Effects of Inter-Set Rest Intervals on Muscle Damage After Flywheel Exercise in Untrained Men (RCT)
2026年9月8日 更新者：Federal University of Vicosa
Effects of Different Inter-Set Rest Intervals on Indirect Markers of Muscle Damage and Mechanical Parameters After Flywheel Resistance Training in Untrained Men: A Randomized Parallel-Group Clinical Trial
This randomized parallel-group clinical trial will compare the acute effects of three different inter-set rest intervals during a single lower-limb flywheel resistance exercise session in untrained men.
Participants will be randomly allocated to one of three groups: 1-minute, 2-minute, or 3-minute inter-set rest interval.
The primary outcome will be the change in maximal voluntary isometric contraction of the knee extensors 48 hours after exercise.
Secondary outcomes will include mechanical variables during the exercise session, countermovement jump performance, knee flexor maximal voluntary isometric contraction, muscle soreness, pressure pain threshold, range of motion, ultrasound-derived muscle thickness and echo intensity, perceived exertion, perceived discomfort, perceived recovery status, creatine kinase, and lactate dehydrogenase.
調査の概要
状態
募集
条件
詳細な説明
Participants will complete seven laboratory visits. The first two visits will be used for baseline assessments and test-retest reliability. The third and fourth visits will be used for technical familiarization with the flywheel exercises. The fifth visit will include the experimental flywheel resistance exercise session and immediate post-exercise assessments. The sixth and seventh visits will include follow-up assessments 48 and 96 hours after the experimental session, respectively. Blood samples for creatine kinase and lactate dehydrogenase will be collected before the experimental session and 72 hours after exercise in a partner laboratory.
The experimental session will include squat, Romanian deadlift, knee extension, and knee flexion exercises performed using flywheel devices. All groups will perform the same exercises, volume, inertia, and execution instructions. The only difference between groups will be the inter-set rest interval: 1 minute, 2 minutes, or 3 minutes.
研究の種類
介入
入学 (推定)
30
段階
- 適用できない
連絡先と場所
このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。
研究場所
-
-
Minas Gerais
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Viçosa、Minas Gerais、ブラジル、36570-900
- 募集
- Federal University of Vicosa
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コンタクト：
- Study Coordinator
- 電話番号：(31) 98359-5541
- メール：wanderson.machado@ufv.br
-
-
参加基準
研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。
適格基準
就学可能な年齢
- 大人
健康ボランティアの受け入れ
はい
説明
Inclusion Criteria:
- Age between 18 and 40 years;
- Apparently healthy and clinically able to perform physical exercise;
- No participation in structured resistance training during the previous 6 months;
- Agreement to comply with all study visits and procedures;
- Signed informed consent form.
Exclusion Criteria:
- History of lower-limb musculoskeletal injury or surgery that may impair performance or safety during the proposed exercise protocol;
- Current pain, injury, or functional limitation in the lower limbs;
- Use of ergogenic aids that may affect physical performance or muscle recovery;
- Use of analgesic or anti-inflammatory medication during the study period;
- Failure to attend the scheduled visits required for the primary outcome assessment.
研究計画
このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。
研究はどのように設計されていますか？
デザインの詳細
- 主な目的：基礎科学
- 割り当て：ランダム化
- 介入モデル：並列代入
- マスキング：なし（オープンラベル）
武器と介入
参加者グループ / アーム |
介入・治療 |
|---|---|
|
実験的：1-Minute Inter-set Rest Interval
Participants allocated to this group will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
|
Participants will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
Each exercise will be performed for 4 sets of 2 preparatory repetitions followed by 8 valid repetitions, using the same flywheel inertia, exercise order, and execution instructions across all groups.
Participants will be instructed to perform the concentric phase as fast as possible and to brake the eccentric phase during the final portion of the movement.
The interval between exercises will be standardized at 3 minutes.
|
|
実験的：2-Minute Inter-set Rest Interval
Participants allocated to this group will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
|
Participants will perform a single lower-limb flywheel resistance exercise session using a 2-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
Each exercise will be performed for 4 sets of 2 preparatory repetitions followed by 8 valid repetitions, using the same flywheel inertia, exercise order, and execution instructions across all groups.
Participants will be instructed to perform the concentric phase as fast as possible and to brake the eccentric phase during the final portion of the movement.
The interval between exercises will be standardized at 3 minutes.
|
|
実験的：3-Minute Inter-set Rest Interval
Participants allocated to this group will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
|
Participants will perform a single lower-limb flywheel resistance exercise session using a 3-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
Each exercise will be performed for 4 sets of 2 preparatory repetitions followed by 8 valid repetitions, using the same flywheel inertia, exercise order, and execution instructions across all groups.
Participants will be instructed to perform the concentric phase as fast as possible and to brake the eccentric phase during the final portion of the movement.
The interval between exercises will be standardized at 3 minutes.
|
この研究は何を測定していますか？
主要な結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Change in maximal voluntary isometric contraction of the knee extensors
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Maximal voluntary isometric contraction of the knee extensors will be assessed using a load cell with the knee positioned at 90 degrees of flexion.
The primary outcome will be the change in force between baseline and immediately, 48 hours, and 96 hours after the experimental exercise session using a flywheel.
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
|
Change in maximal voluntary isometric contraction of the knee flexors
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
The maximum voluntary isometric contraction of the knee flexors will be assessed using a load cell with the knee positioned at 45 degrees of flexion.
The primary outcome will be the change in force between baseline and immediately, 48 hours, and 96 hours after the experimental exercise session using a flywheel.
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
二次結果の測定
結果測定 |
メジャーの説明 |
時間枠 |
|---|---|---|
|
Change in vastus lateralis and biceps femoris long head muscle thickness
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
|
|
Change in vastus lateralis and biceps femoris long head echo intensity
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
|
|
Change in countermovement jump performance
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
|
|
Change in active and passive knee flexion and extension range of motion
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
|
|
Change in lower-limb muscle soreness score assessed by the Visual Analogue Scale
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Lower-limb muscle soreness will be assessed using a 100-mm Visual Analogue Scale.
The scale ranges from 0 to 100, where 0 indicates no pain and 100 indicates the worst possible pain.
Higher scores indicate greater muscle soreness.
The outcome will be reported as the change in muscle soreness score from baseline to the post-exercise time points.
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
|
Change in pressure pain threshold of the thigh muscles
時間枠：Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
|
|
Change in serum creatine kinase and lactate dehydrogenase concentrations
時間枠：Pre-exercise and 72 hours after the experimental exercise session
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Pre-exercise and 72 hours after the experimental exercise session
|
|
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Peak concentric and eccentric power output during flywheel exercise
時間枠：During all 16 sets performed in the experimental exercise session
|
Peak concentric and eccentric power output will be recorded during each valid repetition of the flywheel exercise session using a load cell connected to the flywheel device.
Data will be collected for all sets and exercises, excluding the initial preparatory repetitions.
The outcome will be reported as peak concentric power, peak eccentric power, and eccentric/concentric power ratio across the experimental exercise session.
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During all 16 sets performed in the experimental exercise session
|
|
Rating of perceived exertion assessed by the OMNI-Resistance Exercise Scale
時間枠：After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
|
Rating of perceived exertion will be assessed using the OMNI-Resistance Exercise Scale.
The scale ranges from 0 to 10, where 0 indicates extremely easy and 10 indicates extremely hard.
Higher scores indicate greater perceived exertion.
The outcome will be reported after each set of the experimental flywheel exercise session and 10 minutes after the end of the session.
|
After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
|
|
Perceived discomfort assessed by the Discomfort Scale
時間枠：After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
|
Perceived discomfort will be assessed using a 0-to-100 Discomfort Scale.
The scale ranges from 0 to 100, where 0 indicates no discomfort and 100 indicates maximal discomfort.
Higher scores indicate greater perceived discomfort.
The outcome will be reported after each set of the experimental flywheel exercise session and 10 minutes after the end of the session.
|
After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
|
|
Perceived recovery status assessed by the Perceived Recovery Status Scale
時間枠：Baseline, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
Perceived recovery status will be assessed using the Perceived Recovery Status Scale.
The scale ranges from 0 to 10, where 0 indicates very poor recovery and 10 indicates full recovery.
Higher scores indicate better perceived recovery.
The outcome will be reported as the perceived recovery status score at baseline and at the post-exercise follow-up time points.
|
Baseline, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
|
協力者と研究者
ここでは、この調査に関係する人々や組織を見つけることができます。
研究記録日
これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。
主要日程の研究
研究開始 (実際)
2026年6月1日
一次修了 (推定)
2026年10月1日
研究の完了 (推定)
2026年10月1日
試験登録日
最初に提出
2026年5月29日
QC基準を満たした最初の提出物
2026年6月25日
最初の投稿 (実際)
2026年7月1日
学習記録の更新
投稿された最後の更新 (実際)
2026年9月11日
QC基準を満たした最後の更新が送信されました
2026年9月8日
最終確認日
2026年9月1日
詳しくは
本研究に関する用語
その他の研究ID番号
- 7.151.525 (その他の識別子：Ethics Committee Approval Number)
- 81740024.5.0000.5153 (その他の識別子：CAAE)
個々の参加者データ (IPD) の計画
個々の参加者データ (IPD) を共有する予定はありますか?
いいえ
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いいえ
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