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Doxorubicin hydrochlorid og cyclophosphamid efterfulgt af paclitaxel med eller uden carboplatin til behandling af patienter med triple-negativ brystkræft

5. maj 2026 opdateret af: NRG Oncology

Et randomiseret fase III-forsøg med adjuverende terapi, der sammenligner doxorubicin plus cyclophosphamid efterfulgt af ugentlig paclitaxel med eller uden carboplatin for knudepositiv eller højrisikoknude-negativ triple-negativ invasiv brystkræft

Dette randomiserede fase III-studie undersøger, hvor godt doxorubicinhydrochlorid og cyclophosphamid efterfulgt af paclitaxel med eller uden carboplatin virker ved behandling af patienter med triple-negativ brystkræft. Lægemidler, der bruges i kemoterapi, såsom doxorubicinhydrochlorid, cyclophosphamid, paclitaxel og carboplatin, virker på forskellige måder for at stoppe væksten af ​​tumorceller, enten ved at dræbe cellerne, ved at stoppe dem i at dele sig eller ved at stoppe dem i at sprede sig. Det vides endnu ikke, om doxorubicinhydrochlorid og cyclophosphamid er mere effektive, når de efterfølges af paclitaxel alene eller paclitaxel og carboplatin til behandling af triple-negativ brystkræft.

Studieoversigt

Status

Aktiv, ikke rekrutterende

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

PRIMÆRE MÅL:

I. At bestemme, om tilføjelsen af ​​carboplatin til et adjuverende kemoterapiregime af doxorubicin (doxorubicinhydrochlorid)/cyclophosphamid efterfulgt af paclitaxel vil forbedre den invasive sygdomsfrie overlevelse (IDFS) sammenlignet med doxorubicin/cyclophosphamid efterfulgt af paclitaxel, når det administreres til patienter node-positiv eller højrisiko node-negativ triple-negativ brystkræft.

SEKUNDÆRE MÅL:

I. For at bestemme, om tilføjelsen af ​​carboplatin til et adjuverende kemoterapiregime af doxorubicin/cyclophosphamid efterfulgt af paclitaxel vil forbedre den samlede overlevelse (OS) sammenlignet med doxorubicin/cyclophosphamid efterfulgt af paclitaxel, når det administreres til patienter med operable node-positive eller høj-risiko node-negativ trippel-negativ brystkræft.

II. For at bestemme, om tilføjelsen af ​​carboplatin til et adjuverende kemoterapiregime af doxorubicin/cyclophosphamid efterfulgt af paclitaxel vil forbedre brystkræftfri overlevelse (BCFS) sammenlignet med doxorubicin/cyclophosphamid efterfulgt af paclitaxel, når det administreres til patienter med operable node-positive eller høj- risiko node-negativ triple-negativ brystkræft.

III. For at bestemme, om tilføjelsen af ​​carboplatin til et adjuverende kemoterapiregime af doxorubicin/cyclophosphamid efterfulgt af paclitaxel vil forbedre det gentagelsesfrie interval (RFI) sammenlignet med doxorubicin/cyclophosphamid efterfulgt af paclitaxel, når det administreres til patienter med operable node-positive eller høj-risiko node-negativ trippel-negativ brystkræft.

IV. For at afgøre, om tilføjelsen af ​​carboplatin til et adjuverende kemoterapiregime af doxorubicin/cyclophosphamid efterfulgt af paclitaxel vil forbedre det fjerne gentagelsesfrie interval (DRFI) sammenlignet med doxorubicin/cyclophosphamid efterfulgt af paclitaxel, når det administreres til patienter med operable nodepositive eller høje nodepositive. risiko node-negativ triple-negativ brystkræft.

V. At bestemme toksiciteten af ​​doxorubicin/cyclophosphamid efterfulgt af paclitaxel indgivet samtidig med carboplatin sammenlignet med toksiciteten af ​​doxorubicin/cyclophosphamid efterfulgt af paclitaxel alene.

VI. For at bestemme, om kimlinjebrystkræftstatus (BRCA) er forbundet med fordel ved IDFS eller OS fra tilføjelse af carboplatin til et adjuverende kemoterapiregime med doxorubicin/cyclophosphamid efterfulgt af paclitaxel hos patienter med operabel node-positiv eller højrisiko node-negativ triple -negativ brystkræft.

VII. For at bestemme, om tilsætning af carboplatin vil forbedre RFI blandt de homologe rekombinations (HR) deficiente patienter som bestemt af homolog rekombinations mangel (HRD) score.

VIII. At bestemme, om effekten af ​​carboplatin på RFI hos patienter med HR-mangel adskiller sig fra den hos patienter, der ikke er HR-mangelfulde.

IX. At indsamle vævs- og blodprøver ved flere lejligheder til fremtidig udvikling af biomarkører til at forudsige risikoen for tilbagefald af brystkræft hos patienter med operabel node-positiv eller højrisiko-knude-negativ tripel-negativ brystkræft behandlet med doxorubicin/cyclophosphamid efterfulgt af paclitaxel med eller uden carboplatin og forudsige fordele ved tilsætning af carboplatin blandt disse patienter.

OVERSIGT: Patienterne randomiseres til 1 ud af 2 behandlingsarme.

ARM I (DOXORUBICIN HYDROCHLORID [A] CYCLOPHOSPHAMID [C]-->UGENTLIG PACLITAXEL [WP]): Patienter får doxorubicin hydrochlorid intravenøst ​​(IV) over 15 minutter og cyclophosphamid IV over 30 minutter på dag 1. Behandlingen gentages hver 2. uge i 4 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienterne får derefter paclitaxel IV over 60 minutter på dag 1. Behandlingen gentages ugentligt i 12 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet.

ARM II (AC-->WP + CARBOPLATIN): Patienterne får doxorubicinhydrochlorid og cyclophosphamid som i arm I. Patienterne får derefter paclitaxel IV over 60 minutter på dag 1, 8 og 15 og carboplatin IV over 30-60 minutter på dag 1 . Behandlingen gentages hver 3. uge i 4 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet.

Efter afsluttet undersøgelsesbehandling følges patienterne hver 6. måned i 5 år og derefter hver 12. måned i 5 år.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

782

Fase

  • Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

  • Canada
    • Alberta
      • Calgary, Alberta, Canada, T2N 4N2
        • Tom Baker Cancer Centre
    • Ontario
      • Greater Sudbury, Ontario, Canada, P3E 5J1
        • Health Sciences North
    • Quebec
      • Montreal, Quebec, Canada, H3T 1E2
        • Jewish General Hospital
      • Montreal, Quebec, Canada, H3H 2R9
        • The Research Institute of the McGill University Health Centre (MUHC)
      • Montreal, Quebec, Canada, H2L 4M1
        • CHUM - Hopital Notre-Dame
      • Montreal, Quebec, Canada, H2W 1S6
        • McGill University Department of Oncology
      • Montreal, Quebec, Canada, H2W 1T8
        • CHUM-Hotel Dieu de Montreal
      • Montreal, Quebec, Canada, H2X 3E4
        • CHUM - Centre Hospitalier de l'Universite de Montreal
      • Sherbrooke, Quebec, Canada, J1H 5N4
        • Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
    • Saskatchewan
      • Regina, Saskatchewan, Canada, S4T 7T1
        • Allan Blair Cancer Centre
  • Forenede Stater
    • Alabama
      • Mobile, Alabama, Forenede Stater, 36607
        • Southern Cancer Center PC-Mobile
      • Mobile, Alabama, Forenede Stater, 36608
        • Southern Cancer Center PC-Providence
      • Mobile, Alabama, Forenede Stater, 36608
        • Southern Cancer Center PC-Springhill
    • Alaska
      • Anchorage, Alaska, Forenede Stater, 98508
        • Anchorage Associates in Radiation Medicine
      • Anchorage, Alaska, Forenede Stater, 99508
        • Alaska Breast Care and Surgery LLC
      • Anchorage, Alaska, Forenede Stater, 99508
        • Alaska Oncology and Hematology LLC
      • Anchorage, Alaska, Forenede Stater, 99508
        • Alaska Women's Cancer Care
      • Anchorage, Alaska, Forenede Stater, 99508
        • Anchorage Oncology Centre
      • Anchorage, Alaska, Forenede Stater, 99508
        • Katmai Oncology Group
      • Anchorage, Alaska, Forenede Stater, 99508
        • Providence Alaska Medical Center
      • Anchorage, Alaska, Forenede Stater, 99504
        • Anchorage Radiation Therapy Center
      • Anchorage, Alaska, Forenede Stater, 99508
        • Alaska Regional Hospital
      • Fairbanks, Alaska, Forenede Stater, 99701
        • Fairbanks Memorial Hospital
    • Arizona
      • Gilbert, Arizona, Forenede Stater, 85297
        • Arizona Breast Cancer Specialists-Gilbert
      • Glendale, Arizona, Forenede Stater, 85306
        • Virginia G Piper Cancer Care-Glendale
      • Goodyear, Arizona, Forenede Stater, 85338
        • CTCA at Western Regional Medical Center
      • Peoria, Arizona, Forenede Stater, 85381
        • Arizona Center for Cancer Care-Peoria
      • Phoenix, Arizona, Forenede Stater, 85027
        • Arizona Oncology-Deer Valley Center
      • Phoenix, Arizona, Forenede Stater, 85016
        • Arizona Oncology Associates-Biltmore Cancer Center
      • Phoenix, Arizona, Forenede Stater, 85027
        • Arizona Breast Cancer Specialists-Phoenix
      • Scottsdale, Arizona, Forenede Stater, 85258
        • Arizona Breast Cancer Specialists-Scottsdale
      • Scottsdale, Arizona, Forenede Stater, 85251
        • Arizona Breast Cancer Specialists
      • Scottsdale, Arizona, Forenede Stater, 85258
        • Virginia G Piper Cancer Care-Del Camino
      • Scottsdale, Arizona, Forenede Stater, 85258
        • Oncogyne PC-Arizona Oncology
      • Sedona, Arizona, Forenede Stater, 86336
        • Sedona Medical Center
      • Surprise, Arizona, Forenede Stater, 85374
        • Arizona Center for Cancer Care-Surprise
    • Arkansas
      • Fort Smith, Arkansas, Forenede Stater, 72903
        • Mercy Hospital Fort Smith
      • Hot Springs, Arkansas, Forenede Stater, 71913
        • CHI Saint Vincent Cancer Center Hot Springs
      • Jonesboro, Arkansas, Forenede Stater, 72401
        • Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
      • Little Rock, Arkansas, Forenede Stater, 72205
        • University of Arkansas for Medical Sciences
    • California
      • Anaheim, California, Forenede Stater, 92806
        • Kaiser Permanente-Anaheim
      • Antioch, California, Forenede Stater, 94531
        • Kaiser Permanente-Deer Valley Medical Center
      • Arroyo Grande, California, Forenede Stater, 93420
        • PCR Oncology
      • Auburn, California, Forenede Stater, 95602
        • Sutter Auburn Faith Hospital
      • Auburn, California, Forenede Stater, 95603
        • Sutter Cancer Centers Radiation Oncology Services-Auburn
      • Bakersfield, California, Forenede Stater, 93301
        • AIS Cancer Center at San Joaquin Community Hospital
      • Baldwin Park, California, Forenede Stater, 91706
        • Kaiser Permanente-Baldwin Park
      • Bellflower, California, Forenede Stater, 90706
        • Kaiser Permanente-Bellflower
      • Berkeley, California, Forenede Stater, 94704
        • Alta Bates Summit Medical Center-Herrick Campus
      • Burbank, California, Forenede Stater, 91505
        • Providence Saint Joseph Medical Center/Disney Family Cancer Center
      • Burlingame, California, Forenede Stater, 94010
        • Mills-Peninsula Medical Center
      • Cameron Park, California, Forenede Stater, 95682
        • Sutter Cancer Centers Radiation Oncology Services-Cameron Park
      • Carmichael, California, Forenede Stater, 95608
        • Mercy San Juan Medical Center
      • Castro Valley, California, Forenede Stater, 94546
        • Eden Hospital Medical Center
      • Chico, California, Forenede Stater, 95973
        • Adventist Health Cancer Care Center Chico
      • Chico, California, Forenede Stater, 95926
        • Enloe Medical Center
      • Clovis, California, Forenede Stater, 93611
        • Community Cancer Institute
      • Clovis, California, Forenede Stater, 93611
        • University Oncology Associates
      • Davis, California, Forenede Stater, 95616
        • Sutter Davis Hospital
      • Dublin, California, Forenede Stater, 94568
        • Epic Care-Dublin
      • Emeryville, California, Forenede Stater, 94608
        • Bay Area Breast Surgeons Inc
      • Emeryville, California, Forenede Stater, 94608
        • Epic Care Partners in Cancer Care
      • Fontana, California, Forenede Stater, 92335
        • Kaiser Permanente-Fontana
      • Fremont, California, Forenede Stater, 94538
        • Kaiser Permanente-Fremont
      • Fresno, California, Forenede Stater, 93720
        • Kaiser Permanente-Fresno
      • Fullerton, California, Forenede Stater, 92835
        • Saint Jude Medical Center
      • Greenbrae, California, Forenede Stater, 94904
        • Marin Cancer Care Inc
      • Greenbrae, California, Forenede Stater, 94904
        • Marin General Hospital
      • Harbor City, California, Forenede Stater, 90710
        • Kaiser Permanente - Harbor City
      • Irvine, California, Forenede Stater, 92618
        • Kaiser Permanente-Irvine
      • La Jolla, California, Forenede Stater, 92093
        • UC San Diego Moores Cancer Center
      • Los Angeles, California, Forenede Stater, 90033
        • USC / Norris Comprehensive Cancer Center
      • Los Angeles, California, Forenede Stater, 90033
        • Los Angeles County-USC Medical Center
      • Los Angeles, California, Forenede Stater, 90027
        • Kaiser Permanente Los Angeles Medical Center
      • Los Angeles, California, Forenede Stater, 90034
        • Kaiser Permanente-Cadillac
      • Martinez, California, Forenede Stater, 94553-3156
        • Contra Costa Regional Medical Center
      • Marysville, California, Forenede Stater, 95901
        • Fremont - Rideout Cancer Center
      • Modesto, California, Forenede Stater, 95355
        • Memorial Medical Center
      • Modesto, California, Forenede Stater, 95356
        • Kaiser Permanente-Modesto
      • Mountain View, California, Forenede Stater, 94040
        • Palo Alto Medical Foundation-Camino Division
      • Mountain View, California, Forenede Stater, 94040
        • Palo Alto Medical Foundation-Gynecologic Oncology
      • Newport Beach, California, Forenede Stater, 92663
        • USC Norris Oncology/Hematology-Newport Beach
      • Novato, California, Forenede Stater, 94945
        • Sutter Cancer Research Consortium
      • Oakland, California, Forenede Stater, 94611
        • Kaiser Permanente-Oakland
      • Oakland, California, Forenede Stater, 94609
        • Alta Bates Summit Medical Center - Summit Campus
      • Oakland, California, Forenede Stater, 94609
        • Bay Area Tumor Institute
      • Palm Springs, California, Forenede Stater, 92262
        • Desert Regional Medical Center
      • Palo Alto, California, Forenede Stater, 94304
        • Stanford Cancer Institute Palo Alto
      • Palo Alto, California, Forenede Stater, 94301
        • Palo Alto Medical Foundation Health Care
      • Panorama City, California, Forenede Stater, 91402
        • Kaiser Permanente - Panorama City
      • Pasadena, California, Forenede Stater, 91105
        • Keck Medical Center of USC Pasadena
      • Pomona, California, Forenede Stater, 91767
        • Pomona Valley Hospital Medical Center
      • Rancho Mirage, California, Forenede Stater, 92270
        • Eisenhower Medical Center
      • Redwood City, California, Forenede Stater, 94063
        • Kaiser Permanente-Redwood City
      • Richmond, California, Forenede Stater, 94801
        • Kaiser Permanente-Richmond
      • Riverside, California, Forenede Stater, 92505
        • Kaiser Permanente-Riverside
      • Roseville, California, Forenede Stater, 95661
        • Kaiser Permanente-Roseville
      • Roseville, California, Forenede Stater, 95661
        • Sutter Cancer Centers Radiation Oncology Services-Roseville
      • Roseville, California, Forenede Stater, 95661
        • Sutter Roseville Medical Center
      • Sacramento, California, Forenede Stater, 95816
        • Sutter Medical Center Sacramento
      • Sacramento, California, Forenede Stater, 95817
        • University of California Davis Comprehensive Cancer Center
      • Sacramento, California, Forenede Stater, 95814
        • Kaiser Permanente Downtown Commons
      • Sacramento, California, Forenede Stater, 95823
        • Kaiser Permanente-South Sacramento
      • Sacramento, California, Forenede Stater, 95825
        • Kaiser Permanente - Sacramento
      • Sacramento, California, Forenede Stater, 95816
        • Mercy Cancer Center - Sacramento
      • Salinas, California, Forenede Stater, 93901
        • Salinas Valley Memorial
      • San Diego, California, Forenede Stater, 92120
        • Kaiser Permanente-San Diego Zion
      • San Diego, California, Forenede Stater, 92134
        • Naval Medical Center -San Diego
      • San Diego, California, Forenede Stater, 92108
        • Kaiser Permanente-San Diego Mission
      • San Francisco, California, Forenede Stater, 94115
        • Kaiser Permanente-San Francisco
      • San Francisco, California, Forenede Stater, 94115
        • California Pacific Medical Center-Pacific Campus
      • San Jose, California, Forenede Stater, 95119
        • Kaiser Permanente-Santa Teresa-San Jose
      • San Jose, California, Forenede Stater, 95124
        • Stanford Cancer Center South Bay
      • San Leandro, California, Forenede Stater, 94577
        • Kaiser Permanente San Leandro
      • San Marcos, California, Forenede Stater, 92078
        • Kaiser Permanente-San Marcos
      • San Rafael, California, Forenede Stater, 94903
        • Kaiser San Rafael-Gallinas
      • San Rafael, California, Forenede Stater, 94903
        • Kaiser Permanente-San Rafael
      • Santa Clara, California, Forenede Stater, 95051
        • Kaiser Permanente Medical Center - Santa Clara
      • Santa Cruz, California, Forenede Stater, 95065
        • Palo Alto Medical Foundation-Santa Cruz
      • Santa Cruz, California, Forenede Stater, 95065
        • Dominican Santa Cruz Hospital
      • Santa Rosa, California, Forenede Stater, 95403
        • Kaiser Permanente-Santa Rosa
      • Santa Rosa, California, Forenede Stater, 95403
        • Sutter Pacific Medical Foundation
      • South San Francisco, California, Forenede Stater, 94080
        • Kaiser Permanente-South San Francisco
      • Stockton, California, Forenede Stater, 95210
        • Kaiser Permanente-Stockton
      • Stockton, California, Forenede Stater, 95204
        • Saint Joseph's Medical Center
      • Sunnyvale, California, Forenede Stater, 94086
        • Palo Alto Medical Foundation-Sunnyvale
      • Truckee, California, Forenede Stater, 96161
        • Gene Upshaw Memorial Tahoe Forest Cancer Center
      • Vacaville, California, Forenede Stater, 95688
        • Kaiser Permanente Medical Center-Vacaville
      • Vacaville, California, Forenede Stater, 95687
        • Northbay Cancer Center
      • Vacaville, California, Forenede Stater, 95687
        • Sutter Cancer Centers Radiation Oncology Services-Vacaville
      • Vallejo, California, Forenede Stater, 94589
        • Kaiser Permanente-Vallejo
      • Vallejo, California, Forenede Stater, 94589
        • Sutter Solano Medical Center/Cancer Center
      • Walnut Creek, California, Forenede Stater, 94596
        • Kaiser Permanente-Walnut Creek
      • Walnut Creek, California, Forenede Stater, 94597
        • Epic Care Cyberknife Center
      • Woodland, California, Forenede Stater, 95695
        • Woodland Memorial Hospital
      • Woodland Hills, California, Forenede Stater, 91367
        • Kaiser Permanente-Woodland Hills
    • Colorado
      • Aurora, Colorado, Forenede Stater, 80012
        • Rocky Mountain Cancer Centers-Aurora
      • Aurora, Colorado, Forenede Stater, 80012
        • The Medical Center of Aurora
      • Boulder, Colorado, Forenede Stater, 80301
        • Boulder Community Hospital
      • Boulder, Colorado, Forenede Stater, 80304
        • Rocky Mountain Cancer Centers-Boulder
      • Colorado Springs, Colorado, Forenede Stater, 80907
        • Penrose-Saint Francis Healthcare
      • Colorado Springs, Colorado, Forenede Stater, 80907
        • Rocky Mountain Cancer Centers-Penrose
      • Denver, Colorado, Forenede Stater, 80210
        • Porter Adventist Hospital
      • Denver, Colorado, Forenede Stater, 80205
        • Kaiser Permanente-Franklin
      • Denver, Colorado, Forenede Stater, 80218
        • Presbyterian - Saint Lukes Medical Center - Health One
      • Denver, Colorado, Forenede Stater, 80218
        • SCL Health Saint Joseph Hospital
      • Denver, Colorado, Forenede Stater, 80220
        • Rose Medical Center
      • Denver, Colorado, Forenede Stater, 80218
        • Rocky Mountain Cancer Centers-Midtown
      • Denver, Colorado, Forenede Stater, 80220
        • Rocky Mountain Cancer Centers-Rose
      • Denver, Colorado, Forenede Stater, 80204
        • Denver Health Medical Center
      • Denver, Colorado, Forenede Stater, 80218
        • Colorado Blood Cancer Institute
      • Denver, Colorado, Forenede Stater, 80209
        • The Women's Imaging Center
      • Denver, Colorado, Forenede Stater, 80206
        • National Jewish Health-Main Campus
      • Durango, Colorado, Forenede Stater, 81301
        • Mercy Medical Center
      • Durango, Colorado, Forenede Stater, 81301
        • Southwest Oncology PC
      • Englewood, Colorado, Forenede Stater, 80113
        • Swedish Medical Center
      • Englewood, Colorado, Forenede Stater, 80113
        • Comprehensive Cancer Care and Research Institute of Colorado LLC
      • Golden, Colorado, Forenede Stater, 80401
        • Mountain Blue Cancer Care Center
      • Golden, Colorado, Forenede Stater, 80401
        • National Jewish Health-Western Hematology Oncology
      • Grand Junction, Colorado, Forenede Stater, 81501
        • Saint Mary's Hospital and Regional Medical Center
      • Grand Junction, Colorado, Forenede Stater, 81505
        • Grand Valley Oncology
      • Greeley, Colorado, Forenede Stater, 80631
        • North Colorado Medical Center
      • Greenwood Village, Colorado, Forenede Stater, 80111
        • Rocky Mountain Cancer Centers-Greenwood Village
      • Lafayette, Colorado, Forenede Stater, 80026
        • Kaiser Permanente-Rock Creek
      • Lakewood, Colorado, Forenede Stater, 80228
        • Saint Anthony Hospital
      • Lakewood, Colorado, Forenede Stater, 80228
        • Rocky Mountain Cancer Centers-Lakewood
      • Littleton, Colorado, Forenede Stater, 80120
        • Rocky Mountain Cancer Centers-Littleton
      • Littleton, Colorado, Forenede Stater, 80122
        • Littleton Adventist Hospital
      • Lone Tree, Colorado, Forenede Stater, 80124
        • Kaiser Permanente-Lone Tree
      • Lone Tree, Colorado, Forenede Stater, 80124
        • Sky Ridge Medical Center
      • Lone Tree, Colorado, Forenede Stater, 80124
        • Rocky Mountain Cancer Centers-Sky Ridge
      • Longmont, Colorado, Forenede Stater, 80501
        • Longmont United Hospital
      • Longmont, Colorado, Forenede Stater, 80501
        • Rocky Mountain Cancer Centers-Longmont
      • Loveland, Colorado, Forenede Stater, 80539
        • McKee Medical Center
      • Parker, Colorado, Forenede Stater, 80138
        • Parker Adventist Hospital
      • Parker, Colorado, Forenede Stater, 80138
        • Rocky Mountain Cancer Centers-Parker
      • Pueblo, Colorado, Forenede Stater, 81004
        • Saint Mary Corwin Medical Center
      • Pueblo, Colorado, Forenede Stater, 81008
        • Rocky Mountain Cancer Centers - Pueblo
      • Thornton, Colorado, Forenede Stater, 80260
        • Rocky Mountain Cancer Centers-Thornton
      • Thornton, Colorado, Forenede Stater, 80260
        • National Jewish Health-Northern Hematology Oncology
      • Wheat Ridge, Colorado, Forenede Stater, 80033
        • SCL Health Lutheran Medical Center
    • Connecticut
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        • Saint Vincent's Medical Center
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        • Smilow Cancer Hospital-Derby Care Center
      • Fairfield, Connecticut, Forenede Stater, 06824
        • Smilow Cancer Hospital Care Center-Fairfield
      • Greenwich, Connecticut, Forenede Stater, 06830
        • Greenwich Hospital
      • Guilford, Connecticut, Forenede Stater, 06437
        • Yale-New Haven Shoreline Medical Center
      • Hartford, Connecticut, Forenede Stater, 06105
        • Smilow Cancer Hospital Care Center at Saint Francis
      • Hartford, Connecticut, Forenede Stater, 06102
        • Hartford Hospital
      • Meriden, Connecticut, Forenede Stater, 06451
        • Midstate Medical Center
      • Middletown, Connecticut, Forenede Stater, 06457
        • Middlesex Hospital
      • New Britain, Connecticut, Forenede Stater, 06050
        • The Hospital of Central Connecticut
      • New Haven, Connecticut, Forenede Stater, 06520
        • Yale University
      • New Haven, Connecticut, Forenede Stater, 06510
        • Smilow Cancer Center/Yale-New Haven Hospital
      • North Haven, Connecticut, Forenede Stater, 06473
        • Yale-New Haven Hospital North Haven Medical Center
      • Norwich, Connecticut, Forenede Stater, 06360
        • William Backus Hospital
      • Orange, Connecticut, Forenede Stater, 06477
        • Smilow Cancer Hospital-Orange Care Center
      • Torrington, Connecticut, Forenede Stater, 06790
        • Smilow Cancer Hospital-Torrington Care Center
      • Trumbull, Connecticut, Forenede Stater, 06611
        • Smilow Cancer Hospital Care Center-Trumbull
      • Waterbury, Connecticut, Forenede Stater, 06708
        • Smilow Cancer Hospital-Waterbury Care Center
      • Waterford, Connecticut, Forenede Stater, 06385
        • Lawrence and Memorial Cancer Center
    • Delaware
      • Dover, Delaware, Forenede Stater, 19901
        • Bayhealth Hospital Kent Campus
      • Lewes, Delaware, Forenede Stater, 19958
        • Beebe Medical Center
      • Milford, Delaware, Forenede Stater, 19963
        • Bayhealth Hospital Sussex Campus
      • Newark, Delaware, Forenede Stater, 19713
        • Helen F Graham Cancer Center
      • Newark, Delaware, Forenede Stater, 19713
        • Delaware Clinical and Laboratory Physicians PA
      • Newark, Delaware, Forenede Stater, 19713
        • Medical Oncology Hematology Consultants PA
      • Newark, Delaware, Forenede Stater, 19718
        • Christiana Care Health System-Christiana Hospital
      • Newark, Delaware, Forenede Stater, 19713
        • Christiana Gynecologic Oncology LLC
      • Newark, Delaware, Forenede Stater, 19713
        • Regional Hematology and Oncology PA
      • Rehoboth Beach, Delaware, Forenede Stater, 19971
        • Beebe Health Campus
      • Seaford, Delaware, Forenede Stater, 19973
        • Nanticoke Memorial Hospital
      • Wilmington, Delaware, Forenede Stater, 19801
        • Christiana Care Health System-Wilmington Hospital
    • District of Columbia
      • Washington D.C., District of Columbia, Forenede Stater, 20010
        • Medstar Washington Hospital Center
      • Washington D.C., District of Columbia, Forenede Stater, 20002
        • Kaiser Permanente-Capitol Hill Medical Center
      • Washington D.C., District of Columbia, Forenede Stater, 20007
        • MedStar Georgetown University Hospital
      • Washington D.C., District of Columbia, Forenede Stater, 20016
        • Sibley Memorial Hospital
    • Florida
      • Aventura, Florida, Forenede Stater, 33180
        • Mount Sinai Comprehensive Cancer Center at Aventura
      • Clearwater, Florida, Forenede Stater, 33756
        • Morton Plant Hospital
      • Coral Gables, Florida, Forenede Stater, 33146
        • UM Sylvester Comprehensive Cancer Center at Coral Gables
      • Daytona Beach, Florida, Forenede Stater, 32114
        • Halifax Health Medical Center-Centers for Oncology
      • Deerfield Beach, Florida, Forenede Stater, 33442
        • UM Sylvester Comprehensive Cancer Center at Deerfield Beach
      • Fort Lauderdale, Florida, Forenede Stater, 33308
        • Holy Cross Hospital
      • Fort Myers, Florida, Forenede Stater, 33905
        • Regional Cancer Center-Lee Memorial Health System
      • Lakeland, Florida, Forenede Stater, 33805
        • Lakeland Regional Health Hollis Cancer Center
      • Lakeland, Florida, Forenede Stater, 33805
        • The Watson Clinic
      • Miami, Florida, Forenede Stater, 33136
        • University of Miami Miller School of Medicine-Sylvester Cancer Center
      • Miami, Florida, Forenede Stater, 33176
        • UM Sylvester Comprehensive Cancer Center at Kendall
      • Miami Beach, Florida, Forenede Stater, 33140
        • Mount Sinai Medical Center
      • Orlando, Florida, Forenede Stater, 32806
        • UF Cancer Center at Orlando Health
      • Plantation, Florida, Forenede Stater, 33324
        • UM Sylvester Comprehensive Cancer Center at Plantation
      • Tallahassee, Florida, Forenede Stater, 32308
        • Tallahassee Memorial HealthCare
      • Tampa, Florida, Forenede Stater, 33607
        • Saint Joseph's Hospital/Children's Hospital-Tampa
      • Weston, Florida, Forenede Stater, 33331
        • Cleveland Clinic-Weston
    • Georgia
      • Albany, Georgia, Forenede Stater, 31701
        • Phoebe Putney Memorial Hospital
      • Athens, Georgia, Forenede Stater, 30607
        • University Cancer and Blood Center LLC
      • Atlanta, Georgia, Forenede Stater, 30342
        • Northside Hospital
      • Augusta, Georgia, Forenede Stater, 30912
        • Augusta University Medical Center
      • Cumming, Georgia, Forenede Stater, 30041
        • Northside Hospital-Forsyth
      • Decatur, Georgia, Forenede Stater, 30033
        • Dekalb Medical Center
      • Rome, Georgia, Forenede Stater, 30165
        • Harbin Clinic Medical Oncology and Clinical Research
      • Savannah, Georgia, Forenede Stater, 31405
        • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
      • Savannah, Georgia, Forenede Stater, 31404
        • Memorial Health University Medical Center
      • Savannah, Georgia, Forenede Stater, 31404
        • Summit Cancer Care-Memorial
      • Savannah, Georgia, Forenede Stater, 31405
        • Low Country Cancer Care Associates PC
      • Valdosta, Georgia, Forenede Stater, 31602
        • South Georgia Medical Center/Pearlman Cancer Center
    • Hawaii
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Queen's Medical Center
      • Honolulu, Hawaii, Forenede Stater, 96817
        • The Cancer Center of Hawaii-Liliha
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Straub Clinic and Hospital
      • Honolulu, Hawaii, Forenede Stater, 96813
        • University of Hawaii Cancer Center
      • Honolulu, Hawaii, Forenede Stater, 96817
        • Hawaii Cancer Care Inc-Liliha
      • Honolulu, Hawaii, Forenede Stater, 96817
        • Kuakini Medical Center
      • Honolulu, Hawaii, Forenede Stater, 96826
        • Kapiolani Medical Center for Women and Children
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Island Urology
      • Honolulu, Hawaii, Forenede Stater, 96819
        • Kaiser Permanente Moanalua Medical Center
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Hawaii Cancer Care Inc-POB II
      • Honolulu, Hawaii, Forenede Stater, 96813
        • Hawaii Oncology Inc-POB I
      • Honolulu, Hawaii, Forenede Stater, 96817
        • Hawaii Oncology Inc-Kuakini
      • Lihue, Hawaii, Forenede Stater, 96766
        • Wilcox Memorial Hospital and Kauai Medical Clinic
      • ‘Aiea, Hawaii, Forenede Stater, 96701
        • Pali Momi Medical Center
      • ‘Aiea, Hawaii, Forenede Stater, 96701
        • The Cancer Center of Hawaii-Pali Momi
      • ‘Aiea, Hawaii, Forenede Stater, 96701
        • Hawaii Oncology Inc-Pali Momi
    • Idaho
      • Boise, Idaho, Forenede Stater, 83706
        • Saint Alphonsus Cancer Care Center-Boise
      • Boise, Idaho, Forenede Stater, 83712
        • Saint Luke's Mountain States Tumor Institute
      • Caldwell, Idaho, Forenede Stater, 83605
        • Saint Alphonsus Cancer Care Center-Caldwell
      • Coeur d'Alene, Idaho, Forenede Stater, 83814
        • Kootenai Medical Center
      • Emmett, Idaho, Forenede Stater, 83617
        • Walter Knox Memorial Hospital
      • Fruitland, Idaho, Forenede Stater, 83619
        • Saint Luke's Mountain States Tumor Institute - Fruitland
      • Meridian, Idaho, Forenede Stater, 83642
        • Idaho Urologic Institute-Meridian
      • Meridian, Idaho, Forenede Stater, 83642
        • Saint Luke's Mountain States Tumor Institute - Meridian
      • Nampa, Idaho, Forenede Stater, 83686
        • Saint Alphonsus Medical Center-Nampa
      • Nampa, Idaho, Forenede Stater, 83686
        • Saint Luke's Mountain States Tumor Institute - Nampa
      • Post Falls, Idaho, Forenede Stater, 83854
        • Kootenai Cancer Center
      • Sandpoint, Idaho, Forenede Stater, 83864
        • Kootenai Cancer Clinic
      • Twin Falls, Idaho, Forenede Stater, 83301
        • Saint Luke's Mountain States Tumor Institute-Twin Falls
    • Illinois
      • Arlington Heights, Illinois, Forenede Stater, 60005
        • Northwest Community Hospital
      • Aurora, Illinois, Forenede Stater, 60504
        • Rush - Copley Medical Center
      • Berwyn, Illinois, Forenede Stater, 60402
        • Mac Neal Hospital
      • Bloomington, Illinois, Forenede Stater, 61704
        • Illinois CancerCare-Bloomington
      • Bloomington, Illinois, Forenede Stater, 61701
        • Saint Joseph Medical Center
      • Canton, Illinois, Forenede Stater, 61520
        • Illinois CancerCare-Canton
      • Carbondale, Illinois, Forenede Stater, 62902
        • Memorial Hospital of Carbondale
      • Carterville, Illinois, Forenede Stater, 62918
        • SIH Cancer Institute
      • Carthage, Illinois, Forenede Stater, 62321
        • Illinois CancerCare-Carthage
      • Centralia, Illinois, Forenede Stater, 62801
        • Centralia Oncology Clinic
      • Chicago, Illinois, Forenede Stater, 60611
        • Northwestern University
      • Chicago, Illinois, Forenede Stater, 60637
        • University of Chicago Comprehensive Cancer Center
      • Chicago, Illinois, Forenede Stater, 60612
        • University of Illinois
      • Chicago, Illinois, Forenede Stater, 60612
        • John H Stroger Jr Hospital of Cook County
      • Chicago, Illinois, Forenede Stater, 60640
        • Weiss Memorial Hospital
      • Chicago, Illinois, Forenede Stater, 60657
        • Presence Saint Joseph Hospital-Chicago
      • Danville, Illinois, Forenede Stater, 61832
        • Carle on Vermilion
      • Decatur, Illinois, Forenede Stater, 62526
        • Decatur Memorial Hospital
      • Decatur, Illinois, Forenede Stater, 62526
        • Cancer Care Specialists of Illinois - Decatur
      • Effingham, Illinois, Forenede Stater, 62401
        • Crossroads Cancer Center
      • Effingham, Illinois, Forenede Stater, 62401
        • Carle Physician Group-Effingham
      • Elmhurst, Illinois, Forenede Stater, 60126
        • Elmhurst Memorial Hospital
      • Eureka, Illinois, Forenede Stater, 61530
        • Illinois CancerCare-Eureka
      • Galesburg, Illinois, Forenede Stater, 61401
        • Western Illinois Cancer Treatment Center
      • Galesburg, Illinois, Forenede Stater, 61401
        • Illinois CancerCare-Galesburg
      • Geneva, Illinois, Forenede Stater, 60134
        • Northwestern Medicine Cancer Center Delnor
      • Harvey, Illinois, Forenede Stater, 60426
        • Ingalls Memorial Hospital
      • Hinsdale, Illinois, Forenede Stater, 60521
        • AMITA Health Cancer Institute and Outpatient Center
      • Joliet, Illinois, Forenede Stater, 60435
        • Joliet Oncology-Hematology Associates Limited
      • Kankakee, Illinois, Forenede Stater, 60901
        • Presence Saint Mary's Hospital
      • Kewanee, Illinois, Forenede Stater, 61443
        • Illinois CancerCare-Kewanee Clinic
      • Lake Forest, Illinois, Forenede Stater, 60045
        • Northwestern Medicine Lake Forest Hospital
      • Macomb, Illinois, Forenede Stater, 61455
        • Illinois CancerCare-Macomb
      • Mattoon, Illinois, Forenede Stater, 61938
        • Carle Physician Group-Mattoon/Charleston
      • Maywood, Illinois, Forenede Stater, 60153
        • Loyola University Medical Center
      • Moline, Illinois, Forenede Stater, 61265
        • Garneau, Stewart C MD (UIA Investigator)
      • Moline, Illinois, Forenede Stater, 61265
        • Spector, David MD (UIA Investigator)
      • Moline, Illinois, Forenede Stater, 61265
        • Trinity Medical Center
      • Mount Vernon, Illinois, Forenede Stater, 62864
        • Good Samaritan Regional Health Center
      • Naperville, Illinois, Forenede Stater, 60540
        • Edward Hospital/Cancer Center
      • New Lenox, Illinois, Forenede Stater, 60451
        • UC Comprehensive Cancer Center at Silver Cross
      • Ottawa, Illinois, Forenede Stater, 61350
        • Illinois CancerCare-Ottawa Clinic
      • Ottawa, Illinois, Forenede Stater, 61350
        • Radiation Oncology of Northern Illinois
      • Park Ridge, Illinois, Forenede Stater, 60068
        • Advocate Lutheran General Hospital
      • Pekin, Illinois, Forenede Stater, 61554
        • Illinois CancerCare-Pekin
      • Pekin, Illinois, Forenede Stater, 61554
        • OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
      • Peoria, Illinois, Forenede Stater, 61636
        • Methodist Medical Center of Illinois
      • Peoria, Illinois, Forenede Stater, 61637
        • OSF Saint Francis Medical Center
      • Peoria, Illinois, Forenede Stater, 61615
        • Illinois CancerCare-Peoria
      • Peoria, Illinois, Forenede Stater, 61615
        • OSF Saint Francis Radiation Oncology at Peoria Cancer Center
      • Peru, Illinois, Forenede Stater, 61354
        • Illinois CancerCare-Peru
      • Peru, Illinois, Forenede Stater, 61354
        • Valley Radiation Oncology
      • Plainfield, Illinois, Forenede Stater, 60585
        • Edward Hospital/Cancer Center?Plainfield
      • Princeton, Illinois, Forenede Stater, 61356
        • Illinois CancerCare-Princeton
      • River Forest, Illinois, Forenede Stater, 60305
        • West Suburban Medical Center
      • Rockford, Illinois, Forenede Stater, 61114
        • SwedishAmerican Regional Cancer Center/ACT
      • Silvis, Illinois, Forenede Stater, 61282
        • Genesis Cancer Center - Silvis
      • Springfield, Illinois, Forenede Stater, 62781
        • Memorial Medical Center
      • Springfield, Illinois, Forenede Stater, 62702
        • Southern Illinois University School of Medicine
      • Springfield, Illinois, Forenede Stater, 62702
        • Springfield Clinic
      • Springfield, Illinois, Forenede Stater, 62702
        • Central Illinois Hematology Oncology Center
      • Swansea, Illinois, Forenede Stater, 62226
        • Southwest Illinois Health Services LLP
      • Swansea, Illinois, Forenede Stater, 62226
        • Cancer Care Specialists of Illinois-Swansea
      • Urbana, Illinois, Forenede Stater, 61801
        • Carle Cancer Center
      • Urbana, Illinois, Forenede Stater, 61801
        • The Carle Foundation Hospital
      • Warrenville, Illinois, Forenede Stater, 60555
        • Northwestern Medicine Cancer Center Warrenville
      • Yorkville, Illinois, Forenede Stater, 60560
        • Rush-Copley Healthcare Center
      • Zion, Illinois, Forenede Stater, 60099
        • Midwestern Regional Medical Center
    • Indiana
      • Evansville, Indiana, Forenede Stater, 47713
        • Deaconess Clinic Downtown
      • Goshen, Indiana, Forenede Stater, 46526
        • Goshen Center for Cancer Care
      • Indianapolis, Indiana, Forenede Stater, 46237
        • Franciscan Health Indianapolis
      • Indianapolis, Indiana, Forenede Stater, 46202
        • Indiana University/Melvin and Bren Simon Cancer Center
      • Indianapolis, Indiana, Forenede Stater, 46202
        • Sidney and Lois Eskenazi Hospital
      • Indianapolis, Indiana, Forenede Stater, 46290
        • Springmill Medical Center
      • Michigan City, Indiana, Forenede Stater, 46360
        • Franciscan Saint Anthony Health-Michigan City
      • Michigan City, Indiana, Forenede Stater, 46360
        • Woodland Cancer Care Center
      • Mishawaka, Indiana, Forenede Stater, 46545
        • Memorial Regional Cancer Center Day Road
      • Mooresville, Indiana, Forenede Stater, 46158
        • Franciscan Health Mooresville
      • Muncie, Indiana, Forenede Stater, 47303
        • IU Health Ball Memorial Hospital
      • Munster, Indiana, Forenede Stater, 46321
        • The Community Hospital
      • Newburgh, Indiana, Forenede Stater, 47630
        • Chancellor Center for Oncology
      • Richmond, Indiana, Forenede Stater, 47374
        • Reid Health
      • South Bend, Indiana, Forenede Stater, 46601
        • Memorial Hospital of South Bend
      • Terre Haute, Indiana, Forenede Stater, 47804
        • Union Hospital
    • Iowa
      • Ames, Iowa, Forenede Stater, 50010
        • McFarland Clinic PC - Ames
      • Ames, Iowa, Forenede Stater, 50010
        • Mary Greeley Medical Center
      • Bettendorf, Iowa, Forenede Stater, 52722
        • Constantinou, Costas L MD (UIA Investigator)
      • Bettendorf, Iowa, Forenede Stater, 52722
        • University of Iowa Healthcare Cancer Services Quad Cities
      • Boone, Iowa, Forenede Stater, 50036
        • McFarland Clinic PC-Boone
      • Cedar Rapids, Iowa, Forenede Stater, 52403
        • Mercy Hospital
      • Cedar Rapids, Iowa, Forenede Stater, 52403
        • Oncology Associates at Mercy Medical Center
      • Clive, Iowa, Forenede Stater, 50325
        • Mercy Cancer Center-West Lakes
      • Clive, Iowa, Forenede Stater, 50325
        • Medical Oncology and Hematology Associates-West Des Moines
      • Council Bluffs, Iowa, Forenede Stater, 51503
        • Alegent Health Mercy Hospital
      • Creston, Iowa, Forenede Stater, 50801
        • Greater Regional Medical Center
      • Davenport, Iowa, Forenede Stater, 52803
        • Genesis Medical Center - East Campus
      • Davenport, Iowa, Forenede Stater, 52804
        • Genesis Cancer Care Institute
      • Davenport, Iowa, Forenede Stater, 52807
        • Iowa Cancer Specialists
      • Des Moines, Iowa, Forenede Stater, 50309
        • Iowa Methodist Medical Center
      • Des Moines, Iowa, Forenede Stater, 50314
        • Mercy Medical Center - Des Moines
      • Des Moines, Iowa, Forenede Stater, 50309
        • Medical Oncology and Hematology Associates-Des Moines
      • Des Moines, Iowa, Forenede Stater, 50314
        • Broadlawns Medical Center
      • Des Moines, Iowa, Forenede Stater, 50316
        • Iowa Lutheran Hospital
      • Des Moines, Iowa, Forenede Stater, 50314
        • Medical Oncology and Hematology Associates-Laurel
      • Fairfield, Iowa, Forenede Stater, 52556
        • JCHC McCreery Cancer Center
      • Fort Dodge, Iowa, Forenede Stater, 50501
        • McFarland Clinic PC-Trinity Cancer Center
      • Iowa City, Iowa, Forenede Stater, 52242
        • University of Iowa/Holden Comprehensive Cancer Center
      • Jefferson, Iowa, Forenede Stater, 50129
        • McFarland Clinic PC-Jefferson
      • Marshalltown, Iowa, Forenede Stater, 50158
        • McFarland Clinic PC-Marshalltown
      • Mason City, Iowa, Forenede Stater, 50401
        • Mercy Medical Center - North Iowa
      • Ottumwa, Iowa, Forenede Stater, 52501
        • Ottumwa Regional Health Center
      • Sioux City, Iowa, Forenede Stater, 51101
        • Siouxland Regional Cancer Center
      • West Des Moines, Iowa, Forenede Stater, 50266-7700
        • Methodist West Hospital
      • West Des Moines, Iowa, Forenede Stater, 50266
        • Mercy Medical Center-West Lakes
    • Kansas
      • Chanute, Kansas, Forenede Stater, 66720
        • Cancer Center of Kansas - Chanute
      • Dodge City, Kansas, Forenede Stater, 67801
        • Cancer Center of Kansas - Dodge City
      • El Dorado, Kansas, Forenede Stater, 67042
        • Cancer Center of Kansas - El Dorado
      • Fort Scott, Kansas, Forenede Stater, 66701
        • Cancer Center of Kansas - Fort Scott
      • Garden City, Kansas, Forenede Stater, 67846
        • Central Care Cancer Center - Garden City
      • Great Bend, Kansas, Forenede Stater, 67530
        • Central Care Cancer Center - Great Bend
      • Independence, Kansas, Forenede Stater, 67301
        • Cancer Center of Kansas-Independence
      • Kingman, Kansas, Forenede Stater, 67068
        • Cancer Center of Kansas-Kingman
      • Lawrence, Kansas, Forenede Stater, 66044
        • Lawrence Memorial Hospital
      • Lenexa, Kansas, Forenede Stater, 66219
        • Kansas Institute of Medicine Cancer and Blood Center
      • Lenexa, Kansas, Forenede Stater, 66219
        • Minimally Invasive Surgery Hospital
      • Liberal, Kansas, Forenede Stater, 67905
        • Cancer Center of Kansas-Liberal
      • Manhattan, Kansas, Forenede Stater, 66502
        • Cancer Center of Kansas-Manhattan
      • McPherson, Kansas, Forenede Stater, 67460
        • Cancer Center of Kansas - McPherson
      • Newton, Kansas, Forenede Stater, 67114
        • Cancer Center of Kansas - Newton
      • Overland Park, Kansas, Forenede Stater, 66209
        • Menorah Medical Center
      • Overland Park, Kansas, Forenede Stater, 66213
        • Saint Luke's South Hospital
      • Parsons, Kansas, Forenede Stater, 67357
        • Cancer Center of Kansas - Parsons
      • Pratt, Kansas, Forenede Stater, 67124
        • Cancer Center of Kansas - Pratt
      • Salina, Kansas, Forenede Stater, 67401
        • Cancer Center of Kansas - Salina
      • Topeka, Kansas, Forenede Stater, 66606
        • Cotton O'Neil Cancer Center / Stormont Vail Health
      • Wellington, Kansas, Forenede Stater, 67152
        • Cancer Center of Kansas - Wellington
      • Wichita, Kansas, Forenede Stater, 67208
        • Cancer Center of Kansas-Wichita Medical Arts Tower
      • Wichita, Kansas, Forenede Stater, 67214
        • Cancer Center of Kansas - Wichita
      • Wichita, Kansas, Forenede Stater, 67208
        • Associates In Womens Health
      • Wichita, Kansas, Forenede Stater, 67214
        • Via Christi Regional Medical Center
      • Winfield, Kansas, Forenede Stater, 67156
        • Cancer Center of Kansas - Winfield
    • Kentucky
      • Bardstown, Kentucky, Forenede Stater, 40004
        • Flaget Memorial Hospital
      • Corbin, Kentucky, Forenede Stater, 40701
        • Baptist Health Corbin
      • Corbin, Kentucky, Forenede Stater, 40701
        • Commonwealth Cancer Center-Corbin
      • Crestview Hills, Kentucky, Forenede Stater, 41017
        • Oncology Hematology Care Inc-Crestview
      • Edgewood, Kentucky, Forenede Stater, 41017
        • Saint Elizabeth Medical Center South
      • Elizabethtown, Kentucky, Forenede Stater, 42701
        • Hardin Memorial Hospital
      • Fort Thomas, Kentucky, Forenede Stater, 41075
        • Saint Elizabeth Fort Thomas
      • Lexington, Kentucky, Forenede Stater, 40536
        • University of Kentucky/Markey Cancer Center
      • Lexington, Kentucky, Forenede Stater, 40504
        • Saint Joseph Radiation Oncology Resource Center
      • Lexington, Kentucky, Forenede Stater, 40509
        • Saint Joseph Hospital East
      • Lexington, Kentucky, Forenede Stater, 40503
        • Baptist Health Lexington
      • Louisville, Kentucky, Forenede Stater, 40202
        • Norton Hospital Pavilion and Medical Campus
      • Louisville, Kentucky, Forenede Stater, 40241
        • Norton Brownsboro Hospital and Medical Campus
      • Louisville, Kentucky, Forenede Stater, 40202
        • Jewish Hospital
      • Louisville, Kentucky, Forenede Stater, 40207
        • Norton Suburban Hospital and Medical Campus
      • Louisville, Kentucky, Forenede Stater, 40207
        • Baptist Health Louisville
      • Louisville, Kentucky, Forenede Stater, 40215
        • Saints Mary and Elizabeth Hospital
      • Louisville, Kentucky, Forenede Stater, 40217
        • Norton Audubon Hospital and Medical Campus
      • Louisville, Kentucky, Forenede Stater, 40245
        • Jewish Hospital Medical Center Northeast
      • Madisonville, Kentucky, Forenede Stater, 42431
        • Baptist Health Madisonville/Merle Mahr Cancer Center
      • Paducah, Kentucky, Forenede Stater, 42003
        • Baptist Health Paducah
      • Shepherdsville, Kentucky, Forenede Stater, 40165
        • Jewish Hospital Medical Center South
    • Louisiana
      • Alexandria, Louisiana, Forenede Stater, 71301
        • Christus Saint Frances Cabrini Hospital
      • Baton Rouge, Louisiana, Forenede Stater, 70805
        • LSU Health Baton Rouge-North Clinic
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Louisiana Hematology Oncology Associates LLC
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Mary Bird Perkins Cancer Center
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Our Lady of the Lake Physicians Group - Medical Oncology
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Ochsner Health Center-Summa
      • Baton Rouge, Louisiana, Forenede Stater, 70816
        • Medical Center of Baton Rouge
      • Baton Rouge, Louisiana, Forenede Stater, 70836
        • Ochsner High Grove
      • Baton Rouge, Louisiana, Forenede Stater, 70806
        • Baton Rouge General Medical Center
      • Baton Rouge, Louisiana, Forenede Stater, 70809
        • Hematology/Oncology Clinic LLP
      • Baton Rouge, Louisiana, Forenede Stater, 70817
        • Woman's Hospital
      • Covington, Louisiana, Forenede Stater, 70433
        • Mary Bird Perkins Cancer Center - Covington
      • Covington, Louisiana, Forenede Stater, 70433
        • Northshore Oncology Associates-Covington
      • Houma, Louisiana, Forenede Stater, 70360
        • Mary Bird Perkins Cancer Center - Houma
      • Houma, Louisiana, Forenede Stater, 70360
        • Oncology Center of The South Incorporated
      • Kenner, Louisiana, Forenede Stater, 70065
        • Ochsner Medical Center Kenner
      • Lake Charles, Louisiana, Forenede Stater, 70601
        • CHRISTUS Saint Patrick Hospital
      • Marrero, Louisiana, Forenede Stater, 70072
        • West Jefferson Medical Center
      • Monroe, Louisiana, Forenede Stater, 71202
        • University Health-Conway
      • New Orleans, Louisiana, Forenede Stater, 70121
        • Ochsner Medical Center Jefferson
      • New Orleans, Louisiana, Forenede Stater, 70112
        • Tulane University Health Sciences Center
      • Shreveport, Louisiana, Forenede Stater, 71103
        • Louisiana State University Health Sciences Center Shreveport
      • Shreveport, Louisiana, Forenede Stater, 71105
        • CHRISTUS Highland Medical Center
    • Maine
      • Augusta, Maine, Forenede Stater, 04330
        • Harold Alfond Center for Cancer Care
      • Bangor, Maine, Forenede Stater, 04401
        • Eastern Maine Medical Center
      • Belfast, Maine, Forenede Stater, 04915
        • Waldo County General Hospital
      • Biddeford, Maine, Forenede Stater, 04005
        • MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford
      • Brewer, Maine, Forenede Stater, 04412
        • Lafayette Family Cancer Center-EMMC
      • Lewiston, Maine, Forenede Stater, 04240
        • Central Maine Medical Center
      • Norway, Maine, Forenede Stater, 04268
        • Stephens Memorial Hospital
      • Portland, Maine, Forenede Stater, 04101
        • Mercy Hospital
      • Rockport, Maine, Forenede Stater, 04856
        • Penobscot Bay Medical Center
      • Sanford, Maine, Forenede Stater, 04073
        • MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford
      • Scarborough, Maine, Forenede Stater, 04074
        • Maine Medical Center- Scarborough Campus
      • South Portland, Maine, Forenede Stater, 04106
        • Maine Medical Partners - South Portland
    • Maryland
      • Baltimore, Maryland, Forenede Stater, 21237
        • MedStar Franklin Square Medical Center/Weinberg Cancer Institute
      • Baltimore, Maryland, Forenede Stater, 21287
        • Johns Hopkins University/Sidney Kimmel Cancer Center
      • Baltimore, Maryland, Forenede Stater, 21215
        • Sinai Hospital of Baltimore
      • Baltimore, Maryland, Forenede Stater, 21201
        • University of Maryland/Greenebaum Cancer Center
      • Baltimore, Maryland, Forenede Stater, 21202
        • Mercy Medical Center
      • Baltimore, Maryland, Forenede Stater, 21218
        • MedStar Union Memorial Hospital
      • Baltimore, Maryland, Forenede Stater, 21229
        • Saint Agnes Hospital
      • Baltimore, Maryland, Forenede Stater, 21244
        • Kaiser Permanente-Woodlawn Medical Center
      • Baltimore, Maryland, Forenede Stater, 21239
        • MedStar Good Samaritan Hospital
      • Bel Air, Maryland, Forenede Stater, 21014
        • UM Upper Chesapeake Medical Center
      • Easton, Maryland, Forenede Stater, 21601
        • University of Maryland Shore Medical Center at Easton
      • Elkton, Maryland, Forenede Stater, 21921
        • Union Hospital of Cecil County
      • Frederick, Maryland, Forenede Stater, 21701
        • Frederick Memorial Hospital
      • Gaithersburg, Maryland, Forenede Stater, 20879
        • Kaiser Permanente-Gaithersburg Medical Center
      • Kensington, Maryland, Forenede Stater, 20895
        • Kaiser Permanente - Kensington Medical Center
      • Largo, Maryland, Forenede Stater, 20774
        • Kaiser Permanente - Largo Medical Center
      • Ocean Pines, Maryland, Forenede Stater, 21811
        • Richard A Henson Cancer Institute at Ocean Pines
      • Randallstown, Maryland, Forenede Stater, 21133
        • Northwest Hospital Center
      • Rockville, Maryland, Forenede Stater, 20850
        • Maryland Oncology Hematology PA-Aquilino Cancer Center
      • Salisbury, Maryland, Forenede Stater, 21801
        • Peninsula Regional Medical Center
      • Silver Spring, Maryland, Forenede Stater, 20910
        • Holy Cross Hospital
      • Westminster, Maryland, Forenede Stater, 21157
        • William E Kahlert Regional Cancer Center/Sinai Hospital
    • Massachusetts
      • Beverly, Massachusetts, Forenede Stater, 01915
        • Beverly Hospital
      • Boston, Massachusetts, Forenede Stater, 02215
        • Beth Israel Deaconess Medical Center
      • Boston, Massachusetts, Forenede Stater, 02215
        • Dana-Farber Cancer Institute
      • Boston, Massachusetts, Forenede Stater, 02111
        • Tufts Medical Center
      • Boston, Massachusetts, Forenede Stater, 02118
        • Boston Medical Center
      • Gloucester, Massachusetts, Forenede Stater, 01930
        • Addison Gilbert Hospital
      • Lowell, Massachusetts, Forenede Stater, 01854
        • Lowell General Hospital
      • Milford, Massachusetts, Forenede Stater, 01757
        • Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
      • Newton, Massachusetts, Forenede Stater, 02462
        • Newton-Wellesley Hospital
      • Pittsfield, Massachusetts, Forenede Stater, 01201
        • Berkshire Medical Center - Cancer Center
      • South Weymouth, Massachusetts, Forenede Stater, 02190
        • Dana-Farber/Brigham and Women's Cancer Center at South Shore
      • Springfield, Massachusetts, Forenede Stater, 01199
        • Baystate Medical Center
    • Michigan
      • Adrian, Michigan, Forenede Stater, 49221
        • Hickman Cancer Center
      • Ann Arbor, Michigan, Forenede Stater, 48109
        • University of Michigan Comprehensive Cancer Center
      • Ann Arbor, Michigan, Forenede Stater, 48106
        • Saint Joseph Mercy Hospital
      • Battle Creek, Michigan, Forenede Stater, 49017
        • Bronson Battle Creek
      • Bay City, Michigan, Forenede Stater, 48706
        • McLaren Cancer Institute-Bay City
      • Bloomfield, Michigan, Forenede Stater, 48302
        • McLaren Cancer Institute-Bloomfield
      • Brighton, Michigan, Forenede Stater, 48114
        • Saint Joseph Mercy Brighton
      • Brighton, Michigan, Forenede Stater, 48114
        • IHA Hematology Oncology Consultants-Brighton
      • Brownstown, Michigan, Forenede Stater, 48183
        • Henry Ford Cancer Institute-Downriver
      • Canton, Michigan, Forenede Stater, 48188
        • Saint Joseph Mercy Canton
      • Canton, Michigan, Forenede Stater, 48188
        • IHA Hematology Oncology Consultants-Canton
      • Caro, Michigan, Forenede Stater, 48723
        • Caro Cancer Center
      • Chelsea, Michigan, Forenede Stater, 48118
        • Saint Joseph Mercy Chelsea
      • Chelsea, Michigan, Forenede Stater, 48118
        • IHA Hematology Oncology Consultants-Chelsea
      • Clarkston, Michigan, Forenede Stater, 48346
        • McLaren Cancer Institute-Clarkston
      • Clarkston, Michigan, Forenede Stater, 48346
        • Hematology Oncology Consultants-Clarkston
      • Clarkston, Michigan, Forenede Stater, 48346
        • Newland Medical Associates-Clarkston
      • Clinton Township, Michigan, Forenede Stater, 48038
        • Henry Ford Macomb Hospital-Clinton Township
      • Dearborn, Michigan, Forenede Stater, 48126
        • Henry Ford Medical Center-Fairlane
      • Dearborn, Michigan, Forenede Stater, 48124
        • Beaumont Hospital ? Dearborn
      • Detroit, Michigan, Forenede Stater, 48202
        • Henry Ford Hospital
      • Detroit, Michigan, Forenede Stater, 48201
        • Wayne State University/Karmanos Cancer Institute
      • Detroit, Michigan, Forenede Stater, 48236
        • Ascension Saint John Hospital
      • East China, Michigan, Forenede Stater, 48054
        • Great Lakes Cancer Management Specialists-Doctors Park
      • Escanaba, Michigan, Forenede Stater, 49829
        • Green Bay Oncology - Escanaba
      • Farmington Hills, Michigan, Forenede Stater, 48334
        • Weisberg Cancer Treatment Center
      • Farmington Hills, Michigan, Forenede Stater, 48336
        • Beaumont Hospital - Farmington Hills
      • Flint, Michigan, Forenede Stater, 48532
        • McLaren Cancer Institute-Flint
      • Flint, Michigan, Forenede Stater, 48532
        • Singh and Arora Hematology Oncology PC
      • Flint, Michigan, Forenede Stater, 48503
        • Hurley Medical Center
      • Flint, Michigan, Forenede Stater, 48503
        • Genesee Cancer and Blood Disease Treatment Center
      • Flint, Michigan, Forenede Stater, 48503
        • Genesee Hematology Oncology PC
      • Flint, Michigan, Forenede Stater, 48503
        • Genesys Hurley Cancer Institute
      • Grand Rapids, Michigan, Forenede Stater, 49503
        • Spectrum Health at Butterworth Campus
      • Grand Rapids, Michigan, Forenede Stater, 49503
        • Helen DeVos Children's Hospital at Spectrum Health
      • Grand Rapids, Michigan, Forenede Stater, 49503
        • Mercy Health Saint Mary's
      • Grosse Pointe, Michigan, Forenede Stater, 48230
        • William Beaumont Hospital-Grosse Point
      • Grosse Pointe Woods, Michigan, Forenede Stater, 48236
        • Academic Hematology Oncology Specialists
      • Grosse Pointe Woods, Michigan, Forenede Stater, 48236
        • Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
      • Grosse Pointe Woods, Michigan, Forenede Stater, 48236
        • Michigan Breast Specialists-Grosse Pointe Woods
      • Jackson, Michigan, Forenede Stater, 49201
        • Allegiance Health
      • Kalamazoo, Michigan, Forenede Stater, 49007
        • West Michigan Cancer Center
      • Kalamazoo, Michigan, Forenede Stater, 49007
        • Bronson Methodist Hospital
      • Kalamazoo, Michigan, Forenede Stater, 49048
        • Borgess Medical Center
      • Lansing, Michigan, Forenede Stater, 48912
        • Sparrow Hospital
      • Lansing, Michigan, Forenede Stater, 48910
        • McLaren-Greater Lansing
      • Lansing, Michigan, Forenede Stater, 48912
        • Mid-Michigan Physicians-Lansing
      • Lapeer, Michigan, Forenede Stater, 48446
        • McLaren Cancer Institute-Lapeer Region
      • Livonia, Michigan, Forenede Stater, 48154
        • Saint Mary Mercy Hospital
      • Livonia, Michigan, Forenede Stater, 48154
        • Hope Cancer Clinic
      • Macomb, Michigan, Forenede Stater, 48044
        • Great Lakes Cancer Management Specialists-Macomb Medical Campus
      • Macomb, Michigan, Forenede Stater, 48044
        • Michigan Breast Specialists-Macomb Township
      • Marlette, Michigan, Forenede Stater, 48453
        • Saint Mary's Oncology/Hematology Associates of Marlette
      • Marquette, Michigan, Forenede Stater, 49855
        • UP Health System Marquette
      • Marquette, Michigan, Forenede Stater, 49855
        • UP Health System Hematology Oncology Marquette
      • Midland, Michigan, Forenede Stater, 48670
        • Mid-Michigan Medical Center - Midland
      • Monroe, Michigan, Forenede Stater, 48162
        • Monroe Cancer Center
      • Mount Clemens, Michigan, Forenede Stater, 48043
        • McLaren Cancer Institute-Macomb
      • Mount Pleasant, Michigan, Forenede Stater, 48858
        • McLaren Cancer Institute-Central Michigan
      • Muskegon, Michigan, Forenede Stater, 49444
        • Mercy Health Mercy Campus
      • Niles, Michigan, Forenede Stater, 49120
        • Lakeland Hospital Niles
      • Novi, Michigan, Forenede Stater, 48374
        • Ascension Providence Hospitals - Novi
      • Novi, Michigan, Forenede Stater, 48377
        • Henry Ford Medical Center-Columbus
      • Petoskey, Michigan, Forenede Stater, 49770
        • McLaren Cancer Institute-Northern Michigan
      • Pontiac, Michigan, Forenede Stater, 48341
        • Saint Joseph Mercy Oakland
      • Pontiac, Michigan, Forenede Stater, 48341
        • 21st Century Oncology-Pontiac
      • Pontiac, Michigan, Forenede Stater, 48341
        • Hope Cancer Center
      • Pontiac, Michigan, Forenede Stater, 48341
        • Newland Medical Associates-Pontiac
      • Port Huron, Michigan, Forenede Stater, 48060
        • McLaren-Port Huron
      • Port Huron, Michigan, Forenede Stater, 48060
        • Lake Huron Medical Center
      • Reed City, Michigan, Forenede Stater, 49677
        • Spectrum Health Reed City Hospital
      • Rochester Hills, Michigan, Forenede Stater, 48309
        • Great Lakes Cancer Management Specialists-Rochester Hills
      • Roseville, Michigan, Forenede Stater, 48066
        • Michigan Cancer Specialists
      • Royal Oak, Michigan, Forenede Stater, 48073
        • William Beaumont Hospital-Royal Oak
      • Royal Oak, Michigan, Forenede Stater, 48067
        • Oakland Colon and Rectal Association
      • Royal Oak, Michigan, Forenede Stater, 48073
        • Cancer Care Associates PC
      • Royal Oak, Michigan, Forenede Stater, 48073
        • Comprehensive Medical Center PLLC
      • Royal Oak, Michigan, Forenede Stater, 48073
        • Hematology Oncology Consultants PC
      • Royal Oak, Michigan, Forenede Stater, 48073
        • Oakland Medical Group
      • Saginaw, Michigan, Forenede Stater, 48601
        • Ascension Saint Mary's Hospital
      • Saginaw, Michigan, Forenede Stater, 48604
        • Oncology Hematology Associates of Saginaw Valley PC
      • Saint Joseph, Michigan, Forenede Stater, 49085
        • Lakeland Medical Center Saint Joseph
      • Saint Joseph, Michigan, Forenede Stater, 49085
        • Marie Yeager Cancer Center
      • Southfield, Michigan, Forenede Stater, 48075
        • Ascension Providence Hospitals - Southfield
      • Sterling Heights, Michigan, Forenede Stater, 48312
        • Bhadresh Nayak MD PC-Sterling Heights
      • Sterling Heights, Michigan, Forenede Stater, 48312
        • Premier Hematology Oncology Care
      • Sterling Heights, Michigan, Forenede Stater, 48314
        • Mitchell Folbe MD PC
      • Traverse City, Michigan, Forenede Stater, 49684
        • Munson Medical Center
      • Troy, Michigan, Forenede Stater, 48085
        • William Beaumont Hospital - Troy
      • Troy, Michigan, Forenede Stater, 48084
        • Michigan Institute of Urology-Town Center
      • Troy, Michigan, Forenede Stater, 48085
        • Claudia BR Herke MD PC
      • Troy, Michigan, Forenede Stater, 48098
        • Hematology Oncology Consultants PC-Troy
      • Warren, Michigan, Forenede Stater, 48093
        • Saint John Macomb-Oakland Hospital
      • Warren, Michigan, Forenede Stater, 48088
        • Advanced Breast Care Center PLLC
      • Warren, Michigan, Forenede Stater, 48093
        • Great Lakes Cancer Management Specialists-Macomb Professional Building
      • Warren, Michigan, Forenede Stater, 48093
        • Macomb Hematology Oncology PC
      • Warren, Michigan, Forenede Stater, 48093
        • Michigan Breast Specialists-Warren
      • West Bloomfield, Michigan, Forenede Stater, 48322
        • Henry Ford West Bloomfield Hospital
      • West Branch, Michigan, Forenede Stater, 48661
        • Saint Mary's Oncology/Hematology Associates of West Branch
      • Wyoming, Michigan, Forenede Stater, 49519
        • Metro Health Hospital
      • Ypsilanti, Michigan, Forenede Stater, 48106
        • Huron Gastroenterology PC
      • Ypsilanti, Michigan, Forenede Stater, 48197
        • IHA Hematology Oncology Consultants-Ann Arbor
    • Minnesota
      • Bemidji, Minnesota, Forenede Stater, 56601
        • Sanford Joe Lueken Cancer Center
      • Brainerd, Minnesota, Forenede Stater, 56401
        • Essentia Health Saint Joseph's Medical Center
      • Burnsville, Minnesota, Forenede Stater, 55337
        • Fairview Ridges Hospital
      • Coon Rapids, Minnesota, Forenede Stater, 55433
        • Mercy Hospital
      • Deer River, Minnesota, Forenede Stater, 56636
        • Essentia Health - Deer River Clinic
      • Detroit Lakes, Minnesota, Forenede Stater, 56501
        • Essentia Health Saint Mary's - Detroit Lakes Clinic
      • Duluth, Minnesota, Forenede Stater, 55805
        • Essentia Health Cancer Center
      • Duluth, Minnesota, Forenede Stater, 55805
        • Essentia Health Saint Mary's Medical Center
      • Duluth, Minnesota, Forenede Stater, 55805
        • Miller-Dwan Hospital
      • Edina, Minnesota, Forenede Stater, 55435
        • Fairview-Southdale Hospital
      • Fergus Falls, Minnesota, Forenede Stater, 56537
        • Lake Region Healthcare Corporation-Cancer Care
      • Fosston, Minnesota, Forenede Stater, 56542
        • Essentia Health - Fosston
      • Fridley, Minnesota, Forenede Stater, 55432
        • Unity Hospital
      • Hibbing, Minnesota, Forenede Stater, 55746
        • Essentia Health Hibbing Clinic
      • Maple Grove, Minnesota, Forenede Stater, 55369
        • Fairview Maple Grove Medical Center
      • Maplewood, Minnesota, Forenede Stater, 55109
        • Saint John's Hospital - Healtheast
      • Maplewood, Minnesota, Forenede Stater, 55109
        • Minnesota Oncology Hematology PA-Maplewood
      • Minneapolis, Minnesota, Forenede Stater, 55415
        • Hennepin County Medical Center
      • Minneapolis, Minnesota, Forenede Stater, 55407
        • Abbott-Northwestern Hospital
      • Minneapolis, Minnesota, Forenede Stater, 55454
        • Health Partners Inc
      • Monticello, Minnesota, Forenede Stater, 55362
        • Monticello Cancer Center
      • New Ulm, Minnesota, Forenede Stater, 56073
        • New Ulm Medical Center
      • Park Rapids, Minnesota, Forenede Stater, 56470
        • Essentia Health - Park Rapids
      • Robbinsdale, Minnesota, Forenede Stater, 55422
        • North Memorial Medical Health Center
      • Saint Cloud, Minnesota, Forenede Stater, 56303
        • Coborn Cancer Center at Saint Cloud Hospital
      • Saint Louis Park, Minnesota, Forenede Stater, 55416
        • Park Nicollet Clinic - Saint Louis Park
      • Saint Paul, Minnesota, Forenede Stater, 55101
        • Regions Hospital
      • Saint Paul, Minnesota, Forenede Stater, 55102
        • United Hospital
      • Sandstone, Minnesota, Forenede Stater, 55072
        • Essentia Health Sandstone
      • Shakopee, Minnesota, Forenede Stater, 55379
        • Saint Francis Regional Medical Center
      • Stillwater, Minnesota, Forenede Stater, 55082
        • Lakeview Hospital
      • Virginia, Minnesota, Forenede Stater, 55792
        • Essentia Health Virginia Clinic
      • Waconia, Minnesota, Forenede Stater, 55387
        • Ridgeview Medical Center
      • Willmar, Minnesota, Forenede Stater, 56201
        • Rice Memorial Hospital
      • Woodbury, Minnesota, Forenede Stater, 55125
        • Minnesota Oncology Hematology PA-Woodbury
      • Wyoming, Minnesota, Forenede Stater, 55092
        • Fairview Lakes Medical Center
    • Mississippi
      • Gulfport, Mississippi, Forenede Stater, 39502
        • Gulfport Memorial Hospital
      • Jackson, Mississippi, Forenede Stater, 39216
        • University of Mississippi Medical Center
      • Oxford, Mississippi, Forenede Stater, 38655
        • Baptist Memorial Hospital and Cancer Center-Oxford
      • Pascagoula, Mississippi, Forenede Stater, 39581
        • Singing River Hospital
      • Southhaven, Mississippi, Forenede Stater, 38671
        • Baptist Memorial Hospital and Cancer Center-Desoto
    • Missouri
      • Ballwin, Missouri, Forenede Stater, 63011
        • Saint Louis Cancer and Breast Institute-Ballwin
      • Bolivar, Missouri, Forenede Stater, 65613
        • Central Care Cancer Center - Bolivar
      • Bonne Terre, Missouri, Forenede Stater, 63628
        • Parkland Health Center-Bonne Terre
      • Branson, Missouri, Forenede Stater, 65616
        • Cox Cancer Center Branson
      • Cape Girardeau, Missouri, Forenede Stater, 63703
        • Saint Francis Medical Center
      • Cape Girardeau, Missouri, Forenede Stater, 63703
        • Southeast Cancer Center
      • Chesterfield, Missouri, Forenede Stater, 63017
        • Saint Luke's Hospital
      • City of Saint Peters, Missouri, Forenede Stater, 63376
        • Siteman Cancer Center at Saint Peters Hospital
      • Columbia, Missouri, Forenede Stater, 65212
        • University of Missouri - Ellis Fischel
      • Creve Coeur, Missouri, Forenede Stater, 63141
        • Siteman Cancer Center at West County Hospital
      • Independence, Missouri, Forenede Stater, 64057
        • Centerpoint Medical Center LLC
      • Jefferson City, Missouri, Forenede Stater, 65109
        • Capital Region Southwest Campus
      • Joplin, Missouri, Forenede Stater, 64804
        • Freeman Health System
      • Joplin, Missouri, Forenede Stater, 64804
        • Mercy Hospital Joplin
      • Kansas City, Missouri, Forenede Stater, 64111
        • Saint Luke's Hospital of Kansas City
      • Kansas City, Missouri, Forenede Stater, 64132
        • Research Medical Center
      • Kansas City, Missouri, Forenede Stater, 64118
        • Heartland Hematology and Oncology Associates Incorporated
      • Lee's Summit, Missouri, Forenede Stater, 64086
        • Saint Luke's East - Lee's Summit
      • Liberty, Missouri, Forenede Stater, 64068
        • Liberty Radiation Oncology Center
      • Rolla, Missouri, Forenede Stater, 65401
        • Delbert Day Cancer Institute at PCRMC
      • Rolla, Missouri, Forenede Stater, 65401
        • Mercy Clinic-Rolla-Cancer and Hematology
      • Saint Joseph, Missouri, Forenede Stater, 64507
        • Heartland Regional Medical Center
      • Sainte Genevieve, Missouri, Forenede Stater, 63670
        • Sainte Genevieve County Memorial Hospital
      • Springfield, Missouri, Forenede Stater, 65807
        • CoxHealth South Hospital
      • Springfield, Missouri, Forenede Stater, 65804
        • Mercy Hospital Springfield
      • St Louis, Missouri, Forenede Stater, 63110
        • Washington University School of Medicine
      • St Louis, Missouri, Forenede Stater, 63136
        • Siteman Cancer Center at Christian Hospital
      • St Louis, Missouri, Forenede Stater, 63131
        • Missouri Baptist Medical Center
      • St Louis, Missouri, Forenede Stater, 63141
        • Mercy Hospital Saint Louis
      • St Louis, Missouri, Forenede Stater, 63128
        • Mercy Hospital South
      • St Louis, Missouri, Forenede Stater, 63109
        • Saint Louis Cancer and Breast Institute-South City
      • Sullivan, Missouri, Forenede Stater, 63080
        • Missouri Baptist Sullivan Hospital
      • Sunset Hills, Missouri, Forenede Stater, 63127
        • Missouri Baptist Outpatient Center-Sunset Hills
    • Montana
      • Anaconda, Montana, Forenede Stater, 59711
        • Community Hospital of Anaconda
      • Billings, Montana, Forenede Stater, 59101
        • Billings Clinic Cancer Center
      • Billings, Montana, Forenede Stater, 59101
        • Saint Vincent Healthcare
      • Bozeman, Montana, Forenede Stater, 59715
        • Bozeman Deaconess Hospital
      • Butte, Montana, Forenede Stater, 59701
        • Saint James Community Hospital and Cancer Treatment Center
      • Great Falls, Montana, Forenede Stater, 59405
        • Great Falls Clinic
      • Great Falls, Montana, Forenede Stater, 59405
        • Benefis Healthcare- Sletten Cancer Institute
      • Helena, Montana, Forenede Stater, 59601
        • Saint Peter's Community Hospital
      • Kalispell, Montana, Forenede Stater, 59901
        • Kalispell Regional Medical Center
      • Missoula, Montana, Forenede Stater, 59804
        • Community Medical Hospital
      • Missoula, Montana, Forenede Stater, 59802
        • Saint Patrick Hospital - Community Hospital
    • Nebraska
      • Grand Island, Nebraska, Forenede Stater, 68803
        • CHI Health Saint Francis
      • Kearney, Nebraska, Forenede Stater, 68847
        • CHI Health Good Samaritan
      • Kearney, Nebraska, Forenede Stater, 68845
        • Heartland Hematology and Oncology
      • Lincoln, Nebraska, Forenede Stater, 68506
        • Nebraska Hematology and Oncology
      • Lincoln, Nebraska, Forenede Stater, 68510
        • Nebraska Cancer Research Center
      • Lincoln, Nebraska, Forenede Stater, 68510
        • Saint Elizabeth Regional Medical Center
      • Lincoln, Nebraska, Forenede Stater, 68510
        • Southeast Nebraska Cancer Center
      • Norfolk, Nebraska, Forenede Stater, 68701
        • Faith Regional Health Services Carson Cancer Center
      • North Platte, Nebraska, Forenede Stater, 69101
        • Great Plains Health Callahan Cancer Center
      • Omaha, Nebraska, Forenede Stater, 68114
        • Nebraska Methodist Hospital
      • Omaha, Nebraska, Forenede Stater, 68124
        • Alegent Health Bergan Mercy Medical Center
      • Omaha, Nebraska, Forenede Stater, 68122
        • Alegent Health Immanuel Medical Center
      • Omaha, Nebraska, Forenede Stater, 68130
        • Alegent Health Lakeside Hospital
      • Omaha, Nebraska, Forenede Stater, 68131
        • Creighton University Medical Center
      • Omaha, Nebraska, Forenede Stater, 68124
        • Nebraska Cancer Specialists - Omaha
      • Omaha, Nebraska, Forenede Stater, 68130
        • Oncology Hematology West PC
      • Omaha, Nebraska, Forenede Stater, 68122
        • Hematology and Oncology Consultants PC
      • Papillion, Nebraska, Forenede Stater, 68046
        • Midlands Community Hospital
      • Scottsbluff, Nebraska, Forenede Stater, 69361
        • Regional West Medical Center Cancer Center
    • Nevada
      • Carson City, Nevada, Forenede Stater, 89703
        • Carson Tahoe Regional Medical Center
      • Henderson, Nevada, Forenede Stater, 89052
        • Comprehensive Cancer Centers of Nevada - Henderson
      • Henderson, Nevada, Forenede Stater, 89052
        • OptumCare Cancer Care at Seven Hills
      • Henderson, Nevada, Forenede Stater, 89052
        • Cancer and Blood Specialists-Henderson
      • Henderson, Nevada, Forenede Stater, 89052
        • Las Vegas Cancer Center-Henderson
      • Henderson, Nevada, Forenede Stater, 89074
        • Comprehensive Cancer Centers of Nevada-Southeast Henderson
      • Henderson, Nevada, Forenede Stater, 89074
        • 21st Century Oncology-Henderson
      • Las Vegas, Nevada, Forenede Stater, 89144
        • Summerlin Hospital Medical Center
      • Las Vegas, Nevada, Forenede Stater, 89106
        • Radiation Oncology Centers of Nevada Central
      • Las Vegas, Nevada, Forenede Stater, 89119
        • Radiation Oncology Centers of Nevada Southeast
      • Las Vegas, Nevada, Forenede Stater, 89128
        • Comprehensive Cancer Centers of Nevada - Northwest
      • Las Vegas, Nevada, Forenede Stater, 89128
        • OptumCare Cancer Care at MountainView
      • Las Vegas, Nevada, Forenede Stater, 89135
        • Alliance for Childhood Diseases/Cure 4 the Kids Foundation
      • Las Vegas, Nevada, Forenede Stater, 89144
        • Comprehensive Cancer Centers of Nevada-Summerlin
      • Las Vegas, Nevada, Forenede Stater, 89148
        • Comprehensive Cancer Centers of Nevada
      • Las Vegas, Nevada, Forenede Stater, 89148
        • OptumCare Cancer Care at Fort Apache
      • Las Vegas, Nevada, Forenede Stater, 89169
        • Comprehensive Cancer Centers of Nevada - Central Valley
      • Las Vegas, Nevada, Forenede Stater, 89102
        • University Medical Center of Southern Nevada
      • Las Vegas, Nevada, Forenede Stater, 89106
        • Cancer and Blood Specialists-Shadow
      • Las Vegas, Nevada, Forenede Stater, 89109
        • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
      • Las Vegas, Nevada, Forenede Stater, 89113
        • HealthCare Partners Medical Group Oncology/Hematology-San Martin
      • Las Vegas, Nevada, Forenede Stater, 89121
        • Cancer Therapy and Integrative Medicine
      • Las Vegas, Nevada, Forenede Stater, 89128
        • Cancer and Blood Specialists-Tenaya
      • Las Vegas, Nevada, Forenede Stater, 89128
        • HealthCare Partners Medical Group Oncology/Hematology-Tenaya
      • Las Vegas, Nevada, Forenede Stater, 89148-2405
        • Las Vegas Cancer Center-Medical Center
      • Las Vegas, Nevada, Forenede Stater, 89149
        • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
      • Las Vegas, Nevada, Forenede Stater, 89109
        • 21st Century Oncology
      • Las Vegas, Nevada, Forenede Stater, 89128
        • 21st Century Oncology-Vegas Tenaya
      • Las Vegas, Nevada, Forenede Stater, 89148
        • 21st Century Oncology-Fort Apache
      • Las Vegas, Nevada, Forenede Stater, 89128
        • Ann M Wierman MD LTD
      • Las Vegas, Nevada, Forenede Stater, 89169
        • University Cancer Center
      • Las Vegas, Nevada, Forenede Stater, 89106
        • OptumCare Cancer Care at Oakey
      • Reno, Nevada, Forenede Stater, 89502
        • Renown Regional Medical Center
      • Reno, Nevada, Forenede Stater, 89503
        • Saint Mary's Regional Medical Center
      • Reno, Nevada, Forenede Stater, 89509
        • Radiation Oncology Associates
    • New Hampshire
      • Exeter, New Hampshire, Forenede Stater, 03833
        • Exeter Hospital
      • Nashua, New Hampshire, Forenede Stater, 03060
        • Saint Joseph Hospital
    • New Jersey
      • Brick, New Jersey, Forenede Stater, 08724
        • Ocean Medical Center
      • Cape May Court House, New Jersey, Forenede Stater, 08210
        • AtlantiCare Health Park-Cape May Court House
      • Egg Harbor, New Jersey, Forenede Stater, 08234
        • AtlantiCare Surgery Center
      • Elizabeth, New Jersey, Forenede Stater, 07207
        • Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus
      • Englewood, New Jersey, Forenede Stater, 07631
        • Englewood Hospital and Medical Center
      • Hackensack, New Jersey, Forenede Stater, 07601
        • Hackensack University Medical Center
      • Hamilton, New Jersey, Forenede Stater, 08690
        • The Cancer Institute of New Jersey Hamilton
      • Lakewood, New Jersey, Forenede Stater, 08701
        • Monmouth Medical Center Southern Campus
      • Livingston, New Jersey, Forenede Stater, 07039
        • Saint Barnabas Medical Center
      • Long Branch, New Jersey, Forenede Stater, 07740
        • Monmouth Medical Center
      • Morristown, New Jersey, Forenede Stater, 07960
        • Morristown Medical Center
      • Mount Holly, New Jersey, Forenede Stater, 08060
        • Virtua Memorial
      • Neptune City, New Jersey, Forenede Stater, 07753
        • Jersey Shore Medical Center
      • New Brunswick, New Jersey, Forenede Stater, 08903
        • Rutgers Cancer Institute of New Jersey
      • New Brunswick, New Jersey, Forenede Stater, 08901
        • Saint Peter's University Hospital
      • Newark, New Jersey, Forenede Stater, 07112
        • Newark Beth Israel Medical Center
      • Paterson, New Jersey, Forenede Stater, 07503
        • Saint Joseph's Regional Medical Center
      • Pennington, New Jersey, Forenede Stater, 08534
        • Capital Health Medical Center-Hopewell
      • Red Bank, New Jersey, Forenede Stater, 07701
        • Riverview Medical Center/Booker Cancer Center
      • Somerville, New Jersey, Forenede Stater, 08876
        • Robert Wood Johnson University Hospital Somerset
      • Sparta, New Jersey, Forenede Stater, 07871
        • Sparta Cancer Treatment Center
      • Summit, New Jersey, Forenede Stater, 07902
        • Overlook Hospital
      • Teaneck, New Jersey, Forenede Stater, 07666
        • Holy Name Hospital
      • Toms River, New Jersey, Forenede Stater, 08755
        • Community Medical Center
      • Vineland, New Jersey, Forenede Stater, 08360
        • Inspira Medical Center Vineland
      • Voorhees Township, New Jersey, Forenede Stater, 08043
        • Virtua Voorhees
      • Woodbury, New Jersey, Forenede Stater, 08096
        • Inspira Medical Center Woodbury
    • New York
      • Brooklyn, New York, Forenede Stater, 11203
        • State University of New York Downstate Medical Center
      • Buffalo, New York, Forenede Stater, 14263
        • Roswell Park Cancer Institute
      • Cooperstown, New York, Forenede Stater, 13326
        • Mary Imogene Bassett Hospital
      • East Syracuse, New York, Forenede Stater, 13057
        • Hematology Oncology Associates of Central New York-East Syracuse
      • Elmira, New York, Forenede Stater, 14905
        • Arnot Ogden Medical Center/Falck Cancer Center
      • Glens Falls, New York, Forenede Stater, 12801
        • Glens Falls Hospital
      • Middletown, New York, Forenede Stater, 10940
        • Orange Regional Medical Center
      • Mineola, New York, Forenede Stater, 11501
        • NYU Winthrop Hospital
      • New York, New York, Forenede Stater, 10019
        • Mount Sinai West
      • New York, New York, Forenede Stater, 10029
        • Mount Sinai Hospital
      • New York, New York, Forenede Stater, 10003
        • Mount Sinai Union Square
      • Plattsburgh, New York, Forenede Stater, 12901
        • Champlain Valley Physicians Hospital Medical Center
      • Rochester, New York, Forenede Stater, 14642
        • University of Rochester
      • Rochester, New York, Forenede Stater, 14620
        • Highland Hospital
      • Rochester, New York, Forenede Stater, 14621
        • Rochester General Hospital
      • Staten Island, New York, Forenede Stater, 10305
        • Staten Island University Hospital
      • Stony Brook, New York, Forenede Stater, 11794
        • Stony Brook University Medical Center
      • Syracuse, New York, Forenede Stater, 13210
        • State University of New York Upstate Medical University
      • Syracuse, New York, Forenede Stater, 13215
        • SUNY Upstate Medical Center-Community Campus
      • The Bronx, New York, Forenede Stater, 10461
        • Montefiore Medical Center-Einstein Campus
      • The Bronx, New York, Forenede Stater, 10467
        • Montefiore Medical Center - Moses Campus
      • The Bronx, New York, Forenede Stater, 10451
        • Lincoln Medical and Mental Health Center
      • The Bronx, New York, Forenede Stater, 10461
        • Montefiore Medical Center-Weiler Hospital
      • White Plains, New York, Forenede Stater, 10601
        • Dickstein Cancer Treatment Center
    • North Carolina
      • Albemarle, North Carolina, Forenede Stater, 28002
        • Atrium Health Stanly/LCI-Albemarle
      • Asheboro, North Carolina, Forenede Stater, 27203
        • Randolph Hospital
      • Asheville, North Carolina, Forenede Stater, 28816
        • Hope Women's Cancer Centers-Asheville
      • Asheville, North Carolina, Forenede Stater, 28801
        • Cancer Care of Western North Carolina
      • Asheville, North Carolina, Forenede Stater, 28801
        • Mission Hospital Inc-Memorial Campus
      • Asheville, North Carolina, Forenede Stater, 28803
        • AdventHealth Infusion Center Asheville
      • Burlington, North Carolina, Forenede Stater, 27215
        • Cone Health Cancer Center at Alamance Regional
      • Cary, North Carolina, Forenede Stater, 27518
        • Waverly Hematology Oncology
      • Cary, North Carolina, Forenede Stater, 27518
        • Rex Hematology Oncology Associates-Cary
      • Chapel Hill, North Carolina, Forenede Stater, 27599
        • UNC Lineberger Comprehensive Cancer Center
      • Charlotte, North Carolina, Forenede Stater, 28203
        • Carolinas Medical Center/Levine Cancer Institute
      • Charlotte, North Carolina, Forenede Stater, 28204
        • Novant Health Presbyterian Medical Center
      • Charlotte, North Carolina, Forenede Stater, 28210
        • Atrium Health Pineville/LCI-Pineville
      • Charlotte, North Carolina, Forenede Stater, 28262
        • Atrium Health University City/LCI-University
      • Charlotte, North Carolina, Forenede Stater, 28207
        • Oncology Specialists of Charlotte
      • Charlotte, North Carolina, Forenede Stater, 28262
        • Southern Oncology Specialists-Charlotte
      • Charlotte, North Carolina, Forenede Stater, 28211
        • Levine Cancer Institute-SouthPark
      • Charlotte, North Carolina, Forenede Stater, 28277
        • Levine Cancer Institute-Ballantyne
      • Charlotte, North Carolina, Forenede Stater, 28203
        • Levine Cancer Institute-Tryon
      • Clinton, North Carolina, Forenede Stater, 28328
        • Southeastern Medical Oncology Center-Clinton
      • Concord, North Carolina, Forenede Stater, 28025
        • Atrium Health Cabarrus/LCI-Concord
      • Forest City, North Carolina, Forenede Stater, 28043
        • Levine Cancer Institute - Rutherford
      • Garner, North Carolina, Forenede Stater, 27529
        • Rex Hematology Oncology Associates-Garner
      • Goldsboro, North Carolina, Forenede Stater, 27534
        • Southeastern Medical Oncology Center-Goldsboro
      • Goldsboro, North Carolina, Forenede Stater, 27534
        • Wayne Memorial Hospital
      • Greensboro, North Carolina, Forenede Stater, 27403
        • Cone Health Cancer Center
      • Greenville, North Carolina, Forenede Stater, 27834
        • East Carolina University
      • Hendersonville, North Carolina, Forenede Stater, 28791
        • Hendersonville Hematology and Oncology at Pardee
      • Hendersonville, North Carolina, Forenede Stater, 28791
        • Margaret R Pardee Memorial Hospital
      • Hendersonville, North Carolina, Forenede Stater, 28792
        • AdventHealth Hendersonville
      • Huntersville, North Carolina, Forenede Stater, 28078
        • Southern Oncology Specialists-Huntersville
      • Huntersville, North Carolina, Forenede Stater, 28078
        • Lake Norman Hematology Oncology Specialists-Huntersville
      • Jacksonville, North Carolina, Forenede Stater, 28546
        • Southeastern Medical Oncology Center-Jacksonville
      • Jacksonville, North Carolina, Forenede Stater, 28546
        • Onslow Memorial Hospital
      • Kenansville, North Carolina, Forenede Stater, 28349
        • Vidant Oncology-Kenansville
      • Kinston, North Carolina, Forenede Stater, 28501
        • Vidant Oncology-Kinston
      • Lincolnton, North Carolina, Forenede Stater, 28092
        • Atrium Health Lincoln/LCI-Lincolnton
      • Matthews, North Carolina, Forenede Stater, 28105
        • Novant Health Cancer Specialists-Matthews
      • Matthews, North Carolina, Forenede Stater, 28105
        • Matthews Radiation Oncology Center
      • Mebane, North Carolina, Forenede Stater, 27302
        • Cone Heath Cancer Center at Mebane
      • Monroe, North Carolina, Forenede Stater, 28112
        • Atrium Health Union/LCI-Union
      • Mooresville, North Carolina, Forenede Stater, 28117
        • Lake Norman Hematology Oncology Specialists-Mooresville
      • Pinehurst, North Carolina, Forenede Stater, 28374
        • FirstHealth of the Carolinas-Moore Regional Hospital
      • Raleigh, North Carolina, Forenede Stater, 27607
        • Rex Cancer Center
      • Raleigh, North Carolina, Forenede Stater, 27607
        • Rex Hematology Oncology Associates-Blue Ridge
      • Raleigh, North Carolina, Forenede Stater, 27614
        • Rex Cancer Center of Wakefield
      • Reidsville, North Carolina, Forenede Stater, 27320
        • Annie Penn Memorial Hospital
      • Richlands, North Carolina, Forenede Stater, 28574
        • Vidant Oncology-Richlands
      • Shelby, North Carolina, Forenede Stater, 28150
        • Atrium Health Cleveland/LCI-Cleveland
      • Washington, North Carolina, Forenede Stater, 27889
        • Marion L Shepard Cancer Center at Vidant Beaufort Hospital
      • Winston-Salem, North Carolina, Forenede Stater, 27157
        • Wake Forest University Health Sciences
    • North Dakota
      • Bismarck, North Dakota, Forenede Stater, 58501
        • Sanford Bismarck Medical Center
      • Fargo, North Dakota, Forenede Stater, 58122
        • Sanford Roger Maris Cancer Center
      • Fargo, North Dakota, Forenede Stater, 58103
        • Essentia Health Cancer Center-South University Clinic
      • Fargo, North Dakota, Forenede Stater, 58122
        • Sanford Broadway Medical Center
      • Fargo, North Dakota, Forenede Stater, 58122
        • Sanford Clinic North-Fargo
      • Grand Forks, North Dakota, Forenede Stater, 58201
        • Altru Cancer Center
      • Jamestown, North Dakota, Forenede Stater, 58401
        • Essentia Health - Jamestown Clinic
      • Minot, North Dakota, Forenede Stater, 58701
        • Trinity Cancer Care Center
    • Ohio
      • Akron, Ohio, Forenede Stater, 44307
        • Cleveland Clinic Akron General
      • Beachwood, Ohio, Forenede Stater, 44122
        • UHHS-Chagrin Highlands Medical Center
      • Beachwood, Ohio, Forenede Stater, 44122
        • Cleveland Clinic Cancer Center Beachwood
      • Beavercreek, Ohio, Forenede Stater, 45431
        • Indu and Raj Soin Medical Center
      • Belpre, Ohio, Forenede Stater, 45714
        • Strecker Cancer Center-Belpre
      • Canton, Ohio, Forenede Stater, 44710
        • Aultman Health Foundation
      • Canton, Ohio, Forenede Stater, 44708
        • Mercy Medical Center
      • Centerville, Ohio, Forenede Stater, 45459
        • Miami Valley Hospital South
      • Centerville, Ohio, Forenede Stater, 45459
        • Dayton Physicians LLC-Miami Valley South
      • Chardon, Ohio, Forenede Stater, 44024
        • Geauga Hospital
      • Chillicothe, Ohio, Forenede Stater, 45601
        • Adena Regional Medical Center
      • Cincinnati, Ohio, Forenede Stater, 45219
        • The Christ Hospital
      • Cincinnati, Ohio, Forenede Stater, 45220
        • Good Samaritan Hospital - Cincinnati
      • Cincinnati, Ohio, Forenede Stater, 45242
        • Bethesda North Hospital
      • Cincinnati, Ohio, Forenede Stater, 45242
        • Oncology Hematology Care Inc-Blue Ash
      • Cincinnati, Ohio, Forenede Stater, 45202
        • Oncology Hematology Care Inc-Eden Park
      • Cincinnati, Ohio, Forenede Stater, 45211
        • Oncology Hematology Care Inc-Mercy West
      • Cincinnati, Ohio, Forenede Stater, 45236
        • Oncology Hematology Care Inc-Kenwood
      • Cincinnati, Ohio, Forenede Stater, 45219
        • University of Cincinnati/Barrett Cancer Center
      • Cincinnati, Ohio, Forenede Stater, 45230
        • Oncology Hematology Care Inc - Anderson
      • Cincinnati, Ohio, Forenede Stater, 45247
        • TriHealth Cancer Institute-Westside
      • Cincinnati, Ohio, Forenede Stater, 45255
        • TriHealth Cancer Institute-Anderson
      • Cleveland, Ohio, Forenede Stater, 44106
        • Case Western Reserve University
      • Cleveland, Ohio, Forenede Stater, 44109
        • MetroHealth Medical Center
      • Cleveland, Ohio, Forenede Stater, 44195
        • Cleveland Clinic Foundation
      • Cleveland, Ohio, Forenede Stater, 44111
        • Cleveland Clinic Cancer Center/Fairview Hospital
      • Columbus, Ohio, Forenede Stater, 43214
        • Riverside Methodist Hospital
      • Columbus, Ohio, Forenede Stater, 43210
        • Ohio State University Comprehensive Cancer Center
      • Columbus, Ohio, Forenede Stater, 43219
        • The Mark H Zangmeister Center
      • Columbus, Ohio, Forenede Stater, 43214
        • Columbus Oncology and Hematology Associates Inc
      • Columbus, Ohio, Forenede Stater, 43228
        • Doctors Hospital
      • Columbus, Ohio, Forenede Stater, 43213
        • Mount Carmel East Hospital
      • Columbus, Ohio, Forenede Stater, 43215
        • Grant Medical Center
      • Columbus, Ohio, Forenede Stater, 43222
        • Mount Carmel Health Center West
      • Dayton, Ohio, Forenede Stater, 45406
        • Good Samaritan Hospital - Dayton
      • Dayton, Ohio, Forenede Stater, 45409
        • Miami Valley Hospital
      • Dayton, Ohio, Forenede Stater, 45415
        • Dayton Physician LLC-Miami Valley Hospital North
      • Dayton, Ohio, Forenede Stater, 45415
        • Miami Valley Hospital North
      • Delaware, Ohio, Forenede Stater, 43015
        • Delaware Health Center-Grady Cancer Center
      • Delaware, Ohio, Forenede Stater, 43015
        • Delaware Radiation Oncology
      • Delaware, Ohio, Forenede Stater, 43015
        • Grady Memorial Hospital
      • Dublin, Ohio, Forenede Stater, 43016
        • Dublin Methodist Hospital
      • Elyria, Ohio, Forenede Stater, 44035
        • Mercy Cancer Center-Elyria
      • Fairfield, Ohio, Forenede Stater, 45014
        • Oncology Hematology Care Inc-Healthplex
      • Findlay, Ohio, Forenede Stater, 45840
        • Blanchard Valley Hospital
      • Findlay, Ohio, Forenede Stater, 45840
        • Armes Family Cancer Center
      • Findlay, Ohio, Forenede Stater, 45840
        • Orion Cancer Care
      • Franklin, Ohio, Forenede Stater, 45005-1066
        • Atrium Medical Center-Middletown Regional Hospital
      • Franklin, Ohio, Forenede Stater, 45005
        • Dayton Physicians LLC-Atrium
      • Greenville, Ohio, Forenede Stater, 45331
        • Wayne Hospital
      • Greenville, Ohio, Forenede Stater, 45331
        • Dayton Physicians LLC-Wayne
      • Independence, Ohio, Forenede Stater, 44131
        • Cleveland Clinic Cancer Center Independence
      • Kettering, Ohio, Forenede Stater, 45429
        • Kettering Medical Center
      • Kettering, Ohio, Forenede Stater, 45409
        • Greater Dayton Cancer Center
      • Kettering, Ohio, Forenede Stater, 45420
        • First Dayton Cancer Care
      • Lancaster, Ohio, Forenede Stater, 43130
        • Fairfield Medical Center
      • Mansfield, Ohio, Forenede Stater, 44906
        • Cleveland Clinic Cancer Center Mansfield
      • Mansfield, Ohio, Forenede Stater, 44903
        • OhioHealth Mansfield Hospital
      • Marietta, Ohio, Forenede Stater, 45750
        • Marietta Memorial Hospital
      • Marion, Ohio, Forenede Stater, 43302
        • OhioHealth Marion General Hospital
      • Maumee, Ohio, Forenede Stater, 43537
        • Toledo Clinic Cancer Centers-Maumee
      • Maumee, Ohio, Forenede Stater, 43537
        • Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
      • Mayfield Heights, Ohio, Forenede Stater, 44124
        • Hillcrest Hospital Cancer Center
      • Mayfield Heights, Ohio, Forenede Stater, 44124
        • UH Seidman Cancer Center at Landerbrook Health Center
      • Mentor, Ohio, Forenede Stater, 44060
        • UH Seidman Cancer Center at Lake Health Mentor Campus
      • Middleburg Heights, Ohio, Forenede Stater, 44130
        • UH Seidman Cancer Center at Southwest General Hospital
      • Middletown, Ohio, Forenede Stater, 45042
        • Dayton Physicians LLC-Signal Point
      • Mount Vernon, Ohio, Forenede Stater, 43050
        • Knox Community Hospital
      • Newark, Ohio, Forenede Stater, 43055
        • Licking Memorial Hospital
      • Newark, Ohio, Forenede Stater, 43055
        • Newark Radiation Oncology
      • Oregon, Ohio, Forenede Stater, 43616
        • Saint Charles Hospital
      • Parma, Ohio, Forenede Stater, 44129
        • University Hospitals Parma Medical Center
      • Portsmouth, Ohio, Forenede Stater, 45662
        • Southern Ohio Medical Center
      • Ravenna, Ohio, Forenede Stater, 44266
        • University Hospitals Portage Medical Center
      • Sandusky, Ohio, Forenede Stater, 44870
        • North Coast Cancer Care
      • Sandusky, Ohio, Forenede Stater, 44870
        • UH Seidman Cancer Center at Firelands Regional Medical Center
      • Sidney, Ohio, Forenede Stater, 45365
        • Dayton Physicians LLC-Wilson
      • Springfield, Ohio, Forenede Stater, 45505
        • Springfield Regional Medical Center
      • Springfield, Ohio, Forenede Stater, 45504
        • Springfield Regional Cancer Center
      • Strongsville, Ohio, Forenede Stater, 44136
        • Cleveland Clinic Cancer Center Strongsville
      • Sylvania, Ohio, Forenede Stater, 43560
        • ProMedica Flower Hospital
      • Toledo, Ohio, Forenede Stater, 43623
        • Toledo Clinic Cancer Centers-Toledo
      • Toledo, Ohio, Forenede Stater, 43614
        • University of Toledo
      • Toledo, Ohio, Forenede Stater, 43606
        • The Toledo Hospital/Toledo Children's Hospital
      • Toledo, Ohio, Forenede Stater, 43623
        • Mercy Saint Anne Hospital
      • Troy, Ohio, Forenede Stater, 45373
        • Upper Valley Medical Center
      • Troy, Ohio, Forenede Stater, 45373
        • Dayton Physicians LLC-Upper Valley
      • Wadsworth, Ohio, Forenede Stater, 44281
        • University Hospitals Sharon Health Center
      • Warrensville Heights, Ohio, Forenede Stater, 44122
        • South Pointe Hospital
      • West Chester, Ohio, Forenede Stater, 45069
        • University Pointe
      • Westerville, Ohio, Forenede Stater, 43081
        • Saint Ann's Hospital
      • Westlake, Ohio, Forenede Stater, 44145
        • UH Seidman Cancer Center at Saint John Medical Center
      • Westlake, Ohio, Forenede Stater, 44145
        • UHHS-Westlake Medical Center
      • Wooster, Ohio, Forenede Stater, 44691
        • Cleveland Clinic Wooster Family Health and Surgery Center
      • Zanesville, Ohio, Forenede Stater, 43701
        • Genesis Healthcare System Cancer Care Center
    • Oklahoma
      • Lawton, Oklahoma, Forenede Stater, 73505
        • Cancer Centers of Southwest Oklahoma Research
      • Oklahoma City, Oklahoma, Forenede Stater, 73104
        • University of Oklahoma Health Sciences Center
      • Oklahoma City, Oklahoma, Forenede Stater, 73120
        • Mercy Hospital Oklahoma City
      • Oklahoma City, Oklahoma, Forenede Stater, 73109
        • Integris Southwest Medical Center
      • Oklahoma City, Oklahoma, Forenede Stater, 73142
        • Integris Cancer Institute of Oklahoma
      • Tulsa, Oklahoma, Forenede Stater, 74146
        • Oklahoma Cancer Specialists and Research Institute-Tulsa
    • Oregon
      • Baker City, Oregon, Forenede Stater, 97814
        • Saint Alphonsus Medical Center-Baker City
      • Bend, Oregon, Forenede Stater, 97701
        • Saint Charles Health System
      • Clackamas, Oregon, Forenede Stater, 97015
        • Clackamas Radiation Oncology Center
      • Clackamas, Oregon, Forenede Stater, 97015
        • Providence Oncology and Hematology Care Southeast
      • Coos Bay, Oregon, Forenede Stater, 97420
        • Bay Area Hospital
      • Corvallis, Oregon, Forenede Stater, 97330
        • Good Samaritan Hospital
      • Eugene, Oregon, Forenede Stater, 97401
        • Willamette Valley Cancer Center
      • Grants Pass, Oregon, Forenede Stater, 97527
        • Three Rivers Community Hospital
      • Medford, Oregon, Forenede Stater, 97504
        • Providence Medford Medical Center
      • Medford, Oregon, Forenede Stater, 97504
        • Rogue Valley Medical Center
      • Newberg, Oregon, Forenede Stater, 97132
        • Providence Newberg Medical Center
      • Ontario, Oregon, Forenede Stater, 97914
        • Saint Alphonsus Medical Center-Ontario
      • Oregon City, Oregon, Forenede Stater, 97045
        • Providence Willamette Falls Medical Center
      • Portland, Oregon, Forenede Stater, 97213
        • Providence Portland Medical Center
      • Portland, Oregon, Forenede Stater, 97225
        • Providence Saint Vincent Medical Center
      • Portland, Oregon, Forenede Stater, 97227
        • Kaiser Permanente Northwest
      • Portland, Oregon, Forenede Stater, 97227
        • Compass Oncology Rose Quarter
      • Portland, Oregon, Forenede Stater, 97213
        • Compass Oncology East
      • Portland, Oregon, Forenede Stater, 97225
        • Compass Oncology West
      • Tualatin, Oregon, Forenede Stater, 97062
        • Compass Oncology Tualatin
    • Pennsylvania
      • Abington, Pennsylvania, Forenede Stater, 19001
        • Abington Memorial Hospital
      • Allentown, Pennsylvania, Forenede Stater, 18103
        • Lehigh Valley Hospital-Cedar Crest
      • Beaver, Pennsylvania, Forenede Stater, 15009
        • UPMC-Heritage Valley Health System Beaver
      • Bethlehem, Pennsylvania, Forenede Stater, 18017
        • Lehigh Valley Hospital - Muhlenberg
      • Bryn Mawr, Pennsylvania, Forenede Stater, 19010
        • Bryn Mawr Hospital
      • Chadds Ford, Pennsylvania, Forenede Stater, 19317
        • Christiana Care Health System-Concord Health Center
      • Danville, Pennsylvania, Forenede Stater, 17822
        • Geisinger Medical Center
      • Darby, Pennsylvania, Forenede Stater, 19023-1291
        • Mercy Fitzgerald Hospital
      • Doylestown, Pennsylvania, Forenede Stater, 18901
        • Doylestown Hospital
      • East Stroudsburg, Pennsylvania, Forenede Stater, 18301
        • Pocono Medical Center
      • Ephrata, Pennsylvania, Forenede Stater, 17522
        • Ephrata Cancer Center
      • Gettysburg, Pennsylvania, Forenede Stater, 17325
        • Adams Cancer Center
      • Greensburg, Pennsylvania, Forenede Stater, 15601
        • UPMC Cancer Centers - Arnold Palmer Pavilion
      • Hanover, Pennsylvania, Forenede Stater, 17331
        • Cherry Tree Cancer Center
      • Harrisburg, Pennsylvania, Forenede Stater, 17109
        • UPMC Pinnacle Cancer Center/Community Osteopathic Campus
      • Hazleton, Pennsylvania, Forenede Stater, 18201
        • Geisinger Medical Center-Cancer Center Hazleton
      • Hershey, Pennsylvania, Forenede Stater, 17033-0850
        • Penn State Milton S Hershey Medical Center
      • Jefferson Hills, Pennsylvania, Forenede Stater, 15025
        • Jefferson Hospital
      • Johnstown, Pennsylvania, Forenede Stater, 15901
        • UPMC-Johnstown/John P. Murtha Regional Cancer Center
      • Kittanning, Pennsylvania, Forenede Stater, 16201
        • Armstrong Center for Medicine and Health
      • Lancaster, Pennsylvania, Forenede Stater, 17604
        • Lancaster General Hospital
      • Langhorne, Pennsylvania, Forenede Stater, 19047
        • Saint Mary Medical and Regional Cancer Center
      • Lebanon, Pennsylvania, Forenede Stater, 17042
        • Sechler Family Cancer Center
      • Lewisburg, Pennsylvania, Forenede Stater, 17837
        • Geisinger Medical Oncology-Lewisburg
      • Lewistown, Pennsylvania, Forenede Stater, 17044
        • Lewistown Hospital
      • McKeesport, Pennsylvania, Forenede Stater, 15132
        • UPMC Cancer Center at UPMC McKeesport
      • Media, Pennsylvania, Forenede Stater, 19063
        • Riddle Memorial Hospital
      • Monroeville, Pennsylvania, Forenede Stater, 15146
        • Forbes Hospital
      • Moon Township, Pennsylvania, Forenede Stater, 15108
        • UPMC-Coraopolis/Heritage Valley Radiation Oncology
      • Natrona Heights, Pennsylvania, Forenede Stater, 15065
        • Allegheny Valley Hospital
      • Norristown, Pennsylvania, Forenede Stater, 19401
        • Suburban Community Hospital and Cancer Center
      • Paoli, Pennsylvania, Forenede Stater, 19301
        • Paoli Memorial Hospital
      • Philadelphia, Pennsylvania, Forenede Stater, 19111
        • Fox Chase Cancer Center
      • Philadelphia, Pennsylvania, Forenede Stater, 19107
        • Thomas Jefferson University Hospital
      • Philadelphia, Pennsylvania, Forenede Stater, 19140
        • Temple University Hospital
      • Philadelphia, Pennsylvania, Forenede Stater, 19141
        • Einstein Medical Center Philadelphia
      • Philadelphia, Pennsylvania, Forenede Stater, 19124
        • Eastern Regional Medical Center
      • Philadelphia, Pennsylvania, Forenede Stater, 19114
        • Aria Health-Torresdale Campus
      • Phoenixville, Pennsylvania, Forenede Stater, 19460
        • Phoenixville Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15212
        • Allegheny General Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15224
        • West Penn Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15213
        • UPMC-Magee Womens Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15232
        • University of Pittsburgh Cancer Institute (UPCI)
      • Pittsburgh, Pennsylvania, Forenede Stater, 15232
        • UPMC-Shadyside Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15213
        • UPMC-Presbyterian Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15215
        • UPMC-Saint Margaret
      • Pittsburgh, Pennsylvania, Forenede Stater, 15236
        • UPMC Jefferson Regional Radiation Oncology
      • Pittsburgh, Pennsylvania, Forenede Stater, 15237
        • UPMC-Passavant Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15243
        • UPMC-Saint Clair Hospital Cancer Center
      • Pottsville, Pennsylvania, Forenede Stater, 17901
        • Geisinger Cancer Services-Pottsville
      • Reading, Pennsylvania, Forenede Stater, 19605
        • Penn State Health Saint Joseph Medical Center
      • Sayre, Pennsylvania, Forenede Stater, 18840
        • Guthrie Medical Group PC-Robert Packer Hospital
      • Scranton, Pennsylvania, Forenede Stater, 18510
        • Community Medical Center
      • Scranton, Pennsylvania, Forenede Stater, 18508
        • Hematology and Oncology Associates of North East Pennsylvania
      • Selinsgrove, Pennsylvania, Forenede Stater, 17870
        • Geisinger Medical Oncology-Selinsgrove
      • Sellersville, Pennsylvania, Forenede Stater, 18960
        • Grand View Hospital
      • Seneca, Pennsylvania, Forenede Stater, 16346
        • UPMC Cancer Center at UPMC Northwest
      • State College, Pennsylvania, Forenede Stater, 16801
        • Geisinger Medical Group
      • State College, Pennsylvania, Forenede Stater, 16803
        • Mount Nittany Medical Center
      • Uniontown, Pennsylvania, Forenede Stater, 15401
        • UPMC Uniontown Hospital Radiation Oncology
      • Washington, Pennsylvania, Forenede Stater, 15301
        • UPMC Washington Hospital Radiation Oncology
      • West Chester, Pennsylvania, Forenede Stater, 19380
        • Chester County Hospital
      • West Grove, Pennsylvania, Forenede Stater, 19390
        • Jennersville Regional Hospital
      • West Reading, Pennsylvania, Forenede Stater, 19611
        • Reading Hospital
      • Wexford, Pennsylvania, Forenede Stater, 15090
        • Wexford Health and Wellness Pavilion
      • Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
        • Geisinger Wyoming Valley/Henry Cancer Center
      • Williamsport, Pennsylvania, Forenede Stater, 17701
        • UPMC Susquehanna
      • Wynnewood, Pennsylvania, Forenede Stater, 19096
        • Lankenau Medical Center
      • York, Pennsylvania, Forenede Stater, 17403
        • WellSpan Health-York Cancer Center
      • York, Pennsylvania, Forenede Stater, 17403
        • WellSpan Health-York Hospital
    • South Carolina
      • Anderson, South Carolina, Forenede Stater, 29621
        • AnMed Health Cancer Center
      • Charleston, South Carolina, Forenede Stater, 29425
        • Medical University of South Carolina
      • Easley, South Carolina, Forenede Stater, 29640
        • Greenville Health System Cancer Institute-Easley
      • Florence, South Carolina, Forenede Stater, 29506
        • McLeod Regional Medical Center
      • Gaffney, South Carolina, Forenede Stater, 29341
        • Gibbs Cancer Center-Gaffney
      • Georgetown, South Carolina, Forenede Stater, 29440
        • Tidelands Georgetown Memorial Hospital
      • Greenville, South Carolina, Forenede Stater, 29607
        • Saint Francis Cancer Center
      • Greenville, South Carolina, Forenede Stater, 29601
        • Saint Francis Hospital
      • Greenville, South Carolina, Forenede Stater, 29601
        • Greenville Health System Cancer Institute-Andrews
      • Greenville, South Carolina, Forenede Stater, 29605
        • Greenville Health System Cancer Institute-Faris
      • Greenville, South Carolina, Forenede Stater, 29605
        • Greenville Memorial Hospital
      • Greenville, South Carolina, Forenede Stater, 29615
        • Greenville Health System Cancer Institute-Eastside
      • Greenville, South Carolina, Forenede Stater, 29605
        • Greenville Health System Cancer Institute-Butternut
      • Greenwood, South Carolina, Forenede Stater, 29646
        • Self Regional Healthcare
      • Greer, South Carolina, Forenede Stater, 29651
        • Gibbs Cancer Center-Pelham
      • Greer, South Carolina, Forenede Stater, 29650
        • Greenville Health System Cancer Institute-Greer
      • Hilton Head Island, South Carolina, Forenede Stater, 29926-3827
        • South Carolina Cancer Specialists PC
      • Rock Hill, South Carolina, Forenede Stater, 29732
        • Levine Cancer Institute-Rock Hill
      • Seneca, South Carolina, Forenede Stater, 29672
        • Greenville Health System Cancer Institute-Seneca
      • Spartanburg, South Carolina, Forenede Stater, 29303
        • Spartanburg Medical Center
      • Spartanburg, South Carolina, Forenede Stater, 29307
        • Greenville Health System Cancer Institute-Spartanburg
      • Union, South Carolina, Forenede Stater, 29379
        • MGC Hematology Oncology-Union
    • South Dakota
      • Rapid City, South Dakota, Forenede Stater, 57701
        • Rapid City Regional Hospital
      • Sioux Falls, South Dakota, Forenede Stater, 57117-5134
        • Sanford USD Medical Center - Sioux Falls
      • Sioux Falls, South Dakota, Forenede Stater, 57104
        • Sanford Cancer Center Oncology Clinic
    • Tennessee
      • Bristol, Tennessee, Forenede Stater, 37620
        • Wellmont Medical Associates Oncology and Hematology-Bristol
      • Bristol, Tennessee, Forenede Stater, 37620
        • Wellmont Bristol Regional Medical Center
      • Chattanooga, Tennessee, Forenede Stater, 37404
        • Memorial Hospital
      • Hixson, Tennessee, Forenede Stater, 37343
        • Pulmonary Medicine Center of Chattanooga-Hixson
      • Johnson City, Tennessee, Forenede Stater, 37604
        • Wellmont Medical Associates Oncology and Hematology-Johnson City
      • Kingsport, Tennessee, Forenede Stater, 37660
        • Wellmont Holston Valley Hospital and Medical Center
      • Kingsport, Tennessee, Forenede Stater, 37660
        • Regional Cancer Center at Indian Path Community Hospital
      • Knoxville, Tennessee, Forenede Stater, 37916
        • Thompson Cancer Survival Center
      • Knoxville, Tennessee, Forenede Stater, 37920
        • University of Tennessee - Knoxville
      • Memphis, Tennessee, Forenede Stater, 38120
        • Baptist Memorial Hospital and Cancer Center-Memphis
      • Nashville, Tennessee, Forenede Stater, 37208
        • Meharry Medical College
      • Ooltewah, Tennessee, Forenede Stater, 37363
        • Memorial GYN Plus
    • Texas
      • Abilene, Texas, Forenede Stater, 79601
        • Hendrick Medical Center
      • Abilene, Texas, Forenede Stater, 79606
        • Texas Cancer Center
      • Amarillo, Texas, Forenede Stater, 79106
        • Texas Oncology PA - Amarillo
      • Austin, Texas, Forenede Stater, 78701
        • Dell Seton Medical Center at The University of Texas
      • Austin, Texas, Forenede Stater, 78705
        • Texas Oncology-Austin Midtown
      • Austin, Texas, Forenede Stater, 78731
        • Texas Oncology - Central Austin Cancer Center
      • Austin, Texas, Forenede Stater, 78745
        • Texas Oncology - South Austin Cancer Center
      • Bedford, Texas, Forenede Stater, 76022
        • Texas Oncology Bedford
      • Bryan, Texas, Forenede Stater, 77802
        • Saint Joseph Regional Cancer Center
      • Dallas, Texas, Forenede Stater, 75230
        • Texas Cancer Center - Medical City Dallas
      • Dallas, Texas, Forenede Stater, 75231
        • Texas Health Presbyterian Hospital Dallas
      • Denton, Texas, Forenede Stater, 76210
        • Texas Oncology-Denton South
      • El Paso, Texas, Forenede Stater, 79905
        • Texas Tech University Health Sciences Center-El Paso
      • El Paso, Texas, Forenede Stater, 79915
        • Texas Oncology-El Paso
      • Flower Mound, Texas, Forenede Stater, 75028
        • Texas Oncology-Flower Mound
      • Fort Worth, Texas, Forenede Stater, 76104
        • Texas Oncology - Fort Worth Cancer Center
      • Galveston, Texas, Forenede Stater, 77555-0565
        • University of Texas Medical Branch
      • Garland, Texas, Forenede Stater, 75042
        • Texas Oncology - Garland
      • Grapevine, Texas, Forenede Stater, 76053
        • Texas Oncology-Grapevine
      • Houston, Texas, Forenede Stater, 77030
        • M D Anderson Cancer Center
      • Houston, Texas, Forenede Stater, 77094
        • MD Anderson in Katy
      • Houston, Texas, Forenede Stater, 77030
        • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
      • Houston, Texas, Forenede Stater, 77030
        • Ben Taub General Hospital
      • League City, Texas, Forenede Stater, 77573
        • UTMB Cancer Center at Victory Lakes
      • Longview, Texas, Forenede Stater, 75601
        • Texas Oncology-Longview Cancer Center
      • Lubbock, Texas, Forenede Stater, 79410
        • Covenant Medical Center-Lakeside
      • McAllen, Texas, Forenede Stater, 78503
        • Texas Oncology-McAllen
      • McKinney, Texas, Forenede Stater, 75071
        • Texas Oncology-McKinney
      • Midland, Texas, Forenede Stater, 79701
        • Texas Oncology-Midland Allison Cancer Center
      • Nassau Bay, Texas, Forenede Stater, 77058
        • MD Anderson League City
      • Odessa, Texas, Forenede Stater, 79761
        • West Texas Cancer Center
      • Paris, Texas, Forenede Stater, 75460
        • Texas Oncology-Paris
      • Plano, Texas, Forenede Stater, 75093
        • Texas Oncology-Plano West
      • Plano, Texas, Forenede Stater, 75075
        • North Texas Regional Cancer Center
      • Round Rock, Texas, Forenede Stater, 78681
        • Texas Oncology - Round Rock Cancer Center
      • San Antonio, Texas, Forenede Stater, 78229
        • University Hospital
      • San Antonio, Texas, Forenede Stater, 78229
        • University of Texas Health Science Center at San Antonio
      • San Antonio, Texas, Forenede Stater, 78217
        • Cancer Care Centers of South Texas- Northeast
      • San Antonio, Texas, Forenede Stater, 78229
        • Cancer Therapy and Research Center at The UT Health Science Center at San Antonio
      • Sherman, Texas, Forenede Stater, 75090
        • Texas Cancer Center-Sherman
      • Sugar Land, Texas, Forenede Stater, 77478
        • MD Anderson in Sugar Land
      • Sugar Land, Texas, Forenede Stater, 77479
        • Texas Oncology Cancer Center Sugar Land
      • The Woodlands, Texas, Forenede Stater, 77384
        • MD Anderson in The Woodlands
      • The Woodlands, Texas, Forenede Stater, 77380
        • Texas Oncology-The Woodlands
      • Tyler, Texas, Forenede Stater, 75702
        • Tyler Cancer Center
      • Waco, Texas, Forenede Stater, 76712
        • Texas Oncology-Waco Highway 6
      • Webster, Texas, Forenede Stater, 77598
        • Deke Slayton Cancer Center
      • Wichita Falls, Texas, Forenede Stater, 76310
        • Texas Oncology-Wichita Falls Texoma Cancer Center
    • Utah
      • American Fork, Utah, Forenede Stater, 84003
        • American Fork Hospital / Huntsman Intermountain Cancer Center
      • Cedar City, Utah, Forenede Stater, 84720
        • Sandra L Maxwell Cancer Center
      • Farmington, Utah, Forenede Stater, 84025
        • Farmington Health Center
      • Logan, Utah, Forenede Stater, 84321
        • Logan Regional Hospital
      • Murray, Utah, Forenede Stater, 84107
        • Intermountain Medical Center
      • Ogden, Utah, Forenede Stater, 84403
        • McKay-Dee Hospital Center
      • Provo, Utah, Forenede Stater, 84604
        • Utah Valley Regional Medical Center
      • Riverton, Utah, Forenede Stater, 84065
        • Riverton Hospital
      • Salt Lake City, Utah, Forenede Stater, 84112
        • Huntsman Cancer Institute/University of Utah
      • Salt Lake City, Utah, Forenede Stater, 84106
        • Utah Cancer Specialists-Salt Lake City
      • Salt Lake City, Utah, Forenede Stater, 84143
        • LDS Hospital
      • South Jordan, Utah, Forenede Stater, 84009
        • South Jordan Health Center
      • St. George, Utah, Forenede Stater, 84770
        • Dixie Medical Center Regional Cancer Center
    • Vermont
      • Berlin Corners, Vermont, Forenede Stater, 05602
        • Central Vermont Medical Center/National Life Cancer Treatment
      • Burlington, Vermont, Forenede Stater, 05401
        • University of Vermont Medical Center
      • Burlington, Vermont, Forenede Stater, 05405
        • University of Vermont and State Agricultural College
    • Virginia
      • Bristol, Virginia, Forenede Stater, 24201
        • Wellmont Medical Associates-Bristol
      • Burke, Virginia, Forenede Stater, 22015
        • Kaiser Permanente-Burke Medical Center
      • Charlottesville, Virginia, Forenede Stater, 22901
        • Sentara Martha Jefferson Hospital
      • Fairfax, Virginia, Forenede Stater, 22031
        • Inova Schar Cancer Institute
      • Fairfax, Virginia, Forenede Stater, 22031
        • Virginia Cancer Specialists-Fairfax
      • Falls Church, Virginia, Forenede Stater, 22042
        • Inova Fairfax Hospital
      • Fishersville, Virginia, Forenede Stater, 22939
        • Augusta Health Center for Cancer and Blood Disorders
      • Fredericksburg, Virginia, Forenede Stater, 22408
        • Hematology Oncology Associates of Fredericksburg Inc
      • Gloucester, Virginia, Forenede Stater, 23061
        • Peninsula Cancer Institute-Gloucester
      • Lynchburg, Virginia, Forenede Stater, 24501
        • Centra Lynchburg Hematology-Oncology Clinic Inc
      • McLean, Virginia, Forenede Stater, 22102
        • Kaiser Permanente Tysons Corner Medical Center
      • Mechanicsville, Virginia, Forenede Stater, 23116
        • Bon Secours Memorial Regional Medical Center
      • Midlothian, Virginia, Forenede Stater, 23114
        • Bon Secours Saint Francis Medical Center
      • Newport News, Virginia, Forenede Stater, 23601
        • Peninsula Cancer Institute-Newport News
      • Norton, Virginia, Forenede Stater, 24273
        • Southwest VA Regional Cancer Center
      • Richmond, Virginia, Forenede Stater, 23298
        • Virginia Commonwealth University/Massey Cancer Center
      • Richmond, Virginia, Forenede Stater, 23230
        • Virginia Cancer Institute
      • Richmond, Virginia, Forenede Stater, 23226
        • Bon Secours Saint Mary's Hospital
      • South Hill, Virginia, Forenede Stater, 23970
        • VCU Community Memorial Health Center
      • Virginia Beach, Virginia, Forenede Stater, 23454
        • Peninsula Cancer Institute-Cancer Specialists of Tidewater
      • Williamsburg, Virginia, Forenede Stater, 23185
        • Peninsula Cancer Institute-Williamsburg
      • Winchester, Virginia, Forenede Stater, 22601
        • Shenandoah Oncology PC
    • Washington
      • Aberdeen, Washington, Forenede Stater, 98520
        • Providence Regional Cancer System-Aberdeen
      • Anacortes, Washington, Forenede Stater, 98221
        • Cancer Care Center at Island Hospital
      • Auburn, Washington, Forenede Stater, 98001
        • MultiCare Auburn Medical Center
      • Bainbridge Island, Washington, Forenede Stater, 98110
        • Virginia Mason Bainbridge Island Medical Center
      • Bellevue, Washington, Forenede Stater, 98005
        • Swedish Cancer Institute-Eastside Oncology Hematology
      • Bellevue, Washington, Forenede Stater, 98004
        • Overlake Hospital Medical Center
      • Bellingham, Washington, Forenede Stater, 98225
        • PeaceHealth Saint Joseph Medical Center
      • Bremerton, Washington, Forenede Stater, 98310
        • Harrison HealthPartners Hematology and Oncology-Bremerton
      • Bremerton, Washington, Forenede Stater, 98310
        • Harrison Medical Center
      • Burien, Washington, Forenede Stater, 98166
        • Highline Medical Center-Main Campus
      • Centralia, Washington, Forenede Stater, 98531
        • Providence Regional Cancer System-Centralia
      • Edmonds, Washington, Forenede Stater, 98026
        • Swedish Cancer Institute-Edmonds
      • Enumclaw, Washington, Forenede Stater, 98022
        • Saint Elizabeth Hospital
      • Everett, Washington, Forenede Stater, 98201
        • Providence Regional Cancer Partnership
      • Federal Way, Washington, Forenede Stater, 98002
        • Virginia Mason Federal Way Medical Center
      • Federal Way, Washington, Forenede Stater, 98003
        • Saint Francis Hospital
      • Gig Harbor, Washington, Forenede Stater, 98332
        • Tacoma/Valley Radiation Oncology Centers-Gig Harbor
      • Gig Harbor, Washington, Forenede Stater, 98335
        • MultiCare Gig Harbor Medical Park
      • Issaquah, Washington, Forenede Stater, 98029
        • Swedish Cancer Institute-Issaquah
      • Kennewick, Washington, Forenede Stater, 99336
        • Kadlec Clinic Hematology and Oncology
      • Kennewick, Washington, Forenede Stater, 99336
        • Northwest Cancer Clinic
      • Lacey, Washington, Forenede Stater, 98503
        • Providence Regional Cancer System-Lacey
      • Lakewood, Washington, Forenede Stater, 98499
        • Saint Clare Hospital
      • Longview, Washington, Forenede Stater, 98632
        • PeaceHealth Saint John Medical Center
      • Lynnwood, Washington, Forenede Stater, 98036
        • Virginia Mason Lynnwood Medical Center
      • Port Townsend, Washington, Forenede Stater, 98368
        • Jefferson Healthcare
      • Poulsbo, Washington, Forenede Stater, 98370
        • Harrison HealthPartners Hematology and Oncology-Poulsbo
      • Poulsbo, Washington, Forenede Stater, 98370
        • Peninsula Cancer Center
      • Puyallup, Washington, Forenede Stater, 98372
        • MultiCare Good Samaritan Hospital
      • Puyallup, Washington, Forenede Stater, 98372
        • Tacoma/Valley Radiation Oncology Centers-Puyallup
      • Renton, Washington, Forenede Stater, 98055
        • Valley Medical Center
      • Seattle, Washington, Forenede Stater, 98101
        • Virginia Mason Medical Center
      • Seattle, Washington, Forenede Stater, 98107
        • Swedish Medical Center-Ballard Campus
      • Seattle, Washington, Forenede Stater, 98112
        • Kaiser Permanente Washington
      • Seattle, Washington, Forenede Stater, 98104
        • Minor and James Medical PLLC
      • Seattle, Washington, Forenede Stater, 98104
        • Pacific Gynecology Specialists
      • Seattle, Washington, Forenede Stater, 98122-4307
        • Swedish Medical Center-First Hill
      • Seattle, Washington, Forenede Stater, 98122-5711
        • Swedish Medical Center-Cherry Hill
      • Shelton, Washington, Forenede Stater, 98584
        • Providence Regional Cancer System-Shelton
      • Spokane, Washington, Forenede Stater, 99204
        • Rockwood Cancer Treatment Center-DHEC-Downtown
      • Spokane, Washington, Forenede Stater, 99218
        • Rockwood North Cancer Treatment Center
      • Spokane Valley, Washington, Forenede Stater, 99216
        • Rockwood Clinic Cancer Treatment Center-Valley
      • Tacoma, Washington, Forenede Stater, 98405
        • Northwest Medical Specialties PLLC
      • Tacoma, Washington, Forenede Stater, 98405
        • MultiCare Tacoma General Hospital
      • Tacoma, Washington, Forenede Stater, 98405
        • Tacoma/Valley Radiation Oncology Centers-Saint Joe's
      • Tacoma, Washington, Forenede Stater, 97405
        • Tacoma/Valley Radiation Oncology Centers-Jackson Hall
      • Tacoma, Washington, Forenede Stater, 98405
        • Franciscan Research Center-Northwest Medical Plaza
      • Vancouver, Washington, Forenede Stater, 98664
        • PeaceHealth Southwest Medical Center
      • Vancouver, Washington, Forenede Stater, 98684
        • Compass Oncology Vancouver
      • Walla Walla, Washington, Forenede Stater, 99362
        • Providence Saint Mary Regional Cancer Center
      • Yakima, Washington, Forenede Stater, 98902
        • North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
      • Yelm, Washington, Forenede Stater, 98597
        • Providence Regional Cancer System-Yelm
    • West Virginia
      • Bridgeport, West Virginia, Forenede Stater, 26330
        • United Hospital Center
      • Charleston, West Virginia, Forenede Stater, 25304
        • West Virginia University Charleston Division
      • Huntington, West Virginia, Forenede Stater, 25701
        • Edwards Comprehensive Cancer Center
      • Martinsburg, West Virginia, Forenede Stater, 25401
        • WVUH-Berkely Medical Center
      • Morgantown, West Virginia, Forenede Stater, 26506
        • West Virginia University Healthcare
      • Parkersburg, West Virginia, Forenede Stater, 26101
        • Camden Clark Medical Center
      • Princeton, West Virginia, Forenede Stater, 24740
        • Princeton Community Hospital
    • Wisconsin
      • Antigo, Wisconsin, Forenede Stater, 54409
        • Langlade Hospital and Cancer Center
      • Appleton, Wisconsin, Forenede Stater, 54911
        • Radiology Associates of Appleton/ThedaCare Regional Medical Center
      • Ashland, Wisconsin, Forenede Stater, 54806
        • Duluth Clinic Ashland
      • Ashland, Wisconsin, Forenede Stater, 54806
        • Northwest Wisconsin Cancer Center
      • Brookfield, Wisconsin, Forenede Stater, 53045
        • Wheaton Franciscan Healthcare-Elmbrook Memorial Hospital
      • Burlington, Wisconsin, Forenede Stater, 53105
        • Aurora Cancer Care-Southern Lakes VLCC
      • Chippewa Falls, Wisconsin, Forenede Stater, 54729
        • Marshfield Clinic-Chippewa Center
      • Eau Claire, Wisconsin, Forenede Stater, 54701
        • Marshfield Medical Center-EC Cancer Center
      • Eau Claire, Wisconsin, Forenede Stater, 54701
        • Marshfield Clinic Cancer Center at Sacred Heart
      • Fond du Lac, Wisconsin, Forenede Stater, 54937
        • Aurora Health Center-Fond du Lac
      • Fond du Lac, Wisconsin, Forenede Stater, 54935
        • Saint Agnes Hospital/Agnesian Cancer Center
      • Franklin, Wisconsin, Forenede Stater, 53132
        • Wheaton Franciscan Healthcare-Saint Francis/Reiman Cancer Center
      • Germantown, Wisconsin, Forenede Stater, 53022
        • Aurora Health Care Germantown Health Center
      • Grafton, Wisconsin, Forenede Stater, 53024
        • Aurora Cancer Care-Grafton
      • Green Bay, Wisconsin, Forenede Stater, 54311
        • Aurora BayCare Medical Center
      • Green Bay, Wisconsin, Forenede Stater, 54301
        • Saint Vincent Hospital Cancer Center Green Bay
      • Green Bay, Wisconsin, Forenede Stater, 54303
        • Saint Vincent Hospital Cancer Center at Saint Mary's
      • Green Bay, Wisconsin, Forenede Stater, 54303
        • Green Bay Oncology Limited at Saint Mary's Hospital
      • Green Bay, Wisconsin, Forenede Stater, 54301-3526
        • Green Bay Oncology at Saint Vincent Hospital
      • Janesville, Wisconsin, Forenede Stater, 53547
        • Mercy Health System
      • Kenosha, Wisconsin, Forenede Stater, 53142
        • Aurora Cancer Care-Kenosha South
      • La Crosse, Wisconsin, Forenede Stater, 54601
        • Gundersen Lutheran Medical Center
      • Ladysmith, Wisconsin, Forenede Stater, 54848
        • Marshfield Clinic - Ladysmith Center
      • Manitowoc, Wisconsin, Forenede Stater, 54221
        • Holy Family Memorial Hospital
      • Marinette, Wisconsin, Forenede Stater, 54143
        • Aurora Bay Area Medical Group-Marinette
      • Marinette, Wisconsin, Forenede Stater, 54143
        • Bay Area Medical Center
      • Marshfield, Wisconsin, Forenede Stater, 54449
        • Marshfield Medical Center-Marshfield
      • Mequon, Wisconsin, Forenede Stater, 53097
        • Columbia Saint Mary's Hospital - Ozaukee
      • Milwaukee, Wisconsin, Forenede Stater, 53209
        • Aurora Cancer Care-Milwaukee
      • Milwaukee, Wisconsin, Forenede Stater, 53215
        • Aurora Saint Luke's Medical Center
      • Milwaukee, Wisconsin, Forenede Stater, 53233
        • Aurora Sinai Medical Center
      • Milwaukee, Wisconsin, Forenede Stater, 53211
        • Columbia Saint Mary's Water Tower Medical Commons
      • Minocqua, Wisconsin, Forenede Stater, 54548
        • Marshfield Clinic-Minocqua Center
      • Mukwonago, Wisconsin, Forenede Stater, 53149
        • ProHealth D N Greenwald Center
      • New Richmond, Wisconsin, Forenede Stater, 54017
        • Cancer Center of Western Wisconsin
      • Oconomowoc, Wisconsin, Forenede Stater, 53066
        • ProHealth Oconomowoc Memorial Hospital
      • Oconto Falls, Wisconsin, Forenede Stater, 54154
        • Saint Vincent Hospital Cancer Center at Oconto Falls
      • Oshkosh, Wisconsin, Forenede Stater, 54904
        • Vince Lombardi Cancer Clinic - Oshkosh
      • Racine, Wisconsin, Forenede Stater, 53406
        • Aurora Cancer Care-Racine
      • Racine, Wisconsin, Forenede Stater, 53405
        • Wheaton Franciscan Cancer Care - All Saints
      • Rice Lake, Wisconsin, Forenede Stater, 54868
        • Marshfield Medical Center-Rice Lake
      • Sheboygan, Wisconsin, Forenede Stater, 53081
        • Vince Lombardi Cancer Clinic-Sheboygan
      • Sheboygan, Wisconsin, Forenede Stater, 53081
        • HSHS Saint Nicholas Hospital
      • Stevens Point, Wisconsin, Forenede Stater, 54482
        • Marshfield Clinic Stevens Point Center
      • Stevens Point, Wisconsin, Forenede Stater, 54481
        • Ascension Saint Michael's Hospital
      • Sturgeon Bay, Wisconsin, Forenede Stater, 54235-1495
        • Saint Vincent Hospital Cancer Center at Sturgeon Bay
      • Sturgeon Bay, Wisconsin, Forenede Stater, 54235
        • Green Bay Oncology - Sturgeon Bay
      • Summit, Wisconsin, Forenede Stater, 53066
        • Aurora Medical Center in Summit
      • Two Rivers, Wisconsin, Forenede Stater, 54241
        • Vince Lombardi Cancer Clinic-Two Rivers
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • UW Cancer Center at ProHealth Care
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • ProHealth Waukesha Memorial Hospital
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • Aurora Cancer Care-Waukesha
      • Wausau, Wisconsin, Forenede Stater, 54401
        • Aspirus Regional Cancer Center
      • Wausau, Wisconsin, Forenede Stater, 54401
        • Marshfield Clinic-Wausau Center
      • Wauwatosa, Wisconsin, Forenede Stater, 53226
        • Aurora Cancer Care-Milwaukee West
      • Wauwatosa, Wisconsin, Forenede Stater, 53226
        • Wheaton Franciscan Healthcare-Saint Joseph/Wauwatosa Campus
      • West Allis, Wisconsin, Forenede Stater, 53227
        • Aurora West Allis Medical Center
      • Weston, Wisconsin, Forenede Stater, 54476
        • Marshfield Clinic - Weston Center
      • Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
        • Marshfield Clinic - Wisconsin Rapids Center
      • Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
        • Aspirus UW Cancer Center
    • Wyoming
      • Cheyenne, Wyoming, Forenede Stater, 82001
        • Cheyenne Regional Medical Center-West
      • Cody, Wyoming, Forenede Stater, 82414
        • Big Horn Basin Cancer Center
      • Cody, Wyoming, Forenede Stater, 82414
        • Billings Clinic-Cody
      • Sheridan, Wyoming, Forenede Stater, 82801
        • Welch Cancer Center

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

14 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Beskrivelse

Inklusionskriterier:

  • Patienten skal have underskrevet og dateret en institutionel revisionsnævn (IRB)-godkendt samtykkeformular, der er i overensstemmelse med føderale og institutionelle retningslinjer
  • Eastern Cooperative Oncology Group (ECOG) præstationsstatus på 0 eller 1
  • Tumoren skal være unilateralt invasivt adenokarcinom i brystet ved histologisk undersøgelse

  • Alle følgende iscenesættelseskriterier (ifølge den 7. udgave af American Joint Committee on Cancer [AJCC] Cancer Staging Manual) skal være opfyldt:

    • Ved patologisk evaluering skal primær tumor være pT1-3
    • Ved patologisk evaluering skal ipsilaterale noder være pN0, pN1 (pN1mi, pN1a, pN1b, pN1c), pN2a, pN2b, pN3a eller pN3b
    • Hvis pN0, skal tumor være > 3,0 cm

  • Tumoren skal være blevet bestemt til at være human epidermal vækstfaktor receptor 2 (HER2)-negativ som følger:

    • Immunhistokemi (IHC) 0-1+; eller
    • IHC 2+ og in situ hybridisering (ISH) ikke-amplificeret med et forhold mellem HER2 og centromere enumerator probe 17 (CEP17) < 2,0, og hvis rapporteret, gennemsnitligt HER2 genkopiantal < 4 signaler/celler; eller
    • ISH ikke-amplificeret med et forhold på HER2 til CEP17 < 2,0, og hvis rapporteret, gennemsnitligt HER2-genkopiantal < 4 signaler/celler
  • Tumoren skal være blevet bestemt til at være østrogenreceptor (ER)- og progesteronreceptor (PgR)-negativ vurderet af de nuværende retningslinjer fra American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP); patienter med < 1 % ER- og PgR-farvning med IHC betragtes som negative
  • Patienten skal have gennemgået enten en mastektomi (total, hudbesparende eller brystvortebesparende) eller lumpektomi
  • For patienter, der gennemgår lumpektomi, skal marginerne af den resekerede prøve være histologisk fri for invasiv tumor og ductal carcinoma in situ (DCIS) som bestemt af den lokale patolog; hvis patologisk undersøgelse viser tumor ved resektionslinjen, kan yderligere udskæringer udføres for at opnå klare marginer; hvis tumor stadig er til stede ved den resekerede margin efter re-excision(er), skal patienten gennemgå mastektomi for at være berettiget; (patienter med marginer positive for lobulært karcinom in situ [LCIS] er kvalificerede uden yderligere resektion)
  • For patienter, der gennemgår mastektomi, skal marginerne være fri for resterende grov tumor; (patienter med mikroskopiske positive marginer er berettigede, så længe postmastektomi strålebehandling [RT] af brystvæggen vil blive administreret)

  • Patienten skal have gennemført en af ​​procedurerne til evaluering af patologisk nodalstatus, der er anført nedenfor.

    • Sentinel lymfadenektomi alene:

      • Hvis patologisk nodal stadieinddeling baseret på sentinel lymfadenektomi er pN0 eller pN1b;
      • Hvis patologisk nodal stadieinddeling baseret på sentinel lymfadenektomi er pN1mi eller pN1a, og patienten har gennemgået brystbevarende kirurgi (med planlagt bryststrålebehandling), skal den primære tumor være T1 eller T2 ved patologisk evaluering, og nodale involvering skal begrænses til 1 eller 2 positive noder
    • Sentinel lymfadenektomi efterfulgt af fjernelse af yderligere non-sentinel lymfeknuder, hvis sentinel node (SN) er positiv; eller
    • Aksellymfadenektomi med eller uden SN-isoleringsprocedure
  • Intervallet mellem den sidste operation for brystkræft (inklusive re-excision af marginer) og randomisering må ikke være mere end 60 dage
  • Absolut neutrofiltal (ANC) skal være >= 1200/mm^3
  • Blodpladeantal skal være >= 100.000/mm^3
  • Hæmoglobin skal være >= 10 g/dL
  • Total bilirubin skal være =< øvre normalgrænse (ULN) for laboratoriet (laboratoriet), medmindre patienten har en bilirubinforhøjelse > ULN til 1,5 x ULN på grund af Gilberts sygdom eller lignende syndrom, der involverer langsom konjugering af bilirubin
  • Alkalisk fosfatase skal være =< 2,5 x ULN for laboratoriet

  • Aspartataminotransferase (AST) skal være =< 1,5 x ULN for laboratoriet

    • Bemærk: Hvis alaninaminotransferase (ALT) udføres i stedet for AST (pr. institutions standardpraksis), skal ALT-værdien være =< 1,5 x ULN; hvis begge blev udført, skal AST være =< 1,5 x ULN
  • Patienter med AST eller alkalisk fosfatase > ULN er berettiget til at blive inkluderet i undersøgelsen, hvis leverbilleddannelse (computertomografi [CT], magnetisk resonansbilleddannelse [MRI], positronemissionstomografi [PET]-CT eller PET-scanning) udført inden for 90 dage før til randomisering viser ikke metastatisk sygdom, og kravene ovenfor er opfyldt
  • Patienter med alkalisk fosfatase, der er > ULN, men =< 2,5 x ULN eller uforklarlige knoglesmerter er berettigede til at blive inkluderet i undersøgelsen, hvis en knoglescanning, PET-CT-scanning eller PET-scanning udført inden for 90 dage før randomisering ikke viser metastatisk sygdom
  • Tilstrækkelig nyrefunktion bestemt inden for 6 uger før randomisering defineret som det seneste serumkreatinin =< ULN eller målt eller beregnet kreatininclearance > 60 ml/min.
  • Vurdering af venstre ventrikulær ejektionsfraktion (LVEF) skal udføres inden for 90 dage før randomisering; (LVEF-vurdering udført ved 2-dimensionelt [D] ekkokardiogram foretrækkes; multi-gated acquisition [MUGA] scanning kan dog erstattes baseret på institutionelle præferencer;) LVEF skal være >= 50 % uanset hjertebilleddannelsesfacilitetens nedre grænse på normal

Ekskluderingskriterier:

  • T4-tumorer inklusive inflammatorisk brystkræft
  • definitive kliniske eller radiologiske tegn på metastatisk sygdom; påkrævede billeddiagnostiske undersøgelser skal være udført inden for 90 dage før randomisering
  • Synkron eller tidligere kontralateral invasiv brystkræft; (patienter med synkron og/eller tidligere kontralateral DCIS eller LCIS er berettigede)
  • Enhver tidligere historie med ipsilateral invasiv brystkræft eller ipsilateral DCIS; (patienter med synkron eller tidligere ipsilateral LCIS er berettiget)
  • Anamnese med ikke-brystmaligniteter (bortset fra in situ-kræft, der kun er behandlet med lokal excision og basalcelle- og pladecellekarcinomer i huden) inden for 5 år før randomisering
  • Tidligere behandling med antracykliner eller taxaner for enhver malignitet
  • Kemoterapi administreret for den aktuelt diagnosticerede brystkræft før randomisering
  • Enhver fortsat brug af kønshormonbehandling, f.eks. p-piller, ovariehormonerstatningsterapi; patienter er berettigede, hvis disse lægemidler seponeres før randomisering

  • Hjertesygdom (historie af og/eller aktiv sygdom), der ville udelukke brugen af ​​de lægemidler, der er inkluderet i behandlingsregimerne; dette omfatter, men er ikke begrænset til:

    • Aktiv hjertesygdom

      • Angina pectoris, der kræver den nuværende brug af anti-anginal medicin;
      • Ventrikulære arytmier med undtagelse af benigne præmature ventrikulære kontraktioner;
      • Supraventrikulære og nodale arytmier, der kræver en pacemaker eller ikke kontrolleres med medicin;
      • Ledningsabnormitet, der kræver en pacemaker;
      • Valvulær sygdom med dokumenteret kompromittering af hjertefunktion; eller
      • Symptomatisk perikarditis

    • Anamnese med hjertesygdom

      • Myokardieinfarkt dokumenteret af forhøjede hjerteenzymer eller vedvarende regionale vægabnormiteter ved vurdering af venstre ventrikel (LV) funktion;
      • Anamnese med dokumenteret kongestiv hjertesvigt (CHF); eller
      • Dokumenteret kardiomyopati
  • Ukontrolleret hypertension defineret som vedvarende systolisk blodtryk (BP) > 150 mmHg eller diastolisk BP > 90 mmHg; (patienter med initiale BP-forhøjelser er berettigede, hvis initiering eller justering af BP-medicin sænker trykket for at opfylde adgangskriterierne)
  • Aktiv hepatitis B eller hepatitis C med unormale leverfunktionstests
  • Patienter, der vides at være humane immundefektvirus (HIV) positive med en baseline cluster of differentiation (CD)4-tal på < 250 celler/mm^3 eller har en historie med erhvervet immundefektsyndrom (AIDS) indikatortilstande
  • Iboende lungesygdom, der resulterer i dyspnø
  • Anamnese med hospitalsindlæggelse inden for de seneste 12 måneder for diabetisk ketoacidose (DKA) eller hyperosmolært hyperglykæmisk nonketotisk syndrom (HHNS)
  • Aktiv infektion eller kronisk infektion, der kræver kronisk undertrykkende antibiotika
  • Nervesystemlidelse (paræstesi, perifer motorisk neuropati eller perifer sensorisk neuropati) >= grad 2 ifølge Common Terminology Criteria for Adverse Events (CTCAE) version (v)4.0
  • Forhold, der ville forbyde administration af kortikosteroider
  • Kronisk daglig behandling med kortikosteroider med en dosis på >= 10 mg/dag methylprednisolonækvivalent (eksklusive inhalerede steroider)
  • Kendt overfølsomhed over for et hvilket som helst af undersøgelseslægemidlerne eller hjælpestofferne, f.eks. polysorbat 80 og Cremophor® EL
  • Anden ikke-malign systemisk sygdom, der ville forhindre patienten i at modtage undersøgelsesbehandling eller ville forhindre nødvendig opfølgning
  • Psykiatriske eller vanedannende lidelser eller andre tilstande, der efter investigatorens mening vil forhindre patienten i at opfylde undersøgelseskravene
  • Graviditet eller amning på tidspunktet for studiestart; (bemærk: graviditetstest i henhold til institutionelle standarder for kvinder i den fødedygtige alder skal udføres inden for 2 uger før randomisering)
  • Brug af ethvert forsøgsprodukt inden for 4 uger før randomisering

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Ingen (Åben etiket)

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Aktiv komparator: Arm I (AC-->WP)
Patienterne får doxorubicinhydrochlorid IV over 15 minutter og cyclophosphamid IV over 30 minutter på dag 1. Behandlingen gentages hver 2. uge i 4 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet. Patienterne får derefter paclitaxel IV over 60 minutter på dag 1. Behandlingen gentages ugentligt i 12 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Paclitaxel
Givet IV
Andre navne:
  • Taxol
  • Anzatax
  • Asotax
  • Bristaxol
  • Praxel
  • Taxol Konzentrat
Medicin: Cyclofosfamid
Givet IV
Andre navne:
  • Cytoxan
  • CTX
  • (-)-Cyclophosphamid
  • 2H-1,3,2-Oxazaphosphorin, 2-[bis(2-chlorethyl)amino]tetrahydro-, 2-oxid, monohydrat
  • Carloxan
  • Ciclofosfamida
  • Ciclofosfamid
  • Cicloxal
  • Clafen
  • Claphene
  • CP monohydrat
  • CYCLO-celle
  • Cykloblastin
  • Cycloblastin
  • Cyclofosfam
  • Cyclophosphamid monohydrat
  • Cyclophospamidum
  • Cyclofosfan
  • Cyclophosphanum
  • Cyclostin
  • Cytophosphan
  • Cytofosfan
  • Fosfaseron
  • Genoxal
  • Genuxal
  • Ledoxina
  • Mitoxan
  • Neosar
  • Revimune
  • Syklofosfamid
  • WR- 138719
Medicin: Doxorubicin Hydrochlorid
Givet IV
Andre navne:
  • Adriamycin
  • 5,12-naphthacendion, 10-[(3-amino-2,3,6-trideoxy-alfa-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy -8-(hydroxyacetyl)-1-methoxy-, hydrochlorid, (8S-cis)- (9Cl)
  • ADM
  • Adriacin
  • Adriamycin hydrochlorid
  • Adriamycin PFS
  • Adriamycin RDF
  • ADRIAMYCIN, HYDROCHLORID
  • Adriblastina
  • Adriblastin
  • Adrimedac
  • Chloridrato de Doxorrubicina
  • DOX
  • DOXO-CELL
  • Doxolem
  • Doxorubicin.HCl
  • Doxorubin
  • Farmiblastina
  • FI 106
  • FI-106
  • hydroxydaunorubicin
  • Rubex
Eksperimentel: Arm II (AC-->WP + carboplatin)
Patienterne får doxorubicinhydrochlorid og cyclophosphamid som i arm I. Patienterne får derefter paclitaxel IV over 60 minutter på dag 1, 8 og 15 og carboplatin IV over 30-60 minutter på dag 1. Behandlingen gentages hver 3. uge i 4 forløb i fravær af sygdomsprogression eller uacceptabel toksicitet.
Andet: Laboratoriebiomarkøranalyse
Korrelative undersøgelser
Medicin: Carboplatin
Givet IV
Andre navne:
  • Blastocarb
  • Carboplat
  • Carboplatin Hexal
  • Carboplatino
  • Carbosin
  • Carbosol
  • Carbotec
  • CBDCA
  • Displata
  • Ercar
  • JM-8
  • Nealorin
  • Novoplatin
  • Paraplatin
  • Paraplatin AQ
  • Platinwas
  • Ribocarbo
  • Paraplat
Medicin: Paclitaxel
Givet IV
Andre navne:
  • Taxol
  • Anzatax
  • Asotax
  • Bristaxol
  • Praxel
  • Taxol Konzentrat
Medicin: Cyclofosfamid
Givet IV
Andre navne:
  • Cytoxan
  • CTX
  • (-)-Cyclophosphamid
  • 2H-1,3,2-Oxazaphosphorin, 2-[bis(2-chlorethyl)amino]tetrahydro-, 2-oxid, monohydrat
  • Carloxan
  • Ciclofosfamida
  • Ciclofosfamid
  • Cicloxal
  • Clafen
  • Claphene
  • CP monohydrat
  • CYCLO-celle
  • Cykloblastin
  • Cycloblastin
  • Cyclofosfam
  • Cyclophosphamid monohydrat
  • Cyclophospamidum
  • Cyclofosfan
  • Cyclophosphanum
  • Cyclostin
  • Cytophosphan
  • Cytofosfan
  • Fosfaseron
  • Genoxal
  • Genuxal
  • Ledoxina
  • Mitoxan
  • Neosar
  • Revimune
  • Syklofosfamid
  • WR- 138719
Medicin: Doxorubicin Hydrochlorid
Givet IV
Andre navne:
  • Adriamycin
  • 5,12-naphthacendion, 10-[(3-amino-2,3,6-trideoxy-alfa-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy -8-(hydroxyacetyl)-1-methoxy-, hydrochlorid, (8S-cis)- (9Cl)
  • ADM
  • Adriacin
  • Adriamycin hydrochlorid
  • Adriamycin PFS
  • Adriamycin RDF
  • ADRIAMYCIN, HYDROCHLORID
  • Adriblastina
  • Adriblastin
  • Adrimedac
  • Chloridrato de Doxorrubicina
  • DOX
  • DOXO-CELL
  • Doxolem
  • Doxorubicin.HCl
  • Doxorubin
  • Farmiblastina
  • FI 106
  • FI-106
  • hydroxydaunorubicin
  • Rubex

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
IDFS
Tidsramme: Op til 10 år
IDFS-hændelser er lokalt invasivt recidiv efter mastektomi, lokalt invasivt recidiv i det ipsilaterale bryst efter lumpektomi, regionalt recidiv, fjernt recidiv, kontralateral invasiv brystkræft, anden ikke-bryst primær cancer (eksklusive plade- eller basalcellekarcinom i huden) eller død af enhver årsag før recidiv eller anden primær cancer. IDFS vil blive sammenlignet mellem de to behandlingsarme ved den stratificerede log-rang test. Kaplan-Meier-estimaterne vil blive beregnet separat for patienter under de forskellige behandlingsregimer.
Op til 10 år

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
BCFS
Tidsramme: Fra randomisering til lokalt recidiv (invasivt eller DCIS), regionalt recidiv eller fjernt recidiv, kontralateral brystkræft (invasiv eller DCIS) eller død af enhver årsag, vurderet op til 10 år
De stratificerede log-rank tests vil være 2-sidede med signifikansniveau 0,05. Behandlingseffektivitet i disse sekundære endepunkter vil blive vurderet af Cox-modeller, der justerer for kliniske faktorer såsom alder, antal positive knuder, BRCA-mutationsstatus, tumorstørrelse og tumorgrad.
Fra randomisering til lokalt recidiv (invasivt eller DCIS), regionalt recidiv eller fjernt recidiv, kontralateral brystkræft (invasiv eller DCIS) eller død af enhver årsag, vurderet op til 10 år
DRFI
Tidsramme: Fra randomisering til fjernmetastasering eller død af brystkræft, uanset forekomst af eventuelle mellemliggende lokale eller regionale tilbagefald, kontralaterale brystkræftformer eller ikke-bryst sekundære kræftformer, vurderet op til 10 år
De stratificerede log-rank tests vil være 2-sidede med signifikansniveau 0,05. Behandlingseffektivitet i disse sekundære endepunkter vil blive vurderet af Cox-modeller, der justerer for kliniske faktorer såsom alder, antal positive knuder, BRCA-mutationsstatus, tumorstørrelse og tumorgrad.
Fra randomisering til fjernmetastasering eller død af brystkræft, uanset forekomst af eventuelle mellemliggende lokale eller regionale tilbagefald, kontralaterale brystkræftformer eller ikke-bryst sekundære kræftformer, vurderet op til 10 år
Hyppigheder af uønskede hændelser kategoriseret ved hjælp af National Cancer Institute CTCAE v4.0
Tidsramme: Op til 10 år
Hyppigheder af alle uønskede hændelser i behandlingsperioden vil blive opstillet efter behandling, toksicitetstype og grad. Pearson Chi-squared-testen med kontinuitetsjustering vil blive brugt til at sammenligne toksicitetsgrader i hver type mellem de to behandlingsregimer. Testen vil være 2-sidet med signifikansniveau 0,05.
Op til 10 år
OS
Tidsramme: Fra randomisering til død uanset årsag, vurderet op til 10 år
De stratificerede log-rank tests vil være 2-sidede med signifikansniveau 0,05. Behandlingseffektivitet i disse sekundære endepunkter vil blive vurderet af Cox-modeller, der justerer for kliniske faktorer såsom alder, antal positive knuder, BRCA-mutationsstatus, tumorstørrelse og tumorgrad.
Fra randomisering til død uanset årsag, vurderet op til 10 år
RFI
Tidsramme: Fra randomisering til invasiv lokal, regional eller fjern gentagelse, eller død som følge af brystkræft (censureret for død af andre årsager), vurderet op til 10 år
De stratificerede log-rank tests vil være 2-sidede med signifikansniveau 0,05. Behandlingseffektivitet i disse sekundære endepunkter vil blive vurderet af Cox-modeller, der justerer for kliniske faktorer såsom alder, antal positive knuder, BRCA-mutationsstatus, tumorstørrelse og tumorgrad.
Fra randomisering til invasiv lokal, regional eller fjern gentagelse, eller død som følge af brystkræft (censureret for død af andre årsager), vurderet op til 10 år

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

NRG Oncology

Samarbejdspartnere

National Cancer Institute (NCI)

Efterforskere

  • Ledende efterforsker: Vicente Valero, NRG Oncology

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

26. juli 2015

Primær færdiggørelse (Faktiske)

31. december 2025

Studieafslutning (Anslået)

31. oktober 2026

Datoer for studieregistrering

Først indsendt

30. juni 2015

Først indsendt, der opfyldte QC-kriterier

30. juni 2015

Først opslået (Anslået)

2. juli 2015

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

6. maj 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

5. maj 2026

Sidst verificeret

1. maj 2026

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • NRG-BR003 (Anden identifikator: CTEP)
  • U10CA180868 (U.S. NIH-bevilling/kontrakt)
  • NCI-2015-00128 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
  • NRG-BR1428

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

JA

IPD-planbeskrivelse

NCI is committed to sharing data in accordance with NIH policy. For more details on how clinical trial data is shared, access the link to the NIH data sharing policy page.

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

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