Pharmacodynamics Aspects Of Porcine Heparin Sodium, Produced by Eurofarma, Compared Heparin Sodium, Produced by APP Pharmaceuticasls, in Patients With Chronic Renal Failure

Inclusion Criteria:

• Adults of both sexes, regardless of color or social class;
• Age over 18 years, with good clinical doctor's discretion;
• Patients research that agree to participate in the study and sign the informed consent form (attached);
• Chronic renal failure patients in hemodialysis (3 times per week). chronic renal failure patients with indication for anticoagulation during dialysis

Exclusion Criteria:

• Non compliance with the terms described in the informed consent FICT;
• Patients suffering from sensitivity studies heparin sodium;
• Patients with hypersensitivity to search benzyl alcohol;
• Patients with search history of bleeding disorders or disease that a bleeding disorder can worsen or terminate the clinical picture, for example, frames of gastric ulcer;
• Patients with a history of research peptic ulcer;
• Patient with cancer research because of the possibility of impairment of variable coagulation function;
• Patients who are research during pregnancy and postpartum;
• Individuals with a genetic abnormality of the coagulation system;
• Trauma patients;
• Patients on glucocorticoid therapy for at least 1 month;
• Patients using other anticoagulants;
• Patients with a high rate of bleeding;
• Patients undergoing any surgery performed less than 15 days due to the risk of bruising at the site of surgery.
• Patients using drugs that affect hemostasis
• Patients using the following drugs: Salicylates systemic aspirin and other NSAIDs, including ketorolac, Dextran 40, ticlopidine and clopidogrel, systemic glucocorticoids, thrombolytic agents and anticoagulants and other antiplatelet agents, including antagonists of glycoprotein IIb / IIIa.