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Effect of Hydrogen-rich Water During Tapering on Recovery After Functional Overreaching in Basketball Players

15. juli 2026 opdateret af: Jakub Krejci, Palacky University

Effect of Hydrogen-rich Water Supplementation During Tapering on Recovery After Functional Overreaching in Competitive Male Basketball Players: A Randomized, Double-blind, Placebo-controlled Paralel-group Trial

The goal of this clinical trial is to evaluate whether hydrogen-rich water supplementation during tapering improves recovery after functional overreaching in competitive male basketball players aged 18-35 years. The main questions it aims to answer are:

  • Does hydrogen-rich water improve autonomic recovery after functional overreaching?
  • Does hydrogen-rich water improve recovery in biochemical, performance, and subjective feeling outcomes during tapering?

Researchers will compare hydrogen-rich water to placebo (water containing no molecular hydrogen) to determine whether molecular hydrogen improves recovery after accumulated fatigue has been induced by functional overreaching. Participants will:

  • Complete a training cycle including normal training, functional overreaching, and tapering.
  • Consume hydrogen-rich or placebo water daily during the one-week tapering period.
  • Undergo repeated testing of autonomic nervous system, blood biochemical markers, performance, and subjective soreness.

Studieoversigt

Status

Ikke rekrutterer endnu

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

The study consists of an initial screening and entry testing phase, followed by one week of normal training, two weeks of functional overreaching, and one week of tapering. During the functional overreaching period, training load is increased to approximately 120-130% of normal training load to induce accumulated fatigue. During the tapering period, training volume is reduced to approximately 50-60% of normal training volume to support recovery and performance rebound.

The molecular hydrogen is administered only during the tapering period. Participants in the experimental group consume 2.5 L per day of hydrogen-rich water. The total daily dose is divided into 0.5 L in the morning, 1.5 L around training, and 0.5 L in the evening. Participants in the placebo group consume visually matched placebo water according to the same total daily intake and timing schedule. Supplementation adherence is monitored using logs, dose counts, and attendance records. Participants are randomly assigned in a 1:1 ratio to either the experimental group or the placebo group. Randomization is performed using a block scheme and a computer random number generator.

Testing is performed at multiple time points: entry laboratory testing, baseline after normal training, post-functional overreaching, and post-taper. The primary interval for evaluation is the change from post-functional overreaching to post-taper. Statistical analysis is based on a t-test or analysis of variance. Data that not follow a normal distribution are treated using a logarithmic transformation or analyzed using nonparametric tests. The significance level is set at 0.05.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

30

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

Undersøgelse Kontakt Backup

Studiesteder

  • Tjekkiet
      • Olomouc, Tjekkiet, 77111
        • Palacky University, Faculty of Physical Culture
        • Kontakt:

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen

Tager imod sunde frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Competitive male basketball players.
  • Signed informed consent.
  • Completion of entry medical and laboratory screening.

Exclusion Criteria:

  • Acute injury or infection.
  • History or presence of relevant cardiovascular, respiratory, metabolic, or other disease that may affect the study results.
  • Use of medication affecting recovery markers or study results.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Grundvidenskab
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Dobbelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Hydrogen-rich water
Hydrogen-rich water administered at a dose of 2.5 L per day during a one-week tapering period.
Kosttilskud: Hydrogen-rich water
Hydrogen-rich water with molecular hydrogen concentration >1.0 ppm.
Andre navne:
  • Tirtan generator (Nutristamina, Ostrava, Czech Republic)
Placebo komparator: Placebo water
Placebo water administered at a dose of 2.5 L per day during a one-week tapering period.
Kosttilskud: Placebo water
Tap water without molecular hydrogen.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
RMSSD
Tidsramme: One-week change between post-overreaching and post-taper.
The root mean square of successive differences of RR intervals (RMSSD) is used as an index of parasympathetic activity and is calculated from an ECG using heart rate variability analysis.
One-week change between post-overreaching and post-taper.

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Creatine kinase
Tidsramme: One-week change between post-overreaching and post-taper.
Blood creatine kinase concentration is used as a marker of muscle damage.
One-week change between post-overreaching and post-taper.
High-sensitivity C-reactive protein
Tidsramme: One-week change between post-overreaching and post-taper.
High-sensitivity C-reactive protein concentration is used as a marker of systemic inflammatory.
One-week change between post-overreaching and post-taper.
Cortisol
Tidsramme: One-week change between post-overreaching and post-taper.
Blood cortisol concentration is used as a marker of physiological stress response.
One-week change between post-overreaching and post-taper.
Testosterone
Tidsramme: One-week change between post-overreaching and post-taper.
Blood testosterone concentration is used as a marker related to anabolic-catabolic balance.
One-week change between post-overreaching and post-taper.
Urea
Tidsramme: One-week change between post-overreaching and post-taper.
Blood urea concentration is used as a marker related to metabolic and protein-turnover stress.
One-week change between post-overreaching and post-taper.
Leukocytes
Tidsramme: One-week change between post-overreaching and post-taper.
Blood leukocyte count is used as a marker of immune-related response to training.
One-week change between post-overreaching and post-taper.
Lymphocytes
Tidsramme: One-week change between post-overreaching and post-taper.
Blood lymphocyte count is used as a marker of immune-related response to training.
One-week change between post-overreaching and post-taper.
Neutrophils
Tidsramme: One-week change between post-overreaching and post-taper.
Blood lymphocyte count is used as a marker of imflammatory response to training.
One-week change between post-overreaching and post-taper.
Reactive strength index
Tidsramme: One-week change between post-overreaching and post-taper.
Reactive strength index is used as an marker of neuromuscular function of the lower limbs and is measured using a drop jump.
One-week change between post-overreaching and post-taper.
Hangrip test
Tidsramme: One-week change between post-overreaching and post-taper.
Handgrip test is used as a marker of forearm muscle strength and is measured using a dynamometer.
One-week change between post-overreaching and post-taper.
20-m sprint
Tidsramme: One-week change between post-overreaching and post-taper.
20-m sprint test is used to assess linear speed.
One-week change between post-overreaching and post-taper.
Repeated sprint
Tidsramme: One-week change between post-overreaching and post-taper.
20 x 15 m repeated sprint test is used to asses repeated sprint ability.
One-week change between post-overreaching and post-taper.
Agility T-test
Tidsramme: One-week change between post-overreaching and post-taper.
Agility T-test is used to assess planned change-of-direction performance.
One-week change between post-overreaching and post-taper.
Basketball jump shot accuracy test
Tidsramme: One-week change between post-overreaching and post-taper.
Basketball jump shot accuracy test is used to assess basketball-specific performance.
One-week change between post-overreaching and post-taper.
Muscle soreness
Tidsramme: One-week change between post-overreaching and post-taper.
Muscle soreness is assessed subjectively using a visual analog scale, which is represented by a 100 mm line marked 0 (no pain) and 100 (worst imaginable pain).
One-week change between post-overreaching and post-taper.

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Palacky University

Efterforskere

  • Ledende efterforsker: Jan Kvas, Palacky University

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Anslået)

1. august 2026

Primær færdiggørelse (Anslået)

1. december 2026

Studieafslutning (Anslået)

1. december 2026

Datoer for studieregistrering

Først indsendt

15. juli 2026

Først indsendt, der opfyldte QC-kriterier

15. juli 2026

Først opslået (Faktiske)

20. juli 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

20. juli 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

15. juli 2026

Sidst verificeret

1. juli 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Andre undersøgelses-id-numre

  • FTK_2026_13

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

JA

IPD-planbeskrivelse

All IPD that underlie results in a publication.

IPD-delingstidsramme

Beginning 1 month after the publication of results with no end date.

IPD-delingsadgangskriterier

Anonymized IPD will be uploaded to an open-access data repository.

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