- ICH GCP
- Registre américain des essais cliniques
- Essai clinique NCT07845981
Multi-Component Training Versus Motor Learning Techniques in Adults With ADHD (MCT-MLT)
Comparative Effects of Multi-Component Training and Motor Learning Techniques on Attention, Cognitive Performance, and Motor Coordination in Adults With Attention Deficit Hyperactivity Disorder
This randomized clinical trial aims to compare the effects of multi-component training and motor learning techniques on attention, cognitive performance, and motor coordination in adults with Attention Deficit Hyperactivity Disorder (ADHD). ADHD in adults is associated with impairments in executive function, attention regulation, and motor coordination, which significantly impact daily functioning and quality of life. While pharmacological and behavioral therapies are commonly used, non-pharmacological interventions such as structured exercise and motor learning approaches have shown potential benefits.
A total of 44 participants aged 18-30 years with clinically diagnosed ADHD will be recruited and randomly allocated into two groups. Group A will receive multi-component training including aerobic, resistance, balance, and flexibility exercises, while Group B will receive motor learning techniques focusing on task-oriented and cognitive-motor dual-task training. Both interventions will be administered three times per week for eight weeks.
Outcome measures will include standardized tools assessing attention, executive function, and cognitive performance, including ADHD rating scales and cognitive assessments. Data will be analyzed pre- and post-intervention to determine within-group and between-group differences. This study aims to identify effective, non-pharmacological rehabilitation strategies for improving cognitive and motor outcomes in adults with ADHD.
Aperçu de l'étude
Statut
Les conditions
Intervention / Traitement
Description détaillée
Background and Rationale
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity, persisting into adulthood in a significant proportion of individuals. Adults with ADHD commonly experience deficits in executive function, attention, working memory, and motor coordination, leading to reduced occupational performance, impaired social relationships, and decreased quality of life.
Although pharmacological treatments such as stimulant medications are widely used, they may not be suitable for all individuals due to side effects, contraindications, or limited long-term effectiveness. Therefore, there is increasing interest in non-pharmacological interventions such as structured physical exercise and motor learning techniques, which may enhance neuroplasticity and improve cognitive and motor outcomes.
Multi-component training integrates aerobic, resistance, balance, and flexibility exercises and has been associated with improvements in executive function, attention, and emotional regulation. Motor learning techniques focus on task-oriented training, repetition, feedback, and cognitive-motor integration to improve coordination and functional performance. However, limited research has directly compared these two approaches in adults with ADHD.
Objective
To compare the effects of multi-component training and motor learning techniques on attention, cognitive performance, and motor coordination in adults with ADHD.
Study Design
This study will be a single-blind, randomized clinical trial.
Participants
A total of 44 participants aged 18-30 years with clinically diagnosed ADHD will be recruited using non-probability convenience sampling. Participants must meet inclusion criteria including confirmed ADHD diagnosis and ability to participate in moderate physical activity.
Randomization and Blinding
Participants will be randomly assigned to one of two groups using a computer-generated randomization method. Allocation will be concealed using sealed opaque envelopes. The outcome assessor will remain blinded to group allocation.
Interventions
Group A: Multi-Component Training
Participants will undergo a structured exercise program including:
Aerobic training (moderate intensity) Resistance training using light weights or bands Balance and flexibility exercises Sessions will be conducted three times per week for 8 weeks.
Group B: Motor Learning Techniques
Participants will receive:
Task-oriented motor training Cognitive-motor dual-task activities Feedback-based motor learning strategies Sessions will be conducted three times per week for 8 weeks. Outcome Measures
Primary and secondary outcomes will be assessed at baseline and post-intervention using standardized tools:
Adult ADHD Self-Report Scale (ASRS) Montreal Cognitive Assessment (MoCA) Conners' Adult ADHD Rating Scales (CAARS) Stroop Color and Word Test Trail Making Test (Parts A and B) Digit Span Test Behavior Rating Inventory of Executive Function (BRIEF-A) Data Analysis
Data will be analyzed using SPSS version 27. Descriptive statistics will summarize participant characteristics. Normality will be assessed using the Shapiro-Wilk test.
Within-group comparisons: Paired t-test or Wilcoxon signed-rank test Between-group comparisons: Independent t-test or Mann-Whitney U test Statistical significance set at p < 0.05 Expected Outcome
This study is expected to determine whether multi-component training or motor learning techniques are more effective in improving attention, cognitive performance, and motor coordination in adults with ADHD. Findings may contribute to evidence-based, non-pharmacological rehabilitation strategies for ADHD management.
Type d'étude
Inscription (Estimé)
Phase
- N'est pas applicable
Contacts et emplacements
Coordonnées de l'étude
- Nom: Ambreen iqbal
- Numéro de téléphone: +92 322 7616154
- E-mail: iqbalambreen8@gmail.com
Sauvegarde des contacts de l'étude
- Nom: Wajeeha Zia
- Numéro de téléphone: +92 323 450078
- E-mail: wajeeha.zia@riphah.edu.pk
Lieux d'étude
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Punjab Province
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Lahore, Punjab Province, Pakistan, 54000
- Shalamar Hospital and Ali Hospital
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Contact:
- Ambreen iqbal, phd*
- Numéro de téléphone: 03227616154
- E-mail: iqbalambreen8@gmail.com
-
Contact:
- wajeeha zia, phd*
- Numéro de téléphone: +923227616154
- E-mail: iqbalambreen8@gmail.com
-
-
Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
Accepte les volontaires sains
Sexes éligibles pour l'étude
La description
Inclusion Criteria:
- Male and female adults aged 18 to 30 years.
- Clinically diagnosed with Attention Deficit Hyperactivity Disorder.
- Adult ADHD Self-Report Scale score indicating ADHD symptoms.
- Montreal Cognitive Assessment score less than 26 out of 30.
- Medically stable and able to participate in moderate physical activity.
- Not currently participating in any other structured cognitive or physical intervention program.
- Able to attend supervised sessions three times per week for 8 weeks.
- Willing to provide written informed consent.
Exclusion Criteria:
- History of systemic or neurological disorders.
- Currently undergoing treatment for ADHD or participating in similar interventions.
- Physical limitations preventing participation in physical activity.
- Severe psychiatric conditions such as schizophrenia or bipolar disorder.
- Uncontrolled cardiovascular conditions or medical contraindications to moderate physical activity.
- Taking medications that significantly alter cognitive or motor performance unless stabilized for at least 3 months.
- History of substance abuse within the past 12 months.
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
- Objectif principal: Traitement
- Répartition: Randomisé
- Modèle interventionnel: Affectation parallèle
- Masquage: Seul
Armes et Interventions
Groupe de participants / Bras |
Intervention / Traitement |
|---|---|
|
Expérimental: Multi-Component Training Group
Participants in this group will receive multi-component training including warm-up, aerobic training, resistance training, balance and flexibility exercises, breathing exercises, and cool-down. Sessions will be conducted three times per week for 8 weeks, with each session lasting approximately 30-40 minutes. |
Multi-component training will include warm-up, moderate-intensity aerobic exercise, resistance training using light weights or resistance bands, balance and flexibility exercises, breathing exercises, and cool-down. Sessions will be supervised three times per week for 8 weeks, with each session lasting approximately 30-40 minutes.
Autres noms:
|
|
Comparateur actif: Motor Learning Techniques Group
Participants in this group will receive motor learning techniques including warm-up, task-oriented training, cognitive-motor dual-task activities, feedback-based learning, and cool-down. Sessions will be conducted three times per week for 8 weeks, with each session lasting approximately 30-40 minutes. |
Motor learning techniques will include warm-up, task-oriented functional motor activities, cognitive-motor dual-task exercises, feedback-based learning, and cool-down. Sessions will be supervised three times per week for 8 weeks, with each session lasting approximately 30-40 minutes.
Autres noms:
|
Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
Conners' Adult ADHD Rating Scale
Délai: 8 weeks of treatment (Pre & Post)
|
Adult ADHD symptom severity will be assessed using the Conners' Adult ADHD Rating Scales (CAARS). |
8 weeks of treatment (Pre & Post)
|
Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
Purdue Pegboard Test
Délai: Baseline and immediately after completion of the 8-week intervention
|
Dominant-hand motor coordination and manual dexterity will be assessed using the Purdue Pegboard Test. |
Baseline and immediately after completion of the 8-week intervention
|
|
Trial Making Test
Délai: 8 weeks of intervention (Pre & Post)
|
Performance was assessed by noting the overall completion time for each segment in seconds |
8 weeks of intervention (Pre & Post)
|
Collaborateurs et enquêteurs
Parrainer
Les enquêteurs
- Chercheur principal: Wajeeha zia, Riphah International University Role
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude (Estimé)
Achèvement primaire (Estimé)
Achèvement de l'étude (Estimé)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Réel)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Réel)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Mots clés
Termes MeSH pertinents supplémentaires
- Les troubles mentaux
- Troubles neurodéveloppementaux
- Déficit de l'attention et troubles du comportement perturbateur
- Trouble déficitaire de l'attention avec hyperactivité
- Activité motrice
- Mouvement
- Phénomènes physiologiques musculo-squelettiques
- Phénomènes physiologiques musculo-squelettiques et neuronaux
- Exercice
Autres numéros d'identification d'étude
- AIMEN-ABBAS
Plan pour les données individuelles des participants (IPD)
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Informations sur les médicaments et les dispositifs, documents d'étude
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