High-Intensity Interval Training for Stage I-III Breast Cancer Patients

Inclusion Criteria:

• English or Spanish speaking
• Diagnosed with early stage (I-III) breast cancer, without evidence of metastatic disease
• Planned (neo)adjuvant therapy with trastuzumab (Herceptin) and/or anthracycline-based chemotherapy
• Not currently pregnant or planning to become pregnant throughout the duration of cancer treatment
• Physician (oncologist) clearance to participate in exercise at moderate to high intensity
• Have read and signed study informed consent document (ICF)
• EXERCISE INCLUSION CRITERIA:
• Normal body temperature (=< 100 degrees F)
• Resting blood pressure and/or heart rate within normal limits
• Participants have not received intravenous or oral chemotherapy on the same day and prior to scheduled exercise session

Exclusion Criteria:

• Advanced stage (stage IV) or metastatic breast cancer diagnosis (screening for metastases with scans only needed if there is clinical suspicion for metastases)
• Medical history of coronary heart or artery disease, chronic or acute congestive heart failure or history of systolic or diastolic insufficiencies
• Uncontrolled hypertension or other uncontrolled chronic disease (e.g. diabetes mellitus, thyroid disease, pulmonary disease, etc.)
• Moderate to highly active level of physical activity (e.g. currently participating in >= 60 minutes of moderate aerobic activity weekly)
• Orthopedic or other restrictions or contraindications to high-intensity (cycling) exercise
• EXERCISE EXCLUSION CRITERIA:
• Presence of fever (>= 100 degrees F)
• Resting blood pressure and/or heart rate outside normal limits
• Participants have received intravenous or oral chemotherapy on the same day and prior to scheduled exercise session