, 06451
        • Midstate Medical Center
      • New Britain, Connecticut, Forenede Stater, 06050
        • The Hospital of Central Connecticut
      • New Haven, Connecticut, Forenede Stater, 06520
        • Yale University
      • New Haven, Connecticut, Forenede Stater, 06510
        • Smilow Cancer Center/Yale-New Haven Hospital
      • North Haven, Connecticut, Forenede Stater, 06473
        • Yale-New Haven Hospital North Haven Medical Center
      • Norwich, Connecticut, Forenede Stater, 06360
        • Eastern Connecticut Hematology and Oncology Associates
      • Orange, Connecticut, Forenede Stater, 06477
        • Smilow Cancer Hospital-Orange Care Center
      • Torrington, Connecticut, Forenede Stater, 06790
        • Smilow Cancer Hospital-Torrington Care Center
      • Waterbury, Connecticut, Forenede Stater, 06708
        • Smilow Cancer Hospital-Waterbury Care Center
      • Waterford, Connecticut, Forenede Stater, 06385
        • Lawrence and Memorial Cancer Center
      • West Haven, Connecticut, Forenede Stater, 06516
        • Veterans Affairs Connecticut Healthcare System-West Haven Campus
    • Delaware
      • Lewes, Delaware, Forenede Stater, 19958
        • Beebe Medical Center
      • Newark, Delaware, Forenede Stater, 19713
        • Helen F Graham Cancer Center
      • Newark, Delaware, Forenede Stater, 19713
        • Delaware Clinical and Laboratory Physicians PA
      • Newark, Delaware, Forenede Stater, 19713
        • Medical Oncology Hematology Consultants PA
      • Newark, Delaware, Forenede Stater, 19718
        • Christiana Care Health System-Christiana Hospital
      • Newark, Delaware, Forenede Stater, 19713
        • Regional Hematology and Oncology PA
      • Rehoboth Beach, Delaware, Forenede Stater, 19971
        • Beebe Health Campus
      • Seaford, Delaware, Forenede Stater, 19973
        • Nanticoke Memorial Hospital
      • Wilmington, Delaware, Forenede Stater, 19801
        • Christiana Care Health System-Wilmington Hospital
    • District of Columbia
      • Washington, District of Columbia, Forenede Stater, 20007
        • MedStar Georgetown University Hospital
      • Washington, District of Columbia, Forenede Stater, 20016
        • Sibley Memorial Hospital
      • Washington, District of Columbia, Forenede Stater, 20002
        • Kaiser Permanente-Capitol Hill Medical Center
    • Florida
      • Aventura, Florida, Forenede Stater, 33180
        • Mount Sinai Comprehensive Cancer Center at Aventura
      • Deerfield Beach, Florida, Forenede Stater, 33442
        • UM Sylvester Comprehensive Cancer Center at Deerfield Beach
      • Gainesville, Florida, Forenede Stater, 32610
        • University of Florida Health Science Center - Gainesville
      • Hollywood, Florida, Forenede Stater, 33021
        • Memorial Regional Hospital/Joe DiMaggio Children's Hospital
      • Hollywood, Florida, Forenede Stater, 33021
        • UM Sylvester Comprehensive Cancer Center at Hollywood
      • Miami, Florida, Forenede Stater, 33136
        • University of Miami Miller School of Medicine-Sylvester Cancer Center
      • Miami Beach, Florida, Forenede Stater, 33140
        • Mount Sinai Medical Center
      • Pembroke Pines, Florida, Forenede Stater, 33028
        • Memorial Hospital West
      • Pensacola, Florida, Forenede Stater, 32504
        • Sacred Heart Hospital
      • Plantation, Florida, Forenede Stater, 33324
        • UM Sylvester Comprehensive Cancer Center at Plantation
      • Tampa, Florida, Forenede Stater, 33612
        • Moffitt Cancer Center
    • Georgia
      • Albany, Georgia, Forenede Stater, 31701
        • Phoebe Putney Memorial Hospital
      • Atlanta, Georgia, Forenede Stater, 30308
        • Emory University Hospital Midtown
      • Atlanta, Georgia, Forenede Stater, 30322
        • Emory University Hospital/Winship Cancer Institute
      • Atlanta, Georgia, Forenede Stater, 30342
        • Emory Saint Joseph's Hospital
      • Atlanta, Georgia, Forenede Stater, 30309
        • Piedmont Hospital
      • Atlanta, Georgia, Forenede Stater, 30342
        • Northside Hospital
      • Augusta, Georgia, Forenede Stater, 30912
        • Augusta University Medical Center
      • Columbus, Georgia, Forenede Stater, 31904
        • John B Amos Cancer Center
      • Cumming, Georgia, Forenede Stater, 30041
        • Northside Hospital-Forsyth
      • Decatur, Georgia, Forenede Stater, 30033
        • Dekalb Medical Center
      • Gainesville, Georgia, Forenede Stater, 30501
        • Northeast Georgia Medical Center-Gainesville
      • Lawrenceville, Georgia, Forenede Stater, 30046
        • Gwinnett Medical Center
      • Macon, Georgia, Forenede Stater, 31201
        • Medical Center of Central Georgia
      • Rome, Georgia, Forenede Stater, 30165
        • Harbin Clinic Medical Oncology and Clinical Research
      • Savannah, Georgia, Forenede Stater, 31405
        • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
      • Savannah, Georgia, Forenede Stater, 31404
        • Memorial Health University Medical Center
      • Valdosta, Georgia, Forenede Stater, 31602
        • South Georgia Medical Center/Pearlman Cancer Center
    • Hawaii
      • 'Aiea, Hawaii, Forenede Stater, 96701
        • Pali Momi Medical Center
      • 'Aiea, Hawaii, Forenede Stater, 96701
        • The Cancer Center of Hawaii-Pali Momi
      • 'Aiea, Hawaii, Forenede Stater, 96701
        • Hawaii Oncology Inc-Pali Momi
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Queen's Medical Center
      • Honolulu, Hawaii, Forenede Stater, 96817
        • The Cancer Center of Hawaii-Liliha
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Straub Clinic and Hospital
      • Honolulu, Hawaii, Forenede Stater, 96813
        • University of Hawaii Cancer Center
      • Honolulu, Hawaii, Forenede Stater, 96817
        • Hawaii Cancer Care Inc-Liliha
      • Honolulu, Hawaii, Forenede Stater, 96817
        • Kuakini Medical Center
      • Honolulu, Hawaii, Forenede Stater, 96826
        • Kapiolani Medical Center for Women and Children
      • Honolulu, Hawaii, Forenede Stater, 96819
        • Kaiser Permanente Moanalua Medical Center
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Hawaii Cancer Care Inc-POB II
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Hawaii Oncology Inc-POB I
      • Honolulu, Hawaii, Forenede Stater, 96817
        • Hawaii Oncology Inc-Kuakini
    • Idaho
      • Boise, Idaho, Forenede Stater, 83706
        • Saint Alphonsus Cancer Care Center-Boise
      • Boise, Idaho, Forenede Stater, 83712
        • Saint Luke's Mountain States Tumor Institute
      • Coeur d'Alene, Idaho, Forenede Stater, 83814
        • Kootenai Medical Center
      • Fruitland, Idaho, Forenede Stater, 83619
        • Saint Luke's Mountain States Tumor Institute - Fruitland
      • Meridian, Idaho, Forenede Stater, 83642
        • Saint Luke's Mountain States Tumor Institute - Meridian
      • Nampa, Idaho, Forenede Stater, 83686
        • Saint Luke's Mountain States Tumor Institute - Nampa
      • Post Falls, Idaho, Forenede Stater, 83854
        • Kootenai Cancer Center
      • Sandpoint, Idaho, Forenede Stater, 83864
        • Kootenai Cancer Clinic
      • Twin Falls, Idaho, Forenede Stater, 83301
        • Saint Luke's Mountain States Tumor Institute-Twin Falls
    • Illinois
      • Aurora, Illinois, Forenede Stater, 60504
        • Rush - Copley Medical Center
      • Bloomington, Illinois, Forenede Stater, 61704
        • Illinois CancerCare-Bloomington
      • Bloomington, Illinois, Forenede Stater, 61701
        • Saint Joseph Medical Center
      • Canton, Illinois, Forenede Stater, 61520
        • Illinois CancerCare-Canton
      • Carthage, Illinois, Forenede Stater, 62321
        • Illinois CancerCare-Carthage
      • Centralia, Illinois, Forenede Stater, 62801
        • Centralia Oncology Clinic
      • Chicago, Illinois, Forenede Stater, 60611
        • Northwestern University
      • Chicago, Illinois, Forenede Stater, 60612
        • Rush University Medical Center
      • Chicago, Illinois, Forenede Stater, 60637
        • University of Chicago Comprehensive Cancer Center
      • Chicago, Illinois, Forenede Stater, 60612
        • John H Stroger Jr Hospital of Cook County
      • Chicago, Illinois, Forenede Stater, 60608
        • Mount Sinai Hospital Medical Center
      • Chicago, Illinois, Forenede Stater, 60625
        • Swedish Covenant Hospital
      • Danville, Illinois, Forenede Stater, 61832
        • Carle on Vermilion
      • Decatur, Illinois, Forenede Stater, 62526
        • Decatur Memorial Hospital
      • Decatur, Illinois, Forenede Stater, 62526
        • Cancer Care Specialists of Illinois - Decatur
      • Effingham, Illinois, Forenede Stater, 62401
        • Crossroads Cancer Center
      • Effingham, Illinois, Forenede Stater, 62401
        • Carle Physician Group-Effingham
      • Elgin, Illinois, Forenede Stater, 60123
        • Advocate Sherman Hospital
      • Elk Grove Village, Illinois, Forenede Stater, 60007
        • AMITA Health Alexian Brothers Medical Center
      • Eureka, Illinois, Forenede Stater, 61530
        • Illinois CancerCare-Eureka
      • Evanston, Illinois, Forenede Stater, 60201
        • NorthShore University HealthSystem-Evanston Hospital
      • Evanston, Illinois, Forenede Stater, 60202
        • Saint Francis Hospital
      • Galesburg, Illinois, Forenede Stater, 61401
        • Western Illinois Cancer Treatment Center
      • Galesburg, Illinois, Forenede Stater, 61401
        • Illinois CancerCare-Galesburg
      • Geneva, Illinois, Forenede Stater, 60134
        • Northwestern Medicine Cancer Center Delnor
      • Glenview, Illinois, Forenede Stater, 60026
        • NorthShore University HealthSystem-Glenbrook Hospital
      • Harvey, Illinois, Forenede Stater, 60426
        • Ingalls Memorial Hospital
      • Highland Park, Illinois, Forenede Stater, 60035
        • NorthShore University HealthSystem-Highland Park Hospital
      • Hines, Illinois, Forenede Stater, 60141
        • Hines Veterans Administration Hospital
      • Hinsdale, Illinois, Forenede Stater, 60521
        • AMITA Health Cancer Institute and Outpatient Center
      • Joliet, Illinois, Forenede Stater, 60435
        • Joliet Oncology-Hematology Associates Limited
      • Kankakee, Illinois, Forenede Stater, 60901
        • Presence Saint Mary's Hospital
      • Kewanee, Illinois, Forenede Stater, 61443
        • Illinois CancerCare-Kewanee Clinic
      • Libertyville, Illinois, Forenede Stater, 60048
        • NorthShore Hematology Oncology-Libertyville
      • Macomb, Illinois, Forenede Stater, 61455
        • Illinois CancerCare-Macomb
      • Mattoon, Illinois, Forenede Stater, 61938
        • Carle Physician Group-Mattoon/Charleston
      • Maywood, Illinois, Forenede Stater, 60153
        • Loyola University Medical Center
      • Moline, Illinois, Forenede Stater, 61265
        • Trinity Medical Center
      • Mount Vernon, Illinois, Forenede Stater, 62864
        • Good Samaritan Regional Health Center
      • Naperville, Illinois, Forenede Stater, 60540
        • AMG Oncology - Naperville
      • New Lenox, Illinois, Forenede Stater, 60451
        • UC Comprehensive Cancer Center at Silver Cross
      • Niles, Illinois, Forenede Stater, 60714
        • Illinois Cancer Specialists-Niles
      • Orland Park, Illinois, Forenede Stater, 60462
        • University of Chicago Medicine-Orland Park
      • Ottawa, Illinois, Forenede Stater, 61350
        • Illinois CancerCare-Ottawa Clinic
      • Ottawa, Illinois, Forenede Stater, 61350
        • Radiation Oncology of Northern Illinois
      • Pekin, Illinois, Forenede Stater, 61554
        • Illinois CancerCare-Pekin
      • Pekin, Illinois, Forenede Stater, 61554
        • OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
      • Peoria, Illinois, Forenede Stater, 61636
        • Methodist Medical Center of Illinois
      • Peoria, Illinois, Forenede Stater, 61637
        • OSF Saint Francis Medical Center
      • Peoria, Illinois, Forenede Stater, 61615
        • Illinois CancerCare-Peoria
      • Peoria, Illinois, Forenede Stater, 61615
        • OSF Saint Francis Radiation Oncology at Peoria Cancer Center
      • Peru, Illinois, Forenede Stater, 61354
        • Illinois CancerCare-Peru
      • Peru, Illinois, Forenede Stater, 61354
        • Valley Radiation Oncology
      • Princeton, Illinois, Forenede Stater, 61356
        • Illinois CancerCare-Princeton
      • Skokie, Illinois, Forenede Stater, 60076
        • Hematology Oncology Associates of Illinois - Skokie
      • Springfield, Illinois, Forenede Stater, 62781
        • Memorial Medical Center
      • Springfield, Illinois, Forenede Stater, 62702
        • Southern Illinois University School of Medicine
      • Springfield, Illinois, Forenede Stater, 62702
        • Springfield Clinic
      • Springfield, Illinois, Forenede Stater, 62702
        • Central Illinois Hematology Oncology Center
      • Swansea, Illinois, Forenede Stater, 62226
        • Cancer Care Specialists of Illinois-Swansea
      • Urbana, Illinois, Forenede Stater, 61801
        • Carle Cancer Center
      • Urbana, Illinois, Forenede Stater, 61801
        • The Carle Foundation Hospital
      • Warrenville, Illinois, Forenede Stater, 60555
        • Northwestern Medicine Cancer Center Warrenville
      • Yorkville, Illinois, Forenede Stater, 60560
        • Rush-Copley Healthcare Center
    • Indiana
      • Carmel, Indiana, Forenede Stater, 46032
        • IU Health North Hospital
      • Elkhart, Indiana, Forenede Stater, 46514
        • Michiana Hematology Oncology PC-Elkhart
      • Fort Wayne, Indiana, Forenede Stater, 46805
        • Parkview Hospital Randallia
      • Indianapolis, Indiana, Forenede Stater, 46237
        • Franciscan Health Indianapolis
      • Indianapolis, Indiana, Forenede Stater, 46202
        • Indiana University/Melvin and Bren Simon Cancer Center
      • Indianapolis, Indiana, Forenede Stater, 46202
        • Sidney and Lois Eskenazi Hospital
      • Indianapolis, Indiana, Forenede Stater, 46202
        • Richard L. Roudebush Veterans Affairs Medical Center
      • Indianapolis, Indiana, Forenede Stater, 46219
        • IU Health Central Indiana Cancer Centers-East
      • Indianapolis, Indiana, Forenede Stater, 46290
        • Springmill Medical Center
      • Indianapolis, Indiana, Forenede Stater, 46202
        • IU Health Methodist Hospital
      • Lafayette, Indiana, Forenede Stater, 47904
        • IU Health Arnett Cancer Care
      • Mishawaka, Indiana, Forenede Stater, 46545
        • Memorial Regional Cancer Center Day Road
      • Mishawaka, Indiana, Forenede Stater, 46545
        • Michiana Hematology Oncology PC-Mishawaka
      • Mooresville, Indiana, Forenede Stater, 46158
        • Franciscan Health Mooresville
      • Munster, Indiana, Forenede Stater, 46321
        • The Community Hospital
      • Plymouth, Indiana, Forenede Stater, 46563
        • Michiana Hematology Oncology PC-Plymouth
      • Richmond, Indiana, Forenede Stater, 47374
        • Reid Health
      • South Bend, Indiana, Forenede Stater, 46601
        • Memorial Hospital of South Bend
      • South Bend, Indiana, Forenede Stater, 46601
        • Michiana Hematology Oncology PC-South Bend
      • South Bend, Indiana, Forenede Stater, 46628
        • Northern Indiana Cancer Research Consortium
      • Terre Haute, Indiana, Forenede Stater, 47804
        • Union Hospital
      • Westville, Indiana, Forenede Stater, 46391
        • Michiana Hematology Oncology PC-Westville
    • Iowa
      • Ames, Iowa, Forenede Stater, 50010
        • McFarland Clinic PC - Ames
      • Ames, Iowa, Forenede Stater, 50010
        • Mary Greeley Medical Center
      • Bettendorf, Iowa, Forenede Stater, 52722
        • University of Iowa Healthcare Cancer Services Quad Cities
      • Boone, Iowa, Forenede Stater, 50036
        • McFarland Clinic PC-Boone
      • Clive, Iowa, Forenede Stater, 50325
        • Mercy Cancer Center-West Lakes
      • Clive, Iowa, Forenede Stater, 50325
        • Medical Oncology and Hematology Associates-West Des Moines
      • Council Bluffs, Iowa, Forenede Stater, 51503
        • Alegent Health Mercy Hospital
      • Creston, Iowa, Forenede Stater, 50801
        • Greater Regional Medical Center
      • Davenport, Iowa, Forenede Stater, 52803
        • Genesis Medical Center - East Campus
      • Des Moines, Iowa, Forenede Stater, 50309
        • Iowa Methodist Medical Center
      • Des Moines, Iowa, Forenede Stater, 50314
        • Mercy Medical Center - Des Moines
      • Des Moines, Iowa, Forenede Stater, 50309
        • Medical Oncology and Hematology Associates-Des Moines
      • Des Moines, Iowa, Forenede Stater, 50314
        • Broadlawns Medical Center
      • Des Moines, Iowa, Forenede Stater, 50316
        • Iowa Lutheran Hospital
      • Des Moines, Iowa, Forenede Stater, 50309
        • Iowa-Wide Oncology Research Coalition NCORP
      • Des Moines, Iowa, Forenede Stater, 50314
        • Medical Oncology and Hematology Associates-Laurel
      • Fort Dodge, Iowa, Forenede Stater, 50501
        • McFarland Clinic PC-Trinity Cancer Center
      • Fort Dodge, Iowa, Forenede Stater, 50501
        • Trinity Regional Medical Center
      • Iowa City, Iowa, Forenede Stater, 52242
        • University of Iowa/Holden Comprehensive Cancer Center
      • Jefferson, Iowa, Forenede Stater, 50129
        • McFarland Clinic PC-Jefferson
      • Marshalltown, Iowa, Forenede Stater, 50158
        • McFarland Clinic PC-Marshalltown
      • Mason City, Iowa, Forenede Stater, 50401
        • Mercy Medical Center - North Iowa
      • Sioux City, Iowa, Forenede Stater, 51101
        • Siouxland Regional Cancer Center
      • Waterloo, Iowa, Forenede Stater, 50702
        • Covenant Medical Center
      • West Des Moines, Iowa, Forenede Stater, 50266-7700
        • Methodist West Hospital
      • West Des Moines, Iowa, Forenede Stater, 50266
        • Mercy Medical Center-West Lakes
    • Kansas
      • Chanute, Kansas, Forenede Stater, 66720
        • Cancer Center of Kansas - Chanute
      • Dodge City, Kansas, Forenede Stater, 67801
        • Cancer Center of Kansas - Dodge City
      • El Dorado, Kansas, Forenede Stater, 67042
        • Cancer Center of Kansas - El Dorado
      • Emporia, Kansas, Forenede Stater, 66801
        • Newman Regional Health
      • Fort Scott, Kansas, Forenede Stater, 66701
        • Cancer Center of Kansas - Fort Scott
      • Garden City, Kansas, Forenede Stater, 67846
        • Central Care Cancer Center - Garden City
      • Garden City, Kansas, Forenede Stater, 67846
        • Saint Catherine Hospital
      • Great Bend, Kansas, Forenede Stater, 67530
        • Central Care Cancer Center - Great Bend
      • Great Bend, Kansas, Forenede Stater, 67530
        • Saint Rose Ambulatory and Surgery Center
      • Hays, Kansas, Forenede Stater, 67601
        • Hays Medical Center
      • Independence, Kansas, Forenede Stater, 67301
        • Cancer Center of Kansas-Independence
      • Kansas City, Kansas, Forenede Stater, 66160
        • University of Kansas Cancer Center
      • Kansas City, Kansas, Forenede Stater, 66112
        • University of Kansas Cancer Center-West
      • Kingman, Kansas, Forenede Stater, 67068
        • Cancer Center of Kansas-Kingman
      • Lawrence, Kansas, Forenede Stater, 66044
        • Lawrence Memorial Hospital
      • Lenexa, Kansas, Forenede Stater, 66219
        • Kansas Institute of Medicine Cancer and Blood Center
      • Lenexa, Kansas, Forenede Stater, 66219
        • Minimally Invasive Surgery Hospital
      • Liberal, Kansas, Forenede Stater, 67905
        • Cancer Center of Kansas-Liberal
      • Manhattan, Kansas, Forenede Stater, 66502
        • Cancer Center of Kansas-Manhattan
      • McPherson, Kansas, Forenede Stater, 67460
        • Cancer Center of Kansas - McPherson
      • Newton, Kansas, Forenede Stater, 67114
        • Cancer Center of Kansas - Newton
      • Olathe, Kansas, Forenede Stater, 66061
        • Olathe Medical Center
      • Overland Park, Kansas, Forenede Stater, 66210
        • University of Kansas Cancer Center-Overland Park
      • Overland Park, Kansas, Forenede Stater, 66209
        • Menorah Medical Center
      • Overland Park, Kansas, Forenede Stater, 66213
        • Saint Luke's South Hospital
      • Parsons, Kansas, Forenede Stater, 67357
        • Cancer Center of Kansas - Parsons
      • Pittsburg, Kansas, Forenede Stater, 66762
        • Via Christi Hospital-Pittsburg
      • Prairie Village, Kansas, Forenede Stater, 66208
        • Kansas City NCI Community Oncology Research Program
      • Pratt, Kansas, Forenede Stater, 67124
        • Cancer Center of Kansas - Pratt
      • Salina, Kansas, Forenede Stater, 67401
        • Salina Regional Health Center
      • Salina, Kansas, Forenede Stater, 67401
        • Cancer Center of Kansas - Salina
      • Topeka, Kansas, Forenede Stater, 66606
        • Cotton O'Neil Cancer Center / Stormont Vail Health
      • Topeka, Kansas, Forenede Stater, 66606
        • Saint Francis Hospital and Medical Center - Topeka
      • Wellington, Kansas, Forenede Stater, 67152
        • Cancer Center of Kansas - Wellington
      • Westwood, Kansas, Forenede Stater, 66205
        • University of Kansas Hospital-Westwood Cancer Center
      • Wichita, Kansas, Forenede Stater, 67208
        • Cancer Center of Kansas-Wichita Medical Arts Tower
      • Wichita, Kansas, Forenede Stater, 67214
        • Cancer Center of Kansas - Wichita
      • Wichita, Kansas, Forenede Stater, 67214
        • Wichita NCI Community Oncology Research Program
      • Wichita, Kansas, Forenede Stater, 67214
        • Via Christi Regional Medical Center
      • Winfield, Kansas, Forenede Stater, 67156
        • Cancer Center of Kansas - Winfield
    • Kentucky
      • Ashland, Kentucky, Forenede Stater, 41101
        • King's Daughter's Medical Center
      • Bardstown, Kentucky, Forenede Stater, 40004
        • Flaget Memorial Hospital
      • Corbin, Kentucky, Forenede Stater, 40701
        • Baptist Health Corbin
      • Crestview Hills, Kentucky, Forenede Stater, 41017
        • Oncology Hematology Care Inc-Crestview
      • Elizabethtown, Kentucky, Forenede Stater, 42701
        • Hardin Memorial Hospital
      • Lexington, Kentucky, Forenede Stater, 40536
        • University of Kentucky/Markey Cancer Center
      • Lexington, Kentucky, Forenede Stater, 40504
        • Saint Joseph Radiation Oncology Resource Center
      • Lexington, Kentucky, Forenede Stater, 40509
        • Saint Joseph Hospital East
      • Lexington, Kentucky, Forenede Stater, 40503
        • Baptist Health Lexington
      • Louisville, Kentucky, Forenede Stater, 40202
        • Norton Hospital Pavilion and Medical Campus
      • Louisville, Kentucky, Forenede Stater, 40202
        • The James Graham Brown Cancer Center at University of Louisville
      • Louisville, Kentucky, Forenede Stater, 40202
        • Jewish Hospital
      • Louisville, Kentucky, Forenede Stater, 40207
        • Norton Suburban Hospital and Medical Campus
      • Louisville, Kentucky, Forenede Stater, 40207
        • Baptist Health Louisville
      • Louisville, Kentucky, Forenede Stater, 40215
        • Saints Mary and Elizabeth Hospital
      • Louisville, Kentucky, Forenede Stater, 40245
        • Jewish Hospital Medical Center Northeast
      • Madisonville, Kentucky, Forenede Stater, 42431
        • Baptist Health Madisonville/Merle Mahr Cancer Center
      • Paducah, Kentucky, Forenede Stater, 42003
        • Baptist Health Paducah
    • Louisiana
      • Baton Rouge, Louisiana, Forenede Stater, 70805
        • LSU Health Baton Rouge-North Clinic
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Louisiana Hematology Oncology Associates LLC
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Mary Bird Perkins Cancer Center
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Our Lady of the Lake Physicians Group - Medical Oncology
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Ochsner Health Center-Summa
      • Baton Rouge, Louisiana, Forenede Stater, 70816
        • Medical Center of Baton Rouge
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Hematology/Oncology Clinic LLP
      • Covington, Louisiana, Forenede Stater, 70433
        • Mary Bird Cancer Center/Saint Tammany Parish
      • Covington, Louisiana, Forenede Stater, 70433
        • Northshore Oncology Associates-Covington
      • Houma, Louisiana, Forenede Stater, 70360
        • Mary Bird Perkins Cancer Center/Terrebonne General Medical Center
      • Houma, Louisiana, Forenede Stater, 70360
        • Oncology Center of The South Incorporated
      • Kenner, Louisiana, Forenede Stater, 70065
        • Ochsner Medical Center Kenner
      • Metairie, Louisiana, Forenede Stater, 70006
        • East Jefferson General Hospital
      • Metairie, Louisiana, Forenede Stater, 70006
        • Robert Veith MD LLC
      • Monroe, Louisiana, Forenede Stater, 71202
        • University Health-Conway
      • New Orleans, Louisiana, Forenede Stater, 70121
        • Ochsner Medical Center Jefferson
      • New Orleans, Louisiana, Forenede Stater, 70112
        • Tulane University Health Sciences Center
      • New Orleans, Louisiana, Forenede Stater, 70112
        • University Medical Center New Orleans
      • New Orleans, Louisiana, Forenede Stater, 70112
        • Louisiana State University Health Science Center
      • New Orleans, Louisiana, Forenede Stater, 70115
        • LSU Healthcare Network/Saint Charles
      • Shreveport, Louisiana, Forenede Stater, 71103
        • Louisiana State University Health Sciences Center Shreveport
    • Maine
      • Augusta, Maine, Forenede Stater, 04330
        • Harold Alfond Center for Cancer Care
      • Bangor, Maine, Forenede Stater, 04401
        • Eastern Maine Medical Center
      • Belfast, Maine, Forenede Stater, 04915
        • Waldo County General Hospital
      • Biddeford, Maine, Forenede Stater, 04005
        • MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford
      • Brewer, Maine, Forenede Stater, 04412
        • Lafayette Family Cancer Center-EMMC
      • Portland, Maine, Forenede Stater, 04101
        • Mercy Hospital
      • Rockport, Maine, Forenede Stater, 04856
        • Penobscot Bay Medical Center
      • Sanford, Maine, Forenede Stater, 04073
        • MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford
      • York, Maine, Forenede Stater, 03909
        • York Hospital
    • Maryland
      • Baltimore, Maryland, Forenede Stater, 21237
        • MedStar Franklin Square Medical Center/Weinberg Cancer Institute
      • Baltimore, Maryland, Forenede Stater, 21287
        • Johns Hopkins University/Sidney Kimmel Cancer Center
      • Baltimore, Maryland, Forenede Stater, 21215
        • Sinai Hospital of Baltimore
      • Baltimore, Maryland, Forenede Stater, 21204
        • Greater Baltimore Medical Center
      • Baltimore, Maryland, Forenede Stater, 21201
        • University of Maryland/Greenebaum Cancer Center
      • Baltimore, Maryland, Forenede Stater, 21218
        • MedStar Union Memorial Hospital
      • Baltimore, Maryland, Forenede Stater, 21229
        • Saint Agnes Hospital
      • Baltimore, Maryland, Forenede Stater, 21244
        • Kaiser Permanente-Woodlawn Medical Center
      • Cumberland, Maryland, Forenede Stater, 21502
        • Western Maryland Regional Medical Center
      • Frederick, Maryland, Forenede Stater, 21701
        • Frederick Memorial Hospital
      • Gaithersburg, Maryland, Forenede Stater, 20879
        • Kaiser Permanente-Gaithersburg Medical Center
      • Kensington, Maryland, Forenede Stater, 20895
        • Kaiser Permanente - Kensington Medical Center
      • Largo, Maryland, Forenede Stater, 20774
        • Kaiser Permanente - Largo Medical Center
      • Randallstown, Maryland, Forenede Stater, 21133
        • Northwest Hospital Center
      • Salisbury, Maryland, Forenede Stater, 21801
        • Peninsula Regional Medical Center
      • Westminster, Maryland, Forenede Stater, 21157
        • William E Kahlert Regional Cancer Center/Sinai Hospital
    • Massachusetts
      • Beverly, Massachusetts, Forenede Stater, 01915
        • Beverly Hospital
      • Boston, Massachusetts, Forenede Stater, 02215
        • Beth Israel Deaconess Medical Center
      • Boston, Massachusetts, Forenede Stater, 02118
        • Boston Medical Center
      • Boston, Massachusetts, Forenede Stater, 02114
        • Massachusetts General Hospital Cancer Center
      • Burlington, Massachusetts, Forenede Stater, 01805
        • Lahey Hospital and Medical Center
      • Fitchburg, Massachusetts, Forenede Stater, 01420
        • Simonds-Sinon Regional Cancer Center
      • Gloucester, Massachusetts, Forenede Stater, 01930
        • Addison Gilbert Hospital
      • Lowell, Massachusetts, Forenede Stater, 01854
        • Lowell General Hospital
      • Milford, Massachusetts, Forenede Stater, 01757
        • Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
      • South Weymouth, Massachusetts, Forenede Stater, 02190
        • Dana-Farber/Brigham and Women's Cancer Center at South Shore
      • Springfield, Massachusetts, Forenede Stater, 01199
        • Baystate Medical Center
      • Worcester, Massachusetts, Forenede Stater, 01655
        • University of Massachusetts Medical School
    • Michigan
      • Adrian, Michigan, Forenede Stater, 49221
        • Hickman Cancer Center
      • Ann Arbor, Michigan, Forenede Stater, 48109
        • University of Michigan Comprehensive Cancer Center
      • Ann Arbor, Michigan, Forenede Stater, 48106
        • Saint Joseph Mercy Hospital
      • Ann Arbor, Michigan, Forenede Stater, 48105
        • Veteran's Administration Medical Center - Ann Arbor
      • Battle Creek, Michigan, Forenede Stater, 49017
        • Bronson Battle Creek
      • Brighton, Michigan, Forenede Stater, 48114
        • Saint Joseph Mercy Brighton
      • Brighton, Michigan, Forenede Stater, 48114
        • IHA Hematology Oncology Consultants-Brighton
      • Brownstown, Michigan, Forenede Stater, 48183
        • Henry Ford Cancer Institute?Downriver
      • Canton, Michigan, Forenede Stater, 48188
        • Saint Joseph Mercy Canton
      • Canton, Michigan, Forenede Stater, 48188
        • IHA Hematology Oncology Consultants-Canton
      • Chelsea, Michigan, Forenede Stater, 48118
        • Saint Joseph Mercy Chelsea
      • Chelsea, Michigan, Forenede Stater, 48118
        • IHA Hematology Oncology Consultants-Chelsea
      • Clarkston, Michigan, Forenede Stater, 48346
        • Hematology Oncology Consultants-Clarkston
      • Clarkston, Michigan, Forenede Stater, 48346
        • Newland Medical Associates-Clarkston
      • Clinton Township, Michigan, Forenede Stater, 48038
        • Henry Ford Macomb Hospital-Clinton Township
      • Dearborn, Michigan, Forenede Stater, 48126
        • Henry Ford Medical Center-Fairlane
      • Dearborn, Michigan, Forenede Stater, 48124
        • Beaumont Hospital-Dearborn
      • Detroit, Michigan, Forenede Stater, 48202
        • Henry Ford Hospital
      • Detroit, Michigan, Forenede Stater, 48236
        • Saint John Hospital and Medical Center
      • Detroit, Michigan, Forenede Stater, 48201
        • Wayne State University/Karmanos Cancer Institute
      • Escanaba, Michigan, Forenede Stater, 49829
        • Green Bay Oncology - Escanaba
      • Farmington Hills, Michigan, Forenede Stater, 48334
        • Weisberg Cancer Treatment Center
      • Flint, Michigan, Forenede Stater, 48503
        • Hurley Medical Center
      • Flint, Michigan, Forenede Stater, 48503
        • Genesys Hurley Cancer Institute
      • Grand Rapids, Michigan, Forenede Stater, 49503
        • Spectrum Health at Butterworth Campus
      • Grand Rapids, Michigan, Forenede Stater, 49503
        • Mercy Health Saint Mary's
      • Jackson, Michigan, Forenede Stater, 49201
        • Allegiance Health
      • Kalamazoo, Michigan, Forenede Stater, 49007
        • West Michigan Cancer Center
      • Kalamazoo, Michigan, Forenede Stater, 49048
        • Borgess Medical Center
      • Lansing, Michigan, Forenede Stater, 48912
        • Sparrow Hospital
      • Livonia, Michigan, Forenede Stater, 48154
        • Saint Mary Mercy Hospital
      • Midland, Michigan, Forenede Stater, 48670
        • Mid-Michigan Medical Center - Midland
      • Monroe, Michigan, Forenede Stater, 48162
        • Monroe Cancer Center
      • Muskegon, Michigan, Forenede Stater, 49444
        • Mercy Health Mercy Campus
      • Niles, Michigan, Forenede Stater, 49120
        • Lakeland Hospital Niles
      • Novi, Michigan, Forenede Stater, 48377
        • Henry Ford Medical Center-Columbus
      • Novi, Michigan, Forenede Stater, 48374-1236
        • Assarian Cancer Center
      • Pontiac, Michigan, Forenede Stater, 48341
        • Saint Joseph Mercy Oakland
      • Pontiac, Michigan, Forenede Stater, 48341
        • Hope Cancer Center
      • Pontiac, Michigan, Forenede Stater, 48341
        • Newland Medical Associates-Pontiac
      • Port Huron, Michigan, Forenede Stater, 48060
        • Lake Huron Medical Center
      • Reed City, Michigan, Forenede Stater, 49677
        • Spectrum Health Reed City Hospital
      • Royal Oak, Michigan, Forenede Stater, 48073
        • William Beaumont Hospital-Royal Oak
      • Saginaw, Michigan, Forenede Stater, 48601
        • Saint Mary's of Michigan
      • Saint Joseph, Michigan, Forenede Stater, 49085
        • Lakeland Medical Center Saint Joseph
      • Saint Joseph, Michigan, Forenede Stater, 49085
        • Marie Yeager Cancer Center
      • Southfield, Michigan, Forenede Stater, 48075
        • Providence Hospital-Southfield Cancer Center
      • Traverse City, Michigan, Forenede Stater, 49684
        • Munson Medical Center
      • Troy, Michigan, Forenede Stater, 48098
        • William Beaumont Hospital - Troy
      • Warren, Michigan, Forenede Stater, 48093
        • Saint John Macomb-Oakland Hospital
      • West Bloomfield, Michigan, Forenede Stater, 48322
        • Henry Ford West Bloomfield Hospital
      • Wyoming, Michigan, Forenede Stater, 49519
        • Metro Health Hospital
      • Ypsilanti, Michigan, Forenede Stater, 48197
        • IHA Hematology Oncology Consultants-Ann Arbor
    • Minnesota
      • Bemidji, Minnesota, Forenede Stater, 56601
        • Sanford Clinic North-Bemidgi
      • Brainerd, Minnesota, Forenede Stater, 56401
        • Essentia Health Saint Joseph's Medical Center
      • Burnsville, Minnesota, Forenede Stater, 55337
        • Fairview Ridges Hospital
      • Coon Rapids, Minnesota, Forenede Stater, 55433
        • Mercy Hospital
      • Duluth, Minnesota, Forenede Stater, 55805
        • Essentia Health Cancer Center
      • Duluth, Minnesota, Forenede Stater, 55805
        • Essentia Health Saint Mary's Medical Center
      • Duluth, Minnesota, Forenede Stater, 55805
        • Miller-Dwan Hospital
      • Edina, Minnesota, Forenede Stater, 55435
        • Fairview-Southdale Hospital
      • Fergus Falls, Minnesota, Forenede Stater, 56537
        • Lake Region Healthcare Corporation-Cancer Care
      • Fridley, Minnesota, Forenede Stater, 55432
        • Unity Hospital
      • Hutchinson, Minnesota, Forenede Stater, 55350
        • Hutchinson Area Health Care
      • Maplewood, Minnesota, Forenede Stater, 55109
        • Saint John's Hospital - Healtheast
      • Maplewood, Minnesota, Forenede Stater, 55109
        • Minnesota Oncology Hematology PA-Maplewood
      • Minneapolis, Minnesota, Forenede Stater, 55415
        • Hennepin County Medical Center
      • Minneapolis, Minnesota, Forenede Stater, 55407
        • Abbott-Northwestern Hospital
      • Minneapolis, Minnesota, Forenede Stater, 55454
        • Health Partners Inc
      • New Ulm, Minnesota, Forenede Stater, 56073
        • New Ulm Medical Center
      • Robbinsdale, Minnesota, Forenede Stater, 55422
        • North Memorial Medical Health Center
      • Rochester, Minnesota, Forenede Stater, 55905
        • Mayo Clinic
      • Saint Louis Park, Minnesota, Forenede Stater, 55416
        • Park Nicollet Clinic - Saint Louis Park
      • Saint Louis Park, Minnesota, Forenede Stater, 55416
        • Metro Minnesota Community Oncology Research Consortium
      • Saint Paul, Minnesota, Forenede Stater, 55101
        • Regions Hospital
      • Saint Paul, Minnesota, Forenede Stater, 55102
        • United Hospital
      • Shakopee, Minnesota, Forenede Stater, 55379
        • Saint Francis Regional Medical Center
      • Stillwater, Minnesota, Forenede Stater, 55082
        • Lakeview Hospital
      • Waconia, Minnesota, Forenede Stater, 55387
        • Ridgeview Medical Center
      • Willmar, Minnesota, Forenede Stater, 56201
        • Rice Memorial Hospital
      • Woodbury, Minnesota, Forenede Stater, 55125
        • Minnesota Oncology Hematology PA-Woodbury
    • Mississippi
      • Columbus, Mississippi, Forenede Stater, 39705
        • Baptist Memorial Hospital and Cancer Center-Golden Triangle
      • Jackson, Mississippi, Forenede Stater, 39216
        • University of Mississippi Medical Center
      • Oxford, Mississippi, Forenede Stater, 38655
        • Baptist Memorial Hospital and Cancer Center-Oxford
      • Pascagoula, Mississippi, Forenede Stater, 39581
        • Singing River Hospital
      • Southhaven, Mississippi, Forenede Stater, 38671
        • Baptist Memorial Hospital and Cancer Center-Desoto
    • Missouri
      • Bolivar, Missouri, Forenede Stater, 65613
        • Central Care Cancer Center - Bolivar
      • Bonne Terre, Missouri, Forenede Stater, 63628
        • Parkland Health Center-Bonne Terre
      • Cape Girardeau, Missouri, Forenede Stater, 63703
        • Saint Francis Medical Center
      • Cape Girardeau, Missouri, Forenede Stater, 63703
        • Southeast Cancer Center
      • Chesterfield, Missouri, Forenede Stater, 63017
        • Saint Luke's Hospital
      • Columbia, Missouri, Forenede Stater, 65212
        • University of Missouri - Ellis Fischel
      • Creve Coeur, Missouri, Forenede Stater, 63141
        • Siteman Cancer Center at West County Hospital
      • Independence, Missouri, Forenede Stater, 64057
        • Centerpoint Medical Center LLC
      • Jefferson City, Missouri, Forenede Stater, 65109
        • Capital Region Southwest Campus
      • Joplin, Missouri, Forenede Stater, 64804
        • Freeman Health System
      • Joplin, Missouri, Forenede Stater, 64804
        • Mercy Hospital Joplin
      • Kansas City, Missouri, Forenede Stater, 64128
        • Kansas City Veterans Affairs Medical Center
      • Kansas City, Missouri, Forenede Stater, 64131
        • The University of Kansas Cancer Center-South
      • Kansas City, Missouri, Forenede Stater, 64111
        • Saint Luke's Hospital of Kansas City
      • Kansas City, Missouri, Forenede Stater, 64132
        • Research Medical Center
      • Kansas City, Missouri, Forenede Stater, 64108
        • Truman Medical Center
      • Kansas City, Missouri, Forenede Stater, 64118
        • Heartland Hematology and Oncology Associates Incorporated
      • Kansas City, Missouri, Forenede Stater, 64154
        • The University of Kansas Cancer Center-North
      • Lee's Summit, Missouri, Forenede Stater, 64086
        • Saint Luke's East - Lee's Summit
      • Lee's Summit, Missouri, Forenede Stater, 64064
        • The University of Kansas Cancer Center-Lee's Summit
      • Liberty, Missouri, Forenede Stater, 64068
        • Liberty Radiation Oncology Center
      • Rolla, Missouri, Forenede Stater, 65401
        • Delbert Day Cancer Institute at PCRMC
      • Rolla, Missouri, Forenede Stater, 65401
        • Mercy Clinic-Rolla-Cancer and Hematology
      • Saint Joseph, Missouri, Forenede Stater, 64507
        • Heartland Regional Medical Center
      • Saint Louis, Missouri, Forenede Stater, 63110
        • Washington University School of Medicine
      • Saint Louis, Missouri, Forenede Stater, 63131
        • Missouri Baptist Medical Center
      • Saint Louis, Missouri, Forenede Stater, 63141
        • Mercy Hospital Saint Louis
      • Saint Louis, Missouri, Forenede Stater, 63109
        • Saint Louis Cancer and Breast Institute-South City
      • Saint Peters, Missouri, Forenede Stater, 63376
        • Siteman Cancer Center at Saint Peters Hospital
      • Sainte Genevieve, Missouri, Forenede Stater, 63670
        • Sainte Genevieve County Memorial Hospital
      • Springfield, Missouri, Forenede Stater, 65807
        • CoxHealth South Hospital
      • Springfield, Missouri, Forenede Stater, 65804
        • Mercy Hospital Springfield
      • Sullivan, Missouri, Forenede Stater, 63080
        • Missouri Baptist Sullivan Hospital
      • Sunset Hills, Missouri, Forenede Stater, 63127
        • Missouri Baptist Outpatient Center-Sunset Hills
    • Montana
      • Anaconda, Montana, Forenede Stater, 59711
        • Community Hospital of Anaconda
      • Billings, Montana, Forenede Stater, 59101
        • Billings Clinic Cancer Center
      • Billings, Montana, Forenede Stater, 59101
        • Saint Vincent Healthcare
      • Billings, Montana, Forenede Stater, 59102
        • Montana Cancer Consortium NCORP
      • Bozeman, Montana, Forenede Stater, 59715
        • Bozeman Deaconess Hospital
      • Butte, Montana, Forenede Stater, 59701
        • Saint James Community Hospital and Cancer Treatment Center
      • Great Falls, Montana, Forenede Stater, 59405
        • Great Falls Clinic
      • Great Falls, Montana, Forenede Stater, 59405
        • Benefis Healthcare- Sletten Cancer Institute
      • Helena, Montana, Forenede Stater, 59601
        • Saint Peter's Community Hospital
      • Kalispell, Montana, Forenede Stater, 59901
        • Kalispell Regional Medical Center
      • Missoula, Montana, Forenede Stater, 59804
        • Community Medical Hospital
      • Missoula, Montana, Forenede Stater, 59802
        • Saint Patrick Hospital - Community Hospital
    • Nebraska
      • Grand Island, Nebraska, Forenede Stater, 68803
        • CHI Health Saint Francis
      • Kearney, Nebraska, Forenede Stater, 68847
        • CHI Health Good Samaritan
      • Lincoln, Nebraska, Forenede Stater, 68506
        • Nebraska Hematology and Oncology
      • Lincoln, Nebraska, Forenede Stater, 68510
        • Nebraska Cancer Research Center
      • Lincoln, Nebraska, Forenede Stater, 68510
        • Saint Elizabeth Regional Medical Center
      • Lincoln, Nebraska, Forenede Stater, 68510
        • Southeast Nebraska Cancer Center
      • Norfolk, Nebraska, Forenede Stater, 68701
        • Faith Regional Health Services Carson Cancer Center
      • North Platte, Nebraska, Forenede Stater, 69101
        • Great Plains Health Callahan Cancer Center
      • Omaha, Nebraska, Forenede Stater, 68114
        • Nebraska Methodist Hospital
      • Omaha, Nebraska, Forenede Stater, 68198
        • University of Nebraska Medical Center
      • Omaha, Nebraska, Forenede Stater, 68124
        • Alegent Health Bergan Mercy Medical Center
      • Omaha, Nebraska, Forenede Stater, 68122
        • Alegent Health Immanuel Medical Center
      • Omaha, Nebraska, Forenede Stater, 68130
        • Alegent Health Lakeside Hospital
      • Omaha, Nebraska, Forenede Stater, 68131
        • Creighton University Medical Center
      • Omaha, Nebraska, Forenede Stater, 68106
        • Missouri Valley Cancer Consortium
      • Omaha, Nebraska, Forenede Stater, 68124
        • Nebraska Cancer Specialists - Omaha
      • Papillion, Nebraska, Forenede Stater, 68046
        • Midlands Community Hospital
      • Scottsbluff, Nebraska, Forenede Stater, 69361
        • Regional West Medical Center Cancer Center
    • Nevada
      • Carson City, Nevada, Forenede Stater, 89703
        • Carson Tahoe Regional Medical Center
      • Henderson, Nevada, Forenede Stater, 89052
        • Comprehensive Cancer Centers of Nevada - Henderson
      • Henderson, Nevada, Forenede Stater, 89052
        • Cancer and Blood Specialists-Henderson
      • Henderson, Nevada, Forenede Stater, 89052
        • Las Vegas Cancer Center-Henderson
      • Henderson, Nevada, Forenede Stater, 89074
        • Comprehensive Cancer Centers of Nevada-Southeast Henderson
      • Henderson, Nevada, Forenede Stater, 89074
        • 21st Century Oncology-Henderson
      • Henderson, Nevada, Forenede Stater, 89052
        • Nevada Cancer Specialists-Saint Rose
      • Las Vegas, Nevada, Forenede Stater, 89144
        • Summerlin Hospital Medical Center
      • Las Vegas, Nevada, Forenede Stater, 89128
        • Comprehensive Cancer Centers of Nevada - Northwest
      • Las Vegas, Nevada, Forenede Stater, 89148
        • Comprehensive Cancer Centers of Nevada
      • Las Vegas, Nevada, Forenede Stater, 89169
        • Comprehensive Cancer Centers of Nevada - Central Valley
      • Las Vegas, Nevada, Forenede Stater, 89106
        • Cancer and Blood Specialists-Shadow
      • Las Vegas, Nevada, Forenede Stater, 89109
        • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
      • Las Vegas, Nevada, Forenede Stater, 89113
        • HealthCare Partners Medical Group Oncology/Hematology-San Martin
      • Las Vegas, Nevada, Forenede Stater, 89121
        • Cancer Therapy and Integrative Medicine
      • Las Vegas, Nevada, Forenede Stater, 89128
        • Cancer and Blood Specialists-Tenaya
      • Las Vegas, Nevada, Forenede Stater, 89128
        • HealthCare Partners Medical Group Oncology/Hematology-Tenaya
      • Las Vegas, Nevada, Forenede Stater, 89148-2405
        • Las Vegas Cancer Center-Medical Center
      • Las Vegas, Nevada, Forenede Stater, 89149
        • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
      • Las Vegas, Nevada, Forenede Stater, 89109
        • 21st Century Oncology
      • Las Vegas, Nevada, Forenede Stater, 89106
        • Nevada Cancer Research Foundation CCOP
      • Las Vegas, Nevada, Forenede Stater, 89148
        • Nevada Cancer Specialists-Fort Apache
      • Las Vegas, Nevada, Forenede Stater, 89128
        • Ann M Wierman MD LTD
      • Las Vegas, Nevada, Forenede Stater, 89128
        • Nevada Cancer Specialists-Tenaya
      • Las Vegas, Nevada, Forenede Stater, 89102
        • Nevada Cancer Specialists?Oakey
      • Reno, Nevada, Forenede Stater, 89502
        • Renown Regional Medical Center
      • Reno, Nevada, Forenede Stater, 89503
        • Saint Mary's Regional Medical Center
      • Reno, Nevada, Forenede Stater, 89509
        • Radiation Oncology Associates
      • Reno, Nevada, Forenede Stater, 89503
        • Alpine Hematology-Oncology
      • Reno, Nevada, Forenede Stater, 89519
        • Reno Oncology Consultants
    • New Hampshire
      • Concord, New Hampshire, Forenede Stater, 03301
        • New Hampshire Oncology Hematology PA-Concord
      • Hooksett, New Hampshire, Forenede Stater, 03106
        • New Hampshire Oncology Hematology PA-Hooksett
      • Laconia, New Hampshire, Forenede Stater, 03246
        • LRGHealthcare-Lakes Region General Hospital
      • Lebanon, New Hampshire, Forenede Stater, 03756
        • Dartmouth Hitchcock Medical Center
      • Manchester, New Hampshire, Forenede Stater, 03102
        • Norris Cotton Cancer Center-Manchester
    • New Jersey
      • East Orange, New Jersey, Forenede Stater, 07018-1095
        • Veterans Adminstration New Jersey Health Care System
      • Mount Holly, New Jersey, Forenede Stater, 08060
        • Virtua Memorial
      • Neptune, New Jersey, Forenede Stater, 07753
        • Jersey Shore Medical Center
      • Newark, New Jersey, Forenede Stater, 07112
        • Newark Beth Israel Medical Center
      • Paramus, New Jersey, Forenede Stater, 07652
        • The Valley Hospital-Luckow Pavilion
      • Red Bank, New Jersey, Forenede Stater, 07701
        • Riverview Medical Center/Booker Cancer Center
      • Ridgewood, New Jersey, Forenede Stater, 07450
        • Valley Hospital
      • Somerville, New Jersey, Forenede Stater, 08876
        • Robert Wood Johnson University Hospital Somerset
      • Voorhees, New Jersey, Forenede Stater, 08043
        • Virtua Voorhees
      • Westwood, New Jersey, Forenede Stater, 07675
        • Valley Health System-Hematology/Oncology
    • New Mexico
      • Albuquerque, New Mexico, Forenede Stater, 87102
        • University of New Mexico Cancer Center
      • Albuquerque, New Mexico, Forenede Stater, 87102
        • Lovelace Medical Center-Saint Joseph Square
      • Albuquerque, New Mexico, Forenede Stater, 87102
        • Lovelace Medical Center-Downtown
      • Albuquerque, New Mexico, Forenede Stater, 87109
        • New Mexico Oncology Hematology Consultants
      • Las Cruces, New Mexico, Forenede Stater, 88011
        • Memorial Medical Center - Las Cruces
    • New York
      • Albany, New York, Forenede Stater, 12208
        • New York Oncology Hematology PC -Albany Medical Center
      • Bronx, New York, Forenede Stater, 10461
        • Montefiore Medical Center-Einstein Campus
      • Bronx, New York, Forenede Stater, 10467
        • Montefiore Medical Center - Moses Campus
      • Bronx, New York, Forenede Stater, 10461
        • Montefiore Medical Center-Weiler Hospital
      • Bronx, New York, Forenede Stater, 10468
        • Bronx Veterans Administration Medical Center
      • Brooklyn, New York, Forenede Stater, 11215
        • New York-Presbyterian/Brooklyn Methodist Hospital
      • Buffalo, New York, Forenede Stater, 14263
        • Roswell Park Cancer Institute
      • Cooperstown, New York, Forenede Stater, 13326
        • Mary Imogene Bassett Hospital
      • Elmira, New York, Forenede Stater, 14905
        • Arnot Ogden Medical Center/Falck Cancer Center
      • Glens Falls, New York, Forenede Stater, 12801
        • Glens Falls Hospital
      • Middletown, New York, Forenede Stater, 10940
        • Orange Regional Medical Center
      • New York, New York, Forenede Stater, 10032
        • Columbia University/Herbert Irving Cancer Center
      • New York, New York, Forenede Stater, 10003
        • Mount Sinai Union Square
      • Rochester, New York, Forenede Stater, 14642
        • University of Rochester
      • Stony Brook, New York, Forenede Stater, 11794
        • Stony Brook University Medical Center
      • Syracuse, New York, Forenede Stater, 13210
        • State University of New York Upstate Medical University
      • Utica, New York, Forenede Stater, 13502
        • Faxton-Saint Luke's Healthcare
    • North Carolina
      • Asheboro, North Carolina, Forenede Stater, 27203
        • Randolph Hospital
      • Asheville, North Carolina, Forenede Stater, 28801
        • Cancer Care of Western North Carolina
      • Asheville, North Carolina, Forenede Stater, 28801
        • Mission Hospital Inc-Memorial Campus
      • Burlington, North Carolina, Forenede Stater, 27215
        • Cone Health Cancer Center at Alamance Regional
      • Charlotte, North Carolina, Forenede Stater, 28204
        • Novant Health Presbyterian Medical Center
      • Charlotte, North Carolina, Forenede Stater, 28207
        • Oncology Specialists of Charlotte
      • Charlotte, North Carolina, Forenede Stater, 28262
        • Southern Oncology Specialists-Charlotte
      • Clinton, North Carolina, Forenede Stater, 28328
        • Southeastern Medical Oncology Center-Clinton
      • Durham, North Carolina, Forenede Stater, 27710
        • Duke University Medical Center
      • Fayetteville, North Carolina, Forenede Stater, 28304
        • Cape Fear Valley Health System
      • Goldsboro, North Carolina, Forenede Stater, 27534
        • Southeastern Medical Oncology Center-Goldsboro
      • Goldsboro, North Carolina, Forenede Stater, 27534
        • Wayne Memorial Hospital
      • Greensboro, North Carolina, Forenede Stater, 27403
        • Cone Health Cancer Center
      • Hendersonville, North Carolina, Forenede Stater, 28791
        • Hendersonville Hematology and Oncology at Pardee
      • Hendersonville, North Carolina, Forenede Stater, 28791
        • Margaret R Pardee Memorial Hospital
      • High Point, North Carolina, Forenede Stater, 27262
        • High Point Regional Hospital
      • Huntersville, North Carolina, Forenede Stater, 28078
        • Southern Oncology Specialists-Huntersville
      • Huntersville, North Carolina, Forenede Stater, 28078
        • Lake Norman Hematology Oncology Specialists-Huntersville
      • Jacksonville, North Carolina, Forenede Stater, 28546
        • Southeastern Medical Oncology Center-Jacksonville
      • Kinston, North Carolina, Forenede Stater, 28501
        • Vidant Oncology-Kinston
      • Matthews, North Carolina, Forenede Stater, 28105
        • Novant Health Cancer Specialists-Matthews
      • Matthews, North Carolina, Forenede Stater, 28105
        • Matthews Radiation Oncology Center
      • Mooresville, North Carolina, Forenede Stater, 28117
        • Lake Norman Hematology Oncology Specialists-Mooresville
      • Pinehurst, North Carolina, Forenede Stater, 28374
        • FirstHealth of the Carolinas-Moore Regional Hospital
      • Raleigh, North Carolina, Forenede Stater, 27609
        • Duke Raleigh Hospital
      • Reidsville, North Carolina, Forenede Stater, 27320
        • Annie Penn Memorial Hospital
      • Wilson, North Carolina, Forenede Stater, 27893
        • Southeastern Medical Oncology Center-Wilson
    • North Dakota
      • Bismarck, North Dakota, Forenede Stater, 58501
        • Sanford Bismarck Medical Center
      • Fargo, North Dakota, Forenede Stater, 58122
        • Sanford Broadway Medical Center
      • Fargo, North Dakota, Forenede Stater, 58122
        • Sanford Clinic North-Fargo
      • Fargo, North Dakota, Forenede Stater, 58122
        • Roger Maris Cancer Center
      • Minot, North Dakota, Forenede Stater, 58701
        • Trinity Cancer Care Center
    • Ohio
      • Beachwood, Ohio, Forenede Stater, 44122
        • UHHS-Chagrin Highlands Medical Center
      • Beachwood, Ohio, Forenede Stater, 44122
        • Cleveland Clinic Cancer Center Beachwood
      • Beavercreek, Ohio, Forenede Stater, 45431
        • Indu and Raj Soin Medical Center
      • Belpre, Ohio, Forenede Stater, 45714
        • Strecker Cancer Center-Belpre
      • Canton, Ohio, Forenede Stater, 44710
        • Aultman Health Foundation
      • Canton, Ohio, Forenede Stater, 44708
        • Mercy Medical Center
      • Chardon, Ohio, Forenede Stater, 44024
        • Geauga Hospital
      • Chillicothe, Ohio, Forenede Stater, 45601
        • Adena Regional Medical Center
      • Cincinnati, Ohio, Forenede Stater, 45220
        • Good Samaritan Hospital - Cincinnati
      • Cincinnati, Ohio, Forenede Stater, 45242
        • Bethesda North Hospital
      • Cincinnati, Ohio, Forenede Stater, 45242
        • Oncology Hematology Care Inc-Blue Ash
      • Cincinnati, Ohio, Forenede Stater, 45202
        • Oncology Hematology Care Inc-Eden Park
      • Cincinnati, Ohio, Forenede Stater, 45211
        • Oncology Hematology Care Inc-Mercy West
      • Cincinnati, Ohio, Forenede Stater, 45236
        • Oncology Hematology Care Inc-Kenwood
      • Cincinnati, Ohio, Forenede Stater, 45219
        • University of Cincinnati/Barrett Cancer Center
      • Cincinnati, Ohio, Forenede Stater, 45230
        • Oncology Hematology Care Inc - Anderson
      • Cincinnati, Ohio, Forenede Stater, 45247
        • TriHealth Cancer Institute-Westside
      • Cincinnati, Ohio, Forenede Stater, 45255
        • TriHealth Cancer Institute-Anderson
      • Cleveland, Ohio, Forenede Stater, 44106
        • Case Western Reserve University
      • Cleveland, Ohio, Forenede Stater, 44109
        • MetroHealth Medical Center
      • Cleveland, Ohio, Forenede Stater, 44195
        • Cleveland Clinic Foundation
      • Cleveland, Ohio, Forenede Stater, 44111
        • Cleveland Clinic Cancer Center/Fairview Hospital
      • Columbus, Ohio, Forenede Stater, 43214
        • Riverside Methodist Hospital
      • Columbus, Ohio, Forenede Stater, 43210
        • Ohio State University Comprehensive Cancer Center
      • Columbus, Ohio, Forenede Stater, 43219
        • The Mark H Zangmeister Center
      • Columbus, Ohio, Forenede Stater, 43214
        • Columbus Oncology and Hematology Associates Inc
      • Columbus, Ohio, Forenede Stater, 43228
        • Doctors Hospital
      • Columbus, Ohio, Forenede Stater, 43215
        • Grant Medical Center
      • Columbus, Ohio, Forenede Stater, 43222
        • Mount Carmel Health Center West
      • Columbus, Ohio, Forenede Stater, 43215
        • Columbus NCI Community Oncology Research Program
      • Dayton, Ohio, Forenede Stater, 45406
        • Good Samaritan Hospital - Dayton
      • Dayton, Ohio, Forenede Stater, 45415
        • Dayton Physicians LLC-Samaritan North
      • Dayton, Ohio, Forenede Stater, 45415
        • Samaritan North Health Center
      • Delaware, Ohio, Forenede Stater, 43015
        • Delaware Health Center-Grady Cancer Center
      • Delaware, Ohio, Forenede Stater, 43015
        • Grady Memorial Hospital
      • Elyria, Ohio, Forenede Stater, 44035
        • Mercy Cancer Center-Elyria
      • Fairfield, Ohio, Forenede Stater, 45014
        • Oncology Hematology Care Inc-Healthplex
      • Findlay, Ohio, Forenede Stater, 45840
        • Blanchard Valley Hospital
      • Findlay, Ohio, Forenede Stater, 45840
        • Armes Family Cancer Center
      • Findlay, Ohio, Forenede Stater, 45840
        • Orion Cancer Care
      • Independence, Ohio, Forenede Stater, 44131
        • Cleveland Clinic Cancer Center Independence
      • Kettering, Ohio, Forenede Stater, 45429
        • Kettering Medical Center
      • Lancaster, Ohio, Forenede Stater, 43130
        • Fairfield Medical Center
      • Mansfield, Ohio, Forenede Stater, 44906
        • Cleveland Clinic Cancer Center Mansfield
      • Marietta, Ohio, Forenede Stater, 45750
        • Marietta Memorial Hospital
      • Maumee, Ohio, Forenede Stater, 43537
        • Toledo Clinic Cancer Centers-Maumee
      • Mayfield Heights, Ohio, Forenede Stater, 44124
        • Hillcrest Hospital Cancer Center
      • Mayfield Heights, Ohio, Forenede Stater, 44124
        • Ireland Cancer Center Landerbrook Health Center
      • Mentor, Ohio, Forenede Stater, 44060
        • Lake University Ireland Cancer Center
      • Middleburg Heights, Ohio, Forenede Stater, 44130
        • Southwest General Health Center Ireland Cancer Center
      • Mount Vernon, Ohio, Forenede Stater, 43050
        • Knox Community Hospital
      • Newark, Ohio, Forenede Stater, 43055
        • Licking Memorial Hospital
      • Portsmouth, Ohio, Forenede Stater, 45662
        • Southern Ohio Medical Center
      • Sandusky, Ohio, Forenede Stater, 44870
        • North Coast Cancer Care
      • Sandusky, Ohio, Forenede Stater, 44870
        • Ireland Cancer Center at Firelands Regional Medical Center
      • Springfield, Ohio, Forenede Stater, 45505
        • Springfield Regional Medical Center
      • Strongsville, Ohio, Forenede Stater, 44136
        • Cleveland Clinic Cancer Center Strongsville
      • Sylvania, Ohio, Forenede Stater, 43560
        • Flower Hospital
      • Toledo, Ohio, Forenede Stater, 43623
        • Toledo Clinic Cancer Centers-Toledo
      • Toledo, Ohio, Forenede Stater, 43614
        • University of Toledo
      • Toledo, Ohio, Forenede Stater, 43606
        • The Toledo Hospital/Toledo Children's Hospital
      • Troy, Ohio, Forenede Stater, 45373
        • Upper Valley Medical Center
      • Wadsworth, Ohio, Forenede Stater, 44281
        • University Hospitals Sharon Health Center
      • Warrensville Heights, Ohio, Forenede Stater, 44122
        • South Pointe Hospital
      • West Chester, Ohio, Forenede Stater, 45069
        • University Pointe
      • Westerville, Ohio, Forenede Stater, 43081
        • Saint Ann's Hospital
      • Westlake, Ohio, Forenede Stater, 44145
        • UH Seidman Cancer Center at Saint John Medical Center
      • Westlake, Ohio, Forenede Stater, 44145
        • UHHS-Westlake Medical Center
      • Wooster, Ohio, Forenede Stater, 44691
        • Cleveland Clinic Wooster Family Health and Surgery Center
      • Zanesville, Ohio, Forenede Stater, 43701
        • Genesis Healthcare System Cancer Care Center
    • Oklahoma
      • Lawton, Oklahoma, Forenede Stater, 73505
        • Cancer Centers of Southwest Oklahoma Research
      • Oklahoma City, Oklahoma, Forenede Stater, 73104
        • University of Oklahoma Health Sciences Center
      • Oklahoma City, Oklahoma, Forenede Stater, 73120
        • Mercy Hospital Oklahoma City
      • Tulsa, Oklahoma, Forenede Stater, 74146
        • Oklahoma Cancer Specialists and Research Institute-Tulsa
    • Oregon
      • Bend, Oregon, Forenede Stater, 97701
        • Saint Charles Health System
      • Clackamas, Oregon, Forenede Stater, 97015
        • Clackamas Radiation Oncology Center
      • Clackamas, Oregon, Forenede Stater, 97015
        • Providence Oncology and Hematology Care Southeast
      • Coos Bay, Oregon, Forenede Stater, 97420
        • Bay Area Hospital
      • Gresham, Oregon, Forenede Stater, 97030
        • Legacy Mount Hood Medical Center
      • Newberg, Oregon, Forenede Stater, 97132
        • Providence Newberg Medical Center
      • Oregon City, Oregon, Forenede Stater, 97045
        • Providence Willamette Falls Medical Center
      • Portland, Oregon, Forenede Stater, 97239
        • Oregon Health and Science University
      • Portland, Oregon, Forenede Stater, 97210
        • Legacy Good Samaritan Hospital and Medical Center
      • Portland, Oregon, Forenede Stater, 97213
        • Providence Portland Medical Center
      • Portland, Oregon, Forenede Stater, 97225
        • Providence Saint Vincent Medical Center
      • Portland, Oregon, Forenede Stater, 97227
        • Kaiser Permanente Northwest
      • Salem, Oregon, Forenede Stater, 97301
        • Salem Hospital
      • Tualatin, Oregon, Forenede Stater, 97062
        • Legacy Meridian Park Hospital
    • Pennsylvania
      • Allentown, Pennsylvania, Forenede Stater, 18103
        • Lehigh Valley Hospital-Cedar Crest
      • Bethlehem, Pennsylvania, Forenede Stater, 18017
        • Lehigh Valley Hospital - Muhlenberg
      • Bryn Mawr, Pennsylvania, Forenede Stater, 19010
        • Bryn Mawr Hospital
      • Chadds Ford, Pennsylvania, Forenede Stater, 19317
        • Christiana Care Health System-Concord Health Center
      • Danville, Pennsylvania, Forenede Stater, 17822
        • Geisinger Medical Center
      • Ephrata, Pennsylvania, Forenede Stater, 17522
        • Ephrata Cancer Center
      • Ephrata, Pennsylvania, Forenede Stater, 17522
        • Ephrata Community Hospital
      • Gettysburg, Pennsylvania, Forenede Stater, 17325
        • Adams Cancer Center
      • Hanover, Pennsylvania, Forenede Stater, 17331
        • Cherry Tree Cancer Center
      • Harrisburg, Pennsylvania, Forenede Stater, 17109
        • UPMC Pinnacle Cancer Center/Community Osteopathic Campus
      • Hazleton, Pennsylvania, Forenede Stater, 18201
        • Geisinger Medical Center-Cancer Center Hazleton
      • Hershey, Pennsylvania, Forenede Stater, 17033-0850
        • Penn State Milton S Hershey Medical Center
      • Jefferson Hills, Pennsylvania, Forenede Stater, 15025
        • Jefferson Hospital
      • Lebanon, Pennsylvania, Forenede Stater, 17042
        • Sechler Family Cancer Center
      • Lewisburg, Pennsylvania, Forenede Stater, 17837
        • Geisinger Medical Oncology-Lewisburg
      • Lewistown, Pennsylvania, Forenede Stater, 17044
        • Lewistown Hospital
      • Media, Pennsylvania, Forenede Stater, 19063
        • Riddle Memorial Hospital
      • Monroeville, Pennsylvania, Forenede Stater, 15146
        • Forbes Hospital
      • Natrona Heights, Pennsylvania, Forenede Stater, 15065
        • Allegheny Valley Hospital
      • Paoli, Pennsylvania, Forenede Stater, 19301
        • Paoli Memorial Hospital
      • Philadelphia, Pennsylvania, Forenede Stater, 19111
        • Fox Chase Cancer Center
      • Philadelphia, Pennsylvania, Forenede Stater, 19104
        • University of Pennsylvania/Abramson Cancer Center
      • Philadelphia, Pennsylvania, Forenede Stater, 19140
        • Temple University Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15212
        • Allegheny General Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15224
        • West Penn Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15232
        • University of Pittsburgh Cancer Institute (UPCI)
      • Pottstown, Pennsylvania, Forenede Stater, 19464
        • Pottstown Hospital
      • Pottsville, Pennsylvania, Forenede Stater, 17901
        • Geisinger Cancer Services-Pottsville
      • Reading, Pennsylvania, Forenede Stater, 19605
        • Penn State Health Saint Joseph Medical Center
      • Sayre, Pennsylvania, Forenede Stater, 18840
        • Guthrie Medical Group PC-Robert Packer Hospital
      • Scranton, Pennsylvania, Forenede Stater, 18510
        • Community Medical Center
      • Selinsgrove, Pennsylvania, Forenede Stater, 17870
        • Geisinger Medical Oncology-Selinsgrove
      • State College, Pennsylvania, Forenede Stater, 16801
        • Geisinger Medical Group
      • West Chester, Pennsylvania, Forenede Stater, 19380
        • Chester County Hospital
      • West Reading, Pennsylvania, Forenede Stater, 19611
        • Reading Hospital
      • Wexford, Pennsylvania, Forenede Stater, 15090
        • Wexford Health and Wellness Pavilion
      • Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
        • Geisinger Wyoming Valley/Henry Cancer Center
      • Williamsport, Pennsylvania, Forenede Stater, 17701
        • UPMC Susquehanna
      • Wynnewood, Pennsylvania, Forenede Stater, 19096
        • Lankenau Medical Center
      • York, Pennsylvania, Forenede Stater, 17403
        • WellSpan Health-York Cancer Center
      • York, Pennsylvania, Forenede Stater, 17403
        • WellSpan Health-York Hospital
    • Rhode Island
      • Providence, Rhode Island, Forenede Stater, 02903
        • Rhode Island Hospital
      • Providence, Rhode Island, Forenede Stater, 02906
        • Miriam Hospital
    • South Carolina
      • Anderson, South Carolina, Forenede Stater, 29621
        • AnMed Health Cancer Center
      • Charleston, South Carolina, Forenede Stater, 29425
        • Medical University of South Carolina
      • Charleston, South Carolina, Forenede Stater, 29401
        • Roper Hospital
      • Charleston, South Carolina, Forenede Stater, 29403
        • Charleston Hematology Oncology Associates-Roper
      • Charleston, South Carolina, Forenede Stater, 29414
        • Bon Secours Saint Francis Hospital
      • Charleston, South Carolina, Forenede Stater, 29414
        • Lowcountry Hematology Oncology PA-West Ashley
      • Charleston, South Carolina, Forenede Stater, 29414
        • Charleston Hematology Oncology Associates PA-Saint Francis
      • Clinton, South Carolina, Forenede Stater, 29325
        • Greenville Health System Cancer Institute-Laurens
      • Easley, South Carolina, Forenede Stater, 29640
        • Greenville Health System Cancer Institute-Easley
      • Gaffney, South Carolina, Forenede Stater, 29341
        • Gibbs Cancer Center-Gaffney
      • Georgetown, South Carolina, Forenede Stater, 29440
        • Tidelands Georgetown Memorial Hospital
      • Greenville, South Carolina, Forenede Stater, 29607
        • Saint Francis Cancer Center
      • Greenville, South Carolina, Forenede Stater, 29601
        • Saint Francis Hospital
      • Greenville, South Carolina, Forenede Stater, 29605
        • Greenville Health System Cancer Institute-Faris
      • Greenville, South Carolina, Forenede Stater, 29615
        • Greenville Health System Cancer Institute-Eastside
      • Greenville, South Carolina, Forenede Stater, 29605
        • Greenville Health System Cancer Institute-Butternut
      • Greer, South Carolina, Forenede Stater, 29651
        • Gibbs Cancer Center-Pelham
      • Greer, South Carolina, Forenede Stater, 29650
        • Greenville Health System Cancer Institute-Greer
      • Mount Pleasant, South Carolina, Forenede Stater, 29464
        • Lowcountry Hematology Oncology PA-Mount Pleasant
      • Seneca, South Carolina, Forenede Stater, 29672
        • Greenville Health System Cancer Institute-Seneca
      • Spartanburg, South Carolina, Forenede Stater, 29303
        • Spartanburg Medical Center
      • Spartanburg, South Carolina, Forenede Stater, 29307
        • Greenville Health System Cancer Institute-Spartanburg
      • Union, South Carolina, Forenede Stater, 29379
        • MGC Hematology Oncology-Union
      • West Columbia, South Carolina, Forenede Stater, 29169
        • Lexington Medical Center
    • South Dakota
      • Aberdeen, South Dakota, Forenede Stater, 57401
        • Avera Cancer Institute-Aberdeen
      • Rapid City, South Dakota, Forenede Stater, 57701
        • Rapid City Regional Hospital
      • Sioux Falls, South Dakota, Forenede Stater, 57105
        • Avera Cancer Institute
      • Sioux Falls, South Dakota, Forenede Stater, 57117-5134
        • Sanford USD Medical Center - Sioux Falls
      • Sioux Falls, South Dakota, Forenede Stater, 57104
        • Sanford Cancer Center Oncology Clinic
    • Tennessee
      • Bartlett, Tennessee, Forenede Stater, 38133
        • Boston Baskin Cancer Center-Bartlett
      • Cookeville, Tennessee, Forenede Stater, 38501
        • Cookeville Regional Medical Center
      • Franklin, Tennessee, Forenede Stater, 37067
        • Vanderbilt-Ingram Cancer Center Cool Springs
      • Knoxville, Tennessee, Forenede Stater, 37916
        • Thompson Cancer Survival Center
      • Knoxville, Tennessee, Forenede Stater, 37932
        • Thompson Cancer Survival Center - West
      • Memphis, Tennessee, Forenede Stater, 38120
        • Baptist Memorial Hospital and Cancer Center-Memphis
      • Memphis, Tennessee, Forenede Stater, 38120
        • Family Cancer Center-Memphis
      • Nashville, Tennessee, Forenede Stater, 37232
        • Vanderbilt University/Ingram Cancer Center
      • Nashville, Tennessee, Forenede Stater, 37204
        • Vanderbilt Breast Center at One Hundred Oaks
      • Nashville, Tennessee, Forenede Stater, 37208
        • Meharry Medical College
      • Oak Ridge, Tennessee, Forenede Stater, 37830
        • Thompson Oncology Group-Oak Ridge
    • Texas
      • Amarillo, Texas, Forenede Stater, 79106
        • The Don and Sybil Harrington Cancer Center
      • Austin, Texas, Forenede Stater, 78701
        • Dell Seton Medical Center at The University of Texas
      • Dallas, Texas, Forenede Stater, 75235
        • Parkland Memorial Hospital
      • Dallas, Texas, Forenede Stater, 75390
        • UT Southwestern/Simmons Cancer Center-Dallas
      • Dallas, Texas, Forenede Stater, 75246
        • Baylor University Medical Center
      • Fort Sam Houston, Texas, Forenede Stater, 78234
        • Brooke Army Medical Center
      • Galveston, Texas, Forenede Stater, 77555-0565
        • University of Texas Medical Branch
      • Houston, Texas, Forenede Stater, 77030
        • M D Anderson Cancer Center
      • Houston, Texas, Forenede Stater, 77026-1967
        • Lyndon Baines Johnson General Hospital
      • Houston, Texas, Forenede Stater, 77030
        • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
      • Houston, Texas, Forenede Stater, 77030
        • Memorial Hermann Texas Medical Center
      • Houston, Texas, Forenede Stater, 77030
        • Michael E DeBakey VA Medical Center
      • Houston, Texas, Forenede Stater, 77030
        • The Methodist Hospital System
      • Houston, Texas, Forenede Stater, 77030
        • Ben Taub General Hospital
      • League City, Texas, Forenede Stater, 77573
        • UTMB Cancer Center at Victory Lakes
      • Lubbock, Texas, Forenede Stater, 79415
        • University Medical Center
      • Lubbock, Texas, Forenede Stater, 79410
        • Covenant Medical Center-Lakeside
      • Lubbock, Texas, Forenede Stater, 79430
        • Texas Tech University Health Sciences Center-Lubbock
      • San Antonio, Texas, Forenede Stater, 78229
        • University of Texas Health Science Center at San Antonio
    • Utah
      • American Fork, Utah, Forenede Stater, 84003
        • American Fork Hospital / Huntsman Intermountain Cancer Center
      • Cedar City, Utah, Forenede Stater, 84720
        • Sandra L Maxwell Cancer Center
      • Logan, Utah, Forenede Stater, 84321
        • Logan Regional Hospital
      • Murray, Utah, Forenede Stater, 84107
        • Intermountain Medical Center
      • Ogden, Utah, Forenede Stater, 84403
        • McKay-Dee Hospital Center
      • Provo, Utah, Forenede Stater, 84604
        • Utah Valley Regional Medical Center
      • Saint George, Utah, Forenede Stater, 84770
        • Dixie Medical Center Regional Cancer Center
      • Salt Lake City, Utah, Forenede Stater, 84112
        • Huntsman Cancer Institute/University of Utah
      • Salt Lake City, Utah, Forenede Stater, 84106
        • Utah Cancer Specialists-Salt Lake City
      • Salt Lake City, Utah, Forenede Stater, 84143
        • LDS Hospital
    • Vermont
      • Berlin, Vermont, Forenede Stater, 05602
        • Central Vermont Medical Center/National Life Cancer Treatment
      • Burlington, Vermont, Forenede Stater, 05401
        • University of Vermont Medical Center
      • Burlington, Vermont, Forenede Stater, 05405
        • University of Vermont College of Medicine
    • Virginia
      • Burke, Virginia, Forenede Stater, 22015
        • Kaiser Permanente-Burke Medical Center
      • Charlottesville, Virginia, Forenede Stater, 22908
        • University of Virginia Cancer Center
      • Fredericksburg, Virginia, Forenede Stater, 22408
        • Hematology Oncology Associates of Fredericksburg Inc
      • Lynchburg, Virginia, Forenede Stater, 24501
        • Lynchburg Hematology-Oncology Clinic
      • Martinsville, Virginia, Forenede Stater, 24115
        • Sovah Health Martinsville
      • McLean, Virginia, Forenede Stater, 22102
        • Kaiser Permanente Tysons Corner Medical Center
      • Mechanicsville, Virginia, Forenede Stater, 23116
        • Bon Secours Memorial Regional Medical Center
      • Midlothian, Virginia, Forenede Stater, 23114
        • Bon Secours Saint Francis Medical Center
      • Richmond, Virginia, Forenede Stater, 23298
        • Virginia Commonwealth University/Massey Cancer Center
      • Richmond, Virginia, Forenede Stater, 23230
        • Virginia Cancer Institute
      • Richmond, Virginia, Forenede Stater, 23226
        • Bon Secours Saint Mary's Hospital
      • South Hill, Virginia, Forenede Stater, 23970
        • VCU Community Memorial Health Center
      • Winchester, Virginia, Forenede Stater, 22601
        • Shenandoah Oncology PC
    • Washington
      • Auburn, Washington, Forenede Stater, 98001
        • MultiCare Auburn Medical Center
      • Bellevue, Washington, Forenede Stater, 98004
        • Overlake Hospital Medical Center
      • Bellingham, Washington, Forenede Stater, 98225
        • PeaceHealth Saint Joseph Medical Center
      • Bremerton, Washington, Forenede Stater, 98310
        • Harrison HealthPartners Hematology and Oncology-Bremerton
      • Bremerton, Washington, Forenede Stater, 98310
        • Harrison Medical Center
      • Burien, Washington, Forenede Stater, 98166
        • Highline Medical Center-Main Campus
      • Edmonds, Washington, Forenede Stater, 98026
        • Swedish Medical Center-Edmonds
      • Everett, Washington, Forenede Stater, 98201
        • Providence Regional Cancer Partnership
      • Gig Harbor, Washington, Forenede Stater, 98332
        • Tacoma/Valley Radiation Oncology Centers-Gig Harbor
      • Gig Harbor, Washington, Forenede Stater, 98335
        • MultiCare Gig Harbor Medical Park
      • Issaquah, Washington, Forenede Stater, 98029
        • Swedish Cancer Institute-Issaquah
      • Kennewick, Washington, Forenede Stater, 99336
        • Kadlec Clinic Hematology and Oncology
      • Kennewick, Washington, Forenede Stater, 99336
        • Northwest Cancer Clinic
      • Kirkland, Washington, Forenede Stater, 98034
        • Seattle Cancer Care Alliance at EvergreenHealth
      • Longview, Washington, Forenede Stater, 98632
        • PeaceHealth Saint John Medical Center
      • Mount Vernon, Washington, Forenede Stater, 98273
        • Skagit Valley Hospital Regional Cancer Care Center
      • Mount Vernon, Washington, Forenede Stater, 98274
        • Skagit Valley Hospital
      • Port Townsend, Washington, Forenede Stater, 98368
        • Jefferson Healthcare
      • Poulsbo, Washington, Forenede Stater, 98370
        • Harrison HealthPartners Hematology and Oncology-Poulsbo
      • Poulsbo, Washington, Forenede Stater, 98370
        • Peninsula Cancer Center
      • Puyallup, Washington, Forenede Stater, 98372
        • MultiCare Good Samaritan Hospital
      • Puyallup, Washington, Forenede Stater, 98372
        • Tacoma/Valley Radiation Oncology Centers-Puyallup
      • Seattle, Washington, Forenede Stater, 98109
        • Fred Hutchinson Cancer Research Center
      • Seattle, Washington, Forenede Stater, 98109
        • Seattle Cancer Care Alliance
      • Seattle, Washington, Forenede Stater, 98195
        • University of Washington Medical Center
      • Seattle, Washington, Forenede Stater, 98101
        • Virginia Mason Medical Center
      • Seattle, Washington, Forenede Stater, 98107
        • Swedish Medical Center-Ballard Campus
      • Seattle, Washington, Forenede Stater, 98112
        • Kaiser Permanente Washington
      • Seattle, Washington, Forenede Stater, 98122-4307
        • Swedish Medical Center-First Hill
      • Seattle, Washington, Forenede Stater, 98133
        • Seattle Cancer Care Alliance at Northwest Hospital
      • Tacoma, Washington, Forenede Stater, 98405
        • Northwest Medical Specialties PLLC
      • Tacoma, Washington, Forenede Stater, 98405
        • MultiCare Tacoma General Hospital
      • Tacoma, Washington, Forenede Stater, 98405
        • Tacoma/Valley Radiation Oncology Centers-Saint Joe's
      • Tacoma, Washington, Forenede Stater, 97405
        • Tacoma/Valley Radiation Oncology Centers-Jackson Hall
      • Tacoma, Washington, Forenede Stater, 98405
        • Franciscan Research Center-Northwest Medical Plaza
      • Tacoma, Washington, Forenede Stater, 98405
        • Northwest NCI Community Oncology Research Program
      • Tacoma, Washington, Forenede Stater, 98405
        • Saint Joseph Medical Center
      • Vancouver, Washington, Forenede Stater, 98686
        • Legacy Salmon Creek Hospital
      • Vancouver, Washington, Forenede Stater, 98664
        • PeaceHealth Southwest Medical Center
      • Walla Walla, Washington, Forenede Stater, 99362
        • Providence Saint Mary Regional Cancer Center
      • Wenatchee, Washington, Forenede Stater, 98801
        • Wenatchee Valley Hospital and Clinics
    • West Virginia
      • Bridgeport, West Virginia, Forenede Stater, 26330
        • United Hospital Center
      • Charleston, West Virginia, Forenede Stater, 25304
        • West Virginia University Charleston Division
      • Huntington, West Virginia, Forenede Stater, 25701
        • Edwards Comprehensive Cancer Center
      • Huntington, West Virginia, Forenede Stater, 25702
        • Saint Mary's Medical Center
      • Morgantown, West Virginia, Forenede Stater, 26506
        • West Virginia University Healthcare
      • Parkersburg, West Virginia, Forenede Stater, 26101
        • Camden Clark Medical Center
    • Wisconsin
      • Antigo, Wisconsin, Forenede Stater, 54409
        • Langlade Hospital and Cancer Center
      • Appleton, Wisconsin, Forenede Stater, 54913
        • Fox Valley Hematology and Oncology SC-Appleton
      • Burlington, Wisconsin, Forenede Stater, 53105
        • Aurora Cancer Care-Southern Lakes VLCC
      • Chippewa Falls, Wisconsin, Forenede Stater, 54729
        • Marshfield Clinic-Chippewa Center
      • Eau Claire, Wisconsin, Forenede Stater, 54701
        • HSHS Sacred Heart Hospital
      • Eau Claire, Wisconsin, Forenede Stater, 54701
        • Marshfield Clinic Cancer Center at Sacred Heart
      • Eau Claire, Wisconsin, Forenede Stater, 54701
        • Marshfield Clinic Cancer Center - Eau Claire
      • Fond Du Lac, Wisconsin, Forenede Stater, 54937
        • Aurora Health Center-Fond du Lac
      • Germantown, Wisconsin, Forenede Stater, 53022
        • Aurora Health Care Germantown Health Center
      • Grafton, Wisconsin, Forenede Stater, 53024
        • Aurora Cancer Care-Grafton
      • Green Bay, Wisconsin, Forenede Stater, 54311
        • Aurora BayCare Medical Center
      • Green Bay, Wisconsin, Forenede Stater, 54301
        • Saint Vincent Hospital Cancer Center Green Bay
      • Green Bay, Wisconsin, Forenede Stater, 54303
        • Saint Vincent Hospital Cancer Center at Saint Mary's
      • Green Bay, Wisconsin, Forenede Stater, 54303
        • Green Bay Oncology Limited at Saint Mary's Hospital
      • Green Bay, Wisconsin, Forenede Stater, 54301-3526
        • Green Bay Oncology at Saint Vincent Hospital
      • Janesville, Wisconsin, Forenede Stater, 53547
        • Mercy Health System
      • Johnson Creek, Wisconsin, Forenede Stater, 53038
        • UW Cancer Center Johnson Creek
      • Kenosha, Wisconsin, Forenede Stater, 53142
        • Aurora Cancer Care-Kenosha South
      • La Crosse, Wisconsin, Forenede Stater, 54601
        • Gundersen Lutheran Medical Center
      • Ladysmith, Wisconsin, Forenede Stater, 54848
        • Marshfield Clinic - Ladysmith Center
      • Madison, Wisconsin, Forenede Stater, 53792
        • University of Wisconsin Hospital and Clinics
      • Manitowoc, Wisconsin, Forenede Stater, 54221
        • Holy Family Memorial Hospital
      • Marinette, Wisconsin, Forenede Stater, 54143
        • Aurora Bay Area Medical Group-Marinette
      • Marinette, Wisconsin, Forenede Stater, 54143
        • Vince Lombardi Cancer Clinic-Marinette
      • Marinette, Wisconsin, Forenede Stater, 54143
        • Saint Vincent Hospital Cancer Center at Marinette
      • Marshfield, Wisconsin, Forenede Stater, 54449
        • Marshfield Clinic
      • Marshfield, Wisconsin, Forenede Stater, 54449
        • Marshfield Medical Center
      • Menomonee Falls, Wisconsin, Forenede Stater, 53051
        • Community Memorial Hospital
      • Milwaukee, Wisconsin, Forenede Stater, 53226
        • Froedtert and The Medical College of Wisconsin
      • Milwaukee, Wisconsin, Forenede Stater, 53209
        • Aurora Cancer Care-Milwaukee
      • Milwaukee, Wisconsin, Forenede Stater, 53215
        • Aurora Saint Luke's Medical Center
      • Milwaukee, Wisconsin, Forenede Stater, 53233
        • Aurora Sinai Medical Center
      • Minocqua, Wisconsin, Forenede Stater, 54548
        • Marshfield Clinic-Minocqua Center
      • Mukwonago, Wisconsin, Forenede Stater, 53149
        • ProHealth D N Greenwald Center
      • New Richmond, Wisconsin, Forenede Stater, 54017
        • Cancer Center of Western Wisconsin
      • Oconomowoc, Wisconsin, Forenede Stater, 53066
        • ProHealth Oconomowoc Memorial Hospital
      • Oconto Falls, Wisconsin, Forenede Stater, 54154
        • Green Bay Oncology - Oconto Falls
      • Oshkosh, Wisconsin, Forenede Stater, 54904
        • Vince Lombardi Cancer Clinic - Oshkosh
      • Racine, Wisconsin, Forenede Stater, 53406
        • Aurora Cancer Care-Racine
      • Rhinelander, Wisconsin, Forenede Stater, 54501
        • Ascension Saint Mary's Hospital
      • Rhinelander, Wisconsin, Forenede Stater, 54501
        • Saint Mary's Hospital
      • Rice Lake, Wisconsin, Forenede Stater, 54868
        • Lakeview Medical Center-Marshfield Clinic
      • Rice Lake, Wisconsin, Forenede Stater, 54868
        • Marshfield Clinic-Rice Lake Center
      • Sheboygan, Wisconsin, Forenede Stater, 53081
        • Vince Lombardi Cancer Clinic-Sheboygan
      • Sheboygan, Wisconsin, Forenede Stater, 53081
        • HSHS Saint Nicholas Hospital
      • Stevens Point, Wisconsin, Forenede Stater, 54482
        • Marshfield Clinic Stevens Point Center
      • Stevens Point, Wisconsin, Forenede Stater, 54481
        • Ascension Saint Michael's Hospital
      • Stevens Point, Wisconsin, Forenede Stater, 54481
        • Saint Michael's Hospital
      • Sturgeon Bay, Wisconsin, Forenede Stater, 54235-1495
        • Saint Vincent Hospital Cancer Center at Sturgeon Bay
      • Sturgeon Bay, Wisconsin, Forenede Stater, 54235
        • Green Bay Oncology - Sturgeon Bay
      • Summit, Wisconsin, Forenede Stater, 53066
        • Aurora Medical Center in Summit
      • Two Rivers, Wisconsin, Forenede Stater, 54241
        • Vince Lombardi Cancer Clinic-Two Rivers
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • UW Cancer Center at ProHealth Care
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • ProHealth Waukesha Memorial Hospital
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • Aurora Cancer Care-Waukesha
      • Wausau, Wisconsin, Forenede Stater, 54401
        • Aspirus Regional Cancer Center
      • Wausau, Wisconsin, Forenede Stater, 54401
        • Marshfield Clinic-Wausau Center
      • Wauwatosa, Wisconsin, Forenede Stater, 53226
        • Aurora Cancer Care-Milwaukee West
      • West Allis, Wisconsin, Forenede Stater, 53227
        • Aurora West Allis Medical Center
      • West Bend, Wisconsin, Forenede Stater, 53095
        • The Alyce and Elmore Kraemer Cancer Care Center
      • Weston, Wisconsin, Forenede Stater, 54476
        • Diagnostic and Treatment Center
      • Weston, Wisconsin, Forenede Stater, 54476
        • Marshfield Clinic - Weston Center
      • Weston, Wisconsin, Forenede Stater, 54476
        • Saint Clare's Hospital
      • Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
        • Marshfield Clinic - Wisconsin Rapids Center
      • Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
        • Aspirus UW Cancer Center
    • Wyoming
      • Casper, Wyoming, Forenede Stater, 82609
        • Rocky Mountain Oncology
      • Cody, Wyoming, Forenede Stater, 82414
        • Big Horn Basin Cancer Center
      • Cody, Wyoming, Forenede Stater, 82414
        • Billings Clinic-Cody
      • Sheridan, Wyoming, Forenede Stater, 82801
        • Welch Cancer Center

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Prøveudtagningsmetode

Sandsynlighedsprøve

Studiebefolkning

Patienter skal have patologisk dokumenteret pladecellekræft (SCCA) i lungen bekræftet ved tumorbiopsi og/eller finnålsaspiration; sygdom skal være fase IV SCCA eller tilbagevendende; den primære diagnose af SCCA bør etableres ved hjælp af den nuværende World Health Organization (WHO)/International Association for the Study of Lung Cancer (IASLC)-klassifikation af Thoracic Malignancies; diagnosen er baseret på hæmatoxylin og eosin (H&E)-farvede objektglas med eller uden specifik defineret immunhistokemi (IHC) karakteristik (p40/p63 positiv, transkriptionstermineringsfaktor [TTF1] negativ), hvis det er nødvendigt for diagnosen; blandede histologier er ikke tilladt

Beskrivelse

Inklusionskriterier:

  • SCREENING/FØR-SCREENING REGISTRERING:
  • Patienter skal have patologisk dokumenteret pladecellekræft (SCCA) i lungen bekræftet ved tumorbiopsi og/eller finnålsaspiration; sygdom skal være fase IV SCCA eller tilbagevendende; den primære diagnose af SCCA bør etableres ved hjælp af den nuværende World Health Organization (WHO)/International Association for the Study of Lung Cancer (IASLC)-klassifikation af Thoracic Malignancies; diagnosen er baseret på hæmatoxylin og eosin (H&E)-farvede objektglas med eller uden specifik defineret immunhistokemi (IHC) karakteristik (p40/p63 positiv, transkriptionstermineringsfaktor [TTF1] negativ), hvis det er nødvendigt for diagnosen; blandede histologier er ikke tilladt

  • Patienter skal enten være berettiget til at blive screenet ved progression på tidligere behandling eller til at blive forhåndsscreenet før progression på nuværende behandling; patienter vil enten give samtykke til screeningssamtykket eller forudgående screeningssamtykke, ikke begge dele; disse kriterier er:

    • Screening ved progression på tidligere behandling: For at være berettiget til screening ved progression skal patienter have modtaget mindst én linje af systemisk terapi for ethvert sygdomsstadie (stadier I-IV) og skal have udviklet sig under eller efter deres seneste behandlingslinje ; for patienter, hvis tidligere systemiske behandling kun var for sygdomsstadie I-III (dvs. patienten ikke har modtaget nogen behandling for stadium IV eller tilbagevendende sygdom), skal den tidligere systemiske behandling have været et platinbaseret kemoterapiregime, og sygdomsprogression på platinbaseret kemoterapi skal være sket inden for et år fra den sidste dato, hvor patienten modtog terapi; for patienter, hvis tidligere behandling var for stadium IV eller tilbagevendende sygdom, skal patienten have modtaget mindst én linje af et platinbaseret kemoterapiregime eller checkpoint-hæmmerbehandling (f. nivolumab eller pembrolizumab)
    • Præscreening forud for progression af den nuværende behandling: For at være berettiget til præscreening skal den aktuelle behandling være for stadium IV eller tilbagevendende sygdom, og patienten skal have modtaget mindst én dosis af det aktuelle regime; patienter skal tidligere have modtaget eller i øjeblikket modtager en platin-baseret kemoterapi eller checkpoint-hæmmerbehandling (f. nivolumab eller pembrolizumab); patienter i førstelinjes platin-baseret behandling er kvalificerede efter at have modtaget cyklus 1, dag 1 infusion; Bemærk: Patienter vil ikke modtage deres delstudieopgave, før de skrider frem, og S1400-meddelelsen om fremskridt er indsendt

  • Patienter skal have tilstrækkeligt tumorvæv til rådighed, defineret som >= 20 % tumorceller og >= 0,2 mm^3 tumorvolumen

    • Den lokale tolkepatolog skal gennemgå prøven
    • Patologen skal underskrive S1400 Local Pathology Review Form, der bekræfter vævstilstrækkelighed før screening/før-screening registrering
    • Patienter skal acceptere at få dette væv indsendt til Foundation Medicine til fælles bred platform Clinical Laboratory Improvement Act (CLIA) biomarkørprofilering; hvis arkivtumormateriale er udtømt, skal der opnås en ny frisk tumorbiopsi, der er formalinfikseret og paraffinindlejret (FFPE); en tumorblok eller FFPE-objektglas med en tykkelse på 4-5 mikrometer skal indsendes; knoglebiopsier er ikke tilladt; hvis der skal indsendes FFPE-objektglas, skal der indsendes mindst 12 ufarvede objektglas plus et H&E-farvet objektglas, eller 13 ufarvede objektglas; det anbefales dog kraftigt, at der indsendes 20 FFPE-objektglas; Bemærk: forrige næste generation af deoxyribonukleinsyre (DNA) sekventering (NGS) vil blive gentaget, hvis det udføres uden for denne undersøgelse til sub-studie opgave; Patienter skal acceptere at have ethvert væv, der er tilbage efter NGS-test, bevaret til brug af translationel medicin (TM)-undersøgelser (hvis sådanne TM-undersøgelser er defineret) inden for ethvert delstudie, som patienten er indskrevet i
  • Patienter må ikke have en kendt epidermal vækstfaktor receptor (EGFR) mutation eller anaplastisk lymfom kinase (ALK) fusion; EGFR/ALK-test er ikke påkrævet før registrering og er inkluderet i Foundation Medicine Incorporated (FMI) test til screening/præscreening
  • Patienter skal have Zubrod præstationsstatus 0-1 dokumenteret inden for 28 dage før screening/før-screeningsregistrering
  • Patienter skal også tilbydes deltagelse i bankvirksomhed til fremtidig brug af prøver
  • Patienter skal være villige til at angive tidligere rygehistorie som krævet på S1400 Onstudy Form
  • Som en del af registreringsprocessen for Oncology Patient Enrollment Network (OPEN) oplyses den behandlende institutions identitet for at sikre, at den aktuelle (inden for 365 dage) dato for institutionsbedømmelsesudvalgets godkendelse af denne undersøgelse er blevet indtastet i systemet
  • Patienterne skal informeres om undersøgelsens karakter af denne undersøgelse og skal underskrive og give skriftligt informeret samtykke i overensstemmelse med institutionelle og føderale retningslinjer
  • TILMELDING AF DELSTUDIE:
  • Patienter, hvis biomarkørprofileringsresultater indikerer tilstedeværelsen af ​​en EGFR-mutation eller pighudermikrotubuli-associeret protein-lignende 4 (EML4)/ALK-fusion, er ikke kvalificerede
  • Patienterne skal have udviklet sig (efter den behandlende investigators mening) efter den seneste behandlingslinje
  • Patienter må ikke have modtaget nogen tidligere systemisk terapi (systemisk kemoterapi, immunterapi eller forsøgslægemiddel) inden for 21 dage før registrering af delstudiet; patienter skal være kommet sig (=< grad 1) fra eventuelle bivirkninger fra tidligere behandling; patienter må ikke have modtaget strålebehandling inden for 14 dage før delstudieregistrering
  • Patienter skal have målbar sygdom dokumenteret ved computertomografi (CT) eller magnetisk resonansbilleddannelse (MRI); CT'en fra en kombineret positronemissionstomografi (PET)/CT kan kun bruges til at dokumentere ikke-målbar sygdom, medmindre den er af diagnostisk kvalitet; målbar sygdom skal vurderes inden for 28 dage før delstudieregistrering; pleurale effusioner, ascites og laboratorieparametre er ikke acceptable som det eneste tegn på sygdom; ikke-målbar sygdom skal vurderes inden for 42 dage før registrering af delstudiet; al sygdom skal vurderes og dokumenteres på Baseline Tumor Assessment Form; patienter, hvis eneste målbare sygdom er inden for en tidligere stråleterapiport, skal demonstrere klart fremadskridende sygdom (efter den behandlende investigators mening) før registrering
  • Patienter skal have en CT- eller MR-scanning af hjernen for at evaluere for sygdom i centralnervesystemet (CNS) inden for 42 dage før registrering af delstudiet; patienten må ikke have leptomeningeal sygdom, rygmarvskompression eller hjernemetastaser, medmindre: (1) metastaser er blevet lokalt behandlet og er forblevet klinisk kontrollerede og asymptomatiske i mindst 14 dage efter behandling og før registrering, OG (2) patienten ikke har nogen resterende neurologisk dysfunktion og har været ude af kortikosteroider i mindst 24 timer før delstudieregistrering
  • Patienten skal være fuldstændig restitueret efter virkningerne af tidligere operation mindst 14 dage før registrering af delstudiet
  • Patienter må ikke planlægge at modtage samtidig kemoterapi, immunterapi, biologisk eller hormonbehandling til cancerbehandling; Samtidig brug af hormoner til ikke-kræftrelaterede tilstande (f.eks. insulin til diabetes og hormonsubstitutionsterapi) er acceptabel
  • Absolut neutrofiltal (ANC) >= 1.500/mcl opnået inden for 28 dage før registrering af delstudie
  • Blodpladetal >= 100.000 mcl opnået inden for 28 dage før registrering af delstudie
  • Hæmoglobin >= 9 g/dL opnået inden for 28 dage før registrering af delstudiet
  • Serumbilirubin =< institutionel øvre normalgrænse (IULN) inden for 28 dage før registrering af delstudiet; for patienter med levermetastaser skal bilirubin være =< 5 x IULN
  • Enten alaninaminotransferase (ALAT) eller aspartataminotransferase (AST) =< 2 x IULN inden for 28 dage før registrering af delstudiet (hvis både ALT og ASAT udføres, skal begge være =< 2 IULN); for patienter med levermetastaser skal enten ALAT eller ASAT være =< 5 x IULN (hvis både ALAT og ASAT udføres, skal begge være =< 5 x IULN)
  • Serumkreatinin =< IULN ELLER målt eller beregnet kreatininclearance >= 50 ml/min ved brug af følgende Cockcroft-Gault-formel inden for 28 dage før registrering af delstudiet
  • Patienter skal have Zubrod præstationsstatus 0-1 dokumenteret inden for 28 dage før registrering af delstudiet
  • Patienter må ikke have nogen grad III/IV hjertesygdom som defineret af New York Heart Association Criteria (dvs. patienter med hjertesygdom, der resulterer i markant begrænsning af fysisk aktivitet eller resulterer i manglende evne til at udføre fysisk aktivitet uden ubehag), ustabil angina pectoris og myokardieinfarkt inden for 6 måneder eller alvorlig ukontrolleret hjertearytmi
  • Patienter må ikke have dokumenteret tegn på akut hepatitis eller have en aktiv eller ukontrolleret infektion

  • Patienter med en kendt historie med human immundefektvirus (HIV) seropositivitet:

    • Skal have upåviselig viral belastning ved brug af standard HIV-assays i klinisk praksis
    • Skal have cluster of differentiation (CD)4 count >= 400/mcL
    • Må ikke kræve profylakse for nogen opportunistiske infektioner (dvs. svampe-, Mycobacterium avium-kompleks [mAC] eller pneumocystis jiroveci pneumoni [PCP]-profylakse)
    • Må ikke være nydiagnosticeret inden for 12 måneder før delstudieregistrering
  • Forstudiehistorie og fysisk eksamen skal indhentes inden for 28 dage før delstudieregistrering
  • Ingen anden tidligere malignitet er tilladt bortset fra følgende: tilstrækkeligt behandlet basalcelle- eller pladecellehudkræft, in situ livmoderhalskræft, tilstrækkeligt behandlet stadium I- eller II-kræft, hvorfra patienten i øjeblikket er i fuldstændig remission, eller enhver anden kræftsygdom, hvorfra patienten har været sygdomsfri i fem år
  • Patienter må ikke være gravide eller ammende; kvinder/mænd med reproduktionspotentiale skal have accepteret at bruge en effektiv præventionsmetode; en kvinde anses for at have "reproduktionspotentiale", hvis hun har haft menstruation på noget tidspunkt i de foregående 12 på hinanden følgende måneder; ud over rutinepræventionsmetoder omfatter "effektiv prævention" også heteroseksuel cølibat og kirurgi beregnet til at forhindre graviditet (eller med en bivirkning af graviditetsforebyggelse) defineret som en hysterektomi, bilateral ooforektomi eller bilateral tubal ligering; men hvis en tidligere cølibatpatient på noget tidspunkt vælger at blive heteroseksuelt aktiv i løbet af tidsperioden for brug af præventionsforanstaltninger, der er beskrevet i protokollen, er han/hun ansvarlig for at påbegynde præventionsforanstaltninger
  • Som en del af OPEN registreringsprocessen er den behandlende institution identitet er angivet for at sikre, at den aktuelle (inden for 365 dage) dato for institutionelle bedømmelsesudvalgs godkendelse af denne undersøgelse er blevet indtastet i systemet
  • Patienter med nedsat beslutningsevne er kvalificerede, så længe deres neurologiske eller psykologiske tilstand ikke udelukker deres sikre deltagelse i undersøgelsen (f.eks. sporing af pilleforbrug og rapportering af uønskede hændelser til investigator)
  • Patienterne skal informeres om undersøgelsens karakter af denne undersøgelse og skal underskrive og give skriftligt informeret samtykke i overensstemmelse med institutionelle og føderale retningslinjer.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Kohorter og interventioner

Gruppe / kohorte
Intervention / Behandling
S1400A Arm I (MEDI4736) (LUKKET FOR OPDATERING 12/2015)
Patienter med tumorer, der ikke matcher en af ​​de aktuelt aktive lægemiddel-biomarkørkombinationer randomiseret til Arm I, modtager anti-B7H1 monoklonalt antistof MEDI4736 IV over 60 minutter på dag 1. Behandlingen gentages hver 14. dag i 12 måneder i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Biologisk: Durvalumab
Givet IV
Andre navne:
  • Imfinzi
  • Immunoglobulin G1, Anti-(Humant Protein B7-H1) (Human Monoklonal MEDI4736 Heavy Chain), Disulfid med Human Monoklonal MEDI4736 Kappa-kæde, Dimer
  • MEDI-4736
  • MEDI4736
S1400A Arm II (LUKKET FOR OPDATERING 4/2015)
Patienter med tumorer, der ikke matcher en af ​​de aktuelt aktive lægemiddel-biomarkør kombinationer randomiseret til arm II, modtager docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #2 22/4/15)
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Docetaxel
Givet IV
Andre navne:
  • Taxotere
  • Docecad
  • RP56976
  • Taxotere injektionskoncentrat
S1400A Arm III (MEDI4736)
For patienter tilknyttet arm 1, MEDI4736: Ved tegn på progression efter seponering af 12 måneders behandling, kan patienter genoptage behandlingen med arm 3, MEDI4736 i op til 12 måneder med de samme behandlingsretningslinjer som følges i den indledende 12-måneders behandlingsperiode. Patienter vil kun kunne genoptage behandlingen én gang; således vil der højst være tilladt to 12-måneders perioder. Patienter registreret i arm III får durvalumab IV over 60 minutter på dag 1. Behandlingen gentages hver 14. dag i 12 måneder i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Biologisk: Durvalumab
Givet IV
Andre navne:
  • Imfinzi
  • Immunoglobulin G1, Anti-(Humant Protein B7-H1) (Human Monoklonal MEDI4736 Heavy Chain), Disulfid med Human Monoklonal MEDI4736 Kappa-kæde, Dimer
  • MEDI-4736
  • MEDI4736
S1400B Arm I (taselisib) (LUKKET FOR OPDATERING 12/12/2016)
Patienter med tumorer positive for PI3KCA randomiseret til arm I modtager taselisib PO dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Taselisib
Givet PO
Andre navne:
  • GDC-0032
S1400B Arm II (LUKKET FOR OPDATERING 18.12.2015)
Patienter med tumorer positive for PI3KCA randomiseret til arm II modtager docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #3 18/12/2015)
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Docetaxel
Givet IV
Andre navne:
  • Taxotere
  • Docecad
  • RP56976
  • Taxotere injektionskoncentrat
S1400B Arm III (taselisib) (LUKKET FOR OPDATERING 12/12/2016)
Genregistreringsbehandling med GDC-0032 (Taselisib). Efter progression kan patienter i arm 2 være berettiget til genregistrering for at modtage GDC-0032. Patienterne vil modtage taselisib PO dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Taselisib
Givet PO
Andre navne:
  • GDC-0032
S1400C Arm I (palbociclib)
Patienter med tumorer positive for CDK4/6, CCND1, CCND2 og CCND3 randomiseret til arm I modtager palbociclib PO på dag 1-21. Kurser gentages hver 28. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Palbociclib
Givet PO
Andre navne:
  • Ibrance
  • PD-0332991
  • PD-332991
S1400C Arm II (LUKKET FOR OPDATERING 18/12/2015)
Patienter med tumorer positive for CDK4, CCND1, CCND2 og CCND3 randomiseret til Arm II modtager docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #3 18/12/2015)
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Docetaxel
Givet IV
Andre navne:
  • Taxotere
  • Docecad
  • RP56976
  • Taxotere injektionskoncentrat
S1400C Arm III (palbociclib)
Genregistrering Behandling med palbociclib. Efter progression kan patienter i arm 2 være berettiget til genregistrering for at modtage palbociclib. Patienterne vil modtage palbociclib PO på dag 1-21. Kurser gentages hver 28. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Palbociclib
Givet PO
Andre navne:
  • Ibrance
  • PD-0332991
  • PD-332991
S1400D Arm I (AZD4547) (LUKKET FOR OPDATERING 04/12/2017)
Patienter med tumorer positive for FGFR1, FGFR2 og FGFR3 randomiseret til arm I modtager FGFR-hæmmer AZD4547 PO BID på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: FGFR-hæmmer AZD4547
Givet PO
Andre navne:
  • AZD4547
S1400D Arm II (LUKKET FOR OPDATERING 31/10/2016)
Patienter med tumorer positive for FGFR1, FGFR2 og FGFR3 randomiseret til Arm II modtager docetaxel IV på dag 1. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (lukket for periodisering med revision #3 18/12/2015)
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Docetaxel
Givet IV
Andre navne:
  • Taxotere
  • Docecad
  • RP56976
  • Taxotere injektionskoncentrat
S1400D Arm III (AZD4547) (LUKKET FOR OPDATERING 31/10/2016)
Genregistreringsbehandling med AZD4547. Efter progression kan patienter i arm 2 være berettiget til genregistrering for at modtage AZD4547. Patienter vil modtage FGFR-hæmmer AZD4547 PO BID på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: FGFR-hæmmer AZD4547
Givet PO
Andre navne:
  • AZD4547
S1400E Arm I (LUKKET FOR OPDATERING 11/2014)
Patienter med tumorer positive for HGF/c-MET randomiseret til arm I modtager rilotumumab IV på dag 1 og erlotinib hydrochlorid PO dagligt. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (permanent lukket for optjening den 25/11/14)
Medicin: Erlotinib hydrochlorid
Givet PO
Andre navne:
  • Cp-358.774
  • Tarceva
  • OSI-774
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Biologisk: Rilotumumab
Givet IV
Andre navne:
  • AMG 102
  • Anti-HGF monoklonalt antistof AMG 102
  • Fuldt humant anti-HGF monoklonalt antistof AMG 102
S1400E Arm II (LUKKET FOR OPDATERING 11/2014)
Patienter med tumorer positive for HGF/c-MET randomiseret til arm II modtager erlotinib hydrochlorid PO dagligt. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet. (permanent lukket for optjening den 25/11/14)
Medicin: Erlotinib hydrochlorid
Givet PO
Andre navne:
  • Cp-358.774
  • Tarceva
  • OSI-774
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
S1400F (durvalumab, tremelimumab)
Patienter med sygdomsprogression under eller efter tidligere anti-PD-1 eller anti-PD-L1 antistof monoterapi som deres seneste behandlingslinje får durvalumab (IV over 60 minutter) og tremelimumab (IV over 60 minutter) på dag 1 for forløb 1 -4 og durvalumab IV alene på dag 1 af kursus 5 og efterfølgende forløb indtil sygdomsprogression eller uacceptabel toksicitet. Kurser gentages hver 28. dag.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Andet: Farmakologisk undersøgelse
Korrelative undersøgelser
Biologisk: Durvalumab
Givet IV
Andre navne:
  • Imfinzi
  • Immunoglobulin G1, Anti-(Humant Protein B7-H1) (Human Monoklonal MEDI4736 Heavy Chain), Disulfid med Human Monoklonal MEDI4736 Kappa-kæde, Dimer
  • MEDI-4736
  • MEDI4736
Biologisk: Tremelimumab
Givet IV
Andre navne:
  • Anti-CTLA4 humant monoklonalt antistof CP-675.206
  • CP-675
  • CP-675.206
  • CP-675206
  • ticilimumab
S1400G (talazoparib)
Patienter med tumorer, der er positive for homolog rekombinationsreparationsmangel, modtager talazoparib PO dagligt på dag 1-21. Kurser gentages hver 21. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Andet: Farmakologisk undersøgelse
Korrelative undersøgelser
Medicin: Talazoparib
Givet PO
Andre navne:
  • BMN 673
  • BMN-673
S1400I Arm I (nivolumab, ipilimumab)
Patienter med tumorer, der ikke matcher en af ​​de aktuelt aktive lægemiddel-biomarkør-kombinationer eller ikke opfyldte berettigelseskravene til det biomarkørdrevne delstudie randomiseret til arm I modtager nivolumab IV over 30 minutter på dag 1 og ipilimumab IV over 60 minutter på dag 1 i hver tredje cyklus. Kurser gentages hver 14. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Biologisk: Nivolumab
Givet IV
Andre navne:
  • BMS-936558
  • MDX-1106
  • NIVO
  • ONO-4538
  • Opdivo
Biologisk: Ipilimumab
Givet IV
Andre navne:
  • Anti-cytotoksisk T-lymfocyt-associeret antigen-4 monoklonalt antistof
  • BMS-734016
  • MDX-010
  • MDX-CTLA4
  • Yervoy
S1400I Arm II (nivolumab)
Patienter med tumorer, der ikke matcher en af ​​de aktuelt aktive lægemiddel-biomarkør-kombinationer eller ikke opfyldte berettigelseskravene til det biomarkørdrevne delstudie randomiseret til arm II, modtager nivolumab IV over 30 minutter på dag 1. Kurser gentages hver 14. dag i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Biologisk: Nivolumab
Givet IV
Andre navne:
  • BMS-936558
  • MDX-1106
  • NIVO
  • ONO-4538
  • Opdivo
Andet: Farmakologisk undersøgelse
Korrelative undersøgelser

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Skærmens succesrate
Tidsramme: Fra registreringsdato til præ-screening eller screeningskomponent indtil delstudieregistrering eller død, en median på 3,5 måneder (IQR 2,0-6,0) i den præ-screenede gruppe og 0,9 måneder (IQR 0,7-1,1) i den screenede ved progression gruppe.

Procentdel af deltagere, der tilmeldte sig et terapeutisk delstudie ud af dem, der modtog en delstudieopgave.

For at modtage en delstudieopgave skal tilmeldte deltagere have indsendt væv, haft biomarkørresultater og været matchet til et terapeutisk delstudie.
Fra registreringsdato til præ-screening eller screeningskomponent indtil delstudieregistrering eller død, en median på 3,5 måneder (IQR 2,0-6,0) i den præ-screenede gruppe og 0,9 måneder (IQR 0,7-1,1) i den screenede ved progression gruppe.

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

SWOG Cancer Research Network

Samarbejdspartnere

National Cancer Institute (NCI)

Efterforskere

  • Ledende efterforsker: Vassiliki Papadimitrakopoulou, SWOG Cancer Research Network

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

8. juli 2014

Primær færdiggørelse (Faktiske)

1. april 2022

Studieafslutning (Faktiske)

15. april 2022

Datoer for studieregistrering

Først indsendt

30. maj 2014

Først indsendt, der opfyldte QC-kriterier

2. juni 2014

Først opslået (Anslået)

3. juni 2014

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

1. juni 2023

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

30. maj 2023

Sidst verificeret

1. maj 2023

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • S1400 (Anden identifikator: CTEP)
  • U10CA180888 (U.S. NIH-bevilling/kontrakt)
  • S1400C (CTEP)
  • S1400I (CTEP)
  • S1400E (CTEP)
  • S1400D (CTEP)
  • NCI-2014-00627 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
  • S1400A (CTEP)
  • S1400B

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Ingen

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ja

produkt fremstillet i og eksporteret fra U.S.A.

Ja

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

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Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Macedonia

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer

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