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Muscular Fatigue vs. Mental Fatigue on Balance, Proprioception and Reaction Time

8 juillet 2026 mis à jour par: Çiçek Günday, Istinye University

Comparison of the Effects of Extremity Fatigue and Mental Fatigue on Balance, Proprioception and Reaction Time

This study aims to understand how different types of fatigue affect balance and reaction time, proprioception, and fine motor in healthy young adults. Fatigue is a common experience in daily life and can arise from physical activity or prolonged mental effort. The study seeks to determine whether fatigue of the upper body, lower body, or mental fatigue from cognitively demanding tasks can negatively affect balance and reaction time, proprioception, and fine motor abilities.

To examine this, participants will undergo controlled fatigue protocols designed to tire specific parts of the body or the mind. the Upper body fatigue will be induced through repeated maximal push-up sets performed until the participant can no longer maintain proper form. Lower body fatigue will be created through repeated maximal 1-minute squat jump sets, with participants touching a low box to ensure standardized depth and proper movement. Mental fatigue will be induced using a 20-minute computer-based cognitive task that alternates between the 2-back working memory task and the numerical Stroop task. These tasks are designed to require continuous attention, mental effort, and inhibitory control. Each type of fatigue will be induced independently, and participants' performance will be measured before and after each fatigue protocol.

Following fatigue induction, participants will complete a series of tests designed to assess balance and reaction time, proprioception, and fine motor abilities. This includes both static and dynamic postural tasks, as well as reaction time and proprioceptive accuracy assessments. By evaluating these measures before and after fatigue, the study will determine how different forms of physical and mental fatigue impact postural stability, sensory processing, and precise motor control.

The study addresses the question: "Do upper body fatigue, lower body fatigue, or mental fatigue reduce balance and reaction time, proprioception, and fine motor performance in healthy young adults?" The hypothesis is that each form of fatigue upper body, lower body, or mental-will meaningfully impair balance and reaction time, proprioception, and fine motor performance compared to non-fatigued conditions.

Aperçu de l'étude

Type d'étude

Interventionnel

Inscription (Réel)

71

Phase

  • N'est pas applicable

Contacts et emplacements

Cette section fournit les coordonnées de ceux qui mènent l'étude et des informations sur le lieu où cette étude est menée.

Lieux d'étude

      • Istanbul, Turquie (Türkiye)
        • Istinye University Research and Application Center (ISUFIZYOTEM)

Critères de participation

Les chercheurs recherchent des personnes qui correspondent à une certaine description, appelée critères d'éligibilité. Certains exemples de ces critères sont l'état de santé général d'une personne ou des traitements antérieurs.

Critère d'éligibilité

Âges éligibles pour étudier

  • Adulte

Accepte les volontaires sains

Oui

La description

Inclusion Criteria:

  • Being between 18 and 35 years of age
  • Self-reporting good general health status
  • Not having any physician-diagnosed medical condition
  • Not using any assistive device or orthotic insoles

Exclusion Criteria:

  • History of neurological disorders affecting balance (e.g., stroke, Parkinson's disease, multiple sclerosis, vestibular disorders)
  • Current or recent (within the past 6 months) lower extremity or spinal injury
  • Current lower extremity pain
  • Uncontrolled cardiovascular disease
  • Uncorrected visual impairment affecting balance
  • Current pregnancy

Plan d'étude

Cette section fournit des détails sur le plan d'étude, y compris la façon dont l'étude est conçue et ce que l'étude mesure.

Comment l'étude est-elle conçue ?

Détails de conception

  • Objectif principal: Autre
  • Répartition: Randomisé
  • Modèle interventionnel: Affectation parallèle
  • Masquage: Seul

Armes et Interventions

Groupe de participants / Bras
Intervention / Traitement
Expérimental: Upper Extremity Fatigue
The upper extremity fatigue will be created by requiring participants to perform consecutive sets of push-ups until task failure. Push-ups will be executed according to standardized ACSM guidelines, and repetitions will be recorded. Participants will first complete one maximal set to exhaustion, followed by a 1-minute rest period and a second maximal set. If performance in the second set exceeds 60% of the initial repetition count, additional sets will be performed after 1-minute recovery intervals. This sequence will continue until the participant's performance declines below 60% of the previous set, at which point neuromuscular fatigue will be considered achieved.
Expérimental: Lower Extremity Fatigue
The lower extremity fatigue will be created by requiring participants to perform repeated 1-minute sets of maximal squat jumps until exhaustion. During each jump, participants will execute countermovement jumps and touch a low box with their hips to ensure standardized depth, under researcher supervision for proper technique. After completing an initial 1-minute maximal set, total jump count will be recorded. Following a 1-minute recovery period, a second 1-minute maximal set will be performed. If performance in the second set exceeds 60% of the first set's total repetitions, additional 1-minute sets will be completed after 1-minute rest intervals. This procedure will continue until jump performance declines below 60% of the previous set, at which point neuromuscular fatigue will be considered achieved.
Expérimental: Mental Fatigue
Mental Fatigue will be created by administering a continuous 20-minute computerized cognitive protocol composed of four consecutive 5-minute blocks without rest. The 2-back task (5 minutes) and the numerical Stroop task (5 minutes) will each be performed twice in alternating order. The sustained and repeated working memory and inhibitory control demands are intended to induce progressive cognitive load and mental fatigue.

Que mesure l'étude ?

Principaux critères de jugement

Mesure des résultats
Description de la mesure
Délai
Y Balance Test (YBT)
Délai: Day 1

The assessment will be performed using a standard YBT kit, which includes a central stance platform and three measurement tapes extending in the anterior (ANT), posteromedial (PM), and posterolateral (PL) directions.

Participants will stand barefoot on their dominant leg on the central platform. While maintaining balance and keeping the stance foot stationary, they will reach as far as possible in each of the three directions with the contralateral leg to push a reach indicator. To ensure maximum performance, three trials will be conducted for each direction, and the best score (maximum reach distance) will be recorded for analysis.

Day 1
BlazePod Reaction System for Lower Extremity
Délai: Day 1
Four pods will be arranged in a square configuration at a distance equal to the participant's leg length. Participants stand barefoot in the center on one leg for 30 seconds. They must tap the illuminated pods with their raised foot as quickly as possible without the raised foot touching the ground more than once.
Day 1
BlazePod Reaction System for Upper Extremity
Délai: Day 1
Four pods will be arranged in a rectangular layout (91 cm long and 30 cm wide), with two pods on each side. The protocol follows the same principles as the lower extremity test. Performance is measured by the total number of "hits" and the average RT between responses.
Day 1

Mesures de résultats secondaires

Mesure des résultats
Description de la mesure
Délai
Ruler Drop Reaction Test
Délai: Day 1
The Ruler Drop Reaction Test will be performed using a standard 30-centimeter ruler to assess simple visual reaction time. The protocol requires the participant to sit parallel to a table with the elbow flexed at 90° and resting on the surface. The dominant hand will be extended, with the thumb and index finger positioned at the 0 cm mark without touching the ruler. The researcher will hold the ruler vertically, aligning the zero point with the top of the participant's thumb and index finger, and release it without warning. The participant will attempt to catch the ruler as quickly as possible. The distance the ruler falls (in centimeters) will be measured from the 0 cm mark to the top of the participant's thumb. Three trials will be conducted for both the dominant and non-dominant hands, and the best performance (shortest distance) will be used for data analysis.
Day 1
Purdue Pegboard Test (PPT)
Délai: Day 1
The Purdue Pegboard Test (PPT) will be utilized to evaluate fine motor skills and the coordinated movement of the hands, fingers, and arms. Participants will sit comfortably in front of the pegboard to perform four distinct batteries, where the score for each section is determined by the number of items successfully placed or assembled within the allotted time. The first and second sections involve individual pin placement for 30 seconds using the dominant and non-dominant hands respectively; the third section requires simultaneous bimanual pin placement for 30 seconds; and the final section tests the ability to assemble pins, collars, and washers using both hands over a 60-second duration.
Day 1
Joint Position Sense Test (JPS Test)
Délai: Day 1
To ensure measurement precision, fixed anatomical landmarks-the greater trochanter, the lateral knee joint space, and the lateral malleolus-will be marked. At the start of the test, the participant will be positioned with the knee and hip joints at 90°. The researcher will passively move the participant's leg to a target angle of 45° flexion. After holding this position briefly, the leg will be returned to the starting position. Participants will be blindfolded to eliminate visual feedback. They will then be asked to actively reproduce the target angle. The absolute difference between the target angle and the actively reproduced angle will be recorded as the test score.
Day 1

Collaborateurs et enquêteurs

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Dates d'enregistrement des études

Ces dates suivent la progression des dossiers d'étude et des soumissions de résultats sommaires à ClinicalTrials.gov. Les dossiers d'étude et les résultats rapportés sont examinés par la Bibliothèque nationale de médecine (NLM) pour s'assurer qu'ils répondent à des normes de contrôle de qualité spécifiques avant d'être publiés sur le site Web public.

Dates principales de l'étude

Début de l'étude (Réel)

11 novembre 2025

Achèvement primaire (Réel)

8 juillet 2026

Achèvement de l'étude (Réel)

8 juillet 2026

Dates d'inscription aux études

Première soumission

31 mars 2026

Première soumission répondant aux critères de contrôle qualité

1 juin 2026

Première publication (Réel)

2 juin 2026

Mises à jour des dossiers d'étude

Dernière mise à jour publiée (Réel)

9 juillet 2026

Dernière mise à jour soumise répondant aux critères de contrôle qualité

8 juillet 2026

Dernière vérification

1 juillet 2026

Plus d'information

Termes liés à cette étude

Autres numéros d'identification d'étude

  • ISU-25-099

Plan pour les données individuelles des participants (IPD)

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NON

Informations sur les médicaments et les dispositifs, documents d'étude

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Non

Étudie un produit d'appareil réglementé par la FDA américaine

Non

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