Impact of Periodontitis Grading on Peri-Implant Clinical and Bone Health: A 60-Month Prospective Study
Impact of Periodontitis Grading on Clinical and Bone Peri-Implant Health: Longitudinal, Prospective, 60-Month Follow-Up Study
This prospective cohort study evaluated the effect of periodontitis grading on peri-implant clinical and radiographic outcomes over a 60-month follow-up. Fifty-five partially edentulous patients were classified into three groups according to periodontal status: generalized aggressive periodontitis (Grade C), generalized chronic periodontitis (Grade B), and no history of periodontitis. A total of 92 implants (tissue- or bone-level) were placed and restored with single crowns, followed by biannual supportive periodontal therapy.
Peri-implant clinical parameters (probing depth, clinical attachment level, plaque index, and bleeding on probing), marginal bone level changes, peri-implantitis incidence, and implant survival were assessed up to 60 months after prosthetic loading.
The objective was to determine whether periodontal history and grading influence long-term peri-implant outcomes under maintenance therapy.
Tutkimuksen yleiskatsaus
Tila
Yksityiskohtainen kuvaus
This prospective cohort study was conducted to evaluate the long-term influence of a history of periodontitis on peri-implant clinical and radiographic outcomes in partially edentulous patients. Patients were classified according to their periodontal status into three groups: generalized aggressive periodontitis (currently classified as Grade C periodontitis), generalized chronic periodontitis (Grade B periodontitis), and individuals without a history of periodontitis.
A total of 55 patients received 92 dental implants, either tissue-level or bone-level, placed in healed sites and restored with single screw-retained crowns. All patients were enrolled in a structured supportive periodontal therapy program and were followed for 60 months after prosthetic loading.
Peri-implant and periodontal health were assessed longitudinally using clinical parameters (probing depth, clinical attachment levels, plaque accumulation, and bleeding on probing) as well as radiographic evaluation of marginal bone level changes. Assessments were performed at multiple time points throughout follow-up to monitor tissue stability and disease occurrence.
The primary aim of the study was to compare peri-implant outcomes among patients with different periodontal backgrounds and to determine whether a history and severity of periodontitis influence long-term implant success and disease incidence under strict maintenance conditions. Secondary outcomes included evaluation of marginal bone remodeling, incidence of peri-implantitis, and implant survival over time.
Opintotyyppi
Ilmoittautuminen (Todellinen)
Osallistumiskriteerit
Kelpoisuusvaatimukset
Opintokelpoiset iät
- Aikuinen
- Vanhempi Aikuinen
Hyväksyy terveitä vapaaehtoisia
Näytteenottomenetelmä
Tutkimusväestö
Kuvaus
Inclusion Criteria:
- Age ≥ 18 years.
- Previous diagnosis of aggressive periodontitis, chronic periodontitis, or no history of periodontitis.
- Completion of periodontal treatment at least 1 year before study enrollment.
- Enrollment in supportive periodontal therapy.
- Plaque Index < 20% at study onset.
- Bleeding on Probing < 20% at study onset.
- Presence of at least one single edentulous space with adjacent teeth.
- Sufficient bone and soft tissue volume for implant placement without the need for reconstructive procedures.
Exclusion Criteria:
- Systemic conditions that contraindicate implant surgery.
- Use of systemic antimicrobial therapy within 6 months before implant placement.
- Untreated or uncontrolled aggressive periodontitis.
- Untreated or uncontrolled chronic periodontitis.
- Pregnancy or breastfeeding.
- Need for bone grafting or soft tissue grafting procedures.
- Current smokers or former smokers.
Opintosuunnitelma
Miten tutkimus on suunniteltu?
Suunnittelun yksityiskohdat
Kohortit ja interventiot
Ryhmä/Kohortti |
|---|
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GAP Group
Patients with a history of generalized aggressive periodontitis, rehabilitated with dental implants.
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GCP Group
Patients with a history of generalized chronic periodontitis, rehabilitated with dental implants.
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PPH Group
Periodontally healthy patients or Patients with no history of periodontitis (no site with probing depth > 3mm and bleeding on probing < 20%)
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Mitä tutkimuksessa mitataan?
Ensisijaiset tulostoimenpiteet
Tulosmittaus |
Toimenpiteen kuvaus |
Aikaikkuna |
|---|---|---|
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Marginal bone level changes around dental implants evaluated radiographically.
Aikaikkuna: Over a 60-month follow-up period.
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Primary Outcome
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Over a 60-month follow-up period.
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Toissijaiset tulostoimenpiteet
Tulosmittaus |
Toimenpiteen kuvaus |
Aikaikkuna |
|---|---|---|
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Peri-implant probing depth (PPD) at follow-up visits
Aikaikkuna: Over a 60-month follow-up period
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Secondary Outcome Measure
|
Over a 60-month follow-up period
|
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Bleeding on probing (BoP) around implants
Aikaikkuna: 60 months follow-up
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60 months follow-up
|
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Implant survival rate
Aikaikkuna: 60 months follow-up
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60 months follow-up
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Yhteistyökumppanit ja tutkijat
Sponsori
Julkaisuja ja hyödyllisiä linkkejä
Yleiset julkaisut
- Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, Chen S, Cochran D, Derks J, Figuero E, Hammerle CHF, Heitz-Mayfield LJA, Huynh-Ba G, Iacono V, Koo KT, Lambert F, McCauley L, Quirynen M, Renvert S, Salvi GE, Schwarz F, Tarnow D, Tomasi C, Wang HL, Zitzmann N. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018 Jun;89 Suppl 1:S313-S318. doi: 10.1002/JPER.17-0739.
- Karoussis IK, Salvi GE, Heitz-Mayfield LJ, Bragger U, Hammerle CH, Lang NP. Long-term implant prognosis in patients with and without a history of chronic periodontitis: a 10-year prospective cohort study of the ITI Dental Implant System. Clin Oral Implants Res. 2003 Jun;14(3):329-39. doi: 10.1034/j.1600-0501.000.00934.x.
- Pimentel SP, Shiota R, Cirano FR, Casarin RCV, Pecorari VGA, Casati MZ, Haas AN, Ribeiro FV. Occurrence of peri-implant diseases and risk indicators at the patient and implant levels: A multilevel cross-sectional study. J Periodontol. 2018 Sep;89(9):1091-1100. doi: 10.1002/JPER.17-0599. Epub 2018 Aug 8.
- Salvi GE, Stahli A, Imber JC, Sculean A, Roccuzzo A. Physiopathology of peri-implant diseases. Clin Implant Dent Relat Res. 2023 Aug;25(4):629-639. doi: 10.1111/cid.13167. Epub 2022 Dec 14.
- Lang NP. Implant Dentistry: The Past, the Present, the Future. J Periodontal Res. 2025 Feb;60(2):97-100. doi: 10.1111/jre.13388. Epub 2025 Feb 21. No abstract available.
Opintojen ennätyspäivät
Opi tärkeimmät päivämäärät
Opiskelun aloitus (Todellinen)
Ensisijainen valmistuminen (Todellinen)
Opintojen valmistuminen (Todellinen)
Opintoihin ilmoittautumispäivät
Ensimmäinen lähetetty
Ensimmäinen toimitettu, joka täytti QC-kriteerit
Ensimmäinen Lähetetty (Todellinen)
Tutkimustietojen päivitykset
Viimeisin päivitys julkaistu (Todellinen)
Viimeisin lähetetty päivitys, joka täytti QC-kriteerit
Viimeksi vahvistettu
Lisää tietoa
Tähän tutkimukseen liittyvät termit
Muita asiaankuuluvia MeSH-ehtoja
Muut tutkimustunnusnumerot
- 0015.0.167.0000-10
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