Effect of Aerobic and Resistance Exercise on Quarry Workers (AE RE VF)
Aerobic Versus Resistance Exercise Training on Ventilatory Function in Quarry Workers
The goal of this randomized clinical trial is to compare the effects of aerobic exercise training and resistance exercise training on ventilatory function in quarry workers. It will also evaluate their effects on functional capacity and health-related quality of life (HRQOL).
The main questions it aims to answer are:
Does aerobic exercise training improve ventilatory function more effectively than resistance exercise training? How do aerobic and resistance exercise training affect functional capacity and health-related quality of life in quarry workers?
Researchers will compare aerobic exercise training and resistance exercise training with a control group receiving routine treatment and breathing exercises to determine which intervention is more effective in improving ventilatory function, functional capacity, and health-related quality of life.
Participants will:
Be randomly assigned to one of three groups: an aerobic exercise training group, a resistance exercise training group, or a control group.
Receive the assigned intervention three times per week for eight consecutive weeks.
Undergo ventilatory function assessment using spirometry. Complete assessments of functional capacity and health-related quality of life before and after the intervention.
연구 개요
상태
상세 설명
Quarry workers are routinely exposed to respirable dust, which increases the risk of impaired ventilatory function and reduced physical performance. Long-term occupational dust exposure has been associated with respiratory symptoms, decreased pulmonary function, and poorer health-related quality of life. Exercise-based pulmonary rehabilitation is widely recommended to improve respiratory function and physical capacity; however, limited evidence is available regarding the comparative effectiveness of aerobic versus resistance exercise training in quarry workers. This randomized clinical trial aims to compare the effects of aerobic exercise training and resistance exercise training on ventilatory function in quarry workers. Secondary outcomes include functional capacity and health-related quality of life (HRQOL). Seventy-five clinically stable male quarry workers aged 30-40 years will be randomly allocated into three equal groups: an aerobic exercise training group, a resistance exercise training group, and a control group.
Participants in the aerobic and resistance exercise groups will receive their assigned exercise program in addition to routine medical treatment and breathing exercise training. The control group will receive routine medical treatment and breathing exercise training only. All interventions will be performed three times per week for eight consecutive weeks.
Ventilatory function will be assessed using spirometry, including Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV1), FEV1/FVC ratio, Peak Expiratory Flow (PEF), and Maximum Voluntary Ventilation (MVV). Functional capacity will be evaluated using the Harvard Step Test, while health-related quality of life will be assessed using the St. George's Respiratory Questionnaire (SGRQ). Outcome measures will be collected at baseline and after completion of the intervention period.
The findings of this study are expected to identify the most effective exercise modality for improving ventilatory function, functional capacity, and health-related quality of life among quarry workers, thereby providing evidence to optimize pulmonary rehabilitation programs for this occupational population.
연구 유형
등록 (추정된)
단계
- 해당 없음
연락처 및 위치
연구 연락처
- 이름: Taher M Kamal Eldin, B.Sc. in physical therapy
- 전화번호: +201004047580
- 이메일: taherkamal364@gmail.com
연구 장소
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Minya Governorate
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Minya, Minya Governorate, 이집트
- 모병
- faculty of physical therapy, Deraya University
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연락하다:
- Taher M Kamal Eldin, BSc in Physical Therapy
- 전화번호: +201004047580
- 이메일: taherkamal364@gmail.com
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참여기준
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
설명
Inclusion Criteria:
- Male quarry workers.
- The age range is between 30 and 40 years.
- BMI values from 25 to 29.9 kg/m².
- They work 5 to 6 times per weeks with mean exposure range (5-10 years) (Kumar et al., 2014). Exhibited chest manifestations (Respiratory symptoms) like cough, dyspnea, wheeze, and ventilatory impairment with significant reduction in (FEV1/FVC<70% and/or FVC<80% and reduce Peak Expiratory flow 25- 75% (PEF25-75%)(Abdelwahaab et al., 2025).
- Clinically stable (no exacerbation in past 4-6 weeks).
- Low levels of physical activity (using the International Physical Activity Questionnaire-Short Version) (The Arabic version of the questionnaire will be used).
Exclusion criteria:
- Patients with acute respiratory infections or recent exacerbation(4-6 weeks).
- Asthmatic patient.
- Chest cancer.
- Musculoskeletal diseases and other disorders that could potentially impact the study's findings are excluded from the trial.
- Other major lung diseases (e.g., TB, ILD, bronchiectasis, cancer).
- Unstable cardiovascular disease.
- Uncontrolled hypertension.
- Severe musculoskeletal or neurological limitation to exercise.
- Cognitive impairment.
- Participation in PR in past 6 months.
- Heavy smokers.
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
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실험적: aerobic exercise group
participants will receive aerobic exercise training in addition to routine medical treatment and breathing exercise training
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participants will receive aerobic exercise training in addition to routine medical treatment and breathing exercise training.
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실험적: resistance exercise group
participants will receive resistance exercise training in addition to routine medical treatment and breathing exercise training.
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participants will receive resistance exercise training in addition to routine medical treatment and breathing exercise training.
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간섭 없음: control group
participants will receive only routine medical treatment and breathing exercise training
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Forced Expiratory Volume in One Second (FEV1)
기간: Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Forced Expiratory Volume in One Second (FEV1) will be assessed using spirometry.
FEV1 is the volume of air forcefully exhaled during the first second of a forced expiratory maneuver and is expressed in liters (L).
Higher values indicate better airway function and ventilatory performance.
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Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Forced Vital Capacity (FVC)
기간: Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Forced Vital Capacity (FVC) will be assessed using spirometry.
FVC is the maximum volume of air that can be forcefully exhaled after a full inspiration and is expressed in liters (L).
Higher values indicate better ventilatory function.
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Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Forced Expiratory Volume in One Second to Forced Vital Capacity Ratio (FEV1/FVC)
기간: Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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The FEV1/FVC ratio will be assessed using spirometry and expressed as a percentage (%).
This parameter reflects the proportion of the forced vital capacity exhaled during the first second of expiration and is commonly used to evaluate airflow limitation.
Higher values generally indicate better ventilatory function.
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Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Forced Expiratory Flow at 25-75% of Forced Vital Capacity (FEF25-75%)
기간: Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention)
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Forced Expiratory Flow at 25-75% of Forced Vital Capacity (FEF25-75%) will be assessed using spirometry.
FEF25-75% represents the average expiratory flow during the middle half of the forced vital capacity maneuver and is expressed in liters per second (L/s).
It is considered a sensitive indicator of small airway function.
Higher values indicate better small airway function and ventilatory performance.
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Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention)
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Maximum Voluntary Ventilation (MVV)
기간: Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Maximum Voluntary Ventilation (MVV) will be assessed using spirometry.
MVV is the maximum volume of air inhaled and exhaled voluntarily within one minute and is expressed in liters per minute (L/min).
Higher values indicate better respiratory muscle endurance and ventilatory capacity.
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Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Health-Related Quality of Life
기간: Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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Health-related quality of life will be assessed using the St. George's Respiratory Questionnaire (SGRQ).
The SGRQ consists of 50 items grouped into three domains: Symptoms, Activity, and Impacts.
Total scores range from 0 to 100, with higher scores indicating poorer health-related quality of life.
Lower scores represent better outcomes
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Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Functional Capacity
기간: Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention)
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Functional capacity will be assessed using the Harvard Step Test.
The Brouha Index (BI) will be calculated based on exercise duration and recovery heart rate.
Higher scores indicate better functional capacity
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Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention)
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공동 작업자 및 조사자
스폰서
수사관
- 연구 의자: Elsayed E Felaya, Assoiate Professor, Cairo University
- 연구 책임자: Shimaa T Taha, Lecturer, Cairo University
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (추정된)
연구 완료 (추정된)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
추가 관련 MeSH 약관
기타 연구 ID 번호
- CU-TMK-19052026
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
IPD 계획 설명
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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