Denne siden ble automatisk oversatt og nøyaktigheten av oversettelsen er ikke garantert. Vennligst referer til engelsk versjon for en kildetekst.

Tipranavir in Patients With Progressive, Systemic HIV-1 Disease Who Have Failed or Are Intolerant to Currently Approved Treatments for HIV Infection

29. november 2016 oppdatert av: Boehringer Ingelheim

An Open Label Safety Study to Evaluate the Safety of Tipranavir Plus Ritonavir When Used in Combination With Other Agents for the Treatment of Patients With HIV Infection Who Have Failed and/or Are Intolerant to Combination Antiretroviral Therapy and Have Limited Treatment Options

To provide early access to tipranavir and evaluate the safety and tolerance of tipranavir combined with low dose of ritonavir in patients with progressive, HIV-1 disease who have failed or are intolerant to currently approved treatments for HIV infection, who are unable to participate in another tipranavir controlled clinical trial and have an urgent need for anti-HIV treatment.

Studieoversikt

Status

Godkjent for markedsføring

Forhold

Intervensjon / Behandling

Studietype

Utvidet tilgang

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

  • Australia
    • New South Wales
      • Camperdown, New South Wales, Australia
        • 1182.58.61005 Royal Prince Alfred Hospital
      • Darlinghurst, New South Wales, Australia
        • 1182.58.61008 St Vincents Hospital
      • Darlinghurst, New South Wales, Australia
        • 1182.58.61011 St Vincents Hospital
      • Darlinghurst, New South Wales, Australia
        • 1182.58.61014 St Vincents Hospital
      • Darlinghusrst, New South Wales, Australia
        • 1182.58.61007 407 Doctors Pty Ltd
      • Darlinghusrst, New South Wales, Australia
        • 1182.58.61019 407 Bouke Street
      • Kingswood, New South Wales, Australia
        • 1182.58.61022 Sexual Health Clinic
      • Liverpool, New South Wales, Australia
        • 1182.58.61012 Bigge Park Centre
      • Randwick, New South Wales, Australia
        • 1182.58.61003 The Prince of Wales Hospital
      • St Leonards, New South Wales, Australia
        • 1182.58.61002 Royal North Shore Hospital
      • Surry Hills, New South Wales, Australia
        • 1182.58.61006 Albion Street Clinic
      • Westmead, New South Wales, Australia
        • 1182.58.61025 Immunology Department
    • Queensland
      • Brisbane, Queensland, Australia
        • 1182.58.61010 Biala Building
      • Herston, Queensland, Australia
        • 1182.58.61009 Level 6
      • Nambour, Queensland, Australia
        • 1182.58.61024
      • Woolloongabba, Queensland, Australia
        • 1182.58.61016 Princess Alexandra Hospital
    • South Australia
      • Adelaide, South Australia, Australia
        • 1182.58.61020
      • Bedford Park, South Australia, Australia
        • 1182.58.61015 Flinders Medical Centre
    • Victoria
      • Carlton, Victoria, Australia
        • 1182.58.61001 88 Rathdowne Street Carlton
      • Carlton, Victoria, Australia
        • 1182.58.61018 Melbourne Sexual Health Clinic
      • Clayton, Victoria, Australia
        • 1182.58.61017 Department of Infectious Diseases
      • Melbourne, Victoria, Australia
        • 1182.58.61013 Melbourne Sexual Health Clinic
      • Melbourne, Victoria, Australia
        • 1182.58.61023
      • South Yarra, Victoria, Australia
        • 1182.58.61021
    • Western Australia
      • Perth, Western Australia, Australia
        • 1182.58.61004 Royal Perth Hospital
  • Belgia
      • Antwerpen, Belgia
        • 1182.58.3201 Boehringer Ingelheim Investigational Site
      • Bruxelles, Belgia
        • 1182.58.3202 Boehringer Ingelheim Investigational Site
      • Bruxelles, Belgia
        • 1182.58.3203 Boehringer Ingelheim Investigational Site
      • Liège, Belgia
        • 1182.58.3204 Boehringer Ingelheim Investigational Site
  • Danmark
      • Aarhus C, Danmark
        • 1182.58.4505 Aarhus Universitetshospital Skejby
      • København Ø, Danmark
        • 1182.58.4501 Rigshospitalet
      • Odense C, Danmark
        • 1182.58.4504 Odense Universitetshospital
  • Forente stater
    • Arizona
      • Scottsdale, Arizona, Forente stater
        • 1182.58.31
    • California
      • Los Angeles, California, Forente stater
        • 1182.58.29
      • Los Angeles, California, Forente stater
        • 1182.58.34 Campus Code 696446
      • Los Angeles, California, Forente stater
        • 1182.58.42 Synergy Hematology/Oncology
      • Los Angeles, California, Forente stater
        • 1182.58.43
      • San Francisco, California, Forente stater
        • 1182.58.03
      • San Francisco, California, Forente stater
        • 1182.58.33 Kaiser Permanente Medical Center, Clinical Trials Unit
    • Connecticut
      • Los Angeles, Connecticut, Forente stater
        • 1182.58.37 AIDS Health Care Foundation
      • Norwalk, Connecticut, Forente stater
        • 1182.58.41 Circle Medical, LLC
    • District of Columbia
      • Washington, District of Columbia, Forente stater
        • 1182.58.28
    • Florida
      • Miami Beach, Florida, Forente stater
        • 1182.58.38
      • South Miami, Florida, Forente stater
        • 1182.58.40 Drs. Raben and Feldman Research Associates
      • Tampa, Florida, Forente stater
        • 1182.58.23 Hillsborough County Health Department
    • Georgia
      • Atlanta, Georgia, Forente stater
        • 1182.58.36 Suite 525
    • Hawaii
      • Honolulu, Hawaii, Forente stater
        • 1182.58.08
    • Illinois
      • Chicago, Illinois, Forente stater
        • 1182.58.22
    • Louisiana
      • New Orleans, Louisiana, Forente stater
        • 1182.58.32
    • Massachusetts
      • Boston, Massachusetts, Forente stater
        • 1182.58.15
    • Michigan
      • Detroit, Michigan, Forente stater
        • 1182.58.19 Henry Ford Hospital
    • Missouri
      • Kansas City, Missouri, Forente stater
        • 1182.58.04 Kansas City Free Health Clinic
      • St. Louis, Missouri, Forente stater
        • 1182.58.25 Wohl Clinic
    • Nevada
      • Las Vegas, Nevada, Forente stater
        • 1182.58.02 Wellness Center
    • New York
      • New York, New York, Forente stater
        • 1182.58.09 Polari Medical Group
    • North Carolina
      • Chapel Hill, North Carolina, Forente stater
        • 1182.58.30
    • Ohio
      • Cincinnati, Ohio, Forente stater
        • 1182.58.06 University of Cincinnati Medical Center, Infectious diseases
    • Oregon
      • Portland, Oregon, Forente stater
        • 1182.58.35
    • Pennsylvania
      • Philadelphia, Pennsylvania, Forente stater
        • 1182.58.14
      • Pittsburgh, Pennsylvania, Forente stater
        • 1182.58.20 University of Pittsburgh
    • South Carolina
      • Columbia, South Carolina, Forente stater
        • 1182.58.01 Boehringer Ingelheim Investigational Site
    • Tennessee
      • Nashville, Tennessee, Forente stater
        • 1182.58.10 Comprehensive Care Center
    • Texas
      • Dallas, Texas, Forente stater
        • 1182.58.18 University of Texas Southwest Medical Center at Dallas
      • Houston, Texas, Forente stater
        • 1182.58.07
      • San Antonio, Texas, Forente stater
        • 1182.58.039 Olmos Park Medical Associates
    • Washington
      • Seattle, Washington, Forente stater
        • 1182.58.11 Swedish Medical Center
    • Wisconsin
      • Madison, Wisconsin, Forente stater
        • 1182.58.44 VW Hospital and Clinics
  • Frankrike
      • Aix en Provence cedex 1, Frankrike
        • 1182.58.33029 Hôpital Aix
      • Besançon cedex, Frankrike
        • 1182.58.33001 Hôpital Saint Jacques
      • Bobigny cedex, Frankrike
        • 1182.58.33022 Hôpital Avicenne
      • Clamart cedex, Frankrike
        • 1182.58.33020 Hôpital Antoine Beclère
      • Colombes, Frankrike
        • 1182.58.33028 Hôpital Louis Mourier
      • Dijon cedex, Frankrike
        • 1182.58.33027 Hôpital
      • Garches, Frankrike
        • 1182.58.33034 Hôpital Raymond Poincarré
      • Le Kremlin Bicêtre cedex, Frankrike
        • 1182.58.33006 Hôpital Bicêtre
      • Lyon cedex 2, Frankrike
        • 1182.58.33019 Hôpital de l'Hôtel Dieu
      • Lyon cedex 3, Frankrike
        • 1182.58.33031 Hôpital edouard Herriot
      • Marseille cedex 5, Frankrike
        • 1182.58.33009 Hôpital de la Conception
      • Marseille cedex 9, Frankrike
        • 1182.58.33023 Hôpital Sainte Marguerite
      • Montpellier, Frankrike
        • 1182.58.33030 Hôpital Saint Eloi
      • Mulhouse cedex 1, Frankrike
        • 1182.58.33032 Hôpital Emile Muller
      • Nantes cedex 1, Frankrike
        • 1182.58.33008 Hôpital Hôtel Dieu
      • Nice cedex 3, Frankrike
        • 1182.58.33003 Hôpital de l'Archet
      • Paris, Frankrike
        • 1182.58.33018 Hôpital Saint Antoine
      • Paris, Frankrike
        • 1182.58.33024 Hôpital Necker
      • Paris cedex 10, Frankrike
        • 1182.58.33013 Hôpital Saint Louis
      • Paris cedex 14, Frankrike
        • 1182.58.33014 Hôpital Cochin
      • Paris cedex 15, Frankrike
        • 1182.58.33007 Hôpital Georges Pompidou
      • Paris cedex 18, Frankrike
        • 1182.58.33005 Hôpital Bichat
      • Paris cedex 18, Frankrike
        • 1182.58.33017 Hôpital Bichat Claude Bernard
      • Paris cedex 20, Frankrike
        • 1182.58.33033 Hôpital Tenon
      • Pointe A Pitre, Frankrike
        • 1182.58.33035 Hôpital des Abîmes
      • Reims cedex, Frankrike
        • 1182.58.33012 Hôpital Robert Debré
      • Rennes cedex 9, Frankrike
        • 1182.58.33026 Hôpital Ponchaillou
      • Strasbourg cedex, Frankrike
        • 1182.58.33015 Hôpital Civil
      • Suresnes cedex, Frankrike
        • 1182.58.33025 Hôpital Foch
      • Toulon cedex, Frankrike
        • 1182.58.33021 Hôpital Chalucet
      • Toulouse cedex 9, Frankrike
        • 1182.58.33002 Hôpital Purpan
      • Tourcoing, Frankrike
        • 1182.58.33016
      • Vandoeuvre Les Nancy, Frankrike
        • 1182.58.33010 Hôpital Brabois
      • Villejuif cedex, Frankrike
        • 1182.58.33011 Hôpital Paul Brousse
  • Hellas
      • Athens, Hellas
        • 1182.58.3001
  • Irland
      • Dublin, Irland
        • 1182.58.44016 St James Hospital, Dept of Genito Urinary Medicine
      • Dublin 12, Irland
        • 1182.58.44029 Our Lady For Sick Children
  • Italia
      • Brescia, Italia
        • 1182.58.3903 Università di Brescia
      • Foggia, Italia
        • 1182.58.3904 Ospedali Riuniti di Foggia
      • Milano, Italia
        • 1182.58.3901 Ospedale Luigi Sacco
      • Milano, Italia
        • 1182.58.3902 Ospedale L. Sacco
      • Rimini, Italia
        • 1182.58.3907 Presidio Ospedaliero di Rimini
      • S. Angelo Lodigiano (lo), Italia
        • 1182.58.3905 Presidio Dalmati
      • Torino, Italia
        • 1182.58.3906 Ospedale Infantile Regina Margherita
      • Verona, Italia
        • 1182.58.3908 Centro Medicina Preventiva
  • Portugal
      • Cascais, Portugal
        • 1182.58.35102 Hospital Condes Castro Guimarães
  • Storbritannia
      • Beckenham, Storbritannia
        • 1182.58.44020 Beckenham Hospital
      • Brighton, Storbritannia
        • 1182.58.44004 Boehringer Ingelheim Investigational Site
      • Cardiff, Storbritannia
        • 1182.58.44002 Boehringer Ingelheim Investigational Site
      • Chertsey, Storbritannia
        • 1182.58.44025 Boehringer Ingelheim Investigational Site
      • Chichester, Storbritannia
        • 1182.58.44019 Boehringer Ingelheim Investigational Site
      • Edinburgh, Storbritannia
        • 1182.58.44009 Boehringer Ingelheim Investigational Site
      • Harrow, Storbritannia
        • 1182.58.44023 Boehringer Ingelheim Investigational Site
      • Leeds, Storbritannia
        • 1182.58.44024 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44003 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44005 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44008 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44010 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44014 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44017 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44018 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44026 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44027 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44028 Boehringer Ingelheim Investigational Site
      • London, Storbritannia
        • 1182.58.44031 Boehringer Ingelheim Investigational Site
      • Peterborough, Storbritannia
        • 1182.58.44011 Boehringer Ingelheim Investigational Site
      • Woolwich, Storbritannia
        • 1182.58.44022 Boehringer Ingelheim Investigational Site
      • Woolwich, Storbritannia
        • 1182.58.44030 Boehringer Ingelheim Investigational Site
  • Sveits
      • Basel, Sveits
        • 1182.58.4101 Boehringer Ingelheim Investigational Site
      • Bern, Sveits
        • 1182.58.4103 Boehringer Ingelheim Investigational Site
      • Genève, Sveits
        • 1182.58.4104 Boehringer Ingelheim Investigational Site
      • Genève, Sveits
        • 1182.58.4107 Boehringer Ingelheim Investigational Site
      • Zürich, Sveits
        • 1182.58.4102 Boehringer Ingelheim Investigational Site
      • Zürich, Sveits
        • 1182.58.4105 Boehringer Ingelheim Investigational Site
  • Sør-Afrika
      • Cape Town, Sør-Afrika
        • 1182.58.27095 Boehringer Ingelheim Investigational Site
      • Cape Town, Sør-Afrika
        • 1182.58.27098 Boehringer Ingelheim Investigational Site
      • Cape Town, Sør-Afrika
        • 1182.58.27099 Boehringer Ingelheim Investigational Site
      • Durban, Sør-Afrika
        • 1182.58.27096 Boehringer Ingelheim Investigational Site
      • Westville, Durban, Sør-Afrika
        • 1182.58.27097 Boehringer Ingelheim Investigational Site

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

2 år og eldre (Barn, Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Kjønn som er kvalifisert for studier

Alle

Beskrivelse

Inclusion criteria:

Patients aho have a positive serology HIV antibody test confirmed by Western blot, p24 antigen assay, HIV-1 RNA or HIV culture and are highly pre-treated and virus resistant to multiple protease inhibitors.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Boehringer Ingelheim

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart

1. mai 2003

Primær fullføring (Faktiske)

1. april 2014

Studiet fullført (Faktiske)

1. april 2014

Datoer for studieregistrering

Først innsendt

10. juni 2003

Først innsendt som oppfylte QC-kriteriene

11. juni 2003

Først lagt ut (Anslag)

12. juni 2003

Oppdateringer av studieposter

Sist oppdatering lagt ut (Anslag)

30. november 2016

Siste oppdatering sendt inn som oppfylte QC-kriteriene

29. november 2016

Sist bekreftet

1. juli 2014

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

  • 1182.58

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

Abonnere