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Anastrozol eller Tamoxifen i behandling av postmenopausale kvinner med duktalt karsinom in situ som gjennomgår lumpektomi og strålebehandling

19. september 2018 oppdatert av: NSABP Foundation Inc

En klinisk studie som sammenligner anastrozol med tamoksifen hos postmenopausale pasienter med ductal carcinoma in situ (DCIS) som gjennomgår lumpektomi med strålebehandling

RASIONAL: Østrogen kan stimulere veksten av brystkreftceller. Tamoxifen kan bekjempe brystkreft ved å blokkere bruken av østrogen. Anastrozol kan bekjempe brystkreft ved å redusere østrogenproduksjonen. Det er ennå ikke kjent om anastrozol er mer effektivt enn tamoxifen for å forhindre tilbakefall av brystkreft.

FORMÅL: Denne randomiserte fase III-studien studerer anastrozol for å se hvor godt det virker sammenlignet med tamoxifen for å forhindre tilbakefall av brystkreft hos postmenopausale kvinner med duktalt karsinom in situ som gjennomgår lumpektomi og strålebehandling.

Studieoversikt

Status

Fullført

Forhold

Brystkreft

Intervensjon / Behandling

Detaljert beskrivelse

MÅL:

Sammenlign verdien av anastrozol vs tamoxifen, når det gjelder forebygging av tilbakefall (dvs. lokale, regionale og fjerne tilbakefall og kontralateral brystkreft), etter lumpektomi og strålebehandling hos postmenopausale kvinner med duktalt karsinom in situ (DCIS).
Sammenlign påfølgende sykdomsforekomst, i form av invasiv brystkreft (lokal, regional, fjern eller kontralateral), ipsilateral og kontralateral brystkreft (invasiv og DCIS), og andre primære maligniteter som ikke er brystkreft, hos pasienter behandlet med disse legemidlene.
Sammenlign livskvalitet og symptomer hos pasienter behandlet med disse legemidlene.*
Sammenlign kvalitetsjustert overlevelsestid for pasienter behandlet med disse legemidlene.*
Sammenlign forekomsten av osteoporotiske frakturer hos pasienter behandlet med disse legemidlene.
Sammenlign sykdomsfri og total overlevelse av pasienter behandlet med disse legemidlene. MERK: *Livskvalitetsstudien stengte for opptjening per 28.12.04.

OVERSIKT: Dette er en randomisert, dobbeltblind, placebokontrollert, multisenterstudie. Pasientene er stratifisert etter alder (under 60 vs 60 og over). Pasientene er randomisert til 1 av 2 behandlingsarmer (arm I og arm II lukket for opptjening per 15.06.06).

Arm I (stengt for opptjening per 15.06.06): Pasienter får oral tamoxifen og oral placebo én gang daglig i 5 år.
Arm II (stengt for opptjening fra 15.06.06): Pasienter får oralt anastrozol og oralt placebo én gang daglig i 5 år.

Fra og med 8 uker etter randomisering gjennomgår alle pasienter også hele bryststrålebehandling, med mindre pasienten er registrert i protokollen NSABP-B-39 og randomisert til den partielle brystbestrålingsgruppen.

Pasientene følges hver 6. måned i 5 år, og deretter årlig.

For pasienter som er registrert i livskvalitetsstudien, vurderes livskvalitet ved baseline og deretter hver 6. måned i 6 år.*

MERK: *Livskvalitetsstudien stengte for opptjening per 28.12.04.

PROSJERT PÅLEGGING: Totalt 3 000 pasienter (1 500 per behandlingsarm) vil bli påløpt for denne studien innen 5 år (arm I og arm II stengt for akkumulering per 15.06.06).

Studietype

Intervensjonell

Registrering (Faktiske)

3104

Fase

Fase 3

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Canada
- Alberta
  - Edmonton, Alberta, Canada, T6G 1Z2
    - Cross Cancer Institute at University of Alberta
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3H 1V8
    - Nova Scotia Cancer Centre
- Ontario
  - Ottawa, Ontario, Canada, K1Y 4K7
    - Ottawa Hospital Regional Cancer Centre - General Campus
  - Toronto, Ontario, Canada, M5G 2M9
    - Princess Margaret Hospital
  - Toronto, Ontario, Canada, M4N 3M5
    - Toronto Sunnybrook Regional Cancer Centre at Sunnybrook Health Sciences Centre
  - Toronto, Ontario, Canada, M5S 1B2
    - Women's College Ambulatory Care Center at Sunnybrook and Women's College Health Science Center
- Quebec
  - Montreal, Quebec, Canada, H2W 1T8
    - Hotel Dieu de Montreal
  - Montreal, Quebec, Canada, H3G 1A4
    - Montreal General Hospital
  - Montreal, Quebec, Canada, H3A 1A1
    - Royal Victoria Hospital - Montreal
  - Montreal, Quebec, Canada, H2L 4M1
    - Hopital Notre-Dame du CHUM
  - Montreal, Quebec, Canada, H2X 3J4
    - CHUM Hopital Saint-Luc
  - Quebec City, Quebec, Canada, G1S 4L8
    - Hopital du Saint-Sacrement, Quebec
- Saskatchewan
  - Regina, Saskatchewan, Canada, S4T 7T1
    - Allan Blair Cancer Centre at Pasqua Hospital
Forente stater
- Alabama
  - Anniston, Alabama, Forente stater, 36202
    - Northeast Alabama Regional Medical Center
  - Birmingham, Alabama, Forente stater, 35294
    - Comprehensive Cancer Center at University of Alabama at Birmingham
  - Huntsville, Alabama, Forente stater, 35801
    - Huntsville Hospital
  - Mobile, Alabama, Forente stater, 36652-2144
    - Mobile Infirmary Medical Center
  - Opelika, Alabama, Forente stater, 36801-5452
    - East Alabama Medical Center
- Alaska
  - Anchorage, Alaska, Forente stater, 99519-6604
    - Cancer Center at Providence Alaska Medical Center
  - Fairbanks, Alaska, Forente stater, 99701
    - Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital
- Arizona
  - Glendale, Arizona, Forente stater, 85306
    - Banner Thunderbird Medical Center
  - Phoenix, Arizona, Forente stater, 85006
    - Banner Good Samaritan Medical Center
  - Phoenix, Arizona, Forente stater, 85006
    - CCOP - Western Regional, Arizona
  - Scottsdale, Arizona, Forente stater, 85259
    - Mayo Clinic Scottsdale
  - Tucson, Arizona, Forente stater, 85724-5024
    - Arizona Cancer Center at University of Arizona Health Sciences Center
- Arkansas
  - Hot Springs, Arkansas, Forente stater, 71913
    - Saint Joseph's Mercy Cancer Center
- California
  - Berkeley, California, Forente stater, 94704
    - Alta Bates Comprehensive Cancer Center
  - Burbank, California, Forente stater, 91505
    - Providence Saint Joseph Medical Center - Burbank
  - Burlingame, California, Forente stater, 94010
    - Peninsula Medical Center
  - Concord, California, Forente stater, 94524-4110
    - Mount Diablo Regional Cancer Center
  - Duarte, California, Forente stater, 91010-3000
    - City of Hope Comprehensive Cancer Center
  - Fairfield, California, Forente stater, 94533
    - North Bay Cancer Center
  - Fremont, California, Forente stater, 94538
    - Kaiser Permanente - Fremont
  - Fremont, California, Forente stater, 94538
    - Washington Township Hospital
  - Fresno, California, Forente stater, 93720
    - California Cancer Center - Woodward Park Office
  - Fullerton, California, Forente stater, 92835
    - Virginia K. Crosson Cancer Center at St. Jude Medical Center
  - Glendale, California, Forente stater, 91204
    - Glendale Memorial Hospital Comprehensive Cancer Center
  - Greenbrae, California, Forente stater, 94904
    - Marin Cancer Institute at Marin General Hospital
  - Greenbrae, California, Forente stater, 94904
    - Sutter Health - Western Division Cancer Research Group
  - Hayward, California, Forente stater, 94545
    - Saint Rose Hospital
  - Hayward, California, Forente stater, 94545
    - Kaiser Permanente Medical Center - Hayward
  - La Jolla, California, Forente stater, 92093-0658
    - Moores UCSD Cancer Center
  - La Jolla, California, Forente stater, 92037
    - Scripps Cancer Center at Scripps Clinic
  - La Jolla, California, Forente stater, 92037-1276
    - Stevens Cancer Center at Scripps Memorial Hospital
  - Loma Linda, California, Forente stater, 92354
    - Loma Linda University Cancer Institute at Loma Linda University Medical Center
  - Long Beach, California, Forente stater, 90813
    - Pacific Shores Medical Group Comprehensive Hematology-Oncology Services - Long Beach
  - Los Angeles, California, Forente stater, 90095-1781
    - Jonsson Comprehensive Cancer Center at UCLA
  - Los Angeles, California, Forente stater, 90089-9181
    - USC/Norris Comprehensive Cancer Center and Hospital
  - Mission Hills, California, Forente stater, 91346-9600
    - Providence Holy Cross Cancer Center
  - Modesto, California, Forente stater, 95355
    - Memorial Medical Center Cancer Services
  - Oakland, California, Forente stater, 94609
    - Alta Bates Summit Medical Center - Summit Campus
  - Oakland, California, Forente stater, 94609
    - CCOP - Bay Area Tumor Institute
  - Oakland, California, Forente stater, 94611
    - Kaiser Permanente Medical Center - Oakland
  - Oakland, California, Forente stater, 94602
    - Highland General Hospital at St. George's University School of Medicine
  - Orange, California, Forente stater, 92868
    - Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center
  - Palm Springs, California, Forente stater, 92262
    - Desert Regional Medical Center Comprehensive Cancer Center
  - Pleasanton, California, Forente stater, 94588
    - Valley Care Medical Center
  - Pomona, California, Forente stater, 91767
    - Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center
  - Redwood City, California, Forente stater, 94063
    - Kaiser Permanente Medical Center - Redwood City
  - Richmond, California, Forente stater, 94801
    - Kaiser Permanente Medical Center - Richmond
  - Roseville, California, Forente stater, 95661
    - Kaiser Permanente Medical Center - Roseville
  - Roseville, California, Forente stater, 95661
    - Sutter Cancer Center at Roseville Medical Center
  - Sacramento, California, Forente stater, 95816
    - Sutter Cancer Center
  - Sacramento, California, Forente stater, 95819
    - Mercy General Hospital
  - Sacramento, California, Forente stater, 95823
    - South Sacramento Kaiser-Permanente Medical Center
  - Sacramento, California, Forente stater, 95825
    - Kaiser Permanente Medical Center - Sacramento
  - Salinas, California, Forente stater, 93901
    - Salinas Valley Memorial Hospital
  - San Francisco, California, Forente stater, 94115
    - Kaiser Permanente Medical Center - San Francisco Geary Campus
  - San Francisco, California, Forente stater, 94118
    - California Pacific Medical Center - California Campus
  - San Jose, California, Forente stater, 95119
    - Kaiser Permanente Medical Center - Santa Teresa
  - San Pablo, California, Forente stater, 94806
    - J.C. Robinson, M.D. Regional Cancer Center
  - San Rafael, California, Forente stater, 94903
    - Kaiser Foundation Hospital - San Rafael
  - Santa Clara, California, Forente stater, 95051
    - Kaiser Permanente Medical Center - Santa Clara Kiely Campus
  - Santa Rosa, California, Forente stater, 95403
    - Kaiser Permanente Medical Center - Santa Rosa
  - Santa Rosa, California, Forente stater, 95405
    - CCOP - Santa Rosa Memorial Hospital
  - South San Francisco, California, Forente stater, 94080
    - Kaiser Permanente Medical Center - South San Francisco
  - Stanford, California, Forente stater, 94305
    - Stanford Cancer Center at Stanford University Medical Center
  - Stockton, California, Forente stater, 95210
    - Kaiser Permanente Medical Facility - Stockton
  - Torrance, California, Forente stater, 90509
    - Torrance Memorial Medical Center
  - Vallejo, California, Forente stater, 94589
    - Sutter Solano Medical Center
  - Vallejo, California, Forente stater, 94589
    - Kaiser Permanente Medical Center - Vallejo
  - Walnut Creek, California, Forente stater, 94596
    - Kaiser Permanente Medical Center - Walnut Creek
  - Walnut Creek, California, Forente stater, 94598
    - John Muir/Mt. Diablo Comprehensive Cancer Center
  - Whittier, California, Forente stater, 90602
    - Ruby L. Golleher Cancer Program at Presbyterian Intercommunity Hospital
- Colorado
  - Aurora, Colorado, Forente stater, 80012
    - Aurora Presbyterian Hospital
  - Boulder, Colorado, Forente stater, 80301-9019
    - Boulder Community Hospital
  - Colorado Springs, Colorado, Forente stater, 80933
    - Penrose Cancer Center at Penrose Hospital
  - Colorado Springs, Colorado, Forente stater, 80909
    - Memorial Hospital
  - Denver, Colorado, Forente stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forente stater, 80220
    - Rose Medical Center
  - Denver, Colorado, Forente stater, 80218
    - Presbyterian - St. Luke's Medical Center
  - Denver, Colorado, Forente stater, 80218
    - St. Joseph Hospital
  - Denver, Colorado, Forente stater, 80224-2522
    - CCOP - Colorado Cancer Research Program, Incorporated
  - Englewood, Colorado, Forente stater, 80110
    - Swedish Medical Center
  - Fort Collins, Colorado, Forente stater, 80524
    - Poudre Valley Hospital
  - Fort Collins, Colorado, Forente stater, 80524
    - Front Range Cancer Specialists
  - Grand Junction, Colorado, Forente stater, 81502
    - St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
  - Greeley, Colorado, Forente stater, 80631
    - North Colorado Medical Center
  - Lone Tree, Colorado, Forente stater, 80124
    - Sky Ridge Medical Center
  - Longmont, Colorado, Forente stater, 80502
    - Hope Cancer Care Center at Longmont United Hospital
  - Loveland, Colorado, Forente stater, 80539
    - McKee Medical Center
  - Pueblo, Colorado, Forente stater, 81004
    - St. Mary-Corwin Regional Medical Center
  - Thornton, Colorado, Forente stater, 80229
    - North Suburban Medical Center
- Connecticut
  - Bridgeport, Connecticut, Forente stater, 06610
    - Bridgeport Hospital
  - Danbury, Connecticut, Forente stater, 06810
    - Praxair Cancer Center at Danbury Hospital
  - Hartford, Connecticut, Forente stater, 06102-5037
    - Helen and Harry Gray Cancer Center at Hartford Hospital
  - Middletown, Connecticut, Forente stater, 06457
    - Middlesex Hospital Cancer Center
  - Stamford, Connecticut, Forente stater, 06904
    - Carl and Dorothy Bennett Cancer Center at Stamford Hospital
  - Waterbury, Connecticut, Forente stater, 06708
- Delaware
  - Lewes, Delaware, Forente stater, 19958
    - Beebe Medical Center
  - Newark, Delaware, Forente stater, 19713
    - CCOP - Christiana Care Health Services
  - Wilmington, Delaware, Forente stater, 19805
    - St. Francis Hospital
- District of Columbia
  - Washington, District of Columbia, Forente stater, 20007
    - Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
  - Washington, District of Columbia, Forente stater, 20016
    - Sibley Memorial Hospital
  - Washington, District of Columbia, Forente stater, 20010
    - Washington Cancer Institute at Washington Hospital Center
- Florida
  - Boca Raton, Florida, Forente stater, 33486
    - Lynn Regional Cancer Center at Boca Raton Community Hospital - Main Center
  - Clearwater, Florida, Forente stater, 33756
    - Morton Plant Hospital
  - Daytona Beach, Florida, Forente stater, 32115
    - Halifax Medical Center
  - Fort Lauderdale, Florida, Forente stater, 33316
    - Broward General Medical Center Cancer Center
  - Fort Lauderdale, Florida, Forente stater, 33308
    - Michael & Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
  - Gainesville, Florida, Forente stater, 32610-0232
    - University of Florida Shands Cancer Center
  - Hollywood, Florida, Forente stater, 33021
    - Memorial Cancer Institute at Memorial Regional Hospital
  - Jacksonville, Florida, Forente stater, 32204
    - St. Vincent's Medical Center
  - Jacksonville, Florida, Forente stater, 32224
    - Mayo Clinic - Jacksonville
  - Jacksonville, Florida, Forente stater, 32207
    - Baptist Cancer Institute - Jacksonville
  - Jupiter, Florida, Forente stater, 33458
    - Ella Milbank Foshay Cancer Center at Jupiter Medical Center
  - Lakeland, Florida, Forente stater, 33805
    - Lakeland Regional Cancer Center at Lakeland Regional Medical Center
  - Lakeland, Florida, Forente stater, 33804-5000
    - Watson Clinic, LLC
  - Miami, Florida, Forente stater, 33136
    - University of Miami Sylvester Comprehensive Cancer Center
  - Miami Beach, Florida, Forente stater, 33140
    - CCOP - Mount Sinai Medical Center
  - Orlando, Florida, Forente stater, 32806
    - M.D. Anderson Cancer Center - Orlando
  - Sarasota, Florida, Forente stater, 34231
    - Florida Cancer Specialists - Sarasota Downtown
  - Stuart, Florida, Forente stater, 34994
    - Robert and Carol Weissman Cancer Center at Martin Memorial
- Georgia
  - Albany, Georgia, Forente stater, 31701
    - Phoebe Cancer Center at Phoebe Putney Memorial Hospital
  - Athens, Georgia, Forente stater, 30607
    - Northeast Georgia Cancer Care, LLC
  - Atlanta, Georgia, Forente stater, 30322
    - Winship Cancer Institute of Emory University
  - Atlanta, Georgia, Forente stater, 30309
    - Piedmont Hospital
  - Atlanta, Georgia, Forente stater, 30342-1611
    - Northside Hospital Cancer Center
  - Atlanta, Georgia, Forente stater, 30342-1701
    - Saint Joseph's Hospital of Atlanta
  - Atlanta, Georgia, Forente stater, 30342
    - CCOP - Atlanta Regional
  - Atlanta, Georgia, Forente stater, 30308
    - Emory Crawford Long Hospital
  - Augusta, Georgia, Forente stater, 30912
    - MBCCOP-Medical College of Georgia Cancer Center
  - Augusta, Georgia, Forente stater, 30901
    - Augusta Oncology Associates - Walton Way
  - Austell, Georgia, Forente stater, 30106
    - WellStar Cobb Hospital
  - Columbus, Georgia, Forente stater, 31904
    - John B. Amos Community Cancer Center
  - Decatur, Georgia, Forente stater, 30033
    - Charles B. Eberhart Cancer Center at DeKalb Medical Center
  - Gainesville, Georgia, Forente stater, 30501
    - Northeast Georgia Medical Center
  - Lawrenceville, Georgia, Forente stater, 30045
    - Gwinnett Medical Center
  - Macon, Georgia, Forente stater, 31208
    - Medical Center of Central Georgia
  - Marietta, Georgia, Forente stater, 30060
    - Kennestone Cancer Center at Wellstar Kennestone Hospital
  - Riverdale, Georgia, Forente stater, 30274-2600
    - Southern Regional Medical Center
  - Savannah, Georgia, Forente stater, 31403-3089
    - Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
  - Savannah, Georgia, Forente stater, 31405
    - Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
- Hawaii
  - Honolulu, Hawaii, Forente stater, 96813
    - Cancer Research Center of Hawaii
- Idaho
  - Boise, Idaho, Forente stater, 83706
    - Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
  - Boise, Idaho, Forente stater, 83712
    - St. Luke's Mountain States Tumor Institute - Boise
  - Idaho Falls, Idaho, Forente stater, 83404
    - Hematology Oncology Associates of Eastern Idaho
  - Pocatello, Idaho, Forente stater, 83201
    - Portneuf Cancer Center at Portneuf Medical Center
- Illinois
  - Alton, Illinois, Forente stater, 62002
    - Saint Anthony's Hospital at Saint Anthony's Health Center
  - Aurora, Illinois, Forente stater, 60507
    - Rush-Copley Cancer Care Center
  - Bloomington, Illinois, Forente stater, 61701
    - St. Joseph Medical Center
  - Canton, Illinois, Forente stater, 61520
    - Graham Hospital
  - Carthage, Illinois, Forente stater, 62321
    - Memorial Hospital
  - Chicago, Illinois, Forente stater, 60612
    - Rush University Medical Center
  - Chicago, Illinois, Forente stater, 60611-3013
    - Robert H. Lurie Comprehensive Cancer Center at Northwestern University
  - Chicago, Illinois, Forente stater, 60625
    - Swedish Covenant Hospital
  - Chicago, Illinois, Forente stater, 60657
    - Creticos Cancer Center at Advocate Illinois Masonic Medical Center
  - Chicago, Illinois, Forente stater, 60631
    - Resurrection Medical Center
  - Chicago, Illinois, Forente stater, 60616
    - Mercy Hospital and Medical Center
  - Decatur, Illinois, Forente stater, 62526
    - Decatur Memorial Hospital Cancer Care Institute
  - Elgin, Illinois, Forente stater, 60120
    - Sherman Hospital
  - Elk Grove Village, Illinois, Forente stater, 60007
    - Alexian Brothers Radiation Oncology
  - Elmhurst, Illinois, Forente stater, 60126
    - Elmhurst Memorial Hospital
  - Eureka, Illinois, Forente stater, 61530
    - Eureka Community Hospital
  - Evanston, Illinois, Forente stater, 60201-1781
    - Evanston Northwestern Health Care - Evanston Hospital
  - Galesburg, Illinois, Forente stater, 61401
    - Galesburg Cottage Hospital
  - Galesburg, Illinois, Forente stater, 61401
    - Galesburg Clinic
  - Galesburg, Illinois, Forente stater, 61401
    - Medical and Surgical Specialists, L L C
  - Galesburg, Illinois, Forente stater, 61401
    - InterCommunity Cancer Center of Western Illinois
  - Geneva, Illinois, Forente stater, 60134
    - Delnor Community Hospital - Geneva
  - Harvey, Illinois, Forente stater, 60426
    - Ingalls Cancer Care Center at Ingalls Memorial Hospital
  - Havana, Illinois, Forente stater, 62644
    - Mason District Hospital
  - Hinsdale, Illinois, Forente stater, 60521
    - Hinsdale Hematology Oncology Associates
  - Hopedale, Illinois, Forente stater, 61747
    - Hopedale Medical Complex
  - Joliet, Illinois, Forente stater, 60435
    - Joliet Oncology-Hematology Associates, Limited - West
  - Kankakee, Illinois, Forente stater, 60901
    - Provena St. Mary's Wasser Regional Cancer Center - Kankakee
  - Kewanee, Illinois, Forente stater, 61443
    - Kewanee Hospital
  - Macomb, Illinois, Forente stater, 61455
    - Mcdonough District Hospital
  - Maywood, Illinois, Forente stater, 60153
    - Cardinal Bernardin Cancer Center at Loyola University Medical Center
  - Moline, Illinois, Forente stater, 61265
    - Trinity Medical Center - East
  - Mount Vernon, Illinois, Forente stater, 62864
    - Good Samaritan Regional Health Center
  - Naperville, Illinois, Forente stater, 60540
    - Edward Hospital Cancer Center
  - Normal, Illinois, Forente stater, 61761
    - Bromenn Regional Medical Center
  - Normal, Illinois, Forente stater, 61761
    - Community Cancer Center
  - Oak Lawn, Illinois, Forente stater, 60453-2699
    - Advocate Christ Medical Center
  - Olympia Fields, Illinois, Forente stater, 60461
    - Saint James Hospital and Health Centers Comprehensive Cancer Institute - Olympia Fields
  - Ottawa, Illinois, Forente stater, 61350
    - Community Hospital of Ottawa
  - Park Ridge, Illinois, Forente stater, 60068
    - Lutheran General Cancer Care Center
  - Pekin, Illinois, Forente stater, 61554
    - Cancer Treatment Center at Pekin Hospital
  - Peoria, Illinois, Forente stater, 61636
    - Methodist Medical Center of Illinois
  - Peoria, Illinois, Forente stater, 61614
    - Proctor Hospital
  - Peoria, Illinois, Forente stater, 61637
    - OSF St. Francis Medical Center
  - Peoria, Illinois, Forente stater, 61615
    - CCOP - Illinois Oncology Research Association
  - Peoria, Illinois, Forente stater, 61615
    - Oncology Hematology Associates of Central Illinois, PC - Peoria
  - Peru, Illinois, Forente stater, 61354
    - Illinois Valley Community Hospital
  - Princeton, Illinois, Forente stater, 61356
    - Perry Memorial Hospital
  - Rockford, Illinois, Forente stater, 61104-2315
    - Swedish-American Regional Cancer Center
  - Rockford, Illinois, Forente stater, 61108
    - Center for Cancer Care at OSF Saint Anthony Medical Center
  - Skokie, Illinois, Forente stater, 60076
    - Hematology/Oncology of the North Shore at Gross Point Medical Center
  - Spring Valley, Illinois, Forente stater, 61362
    - St. Margaret's Hospital
  - Spring Valley, Illinois, Forente stater, 61362
    - Valley Cancer Center
  - Springfield, Illinois, Forente stater, 62781
    - Regional Cancer Center at Memorial Medical Center
  - Urbana, Illinois, Forente stater, 61801
    - Carle Cancer Center at Carle Foundation Hospital
  - Urbana, Illinois, Forente stater, 61801
    - CCOP - Carle Cancer Center
- Indiana
  - Beech Grove, Indiana, Forente stater, 46107
    - St. Francis Hospital and Health Centers - Beech Grove Campus
  - Bloomington, Indiana, Forente stater, 47403
    - Regional Cancer Institute at Bloomington Hospital
  - Elkhart, Indiana, Forente stater, 46515
    - Elkhart General Hospital
  - Goshen, Indiana, Forente stater, 46527
    - Center for Cancer Care at Goshen Health System
  - Indianapolis, Indiana, Forente stater, 46202
    - Methodist Cancer Center at Clarian Health
  - Kokomo, Indiana, Forente stater, 46904
    - Howard Community Hospital at Howard Regional Health System
  - La Porte, Indiana, Forente stater, 46350
    - Center for Cancer Therapy at LaPorte Hospital and Health Services
  - Lafayette, Indiana, Forente stater, 47904
    - Arnett Cancer Care
  - Michigan City, Indiana, Forente stater, 46360
    - Saint Anthony Memorial Health Centers
  - Munster, Indiana, Forente stater, 46321
    - Community Hospital
  - South Bend, Indiana, Forente stater, 46601
    - Memorial Hospital of South Bend
  - South Bend, Indiana, Forente stater, 46601
    - CCOP - Northern Indiana CR Consortium
- Iowa
  - Ames, Iowa, Forente stater, 50010
    - McFarland Clinic, P. C.
  - Cedar Rapids, Iowa, Forente stater, 52402
    - St. Luke's Hospital
  - Cedar Rapids, Iowa, Forente stater, 52403
    - Cedar Rapids Oncology Associates
  - Cedar Rapids, Iowa, Forente stater, 52403
    - Mercy Regional Cancer Center at Mercy Medical Center
  - Cedar Rapids, Iowa, Forente stater, 52402
    - Iowa Blood and Cancer Care
  - Davenport, Iowa, Forente stater, 52803
    - Genesis Regional Cancer Center at Genesis Medical Center
  - Des Moines, Iowa, Forente stater, 50309
    - CCOP - Iowa Oncology Research Association
  - Des Moines, Iowa, Forente stater, 50309
    - John Stoddard Cancer Center at Iowa Methodist Medical Center
  - Des Moines, Iowa, Forente stater, 50309
    - Medical Oncology and Hematology Associates at John Stoddard Cancer Center
  - Des Moines, Iowa, Forente stater, 50314
    - Medical Oncology and Hematology Associates at Mercy Cancer Center
  - Des Moines, Iowa, Forente stater, 50314
    - Mercy Cancer Center at Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forente stater, 50307
    - Mercy Capitol Hospital
  - Des Moines, Iowa, Forente stater, 50316-2301
    - John Stoddard Cancer Center at Iowa Lutheran Hospital
  - Dubuque, Iowa, Forente stater, 52001
    - Wendt Regional Cancer Center at Finley Hospital
  - Iowa City, Iowa, Forente stater, 52242
    - Holden Comprehensive Cancer Center at University of Iowa
  - Mason City, Iowa, Forente stater, 50401
    - Mercy Cancer Center at Mercy Medical Center - North Iowa
  - Ottumwa, Iowa, Forente stater, 52501
    - Ottumwa Regional Health Center Cancer Center
  - Sioux City, Iowa, Forente stater, 51101
    - Siouxland Regional Cancer Center
  - Sioux City, Iowa, Forente stater, 51104
    - St. Luke's Regional Medical Center
  - Sioux City, Iowa, Forente stater, 51104
    - Mercy Medical Center - Sioux City
  - Sioux City, Iowa, Forente stater, 51101
    - Siouxland Hematology-Oncology Associates
  - Waterloo, Iowa, Forente stater, 50702
    - Covenant Cancer Treatment Center
  - Waterloo, Iowa, Forente stater, 50702
    - Cedar Valley Medical Specialists, P.C. - West Ridgeway Avenue
  - West Des Moines, Iowa, Forente stater, 50266
    - Medical Oncology and Hematology Associates - West Des Moines
- Kansas
  - Dodge City, Kansas, Forente stater, 67801
    - Cancer Center of Kansas, PA - Dodge City
  - El Dorado, Kansas, Forente stater, 67042
    - Cancer Center of Kansas, P.A. - El Dorado
  - Liberal, Kansas, Forente stater, 67901
    - Southwest Medical Center
  - Pittsburg, Kansas, Forente stater, 66762
    - Mount Carmel Regional Cancer Center
  - Topeka, Kansas, Forente stater, 66606
    - St. Francis Comprehensive Cancer Center
  - Topeka, Kansas, Forente stater, 66604
    - Stormont-Vail Cancer Center
  - Wellington, Kansas, Forente stater, 67152
    - Cancer Center of Kansas, P.A. - Wellington
  - Wichita, Kansas, Forente stater, 67214
    - Wesley Medical Center
  - Wichita, Kansas, Forente stater, 67214
    - CCOP - Wichita
  - Wichita, Kansas, Forente stater, 67214
    - Via Christi Cancer Center at Via Christi Regional Medical Center
  - Wichita, Kansas, Forente stater, 67203
    - Associates in Womens Health, P.A. - North Review
  - Winfield, Kansas, Forente stater, 67156
    - Cancer Center of Kansas, P.A. - Winfield
- Kentucky
  - Ashland, Kentucky, Forente stater, 41101
    - Cancer Resource Center at King's Daughters Medical Center
  - Lexington, Kentucky, Forente stater, 40503-9985
    - Central Baptist Hospital
  - Lexington, Kentucky, Forente stater, 40536-0293
    - Markey Cancer Center at University of Kentucky Chandler Medical Center
  - Lexington, Kentucky, Forente stater, 40504
    - Lexington Clinic Cancer Center
  - Louisville, Kentucky, Forente stater, 40207
    - Baptist Hospital East - Louisville
  - Louisville, Kentucky, Forente stater, 40202
    - Louisville Oncology at Norton Cancer Center
  - Louisville, Kentucky, Forente stater, 40202
    - James Graham Brown Cancer Center at University of Louisville
  - Madisonville, Kentucky, Forente stater, 42431
    - Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County
- Louisiana
  - Baton Rouge, Louisiana, Forente stater, 708169990
    - Ochsner Clinic of Baton Rouge
  - Houma, Louisiana, Forente stater, 70360
    - Terrebonne General Medical Center
  - New Orleans, Louisiana, Forente stater, 70121
    - CCOP - Ochsner
  - Shreveport, Louisiana, Forente stater, 71130-3932
    - Feist-Weiller Cancer Center at Louisiana State University Health Sciences
  - Shreveport, Louisiana, Forente stater, 71101
    - Veterans Affairs Medical Center - Shreveport
  - Shreveport, Louisiana, Forente stater, 71101
    - Cancer Treatment Center at Christus Schumpert St. Mary Place
- Maine
  - Bangor, Maine, Forente stater, 04401
    - CancerCare of Maine at Eastern Maine Medial Center
  - Lewiston, Maine, Forente stater, 04240
    - Central Maine Medical Center
  - Waterville, Maine, Forente stater, 04901
    - MaineGeneral Medical Center - Waterville Campus
- Maryland
  - Annapolis, Maryland, Forente stater, 21401
    - DeCesaris Cancer Institute at Anne Arundel Medical Center
  - Baltimore, Maryland, Forente stater, 21204
    - Greater Baltimore Medical Center
  - Baltimore, Maryland, Forente stater, 21202
    - Mercy Medical Center
  - Baltimore, Maryland, Forente stater, 21201
    - Greenebaum Cancer Center at University of Maryland Medical Center
  - Baltimore, Maryland, Forente stater, 21237
    - Harry and Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
  - Baltimore, Maryland, Forente stater, 21229
    - St. Agnes Cancer Center
  - Bethesda, Maryland, Forente stater, 20889
    - National Naval Medical Center
  - Bethesda, Maryland, Forente stater, 20814
    - Suburban Hospital
  - Easton, Maryland, Forente stater, 21601
    - Shore Regional Cancer Center at Memorial Hospital - Easton
  - Elkton, Maryland, Forente stater, 21921
    - Union Hospital Cancer Center at Union Hospital
  - Frederick, Maryland, Forente stater, 21701
    - Frederick Memorial Hospital Regional Cancer Therapy Center
  - Leonardtown, Maryland, Forente stater, 20650
    - St. Mary's Hospital
  - Rockville, Maryland, Forente stater, 20850
    - Kaiser Permanente Capital Area Medical Group - Shady Grove Facility
  - Silver Spring, Maryland, Forente stater, 20910
    - Holy Cross Hospital
  - Towson, Maryland, Forente stater, 21204
    - Cancer Institute at St. Joseph Medical Center
- Massachusetts
  - Attleboro, Massachusetts, Forente stater, 02703
    - Sturdy Memorial Hospital
  - Boston, Massachusetts, Forente stater, 02215
    - Beth Israel Deaconess Medical Center
  - Boston, Massachusetts, Forente stater, 02115
    - Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute
  - Boston, Massachusetts, Forente stater, 02118
    - Cancer Research Center at Boston Medical Center
  - Boston, Massachusetts, Forente stater, 02111
    - TUFTS - New England Medical Center
  - Boston, Massachusetts, Forente stater, 02135-2997
    - Caritas St. Elizabeth's Medical Center
  - Burlington, Massachusetts, Forente stater, 01805
    - Lahey Clinic Medical Center - Burlington
  - Fall River, Massachusetts, Forente stater, 02721
    - Hudner Oncology Center at Saint Anne's Hospital
  - Framingham, Massachusetts, Forente stater, 01702
    - Metrowest Medical Center - Framingham Union Hospital
  - Greenfield, Massachusetts, Forente stater, 01301
    - Franklin Medical Center
  - Medford, Massachusetts, Forente stater, 02155
    - Lawrence Memorial Hospital of Medford
  - Methuen, Massachusetts, Forente stater, 01844
    - Caritas Holy Family Hospital
  - Newton, Massachusetts, Forente stater, 02462
    - Newton-Wellesley Hospital
  - Norwood, Massachusetts, Forente stater, 02062
    - Caritas Norwood Hospital
  - Peabody, Massachusetts, Forente stater, 01960
    - NSMC Cancer Center - Peabody
  - Pittsfield, Massachusetts, Forente stater, 01201
    - Berkshire Medical Center
  - Plymouth, Massachusetts, Forente stater, 02360
    - Jordan Hospital Club Cancer Center
  - Quincy, Massachusetts, Forente stater, 02169
    - Commonwealth Hematology-Oncology P. C. - Quincy
  - South Weymouth, Massachusetts, Forente stater, 02190
    - South Shore Hospital
  - Springfield, Massachusetts, Forente stater, 01199
    - Baystate Regional Cancer Program at D'Amour Center for Cancer Care
  - Worcester, Massachusetts, Forente stater, 01655
    - UMASS Memorial Cancer Center - University Campus
- Michigan
  - Adrian, Michigan, Forente stater, 49221
    - Hickman Cancer Center at Bixby Medical Center
  - Ann Arbor, Michigan, Forente stater, 48109-0942
    - University of Michigan Comprehensive Cancer Center
  - Ann Arbor, Michigan, Forente stater, 48106
    - CCOP - Michigan Cancer Research Consortium
  - Ann Arbor, Michigan, Forente stater, 48106-0995
    - St. Joseph Mercy Cancer Center at St. Joseph Mercy Hospital
  - Battle Creek, Michigan, Forente stater, 49017
    - Battle Creek Health System Cancer Care Center
  - Bay City, Michigan, Forente stater, 48708
    - Bay Regional Medical Center
  - Big Rapids, Michigan, Forente stater, 49307
    - Mecosta County Medical Center
  - Dearborn, Michigan, Forente stater, 48123-2500
    - Oakwood Cancer Center at Oakwood Hospital and Medical Center
  - Detroit, Michigan, Forente stater, 48202
    - Josephine Ford Cancer Center at Henry Ford Hospital
  - Escanaba, Michigan, Forente stater, 49431
    - Green Bay Oncology, Limited - Escanaba
  - Flint, Michigan, Forente stater, 48503
    - Hurley Medical Center
  - Flint, Michigan, Forente stater, 48503
    - Genesys Hurley Cancer Institute
  - Flint, Michigan, Forente stater, 48532
    - Great Lakes Cancer Institute at McLaren Regional Medical Center
  - Grand Rapids, Michigan, Forente stater, 49503
    - CCOP - Grand Rapids
  - Grand Rapids, Michigan, Forente stater, 49503
    - Lacks Cancer Center at Saint Mary's Mercy Medical Center
  - Grand Rapids, Michigan, Forente stater, 49503
    - Spectrum Health Cancer Care - Butterworth Campus
  - Grand Rapids, Michigan, Forente stater, 49506
    - Metropolitan Hospital
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Van Elslander Cancer Center at St. John Hospital and Medical Center
  - Holland, Michigan, Forente stater, 49423
    - Holland Community Hospital
  - Iron Mountain, Michigan, Forente stater, 49801
    - Green Bay Oncology, Limited - Iron Mountain
  - Jackson, Michigan, Forente stater, 49201
    - Foote Hospital
  - Kalamazoo, Michigan, Forente stater, 49007
    - Bronson Methodist Hospital
  - Kalamazoo, Michigan, Forente stater, 49001
    - Borgess Medical Center
  - Kalamazoo, Michigan, Forente stater, 49007-3731
    - West Michigan Cancer Center
  - Lansing, Michigan, Forente stater, 48910
    - Breslin Cancer Center at Ingham Regional Medical Center
  - Lansing, Michigan, Forente stater, 48909
    - Sparrow Regional Cancer Center
  - Marquette, Michigan, Forente stater, 49855
    - Upper Michigan Cancer Center at Marquette General Hospital
  - Midland, Michigan, Forente stater, 48670
    - MidMichigan Medical Center - Midland
  - Monroe, Michigan, Forente stater, 48162
    - Mercy Memorial Hospital System
  - Mount Clemens, Michigan, Forente stater, 48043
    - Ted B. Wahby Cancer Center at Mount Clemens General Hospital
  - Muskegon, Michigan, Forente stater, 49443
    - Hackley Hospital
  - Petoskey, Michigan, Forente stater, 49770
    - Northern Michigan Hospital
  - Pontiac, Michigan, Forente stater, 48341-2985
    - St. Joseph Mercy Hospital
  - Royal Oak, Michigan, Forente stater, 48073
    - William Beaumont Hospital - Royal Oak Campus
  - Saginaw, Michigan, Forente stater, 48601
    - Seton Cancer Institute - Saginaw
  - Saint Joseph, Michigan, Forente stater, 49085
    - Lakeland Cancer Care Center at Lakeland Hospital - St. Joseph
  - Saint Joseph, Michigan, Forente stater, 49085
    - Oncology Care Associates, PLLC
  - Southfield, Michigan, Forente stater, 48075
    - Providence Cancer Institute at Providence Hospital - Southfield Campus
  - Traverse City, Michigan, Forente stater, 49684
    - Munson Medical Center
  - Warren, Michigan, Forente stater, 48093
    - St. John Macomb Hospital
- Minnesota
  - Albert Lea, Minnesota, Forente stater, 56007
    - Albert Lea Cancer Center at Albert Lea Medical Center
  - Bemidji, Minnesota, Forente stater, 56601
    - MeritCare Clinic - Bemidji
  - Burnsville, Minnesota, Forente stater, 55337
    - Fairview Ridges Hospital
  - Coon Rapids, Minnesota, Forente stater, 55433
    - Mercy and Unity Cancer Center at Mercy Hospital
  - Duluth, Minnesota, Forente stater, 55805
    - CCOP - Duluth
  - Duluth, Minnesota, Forente stater, 55805
    - St. Mary's - Duluth Clinic Cancer Center
  - Duluth, Minnesota, Forente stater, 55805
    - Miller-Dwan Medical Center
  - Duluth, Minnesota, Forente stater, 55805
    - Cancer Care Center at St. Luke's Hospital
  - Edina, Minnesota, Forente stater, 55435
    - Fairview Southdale Hospital
  - Fridley, Minnesota, Forente stater, 55432
    - Mercy and Unity Cancer Center at Unity Hospital
  - Hutchinson, Minnesota, Forente stater, 55350
    - Hutchinson Area Health Care
  - Litchfield, Minnesota, Forente stater, 55355
    - Meeker County Memorial Hospital
  - Maplewood, Minnesota, Forente stater, 55109
    - HealthEast Cancer Care at St. John's Hospital
  - Minneapolis, Minnesota, Forente stater, 55415
    - Hennepin County Medical Center - Minneapolis
  - Minneapolis, Minnesota, Forente stater, 55407
    - Virginia Piper Cancer Institute at Abbott-Northwestern Hospital
  - Robbinsdale, Minnesota, Forente stater, 55422-2900
    - Hubert H. Humphrey Cancer Center at North Memorial Medical Center
  - Rochester, Minnesota, Forente stater, 55905
    - Mayo Clinic Cancer Center
  - Saint Cloud, Minnesota, Forente stater, 56303
    - CentraCare Clinic - River Campus
  - Saint Louis Park, Minnesota, Forente stater, 55416
    - CCOP - Metro-Minnesota
  - Saint Louis Park, Minnesota, Forente stater, 55416
    - Park Nicollet Health Services
  - Saint Paul, Minnesota, Forente stater, 55102
    - St. Joseph's Hospital
  - Saint Paul, Minnesota, Forente stater, 55102
    - United Hospital
  - Saint Paul, Minnesota, Forente stater, 55101
    - Regions Hospital Cancer Care Center
  - Shakopee, Minnesota, Forente stater, 55379
    - Saint Francis Cancer Center
  - Waconia, Minnesota, Forente stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forente stater, 56201
    - Rice Memorial Hospital
  - Woodbury, Minnesota, Forente stater, 55125
    - Woodwinds Health Campus
- Mississippi
  - Hattiesburg, Mississippi, Forente stater, 39401
    - Hattiesburg Clinic, P.A.
  - Jackson, Mississippi, Forente stater, 39216
    - University of Mississippi Medical Center
  - Pascagoula, Mississippi, Forente stater, 39581
    - Regional Cancer Center at Singing River Hospital
- Missouri
  - Cape Girardeau, Missouri, Forente stater, 63701
    - Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital
  - Cape Girardeau, Missouri, Forente stater, 63701
    - Saint Francis Medical Center
  - Columbia, Missouri, Forente stater, 65203
    - Ellis Fischel Cancer Center at University of Missouri - Columbia
  - Joplin, Missouri, Forente stater, 64804
    - St. John's Regional Medical Center
  - Joplin, Missouri, Forente stater, 64804
    - Freeman Cancer Institute at Freeman Health System
  - Kansas City, Missouri, Forente stater, 64131
    - CCOP - Kansas City
  - Saint Louis, Missouri, Forente stater, 63131
    - Missouri Baptist Cancer Center
  - Saint Louis, Missouri, Forente stater, 63141
    - CCOP - St. Louis-Cape Girardeau
  - Saint Louis, Missouri, Forente stater, 63110
    - Saint Louis University Cancer Center
  - Saint Louis, Missouri, Forente stater, 63141
    - David C. Pratt Cancer Center at St. John's Mercy
  - Saint Louis, Missouri, Forente stater, 63110
    - Siteman Cancer Center at Barnes-Jewish Hospital
  - Saint Louis, Missouri, Forente stater, 63141
    - Arch Medical Services, Incorporated at Center for Cancer Care Research
  - Saint Louis, Missouri, Forente stater, 63128
    - St. Anthony's Cancer Center
  - Springfield, Missouri, Forente stater, 65802
    - CCOP - Cancer Research for the Ozarks
  - Springfield, Missouri, Forente stater, 65804
    - St. John's Regional Health Center
  - Springfield, Missouri, Forente stater, 65807
    - Hulston Cancer Center at Cox Medical Center South
- Montana
  - Billings, Montana, Forente stater, 59101
    - CCOP - Montana Cancer Consortium
  - Billings, Montana, Forente stater, 59101
    - Northern Rockies Radiation Oncology Center
  - Billings, Montana, Forente stater, 59107-7000
    - Deaconess Billings Clinic - Downtown
  - Great Falls, Montana, Forente stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forente stater, 59405
    - Big Sky Oncology
  - Great Falls, Montana, Forente stater, 59405
    - Sletten Regional Cancer Institute
- Nebraska
  - Lincoln, Nebraska, Forente stater, 68510
    - Cancer Resource Center - Lincoln
  - Omaha, Nebraska, Forente stater, 68106
    - CCOP - Missouri Valley Cancer Consortium
  - Omaha, Nebraska, Forente stater, 68122
    - Immanuel Medical Center
  - Omaha, Nebraska, Forente stater, 68131-2197
    - Creighton University Medical Center
  - Omaha, Nebraska, Forente stater, 68124
    - Bergan Mercy Medical Center
  - Omaha, Nebraska, Forente stater, 68114
    - Methodist Cancer Center at Methodist Hospital - Omaha
- Nevada
  - Carson City, Nevada, Forente stater, 89703
    - Carson-Tahoe Cancer Services at Carson Tahoe Regional Healthcare
  - Las Vegas, Nevada, Forente stater, 89102
    - University Medical Center of Southern Nevada
  - Las Vegas, Nevada, Forente stater, 89106
    - CCOP - Nevada Cancer Research Foundation
  - Reno, Nevada, Forente stater, 89502
    - Washoe Cancer Services at Washoe Medical Center - Reno
- New Hampshire
  - Derry, New Hampshire, Forente stater, 03038
    - Parkland Oncology-Hematology Clinic at Parkland Medical Center
  - Dover, New Hampshire, Forente stater, 03820
    - Seacoast Cancer Center at Wentworth-Douglass Hospital
  - Exeter, New Hampshire, Forente stater, 03833
    - Exeter Hospital Center for Cancer Care
  - Hooksett, New Hampshire, Forente stater, 03106
    - New Hampshire Oncology-Hematology, PA - Hooksett
  - Laconia, New Hampshire, Forente stater, 03246
    - Lakes Region General Hospital
  - Manchester, New Hampshire, Forente stater, 03103
    - Elliot Regional Cancer Center
- New Jersey
  - Brick, New Jersey, Forente stater, 08724
    - Ocean Medical Center at Meridian Health
  - Englewood, New Jersey, Forente stater, 07631
    - Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center
  - Flemington, New Jersey, Forente stater, 08822
    - Hunterdon Regional Cancer Center at Hunterdon Medical Center
  - Hackensack, New Jersey, Forente stater, 07601
    - CCOP - Northern New Jersey
  - Hamilton, New Jersey, Forente stater, 08690
    - Cancer Institute of New Jersey at Hamilton
  - Livingston, New Jersey, Forente stater, 07039
    - St. Barnabas Medical Center
  - Long Branch, New Jersey, Forente stater, 07740-6395
    - Monmouth Medical Center
  - Marlton, New Jersey, Forente stater, 08053
    - Fox Chase Virtua Health Cancer Program - Marlton
  - Morristown, New Jersey, Forente stater, 07962
    - Carol G. Simon Cancer Center at Morristown Memorial Hospital
  - New Brunswick, New Jersey, Forente stater, 08903
    - Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
  - Newark, New Jersey, Forente stater, 07112
    - Newark Beth Israel Medical Center
  - Phillipsburg, New Jersey, Forente stater, 08865
    - Warren Hospital
  - Pomona, New Jersey, Forente stater, 08240
    - Atlanticare Regional Medical Center
  - Red Bank, New Jersey, Forente stater, 07701
    - Booker Cancer Center at Riverview Medical Center
  - Ridgewood, New Jersey, Forente stater, 07450
    - Valley Hospital - Ridgewood
  - Trenton, New Jersey, Forente stater, 08629
    - Fox Chase Cancer Center at St. Francis Medical Center
  - Trenton, New Jersey, Forente stater, 08618
    - Capital Health System Regional Cancer Center
  - Vineland, New Jersey, Forente stater, 08360
    - South Jersey Healthcare Regional Cancer Center
  - Voorhees, New Jersey, Forente stater, 08043
    - Cancer Institute of New Jersey at Cooper - Voorhees
  - Woodbury, New Jersey, Forente stater, 08096
    - Underwood Memorial Hospital
- New Mexico
  - Albuquerque, New Mexico, Forente stater, 87131-5636
    - University of New Mexico Cancer Research and Treatment Center
  - Albuquerque, New Mexico, Forente stater, 87106
    - Hematology Oncology Associates, PC
  - Albuquerque, New Mexico, Forente stater, 87108
    - Lovelace Medical Center
  - Santa Fe, New Mexico, Forente stater, 87505
    - New Mexico Cancer Care Associates
  - Santa Fe, New Mexico, Forente stater, 87505
    - Santa Fe Cancer Center at St. Vincent Hospital
- New York
  - Albany, New York, Forente stater, 12208
    - Albany Medical Center Hospital
  - Albany, New York, Forente stater, 12208
    - New York Oncology Hematology, PC at Albany Regional Cancer Care
  - Amsterdam, New York, Forente stater, 12010
    - Amsterdam Community Cancer Program
  - Bronx, New York, Forente stater, 10461
    - Albert Einstein Cancer Center at Albert Einstein College of Medicine
  - Bronx, New York, Forente stater, 10466
    - Our Lady of Mercy Medical Center Comprehensive Cancer Center
  - Elmira, New York, Forente stater, 14905
    - Falck Cancer Center at Arnot Ogden Medical Center
  - Glens Falls, New York, Forente stater, 12801
    - Charles R. Wood Cancer Center at Glens Falls Hospital
  - Hudson, New York, Forente stater, 12534
    - New York Oncology Hematology, P.C. at Cavell Cancer Treatment Program
  - Latham, New York, Forente stater, 12110
    - New York Oncology Hematology, P.C.
  - Manhasset, New York, Forente stater, 11030
    - CCOP - North Shore University Hospital
  - Manhasset, New York, Forente stater, 11030
    - North Shore University Hospital
  - Middletown, New York, Forente stater, 10940-4199
    - Tucker Center for Cancer Care at Orange Regional Medical Center
  - Mineola, New York, Forente stater, 11501
    - Winthrop University Hospital
  - New Hyde Park, New York, Forente stater, 11042
    - Long Island Jewish Medical Center
  - New York, New York, Forente stater, 10021
    - New York Weill Cornell Cancer Center at Cornell University
  - Nyack, New York, Forente stater, 10960-1998
    - Union State Bank Cancer Center at Nyack Hospital
  - Plattsburgh, New York, Forente stater, 12901
    - Fitzpatrick Cancer Center at Champlain Valley Physicians Hospital Medical Center
  - Rexford, New York, Forente stater, 12148
    - Riverview Cancer Care Medical Associates, PC
  - Rochester, New York, Forente stater, 14642
    - James P. Wilmot Cancer Center at University of Rochester Medical Center
  - Rochester, New York, Forente stater, 14621
    - Lipson Cancer and Blood Center at Rochester General Hospital
  - Rochester, New York, Forente stater, 14625
    - Genesee Surgical Associates - Linden Oaks Medical Campus
  - Schenectady, New York, Forente stater, 12308
    - New York Oncology Hematology, P.C. - Ellis Office
  - Staten Island, New York, Forente stater, 10305
    - Nalitt Cancer Institute at Staten Island University Hospital
  - Stony Brook, New York, Forente stater, 11794-8174
    - Stony Brook University Cancer Center
  - Syracuse, New York, Forente stater, 13210
    - SUNY Upstate Medical University Hospital
  - Syracuse, New York, Forente stater, 13057
    - CCOP - Hematology-Oncology Associates of Central New York
  - Syracuse, New York, Forente stater, 13203
    - St. Joseph's Hospital Health Center - Syracuse
  - Troy, New York, Forente stater, 12180
    - Samaritan Hospital at Northeast Health
- North Carolina
  - Asheville, North Carolina, Forente stater, 28801
    - Mission Hospitals - Memorial Campus
  - Asheville, North Carolina, Forente stater, 28801
    - Hope A Women's Cancer Center
  - Burlington, North Carolina, Forente stater, 27216
    - Alamance Cancer Center
  - Chapel Hill, North Carolina, Forente stater, 27599-7295
    - Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
  - Charlotte, North Carolina, Forente stater, 28232-2861
    - Blumenthal Cancer Center at Carolinas Medical Center
  - Charlotte, North Carolina, Forente stater, 28233-3549
    - Presbyterian Cancer Center at Presbyterian Hospital
  - Durham, North Carolina, Forente stater, 27710
    - Duke Comprehensive Cancer Center
  - Fayetteville, North Carolina, Forente stater, 28304
    - Cape Fear Valley Medical Center
  - Goldsboro, North Carolina, Forente stater, 27534
    - Wayne Memorial Hospital, Incorporated
  - Greensboro, North Carolina, Forente stater, 27403-1199
    - Moses Cone Regional Cancer Center at Wesley Long Community Hospital
  - Greenville, North Carolina, Forente stater, 27835-6028
    - Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital
  - Hendersonville, North Carolina, Forente stater, 28791
    - Pardee Memorial Hospital
  - High Point, North Carolina, Forente stater, 27261
    - High Point Regional Hospital
  - Kinston, North Carolina, Forente stater, 28501
    - Lenoir Memorial Cancer Center
  - Pinehurst, North Carolina, Forente stater, 28374
    - Moore Regional Community Hospital Comprehensive Cancer Center
  - Wilmington, North Carolina, Forente stater, 28401
    - Zimmer Cancer Center at New Hanover Regional Medical Center
  - Wilson, North Carolina, Forente stater, 27893-3428
    - Wilson Medical Center
  - Winston-Salem, North Carolina, Forente stater, 27157-1096
    - Wake Forest University Comprehensive Cancer Center
  - Winston-Salem, North Carolina, Forente stater, 27103
    - Forsyth Regional Cancer Center at Forsyth Medical Center
- North Dakota
  - Bismarck, North Dakota, Forente stater, 58501
    - Bismarck Cancer Center
  - Bismarck, North Dakota, Forente stater, 58501
    - Cancer Care Center at Medcenter One Hospital
  - Bismarck, North Dakota, Forente stater, 58501
    - Mid Dakota Clinic, P. C.
  - Bismarck, North Dakota, Forente stater, 58502
    - St. Alexius Medical Center
  - Fargo, North Dakota, Forente stater, 58122
    - CCOP - MeritCare Hospital
  - Fargo, North Dakota, Forente stater, 58122
    - MeritCare Medical Group
  - Fargo, North Dakota, Forente stater, 58103
    - Dakota Cancer Institute at Innovis Health - Dakota Clinic
  - Grand Forks, North Dakota, Forente stater, 58201
    - Altru Cancer Center at Altru Hospital
  - Minot, North Dakota, Forente stater, 58701
    - Trinity Cancer Care Center
- Ohio
  - Akron, Ohio, Forente stater, 44307
    - McDowell Cancer Center at Akron General Medical Center
  - Akron, Ohio, Forente stater, 44309-2090
    - Akron City Hospital
  - Canton, Ohio, Forente stater, 44710-1799
    - Aultman Hospital Cancer Center at Aultman Health Foundation
  - Canton, Ohio, Forente stater, 44708
    - Mercy Cancer Center at Mercy Medical Center
  - Chillicothe, Ohio, Forente stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forente stater, 45267
    - Charles M. Barrett Cancer Center at University Hospital
  - Cincinnati, Ohio, Forente stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forente stater, 45220
    - Cancer Treatment Center at Good Samaritan Hospital
  - Cincinnati, Ohio, Forente stater, 45219
    - Christ Hospital Cancer Center
  - Cincinnati, Ohio, Forente stater, 45242
    - Oncology Hematology Care, Incorporated - Blue Ash
  - Cleveland, Ohio, Forente stater, 44195
    - Cleveland Clinic Taussig Cancer Center
  - Cleveland, Ohio, Forente stater, 44109
    - MetroHealth's Cancer Care Center at MetroHealth Medical Center
  - Cleveland, Ohio, Forente stater, 44106
    - Case Comprehensive Cancer Center
  - Cleveland, Ohio, Forente stater, 44111
    - Cleveland Clinic Cancer Center at Fairview Hospital
  - Cleveland, Ohio, Forente stater, 44112
    - Huron Hospital Cancer Care Center
  - Cleveland, Ohio, Forente stater, 44119
    - Euclid Hospital
  - Columbus, Ohio, Forente stater, 43210-1240
    - Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University
  - Columbus, Ohio, Forente stater, 43214-3998
    - Riverside Methodist Hospital Cancer Care
  - Columbus, Ohio, Forente stater, 43215
    - CCOP - Columbus
  - Columbus, Ohio, Forente stater, 43228
    - Doctors Hospital at Ohio Health
  - Columbus, Ohio, Forente stater, 43215
    - Grant Riverside Cancer Services
  - Columbus, Ohio, Forente stater, 43222
    - Mount Carmel West Hospital
  - Dayton, Ohio, Forente stater, 45428
    - Veterans Affairs Medical Center - Dayton
  - Dayton, Ohio, Forente stater, 45405
    - Grandview Hospital
  - Dayton, Ohio, Forente stater, 45406
    - Good Samaritan Hospital
  - Dayton, Ohio, Forente stater, 45415
    - Samaritan North Cancer Care Center
  - Dayton, Ohio, Forente stater, 45429
    - CCOP - Dayton
  - Delaware, Ohio, Forente stater, 43015
    - Grady Memorial Hospital
  - Findlay, Ohio, Forente stater, 45840
    - Blanchard Valley Medical Associates
  - Fremont, Ohio, Forente stater, 43420
    - Fremont Memorial Hospital
  - Independence, Ohio, Forente stater, 44131
    - Community Oncology Group at Cleveland Clinic Cancer Center
  - Kettering, Ohio, Forente stater, 45429
    - Charles F. Kettering Memorial Hospital
  - Lancaster, Ohio, Forente stater, 43130
    - Fairfield Medical Center
  - Lima, Ohio, Forente stater, 45804
    - Lima Memorial Hospital
  - Lima, Ohio, Forente stater, 45801
    - St. Rita's Medical Center
  - Mansfield, Ohio, Forente stater, 44903
    - MedCentral - Mansfield Hospital
  - Marietta, Ohio, Forente stater, 45750
    - Strecker Cancer Center at Marietta Memorial Hospital
  - Maumee, Ohio, Forente stater, 43537
    - St. Luke's Hospital
  - Maumee, Ohio, Forente stater, 43623
    - Northwest Ohio Oncology Center
  - Mayfield Heights, Ohio, Forente stater, 44124
    - Hillcrest Cancer Center at Hillcrest Hospital
  - Middletown, Ohio, Forente stater, 45044
    - Middletown Regional Hospital
  - Newark, Ohio, Forente stater, 43055
    - Licking Memorial Cancer Care Program at Licking Memorial Hospital
  - Oregon, Ohio, Forente stater, 43616
    - St. Charles Mercy Hospital
  - Salem, Ohio, Forente stater, 44460
    - Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford
  - Sandusky, Ohio, Forente stater, 44870
    - Firelands Regional Medical Center
  - Springfield, Ohio, Forente stater, 45505
    - Community Hospital of Springfield and Clark County
  - Springfield, Ohio, Forente stater, 45504
    - Mercy Medical Center
  - Sylvania, Ohio, Forente stater, 43560
    - Promedica Cancer Center at Flower Hospital
  - Tiffin, Ohio, Forente stater, 44883
    - Mercy Hospital of Tiffin
  - Toledo, Ohio, Forente stater, 43608
    - St. Vincent Mercy Medical Center
  - Toledo, Ohio, Forente stater, 43606
    - Toledo Hospital
  - Toledo, Ohio, Forente stater, 43614
    - Medical University of Ohio Cancer Center
  - Toledo, Ohio, Forente stater, 43623
    - Toledo Clinic, Incorporated - Main Clinic
  - Toledo, Ohio, Forente stater, 43623
    - CCOP - Toledo Community Hospital
  - Troy, Ohio, Forente stater, 45373-1300
    - UVMC Cancer Care Center at Upper Valley Medical Center
  - Warren, Ohio, Forente stater, 44484
    - St. Joseph Cancer Center at St. Joseph Health Center
  - Warrensville Heights, Ohio, Forente stater, 44122
    - South Pointe Hospital Cancer Care Center
  - Wauseon, Ohio, Forente stater, 43567
    - Fulton County Health Center
  - Westerville, Ohio, Forente stater, 43081
    - Mount Carmel Cancer Services at Mount Carmel St. Ann's Hospital
  - Wooster, Ohio, Forente stater, 44691
    - Cancer Treatment Center
  - Wooster, Ohio, Forente stater, 44691
    - Cleveland Clinic - Wooster
  - Wright-Patterson Air Force Base, Ohio, Forente stater, 45433-5529
    - United States Air Force Medical Center Wright-Patterson
  - Xenia, Ohio, Forente stater, 45385
    - Ruth G. McMillan Cancer Center at Greene Memorial Hospital
  - Youngstown, Ohio, Forente stater, 44501
    - Tod Children's Hospital - Forum Health
  - Zanesville, Ohio, Forente stater, 43701
    - Genesis - Good Samaritan Hospital
- Oklahoma
  - Lawton, Oklahoma, Forente stater, 73505
    - Comanche County Memorial Hospital
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Mercy Health Center
  - Oklahoma City, Oklahoma, Forente stater, 73112
    - Integris Oncology Services
  - Tulsa, Oklahoma, Forente stater, 74136
    - Natalie Warren Bryant Cancer Center at St. Francis Hospital
  - Tulsa, Oklahoma, Forente stater, 74104
    - LaFortune Cancer Center at St. John Medical Center
- Oregon
  - Bend, Oregon, Forente stater, 97701
    - St. Charles Medical Center - Bend
  - Coos Bay, Oregon, Forente stater, 97420
    - Bay Area Hospital
  - Gresham, Oregon, Forente stater, 97030
    - Legacy Mount Hood Medical Center
  - Milwaukie, Oregon, Forente stater, 97222
    - Providence Milwaukie Hospital
  - Portland, Oregon, Forente stater, 97213-2967
    - Providence Cancer Center at Providence Portland Medical Center
  - Portland, Oregon, Forente stater, 97225
    - CCOP - Columbia River Oncology Program
  - Portland, Oregon, Forente stater, 97225
    - Providence St. Vincent Medical Center
  - Portland, Oregon, Forente stater, 97210
    - Legacy Good Samaritan Hospital & Medical Center Comprehensive Cancer Center
  - Portland, Oregon, Forente stater, 97227
    - Legacy Emanuel Hospital and Health Center & Children's Hospital
  - Portland, Oregon, Forente stater, 97232
    - Kaiser Permanente Health Care - Portland
  - Salem, Oregon, Forente stater, 97309-5014
    - Salem Hospital Regional Cancer Care Services
  - Tualatin, Oregon, Forente stater, 97062
    - Legacy Meridian Park Hospital
- Pennsylvania
  - Abington, Pennsylvania, Forente stater, 19001
    - Rosenfeld Cancer Center at Abington Memorial Hospital
  - Allentown, Pennsylvania, Forente stater, 18102
    - Sacred Heart Hospital
  - Allentown, Pennsylvania, Forente stater, 18105
    - Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
  - Bethlehem, Pennsylvania, Forente stater, 18015
    - St. Luke's Hospital Cancer Center
  - Bryn Mawr, Pennsylvania, Forente stater, 19010
    - Bryn Mawr Hospital
  - Danville, Pennsylvania, Forente stater, 17822-0001
    - Geisinger Medical Center
  - Drexel Hill, Pennsylvania, Forente stater, 19026
    - Delaware County Regional Cancer Center at Delaware County Memorial Hospital
  - DuBois, Pennsylvania, Forente stater, 15801
    - Oncology Hematology Associates of Northern Pennsylvania, P.C. at Hahne Regional Cancer Center
  - East Stroudsburg, Pennsylvania, Forente stater, 18301
    - Dale and Frances Hughes Cancer Center at Pocono Medical Center
  - Easton, Pennsylvania, Forente stater, 18042
    - Easton Regional Cancer Center at Easton Hospital
  - Ephrata, Pennsylvania, Forente stater, 17522
    - Ephrata Cancer Center at Ephrata Community Hospital
  - Erie, Pennsylvania, Forente stater, 16505
    - Regional Cancer Center - Erie
  - Harrisburg, Pennsylvania, Forente stater, 17105
    - PinnacleHealth Regional Cancer Center at Polyclinic Hospital
  - Hershey, Pennsylvania, Forente stater, 17033-0850
    - Penn State Cancer Institute at Milton S. Hershey Medical Center
  - Kittanning, Pennsylvania, Forente stater, 16201
    - Richard G. Laube Cancer Center at Armstrong County Memorial Hospital
  - Langhorne, Pennsylvania, Forente stater, 19047
    - St. Mary Regional Cancer Center
  - Meadville, Pennsylvania, Forente stater, 16335
    - Meadville Medical Center
  - Media, Pennsylvania, Forente stater, 19063
    - Cancer Center at Riddle Memorial Hospital
  - Paoli, Pennsylvania, Forente stater, 19301-1792
    - Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19104-4283
    - Abramson Cancer Center of the University of Pennsylvania
  - Philadelphia, Pennsylvania, Forente stater, 19111-2497
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forente stater, 19141
    - Albert Einstein Cancer Center
  - Philadelphia, Pennsylvania, Forente stater, 19107
    - Joan Karnell Cancer Center at Pennsylvania Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19114
    - Frankford Hospital - Torresdale Campus
  - Philadelphia, Pennsylvania, Forente stater, 19118
    - Chestnut Hill Healthcare Cancer Center
  - Phoenixville, Pennsylvania, Forente stater, 19460
    - Cancer Center at Phoenixville Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15212
    - Allegheny Cancer Center at Allegheny General Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15224-1791
    - Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15232
    - Hillman Cancer Center at University of Pittsburgh Cancer Institute
  - Pittsburgh, Pennsylvania, Forente stater, 15219
    - Mercy Cancer Institute at Mercy Hospital
  - Pottstown, Pennsylvania, Forente stater, 19464
    - Pottstown Memorial Regional Cancer Center
  - Reading, Pennsylvania, Forente stater, 19612-6052
    - Reading Hospital and Medical Center
  - Reading, Pennsylvania, Forente stater, 19604
    - St. Joseph Medical Center
  - Scranton, Pennsylvania, Forente stater, 18501
    - Mercy Hospital Cancer Center - Scranton
  - Scranton, Pennsylvania, Forente stater, 18510
    - Hematology and Oncology Associates
  - Sellersville, Pennsylvania, Forente stater, 18960
    - Grand View Hospital
  - State College, Pennsylvania, Forente stater, 16803
    - Mount Nittany Medical Center
  - Upland, Pennsylvania, Forente stater, 19013
    - Associates in Hematology-Oncology, PC at Crozer Regional Cancer Center
  - West Grove, Pennsylvania, Forente stater, 19390-9499
    - Jennersville Regional Hospital
  - Wilkes-Barre, Pennsylvania, Forente stater, 18711
    - Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
  - Wynnewood, Pennsylvania, Forente stater, 19096
    - CCOP - MainLine Health
  - Wynnewood, Pennsylvania, Forente stater, 19096
    - Lankenau Cancer Center at Lankenau Hospital
  - York, Pennsylvania, Forente stater, 17403
    - York Cancer Center at Wellspan Health
- Rhode Island
  - Pawtucket, Rhode Island, Forente stater, 02860
    - Memorial Hospital of Rhode Island
  - Providence, Rhode Island, Forente stater, 02908
    - Roger Williams Medical Center
  - Providence, Rhode Island, Forente stater, 02903
    - Rhode Island Hospital Comprehensive Cancer Center
  - Providence, Rhode Island, Forente stater, 02906
    - Miriam Hospital at Lifespan
  - Warwick, Rhode Island, Forente stater, 02886
    - Kent County Memorial Hospital
- South Carolina
  - Aiken, South Carolina, Forente stater, 29801
    - Cancer Care Institute of Carolina at Aiken Regional Medical Centers
  - Charleston, South Carolina, Forente stater, 29425
    - Hollings Cancer Center at Medical University of South Carolina
  - Charleston, South Carolina, Forente stater, 29401
    - Roper St. Francis Cancer Center at Roper Hospital
  - Florence, South Carolina, Forente stater, 29501
    - McLeod Regional Medical Center
  - Greenville, South Carolina, Forente stater, 29615
    - CCOP - Greenville
  - Greenville, South Carolina, Forente stater, 29601
    - Bon Secours St. Francis Health System
- South Dakota
  - Rapid City, South Dakota, Forente stater, 57701
    - Rapid City Regional Hospital
  - Sioux Falls, South Dakota, Forente stater, 57105
    - Avera Cancer Institute
  - Sioux Falls, South Dakota, Forente stater, 57117-5039
    - Sioux Valley Hospital and University of South Dakota Medical Center
  - Sioux Falls, South Dakota, Forente stater, 57105
    - Medical X-Ray Center, PC
- Tennessee
  - Chattanooga, Tennessee, Forente stater, 37403
    - Erlanger Cancer Center
  - Kingsport, Tennessee, Forente stater, 37662
    - Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center
  - Knoxville, Tennessee, Forente stater, 37916
    - Thompson Cancer Survival Center
  - Knoxville, Tennessee, Forente stater, 37920-6999
    - U.T. Cancer Institute at University of Tennessee Medical Center
  - Memphis, Tennessee, Forente stater, 38120
    - Baptist Centers for Cancer Care
- Texas
  - Austin, Texas, Forente stater, 78701
    - Seton Shivers Cancer Program at Brackenridge Hospital
  - Bryan, Texas, Forente stater, 77802
    - St. Joseph Regional Cancer Center
  - Dallas, Texas, Forente stater, 75230
    - Medical City Dallas Hospital
  - Dallas, Texas, Forente stater, 75390
    - Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
  - Dallas, Texas, Forente stater, 75246
    - Baylor University Medical Center - Dallas
  - Dallas, Texas, Forente stater, 75231
    - Presbyterian Hospital of Dallas
  - Houston, Texas, Forente stater, 77030
    - Baylor University Medical Center - Houston
  - Houston, Texas, Forente stater, 77030-4009
    - M.D. Anderson Cancer Center at University of Texas
  - Laredo, Texas, Forente stater, 78041
    - Doctor's Hospital of Laredo
  - Lubbock, Texas, Forente stater, 79410-1894
    - Joe Arrington Cancer Research and Treatment Center
  - San Antonio, Texas, Forente stater, 78229-3900
    - University of Texas Health Science Center at San Antonio
  - Temple, Texas, Forente stater, 76508
    - CCOP - Scott and White Hospital
- Utah
  - Logan, Utah, Forente stater, 84321
    - Logan Regional Hospital
  - Murray, Utah, Forente stater, 84107
    - Cottonwood Hospital Medical Center
  - Ogden, Utah, Forente stater, 84403
    - McKay-Dee Hospital Center
  - Provo, Utah, Forente stater, 84604
    - Utah Valley Regional Medical Center - Provo
  - Saint George, Utah, Forente stater, 84770
    - Dixie Regional Medical Center - East Campus
  - Salt Lake City, Utah, Forente stater, 84143
    - LDS Hospital
  - Salt Lake City, Utah, Forente stater, 84112
    - Huntsman Cancer Institute at University of Utah
  - Salt Lake City, Utah, Forente stater, 84106
    - Utah Cancer Specialists at UCS Cancer Center
- Vermont
  - Bennington, Vermont, Forente stater, 05201
    - Green Mountain Oncology Group
  - Bennington, Vermont, Forente stater, 05201
    - Southwestern Vermont Regional Cancer Center
  - Berlin, Vermont, Forente stater, 05602
    - Mountainview Medical
  - Burlington, Vermont, Forente stater, 05401
    - Fletcher Allen Health Care - University Health Center Campus
  - Rutland, Vermont, Forente stater, 05701
    - Community Cancer Center at Rutland Regional Medical Center
  - Windsor, Vermont, Forente stater, 05089
    - Mount Ascutney Hospital
- Virginia
  - Charlottesville, Virginia, Forente stater, 22908
    - University of Virginia Cancer Center
  - Charlottesville, Virginia, Forente stater, 22901
    - Martha Jefferson Hospital Cancer Care Center
  - Danville, Virginia, Forente stater, 24541
    - Danville Regional Medical Center
  - Hampton, Virginia, Forente stater, 23666
    - Virginia Oncology Associates - Hampton
  - Kilmarnock, Virginia, Forente stater, 22482
    - Rappahannock General Hospital
  - Lynchburg, Virginia, Forente stater, 24501
    - Lynchburg Hematology-Oncology Clinic
  - Martinsville, Virginia, Forente stater, 24115
    - Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County
  - Newport News, Virginia, Forente stater, 23601
    - Peninsula Cancer Institute
  - Norfolk, Virginia, Forente stater, 23507
    - Sentara Cancer Institute at Sentara Norfolk General Hospital
  - Portsmouth, Virginia, Forente stater, 23708-2197
    - Naval Medical Center - Portsmouth
  - Richmond, Virginia, Forente stater, 23298-0037
    - Massey Cancer Center at Virginia Commonwealth University
- Washington
  - Auburn, Washington, Forente stater, 98002
    - Auburn Regional Center for Cancer Care
  - Bellevue, Washington, Forente stater, 98004
    - Overlake Cancer Center at Overtake Hospital Medical Center
  - Bellingham, Washington, Forente stater, 98225
    - St. Joseph Hospital Community Cancer Center
  - Centralia, Washington, Forente stater, 98531-9027
    - Providence Centralia Hospital Regional Cancer Center
  - Federal Way, Washington, Forente stater, 98003
    - St. Francis Hospital
  - Kirkland, Washington, Forente stater, 98033
    - Cascade Cancer Center at Evergreen Hospital Medical Center
  - Olympia, Washington, Forente stater, 98507
    - Capital Medical Center
  - Olympia, Washington, Forente stater, 98506-5166
    - Providence St. Peter Hospital Regional Cancer Center
  - Puyallup, Washington, Forente stater, 98372
    - Good Samaritan Cancer Center
  - Renton, Washington, Forente stater, 98055
    - Valley Medical Center
  - Seattle, Washington, Forente stater, 98101
    - CCOP - Virginia Mason Research Center
  - Seattle, Washington, Forente stater, 98104
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forente stater, 98112
    - Group Health Central Hospital
  - Seattle, Washington, Forente stater, 98195-6043
    - University Cancer Center at University of Washington Medical Center
  - Seattle, Washington, Forente stater, 98114
    - Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
  - Tacoma, Washington, Forente stater, 98405
    - Allenmore Hospital
  - Tacoma, Washington, Forente stater, 98405
    - CCOP - Northwest
  - Tacoma, Washington, Forente stater, 98499
    - St. Clare Hospital
  - Tacoma, Washington, Forente stater, 98405-3004
    - St. Joseph Medical Center at Franciscan Health System
  - Vancouver, Washington, Forente stater, 98668
    - Southwest Washington Medical Center Cancer Center
  - Walla Walla, Washington, Forente stater, 99362
    - St. Mary Regional Cancer Center at St. Mary Medical Center
- West Virginia
  - Charleston, West Virginia, Forente stater, 25304
    - West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division
  - Huntington, West Virginia, Forente stater, 25702
    - St. Mary's Regional Cancer Center at St. Mary's Medical Center
  - Huntington, West Virginia, Forente stater, 25701
    - Marshall University Medical Center
  - Morgantown, West Virginia, Forente stater, 26506
    - Mary Babb Randolph Cancer Center at West Virginia University Hospitals
  - Wheeling, West Virginia, Forente stater, 26003
    - Schiffler Cancer Center at Wheeling Hospital
- Wisconsin
  - Appleton, Wisconsin, Forente stater, 54911
    - Theda Care Cancer Institute
  - Appleton, Wisconsin, Forente stater, 54911
    - Fox Valley Surgical Associates at Appleton Medical Center
  - Fond Du Lac, Wisconsin, Forente stater, 54935
    - Central Wisconsin Cancer Program at Agnesian HealthCare
  - Glendale, Wisconsin, Forente stater, 53212-1038
    - Oncology Alliance, SC - Milwaukee - East
  - Green Bay, Wisconsin, Forente stater, 54307-3508
    - St. Vincent Hospital Regional Cancer Center
  - Green Bay, Wisconsin, Forente stater, 54303
    - Green Bay Oncology, Limited at St. Mary's Hospital
  - Green Bay, Wisconsin, Forente stater, 54303
    - St. Mary's Hospital Medical Center - Green Bay
  - Green Bay, Wisconsin, Forente stater, 54301-3526
    - Green Bay Oncology, Limited at St. Vincent Hospital
  - Green Bay, Wisconsin, Forente stater, 54311
    - Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
  - Janesville, Wisconsin, Forente stater, 53547
    - Mercy Regional Cancer Center
  - La Crosse, Wisconsin, Forente stater, 54601
    - Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center
  - La Crosse, Wisconsin, Forente stater, 54601
    - Franciscan Skemp Healthcare
  - Madison, Wisconsin, Forente stater, 53792-6164
    - University of Wisconsin Comprehensive Cancer Center
  - Madison, Wisconsin, Forente stater, 53715
    - Dean Medical Center - Fish Hatchery
  - Marinette, Wisconsin, Forente stater, 54143
    - Bay Area Cancer Care Center at Bay Area Medical Center
  - Marshfield, Wisconsin, Forente stater, 54449
    - Marshfield Clinic - Marshfield Center
  - Menomonee Falls, Wisconsin, Forente stater, 53051
    - Community Memorial Hospital Cancer Care Center
  - Milwaukee, Wisconsin, Forente stater, 53226
    - Medical College of Wisconsin Cancer Center
  - Milwaukee, Wisconsin, Forente stater, 53210
    - St. Joseph Regional Medical Center
  - Oconto Falls, Wisconsin, Forente stater, 54154
    - Green Bay Oncology, Limited - Oconto Falls
  - Racine, Wisconsin, Forente stater, 53405
    - All Saints Cancer Center at All Saints Medical Center
  - Rhinelander, Wisconsin, Forente stater, 54501
    - Ministry Medical Group at Saint Mary's Hospital
  - Sturgeon Bay, Wisconsin, Forente stater, 54235
    - Green Bay Oncology, Limited - Sturgeon Bay
  - Waukesha, Wisconsin, Forente stater, 53188
    - Waukesha Memorial Hospital Regional Cancer Center
  - Wausau, Wisconsin, Forente stater, 54401
    - University of Wisconsin Cancer Center at Aspirus Wausau Hospital
Puerto Rico
- - Ponce, Puerto Rico, 00733
    - Andres Grillasca Hospital
  - San Juan, Puerto Rico, 00928
    - San Juan City Hospital
  - San Juan, Puerto Rico, 00917
    - Hato Rey Hematology/Oncology Group

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Barn
Voksen
Eldre voksen

Tar imot friske frivillige

Nei

Kjønn som er kvalifisert for studier

Hunn

Beskrivelse

SYKDOMENS KARAKTERISTIKA:

Histologisk bekreftet duktalt karsinom in situ (DCIS) i brystet
- Blandet DCIS og lobulært karsinom in situ (LCIS) tillatt
Må ha gjennomgått lumpektomi
- Marginene må være histologisk fri for sykdom
- Reeksisjon for å oppnå tumorfrie marginer tillatt
- Ikke mer enn 84 dager siden forrige lumpektomi eller re-eksisjon
Mer enn 1 område med DCIS tillatt forutsatt at all sykdom fjernes med svulstfrie marginer
- Masser eller klynger av forkalkning som er klinisk eller mammografisk mistenkelige må biopsieres
Ingen tidligere invasiv brystkreft eller DCIS
- Pasienter med en historie med LCIS er kvalifisert
Ingen tidligere eller samtidig invasiv (inkludert mikroinvasiv) brystkreft
- DCIS "mistenkelig" for mikroinvasjon tillatt
Ingen bilateral malignitet
- Ingen masse eller mammografisk abnormitet som er mistenkelig for malignitet i det motsatte brystet med mindre det ikke er ondartet som påvist ved biopsi
Ingen Pagets sykdom i brystvorten
Ingen positive ipsilaterale aksillære eller intramammære noder
- Ingen palpable noder i den ipsilaterale eller kontralaterale aksillen eller palpable supraclavicular eller infraclavicular noder med mindre de ikke er involvert med tumor som påvist ved biopsi
Hormonreseptorstatus:
- Østrogen- eller progesteronreseptorpositiv som bestemt ved immunhistokjemi
  - Borderline-resultater anses som positive

PASIENT EGENSKAPER:

Alder

Se menopausal status

Kjønn:

Hunn

Menopausal status:

Postmenopausal som definert av minst 1 av følgende:
- Tidligere dokumentert bilateral ooforektomi
- Minst 12 måneder uten spontan blødning
- Alder 55 eller over med tidligere hysterektomi uten ooforektomi
- Alder 54 eller yngre med tidligere hysterektomi uten ooforektomi med dokumentert follikkelstimulerende hormonnivå i postmenopausalt område

Ytelsesstatus

Zubrod 0-2

Forventet levealder

Minst 10 år (unntatt diagnose av brystkreft)

Hematopoetisk

WBC normalt

Hepatisk

AST normal
Bilirubin normalt
Alkalisk fosfatase normal
Ingen leversykdom som vil utelukke administrering av studiemedisiner

Nyre

Kreatinin normalt
Ingen nyresykdom som vil utelukke administrering av studiemedisiner

Kardiovaskulær

Ingen tidligere dokumentert cerebral vaskulær ulykke eller forbigående iskemisk angrep
Ingen tidligere dyp venetrombose
Ingen kardiovaskulær sykdom som vil utelukke administrering av studiemedisiner
Ingen ukontrollert hypertensjon (dvs. systolisk blodtrykk minst 180 mm Hg eller diastolisk blodtrykk minst 110 mm Hg basert på gjennomsnittet av 2 eller flere målinger ved hvert av 2 eller flere besøk etter første screening)
Ingen ukontrollert atrieflimmer

Pulmonal

Ingen lungeemboli

Annen

Ikke gravid eller ammende
Pasienter med en historie med ikke-brystmaligniteter er kvalifisert forutsatt at de har vært sykdomsfrie i ≥ 5 år og av legen anses å ha lav risiko for tilbakefall
Ingen annen malignitet i løpet av de siste 5 årene bortsett fra behandlet basalcelle- eller plateepitelhudkreft, karsinom in situ i livmorhalsen, karsinom in situ i tykktarmen eller melanom in situ
Ingen psykiatriske eller vanedannende lidelser som vil utelukke informert samtykke
Ingen ukontrollert diabetes, definert som hemoglobin A1C større enn 9 % (fastende glukose 200 mg/dL)
Ingen ikke-malign systemisk sykdom som vil utelukke administrering av studiemedisiner

FØR SAMTIDIG TERAPI:

Endokrin terapi

Ingen tidligere eller samtidige aromatasehemmere (f.eks. exemestan eller letrozol) eller tamoxifen
Ingen samtidige raloksifen eller andre selektive østrogenreseptormodulatorer
Ingen samtidig kjønnshormonbehandling (f.eks. østrogen- eller progesteronerstatningsterapi, orale prevensjonsmidler, androgener, analoger med luteiniserende hormonfrigjørende hormon, prolaktinhemmere eller antiandrogener)
- Lavdose østrogen vaginale kremer eller Estring tillatt

Strålebehandling

Strålebehandling for denne kreften igangsatt før studien tillates

Kirurgi

Se Sykdomskarakteristikker
Ingen tidligere eller samtidig mastektomi for DCIS
Tidligere sentinel node biopsi eller aksillær node disseksjon tillatt forutsatt at noder er patologisk negative

Annen

Ingen samtidig warfarin
Ingen annen systemisk terapi for denne kreften startet før studien
Ingen annen samtidig kreftbehandling med mindre det er tillatt av protokolletterforskeren
Ingen samtidig deltakelse i en annen klinisk studie av terapi for DCIS
- Samtidig deltakelse i protokoll NSABP-B-39 tillatt

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Primært formål: Behandling
Tildeling: Randomisert
Intervensjonsmodell: Parallell tildeling
Masking: Firemannsrom

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm	Intervensjon / Behandling
Aktiv komparator: Gruppe 1 tamoxifen 20 mg/dag og en anastrozol-liknende placebo i 5 år	Legemiddel: tamoxifen sitrat 20 mg/dag og placebo i 5 år Stråling: Strålebehandling Adjuvant strålebehandling
Eksperimentell: Gruppe 2 anastrozol, 1 mg/dag og en tamoxifen-liknende placebo i 5 år	Stråling: Strålebehandling Adjuvant strålebehandling Legemiddel: anastrozol 1 mg/dag og placebo i 5 år

Hva måler studien?

Primære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Prosentandel pasienter fri for brystkreft Tidsramme: 10 år	Prosentandel av pasienter fri fra brystkrefthendelse ved 10 år der hendelser inkluderer lokalt, regionalt eller fjernt tilbakefall eller kontralateral brystkreft, invasiv eller DCIS.	10 år

Sekundære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Prosentandel av pasienter fri fra invasiv brystkreft Tidsramme: 10 år	Prosentandel av pasienter fri fra en invasiv brystkrefthendelse der hendelser inkluderer invasiv lokal, regional eller fjern tilbakefall, eller kontralateral brystkreft, som oppstår som en første krefthendelse. Merk at dette endepunktet bare inkluderer invasive brystkreftformer og det primære endepunktet inkluderer både invasive og DCIS brystkreftformer.	10 år
Prosentandel av pasienter fri fra Ipsilateralt tilbakefall Tidsramme: 10 år	Prosentandel av pasienter som er fri for tilbakefall av brystkreft i det ipsilaterale brystet (invasivt og DCIS), som oppstår som en første krefthendelse.	10 år
Prosentandel av pasienter fri fra kontralateral brystkreft Tidsramme: 10 år	Prosentandel av pasienter fri for tilbakefall av brystkreft i det kontralaterale brystet (invasiv og DCIS), som oppstår som en første krefthendelse.	10 år
Prosentandel av pasienter fri for ikke-bryst sekundær kreft Tidsramme: 10 år	Prosentandel av pasienter som er fri for annen primærkreft som ikke er brystkreft bortsett fra plateepitel- eller basalcellekarsinom i huden, karsinom in situ i tykktarmen, melanom in situ eller karsinom in situ i livmorhalsen, som oppstår som en første krefthendelse.	10 år
Prosentandel av pasienter fri fra osteoporotiske brudd Tidsramme: 10 år	Prosentandel av pasienter fri for brudd i hofte, ryggrad og håndledd.	10 år
Prosentandel av pasienter i live og sykdomsfri Tidsramme: 10 år	Prosentandel av pasienter som er fri fra en sykdomsfri overlevelseshendelse der hendelser inkluderer ethvert tilbakefall, sekundær primær kreft og død uansett årsak. Lobulært karsinom in situ (LCIS), basalcelle- eller plateepitelkarsinom i huden, karsinom in situ i tykktarmen, melanom in situ og cervical carcinoma in situ vil ikke inkluderes som residiv eller andre primære kreft.	10 år
Prosentandel av pasienter i live (total overlevelse) Tidsramme: 10 år	Andel pasienter i live.	10 år
Livskvalitet-kort skjema 12 (SF-12) Score for fysisk helsekomponent Tidsramme: 5 år	Det primære resultatet av QOL-delstudien var Medical Outcomes Study-Short Form 12 (SF-12) fysisk helsekomponent-skalapoengsum. SF-12 fysiske poengsum ble beregnet til å ha et område på 0-100 og ble normalisert til å ha et gjennomsnitt på 50 og et standardavvik på 10 i den generelle befolkningen. Høyere score indikerer bedre helse.	5 år
Kvalitetsjustert overlevelsestid Tidsramme: 10 år	Gjennomsnittlig kvalitetsjustert overlevelsestid (i måneder) i hver behandlingsgruppe, estimert ved kvalitetsjustert tid uten symptomer og toksisitet (Q-TWIST).	10 år

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

NSABP Foundation Inc

Samarbeidspartnere

National Cancer Institute (NCI)

Southwest Oncology Group

North Central Cancer Treatment Group

American College of Surgeons

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart

1. januar 2003

Primær fullføring (Faktiske)

1. mars 2015

Studiet fullført (Faktiske)

1. mai 2016

Datoer for studieregistrering

Først innsendt

5. februar 2003

Først innsendt som oppfylte QC-kriteriene

5. februar 2003

Først lagt ut (Anslag)

6. februar 2003

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

20. september 2018

Siste oppdatering sendt inn som oppfylte QC-kriteriene

19. september 2018

Sist bekreftet

1. september 2018

Mer informasjon

Begreper knyttet til denne studien

Nøkkelord

Andre studie-ID-numre

NSABP B-35
NSABP-B-35
SWOG-NSABP-B-35
NCCTG-NSABP-B-35
ACOSOG-NSABP-B-35

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

Kliniske studier på Brystkreft

Tianjin Medical University Cancer Institute and...
Guangxi Medical University; Sun Yat-sen University; Chinese PLA General Hospital og andre samarbeidspartnere

Fullført

Den tekniske operasjonen og standard klinisk anvendelsesprotokoll for CBBCT i diagnostisk prosess for brystkreft (CBBCT)

The Clinical Application Guide of Conebeam Breast CT

Kina
Novartis Pharmaceuticals

Fullført

En fase Ib/II-studie av BEZ235 og Trastuzumab hos pasienter med HER2-positiv brystkreft som mislyktes før Trastuzumab

Metastatisk brystkreft (MBC) | Locally Advance Breast Cancer (LABC)

Storbritannia, Spania
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Ukjent

En studie av TQ-B3525-tabletter kombinert med Fulvestrant-injeksjon hos personer med HR-positive, HER2-negative og PIK3CA-mutasjonsavansert brystkreft

HR-positiv, HER2-negativ og PIK3CA Mutation Advanced Breast Cancer

Kina
Emory University
National Cancer Institute (NCI)

Tilbaketrukket

Stereotaktisk radiokirurgi med Abemaciclib, Ribociclib eller Palbociclib ved behandling av pasienter med hormonreseptorpositiv brystkreft med hjernemetastaser

Prognostisk stadium IV brystkreft AJCC v8 | Metastatisk malign neoplasma i hjernen | Metastatisk brystkarsinom | Anatomic Stage IV Breast Cancer American Joint Committee on Cancer (AJCC) v8
NRG Oncology
National Cancer Institute (NCI)

Aktiv, ikke rekrutterende

Tester om behandling av brystkreftmetastaser med kirurgi eller høydosestråling forbedrer overlevelsen

Anatomisk stadium IV brystkreft AJCC v8 | Prognostisk stadium IV brystkreft AJCC v8 | Metastatisk malign neoplasma i beinet | Metastatisk malign neoplasma i lymfeknutene | Metastatisk malign neoplasma i leveren | Metastatisk brystkarsinom | Metastatisk malign neoplasma i lungen | Metastatisk malign neoplasma... og andre forhold

Forente stater, Canada, Saudi-Arabia, Korea, Republikken

Kliniske studier på tamoxifen sitrat

Avecho Biotechnology

Har ikke rekruttert ennå

Evaluering av effektiviteten og sikkerheten til CBD TPM-kapsler for bruk ved søvnløshet

Søvnløshet
Ziekenhuis Oost-Limburg

Fullført

Magnesiumbalanse av sitratbasert kontinuerlig venovenøs hemofiltrering, effekt av sitratdose.

Akutt nyreskade | Kritisk syk

Belgia
Jean-Philippe Bertocchio

Fullført

Alkalisering av urologer og nefrologer (AlcalUN)

Nefrolitiasis | Kroppsvekt | Blodtrykk | Metabolsk acidose | Ekstracellulær endring

Frankrike
University of California, San Diego

Rekruttering

Cannabidiol for å redusere angstreaktivitet: En randomisert kontrollert prøvelse i sosial angstlidelse

Sosial angst | Sosial angst

Forente stater
University Hospital, Bordeaux

Rekruttering

68Ga-citrat PET/CT for diagnostisering av kronisk hofte- eller kneprotese (Gal-I-TEP)

Prostetisk leddinfeksjon

Frankrike
Susan Chang
American Brain Tumor Association

Avsluttet

68Ga-citrat PET/MR-bildebehandling for gliom

Glioma

Forente stater
University Hospital, Bordeaux

Har ikke rekruttert ennå

Bidrag av PET/CT med Gallium 68 Citrate (68Ga-PET/CT) for diagnostisering av proteseklaffinfektiv endokarditt (CiGal-EI-TEP)

Infektiv endokarditt

Frankrike
Eli Lilly and Company

Fullført

A Study to Compare LY2963016 and US-approved Lantus® After Single Dose Administration to Healthy Participants

Sunn

Singapore
NYU Langone Health
National Institutes of Health (NIH); Tilray

Fullført

Effekter av Cannabidiol i alkoholbruksforstyrrelser

Alkoholbruksforstyrrelse

Forente stater
Medical University of Gdansk

Fullført

HEmoFiltrering med sitronsyre antikoagulasjon (HEFCAA)

Akutt nyreskade | Nyreerstatningsterapi | Akutt nyresvikt | Hemofiltrering

Polen

Anastrozol eller Tamoxifen i behandling av postmenopausale kvinner med duktalt karsinom in situ som gjennomgår lumpektomi og strålebehandling

En klinisk studie som sammenligner anastrozol med tamoksifen hos postmenopausale pasienter med ductal carcinoma in situ (DCIS) som gjennomgår lumpektomi med strålebehandling

Studieoversikt

Status

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

Studietype

Registrering (Faktiske)

Fase

Kontakter og plasseringer

Studiesteder

Deltakelseskriterier

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Tar imot friske frivillige

Kjønn som er kvalifisert for studier

Beskrivelse

Studieplan

Hvordan er studiet utformet?

Designdetaljer

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm

Intervensjon / Behandling

Hva måler studien?

Primære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Samarbeidspartnere og etterforskere

Sponsor

Samarbeidspartnere

Publikasjoner og nyttige lenker

Generelle publikasjoner

Studierekorddatoer

Studer hoveddatoer

Studiestart

Primær fullføring (Faktiske)

Studiet fullført (Faktiske)

Datoer for studieregistrering

Først innsendt

Først innsendt som oppfylte QC-kriteriene

Først lagt ut (Anslag)

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

Siste oppdatering sendt inn som oppfylte QC-kriteriene

Sist bekreftet

Mer informasjon

Begreper knyttet til denne studien

Nøkkelord

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

Kliniske studier på Brystkreft

Kliniske studier på tamoxifen sitrat

Søk i lignende forsøk

Sponsorer og samarbeidspartnere

Medisinsk tilstand

Legemiddelintervensjoner

CROs by country

CROs in India

Forhold

Sjeldne sykdommer

Legemiddelintervensjoner

Kosttilskudd

Sponsor / samarbeidspartnere

Steder