Effects of Inter-Set Rest Intervals on Muscle Damage After Flywheel Exercise in Untrained Men (RCT)
2026년 6월 25일 업데이트: Federal University of Vicosa
Effects of Different Inter-Set Rest Intervals on Indirect Markers of Muscle Damage and Mechanical Parameters After Flywheel Resistance Training in Untrained Men: A Randomized Parallel-Group Clinical Trial
This randomized parallel-group clinical trial will compare the acute effects of three different inter-set rest intervals during a single lower-limb flywheel resistance exercise session in untrained men.
Participants will be randomly allocated to one of three groups: 1-minute, 2-minute, or 3-minute inter-set rest interval.
The primary outcome will be the change in maximal voluntary isometric contraction of the knee extensors 48 hours after exercise.
Secondary outcomes will include mechanical variables during the exercise session, countermovement jump performance, knee flexor maximal voluntary isometric contraction, muscle soreness, pressure pain threshold, range of motion, ultrasound-derived muscle thickness and echo intensity, perceived exertion, perceived discomfort, perceived recovery status, creatine kinase, and lactate dehydrogenase.
연구 개요
상태
아직 모집하지 않음
상세 설명
Participants will complete seven laboratory visits. The first two visits will be used for baseline assessments and test-retest reliability. The third and fourth visits will be used for technical familiarization with the flywheel exercises. The fifth visit will include the experimental flywheel resistance exercise session and immediate post-exercise assessments. The sixth and seventh visits will include follow-up assessments 48 and 96 hours after the experimental session, respectively. Blood samples for creatine kinase and lactate dehydrogenase will be collected before the experimental session and 72 hours after exercise in a partner laboratory.
The experimental session will include squat, Romanian deadlift, knee extension, and knee flexion exercises performed using flywheel devices. All groups will perform the same exercises, volume, inertia, and execution instructions. The only difference between groups will be the inter-set rest interval: 1 minute, 2 minutes, or 3 minutes.
연구 유형
중재적
등록 (추정된)
30
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 장소
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Minas Gerais
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Viçosa, Minas Gerais, 브라질, 36570-900
- Federal University of Vicosa
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연락하다:
- Study Coordinator
- 전화번호: (31) 98359-5541
- 이메일: wanderson.machado@ufv.br
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참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
예
설명
Inclusion Criteria:
- Age between 18 and 40 years;
- Apparently healthy and clinically able to perform physical exercise;
- No participation in structured resistance training during the previous 6 months;
- Agreement to comply with all study visits and procedures;
- Signed informed consent form.
Exclusion Criteria:
- History of lower-limb musculoskeletal injury or surgery that may impair performance or safety during the proposed exercise protocol;
- Current pain, injury, or functional limitation in the lower limbs;
- Use of ergogenic aids that may affect physical performance or muscle recovery;
- Use of analgesic or anti-inflammatory medication during the study period;
- Failure to attend the scheduled visits required for the primary outcome assessment.
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 기초 과학
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
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실험적: 1-Minute Inter-set Rest Interval
Participants allocated to this group will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
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Participants will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
Each exercise will be performed for 4 sets of 2 preparatory repetitions followed by 8 valid repetitions, using the same flywheel inertia, exercise order, and execution instructions across all groups.
Participants will be instructed to perform the concentric phase as fast as possible and to brake the eccentric phase during the final portion of the movement.
The interval between exercises will be standardized at 3 minutes.
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실험적: 2-Minute Inter-set Rest Interval
Participants allocated to this group will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
|
Participants will perform a single lower-limb flywheel resistance exercise session using a 2-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
Each exercise will be performed for 4 sets of 2 preparatory repetitions followed by 8 valid repetitions, using the same flywheel inertia, exercise order, and execution instructions across all groups.
Participants will be instructed to perform the concentric phase as fast as possible and to brake the eccentric phase during the final portion of the movement.
The interval between exercises will be standardized at 3 minutes.
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실험적: 3-Minute Inter-set Rest Interval
Participants allocated to this group will perform a single lower-limb flywheel resistance exercise session using a 1-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
|
Participants will perform a single lower-limb flywheel resistance exercise session using a 3-minute inter-set rest interval.
The session will include squat, Romanian deadlift, knee extension, and knee flexion exercises.
Each exercise will be performed for 4 sets of 2 preparatory repetitions followed by 8 valid repetitions, using the same flywheel inertia, exercise order, and execution instructions across all groups.
Participants will be instructed to perform the concentric phase as fast as possible and to brake the eccentric phase during the final portion of the movement.
The interval between exercises will be standardized at 3 minutes.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Change in maximal voluntary isometric contraction of the knee extensors
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Maximal voluntary isometric contraction of the knee extensors will be assessed using a load cell with the knee positioned at 90 degrees of flexion.
The primary outcome will be the change in force between baseline and immediately, 48 hours, and 96 hours after the experimental exercise session using a flywheel.
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Change in maximal voluntary isometric contraction of the knee flexors
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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The maximum voluntary isometric contraction of the knee flexors will be assessed using a load cell with the knee positioned at 45 degrees of flexion.
The primary outcome will be the change in force between baseline and immediately, 48 hours, and 96 hours after the experimental exercise session using a flywheel.
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Change in vastus lateralis and biceps femoris long head muscle thickness
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Change in vastus lateralis and biceps femoris long head echo intensity
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Change in countermovement jump performance
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Change in active and passive knee flexion and extension range of motion
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Change in lower-limb muscle soreness score assessed by the Visual Analogue Scale
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Lower-limb muscle soreness will be assessed using a 100-mm Visual Analogue Scale.
The scale ranges from 0 to 100, where 0 indicates no pain and 100 indicates the worst possible pain.
Higher scores indicate greater muscle soreness.
The outcome will be reported as the change in muscle soreness score from baseline to the post-exercise time points.
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Change in pressure pain threshold of the thigh muscles
기간: Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Baseline, 10 minutes after the experimental exercise session, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Change in serum creatine kinase and lactate dehydrogenase concentrations
기간: Pre-exercise and 72 hours after the experimental exercise session
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Pre-exercise and 72 hours after the experimental exercise session
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Peak concentric and eccentric power output during flywheel exercise
기간: During all 16 sets performed in the experimental exercise session
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Peak concentric and eccentric power output will be recorded during each valid repetition of the flywheel exercise session using a load cell connected to the flywheel device.
Data will be collected for all sets and exercises, excluding the initial preparatory repetitions.
The outcome will be reported as peak concentric power, peak eccentric power, and eccentric/concentric power ratio across the experimental exercise session.
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During all 16 sets performed in the experimental exercise session
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Rating of perceived exertion assessed by the OMNI-Resistance Exercise Scale
기간: After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
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Rating of perceived exertion will be assessed using the OMNI-Resistance Exercise Scale.
The scale ranges from 0 to 10, where 0 indicates extremely easy and 10 indicates extremely hard.
Higher scores indicate greater perceived exertion.
The outcome will be reported after each set of the experimental flywheel exercise session and 10 minutes after the end of the session.
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After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
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Perceived discomfort assessed by the Discomfort Scale
기간: After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
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Perceived discomfort will be assessed using a 0-to-100 Discomfort Scale.
The scale ranges from 0 to 100, where 0 indicates no discomfort and 100 indicates maximal discomfort.
Higher scores indicate greater perceived discomfort.
The outcome will be reported after each set of the experimental flywheel exercise session and 10 minutes after the end of the session.
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After each of the 16 sets performed during the experimental exercise session and 10 minutes after the experimental exercise session
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Perceived recovery status assessed by the Perceived Recovery Status Scale
기간: Baseline, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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Perceived recovery status will be assessed using the Perceived Recovery Status Scale.
The scale ranges from 0 to 10, where 0 indicates very poor recovery and 10 indicates full recovery.
Higher scores indicate better perceived recovery.
The outcome will be reported as the perceived recovery status score at baseline and at the post-exercise follow-up time points.
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Baseline, 48 hours after the experimental exercise session, and 96 hours after the experimental exercise session
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여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작 (추정된)
2026년 6월 1일
기본 완료 (추정된)
2026년 7월 1일
연구 완료 (추정된)
2026년 7월 1일
연구 등록 날짜
최초 제출
2026년 5월 29일
QC 기준을 충족하는 최초 제출
2026년 6월 25일
처음 게시됨 (실제)
2026년 7월 1일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2026년 7월 1일
QC 기준을 충족하는 마지막 업데이트 제출
2026년 6월 25일
마지막으로 확인됨
2026년 5월 1일
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- 7.151.525 (기타 식별자: Ethics Committee Approval Number)
- 81740024.5.0000.5153 (기타 식별자: CAAE)
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아니요
약물 및 장치 정보, 연구 문서
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아니
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아니
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