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Tamoxifen Citrate, Letrozol, Anastrozol eller Exemestane med eller uten kjemoterapi ved behandling av pasienter med invasiv RxPONDER brystkreft

23. april 2024 oppdatert av: National Cancer Institute (NCI)

En fase III, randomisert klinisk studie av standard adjuvant endokrin terapi +/- kjemoterapi hos pasienter med 1-3 positive noder, hormonreseptorpositive og HER2-negative brystkreft med residivscore (RS) på 25 eller mindre. RxPONDER: A Clinical Trial Rx for positiv node, endokrin responsiv brystkreft

Denne randomiserte fase III kliniske studien studerer hvor godt tamoxifen citrat, anastrozol, letrozol eller exemestan med eller uten kjemoterapi virker i behandling av pasienter med brystkreft som har spredt seg fra der den begynte i brystet til omkringliggende normalt vev (invasiv). Østrogen kan forårsake vekst av brystkreftceller. Hormonbehandling, ved bruk av tamoxifen citrat, kan bekjempe brystkreft ved å blokkere bruken av østrogen av tumorcellene. Aromatasehemmere, som anastrozol, letrozol og exemestan, kan bekjempe brystkreft ved å redusere mengden østrogen kroppen lager. Legemidler som brukes i kjemoterapi virker på forskjellige måter for å stoppe veksten av tumorceller, enten ved å drepe cellene, ved å hindre dem i å dele seg, eller ved å hindre dem i å spre seg. Det er foreløpig ikke kjent om å gi tamoxifencitrat, anastrozol, letrozol eller exemestan er mer effektivt med kombinasjonskjemoterapi for behandling av pasienter med brystkreft.

Studieoversikt

Status

Aktiv, ikke rekrutterende

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

HOVEDMÅL:

I. Å bestemme effekten av kjemoterapi hos pasienter med nodepositiv brystkreft som ikke har høye residivskårer (RS) ved Oncotype DX.

SEKUNDÆRE MÅL:

I. For å sammenligne total overlevelse (OS), fjern sykdomsfri overlevelse (DDFS) og lokal sykdomsfri intervall (LDFI) ved mottak av kjemoterapi eller ikke og dets interaksjon med RS.

II. For å sammenligne toksisiteten på tvers av behandlingsarmene. III. For å utføre andre molekylære analyser eller teste andre signaturer som måler prognose og potensiell fordel ved kjemoterapi og sammenligne dem med Oncotype DX.

IV. For å bestemme virkningen av behandling med Oncotype DX på pasientrapportert angst (co-primært helserelatert livskvalitetsresultat [HRQL]) før screening, etter avsløring av testresultater og under den randomiserte studien.

V. For å bestemme innvirkningen av Oncotype DX på de initiale administrasjonskostnadene for nodepositiv, hormonreseptor (HR)-positiv, human epidermal vekstfaktorreseptor 2 (HER2)-negativ brystkreft.

VI. For å sammenligne pasientrapporterte hjelpemidler (f.eks. livskvalitet [QOL]) for de som er randomisert til kjemoterapi versus ingen kjemoterapi.

VII. Ved å bruke modellering og DFS-informasjon fra studien, for å estimere kostnadseffektiviteten til behandling med Oncotype DX kontra vanlig pleie.

VIII. For å bestemme rollen til andre analyser som prediktorer for DFS, DDFS og LDFI for pasienter randomisert til kjemoterapi versus ingen kjemoterapi.

IX. For å bestemme virkningen av behandling med kjemoterapi versus ingen kjemoterapi på pasientrapportert tretthet og kognitive bekymringer (sekundære HRQL-utfall).

X. For å bestemme virkningen av behandling med Oncotype DX på pasientrapportert beslutningskonflikt, oppfatninger angående Oncotype DX-testing og overlevendes bekymringer før screening, etter avsløring av testresultater og under den randomiserte studien (sekundære HRQL-utfall).

XI. Tilstedeværelsen av sirkulerende tumorceller (CTC+) ved bruk av to CTC-plattformer vil bli vurdert ved opptil to tidspunkter for å vurdere sent residiv hos de som fortsatt er i fare for det primære utfallet.

XII. For å sammenligne klinisk rapportert menopausal status med status kategorisert etter serumhormonnivåer bestemt fra baseline serum hos kvinner under 55 år og for å vurdere påfølgende assosiasjon med utfall.

BANKENS MÅL:

I. Til bankprøver for fremtidige korrelative studier.

OVERSIKT: Pasienter er randomisert til 1 av 2 behandlingsarmer.

ARM I: Pasienter får et protokoll-godkjent kjemoterapiregime basert på pasientens og/eller legens preferanser. Pasienter får deretter en protokollgodkjent adjuvant endokrin terapi som omfatter tamoxifencitrat, en aromatasehemmer (anastrozol, letrozol eller exemestan), eller begge i 5-10 år i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

ARM II: Pasienter får en protokoll-godkjent endokrin behandling som omfatter tamoxifen citrat, en aromatasehemmer (anastrozol, letrozol eller exemestan), eller begge i 5-10 år i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

Etter avsluttet studiebehandling følges pasientene opp hver 3. måned i 1 år, hver 6. måned i 4 år, og deretter årlig i 15 år.

Studietype

Intervensjonell

Registrering (Faktiske)

5018

Fase

Fase 3

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Canada
- British Columbia
  - Abbotsford, British Columbia, Canada, V2S 1K2
    - BCCA-Abbotsford Cancer Centre
  - Kelowna, British Columbia, Canada, V1Y 5L3
    - BCCA-Cancer Centre for the Southern Interior
  - Surrey, British Columbia, Canada, V3V 1Z2
    - BCCA-Fraser Valley Cancer Centre
  - Vancouver, British Columbia, Canada, V5Z 4E6
    - BCCA-Vancouver Cancer Centre
- Manitoba
  - Winnipeg, Manitoba, Canada, R3E 0V9
    - CancerCare Manitoba
- New Brunswick
  - Saint John, New Brunswick, Canada, E2L 4L2
    - Atlantic Health Sciences Corporation-Saint John Regional Hospital
- Newfoundland and Labrador
  - St. John's, Newfoundland and Labrador, Canada, A1B 3V6
    - Doctor H. Bliss Murphy Cancer Centre
- Ontario
  - Barrie, Ontario, Canada, L4M 6M2
    - Royal Victoria Regional Health Centre
  - Hamilton, Ontario, Canada, L8V 5C2
    - Juravinski Cancer Centre at Hamilton Health Sciences
  - Kitchener, Ontario, Canada, N2G 1G3
    - Grand River Regional Cancer Centre at Grand River Hospital
  - Mississauga, Ontario, Canada, L5M 2N1
    - Trillium Health Partners - Credit Valley Hospital
  - Sudbury, Ontario, Canada, P3E 5J1
    - Health Sciences North
  - Thunder Bay, Ontario, Canada, P7B 6V4
    - Thunder Bay Regional Health Science Centre
  - Toronto, Ontario, Canada, M5G 2M9
    - University Health Network-Princess Margaret Hospital
  - Toronto, Ontario, Canada, M5G 1X5
    - Mount Sinai Hospital
  - Toronto, Ontario, Canada, M4C 3E7
    - Michael Garron Hospital
  - Toronto, Ontario, Canada, M9C 1A5
    - Trillium Health Partners - Queensway Health Centre
- Prince Edward Island
  - Charlottetown, Prince Edward Island, Canada, C1A 8T5
    - PEI Cancer Treatment Centre-Queen Elizabeth Hospital
- Quebec
  - Montreal, Quebec, Canada, H3T 1E2
    - Jewish General Hospital
  - Montreal, Quebec, Canada, H3H 2R9
    - The Research Institute of the McGill University Health Centre (MUHC)
  - Montreal, Quebec, Canada, H2W 1S6
    - McGill University Department of Oncology
  - Montreal, Quebec, Canada, H2W 1T8
    - CHUM-Hotel Dieu de Montreal
  - Montreal, Quebec, Canada, H2X 3E4
    - CHUM - Centre Hospitalier de l'Universite de Montreal
  - Montreal, Quebec, Canada, H1T 2M4
    - CIUSSSEMTL-Hopital Maisonneuve-Rosemont
  - Quebec City, Quebec, Canada, G1S 4L8
    - CHU de Quebec-Hopital du Saint-Sacrement (HSS)
  - Sherbrooke, Quebec, Canada, J1H 5N4
    - Centre Hospitalier Universitaire de Sherbrooke-Fleurimont
- Saskatchewan
  - Regina, Saskatchewan, Canada, S4T 7T1
    - Allan Blair Cancer Centre
  - Saskatoon, Saskatchewan, Canada, S7N 4H4
    - Saskatoon Cancer Centre
Colombia
- - Bogota, Colombia, 99999
    - Instituto Nacional De Cancerologia
Forente stater
- Alabama
  - Anniston, Alabama, Forente stater, 36202
    - Northeast Alabama Regional Medical Center
  - Birmingham, Alabama, Forente stater, 35233
    - University of Alabama at Birmingham Cancer Center
  - Mobile, Alabama, Forente stater, 36688
    - University of South Alabama Mitchell Cancer Institute
  - Mobile, Alabama, Forente stater, 36608
    - Providence Hospital
- Alaska
  - Anchorage, Alaska, Forente stater, 98508
    - Anchorage Associates in Radiation Medicine
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Breast Care and Surgery LLC
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Oncology and Hematology LLC
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Women's Cancer Care
  - Anchorage, Alaska, Forente stater, 99508
    - Anchorage Oncology Centre
  - Anchorage, Alaska, Forente stater, 99508
    - Katmai Oncology Group
  - Anchorage, Alaska, Forente stater, 99508
    - Providence Alaska Medical Center
  - Anchorage, Alaska, Forente stater, 99504
    - Anchorage Radiation Therapy Center
  - Anchorage, Alaska, Forente stater, 99508
    - Alaska Regional Hospital
  - Fairbanks, Alaska, Forente stater, 99701
    - Fairbanks Memorial Hospital
- Arizona
  - Scottsdale, Arizona, Forente stater, 85258
    - Virginia G Piper Cancer Care-Del Camino
- Arkansas
  - Fort Smith, Arkansas, Forente stater, 72903
    - Mercy Hospital Fort Smith
  - Hot Springs, Arkansas, Forente stater, 71913
    - CHI Saint Vincent Cancer Center Hot Springs
  - Jonesboro, Arkansas, Forente stater, 72401
    - NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
  - Jonesboro, Arkansas, Forente stater, 72401
    - NEA Baptist Memorial Hospital
- California
  - Anaheim, California, Forente stater, 92806
    - Kaiser Permanente-Anaheim
  - Antioch, California, Forente stater, 94531
    - Kaiser Permanente-Deer Valley Medical Center
  - Antioch, California, Forente stater, 94531
    - East Bay Medical Oncology Hematology Medical Associates-Antioch
  - Arroyo Grande, California, Forente stater, 93420
    - PCR Oncology
  - Auburn, California, Forente stater, 95602
    - Sutter Auburn Faith Hospital
  - Auburn, California, Forente stater, 95603
    - Sutter Cancer Centers Radiation Oncology Services-Auburn
  - Baldwin Park, California, Forente stater, 91706
    - Kaiser Permanente-Baldwin Park
  - Bellflower, California, Forente stater, 90706
    - Kaiser Permanente-Bellflower
  - Berkeley, California, Forente stater, 94704
    - Alta Bates Summit Medical Center-Herrick Campus
  - Burbank, California, Forente stater, 91505
    - Providence Saint Joseph Medical Center/Disney Family Cancer Center
  - Burlingame, California, Forente stater, 94010
    - Mills-Peninsula Medical Center
  - Cameron Park, California, Forente stater, 95682
    - Sutter Cancer Centers Radiation Oncology Services-Cameron Park
  - Carmichael, California, Forente stater, 95608
    - Mercy San Juan Medical Center
  - Castro Valley, California, Forente stater, 94546
    - Eden Hospital Medical Center
  - Castro Valley, California, Forente stater, 94546
    - East Bay Radiation Oncology Center
  - Castro Valley, California, Forente stater, 94546
    - Valley Medical Oncology Consultants-Castro Valley
  - Clovis, California, Forente stater, 93611
    - Community Cancer Institute
  - Clovis, California, Forente stater, 93611
    - University Oncology Associates
  - Concord, California, Forente stater, 94520
    - John Muir Medical Center-Concord Campus
  - Costa Mesa, California, Forente stater, 92627
    - UC Irvine Health Cancer Center-Newport
  - Davis, California, Forente stater, 95616
    - Sutter Davis Hospital
  - Duarte, California, Forente stater, 91010
    - City of Hope Comprehensive Cancer Center
  - Dublin, California, Forente stater, 94568
    - Epic Care-Dublin
  - Emeryville, California, Forente stater, 94608
    - Bay Area Breast Surgeons Inc
  - Emeryville, California, Forente stater, 94608
    - Epic Care Partners in Cancer Care
  - Fontana, California, Forente stater, 92335
    - Kaiser Permanente-Fontana
  - Fremont, California, Forente stater, 94538
    - Kaiser Permanente-Fremont
  - Fremont, California, Forente stater, 94538
    - Valley Medical Oncology Consultants-Fremont
  - Fremont, California, Forente stater, 94538
    - Washington Hospital
  - Fremont, California, Forente stater, 94538
    - Palo Alto Medical Foundation-Fremont
  - Fresno, California, Forente stater, 93720
    - Kaiser Permanente-Fresno
  - Harbor City, California, Forente stater, 90710
    - Kaiser Permanente - Harbor City
  - Irvine, California, Forente stater, 92618
    - Kaiser Permanente-Irvine
  - La Jolla, California, Forente stater, 92093
    - UC San Diego Moores Cancer Center
  - Loma Linda, California, Forente stater, 92354
    - Loma Linda University Medical Center
  - Long Beach, California, Forente stater, 90806
    - Long Beach Memorial Medical Center-Todd Cancer Institute
  - Los Angeles, California, Forente stater, 90033
    - USC / Norris Comprehensive Cancer Center
  - Los Angeles, California, Forente stater, 90027
    - Kaiser Permanente Los Angeles Medical Center
  - Los Angeles, California, Forente stater, 90048
    - Cedars Sinai Medical Center
  - Los Angeles, California, Forente stater, 90034
    - Kaiser Permanente West Los Angeles
  - Los Angeles, California, Forente stater, 90033
    - Los Angeles General Medical Center
  - Martinez, California, Forente stater, 94553-3156
    - Contra Costa Regional Medical Center
  - Marysville, California, Forente stater, 95901
    - Fremont - Rideout Cancer Center
  - Merced, California, Forente stater, 95340
    - Mercy UC Davis Cancer Center
  - Modesto, California, Forente stater, 95355
    - Memorial Medical Center
  - Modesto, California, Forente stater, 95356
    - Kaiser Permanente-Modesto
  - Mountain View, California, Forente stater, 94040
    - El Camino Hospital
  - Mountain View, California, Forente stater, 94040
    - Palo Alto Medical Foundation-Camino Division
  - Mountain View, California, Forente stater, 94040
    - Palo Alto Medical Foundation-Gynecologic Oncology
  - Northridge, California, Forente stater, 91325
    - Northridge Hospital Medical Center
  - Novato, California, Forente stater, 94945
    - Sutter Cancer Research Consortium
  - Oakland, California, Forente stater, 94611
    - Kaiser Permanente-Oakland
  - Oakland, California, Forente stater, 94609
    - Alta Bates Summit Medical Center - Summit Campus
  - Oakland, California, Forente stater, 94609
    - Hematology and Oncology Associates-Oakland
  - Oakland, California, Forente stater, 94602
    - Highland General Hospital
  - Oakland, California, Forente stater, 94609
    - Tom K Lee Inc
  - Oakland, California, Forente stater, 94609
    - Bay Area Tumor Institute
  - Orange, California, Forente stater, 92868
    - UC Irvine Health/Chao Family Comprehensive Cancer Center
  - Orange, California, Forente stater, 92868
    - Saint Joseph Hospital - Orange
  - Palm Springs, California, Forente stater, 92262
    - Desert Regional Medical Center
  - Palo Alto, California, Forente stater, 94304
    - Stanford Cancer Institute Palo Alto
  - Palo Alto, California, Forente stater, 94301
    - Palo Alto Medical Foundation Health Care
  - Panorama City, California, Forente stater, 91402
    - Kaiser Permanente - Panorama City
  - Pasadena, California, Forente stater, 91105
    - Keck Medical Center of USC Pasadena
  - Pleasant Hill, California, Forente stater, 94523
    - East Bay Medical Oncology Hematology Medical Associates Inc-Pleasant Hill
  - Pleasant Hill, California, Forente stater, 94523
    - John Muir Health Cancer Medical Group
  - Pleasanton, California, Forente stater, 94588
    - Valley Medical Oncology Consultants
  - Pomona, California, Forente stater, 91767
    - Pomona Valley Hospital Medical Center
  - Redwood City, California, Forente stater, 94063
    - Kaiser Permanente-Redwood City
  - Richmond, California, Forente stater, 94801
    - Kaiser Permanente-Richmond
  - Riverside, California, Forente stater, 92505
    - Kaiser Permanente-Riverside
  - Roseville, California, Forente stater, 95661
    - Kaiser Permanente-Roseville
  - Roseville, California, Forente stater, 95661
    - Sutter Cancer Centers Radiation Oncology Services-Roseville
  - Roseville, California, Forente stater, 95661
    - Sutter Roseville Medical Center
  - Sacramento, California, Forente stater, 95816
    - Sutter Medical Center Sacramento
  - Sacramento, California, Forente stater, 95817
    - University of California Davis Comprehensive Cancer Center
  - Sacramento, California, Forente stater, 95823
    - Kaiser Permanente-South Sacramento
  - Sacramento, California, Forente stater, 95825
    - Kaiser Permanente - Sacramento
  - Salinas, California, Forente stater, 93901
    - Salinas Valley Memorial
  - San Diego, California, Forente stater, 92120
    - Kaiser Permanente-San Diego Zion
  - San Diego, California, Forente stater, 92108
    - Kaiser Permanente-San Diego Mission
  - San Diego, California, Forente stater, 92123
    - Sharp Memorial Hospital
  - San Francisco, California, Forente stater, 94115
    - Kaiser Permanente-San Francisco
  - San Francisco, California, Forente stater, 94115
    - California Pacific Medical Center-Pacific Campus
  - San Jose, California, Forente stater, 95119
    - Kaiser Permanente-Santa Teresa-San Jose
  - San Leandro, California, Forente stater, 94577
    - Kaiser Permanente San Leandro
  - San Leandro, California, Forente stater, 94578
    - East Bay Medical Oncology Hematology Associates Inc
  - San Marcos, California, Forente stater, 92078
    - Kaiser Permanente-San Marcos
  - San Pablo, California, Forente stater, 94806
    - Doctors Medical Center- JC Robinson Regional Cancer Center
  - San Rafael, California, Forente stater, 94903
    - Kaiser Permanente-San Rafael
  - Santa Clara, California, Forente stater, 95051
    - Kaiser Permanente Medical Center - Santa Clara
  - Santa Cruz, California, Forente stater, 95065
    - Palo Alto Medical Foundation-Santa Cruz
  - Santa Rosa, California, Forente stater, 95403
    - Kaiser Permanente-Santa Rosa
  - Santa Rosa, California, Forente stater, 95403
    - Sutter Pacific Medical Foundation
  - South San Francisco, California, Forente stater, 94080
    - Kaiser Permanente-South San Francisco
  - Stockton, California, Forente stater, 95210
    - Kaiser Permanente-Stockton
  - Sunnyvale, California, Forente stater, 94086
    - Palo Alto Medical Foundation-Sunnyvale
  - Sylmar, California, Forente stater, 91342
    - Olive View-University of California Los Angeles Medical Center
  - Vacaville, California, Forente stater, 95688
    - Kaiser Permanente Medical Center-Vacaville
  - Vacaville, California, Forente stater, 95687
    - Northbay Cancer Center
  - Vacaville, California, Forente stater, 95687
    - Sutter Cancer Centers Radiation Oncology Services-Vacaville
  - Vallejo, California, Forente stater, 94589
    - Kaiser Permanente-Vallejo
  - Vallejo, California, Forente stater, 94589
    - Sutter Solano Medical Center/Cancer Center
  - Walnut Creek, California, Forente stater, 94596
    - Kaiser Permanente-Walnut Creek
  - Walnut Creek, California, Forente stater, 94598
    - John Muir Medical Center-Walnut Creek
  - Whittier, California, Forente stater, 90602
    - Presbyterian Intercommunity Hospital
  - Woodland Hills, California, Forente stater, 91367
    - Kaiser Permanente-Woodland Hills
- Colorado
  - Alamosa, Colorado, Forente stater, 81101
    - San Luis Valley Regional Medical Center
  - Aurora, Colorado, Forente stater, 80012
    - Rocky Mountain Cancer Centers-Aurora
  - Aurora, Colorado, Forente stater, 80012
    - The Medical Center of Aurora
  - Aurora, Colorado, Forente stater, 80045
    - Rocky Mountain Regional VA Medical Center
  - Aurora, Colorado, Forente stater, 80045
    - UCHealth University of Colorado Hospital
  - Boulder, Colorado, Forente stater, 80301
    - Boulder Community Hospital
  - Boulder, Colorado, Forente stater, 80304
    - Rocky Mountain Cancer Centers-Boulder
  - Colorado Springs, Colorado, Forente stater, 80907
    - Penrose-Saint Francis Healthcare
  - Colorado Springs, Colorado, Forente stater, 80909
    - UCHealth Memorial Hospital Central
  - Colorado Springs, Colorado, Forente stater, 80907
    - Rocky Mountain Cancer Centers-Penrose
  - Denver, Colorado, Forente stater, 80210
    - Porter Adventist Hospital
  - Denver, Colorado, Forente stater, 80205
    - Kaiser Permanente-Franklin
  - Denver, Colorado, Forente stater, 80218
    - Presbyterian - Saint Lukes Medical Center - Health One
  - Denver, Colorado, Forente stater, 80218
    - SCL Health Saint Joseph Hospital
  - Denver, Colorado, Forente stater, 80220
    - Rose Medical Center
  - Denver, Colorado, Forente stater, 80218
    - Rocky Mountain Cancer Centers-Midtown
  - Denver, Colorado, Forente stater, 80220
    - Rocky Mountain Cancer Centers-Rose
  - Denver, Colorado, Forente stater, 80218
    - Colorado Blood Cancer Institute
  - Denver, Colorado, Forente stater, 80222
    - Western States Cancer Research NCORP
  - Durango, Colorado, Forente stater, 81301
    - Mercy Medical Center
  - Durango, Colorado, Forente stater, 81301
    - Southwest Oncology PC
  - Edwards, Colorado, Forente stater, 81632
    - Shaw Cancer Center
  - Englewood, Colorado, Forente stater, 80113
    - Mountain Blue Cancer Care Center - Swedish
  - Englewood, Colorado, Forente stater, 80113
    - Swedish Medical Center
  - Fort Collins, Colorado, Forente stater, 80524
    - Poudre Valley Hospital
  - Glenwood Springs, Colorado, Forente stater, 81601
    - Valley View Hospital Cancer Center
  - Golden, Colorado, Forente stater, 80401
    - Mountain Blue Cancer Care Center
  - Grand Junction, Colorado, Forente stater, 81501
    - Saint Mary's Hospital and Regional Medical Center
  - Greeley, Colorado, Forente stater, 80631
    - North Colorado Medical Center
  - Greenwood Village, Colorado, Forente stater, 80111
    - Rocky Mountain Cancer Centers-Greenwood Village
  - Lafayette, Colorado, Forente stater, 80026
    - Kaiser Permanente-Rock Creek
  - Lakewood, Colorado, Forente stater, 80228
    - Saint Anthony Hospital
  - Lakewood, Colorado, Forente stater, 80228
    - Rocky Mountain Cancer Centers-Lakewood
  - Littleton, Colorado, Forente stater, 80120
    - Rocky Mountain Cancer Centers-Littleton
  - Littleton, Colorado, Forente stater, 80122
    - Littleton Adventist Hospital
  - Lone Tree, Colorado, Forente stater, 80124
    - Kaiser Permanente-Lone Tree
  - Lone Tree, Colorado, Forente stater, 80124
    - Sky Ridge Medical Center
  - Lone Tree, Colorado, Forente stater, 80124
    - Rocky Mountain Cancer Centers-Sky Ridge
  - Longmont, Colorado, Forente stater, 80501
    - Longmont United Hospital
  - Longmont, Colorado, Forente stater, 80501
    - Rocky Mountain Cancer Centers-Longmont
  - Loveland, Colorado, Forente stater, 80539
    - McKee Medical Center
  - Montrose, Colorado, Forente stater, 81401
    - Montrose Memorial Hospital
  - Parker, Colorado, Forente stater, 80138
    - Parker Adventist Hospital
  - Parker, Colorado, Forente stater, 80138
    - Rocky Mountain Cancer Centers-Parker
  - Pueblo, Colorado, Forente stater, 81004
    - Saint Mary Corwin Medical Center
  - Pueblo, Colorado, Forente stater, 81008
    - Rocky Mountain Cancer Centers - Pueblo
  - Thornton, Colorado, Forente stater, 80260
    - Rocky Mountain Cancer Centers-Thornton
  - Thornton, Colorado, Forente stater, 80229
    - North Suburban Medical Center
  - Wheat Ridge, Colorado, Forente stater, 80033
    - SCL Health Lutheran Medical Center
- Connecticut
  - Bridgeport, Connecticut, Forente stater, 06610
    - Bridgeport Hospital
  - Danbury, Connecticut, Forente stater, 06810
    - Danbury Hospital
  - Derby, Connecticut, Forente stater, 06418
    - Smilow Cancer Hospital-Derby Care Center
  - Fairfield, Connecticut, Forente stater, 06824
    - Smilow Cancer Hospital Care Center-Fairfield
  - Farmington, Connecticut, Forente stater, 06030
    - University of Connecticut
  - Greenwich, Connecticut, Forente stater, 06830
    - Greenwich Hospital
  - Guilford, Connecticut, Forente stater, 06437
    - Smilow Cancer Hospital Care Center - Guilford
  - Hartford, Connecticut, Forente stater, 06105
    - Smilow Cancer Hospital Care Center at Saint Francis
  - Hartford, Connecticut, Forente stater, 06102
    - Hartford Hospital
  - Manchester, Connecticut, Forente stater, 06040
    - Manchester Memorial Hospital
  - Middletown, Connecticut, Forente stater, 06457
    - Middlesex Hospital
  - New Britain, Connecticut, Forente stater, 06050
    - The Hospital of Central Connecticut
  - New Haven, Connecticut, Forente stater, 06520
    - Yale University
  - New Haven, Connecticut, Forente stater, 06511
    - Yale-New Haven Hospital Saint Raphael Campus
  - North Haven, Connecticut, Forente stater, 06473
    - Yale-New Haven Hospital North Haven Medical Center
  - Norwalk, Connecticut, Forente stater, 06856
    - Norwalk Hospital
  - Norwich, Connecticut, Forente stater, 06360
    - Eastern Connecticut Hematology and Oncology Associates
  - Orange, Connecticut, Forente stater, 06477
    - Smilow Cancer Hospital-Orange Care Center
  - Torrington, Connecticut, Forente stater, 06790
    - Smilow Cancer Hospital-Torrington Care Center
  - Trumbull, Connecticut, Forente stater, 06611
    - Smilow Cancer Hospital Care Center-Trumbull
  - Waterbury, Connecticut, Forente stater, 06708
    - Smilow Cancer Hospital-Waterbury Care Center
  - Waterbury, Connecticut, Forente stater, 06708
    - Harold Leever Regional Cancer Center
  - Waterford, Connecticut, Forente stater, 06385
    - Smilow Cancer Hospital Care Center - Waterford
- Delaware
  - Dover, Delaware, Forente stater, 19901
    - Bayhealth Hospital Kent Campus
  - Lewes, Delaware, Forente stater, 19958
    - Beebe Medical Center
  - Milford, Delaware, Forente stater, 19963
    - Bayhealth Hospital Sussex Campus
  - Newark, Delaware, Forente stater, 19713
    - Helen F Graham Cancer Center
  - Newark, Delaware, Forente stater, 19713
    - Delaware Clinical and Laboratory Physicians PA
  - Newark, Delaware, Forente stater, 19713
    - Medical Oncology Hematology Consultants PA
  - Newark, Delaware, Forente stater, 19718
    - Christiana Care Health System-Christiana Hospital
  - Newark, Delaware, Forente stater, 19713
    - Christiana Gynecologic Oncology LLC
  - Rehoboth Beach, Delaware, Forente stater, 19971
    - Beebe Health Campus
  - Seaford, Delaware, Forente stater, 19973
    - TidalHealth Nanticoke / Allen Cancer Center
  - Wilmington, Delaware, Forente stater, 19801
    - Christiana Care Health System-Wilmington Hospital
- District of Columbia
  - Washington, District of Columbia, Forente stater, 20010
    - MedStar Washington Hospital Center
  - Washington, District of Columbia, Forente stater, 20007
    - MedStar Georgetown University Hospital
  - Washington, District of Columbia, Forente stater, 20016
    - Sibley Memorial Hospital
  - Washington, District of Columbia, Forente stater, 20002
    - Kaiser Permanente-Capitol Hill Medical Center
  - Washington, District of Columbia, Forente stater, 20037
    - George Washington University Medical Center
- Florida
  - Aventura, Florida, Forente stater, 33180
    - Mount Sinai Comprehensive Cancer Center at Aventura
  - Boca Raton, Florida, Forente stater, 33486
    - Boca Raton Regional Hospital
  - Clearwater, Florida, Forente stater, 33756
    - Morton Plant Hospital
  - Daytona Beach, Florida, Forente stater, 32114
    - Halifax Health Medical Center-Centers for Oncology
  - Daytona Beach, Florida, Forente stater, 32117
    - Florida Hospital Memorial Medical Center
  - Deerfield Beach, Florida, Forente stater, 33064
    - Broward Health North
  - Fort Lauderdale, Florida, Forente stater, 33308
    - Holy Cross Hospital
  - Gainesville, Florida, Forente stater, 32610
    - University of Florida Health Science Center - Gainesville
  - Jacksonville, Florida, Forente stater, 32207
    - Baptist MD Anderson Cancer Center
  - Jacksonville, Florida, Forente stater, 32224-9980
    - Mayo Clinic in Florida
  - Jacksonville, Florida, Forente stater, 32204
    - Saint Vincent's Medical Center
  - Jupiter, Florida, Forente stater, 33458
    - Jupiter Medical Center
  - Lakeland, Florida, Forente stater, 33805
    - The Watson Clinic
  - Miami, Florida, Forente stater, 33136
    - University of Miami Miller School of Medicine-Sylvester Cancer Center
  - Miami, Florida, Forente stater, 33176
    - Miami Cancer Institute
  - Miami, Florida, Forente stater, 33176
    - Advanced Medical Specialties -North
  - Miami Beach, Florida, Forente stater, 33140
    - Mount Sinai Medical Center
  - Orlando, Florida, Forente stater, 32806
    - Orlando Health Cancer Institute
  - Pensacola, Florida, Forente stater, 32504
    - Sacred Heart Hospital
  - Tampa, Florida, Forente stater, 33607
    - Saint Joseph's Hospital/Children's Hospital-Tampa
  - Titusville, Florida, Forente stater, 32796
    - Space Coast Cancer Centers-Titusville
  - Weston, Florida, Forente stater, 33331
    - Cleveland Clinic-Weston
- Georgia
  - Albany, Georgia, Forente stater, 31701
    - Phoebe Putney Memorial Hospital
  - Atlanta, Georgia, Forente stater, 30308
    - Emory University Hospital Midtown
  - Atlanta, Georgia, Forente stater, 30322
    - Emory University Hospital/Winship Cancer Institute
  - Atlanta, Georgia, Forente stater, 30342
    - Emory Saint Joseph's Hospital
  - Atlanta, Georgia, Forente stater, 30303
    - Grady Health System
  - Atlanta, Georgia, Forente stater, 30309
    - Piedmont Hospital
  - Atlanta, Georgia, Forente stater, 30342
    - Northside Hospital
  - Atlanta, Georgia, Forente stater, 30342
    - Atlanta Regional CCOP
  - Augusta, Georgia, Forente stater, 30912
    - Augusta University Medical Center
  - Austell, Georgia, Forente stater, 30106
    - WellStar Cobb Hospital
  - Columbus, Georgia, Forente stater, 31904
    - John B Amos Cancer Center
  - Cumming, Georgia, Forente stater, 30041
    - Northside Hospital-Forsyth
  - Decatur, Georgia, Forente stater, 30033
    - Dekalb Medical Center
  - Dublin, Georgia, Forente stater, 31021
    - Dublin Hematology Oncology Care PC
  - Fayetteville, Georgia, Forente stater, 30214
    - Piedmont Fayette Hospital
  - Gainesville, Georgia, Forente stater, 30501
    - Northeast Georgia Medical Center-Gainesville
  - Lawrenceville, Georgia, Forente stater, 30046
    - Northside Hospital - Gwinnett
  - Macon, Georgia, Forente stater, 31201
    - Medical Center of Central Georgia
  - Marietta, Georgia, Forente stater, 30060
    - WellStar Kennestone Hospital
  - Riverdale, Georgia, Forente stater, 30274
    - Southern Regional Medical Center
  - Rome, Georgia, Forente stater, 30165
    - Harbin Clinic Medical Oncology and Clinical Research
  - Savannah, Georgia, Forente stater, 31405
    - Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
  - Savannah, Georgia, Forente stater, 31404
    - Memorial Health University Medical Center
  - Savannah, Georgia, Forente stater, 31404
    - Summit Cancer Care-Memorial
  - Savannah, Georgia, Forente stater, 31404
    - Low Country Cancer Care
  - Valdosta, Georgia, Forente stater, 31602
    - South Georgia Medical Center/Pearlman Cancer Center
- Hawaii
  - 'Aiea, Hawaii, Forente stater, 96701
    - Pali Momi Medical Center
  - 'Aiea, Hawaii, Forente stater, 96701
    - Queen's Cancer Center - Pearlridge
  - Honolulu, Hawaii, Forente stater, 96813
    - Queen's Medical Center
  - Honolulu, Hawaii, Forente stater, 96817
    - The Cancer Center of Hawaii-Liliha
  - Honolulu, Hawaii, Forente stater, 96813
    - Hawaii Cancer Care Inc - Waterfront Plaza
  - Honolulu, Hawaii, Forente stater, 96813
    - Straub Clinic and Hospital
  - Honolulu, Hawaii, Forente stater, 96813
    - University of Hawaii Cancer Center
  - Honolulu, Hawaii, Forente stater, 96817
    - Queen's Cancer Center - Kuakini
  - Honolulu, Hawaii, Forente stater, 96826
    - Kapiolani Medical Center for Women and Children
  - Honolulu, Hawaii, Forente stater, 96819
    - Kaiser Permanente Moanalua Medical Center
  - Honolulu, Hawaii, Forente stater, 96859
    - Tripler Army Medical Center
  - Kailua, Hawaii, Forente stater, 96734
    - Castle Medical Center
  - Lihue, Hawaii, Forente stater, 96766
    - Wilcox Memorial Hospital and Kauai Medical Clinic
  - Wailuku, Hawaii, Forente stater, 96793
    - Maui Memorial Medical Center
  - Wailuku, Hawaii, Forente stater, 96793
    - Pacific Cancer Institute of Maui
- Idaho
  - Boise, Idaho, Forente stater, 83706
    - Saint Alphonsus Cancer Care Center-Boise
  - Boise, Idaho, Forente stater, 83712
    - Saint Luke's Cancer Institute - Boise
  - Caldwell, Idaho, Forente stater, 83605
    - Saint Alphonsus Cancer Care Center-Caldwell
  - Coeur d'Alene, Idaho, Forente stater, 83814
    - Kootenai Health - Coeur d'Alene
  - Emmett, Idaho, Forente stater, 83617
    - Walter Knox Memorial Hospital
  - Fruitland, Idaho, Forente stater, 83619
    - Saint Luke's Cancer Institute - Fruitland
  - Lewiston, Idaho, Forente stater, 83501
    - Saint Joseph Regional Medical Center
  - Meridian, Idaho, Forente stater, 83642
    - Idaho Urologic Institute-Meridian
  - Meridian, Idaho, Forente stater, 83642
    - Saint Luke's Cancer Institute - Meridian
  - Nampa, Idaho, Forente stater, 83686
    - Saint Luke's Cancer Institute - Nampa
  - Nampa, Idaho, Forente stater, 83687
    - Saint Alphonsus Cancer Care Center-Nampa
  - Post Falls, Idaho, Forente stater, 83854
    - Kootenai Clinic Cancer Services - Post Falls
  - Sandpoint, Idaho, Forente stater, 83864
    - Kootenai Cancer Clinic
  - Twin Falls, Idaho, Forente stater, 83301
    - Saint Luke's Cancer Institute - Twin Falls
- Illinois
  - Alton, Illinois, Forente stater, 62002
    - Saint Anthony's Health
  - Aurora, Illinois, Forente stater, 60504
    - Rush - Copley Medical Center
  - Berwyn, Illinois, Forente stater, 60402
    - Mac Neal Hospital
  - Bloomington, Illinois, Forente stater, 61704
    - Illinois CancerCare-Bloomington
  - Bloomington, Illinois, Forente stater, 61701
    - Saint Joseph Medical Center
  - Canton, Illinois, Forente stater, 61520
    - Illinois CancerCare-Canton
  - Canton, Illinois, Forente stater, 61520
    - Graham Hospital Association
  - Carbondale, Illinois, Forente stater, 62902
    - Memorial Hospital of Carbondale
  - Carthage, Illinois, Forente stater, 62321
    - Illinois CancerCare-Carthage
  - Carthage, Illinois, Forente stater, 62321
    - Memorial Hospital
  - Centralia, Illinois, Forente stater, 62801
    - Centralia Oncology Clinic
  - Chicago, Illinois, Forente stater, 60611
    - Northwestern University
  - Chicago, Illinois, Forente stater, 60637
    - University of Chicago Comprehensive Cancer Center
  - Chicago, Illinois, Forente stater, 60612
    - University of Illinois
  - Chicago, Illinois, Forente stater, 60612
    - John H Stroger Jr Hospital of Cook County
  - Chicago, Illinois, Forente stater, 60608
    - Mount Sinai Hospital Medical Center
  - Chicago, Illinois, Forente stater, 60611
    - Hematology and Oncology Associates
  - Chicago, Illinois, Forente stater, 60631
    - Presence Resurrection Medical Center
  - Chicago, Illinois, Forente stater, 60640
    - Weiss Memorial Hospital
  - Danville, Illinois, Forente stater, 61832
    - Carle at The Riverfront
  - DeKalb, Illinois, Forente stater, 60115
    - Northwestern Medicine Cancer Center Kishwaukee
  - Decatur, Illinois, Forente stater, 62526
    - Decatur Memorial Hospital
  - Decatur, Illinois, Forente stater, 62526
    - Cancer Care Specialists of Illinois - Decatur
  - Decatur, Illinois, Forente stater, 62526
    - Heartland Cancer Research NCORP
  - Downers Grove, Illinois, Forente stater, 60515
    - Advocate Good Samaritan Hospital
  - Effingham, Illinois, Forente stater, 62401
    - Crossroads Cancer Center
  - Effingham, Illinois, Forente stater, 62401
    - Carle Physician Group-Effingham
  - Elgin, Illinois, Forente stater, 60123
    - Advocate Sherman Hospital
  - Elmhurst, Illinois, Forente stater, 60126
    - Elmhurst Memorial Hospital
  - Eureka, Illinois, Forente stater, 61530
    - Illinois CancerCare-Eureka
  - Eureka, Illinois, Forente stater, 61530
    - Eureka Hospital
  - Evanston, Illinois, Forente stater, 60202
    - Saint Francis Hospital
  - Freeport, Illinois, Forente stater, 61032
    - Freeport Memorial Hospital/Leonard C Ferguson Cancer Center
  - Galesburg, Illinois, Forente stater, 61401
    - Western Illinois Cancer Treatment Center
  - Galesburg, Illinois, Forente stater, 61401
    - Illinois CancerCare-Galesburg
  - Harvey, Illinois, Forente stater, 60426
    - Ingalls Memorial Hospital
  - Havana, Illinois, Forente stater, 62644
    - Mason District Hospital
  - Havana, Illinois, Forente stater, 62644
    - Illinois CancerCare-Havana
  - Highland Park, Illinois, Forente stater, 60035
    - Hematology Oncology Associates of Illinois-Highland Park
  - Hinsdale, Illinois, Forente stater, 60521
    - AMITA Health Cancer Institute and Outpatient Center
  - Hinsdale, Illinois, Forente stater, 60521
    - Hinsdale Hematology Oncology Associates Incorporated
  - Kankakee, Illinois, Forente stater, 60901
    - Presence Saint Mary's Hospital
  - Kewanee, Illinois, Forente stater, 61443
    - Illinois CancerCare-Kewanee Clinic
  - La Grange, Illinois, Forente stater, 60525
    - AMITA Health Adventist Medical Center
  - Libertyville, Illinois, Forente stater, 60048
    - AMG Libertyville - Oncology
  - Macomb, Illinois, Forente stater, 61455
    - Illinois CancerCare-Macomb
  - Macomb, Illinois, Forente stater, 61455
    - Mcdonough District Hospital
  - Mattoon, Illinois, Forente stater, 61938
    - Carle Physician Group-Mattoon/Charleston
  - Maywood, Illinois, Forente stater, 60153
    - Loyola University Medical Center
  - Moline, Illinois, Forente stater, 61265
    - Garneau, Stewart C MD (UIA Investigator)
  - Moline, Illinois, Forente stater, 61265
    - Porubcin, Michael MD (UIA Investigator)
  - Moline, Illinois, Forente stater, 61265
    - Spector, David MD (UIA Investigator)
  - Moline, Illinois, Forente stater, 61265
    - Trinity Medical Center
  - Monmouth, Illinois, Forente stater, 61462
    - Illinois CancerCare-Monmouth
  - Monmouth, Illinois, Forente stater, 61462
    - Holy Family Medical Center
  - Mount Vernon, Illinois, Forente stater, 62864
    - Good Samaritan Regional Health Center
  - Naperville, Illinois, Forente stater, 60540
    - Edward Hospital/Cancer Center
  - New Lenox, Illinois, Forente stater, 60451
    - UC Comprehensive Cancer Center at Silver Cross
  - Niles, Illinois, Forente stater, 60714
    - Illinois Cancer Specialists-Niles
  - Normal, Illinois, Forente stater, 61761
    - Carle Cancer Institute Normal
  - Normal, Illinois, Forente stater, 61761
    - Bromenn Regional Medical Center
  - Normal, Illinois, Forente stater, 61761
    - Illinois CancerCare-Community Cancer Center
  - Normal, Illinois, Forente stater, 61761
    - Mid-Illinois Hematology Oncology Associates Limited
  - O'Fallon, Illinois, Forente stater, 62269
    - Cancer Care Center of O'Fallon
  - Oak Lawn, Illinois, Forente stater, 60453-2699
    - Advocate Christ Medical Center
  - Ottawa, Illinois, Forente stater, 61350
    - Illinois CancerCare-Ottawa Clinic
  - Ottawa, Illinois, Forente stater, 61350
    - Radiation Oncology of Northern Illinois
  - Ottawa, Illinois, Forente stater, 61350
    - Ottawa Regional Hospital and Healthcare Center
  - Park Ridge, Illinois, Forente stater, 60068
    - Advocate Lutheran General Hospital
  - Pekin, Illinois, Forente stater, 61554
    - Illinois CancerCare-Pekin
  - Pekin, Illinois, Forente stater, 61554
    - OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
  - Peoria, Illinois, Forente stater, 61636
    - Methodist Medical Center of Illinois
  - Peoria, Illinois, Forente stater, 61637
    - OSF Saint Francis Medical Center
  - Peoria, Illinois, Forente stater, 61615
    - Illinois CancerCare-Peoria
  - Peoria, Illinois, Forente stater, 61615
    - OSF Saint Francis Radiation Oncology at Peoria Cancer Center
  - Peoria, Illinois, Forente stater, 61614
    - Proctor Hospital
  - Peru, Illinois, Forente stater, 61354
    - Illinois CancerCare-Peru
  - Peru, Illinois, Forente stater, 61354
    - Valley Radiation Oncology
  - Peru, Illinois, Forente stater, 61354
    - Illinois Valley Hospital
  - Princeton, Illinois, Forente stater, 61356
    - Illinois CancerCare-Princeton
  - Princeton, Illinois, Forente stater, 61356
    - Perry Memorial Hospital
  - River Forest, Illinois, Forente stater, 60305
    - West Suburban Medical Center
  - Rockford, Illinois, Forente stater, 61114
    - SwedishAmerican Regional Cancer Center/ACT
  - Rockford, Illinois, Forente stater, 61104
    - Swedish American Hospital
  - Skokie, Illinois, Forente stater, 60076
    - Hematology Oncology Associates of Illinois - Skokie
  - Spring Valley, Illinois, Forente stater, 61362
    - Illinois CancerCare-Spring Valley
  - Springfield, Illinois, Forente stater, 62781
    - Memorial Medical Center
  - Springfield, Illinois, Forente stater, 62702
    - Southern Illinois University School of Medicine
  - Springfield, Illinois, Forente stater, 62702
    - Springfield Clinic
  - Springfield, Illinois, Forente stater, 62702
    - Central Illinois Hematology Oncology Center
  - Urbana, Illinois, Forente stater, 61801
    - Carle Cancer Center
  - Urbana, Illinois, Forente stater, 61801
    - The Carle Foundation Hospital
  - Yorkville, Illinois, Forente stater, 60560
    - Rush-Copley Healthcare Center
- Indiana
  - Beech Grove, Indiana, Forente stater, 46107
    - Franciscan Saint Francis Health-Beech Grove
  - Carmel, Indiana, Forente stater, 46032
    - IU Health North Hospital
  - Crown Point, Indiana, Forente stater, 46307
    - Michiana Hematology Oncology PC-Crown Point
  - Elkhart, Indiana, Forente stater, 46515
    - Elkhart General Hospital
  - Elkhart, Indiana, Forente stater, 46514
    - Michiana Hematology Oncology PC-Elkhart
  - Elkhart, Indiana, Forente stater, 46514-2098
    - Elkhart Clinic
  - Evansville, Indiana, Forente stater, 47713
    - Deaconess Clinic Downtown
  - Fort Wayne, Indiana, Forente stater, 46845
    - Fort Wayne Medical Oncology and Hematology Inc-Parkview
  - Indianapolis, Indiana, Forente stater, 46237
    - Franciscan Health Indianapolis
  - Indianapolis, Indiana, Forente stater, 46202
    - Indiana University/Melvin and Bren Simon Cancer Center
  - Indianapolis, Indiana, Forente stater, 46202
    - Sidney and Lois Eskenazi Hospital
  - Indianapolis, Indiana, Forente stater, 46219
    - IU Health Central Indiana Cancer Centers-East
  - Indianapolis, Indiana, Forente stater, 46290
    - Springmill Medical Center
  - Indianapolis, Indiana, Forente stater, 46202
    - IU Health Methodist Hospital
  - Kokomo, Indiana, Forente stater, 46904
    - Community Howard Regional Health
  - La Porte, Indiana, Forente stater, 46350
    - IU Health La Porte Hospital
  - Lafayette, Indiana, Forente stater, 47904
    - IU Health Arnett Cancer Care
  - Merrillville, Indiana, Forente stater, 46410
    - Premier Oncology Hematology Associates
  - Michigan City, Indiana, Forente stater, 46360
    - Franciscan Saint Anthony Health-Michigan City
  - Michigan City, Indiana, Forente stater, 46360
    - Woodland Cancer Care Center
  - Mishawaka, Indiana, Forente stater, 46545
    - Memorial Regional Cancer Center Day Road
  - Mishawaka, Indiana, Forente stater, 46545
    - Michiana Hematology Oncology PC-Mishawaka
  - Mishawaka, Indiana, Forente stater, 46545
    - Saint Joseph Regional Medical Center-Mishawaka
  - Muncie, Indiana, Forente stater, 47303
    - IU Health Ball Memorial Hospital
  - Newburgh, Indiana, Forente stater, 47630
    - Chancellor Center for Oncology
  - Plymouth, Indiana, Forente stater, 46563
    - Michiana Hematology Oncology PC-Plymouth
  - Richmond, Indiana, Forente stater, 47374
    - Reid Health
  - South Bend, Indiana, Forente stater, 46601
    - Memorial Hospital of South Bend
  - South Bend, Indiana, Forente stater, 46601
    - Michiana Hematology Oncology PC-South Bend
  - South Bend, Indiana, Forente stater, 46628
    - Northern Indiana Cancer Research Consortium
  - South Bend, Indiana, Forente stater, 46617
    - South Bend Clinic
  - Valparaiso, Indiana, Forente stater, 46383
    - Porter Memorial Hospital
  - Westville, Indiana, Forente stater, 46391
    - Michiana Hematology Oncology PC-Westville
- Iowa
  - Ames, Iowa, Forente stater, 50010
    - Mary Greeley Medical Center
  - Ames, Iowa, Forente stater, 50010
    - McFarland Clinic - Ames
  - Bettendorf, Iowa, Forente stater, 52722
    - Constantinou, Costas L MD (UIA Investigator)
  - Boone, Iowa, Forente stater, 50036
    - McFarland Clinic - Boone
  - Cedar Rapids, Iowa, Forente stater, 52403
    - Mercy Hospital
  - Cedar Rapids, Iowa, Forente stater, 52403
    - Oncology Associates at Mercy Medical Center
  - Cedar Rapids, Iowa, Forente stater, 52402
    - Saint Luke's Hospital
  - Cedar Rapids, Iowa, Forente stater, 52402
    - Physicians' Clinic of Iowa PC
  - Clive, Iowa, Forente stater, 50325
    - Mercy Cancer Center-West Lakes
  - Clive, Iowa, Forente stater, 50325
    - Medical Oncology and Hematology Associates-West Des Moines
  - Council Bluffs, Iowa, Forente stater, 51503
    - Alegent Health Mercy Hospital
  - Council Bluffs, Iowa, Forente stater, 51503
    - Heartland Oncology and Hematology LLP
  - Creston, Iowa, Forente stater, 50801
    - Greater Regional Medical Center
  - Davenport, Iowa, Forente stater, 52803
    - Genesis Medical Center - East Campus
  - Des Moines, Iowa, Forente stater, 50309
    - Iowa Methodist Medical Center
  - Des Moines, Iowa, Forente stater, 50314
    - Mercy Medical Center - Des Moines
  - Des Moines, Iowa, Forente stater, 50309
    - Medical Oncology and Hematology Associates-Des Moines
  - Des Moines, Iowa, Forente stater, 50314
    - Mission Cancer and Blood - Laurel
  - Des Moines, Iowa, Forente stater, 50316
    - Iowa Lutheran Hospital
  - Fairfield, Iowa, Forente stater, 52556
    - JCHC McCreery Cancer Center
  - Fort Dodge, Iowa, Forente stater, 50501
    - McFarland Clinic - Trinity Cancer Center
  - Jefferson, Iowa, Forente stater, 50129
    - McFarland Clinic - Jefferson
  - Marshalltown, Iowa, Forente stater, 50158
    - McFarland Clinic - Marshalltown
  - Mason City, Iowa, Forente stater, 50401
    - Mercy Medical Center - North Iowa
  - Ottumwa, Iowa, Forente stater, 52501
    - Ottumwa Regional Health Center
  - Sioux City, Iowa, Forente stater, 51101
    - Siouxland Regional Cancer Center
  - Sioux City, Iowa, Forente stater, 51102
    - Mercy Medical Center-Sioux City
  - Sioux City, Iowa, Forente stater, 51104
    - Saint Luke's Regional Medical Center
  - Waterloo, Iowa, Forente stater, 50702
    - MercyOne Waterloo Cancer Center
  - West Des Moines, Iowa, Forente stater, 50266-7700
    - Methodist West Hospital
  - West Des Moines, Iowa, Forente stater, 50266
    - Mercy Medical Center-West Lakes
- Kansas
  - Chanute, Kansas, Forente stater, 66720
    - Cancer Center of Kansas - Chanute
  - Dodge City, Kansas, Forente stater, 67801
    - Cancer Center of Kansas - Dodge City
  - El Dorado, Kansas, Forente stater, 67042
    - Cancer Center of Kansas - El Dorado
  - Emporia, Kansas, Forente stater, 66801
    - Newman Regional Health
  - Fort Scott, Kansas, Forente stater, 66701
    - Cancer Center of Kansas - Fort Scott
  - Garden City, Kansas, Forente stater, 67846
    - Saint Catherine Hospital
  - Great Bend, Kansas, Forente stater, 67530
    - Saint Rose Ambulatory and Surgery Center
  - Hays, Kansas, Forente stater, 67601
    - HaysMed University of Kansas Health System
  - Hutchinson, Kansas, Forente stater, 67502
    - Hutchinson Regional Medical Center
  - Independence, Kansas, Forente stater, 67301
    - Cancer Center of Kansas-Independence
  - Kansas City, Kansas, Forente stater, 66160
    - University of Kansas Cancer Center
  - Kansas City, Kansas, Forente stater, 66112
    - University of Kansas Cancer Center-West
  - Kansas City, Kansas, Forente stater, 66112
    - Providence Medical Center
  - Kingman, Kansas, Forente stater, 67068
    - Cancer Center of Kansas-Kingman
  - Lawrence, Kansas, Forente stater, 66044
    - Lawrence Memorial Hospital
  - Lenexa, Kansas, Forente stater, 66219
    - Kansas Institute of Medicine Cancer and Blood Center
  - Lenexa, Kansas, Forente stater, 66219
    - Minimally Invasive Surgery Hospital
  - Liberal, Kansas, Forente stater, 67905
    - Cancer Center of Kansas-Liberal
  - Manhattan, Kansas, Forente stater, 66502
    - Cancer Center of Kansas-Manhattan
  - McPherson, Kansas, Forente stater, 67460
    - Cancer Center of Kansas - McPherson
  - Newton, Kansas, Forente stater, 67114
    - Cancer Center of Kansas - Newton
  - Olathe, Kansas, Forente stater, 66061
    - Olathe Health Cancer Center
  - Overland Park, Kansas, Forente stater, 66210
    - University of Kansas Cancer Center-Overland Park
  - Overland Park, Kansas, Forente stater, 66209
    - Menorah Medical Center
  - Overland Park, Kansas, Forente stater, 66213
    - Saint Luke's South Hospital
  - Parsons, Kansas, Forente stater, 67357
    - Cancer Center of Kansas - Parsons
  - Pittsburg, Kansas, Forente stater, 66762
    - Ascension Via Christi - Pittsburg
  - Prairie Village, Kansas, Forente stater, 66208
    - Kansas City NCI Community Oncology Research Program
  - Pratt, Kansas, Forente stater, 67124
    - Cancer Center of Kansas - Pratt
  - Salina, Kansas, Forente stater, 67401
    - Salina Regional Health Center
  - Salina, Kansas, Forente stater, 67401
    - Cancer Center of Kansas - Salina
  - Topeka, Kansas, Forente stater, 66606
    - University of Kansas Health System Saint Francis Campus
  - Topeka, Kansas, Forente stater, 66606
    - Cotton O'Neil Cancer Center / Stormont Vail Health
  - Wellington, Kansas, Forente stater, 67152
    - Cancer Center of Kansas - Wellington
  - Wichita, Kansas, Forente stater, 67214
    - Ascension Via Christi Hospitals Wichita
  - Wichita, Kansas, Forente stater, 67208
    - Cancer Center of Kansas-Wichita Medical Arts Tower
  - Wichita, Kansas, Forente stater, 67214
    - Cancer Center of Kansas - Wichita
  - Wichita, Kansas, Forente stater, 67208
    - Associates In Womens Health
  - Wichita, Kansas, Forente stater, 67214
    - Wichita NCI Community Oncology Research Program
  - Wichita, Kansas, Forente stater, 67214
    - Wesley Medical Center
  - Winfield, Kansas, Forente stater, 67156
    - Cancer Center of Kansas - Winfield
- Kentucky
  - Ashland, Kentucky, Forente stater, 41101
    - King's Daughter's Medical Center
  - Bardstown, Kentucky, Forente stater, 40004
    - Flaget Memorial Hospital
  - Corbin, Kentucky, Forente stater, 40701
    - Baptist Health Corbin
  - Corbin, Kentucky, Forente stater, 40701
    - Commonwealth Cancer Center-Corbin
  - Crestview Hills, Kentucky, Forente stater, 41017
    - Oncology Hematology Care Inc-Crestview
  - Edgewood, Kentucky, Forente stater, 41017
    - Saint Elizabeth Healthcare Edgewood
  - Elizabethtown, Kentucky, Forente stater, 42701
    - Baptist Health Hardin
  - Fort Thomas, Kentucky, Forente stater, 41075
    - Saint Elizabeth Fort Thomas
  - Lexington, Kentucky, Forente stater, 40536
    - University of Kentucky/Markey Cancer Center
  - Lexington, Kentucky, Forente stater, 40504
    - Saint Joseph Radiation Oncology Resource Center
  - Lexington, Kentucky, Forente stater, 40509
    - Saint Joseph Hospital East
  - Lexington, Kentucky, Forente stater, 40503
    - Baptist Health Lexington
  - London, Kentucky, Forente stater, 40741
    - Saint Joseph London
  - Louisville, Kentucky, Forente stater, 40202
    - The James Graham Brown Cancer Center at University of Louisville
  - Louisville, Kentucky, Forente stater, 40202
    - Jewish Hospital
  - Louisville, Kentucky, Forente stater, 40245
    - UofL Health Medical Center Northeast
  - Louisville, Kentucky, Forente stater, 40215
    - Saints Mary and Elizabeth Hospital
  - Madisonville, Kentucky, Forente stater, 42431
    - Baptist Health Madisonville/Merle Mahr Cancer Center
  - Owensboro, Kentucky, Forente stater, 42303
    - Owensboro Health Mitchell Memorial Cancer Center
  - Paducah, Kentucky, Forente stater, 42003
    - Baptist Health Paducah
  - Shepherdsville, Kentucky, Forente stater, 40165
    - Jewish Hospital Medical Center South
- Louisiana
  - Alexandria, Louisiana, Forente stater, 71301
    - Christus Saint Frances Cabrini Hospital
  - Baton Rouge, Louisiana, Forente stater, 70805
    - LSU Health Baton Rouge-North Clinic
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Louisiana Hematology Oncology Associates LLC
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Mary Bird Perkins Cancer Center
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Our Lady of the Lake Physicians Group - Medical Oncology
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Ochsner Health Center-Summa
  - Baton Rouge, Louisiana, Forente stater, 70806
    - Baton Rouge General Medical Center
  - Baton Rouge, Louisiana, Forente stater, 70809
    - Hematology/Oncology Clinic PLLC
  - Covington, Louisiana, Forente stater, 70433
    - Mary Bird Perkins Cancer Center - Covington
  - Covington, Louisiana, Forente stater, 70433
    - Ochsner Health Center-Covington
  - Houma, Louisiana, Forente stater, 70360
    - Mary Bird Perkins Cancer Center - Houma
  - Kenner, Louisiana, Forente stater, 70065
    - Ochsner Medical Center Kenner
  - Marrero, Louisiana, Forente stater, 70072
    - West Jefferson Medical Center
  - Metairie, Louisiana, Forente stater, 70006
    - East Jefferson General Hospital
  - Metairie, Louisiana, Forente stater, 70006
    - Robert Veith MD LLC
  - Monroe, Louisiana, Forente stater, 71202
    - Ochsner LSU Health Monroe Medical Center
  - New Orleans, Louisiana, Forente stater, 70112
    - Tulane University School of Medicine
  - New Orleans, Louisiana, Forente stater, 70121
    - Ochsner Medical Center Jefferson
  - New Orleans, Louisiana, Forente stater, 70112
    - University Medical Center New Orleans
  - New Orleans, Louisiana, Forente stater, 70112
    - Louisiana State University Health Science Center
  - New Orleans, Louisiana, Forente stater, 70115
    - Ochsner Baptist Medical Center
  - Shreveport, Louisiana, Forente stater, 71103
    - LSU Health Sciences Center at Shreveport
  - Shreveport, Louisiana, Forente stater, 71105
    - Highland Clinic
- Maine
  - Augusta, Maine, Forente stater, 04330
    - Harold Alfond Center for Cancer Care
  - Bangor, Maine, Forente stater, 04401
    - Eastern Maine Medical Center
  - Brewer, Maine, Forente stater, 04412
    - Lafayette Family Cancer Center-EMMC
  - Portland, Maine, Forente stater, 04101
    - Mercy Hospital
  - Rockport, Maine, Forente stater, 04856
    - Penobscot Bay Medical Center
  - Scarborough, Maine, Forente stater, 04074
    - Maine Center for Cancer Medicine-Scarborough
- Maryland
  - Baltimore, Maryland, Forente stater, 21287
    - Johns Hopkins University/Sidney Kimmel Cancer Center
  - Baltimore, Maryland, Forente stater, 21215
    - Sinai Hospital of Baltimore
  - Baltimore, Maryland, Forente stater, 21204
    - Greater Baltimore Medical Center
  - Baltimore, Maryland, Forente stater, 21202
    - Mercy Medical Center
  - Baltimore, Maryland, Forente stater, 21218
    - MedStar Union Memorial Hospital
  - Baltimore, Maryland, Forente stater, 21244
    - Kaiser Permanente-Woodlawn Medical Center
  - Baltimore, Maryland, Forente stater, 21239
    - MedStar Good Samaritan Hospital
  - Bethesda, Maryland, Forente stater, 20889-5600
    - Walter Reed National Military Medical Center
  - Bethesda, Maryland, Forente stater, 20814
    - Suburban Hospital
  - Easton, Maryland, Forente stater, 21601
    - University of Maryland Shore Medical Center at Easton
  - Elkton, Maryland, Forente stater, 21921
    - Christiana Care - Union Hospital
  - Frederick, Maryland, Forente stater, 21701
    - Frederick Memorial Hospital
  - Gaithersburg, Maryland, Forente stater, 20879
    - Kaiser Permanente-Gaithersburg Medical Center
  - Kensington, Maryland, Forente stater, 20895
    - Kaiser Permanente - Kensington Medical Center
  - Largo, Maryland, Forente stater, 20774
    - Kaiser Permanente - Largo Medical Center
  - Olney, Maryland, Forente stater, 20832
    - MedStar Montgomery Medical Center
  - Randallstown, Maryland, Forente stater, 21133
    - Northwest Hospital Center
  - Salisbury, Maryland, Forente stater, 21801
    - TidalHealth Peninsula Regional
  - Westminster, Maryland, Forente stater, 21157
    - William E Kahlert Regional Cancer Center/Sinai Hospital
- Massachusetts
  - Attleboro, Massachusetts, Forente stater, 02703
    - Sturdy Memorial Hospital
  - Beverly, Massachusetts, Forente stater, 01915
    - Beverly Hospital
  - Boston, Massachusetts, Forente stater, 02215
    - Beth Israel Deaconess Medical Center
  - Boston, Massachusetts, Forente stater, 02215
    - Dana-Farber Cancer Institute
  - Boston, Massachusetts, Forente stater, 02115
    - Brigham and Women's Hospital
  - Brighton, Massachusetts, Forente stater, 02135
    - Steward Saint Elizabeth's Medical Center
  - Burlington, Massachusetts, Forente stater, 01805
    - Lahey Hospital and Medical Center
  - Danvers, Massachusetts, Forente stater, 01923
    - Mass General/North Shore Cancer Center
  - Fall River, Massachusetts, Forente stater, 02721
    - Saint Anne's Hospital
  - Gloucester, Massachusetts, Forente stater, 01930
    - Addison Gilbert Hospital
  - Hyannis, Massachusetts, Forente stater, 02601
    - Cape Cod Hospital
  - Lowell, Massachusetts, Forente stater, 01854
    - Lowell General Hospital
  - Methuen, Massachusetts, Forente stater, 01844
    - Holy Family Hospital
  - Milford, Massachusetts, Forente stater, 01757
    - Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
  - Newton, Massachusetts, Forente stater, 02462
    - Newton-Wellesley Hospital
  - Pittsfield, Massachusetts, Forente stater, 01201
    - Berkshire Medical Center - Cancer Center
  - Plymouth, Massachusetts, Forente stater, 02360
    - Beth Israel Deaconess Hospital-Plymouth
  - Quincy, Massachusetts, Forente stater, 02169
    - Dana Farber Community Cancer Care-Quincy
  - South Weymouth, Massachusetts, Forente stater, 02190
    - Dana-Farber/Brigham and Women's Cancer Center at South Shore
  - Worcester, Massachusetts, Forente stater, 01655
    - UMass Memorial Medical Center - University Campus
- Michigan
  - Adrian, Michigan, Forente stater, 49221
    - Bixby Medical Center
  - Adrian, Michigan, Forente stater, 49221
    - Hickman Cancer Center
  - Ann Arbor, Michigan, Forente stater, 48109
    - University of Michigan Comprehensive Cancer Center
  - Ann Arbor, Michigan, Forente stater, 48106
    - Saint Joseph Mercy Hospital
  - Ann Arbor, Michigan, Forente stater, 48106
    - Michigan Cancer Research Consortium NCORP
  - Battle Creek, Michigan, Forente stater, 49017
    - Bronson Battle Creek
  - Bay City, Michigan, Forente stater, 48706
    - McLaren Cancer Institute-Bay City
  - Big Rapids, Michigan, Forente stater, 49307
    - Spectrum Health Big Rapids Hospital
  - Brighton, Michigan, Forente stater, 48114
    - Saint Joseph Mercy Brighton
  - Brighton, Michigan, Forente stater, 48114
    - Trinity Health IHA Medical Group Hematology Oncology - Brighton
  - Brownstown, Michigan, Forente stater, 48183
    - Henry Ford Cancer Institute-Downriver
  - Canton, Michigan, Forente stater, 48188
    - Saint Joseph Mercy Canton
  - Canton, Michigan, Forente stater, 48188
    - Trinity Health IHA Medical Group Hematology Oncology - Canton
  - Caro, Michigan, Forente stater, 48723
    - Caro Cancer Center
  - Chelsea, Michigan, Forente stater, 48118
    - Saint Joseph Mercy Chelsea
  - Chelsea, Michigan, Forente stater, 48118
    - Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
  - Clarkston, Michigan, Forente stater, 48346
    - McLaren Cancer Institute-Clarkston
  - Clarkston, Michigan, Forente stater, 48346
    - Hematology Oncology Consultants-Clarkston
  - Clarkston, Michigan, Forente stater, 48346
    - Newland Medical Associates-Clarkston
  - Clinton Township, Michigan, Forente stater, 48038
    - Henry Ford Macomb Hospital-Clinton Township
  - Commerce, Michigan, Forente stater, 48382
    - Huron Valley-Sinai Hospital
  - Dearborn, Michigan, Forente stater, 48124
    - Beaumont Hospital - Dearborn
  - Dearborn, Michigan, Forente stater, 48126
    - Henry Ford Medical Center-Fairlane
  - Detroit, Michigan, Forente stater, 48202
    - Henry Ford Hospital
  - Detroit, Michigan, Forente stater, 48201
    - Wayne State University/Karmanos Cancer Institute
  - Detroit, Michigan, Forente stater, 48236
    - Ascension Saint John Hospital
  - East China Township, Michigan, Forente stater, 48054
    - Great Lakes Cancer Management Specialists-Doctors Park
  - Escanaba, Michigan, Forente stater, 49829
    - Green Bay Oncology - Escanaba
  - Farmington Hills, Michigan, Forente stater, 48334
    - Weisberg Cancer Treatment Center
  - Farmington Hills, Michigan, Forente stater, 48336
    - Beaumont Hospital - Farmington Hills
  - Flint, Michigan, Forente stater, 48532
    - Genesys Regional Medical Center-West Flint Campus
  - Flint, Michigan, Forente stater, 48532
    - McLaren Cancer Institute-Flint
  - Flint, Michigan, Forente stater, 48532
    - Singh and Arora Hematology Oncology PC
  - Flint, Michigan, Forente stater, 48503
    - Hurley Medical Center
  - Flint, Michigan, Forente stater, 48503
    - Genesee Cancer and Blood Disease Treatment Center
  - Flint, Michigan, Forente stater, 48503
    - Genesee Hematology Oncology PC
  - Flint, Michigan, Forente stater, 48503
    - Genesys Hurley Cancer Institute
  - Grand Rapids, Michigan, Forente stater, 49503
    - Spectrum Health at Butterworth Campus
  - Grand Rapids, Michigan, Forente stater, 49503
    - Cancer Research Consortium of West Michigan NCORP
  - Grand Rapids, Michigan, Forente stater, 49503
    - Trinity Health Grand Rapids Hospital
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Academic Hematology Oncology Specialists
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
  - Grosse Pointe Woods, Michigan, Forente stater, 48236
    - Michigan Breast Specialists-Grosse Pointe Woods
  - Iron Mountain, Michigan, Forente stater, 49801
    - Green Bay Oncology - Iron Mountain
  - Jackson, Michigan, Forente stater, 49201
    - Allegiance Health
  - Kalamazoo, Michigan, Forente stater, 49007
    - West Michigan Cancer Center
  - Kalamazoo, Michigan, Forente stater, 49007
    - Bronson Methodist Hospital
  - Kalamazoo, Michigan, Forente stater, 49048
    - Borgess Medical Center
  - Lansing, Michigan, Forente stater, 48910
    - Karmanos Cancer Institute at McLaren Greater Lansing
  - Lansing, Michigan, Forente stater, 48912
    - University of Michigan Health - Sparrow Lansing
  - Lapeer, Michigan, Forente stater, 48446
    - McLaren Cancer Institute-Lapeer Region
  - Livonia, Michigan, Forente stater, 48154
    - Trinity Health Saint Mary Mercy Livonia Hospital
  - Livonia, Michigan, Forente stater, 48154
    - Hope Cancer Clinic
  - Macomb, Michigan, Forente stater, 48044
    - Great Lakes Cancer Management Specialists-Macomb Medical Campus
  - Macomb, Michigan, Forente stater, 48044
    - Michigan Breast Specialists-Macomb Township
  - Marlette, Michigan, Forente stater, 48453
    - Saint Mary's Oncology/Hematology Associates of Marlette
  - Marquette, Michigan, Forente stater, 49855
    - UP Health System Marquette
  - Midland, Michigan, Forente stater, 48670
    - MyMichigan Medical Center Midland
  - Monroe, Michigan, Forente stater, 48162
    - Mercy Memorial Hospital
  - Monroe, Michigan, Forente stater, 48162
    - Toledo Clinic Cancer Centers-Monroe
  - Monroe, Michigan, Forente stater, 48162
    - Monroe Cancer Center
  - Mount Clemens, Michigan, Forente stater, 48043
    - McLaren Cancer Institute-Macomb
  - Mount Pleasant, Michigan, Forente stater, 48858
    - McLaren Cancer Institute-Central Michigan
  - Muskegon, Michigan, Forente stater, 49444
    - Trinity Health Muskegon Hospital
  - Niles, Michigan, Forente stater, 49120
    - Corewell Health Lakeland Hospitals - Niles Hospital
  - Novi, Michigan, Forente stater, 48374
    - Ascension Providence Hospitals - Novi
  - Novi, Michigan, Forente stater, 48377
    - Henry Ford Medical Center-Columbus
  - Petoskey, Michigan, Forente stater, 49770
    - McLaren Cancer Institute-Northern Michigan
  - Pontiac, Michigan, Forente stater, 48341
    - Saint Joseph Mercy Oakland
  - Pontiac, Michigan, Forente stater, 48341
    - 21st Century Oncology-Pontiac
  - Pontiac, Michigan, Forente stater, 48341
    - Hope Cancer Center
  - Pontiac, Michigan, Forente stater, 48341
    - Newland Medical Associates-Pontiac
  - Port Huron, Michigan, Forente stater, 48060
    - Lake Huron Medical Center
  - Reed City, Michigan, Forente stater, 49677
    - Corewell Health Reed City Hospital
  - Rochester Hills, Michigan, Forente stater, 48309
    - Great Lakes Cancer Management Specialists-Rochester Hills
  - Royal Oak, Michigan, Forente stater, 48073
    - William Beaumont Hospital-Royal Oak
  - Saginaw, Michigan, Forente stater, 48601
    - Ascension Saint Mary's Hospital
  - Saginaw, Michigan, Forente stater, 48604
    - Oncology Hematology Associates of Saginaw Valley PC
  - Saint Joseph, Michigan, Forente stater, 49085
    - Lakeland Medical Center Saint Joseph
  - Saint Joseph, Michigan, Forente stater, 49085
    - Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
  - Southfield, Michigan, Forente stater, 48075
    - Ascension Providence Hospitals - Southfield
  - Sterling Heights, Michigan, Forente stater, 48312
    - Bhadresh Nayak MD PC-Sterling Heights
  - Tawas City, Michigan, Forente stater, 48764
    - Ascension Saint Joseph Hospital
  - Traverse City, Michigan, Forente stater, 49684
    - Munson Medical Center
  - Troy, Michigan, Forente stater, 48085
    - William Beaumont Hospital - Troy
  - Warren, Michigan, Forente stater, 48093
    - Saint John Macomb-Oakland Hospital
  - Warren, Michigan, Forente stater, 48088
    - Advanced Breast Care Center PLLC
  - Warren, Michigan, Forente stater, 48093
    - Great Lakes Cancer Management Specialists-Macomb Professional Building
  - Warren, Michigan, Forente stater, 48093
    - Macomb Hematology Oncology PC
  - Warren, Michigan, Forente stater, 48093
    - Michigan Breast Specialists-Warren
  - West Bloomfield, Michigan, Forente stater, 48322
    - Henry Ford West Bloomfield Hospital
  - West Branch, Michigan, Forente stater, 48661
    - Saint Mary's Oncology/Hematology Associates of West Branch
  - Wyoming, Michigan, Forente stater, 49519
    - University of Michigan Health - West
  - Ypsilanti, Michigan, Forente stater, 48197
    - Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
  - Ypsilanti, Michigan, Forente stater, 48106
    - Huron Gastroenterology PC
- Minnesota
  - Alexandria, Minnesota, Forente stater, 56308
    - Medini, Eitan MD (UIA Investigator)
  - Burnsville, Minnesota, Forente stater, 55337
    - Fairview Ridges Hospital
  - Coon Rapids, Minnesota, Forente stater, 55433
    - Mercy Hospital
  - Duluth, Minnesota, Forente stater, 55805
    - Saint Luke's Hospital of Duluth
  - Edina, Minnesota, Forente stater, 55435
    - Fairview Southdale Hospital
  - Fridley, Minnesota, Forente stater, 55432
    - Unity Hospital
  - Hutchinson, Minnesota, Forente stater, 55350
    - Hutchinson Area Health Care
  - Mankato, Minnesota, Forente stater, 56001
    - Mayo Clinic Health Systems-Mankato
  - Maple Grove, Minnesota, Forente stater, 55369
    - Fairview Clinics and Surgery Center Maple Grove
  - Maplewood, Minnesota, Forente stater, 55109
    - Saint John's Hospital - Healtheast
  - Maplewood, Minnesota, Forente stater, 55109
    - Minnesota Oncology Hematology PA-Maplewood
  - Minneapolis, Minnesota, Forente stater, 55415
    - Hennepin County Medical Center
  - Minneapolis, Minnesota, Forente stater, 55407
    - Abbott-Northwestern Hospital
  - Minneapolis, Minnesota, Forente stater, 55454
    - Health Partners Inc
  - New Ulm, Minnesota, Forente stater, 56073
    - New Ulm Medical Center
  - Robbinsdale, Minnesota, Forente stater, 55422
    - North Memorial Medical Health Center
  - Rochester, Minnesota, Forente stater, 55905
    - Mayo Clinic in Rochester
  - Saint Cloud, Minnesota, Forente stater, 56303
    - Coborn Cancer Center at Saint Cloud Hospital
  - Saint Cloud, Minnesota, Forente stater, 56303
    - Saint Cloud Hospital
  - Saint Louis Park, Minnesota, Forente stater, 55416
    - Park Nicollet Clinic - Saint Louis Park
  - Saint Louis Park, Minnesota, Forente stater, 55416
    - Metro Minnesota Community Oncology Research Consortium
  - Saint Paul, Minnesota, Forente stater, 55101
    - Regions Hospital
  - Saint Paul, Minnesota, Forente stater, 55102
    - United Hospital
  - Shakopee, Minnesota, Forente stater, 55379
    - Saint Francis Regional Medical Center
  - Stillwater, Minnesota, Forente stater, 55082
    - Lakeview Hospital
  - Waconia, Minnesota, Forente stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forente stater, 56201
    - Rice Memorial Hospital
  - Woodbury, Minnesota, Forente stater, 55125
    - Minnesota Oncology Hematology PA-Woodbury
  - Wyoming, Minnesota, Forente stater, 55092
    - Fairview Lakes Medical Center
- Mississippi
  - Gulfport, Mississippi, Forente stater, 39502
    - Gulfport Memorial Hospital
  - Hattiesburg, Mississippi, Forente stater, 39401
    - Hattiesburg Clinic - Hematology/Oncology Clinic
  - Hattiesburg, Mississippi, Forente stater, 39404
    - Forrest General Hospital / Cancer Center
  - Jackson, Mississippi, Forente stater, 39216
    - University of Mississippi Medical Center
  - Pascagoula, Mississippi, Forente stater, 39581
    - Singing River Hospital
- Missouri
  - Bolivar, Missouri, Forente stater, 65613
    - Central Care Cancer Center - Bolivar
  - Bonne Terre, Missouri, Forente stater, 63628
    - Parkland Health Center-Bonne Terre
  - Branson, Missouri, Forente stater, 65616
    - Cox Cancer Center Branson
  - Cape Girardeau, Missouri, Forente stater, 63703
    - Saint Francis Medical Center
  - Cape Girardeau, Missouri, Forente stater, 63703
    - Southeast Cancer Center
  - Chesterfield, Missouri, Forente stater, 63017
    - Saint Luke's Hospital
  - Columbia, Missouri, Forente stater, 65212
    - MU Health - University Hospital/Ellis Fischel Cancer Center
  - Creve Coeur, Missouri, Forente stater, 63141
    - Siteman Cancer Center at West County Hospital
  - Independence, Missouri, Forente stater, 64057
    - Centerpoint Medical Center LLC
  - Jefferson City, Missouri, Forente stater, 65109
    - Capital Region Southwest Campus
  - Joplin, Missouri, Forente stater, 64804
    - Freeman Health System
  - Joplin, Missouri, Forente stater, 64804
    - Mercy Hospital Joplin
  - Kansas City, Missouri, Forente stater, 64154
    - University of Kansas Cancer Center - North
  - Kansas City, Missouri, Forente stater, 64116
    - North Kansas City Hospital
  - Kansas City, Missouri, Forente stater, 64131
    - The University of Kansas Cancer Center-South
  - Kansas City, Missouri, Forente stater, 64111
    - Saint Luke's Hospital of Kansas City
  - Kansas City, Missouri, Forente stater, 64132
    - Research Medical Center
  - Kansas City, Missouri, Forente stater, 64108
    - Truman Medical Centers
  - Kansas City, Missouri, Forente stater, 64118
    - Heartland Hematology and Oncology Associates Incorporated
  - Kansas City, Missouri, Forente stater, 64114
    - Saint Joseph Health Center
  - Lee's Summit, Missouri, Forente stater, 64064
    - University of Kansas Cancer Center - Lee's Summit
  - Lee's Summit, Missouri, Forente stater, 64086
    - Saint Luke's East - Lee's Summit
  - Liberty, Missouri, Forente stater, 64068
    - Liberty Radiation Oncology Center
  - Rolla, Missouri, Forente stater, 65401
    - Delbert Day Cancer Institute at PCRMC
  - Rolla, Missouri, Forente stater, 65401
    - Mercy Clinic-Rolla-Cancer and Hematology
  - Saint Joseph, Missouri, Forente stater, 64506
    - Heartland Regional Medical Center
  - Saint Joseph, Missouri, Forente stater, 64507
    - Saint Joseph Oncology Inc
  - Saint Louis, Missouri, Forente stater, 63110
    - Washington University School of Medicine
  - Saint Louis, Missouri, Forente stater, 63131
    - Missouri Baptist Medical Center
  - Saint Louis, Missouri, Forente stater, 63141
    - Mercy Hospital Saint Louis
  - Saint Louis, Missouri, Forente stater, 63136
    - Siteman Cancer Center at Christian Hospital
  - Saint Louis, Missouri, Forente stater, 63109
    - Saint Louis Cancer and Breast Institute-South City
  - Saint Louis, Missouri, Forente stater, 63141
    - Saint Louis-Cape Girardeau CCOP
  - Saint Louis, Missouri, Forente stater, 63104
    - SSM Health Saint Louis University Hospital
  - Saint Louis, Missouri, Forente stater, 63141
    - Comprehensive Cancer Care PC
  - Saint Peters, Missouri, Forente stater, 63376
    - Siteman Cancer Center at Saint Peters Hospital
  - Sainte Genevieve, Missouri, Forente stater, 63670
    - Sainte Genevieve County Memorial Hospital
  - Springfield, Missouri, Forente stater, 65804
    - Cancer Research for the Ozarks NCORP
  - Springfield, Missouri, Forente stater, 65807
    - CoxHealth South Hospital
  - Springfield, Missouri, Forente stater, 65804
    - Mercy Hospital Springfield
  - Sullivan, Missouri, Forente stater, 63080
    - Missouri Baptist Sullivan Hospital
  - Sunset Hills, Missouri, Forente stater, 63127
    - BJC Outpatient Center at Sunset Hills
- Montana
  - Anaconda, Montana, Forente stater, 59711
    - Community Hospital of Anaconda
  - Billings, Montana, Forente stater, 59101
    - Billings Clinic Cancer Center
  - Billings, Montana, Forente stater, 59101
    - Saint Vincent Healthcare
  - Billings, Montana, Forente stater, 59102
    - Montana Cancer Consortium NCORP
  - Billings, Montana, Forente stater, 59102
    - Saint Vincent Frontier Cancer Center
  - Bozeman, Montana, Forente stater, 59715
    - Bozeman Deaconess Hospital
  - Butte, Montana, Forente stater, 59701
    - Saint James Community Hospital and Cancer Treatment Center
  - Great Falls, Montana, Forente stater, 59405
    - Great Falls Clinic
  - Great Falls, Montana, Forente stater, 59405
    - Benefis Healthcare- Sletten Cancer Institute
  - Havre, Montana, Forente stater, 59501
    - Northern Montana Hospital
  - Helena, Montana, Forente stater, 59601
    - Saint Peter's Community Hospital
  - Kalispell, Montana, Forente stater, 59901
    - Kalispell Regional Medical Center
  - Kalispell, Montana, Forente stater, 59901
    - Glacier Oncology PLLC
  - Kalispell, Montana, Forente stater, 59901
    - Kalispell Medical Oncology
  - Missoula, Montana, Forente stater, 59804
    - Community Medical Hospital
  - Missoula, Montana, Forente stater, 59802
    - Saint Patrick Hospital - Community Hospital
  - Missoula, Montana, Forente stater, 59802
    - Montana Cancer Specialists
- Nebraska
  - Grand Island, Nebraska, Forente stater, 68803
    - CHI Health Saint Francis
  - Kearney, Nebraska, Forente stater, 68847
    - CHI Health Good Samaritan
  - Kearney, Nebraska, Forente stater, 68845
    - Heartland Hematology and Oncology
  - Lincoln, Nebraska, Forente stater, 68506
    - Nebraska Hematology and Oncology
  - Lincoln, Nebraska, Forente stater, 68510
    - Nebraska Cancer Research Center
  - Lincoln, Nebraska, Forente stater, 68516
    - Southeast Nebraska Cancer Center - 68th Street Place
  - Lincoln, Nebraska, Forente stater, 68510
    - Saint Elizabeth Regional Medical Center
  - Norfolk, Nebraska, Forente stater, 68701
    - Faith Regional Health Services Carson Cancer Center
  - North Platte, Nebraska, Forente stater, 69101
    - Great Plains Health Callahan Cancer Center
  - Omaha, Nebraska, Forente stater, 68114
    - Nebraska Methodist Hospital
  - Omaha, Nebraska, Forente stater, 68198
    - University of Nebraska Medical Center
  - Omaha, Nebraska, Forente stater, 68124
    - Alegent Health Bergan Mercy Medical Center
  - Omaha, Nebraska, Forente stater, 68122
    - Alegent Health Immanuel Medical Center
  - Omaha, Nebraska, Forente stater, 68130
    - Alegent Health Lakeside Hospital
  - Omaha, Nebraska, Forente stater, 68131
    - Creighton University Medical Center
  - Omaha, Nebraska, Forente stater, 68106
    - Missouri Valley Cancer Consortium
  - Omaha, Nebraska, Forente stater, 68124
    - Nebraska Cancer Specialists - Omaha
  - Omaha, Nebraska, Forente stater, 68130
    - Oncology Hematology West PC
  - Omaha, Nebraska, Forente stater, 68130
    - Urology Cancer Center PC
  - Omaha, Nebraska, Forente stater, 68122
    - Hematology and Oncology Consultants PC
  - Papillion, Nebraska, Forente stater, 68046
    - Midlands Community Hospital
  - Scottsbluff, Nebraska, Forente stater, 69361
    - Regional West Medical Center Cancer Center
- Nevada
  - Henderson, Nevada, Forente stater, 89052
    - Comprehensive Cancer Centers of Nevada - Henderson
  - Henderson, Nevada, Forente stater, 89052
    - OptumCare Cancer Care at Seven Hills
  - Henderson, Nevada, Forente stater, 89052
    - Cancer and Blood Specialists-Henderson
  - Henderson, Nevada, Forente stater, 89052
    - Las Vegas Cancer Center-Henderson
  - Henderson, Nevada, Forente stater, 89074
    - Comprehensive Cancer Centers of Nevada-Southeast Henderson
  - Henderson, Nevada, Forente stater, 89074
    - GenesisCare USA - Henderson
  - Henderson, Nevada, Forente stater, 89052
    - Comprehensive Cancer Centers of Nevada-Horizon Ridge
  - Las Vegas, Nevada, Forente stater, 89144
    - Summerlin Hospital Medical Center
  - Las Vegas, Nevada, Forente stater, 89102
    - OptumCare Cancer Care at Charleston
  - Las Vegas, Nevada, Forente stater, 89106
    - Radiation Oncology Centers of Nevada Central
  - Las Vegas, Nevada, Forente stater, 89109
    - GenesisCare USA - Las Vegas
  - Las Vegas, Nevada, Forente stater, 89119
    - Radiation Oncology Centers of Nevada Southeast
  - Las Vegas, Nevada, Forente stater, 89128
    - Comprehensive Cancer Centers of Nevada - Northwest
  - Las Vegas, Nevada, Forente stater, 89128
    - OptumCare Cancer Care at MountainView
  - Las Vegas, Nevada, Forente stater, 89135
    - Alliance for Childhood Diseases/Cure 4 the Kids Foundation
  - Las Vegas, Nevada, Forente stater, 89144
    - Comprehensive Cancer Centers of Nevada-Summerlin
  - Las Vegas, Nevada, Forente stater, 89148
    - Comprehensive Cancer Centers of Nevada
  - Las Vegas, Nevada, Forente stater, 89148
    - OptumCare Cancer Care at Fort Apache
  - Las Vegas, Nevada, Forente stater, 89169
    - Comprehensive Cancer Centers of Nevada - Central Valley
  - Las Vegas, Nevada, Forente stater, 89102
    - University Medical Center of Southern Nevada
  - Las Vegas, Nevada, Forente stater, 89106
    - Cancer and Blood Specialists-Shadow
  - Las Vegas, Nevada, Forente stater, 89109
    - HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
  - Las Vegas, Nevada, Forente stater, 89113
    - HealthCare Partners Medical Group Oncology/Hematology-San Martin
  - Las Vegas, Nevada, Forente stater, 89121
    - Cancer Therapy and Integrative Medicine
  - Las Vegas, Nevada, Forente stater, 89128
    - Cancer and Blood Specialists-Tenaya
  - Las Vegas, Nevada, Forente stater, 89128
    - GenesisCare USA - Vegas Tenaya
  - Las Vegas, Nevada, Forente stater, 89128
    - HealthCare Partners Medical Group Oncology/Hematology-Tenaya
  - Las Vegas, Nevada, Forente stater, 89148-2405
    - Las Vegas Cancer Center-Medical Center
  - Las Vegas, Nevada, Forente stater, 89148
    - GenesisCare USA - Fort Apache
  - Las Vegas, Nevada, Forente stater, 89149
    - HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
  - Las Vegas, Nevada, Forente stater, 89169
    - Nevada Cancer Research Foundation NCORP
  - Las Vegas, Nevada, Forente stater, 89128
    - Ann M Wierman MD LTD
  - Las Vegas, Nevada, Forente stater, 89102
    - Desert West Surgery
  - Pahrump, Nevada, Forente stater, 89048
    - Hope Cancer Care of Nevada-Pahrump
  - Reno, Nevada, Forente stater, 89502
    - Renown Regional Medical Center
  - Reno, Nevada, Forente stater, 89503
    - Saint Mary's Regional Medical Center
  - Reno, Nevada, Forente stater, 89509
    - Radiation Oncology Associates
- New Hampshire
  - Derry, New Hampshire, Forente stater, 03038
    - Parkland Medical Center
  - Dover, New Hampshire, Forente stater, 03820
    - Wentworth-Douglass Hospital
  - Keene, New Hampshire, Forente stater, 03431
    - Cheshire Medical Center-Dartmouth-Hitchcock Keene
  - Lebanon, New Hampshire, Forente stater, 03756
    - Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
  - Londonderry, New Hampshire, Forente stater, 03053
    - The Dana-Farber Cancer Institute at Londonderry
  - Manchester, New Hampshire, Forente stater, 03102
    - Norris Cotton Cancer Center-Manchester
  - Nashua, New Hampshire, Forente stater, 03060
    - Foundation Medical Partners
  - Nashua, New Hampshire, Forente stater, 03063
    - Dartmouth Cancer Center - Nashua
  - Portsmouth, New Hampshire, Forente stater, 03802
    - Portsmouth Regional Hospital
- New Jersey
  - Basking Ridge, New Jersey, Forente stater, 07920
    - Memorial Sloan Kettering Basking Ridge
  - Camden, New Jersey, Forente stater, 08103
    - Cooper Hospital University Medical Center
  - Cape May Court House, New Jersey, Forente stater, 08210
    - AtlantiCare Health Park-Cape May Court House
  - Egg Harbor Township, New Jersey, Forente stater, 08234
    - AtlantiCare Surgery Center
  - Englewood, New Jersey, Forente stater, 07631
    - Englewood Hospital and Medical Center
  - Hackensack, New Jersey, Forente stater, 07601
    - Hackensack University Medical Center
  - Hamilton, New Jersey, Forente stater, 08690
    - The Cancer Institute of New Jersey Hamilton
  - Livingston, New Jersey, Forente stater, 07039
    - Saint Barnabas Medical Center
  - Long Branch, New Jersey, Forente stater, 07740
    - Monmouth Medical Center
  - Morristown, New Jersey, Forente stater, 07960
    - Morristown Medical Center
  - Mount Holly, New Jersey, Forente stater, 08060
    - Virtua Memorial
  - Mullica Hill, New Jersey, Forente stater, 08062
    - Inspira Medical Center Mullica Hill
  - New Brunswick, New Jersey, Forente stater, 08903
    - Rutgers Cancer Institute of New Jersey
  - New Brunswick, New Jersey, Forente stater, 08901
    - Saint Peter's University Hospital
  - New Brunswick, New Jersey, Forente stater, 08903
    - Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital
  - Newark, New Jersey, Forente stater, 07101
    - Rutgers New Jersey Medical School
  - Newark, New Jersey, Forente stater, 07112
    - Newark Beth Israel Medical Center
  - Paramus, New Jersey, Forente stater, 07652
    - The Valley Hospital-Luckow Pavilion
  - Paterson, New Jersey, Forente stater, 07503
    - Saint Joseph's Regional Medical Center
  - Pennington, New Jersey, Forente stater, 08534
    - Capital Health Medical Center-Hopewell
  - Pomona, New Jersey, Forente stater, 08240
    - AtlantiCare Regional Medical Center -Main Campus
  - Ridgewood, New Jersey, Forente stater, 07450
    - Valley Hospital
  - Ridgewood, New Jersey, Forente stater, 07450
    - Neurosurgeons of New Jersey-Ridgewood
  - Sewell, New Jersey, Forente stater, 08080
    - Sidney Kimmel Cancer Center Washington Township
  - Somerville, New Jersey, Forente stater, 08876
    - Robert Wood Johnson University Hospital Somerset
  - Sparta, New Jersey, Forente stater, 07871
    - Sparta Cancer Treatment Center
  - Summit, New Jersey, Forente stater, 07902
    - Overlook Hospital
  - Vineland, New Jersey, Forente stater, 08360
    - Inspira Medical Center Vineland
  - Voorhees, New Jersey, Forente stater, 08043
    - Virtua Voorhees
  - Westwood, New Jersey, Forente stater, 07675
    - Valley Health System-Hematology/Oncology
- New Mexico
  - Albuquerque, New Mexico, Forente stater, 87102
    - University of New Mexico Cancer Center
  - Albuquerque, New Mexico, Forente stater, 87102
    - Lovelace Medical Center-Saint Joseph Square
  - Albuquerque, New Mexico, Forente stater, 87110
    - Presbyterian Kaseman Hospital
  - Las Cruces, New Mexico, Forente stater, 88011
    - Memorial Medical Center - Las Cruces
  - Santa Fe, New Mexico, Forente stater, 87505
    - Christus Saint Vincent Regional Cancer Center
- New York
  - Bronx, New York, Forente stater, 10467
    - Montefiore Medical Center - Moses Campus
  - Bronx, New York, Forente stater, 10461
    - Montefiore Medical Center-Weiler Hospital
  - Bronx, New York, Forente stater, 10451
    - Lincoln Medical and Mental Health Center
  - Brooklyn, New York, Forente stater, 11219
    - Maimonides Medical Center
  - Buffalo, New York, Forente stater, 14263
    - Roswell Park Cancer Institute
  - Commack, New York, Forente stater, 11725
    - Memorial Sloan Kettering Commack
  - Cooperstown, New York, Forente stater, 13326
    - Mary Imogene Bassett Hospital
  - Elmhurst, New York, Forente stater, 11373
    - Elmhurst Hospital Center
  - Elmira, New York, Forente stater, 14905
    - Arnot Ogden Medical Center/Falck Cancer Center
  - Glens Falls, New York, Forente stater, 12801
    - Glens Falls Hospital
  - Harrison, New York, Forente stater, 10604
    - Memorial Sloan Kettering Westchester
  - Jamaica, New York, Forente stater, 11432
    - Queens Hospital Center
  - Lake Success, New York, Forente stater, 11042
    - Northwell Health NCORP
  - Lake Success, New York, Forente stater, 11042
    - Northwell Health/Center for Advanced Medicine
  - Manhasset, New York, Forente stater, 11030
    - North Shore University Hospital
  - Middletown, New York, Forente stater, 10940
    - Garnet Health Medical Center
  - Mineola, New York, Forente stater, 11501
    - NYU Winthrop Hospital
  - New Hyde Park, New York, Forente stater, 11040
    - Long Island Jewish Medical Center
  - New York, New York, Forente stater, 10065
    - Memorial Sloan Kettering Cancer Center
  - New York, New York, Forente stater, 10019
    - Mount Sinai West
  - New York, New York, Forente stater, 10032
    - NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
  - New York, New York, Forente stater, 10065
    - NYP/Weill Cornell Medical Center
  - New York, New York, Forente stater, 10016
    - Laura and Isaac Perlmutter Cancer Center at NYU Langone
  - New York, New York, Forente stater, 10003
    - Mount Sinai Union Square
  - Nyack, New York, Forente stater, 10960
    - Nyack Hospital
  - Poughkeepsie, New York, Forente stater, 12601
    - MidHudson Regional Hospital of Westchester Medical Center
  - Rochester, New York, Forente stater, 14642
    - University of Rochester
  - Rochester, New York, Forente stater, 14621
    - Rochester General Hospital
  - Sleepy Hollow, New York, Forente stater, 10591
    - Memorial Sloan Kettering Sleepy Hollow
  - Staten Island, New York, Forente stater, 10305
    - Staten Island University Hospital
  - Stony Brook, New York, Forente stater, 11794
    - Stony Brook University Medical Center
  - Syracuse, New York, Forente stater, 13210
    - State University of New York Upstate Medical University
  - Uniondale, New York, Forente stater, 11553
    - Memorial Sloan Kettering Nassau
  - Utica, New York, Forente stater, 13502
    - Faxton-Saint Luke's Healthcare
  - White Plains, New York, Forente stater, 10601
    - Dickstein Cancer Treatment Center
- North Carolina
  - Albemarle, North Carolina, Forente stater, 28002
    - Atrium Health Stanly/LCI-Albemarle
  - Asheboro, North Carolina, Forente stater, 27203
    - Randolph Hospital
  - Asheville, North Carolina, Forente stater, 28801
    - Mission Hospital
  - Asheville, North Carolina, Forente stater, 28816
    - Hope Women's Cancer Centers-Asheville
  - Asheville, North Carolina, Forente stater, 28806
    - Messino Cancer Centers
  - Asheville, North Carolina, Forente stater, 28801
    - Mountain Radiation Oncology PA
  - Asheville, North Carolina, Forente stater, 28803
    - AdventHealth Infusion Center Asheville
  - Belmont, North Carolina, Forente stater, 28012
    - Gaston Hematology and Oncology Associates-Belmont
  - Brevard, North Carolina, Forente stater, 28712
    - Transylvania Regional Hospital
  - Burlington, North Carolina, Forente stater, 27215
    - Cone Health Cancer Center at Alamance Regional
  - Cary, North Carolina, Forente stater, 27518
    - Waverly Hematology Oncology
  - Charlotte, North Carolina, Forente stater, 28203
    - Carolinas Medical Center/Levine Cancer Institute
  - Charlotte, North Carolina, Forente stater, 28204
    - Novant Health Presbyterian Medical Center
  - Charlotte, North Carolina, Forente stater, 28210
    - Atrium Health Pineville/LCI-Pineville
  - Charlotte, North Carolina, Forente stater, 28262
    - Atrium Health University City/LCI-University
  - Charlotte, North Carolina, Forente stater, 28207
    - Oncology Specialists of Charlotte
  - Charlotte, North Carolina, Forente stater, 28262
    - Southern Oncology Specialists-Charlotte
  - Charlotte, North Carolina, Forente stater, 28211
    - Levine Cancer Institute-SouthPark
  - Charlotte, North Carolina, Forente stater, 28277
    - Levine Cancer Institute-Ballantyne
  - Charlotte, North Carolina, Forente stater, 28207
    - Novant Health Carolina Surgical - Randolph
  - Clinton, North Carolina, Forente stater, 28328
    - Southeastern Medical Oncology Center-Clinton
  - Clinton, North Carolina, Forente stater, 28328
    - Sampson Radiation Oncology
  - Concord, North Carolina, Forente stater, 28025
    - Atrium Health Cabarrus/LCI-Concord
  - Durham, North Carolina, Forente stater, 27710
    - Duke University Medical Center
  - Fayetteville, North Carolina, Forente stater, 28304
    - Cape Fear Valley Health System
  - Franklin, North Carolina, Forente stater, 28734
    - Angel Medical Center
  - Gastonia, North Carolina, Forente stater, 28054
    - CaroMont Regional Medical Center
  - Gastonia, North Carolina, Forente stater, 28054
    - Gaston Hematology and Oncology Associates
  - Goldsboro, North Carolina, Forente stater, 27534
    - Southeastern Medical Oncology Center-Goldsboro
  - Goldsboro, North Carolina, Forente stater, 27534
    - Wayne Memorial Hospital
  - Goldsboro, North Carolina, Forente stater, 27534
    - Wayne Radiation Oncology
  - Greensboro, North Carolina, Forente stater, 27403
    - Cone Health Cancer Center
  - Henderson, North Carolina, Forente stater, 27536
    - Maria Parham Hospital
  - Hendersonville, North Carolina, Forente stater, 28791
    - Margaret R Pardee Memorial Hospital
  - Hendersonville, North Carolina, Forente stater, 28792
    - AdventHealth Hendersonville
  - High Point, North Carolina, Forente stater, 27262
    - Hayworth Cancer Center
  - High Point, North Carolina, Forente stater, 27262
    - High Point Regional Hospital
  - Huntersville, North Carolina, Forente stater, 28078
    - Novant Health Cancer Institute - Huntersville
  - Huntersville, North Carolina, Forente stater, 28078
    - Southern Oncology Specialists-Huntersville
  - Jacksonville, North Carolina, Forente stater, 28546
    - Southeastern Medical Oncology Center-Jacksonville
  - Jacksonville, North Carolina, Forente stater, 28546
    - Onslow Memorial Hospital
  - Kinston, North Carolina, Forente stater, 28501
    - Vidant Oncology-Kinston
  - Laurinburg, North Carolina, Forente stater, 28352
    - Scotland Memorial Hospital-Laurinburg Cancer Center
  - Leland, North Carolina, Forente stater, 28451
    - Cape Fear Cancer Specialists-Leland
  - Lumberton, North Carolina, Forente stater, 28358
    - Southeastern Regional Medical Center
  - Marion, North Carolina, Forente stater, 28752
    - Mission Hospital McDowell
  - Matthews, North Carolina, Forente stater, 28105
    - Matthews Radiation Oncology Center
  - Matthews, North Carolina, Forente stater, 28105
    - Novant Health Cancer Institute - Matthews
  - Mebane, North Carolina, Forente stater, 27302
    - Cone Heath Cancer Center at Mebane
  - Monroe, North Carolina, Forente stater, 28112
    - Atrium Health Union/LCI-Union
  - Mooresville, North Carolina, Forente stater, 28117
    - Novant Health Cancer Institute - Mooresville
  - Oxford, North Carolina, Forente stater, 27565
    - Granville Medical Center
  - Raleigh, North Carolina, Forente stater, 27607
    - UNC Rex Healthcare
  - Raleigh, North Carolina, Forente stater, 27609
    - Duke Raleigh Hospital
  - Raleigh, North Carolina, Forente stater, 27614
    - UNC Rex Cancer Center of Wakefield
  - Reidsville, North Carolina, Forente stater, 27320
    - Annie Penn Memorial Hospital
  - Roxboro, North Carolina, Forente stater, 27573
    - Person Memorial Hospital
  - Rutherfordton, North Carolina, Forente stater, 28139
    - Rutherford Hospital
  - Shelby, North Carolina, Forente stater, 28150
    - Atrium Health Cleveland/LCI-Cleveland
  - Shelby, North Carolina, Forente stater, 28150
    - Cleveland Hematology and Oncology Associates PC
  - Smithfield, North Carolina, Forente stater, 27577
    - Johnston Memorial Hospital
  - Spruce Pine, North Carolina, Forente stater, 28777
    - Blue Ridge Regional Hospital
  - Statesville, North Carolina, Forente stater, 28677
    - Iredell Memorial Hospital
  - Washington, North Carolina, Forente stater, 27889
    - Marion L Shepard Cancer Center at Vidant Beaufort Hospital
  - Wilmington, North Carolina, Forente stater, 28401
    - Novant Health New Hanover Regional Medical Center
  - Wilmington, North Carolina, Forente stater, 28401
    - Cape Fear Cancer Specialists
  - Winston-Salem, North Carolina, Forente stater, 27157
    - Wake Forest University Health Sciences
  - Winston-Salem, North Carolina, Forente stater, 27104
    - Southeast Clinical Oncology Research Consortium NCORP
- North Dakota
  - Bismarck, North Dakota, Forente stater, 58501
    - Sanford Bismarck Medical Center
  - Bismarck, North Dakota, Forente stater, 58501
    - Mid Dakota Clinic
  - Bismarck, North Dakota, Forente stater, 58501
    - Saint Alexius Medical Center
  - Grand Forks, North Dakota, Forente stater, 58201
    - Altru Cancer Center
  - Minot, North Dakota, Forente stater, 58701
    - Trinity Cancer Care Center
- Ohio
  - Akron, Ohio, Forente stater, 44307
    - Cleveland Clinic Akron General
  - Akron, Ohio, Forente stater, 44304
    - Summa Health System - Akron Campus
  - Barberton, Ohio, Forente stater, 44203
    - Summa Health System - Barberton Campus
  - Beachwood, Ohio, Forente stater, 44122
    - UHHS-Chagrin Highlands Medical Center
  - Beachwood, Ohio, Forente stater, 44122
    - Cleveland Clinic Cancer Center Beachwood
  - Beavercreek, Ohio, Forente stater, 45431
    - Indu and Raj Soin Medical Center
  - Bellefontaine, Ohio, Forente stater, 43311
    - Mary Rutan Hospital
  - Belpre, Ohio, Forente stater, 45714
    - Strecker Cancer Center-Belpre
  - Bowling Green, Ohio, Forente stater, 43402
    - Toledo Clinic Cancer Centers-Bowling Green
  - Canton, Ohio, Forente stater, 44710
    - Aultman Health Foundation
  - Centerville, Ohio, Forente stater, 45459
    - Miami Valley Hospital South
  - Chardon, Ohio, Forente stater, 44024
    - Geauga Hospital
  - Chillicothe, Ohio, Forente stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forente stater, 45219
    - The Christ Hospital
  - Cincinnati, Ohio, Forente stater, 45219
    - University of Cincinnati Cancer Center-UC Medical Center
  - Cincinnati, Ohio, Forente stater, 45220
    - Good Samaritan Hospital - Cincinnati
  - Cincinnati, Ohio, Forente stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forente stater, 45242
    - Oncology Hematology Care Inc-Blue Ash
  - Cincinnati, Ohio, Forente stater, 45202
    - Oncology Hematology Care Inc-Eden Park
  - Cincinnati, Ohio, Forente stater, 45211
    - Oncology Hematology Care Inc-Mercy West
  - Cincinnati, Ohio, Forente stater, 45230
    - Oncology Hematology Care Inc-Anderson
  - Cincinnati, Ohio, Forente stater, 45236
    - Oncology Hematology Care Inc-Kenwood
  - Cincinnati, Ohio, Forente stater, 45247
    - TriHealth Cancer Institute-Westside
  - Cincinnati, Ohio, Forente stater, 45255
    - TriHealth Cancer Institute-Anderson
  - Cleveland, Ohio, Forente stater, 44106
    - Case Western Reserve University
  - Cleveland, Ohio, Forente stater, 44109
    - MetroHealth Medical Center
  - Cleveland, Ohio, Forente stater, 44195
    - Cleveland Clinic Foundation
  - Cleveland, Ohio, Forente stater, 44111
    - Cleveland Clinic Cancer Center/Fairview Hospital
  - Clyde, Ohio, Forente stater, 43410
    - North Coast Cancer Care-Clyde
  - Columbus, Ohio, Forente stater, 43214
    - Riverside Methodist Hospital
  - Columbus, Ohio, Forente stater, 43210
    - Ohio State University Comprehensive Cancer Center
  - Columbus, Ohio, Forente stater, 43219
    - The Mark H Zangmeister Center
  - Columbus, Ohio, Forente stater, 43214
    - Columbus Oncology and Hematology Associates Inc
  - Columbus, Ohio, Forente stater, 43228
    - Doctors Hospital
  - Columbus, Ohio, Forente stater, 43213
    - Mount Carmel East Hospital
  - Columbus, Ohio, Forente stater, 43215
    - Grant Medical Center
  - Columbus, Ohio, Forente stater, 43222
    - Mount Carmel Health Center West
  - Columbus, Ohio, Forente stater, 43215
    - Columbus NCI Community Oncology Research Program
  - Dayton, Ohio, Forente stater, 45406
    - Good Samaritan Hospital - Dayton
  - Dayton, Ohio, Forente stater, 45409
    - Miami Valley Hospital
  - Dayton, Ohio, Forente stater, 45415
    - Miami Valley Hospital North
  - Dayton, Ohio, Forente stater, 45405
    - Grandview Hospital
  - Dayton, Ohio, Forente stater, 45459
    - Dayton NCI Community Oncology Research Program
  - Delaware, Ohio, Forente stater, 43015
    - Delaware Health Center-Grady Cancer Center
  - Delaware, Ohio, Forente stater, 43015
    - Delaware Radiation Oncology
  - Delaware, Ohio, Forente stater, 43015
    - Grady Memorial Hospital
  - Elyria, Ohio, Forente stater, 44035
    - Mercy Cancer Center-Elyria
  - Elyria, Ohio, Forente stater, 44035
    - Hematology Oncology Center Incorporated
  - Fairfield, Ohio, Forente stater, 45014
    - Oncology Hematology Care Inc-Healthplex
  - Findlay, Ohio, Forente stater, 45840
    - Blanchard Valley Hospital
  - Franklin, Ohio, Forente stater, 45005-1066
    - Atrium Medical Center-Middletown Regional Hospital
  - Greenville, Ohio, Forente stater, 45331
    - Wayne Hospital
  - Independence, Ohio, Forente stater, 44131
    - Cleveland Clinic Cancer Center Independence
  - Kettering, Ohio, Forente stater, 45429
    - Kettering Medical Center
  - Kettering, Ohio, Forente stater, 45420
    - First Dayton Cancer Care
  - Lancaster, Ohio, Forente stater, 43130
    - Fairfield Medical Center
  - Lancaster, Ohio, Forente stater, 43130
    - Lancaster Radiation Oncology
  - Lima, Ohio, Forente stater, 45801
    - Saint Rita's Medical Center
  - Lima, Ohio, Forente stater, 45804
    - Lima Memorial Hospital
  - Mansfield, Ohio, Forente stater, 44906
    - Cleveland Clinic Cancer Center Mansfield
  - Mansfield, Ohio, Forente stater, 44903
    - OhioHealth Mansfield Hospital
  - Marietta, Ohio, Forente stater, 45750
    - Marietta Memorial Hospital
  - Maumee, Ohio, Forente stater, 43537
    - Toledo Clinic Cancer Centers-Maumee
  - Maumee, Ohio, Forente stater, 43537
    - Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
  - Mayfield Heights, Ohio, Forente stater, 44124
    - Hillcrest Hospital Cancer Center
  - Mayfield Heights, Ohio, Forente stater, 44124
    - UH Seidman Cancer Center at Landerbrook Health Center
  - Medina, Ohio, Forente stater, 44256
    - Summa Health Medina Medical Center
  - Mentor, Ohio, Forente stater, 44060
    - UH Seidman Cancer Center at Lake Health Mentor Campus
  - Middleburg Heights, Ohio, Forente stater, 44130
    - UH Seidman Cancer Center at Southwest General Hospital
  - Mount Vernon, Ohio, Forente stater, 43050
    - Knox Community Hospital
  - Newark, Ohio, Forente stater, 43055
    - Licking Memorial Hospital
  - Newark, Ohio, Forente stater, 43055
    - Newark Radiation Oncology
  - Norwalk, Ohio, Forente stater, 44857
    - Fisher-Titus Medical Center
  - Oregon, Ohio, Forente stater, 43616
    - Saint Charles Hospital
  - Oregon, Ohio, Forente stater, 43616
    - Toledo Clinic Cancer Centers-Oregon
  - Parma, Ohio, Forente stater, 44129
    - University Hospitals Parma Medical Center
  - Perrysburg, Ohio, Forente stater, 43551
    - Mercy Health Perrysburg Cancer Center
  - Portsmouth, Ohio, Forente stater, 45662
    - Southern Ohio Medical Center
  - Sandusky, Ohio, Forente stater, 44870
    - North Coast Cancer Care
  - Springfield, Ohio, Forente stater, 45505
    - Springfield Regional Medical Center
  - Springfield, Ohio, Forente stater, 45504
    - Springfield Regional Cancer Center
  - Strongsville, Ohio, Forente stater, 44136
    - Cleveland Clinic Cancer Center Strongsville
  - Sylvania, Ohio, Forente stater, 43560
    - ProMedica Flower Hospital
  - Tiffin, Ohio, Forente stater, 44883
    - Mercy Hospital of Tiffin
  - Toledo, Ohio, Forente stater, 43606
    - ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
  - Toledo, Ohio, Forente stater, 43608
    - Saint Vincent Mercy Medical Center
  - Toledo, Ohio, Forente stater, 43623
    - Mercy Health - Saint Anne Hospital
  - Toledo, Ohio, Forente stater, 43623
    - Toledo Clinic Cancer Centers-Toledo
  - Toledo, Ohio, Forente stater, 43614
    - University of Toledo
  - Toledo, Ohio, Forente stater, 43617
    - Toledo Community Hospital Oncology Program CCOP
  - Troy, Ohio, Forente stater, 45373
    - Upper Valley Medical Center
  - Wadsworth, Ohio, Forente stater, 44281
    - University Hospitals Sharon Health Center
  - Warrensville Heights, Ohio, Forente stater, 44122
    - South Pointe Hospital
  - Wauseon, Ohio, Forente stater, 43567
    - Fulton County Health Center
  - West Chester, Ohio, Forente stater, 45069
    - University of Cincinnati Cancer Center-West Chester
  - Westerville, Ohio, Forente stater, 43081
    - Saint Ann's Hospital
  - Westlake, Ohio, Forente stater, 44145
    - UH Seidman Cancer Center at Saint John Medical Center
  - Westlake, Ohio, Forente stater, 44145
    - UHHS-Westlake Medical Center
  - Wilmington, Ohio, Forente stater, 45177
    - Clinton Memorial Hospital
  - Wooster, Ohio, Forente stater, 44691
    - Cleveland Clinic Wooster Family Health and Surgery Center
  - Wright-Patterson Air Force Base, Ohio, Forente stater, 45433
    - Wright-Patterson Medical Center
  - Xenia, Ohio, Forente stater, 45385
    - Greene Memorial Hospital
  - Zanesville, Ohio, Forente stater, 43701
    - Genesis Healthcare System Cancer Care Center
- Oklahoma
  - Ardmore, Oklahoma, Forente stater, 73401
    - Mercy Clinic Oncology and Hematology-Ardmore
  - Lawton, Oklahoma, Forente stater, 73505
    - Cancer Centers of Southwest Oklahoma Research
  - Norman, Oklahoma, Forente stater, 73071
    - Cancer Care Associates-Norman
  - Oklahoma City, Oklahoma, Forente stater, 73104
    - University of Oklahoma Health Sciences Center
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Mercy Hospital Oklahoma City
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Mercy Physicians of Oklahoma-Lakeside
  - Tulsa, Oklahoma, Forente stater, 74146
    - Oklahoma Cancer Specialists and Research Institute-Tulsa
  - Tulsa, Oklahoma, Forente stater, 74136
    - Natalie Warren Bryant Cancer Center at Saint Francis
  - Tulsa, Oklahoma, Forente stater, 74136
    - Surgical Associates Inc
  - Tulsa, Oklahoma, Forente stater, 74146
    - Warren Clinic Oncology-Tulsa
- Oregon
  - Baker City, Oregon, Forente stater, 97814
    - Saint Alphonsus Medical Center-Baker City
  - Bend, Oregon, Forente stater, 97701
    - Saint Charles Health System
  - Clackamas, Oregon, Forente stater, 97015
    - Clackamas Radiation Oncology Center
  - Clackamas, Oregon, Forente stater, 97015
    - Providence Cancer Institute Clackamas Clinic
  - Coos Bay, Oregon, Forente stater, 97420
    - Bay Area Hospital
  - Corvallis, Oregon, Forente stater, 97330
    - Good Samaritan Hospital
  - Grants Pass, Oregon, Forente stater, 97527
    - Three Rivers Community Hospital
  - Gresham, Oregon, Forente stater, 97030
    - Legacy Mount Hood Medical Center
  - Medford, Oregon, Forente stater, 97504
    - Asante Health System
  - Medford, Oregon, Forente stater, 97504
    - Providence Medford Medical Center
  - Medford, Oregon, Forente stater, 97504
    - Rogue Valley Medical Center
  - Milwaukie, Oregon, Forente stater, 97222
    - Providence Milwaukie Hospital
  - Newberg, Oregon, Forente stater, 97132
    - Providence Newberg Medical Center
  - Ontario, Oregon, Forente stater, 97914
    - Saint Alphonsus Medical Center-Ontario
  - Oregon City, Oregon, Forente stater, 97045
    - Providence Willamette Falls Medical Center
  - Portland, Oregon, Forente stater, 97239
    - Oregon Health and Science University
  - Portland, Oregon, Forente stater, 97210
    - Legacy Good Samaritan Hospital and Medical Center
  - Portland, Oregon, Forente stater, 97213
    - Providence Portland Medical Center
  - Portland, Oregon, Forente stater, 97225
    - Providence Saint Vincent Medical Center
  - Portland, Oregon, Forente stater, 97227
    - Kaiser Permanente Northwest
  - Portland, Oregon, Forente stater, 97227
    - Legacy Emanuel Hospital and Health Center
  - Tualatin, Oregon, Forente stater, 97062
    - Legacy Meridian Park Hospital
- Pennsylvania
  - Abington, Pennsylvania, Forente stater, 19001
    - Jefferson Abington Hospital
  - Allentown, Pennsylvania, Forente stater, 18103
    - Lehigh Valley Hospital-Cedar Crest
  - Beaver, Pennsylvania, Forente stater, 15009
    - UPMC-Heritage Valley Health System Beaver
  - Bethlehem, Pennsylvania, Forente stater, 18017
    - Lehigh Valley Hospital - Muhlenberg
  - Bethlehem, Pennsylvania, Forente stater, 18015
    - Saint Luke's University Hospital-Bethlehem Campus
  - Bryn Mawr, Pennsylvania, Forente stater, 19010
    - Bryn Mawr Hospital
  - Butler, Pennsylvania, Forente stater, 16001
    - Butler Memorial Hospital
  - Carlisle, Pennsylvania, Forente stater, 17015
    - Carlisle Regional Cancer Center
  - Danville, Pennsylvania, Forente stater, 17822
    - Geisinger Medical Center
  - Doylestown, Pennsylvania, Forente stater, 18901
    - Doylestown Hospital
  - Drexel Hill, Pennsylvania, Forente stater, 19026
    - Delaware County Memorial Hospital
  - East Stroudsburg, Pennsylvania, Forente stater, 18301
    - Pocono Medical Center
  - Easton, Pennsylvania, Forente stater, 18042
    - Easton Hospital
  - Ephrata, Pennsylvania, Forente stater, 17522
    - Ephrata Cancer Center
  - Ephrata, Pennsylvania, Forente stater, 17522
    - Ephrata Community Hospital
  - Gettysburg, Pennsylvania, Forente stater, 17325
    - Adams Cancer Center
  - Greensburg, Pennsylvania, Forente stater, 15601
    - UPMC Cancer Centers - Arnold Palmer Pavilion
  - Hanover, Pennsylvania, Forente stater, 17331
    - Cherry Tree Cancer Center
  - Hazleton, Pennsylvania, Forente stater, 18201
    - Geisinger Medical Center-Cancer Center Hazleton
  - Hershey, Pennsylvania, Forente stater, 17033-0850
    - Penn State Milton S Hershey Medical Center
  - Johnstown, Pennsylvania, Forente stater, 15901
    - UPMC-Johnstown/John P. Murtha Regional Cancer Center
  - Lancaster, Pennsylvania, Forente stater, 17602
    - Lancaster General Hospital
  - Lebanon, Pennsylvania, Forente stater, 17042
    - Sechler Family Cancer Center
  - Lewisburg, Pennsylvania, Forente stater, 17837
    - Geisinger Medical Oncology-Lewisburg
  - Lewistown, Pennsylvania, Forente stater, 17044
    - Lewistown Hospital
  - McKeesport, Pennsylvania, Forente stater, 15132
    - UPMC Cancer Center at UPMC McKeesport
  - Media, Pennsylvania, Forente stater, 19063
    - Riddle Memorial Hospital
  - Moon, Pennsylvania, Forente stater, 15108
    - UPMC Hillman Cancer Center in Coraopolis
  - Norristown, Pennsylvania, Forente stater, 19401
    - Suburban Community Hospital and Cancer Center
  - Paoli, Pennsylvania, Forente stater, 19301
    - Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19111
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forente stater, 19107
    - Thomas Jefferson University Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19140
    - Temple University Hospital
  - Philadelphia, Pennsylvania, Forente stater, 19141
    - Einstein Medical Center Philadelphia
  - Philadelphia, Pennsylvania, Forente stater, 19107
    - Pennsylvania Hospital
  - Phoenixville, Pennsylvania, Forente stater, 19460
    - Phoenixville Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15213
    - UPMC-Magee Womens Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15232
    - University of Pittsburgh Cancer Institute (UPCI)
  - Pittsburgh, Pennsylvania, Forente stater, 15232
    - UPMC-Shadyside Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15213
    - UPMC-Presbyterian Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15215
    - UPMC-Saint Margaret
  - Pittsburgh, Pennsylvania, Forente stater, 15236
    - UPMC Jefferson Regional Radiation Oncology
  - Pittsburgh, Pennsylvania, Forente stater, 15237
    - UPMC-Passavant Hospital
  - Pittsburgh, Pennsylvania, Forente stater, 15243
    - UPMC-Saint Clair Hospital Cancer Center
  - Pottstown, Pennsylvania, Forente stater, 19464
    - Pottstown Hospital
  - Pottsville, Pennsylvania, Forente stater, 17901
    - Geisinger Cancer Services-Pottsville
  - Reading, Pennsylvania, Forente stater, 19605
    - Penn State Health Saint Joseph Medical Center
  - Sayre, Pennsylvania, Forente stater, 18840
    - Guthrie Medical Group PC-Robert Packer Hospital
  - Scranton, Pennsylvania, Forente stater, 18510
    - Scranton Hematology Oncology
  - Scranton, Pennsylvania, Forente stater, 18501
    - Mercy Hospital
  - Scranton, Pennsylvania, Forente stater, 18508
    - Hematology and Oncology Associates of North East Pennsylvania
  - Sellersville, Pennsylvania, Forente stater, 18960
    - Grand View Hospital
  - Seneca, Pennsylvania, Forente stater, 16346
    - UPMC Cancer Center at UPMC Northwest
  - State College, Pennsylvania, Forente stater, 16801
    - Geisinger Medical Group
  - State College, Pennsylvania, Forente stater, 16803
    - Mount Nittany Medical Center
  - Uniontown, Pennsylvania, Forente stater, 15401
    - UPMC Uniontown Hospital Radiation Oncology
  - Upland, Pennsylvania, Forente stater, 19013
    - Associates In Hematology Oncology PC-Upland
  - Washington, Pennsylvania, Forente stater, 15301
    - UPMC Washington Hospital Radiation Oncology
  - West Chester, Pennsylvania, Forente stater, 19380
    - Chester County Hospital
  - West Reading, Pennsylvania, Forente stater, 19611
    - Reading Hospital
  - Wilkes-Barre, Pennsylvania, Forente stater, 18711
    - Geisinger Wyoming Valley/Henry Cancer Center
  - Williamsport, Pennsylvania, Forente stater, 17701
    - UPMC Susquehanna
  - Wynnewood, Pennsylvania, Forente stater, 19096
    - Lankenau Medical Center
  - York, Pennsylvania, Forente stater, 17403
    - WellSpan Health-York Cancer Center
  - York, Pennsylvania, Forente stater, 17403
    - WellSpan Health-York Hospital
- Rhode Island
  - Providence, Rhode Island, Forente stater, 02903
    - Rhode Island Hospital
  - Providence, Rhode Island, Forente stater, 02905
    - Women and Infants Hospital
  - Providence, Rhode Island, Forente stater, 02906
    - Miriam Hospital
  - Providence, Rhode Island, Forente stater, 02908
    - Roger Williams Medical Center
  - Warwick, Rhode Island, Forente stater, 02886
    - Kent Hospital
- South Carolina
  - Anderson, South Carolina, Forente stater, 29621
    - AnMed Health Cancer Center
  - Anderson, South Carolina, Forente stater, 29621
    - AnMed Health Hospital
  - Boiling Springs, South Carolina, Forente stater, 29316
    - Prisma Health Cancer Institute - Spartanburg
  - Charleston, South Carolina, Forente stater, 29425
    - Medical University of South Carolina
  - Charleston, South Carolina, Forente stater, 29401
    - Roper Hospital
  - Charleston, South Carolina, Forente stater, 29406
    - Lowcountry Hematology Oncology PA-North Charleston
  - Charleston, South Carolina, Forente stater, 29414
    - Bon Secours Saint Francis Hospital
  - Charleston, South Carolina, Forente stater, 29414
    - Lowcountry Hematology Oncology PA-West Ashley
  - Charleston, South Carolina, Forente stater, 29403
    - Charleston Oncology - Roper
  - Charleston, South Carolina, Forente stater, 29414
    - Charleston Oncology - Saint Francis
  - Clinton, South Carolina, Forente stater, 29325
    - Prisma Health Cancer Institute - Laurens
  - Easley, South Carolina, Forente stater, 29640
    - Prisma Health Cancer Institute - Easley
  - Florence, South Carolina, Forente stater, 29506
    - McLeod Regional Medical Center
  - Gaffney, South Carolina, Forente stater, 29341
    - Gibbs Cancer Center-Gaffney
  - Georgetown, South Carolina, Forente stater, 29440
    - Tidelands Georgetown Memorial Hospital
  - Greenville, South Carolina, Forente stater, 29605
    - Prisma Health Cancer Institute - Faris
  - Greenville, South Carolina, Forente stater, 29607
    - Saint Francis Cancer Center
  - Greenville, South Carolina, Forente stater, 29615
    - Prisma Health Cancer Institute - Eastside
  - Greenville, South Carolina, Forente stater, 29605
    - Prisma Health Cancer Institute - Butternut
  - Greenville, South Carolina, Forente stater, 29601
    - Saint Francis Hospital
  - Greenville, South Carolina, Forente stater, 29605
    - Prisma Health Greenville Memorial Hospital
  - Greenville, South Carolina, Forente stater, 29601
    - Greenville Health System Cancer Institute-Andrews
  - Greenwood, South Carolina, Forente stater, 29646
    - Self Regional Healthcare
  - Greer, South Carolina, Forente stater, 29650
    - Prisma Health Cancer Institute - Greer
  - Greer, South Carolina, Forente stater, 29651
    - Gibbs Cancer Center-Pelham
  - Lancaster, South Carolina, Forente stater, 29720
    - Carolina Blood and Cancer Care Associates PA-Lancaster
  - Mount Pleasant, South Carolina, Forente stater, 29464
    - Lowcountry Hematology Oncology PA-Mount Pleasant
  - Rock Hill, South Carolina, Forente stater, 29732
    - Levine Cancer Institute-Rock Hill
  - Rock Hill, South Carolina, Forente stater, 29732
    - Carolina Blood and Cancer Care Associates PA
  - Seneca, South Carolina, Forente stater, 29672
    - Prisma Health Cancer Institute - Seneca
  - Spartanburg, South Carolina, Forente stater, 29303
    - Spartanburg Medical Center
  - Union, South Carolina, Forente stater, 29379
    - MGC Hematology Oncology-Union
  - West Columbia, South Carolina, Forente stater, 29169
    - Lexington Medical Center
- South Dakota
  - Aberdeen, South Dakota, Forente stater, 57401
    - Avera Cancer Institute-Aberdeen
  - Rapid City, South Dakota, Forente stater, 57701
    - Rapid City Regional Hospital
  - Sioux Falls, South Dakota, Forente stater, 57105
    - Avera Cancer Institute
  - Sioux Falls, South Dakota, Forente stater, 57117-5134
    - Sanford USD Medical Center - Sioux Falls
  - Sioux Falls, South Dakota, Forente stater, 57104
    - Sanford Cancer Center Oncology Clinic
  - Sioux Falls, South Dakota, Forente stater, 57105
    - Medical X-Ray Center
  - Sioux Falls, South Dakota, Forente stater, 57117-5045
    - Avera McKennan Hospital and University Health Center
- Tennessee
  - Bristol, Tennessee, Forente stater, 37620
    - Wellmont Medical Associates Oncology and Hematology-Bristol
  - Bristol, Tennessee, Forente stater, 37620
    - Bristol Regional Medical Center
  - Chattanooga, Tennessee, Forente stater, 37404
    - Memorial Hospital
  - Chattanooga, Tennessee, Forente stater, 37403
    - Erlanger Medical Center
  - Cookeville, Tennessee, Forente stater, 38501
    - Cookeville Regional Medical Center
  - Franklin, Tennessee, Forente stater, 37067
    - Vanderbilt-Ingram Cancer Center Cool Springs
  - Hixson, Tennessee, Forente stater, 37343
    - Pulmonary Medicine Center of Chattanooga-Hixson
  - Johnson City, Tennessee, Forente stater, 37604
    - Wellmont Medical Associates Oncology and Hematology-Johnson City
  - Kingsport, Tennessee, Forente stater, 37660
    - Ballad Health Cancer Care - Kingsport
  - Kingsport, Tennessee, Forente stater, 37660
    - Wellmont Holston Valley Hospital and Medical Center
  - Knoxville, Tennessee, Forente stater, 37916
    - Thompson Cancer Survival Center
  - Knoxville, Tennessee, Forente stater, 37920
    - University of Tennessee - Knoxville
  - Memphis, Tennessee, Forente stater, 38163
    - University of Tennessee Health Science Center
  - Nashville, Tennessee, Forente stater, 37232
    - Vanderbilt University/Ingram Cancer Center
  - Nashville, Tennessee, Forente stater, 37204
    - Vanderbilt Breast Center at One Hundred Oaks
  - Nashville, Tennessee, Forente stater, 37208
    - Meharry Medical College
  - Nashville, Tennessee, Forente stater, 37203
    - Nashville Breast Center
  - Ooltewah, Tennessee, Forente stater, 37363
    - Memorial GYN Plus
- Texas
  - Amarillo, Texas, Forente stater, 79106
    - The Don and Sybil Harrington Cancer Center
  - Austin, Texas, Forente stater, 78701
    - Dell Seton Medical Center at The University of Texas
  - Bryan, Texas, Forente stater, 77802
    - Saint Joseph Regional Cancer Center
  - Conroe, Texas, Forente stater, 77384
    - MD Anderson in The Woodlands
  - Dallas, Texas, Forente stater, 75235
    - Parkland Memorial Hospital
  - Dallas, Texas, Forente stater, 75390
    - UT Southwestern/Simmons Cancer Center-Dallas
  - Dallas, Texas, Forente stater, 75216
    - Dallas VA Medical Center
  - El Paso, Texas, Forente stater, 79905
    - Texas Tech University Health Sciences Center-El Paso
  - Fort Worth, Texas, Forente stater, 76104
    - Baylor All Saints Medical Center at Fort Worth
  - Galveston, Texas, Forente stater, 77555-0565
    - University of Texas Medical Branch
  - Houston, Texas, Forente stater, 77030
    - M D Anderson Cancer Center
  - Houston, Texas, Forente stater, 77026-1967
    - Lyndon Baines Johnson General Hospital
  - Houston, Texas, Forente stater, 77030
    - Houston Methodist Hospital
  - Houston, Texas, Forente stater, 77030
    - Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
  - Houston, Texas, Forente stater, 77079
    - MD Anderson West Houston
  - Irving, Texas, Forente stater, 75061
    - Baylor Medical Center at Irving
  - Laredo, Texas, Forente stater, 78041
    - Doctor's Hospital of Laredo
  - League City, Texas, Forente stater, 77573
    - MD Anderson League City
  - Lubbock, Texas, Forente stater, 79410
    - Covenant Medical Center-Lakeside
  - Lubbock, Texas, Forente stater, 79415
    - UMC Cancer Center / UMC Health System
  - Lubbock, Texas, Forente stater, 79430
    - Texas Tech University Health Sciences Center-Lubbock
  - San Antonio, Texas, Forente stater, 78229
    - University Hospital
  - San Antonio, Texas, Forente stater, 78229
    - University of Texas Health Science Center at San Antonio
  - San Antonio, Texas, Forente stater, 78229
    - Cancer Therapy and Research Center at The UT Health Science Center at San Antonio
  - San Antonio, Texas, Forente stater, 78229
    - Audie L Murphy VA Hospital
  - Sugar Land, Texas, Forente stater, 77478
    - MD Anderson in Sugar Land
  - Temple, Texas, Forente stater, 76508
    - Scott and White Memorial Hospital
  - Tyler, Texas, Forente stater, 75701
    - Blood and Cancer Center of East Texas
- Utah
  - American Fork, Utah, Forente stater, 84003
    - American Fork Hospital / Huntsman Intermountain Cancer Center
  - Cedar City, Utah, Forente stater, 84720
    - Sandra L Maxwell Cancer Center
  - Logan, Utah, Forente stater, 84321
    - Logan Regional Hospital
  - Murray, Utah, Forente stater, 84107
    - Intermountain Medical Center
  - Ogden, Utah, Forente stater, 84403
    - McKay-Dee Hospital Center
  - Provo, Utah, Forente stater, 84604
    - Utah Valley Regional Medical Center
  - Riverton, Utah, Forente stater, 84065
    - Riverton Hospital
  - Saint George, Utah, Forente stater, 84770
    - Saint George Regional Medical Center
  - Salt Lake City, Utah, Forente stater, 84112
    - Huntsman Cancer Institute/University of Utah
  - Salt Lake City, Utah, Forente stater, 84106
    - Utah Cancer Specialists-Salt Lake City
  - Salt Lake City, Utah, Forente stater, 84143
    - LDS Hospital
- Vermont
  - Bennington, Vermont, Forente stater, 05201
    - Southwestern Vermont Medical Center
  - Berlin, Vermont, Forente stater, 05602
    - Central Vermont Medical Center/National Life Cancer Treatment
  - Burlington, Vermont, Forente stater, 05405
    - University of Vermont and State Agricultural College
  - Rutland, Vermont, Forente stater, 05701
    - Rutland Regional Medical Center
- Virginia
  - Bristol, Virginia, Forente stater, 24201
    - Wellmont Medical Associates-Bristol
  - Burke, Virginia, Forente stater, 22015
    - Kaiser Permanente-Burke Medical Center
  - Charlottesville, Virginia, Forente stater, 22908
    - University of Virginia Cancer Center
  - Charlottesville, Virginia, Forente stater, 22901
    - Sentara Martha Jefferson Hospital
  - Danville, Virginia, Forente stater, 24541
    - Danville Regional Medical Center
  - Fredericksburg, Virginia, Forente stater, 22401
    - Fredericksburg Oncology Inc
  - Fredericksburg, Virginia, Forente stater, 22408
    - Hematology Oncology Associates of Fredericksburg Inc
  - Gloucester, Virginia, Forente stater, 23061
    - Peninsula Cancer Institute-Gloucester
  - Lynchburg, Virginia, Forente stater, 24501
    - Centra Lynchburg Hematology-Oncology Clinic Inc
  - McLean, Virginia, Forente stater, 22102
    - Kaiser Permanente Tysons Corner Medical Center
  - Newport News, Virginia, Forente stater, 23601
    - Peninsula Cancer Institute-Newport News
  - Norton, Virginia, Forente stater, 24273
    - Southwest VA Regional Cancer Center
  - Richmond, Virginia, Forente stater, 23298
    - Virginia Commonwealth University/Massey Cancer Center
  - South Hill, Virginia, Forente stater, 23970
    - VCU Community Memorial Health Center
  - Virginia Beach, Virginia, Forente stater, 23454
    - Peninsula Cancer Institute-Cancer Specialists of Tidewater
  - Williamsburg, Virginia, Forente stater, 23185
    - Peninsula Cancer Institute-Williamsburg
- Washington
  - Aberdeen, Washington, Forente stater, 98520
    - Providence Regional Cancer System-Aberdeen
  - Anacortes, Washington, Forente stater, 98221
    - Cancer Care Center at Island Hospital
  - Auburn, Washington, Forente stater, 98001
    - MultiCare Auburn Medical Center
  - Bainbridge Island, Washington, Forente stater, 98110
    - Virginia Mason Bainbridge Island Medical Center
  - Bellevue, Washington, Forente stater, 98004
    - Overlake Medical Center
  - Bellingham, Washington, Forente stater, 98225
    - PeaceHealth Saint Joseph Medical Center
  - Bremerton, Washington, Forente stater, 98310
    - Harrison HealthPartners Hematology and Oncology-Bremerton
  - Bremerton, Washington, Forente stater, 98310
    - Harrison Medical Center
  - Burien, Washington, Forente stater, 98166
    - Highline Medical Center-Main Campus
  - Centralia, Washington, Forente stater, 98531
    - Providence Regional Cancer System-Centralia
  - Edmonds, Washington, Forente stater, 98026
    - Swedish Cancer Institute-Edmonds
  - Enumclaw, Washington, Forente stater, 98022
    - Saint Elizabeth Hospital
  - Everett, Washington, Forente stater, 98201
    - Providence Regional Cancer Partnership
  - Federal Way, Washington, Forente stater, 98002
    - Virginia Mason Federal Way Medical Center
  - Federal Way, Washington, Forente stater, 98003
    - Saint Francis Hospital
  - Gig Harbor, Washington, Forente stater, 98332
    - Tacoma/Valley Radiation Oncology Centers-Gig Harbor
  - Gig Harbor, Washington, Forente stater, 98335
    - MultiCare Gig Harbor Medical Park
  - Issaquah, Washington, Forente stater, 98029
    - Swedish Cancer Institute-Issaquah
  - Kennewick, Washington, Forente stater, 99336
    - Kadlec Clinic Hematology and Oncology
  - Kennewick, Washington, Forente stater, 99336
    - Northwest Cancer Clinic
  - Kirkland, Washington, Forente stater, 98034
    - Seattle Cancer Care Alliance at EvergreenHealth
  - Kirkland, Washington, Forente stater, 98033
    - EvergreenHealth Medical Center
  - Lacey, Washington, Forente stater, 98503
    - Providence Regional Cancer System-Lacey
  - Lakewood, Washington, Forente stater, 98499
    - Saint Clare Hospital
  - Longview, Washington, Forente stater, 98632
    - PeaceHealth Saint John Medical Center
  - Lynnwood, Washington, Forente stater, 98036
    - Virginia Mason Lynnwood Medical Center
  - Mount Vernon, Washington, Forente stater, 98274
    - Skagit Valley Hospital
  - Mount Vernon, Washington, Forente stater, 98274
    - Skagit Regional Health Cancer Care Center
  - Olympia, Washington, Forente stater, 98506-5166
    - Providence - Saint Peter Hospital
  - Olympia, Washington, Forente stater, 98507
    - Capital Medical Center
  - Port Angeles, Washington, Forente stater, 98362
    - Olympic Medical Center
  - Port Townsend, Washington, Forente stater, 98368
    - Jefferson Healthcare
  - Poulsbo, Washington, Forente stater, 98370
    - Harrison HealthPartners Hematology and Oncology-Poulsbo
  - Poulsbo, Washington, Forente stater, 98370
    - Peninsula Cancer Center
  - Puyallup, Washington, Forente stater, 98372
    - MultiCare Good Samaritan Hospital
  - Puyallup, Washington, Forente stater, 98372
    - Tacoma/Valley Radiation Oncology Centers-Puyallup
  - Seattle, Washington, Forente stater, 98109
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forente stater, 98104
    - Harborview Medical Center
  - Seattle, Washington, Forente stater, 98101
    - Virginia Mason Medical Center
  - Seattle, Washington, Forente stater, 98107
    - Swedish Medical Center-Ballard Campus
  - Seattle, Washington, Forente stater, 98122
    - Swedish Medical Center-First Hill
  - Seattle, Washington, Forente stater, 98195
    - University of Washington Medical Center - Montlake
  - Seattle, Washington, Forente stater, 98109
    - FHCC South Lake Union
  - Seattle, Washington, Forente stater, 98112
    - Kaiser Permanente Washington
  - Seattle, Washington, Forente stater, 98104
    - Minor and James Medical PLLC
  - Seattle, Washington, Forente stater, 98104
    - Pacific Gynecology Specialists
  - Seattle, Washington, Forente stater, 98104
    - Pacific Medical Center-First Hill
  - Seattle, Washington, Forente stater, 98122-5711
    - Swedish Medical Center-Cherry Hill
  - Sedro-Woolley, Washington, Forente stater, 98284
    - PeaceHealth United General Medical Center
  - Sequim, Washington, Forente stater, 98384
    - Olympic Medical Cancer Care Center
  - Shelton, Washington, Forente stater, 98584
    - Providence Regional Cancer System-Shelton
  - Spokane, Washington, Forente stater, 99218
    - Evergreen Hematology and Oncology PS
  - Spokane, Washington, Forente stater, 99202
    - Cancer Care Northwest - Spokane South
  - Spokane, Washington, Forente stater, 99208
    - Spokane Valley Cancer Center-Mayfair
  - Spokane, Washington, Forente stater, 99216
    - Cancer Care Northwest-Valley
  - Spokane, Washington, Forente stater, 99218
    - Cancer Care Northwest-North Spokane
  - Spokane, Washington, Forente stater, 99220
    - Rockwood Clinic
  - Spokane, Washington, Forente stater, 99204
    - MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
  - Spokane, Washington, Forente stater, 99218
    - MultiCare Deaconess Cancer and Blood Specialty Center - North
  - Spokane, Washington, Forente stater, 99216
    - Spokane Valley Cancer Center-Mission
  - Spokane Valley, Washington, Forente stater, 99216
    - MultiCare Deaconess Cancer and Blood Specialty Center - Valley
  - Tacoma, Washington, Forente stater, 98405
    - Northwest Medical Specialties PLLC
  - Tacoma, Washington, Forente stater, 98431
    - Madigan Army Medical Center
  - Tacoma, Washington, Forente stater, 98405
    - MultiCare Tacoma General Hospital
  - Tacoma, Washington, Forente stater, 98405
    - Tacoma/Valley Radiation Oncology Centers-Saint Joe's
  - Tacoma, Washington, Forente stater, 97405
    - Tacoma/Valley Radiation Oncology Centers-Jackson Hall
  - Tacoma, Washington, Forente stater, 98405
    - Franciscan Research Center-Northwest Medical Plaza
  - Tacoma, Washington, Forente stater, 98405
    - MultiCare Allenmore Hospital
  - Tacoma, Washington, Forente stater, 98405
    - Northwest NCI Community Oncology Research Program
  - Tacoma, Washington, Forente stater, 98405
    - Saint Joseph Medical Center
  - Vancouver, Washington, Forente stater, 98686
    - Legacy Salmon Creek Hospital
  - Vancouver, Washington, Forente stater, 98664
    - PeaceHealth Southwest Medical Center
  - Vancouver, Washington, Forente stater, 98684
    - Compass Oncology Vancouver
  - Walla Walla, Washington, Forente stater, 99362
    - Providence Saint Mary Regional Cancer Center
  - Wenatchee, Washington, Forente stater, 98801
    - Wenatchee Valley Hospital and Clinics
  - Yakima, Washington, Forente stater, 98902
    - North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
  - Yelm, Washington, Forente stater, 98597
    - Providence Regional Cancer System-Yelm
- West Virginia
  - Bridgeport, West Virginia, Forente stater, 26330
    - United Hospital Center
  - Charleston, West Virginia, Forente stater, 25304
    - West Virginia University Charleston Division
  - Huntington, West Virginia, Forente stater, 25701
    - Edwards Comprehensive Cancer Center
  - Martinsburg, West Virginia, Forente stater, 25401
    - WVUH-Berkely Medical Center
  - Morgantown, West Virginia, Forente stater, 26506
    - West Virginia University Healthcare
  - Morgantown, West Virginia, Forente stater, 26505
    - Monongalia Hospital
  - Parkersburg, West Virginia, Forente stater, 26101
    - Camden Clark Medical Center
  - Princeton, West Virginia, Forente stater, 24740
    - Princeton Community Hospital
- Wisconsin
  - Antigo, Wisconsin, Forente stater, 54409
    - Langlade Hospital and Cancer Center
  - Appleton, Wisconsin, Forente stater, 54911
    - ThedaCare Regional Cancer Center
  - Appleton, Wisconsin, Forente stater, 54911
    - ThedaCare Regional Medical Center - Appleton
  - Burlington, Wisconsin, Forente stater, 53105
    - Aurora Cancer Care-Southern Lakes VLCC
  - Chippewa Falls, Wisconsin, Forente stater, 54729
    - Marshfield Clinic-Chippewa Center
  - Eau Claire, Wisconsin, Forente stater, 54701
    - Marshfield Medical Center-EC Cancer Center
  - Eau Claire, Wisconsin, Forente stater, 54701
    - Marshfield Clinic Cancer Center at Sacred Heart
  - Fond Du Lac, Wisconsin, Forente stater, 54937
    - Aurora Health Center-Fond du Lac
  - Franklin, Wisconsin, Forente stater, 53132
    - Ascension Saint Francis - Reiman Cancer Center
  - Germantown, Wisconsin, Forente stater, 53022
    - Aurora Health Care Germantown Health Center
  - Grafton, Wisconsin, Forente stater, 53024
    - Aurora Cancer Care-Grafton
  - Green Bay, Wisconsin, Forente stater, 54311
    - Aurora BayCare Medical Center
  - Green Bay, Wisconsin, Forente stater, 54301
    - Saint Vincent Hospital Cancer Center Green Bay
  - Green Bay, Wisconsin, Forente stater, 54303
    - Saint Vincent Hospital Cancer Center at Saint Mary's
  - Green Bay, Wisconsin, Forente stater, 54303
    - Green Bay Oncology Limited at Saint Mary's Hospital
  - Green Bay, Wisconsin, Forente stater, 54301-3526
    - Green Bay Oncology at Saint Vincent Hospital
  - Janesville, Wisconsin, Forente stater, 53548
    - Mercyhealth Hospital and Cancer Center - Janesville
  - Johnson Creek, Wisconsin, Forente stater, 53038
    - UW Cancer Center Johnson Creek
  - Kenosha, Wisconsin, Forente stater, 53142
    - Aurora Cancer Care-Kenosha South
  - La Crosse, Wisconsin, Forente stater, 54601
    - Gundersen Lutheran Medical Center
  - La Crosse, Wisconsin, Forente stater, 54601
    - Mayo Clinic Health System-Franciscan Healthcare
  - Madison, Wisconsin, Forente stater, 53792
    - University of Wisconsin Carbone Cancer Center
  - Manitowoc, Wisconsin, Forente stater, 54221
    - Holy Family Memorial Hospital
  - Marinette, Wisconsin, Forente stater, 54143
    - Aurora Bay Area Medical Group-Marinette
  - Marinette, Wisconsin, Forente stater, 54143
    - Bay Area Medical Center
  - Marshfield, Wisconsin, Forente stater, 54449
    - Marshfield Medical Center-Marshfield
  - Mequon, Wisconsin, Forente stater, 53097
    - Ascension Columbia Saint Mary's Hospital Ozaukee
  - Milwaukee, Wisconsin, Forente stater, 53226
    - Medical College of Wisconsin
  - Milwaukee, Wisconsin, Forente stater, 53209
    - Aurora Cancer Care-Milwaukee
  - Milwaukee, Wisconsin, Forente stater, 53215
    - Aurora Saint Luke's Medical Center
  - Milwaukee, Wisconsin, Forente stater, 53233
    - Aurora Sinai Medical Center
  - Milwaukee, Wisconsin, Forente stater, 53210
    - Ascension Southeast Wisconsin Hospital - Saint Joseph Campus
  - Milwaukee, Wisconsin, Forente stater, 53211
    - Ascension Columbia Saint Mary's Hospital - Milwaukee
  - Minocqua, Wisconsin, Forente stater, 54548
    - Marshfield Clinic-Minocqua Center
  - Mukwonago, Wisconsin, Forente stater, 53149
    - ProHealth D N Greenwald Center
  - New Richmond, Wisconsin, Forente stater, 54017
    - Cancer Center of Western Wisconsin
  - Oconomowoc, Wisconsin, Forente stater, 53066
    - ProHealth Oconomowoc Memorial Hospital
  - Oconto Falls, Wisconsin, Forente stater, 54154
    - Saint Vincent Hospital Cancer Center at Oconto Falls
  - Oshkosh, Wisconsin, Forente stater, 54904
    - Vince Lombardi Cancer Clinic - Oshkosh
  - Racine, Wisconsin, Forente stater, 53406
    - Aurora Cancer Care-Racine
  - Racine, Wisconsin, Forente stater, 53405
    - Ascension All Saints Hospital
  - Rhinelander, Wisconsin, Forente stater, 54501
    - Ascension Saint Mary's Hospital
  - Rice Lake, Wisconsin, Forente stater, 54868
    - Marshfield Medical Center-Rice Lake
  - Sheboygan, Wisconsin, Forente stater, 53081
    - Vince Lombardi Cancer Clinic-Sheboygan
  - Sheboygan, Wisconsin, Forente stater, 53081
    - HSHS Saint Nicholas Hospital
  - Stevens Point, Wisconsin, Forente stater, 54481
    - Ascension Saint Michael's Hospital
  - Stevens Point, Wisconsin, Forente stater, 54482
    - Marshfield Medical Center-River Region at Stevens Point
  - Sturgeon Bay, Wisconsin, Forente stater, 54235-1495
    - Saint Vincent Hospital Cancer Center at Sturgeon Bay
  - Sturgeon Bay, Wisconsin, Forente stater, 54235
    - Green Bay Oncology - Sturgeon Bay
  - Summit, Wisconsin, Forente stater, 53066
    - Aurora Medical Center in Summit
  - Two Rivers, Wisconsin, Forente stater, 54241
    - Vince Lombardi Cancer Clinic-Two Rivers
  - Waukesha, Wisconsin, Forente stater, 53188
    - UW Cancer Center at ProHealth Care
  - Waukesha, Wisconsin, Forente stater, 53188
    - ProHealth Waukesha Memorial Hospital
  - Waukesha, Wisconsin, Forente stater, 53188
    - Aurora Cancer Care-Waukesha
  - Wausau, Wisconsin, Forente stater, 54401
    - Aspirus Regional Cancer Center
  - Wausau, Wisconsin, Forente stater, 54401
    - Marshfield Clinic-Wausau Center
  - Wauwatosa, Wisconsin, Forente stater, 53226
    - Aurora Cancer Care-Milwaukee West
  - West Allis, Wisconsin, Forente stater, 53227
    - Aurora West Allis Medical Center
  - Weston, Wisconsin, Forente stater, 54476
    - Marshfield Medical Center - Weston
  - Wisconsin Rapids, Wisconsin, Forente stater, 54494
    - Aspirus Cancer Care - Wisconsin Rapids
  - Wisconsin Rapids, Wisconsin, Forente stater, 54494
    - Marshfield Clinic - Wisconsin Rapids Center
- Wyoming
  - Casper, Wyoming, Forente stater, 82609
    - Rocky Mountain Oncology
  - Cheyenne, Wyoming, Forente stater, 82001
    - Cheyenne Regional Medical Center-West
  - Cody, Wyoming, Forente stater, 82414
    - Big Horn Basin Cancer Center
  - Cody, Wyoming, Forente stater, 82414
    - Billings Clinic-Cody
  - Sheridan, Wyoming, Forente stater, 82801
    - Welch Cancer Center
Frankrike
- - Angers, Frankrike, 49055
    - Institut de Cancerologie de l'Ouest- Angers
  - Auch, Frankrike, 32008
    - Centre Hospitalier d'Auch
  - Avignon, Frankrike, 84918
    - Institut Sainte Catherine
  - Bayonne, Frankrike, 64109
    - Centre Hospitalier de la Côte Basque
  - Bayonne, Frankrike, 64100
    - Centre d'Oncologie et de Radiotherapie Pays Basque
  - Beauvais, Frankrike, 60021
    - Centre Hospitalier de Beauvais
  - Blois, Frankrike, 41016
    - Centre Hospitalier de Blois
  - Bordeaux, Frankrike, 33076
    - Institut Bergonie Cancer Center
  - Bordeaux, Frankrike, 33000
    - Clinique Tivoli Ducos
  - Bordeaux, Frankrike, 33077
    - Polyclinic Bordeaux Nord Aquitaine
  - Brest, Frankrike, 29609
    - CHU de Brest-Hopital Morvan
  - Caen, Frankrike, 14076
    - Centre François Baclesse
  - Clermont-Ferrand, Frankrike, 63000
    - Centre Jean Perrin
  - Creteil, Frankrike, 94000
    - Centre Hospitlier Intercommunal de Creteil
  - Dechy, Frankrike, 59187
    - Centre Hospitalier de Douai
  - Dijon, Frankrike, 21079
    - Centre Georges-François Leclerc
  - Guilherand-Granges, Frankrike, 07500
    - Hopital Prive Drome Ardeche-Clinique Pasteur
  - La Roche Sur Yon, Frankrike, 85925
    - Departemental Hospitalier Roche-sur-Yon (Les Oudairies)
  - Le Havre, Frankrike, 76620
    - Hopital Prive de l'Estuaire
  - Le Mans, Frankrike, 72000
    - Clinique Victor Hugo-Centre Jean Bernard
  - Lille, Frankrike, 59020
    - centre Oscar lambert
  - Limoges, Frankrike, 87042
    - CHU Limoges - Hopital Dupuytren
  - Limoges, Frankrike, 87039
    - Clinique Chenieux
  - Lyon, Frankrike, 69373
    - Centre Leon Bérard
  - Lyon, Frankrike, 69008
    - Hopital Prive Jean Mermoz
  - Marseile, Frankrike, 13009
    - Hopital Prive Clairval
  - Montelimar, Frankrike, 26216
    - Centre Hospitalier de Montelimar
  - Nantes, Frankrike, 44202
    - Centre Catherine de Sienne
  - Neuilly-Sur-Seine, Frankrike, 92200
    - Clinique Hartmann
  - Nice, Frankrike, 06189
    - Centre Antoine Lacassagne
  - Orleans, Frankrike, 45000
    - Hospital De La Source
  - Paris, Frankrike, 75010
    - Hopital Saint Louis
  - Paris, Frankrike, 75005
    - Institut Curie Paris
  - Paris, Frankrike, 75013
    - Hopital Prive des Peupliers
  - Paris, Frankrike, 75651
    - Hôpital La Pitié-Salpétrière
  - Pau, Frankrike, 64000
    - Centre Hopitalier
  - Perigueux, Frankrike, 24000
    - Polyclinique Francheville
  - Perpignan, Frankrike, 66046
    - Centre Hospitalier de Perpignan
  - Perpignan, Frankrike, 66000
    - Clinical Saint-Pierre/Centre Catalan d?Oncologie
  - Pontoise, Frankrike, 95300
    - Centre hospitalier Rene Dubos Pontoise
  - Reims, Frankrike, 51100
    - Institut Jean Godinot
  - Rouen, Frankrike, 76038
    - Centre Henri Becquerel
  - Saint Cloud, Frankrike, 92210
    - Institut Curie-Centre Rene Huguenin Saint Cloud
  - Saint Gregoire, Frankrike, 33760
    - Centre Hospitalier Privé Saint-Grégoire
  - Saint Herblain, Frankrike, 44805
    - Institut de Cancerologie de l'Ouest-Rene Gauducheau
  - Saint-Nazaire, Frankrike, 44606
    - Clinique Mutualiste de l'Estuaire
  - Sarcelles, Frankrike, 95200
    - Centre de Cancerologie Paris Nord
  - Senlis, Frankrike, 60309
    - Groupe Hospitalier Public du Sud de l'Oise Senlis
  - Strasbourg, Frankrike, 67000
    - Centre Paul Strauss
  - Strasbourg, Frankrike, 67091
    - CHRU Strasbourg - Hospital Civil
  - Tarbes, Frankrike, 65000
    - Polyclinique de l'Ormeau
  - Thonon Les Bains, Frankrike, 74200
    - Hopitaux du Leman
  - Toulouse, Frankrike, 31076
    - Clinique Pasteur
  - Toulouse, Frankrike, 31052
    - Center Claudius Regaud
  - Toulouse, Frankrike, 31077
    - Clinique Saint-Jean Languedoc
  - Tours, Frankrike, 37044
    - Hospital Bretonneau
  - Vandoeuvre-les-Nancy, Frankrike, 54511
    - Centre Alexis Vautrin
  - Villejuif, Frankrike, 94805
    - Gustave Roussy
  - Villeneuve, Frankrike, 59657
    - Hopital Prive de Villeneuve d'Ascq
Irland
- - Cork, Irland
    - Cork University Hospital
  - Dublin, Irland, 8
    - Saint James Hospital
  - Letterkenny, Irland, Co Donegal
    - Letterkenny General Hospital
- Co Cork
  - Cork, Co Cork, Irland
    - Bon Secours Hospital
- Co Dublin
  - Dublin, Co Dublin, Irland, 24
    - Tallaght University Hospital
  - Dublin, Co Dublin, Irland, 4
    - Saint Vincent's University Hospital
  - Dublin, Co Dublin, Irland, 7
    - Mater Misericordiae University Hospital
  - Dublin, Co Dublin, Irland, 7
    - Mater Private Hospital
  - Dublin, Co Dublin, Irland, 9
    - Beaumont Hospital
  - Merrion, Co Dublin, Irland, 4
    - Saint Vincent's Private Hospital
- Co Galway
  - Galway, Co Galway, Irland
    - University College Hospital Galway
- Co Limerick
  - Limerick, Co Limerick, Irland, 9
    - Mid-Western Regional Hospital
- Co Sligo
  - Sligo, Co Sligo, Irland
    - Sligo University Hospital
- Co Waterford
  - Waterford, Co Waterford, Irland, 9
    - University Hospital Waterford
Korea, Republikken
- - Seoul, Korea, Republikken, 05505
    - Asan Medical Center
- Gyeonggi-do
  - Goyang-si, Gyeonggi-do, Korea, Republikken, 410-769
    - National Cancer Center-Korea
- Kyeonggi-do
  - Seongnam City, Kyeonggi-do, Korea, Republikken, 463-707
    - Seoul National University Bundang Hospital
Mexico
- Tlalpan
  - Mexico City, Tlalpan, Mexico, 14080
    - Instituto Nacional De Cancerologia de Mexico
Puerto Rico
- - Bayamon, Puerto Rico, 00959-5060
    - Cancer Center-Metro Medical Center Bayamon
  - Manati, Puerto Rico, 00674
    - Doctors Cancer Center
  - San Juan, Puerto Rico, 00917
    - San Juan Community Oncology Group
  - San Juan, Puerto Rico, 00936
    - San Juan City Hospital
Saudi-Arabia
- - Riyadh, Saudi-Arabia, 11211
    - King Faisal Specialist Hospital and Research Centre
Spania
- - Albacete, Spania, 02006
    - Complejo Hospitalario Universitario de Albacete
  - Barcelona, Spania, 08036
    - Hospital Clinic de Barcelona
  - Barcelona, Spania, 08025
    - Hospital de la Santa Creu i Sant Pau
  - Barcelona, Spania, 08916
    - Hospital Universitari Germans Trias I Pujol
  - Caceres, Spania, 10003
    - Hospital San Pedro de Alcántara
  - Castellon, Spania, 12002
    - Hospital Provincial de Castellon
  - Coruna, Spania, 15009
    - Centro Oncologico de Galicia
  - Girona, Spania, 17007
    - Hospital Universitari de Girona Doctor Josep Trueta
  - Girona, Spania, 08907
    - Institut Catalad'Oncologia
  - Madrid, Spania, 28034
    - Hospital Universitario Ramón y Cajal
  - Madrid, Spania, 28007
    - Hospital Universitario Gregorio Maranon
  - Madrid, Spania, 28981
    - Hospital Infanta Cristina de Parla
  - Malaga, Spania, 29010
    - Hospital Clinico Universitario Virgen de la Victoria
  - San Sebastian, Spania, 20014
    - Hospital Nuestra Senora de Aranzazu
  - San Sebastian, Spania, 20014
    - Onkologikoa
  - San Sebastian, Spania, 28700
    - Grupo Espanol de Investigacion en Cancer de Mama
  - Sevilla, Spania, 41013
    - Hospital Universitario Virgen del Rocio
  - Toledo, Spania, 45004
    - Hospital Virgen de la Salud
  - Valencia, Spania, 46010
    - Hospital Clinico Universitario De Valencia
  - Valencia, Spania, 46009
    - Instituto Valenciano de Oncología
  - Zaragoza, Spania, 50009
    - Hospital Clínico Universitario Lozano Blesa
  - Zaragoza, Spania, 50009
    - Hospital Universitario Miguel Servet

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Beskrivelse

Inklusjonskriterier:

Pasienter må ha en histologisk bekreftet diagnose av nodepositivt (1-3 noder) invasivt brystkarsinom med positiv østrogen- og/eller progesteronreseptorstatus, og negativ HER-2-status; østrogen- og progesteronreseptorpositivitet må vurderes i henhold til American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) retningslinjer som enten østrogenreseptor (ER) eller progesteronreseptor (PR) >= 1 % positiv nukleær farging; HER-2 testresultatnegativitet må vurderes i henhold til ASCO/CAP 2013 retningslinjer ved bruk av immunhistokjemi (IHC), in situ hybridisering (ISH) eller begge deler; HER-2 er negativ hvis en enkelt test (eller alle tester) utført i en svulstprøve viser: a) IHC-negativ (0 eller 1+) eller b) ISH-negativ ved bruk av enkeltprobe eller dobbelprobe (gjennomsnittlig HER-2 kopiantall < 4,0 signaler per celle ved enkel probe eller HER-2/CEP-rasjon < 2,0 med et gjennomsnittlig kopiantall < 4,0 signaler per celle ved dobbel probe); hvis HER-2 IHC er 2+, må evaluering for genamplifikasjon (ISH) utføres og ISH må være negativ; ISH er ikke nødvendig hvis IHC er 0 eller 1+; HER-2 equivocal er ikke kvalifisert
Pasienter med multifokal, multisentrisk og synkron bilateral brystkreft er tillatt
- Multifokal sykdom er definert som mer enn én invasiv kreft < 2 cm fra den største lesjonen innenfor samme brystkvadrant; (MERK: Oncotype DX-testingen må fullføres på den største lesjonen)
- Multisentrisk sykdom er definert som mer enn én invasiv kreft >= 2 cm fra den største lesjonen innenfor samme brystkvadrant eller mer enn én lesjon i forskjellige kvadranter (MERK: Oncotype DX-testing bør fullføres på alle svulster og bestemmelsen for kvalifisering bør være laget på høyeste poengsum for gjentakelse)
- Synkron bilateral sykdom er definert som invasiv brystkreft med positive lymfeknuter (aksillære eller intramammære) i minst ett bryst, diagnostisert innen 30 dager etter hverandre; (MERK: Oncotype DX-testingen bør fullføres på begge svulstene og svulsten med høyest residivscore bør brukes)
Pasienter vil ha gjennomgått aksillær stadieinndeling ved vaktpostknutebiopsi eller aksillære lymfeknuterdisseksjon (ALND); pasienter må ha minst én, men ikke mer enn tre kjente positive lymfeknuter (pN1a, pN1b eller pN1c); pasienter med mikrometastaser som eneste nodal involvering (pN1mi) er ikke kvalifisert; pasienter med positiv sentinel node er ikke pålagt å gjennomgå full aksillær lymfeknutedisseksjon; dette er etter den behandlende legens skjønn; aksillær node-evaluering skal utføres i henhold til standarden for omsorg ved hver institusjon
Pasienter med en tidligere diagnose av kontralateralt duktalt karsinom in situ (DCIS) er kvalifisert hvis de gjennomgikk en mastektomi eller lumpektomi med helbryststråling; tidligere delvis brystbestråling, inkludert brakyterapi, er ikke tillatt; Pasienter med en tidligere diagnose av ipsilateral DCIS eller invasiv brystkreft som mottok stråling til det brystet er ikke kvalifisert
Pasienter må enten ha hatt brystbevarende kirurgi med planlagt strålebehandling eller total mastektomi (med eller uten planlagt postmastektomi stråling); pasienter må ha klare marginer fra både invasiv brystkreft og DCIS (i henhold til lokale institusjonelle retningslinjer); lobulært karsinom in situ (LCIS) i kantene er tillatt
Registrering av pasienter som ennå ikke har gjennomgått Oncotype DX-screening må skje senest 56 dager etter endelig operasjon; (for alle pasienter, trinn 2-registrering må skje innen 84 dager etter endelig operasjon); hvis Oncotype DX brystkreftanalyse ikke er utført, må pasienter være villige til å sende inn vevsprøver for testing for å bestemme verdien for tilbakefallsscore; en representativ blokk eller ufargede seksjoner fra den representative blokken sendes direkte til Genomic Health for Oncotype DX Breast Cancer Assay som vil bli utført i henhold til standard kommersiell prosess
- Hvis Oncotype DX-residivscore allerede er kjent og er 25 eller mindre, må pasienten registreres til trinn 2 umiddelbart etter registreringen i trinn 1; hvis Oncotype DX-residivpoengene allerede er kjent og er større enn 25, er pasienten ikke kvalifisert
Pasienter må være kvinner >= 18 år. Siden Oncotype DX-residivskåren ikke er validert hos menn med brystkreft, er menn ikke kvalifisert for denne studien
Pasienter må ha en fullstendig anamnese og fysisk undersøkelse innen 28 dager før registrering
Pasienter må ha en prestasjonsstatus på 0-2 etter Zubrod-kriterier
Pasienter må kunne motta taxan- og/eller antracyklinbasert kjemoterapi
Pasienter må ikke ha mottatt en aromatasehemmer (AI) eller en selektiv østrogenreseptormodulator (SERM) som tamoxifen eller raloxifen innen 5 år før registrering
Ingen annen tidligere malignitet er tillatt bortsett fra tilstrekkelig behandlet basalcelle (eller plateepitel) hudkreft, in situ livmorhalskreft eller annen kreft som pasienten har vært sykdomsfri for i 5 år
Livskvalitet og økonomisk delstudie er permanent stengt for opptjening fra og med 12/1/12; pasienter som samtykket til QOL før 12/1/12 bør fortsette å fylle ut QOL-skjemaer i henhold til deres forventningsrapport; pasienter som er i stand til å fylle ut et spørreskjema på engelsk må tilbys muligheten til å delta i Quality of Life and Economic Substudy; (Livskvalitet og økonomisk delstudie er KUN tilgjengelig for amerikanske INSTITUTIONER); pasienter som ikke er i stand til å fylle ut et spørreskjema på engelsk, registreres på S1007 uten å delta i livskvalitet og økonomisk delstudie
- Pasienter som samtykker i å delta i livskvalitet og økonomisk delstudie og som ennå ikke kjenner resultatene av Oncotype DX-screeningen, må godta å fylle ut spørreskjemaet S1007 helserelatert livskvalitet: Påmelding mellom 14 dager før og 7 dager etter Trinn 1 Registrering
- Pasienter som samtykker i å delta i livskvalitet og økonomisk delstudie og som allerede kjenner sin Oncotype DX-residivpoeng (og den er 25 eller mindre), vil fortsette til trinn 2-registrering uten å fylle ut S1007 helserelatert livskvalitetsspørreskjema. (men vil fylle ut S1007 Health-Relatert Quality of Life Questionnaire: Randomized Study Form)
Pasienter eller deres lovlig autoriserte representant må informeres om undersøkelseskarakteren til denne studien og må signere og gi skriftlig informert samtykke i samsvar med institusjonelle og føderale retningslinjer; for trinn 1-registrering av pasienter som ennå ikke har sendt inn prøver for Oncotype DX brystkreftanalyse, er det riktige samtykkeskjemaet trinn 1-samtykkeskjemaet; for både trinn 1- og trinn 2-registrering av pasienter hvis tilbakefallspoeng allerede er kjent og er 25 eller mindre, er det riktige samtykkeskjemaet trinn 2-samtykkeskjemaet
Som en del av registreringsprosessen for Oncology Patient Enrollment Network (OPEN) oppgis den behandlende institusjonens identitet for å sikre at den gjeldende (innen 365 dager) datoen for godkjenning av institusjonsvurderingskomiteen for denne studien er lagt inn i systemet
TRINN 2 REGISTRERING
Gjentakelsespoeng (RS) av Oncotype DX må være =< 25
Trinn 2 Registrering må finne sted innen 84 dager etter endelig operasjon; Pasienter må ikke ha startet kjemoterapi eller endokrin behandling for brystkreft før randomisering
Pasienter som er randomisert til en av armene kan også delta i fase III-studier som sammenligner lokale terapier, eller sammenligne systemiske terapier (som kjemoterapi, hvis de er randomisert til arm I av S1007)
Livskvalitet og økonomisk delstudie er permanent stengt for opptjening fra og med 12/1/12; Pasienter ved US INSTITUTIONS som samtykker i å delta i Quality of Life and Economic Substudy må godta å fylle ut S1007 Health-Related Quality of Life Questionnaire: Randomized Study Form after Recurrence Score-resultater og randomisert behandlingsstatus er kjent, men før behandlingen er igangsatt
Pasienter eller deres lovlig autoriserte representant må informeres om undersøkelseskarakteren til denne studien og må signere og gi skriftlig informert samtykke i samsvar med institusjonelle og føderale retningslinjer; for alle pasienter er det riktige samtykkeskjemaet for denne registreringen trinn 2-samtykke
TRINN 3 REGISTRERING CBALR TM delstudie
Pasienter må være sykdomsfrie, uten tidligere invasiv tilbakefall på tidspunktet for registrering til trinn 3
Pasienter må registreres til trinn 3 ikke mer enn 8 år etter randomisering (trinn 2-registrering) og må godta å få tatt prøver innen 28 dager etter registrering til trinn 3
Pasienter må godta å få tatt blodprøver på opptil 3 tidspunkter: 1) innen 28 dager etter registrering til trinn 3, 2) 2-3 år etter tidspunkt for registrering til trinn 3, og 3) Ved tidspunkt for invasiv tilbakefall (hvis aktuelt) ). Pasienter må også godta å få innsendt vev på tidspunktet for invasivt tilbakefall (hvis aktuelt) fra den invasive residivbiopsien (der vev er tilgjengelig)

Ekskluderingskriterier:

Pasienter må ikke ha inflammatorisk brystkreft og må ikke ha metastatisk sykdom
Pasienter skal ikke ha påbegynt kjemoterapi eller endokrin behandling for brystkreft før registrering
Pasienter må ikke kreve kronisk behandling med systemiske steroider (inhalasjonssteroider er tillatt) eller andre immunsuppressive midler
Pasienter må ikke være gravide eller ammende; kvinner med reproduktivt potensial må ha samtykket til å bruke en effektiv prevensjonsmetode; en kvinne anses å ha "reproduktivt potensial" hvis hun har hatt menstruasjon på noe tidspunkt i løpet av de foregående 12 påfølgende månedene; i tillegg til rutineprevensjonsmetoder, inkluderer "effektiv prevensjon" også heteroseksuelt sølibat og kirurgi ment å forhindre graviditet (eller med en bivirkning av graviditetsforebygging) definert som hysterektomi, bilateral ooforektomi eller bilateral tubal ligering; men hvis en tidligere sølibatpasient på noe tidspunkt velger å bli heteroseksuelt aktiv i løpet av tidsperioden for bruk av prevensjonstiltak skissert i protokollen, er han/hun ansvarlig for å starte prevensjonstiltak

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Primært formål: Behandling
Tildeling: Randomisert
Intervensjonsmodell: Parallell tildeling
Masking: Ingen (Open Label)

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm	Intervensjon / Behandling
Eksperimentell: Arm I (kjemoterapi og endokrin terapi) Pasienter får et protokoll-godkjent kjemoterapiregime basert på pasientens og/eller legens preferanser. Pasienter får deretter en protokollgodkjent adjuvant endokrin terapi som omfatter tamoxifencitrat, en aromatasehemmer (anastrozol, letrozol eller exemestan), eller begge i 5-10 år i fravær av sykdomsprogresjon eller uakseptabel toksisitet.	Annen: Laboratoriebiomarkøranalyse Korrelative studier Legemiddel: Letrozol Gitt PO Andre navn: CGS 20267 Femara Fempro Legemiddel: Anastrozol Gitt PO Andre navn: Arimidex Anastrazol ICI D1033 ICI-D1033 ZD-1033 Legemiddel: Eksemestan Gitt PO Andre navn: Aromasin FCE-24304 Annen: Livskvalitetsvurdering Hjelpestudier (stengt fra 1.12.12) Andre navn: Livskvalitetsvurdering Legemiddel: Systemisk kjemoterapi Gitt IV Legemiddel: Tamoxifen Citrate Gitt PO Andre navn: Nolvadex TAM Soltamox Apo-Tamox Clonoxifen Dignotamoxi Ebefen Emblon Østroxyn Fentamox Gen-Tamoxifen Genox ICI 46.474 ICI-46474 Jenoxifen Kessar Ledertam Lesporene Nolgen Noltam Nolvadex-D Nourytam Novo-Tamoxifen Novofen Noxitem Oestrifen Oncotam PMS-Tamoxifen Tamax Tamaxin Tamifen Tamizam Tamofen Tamoxasta Tamoxifeni Citras Zemide
Eksperimentell: Arm II (endokrin terapi) Pasienter får en protokoll-godkjent endokrin terapi som omfatter tamoxifen citrat, en aromatasehemmer (anastrozol, letrozol eller exemestan), eller begge deler i 5-10 år i fravær av sykdomsprogresjon eller uakseptabel toksisitet.	Annen: Laboratoriebiomarkøranalyse Korrelative studier Legemiddel: Letrozol Gitt PO Andre navn: CGS 20267 Femara Fempro Legemiddel: Anastrozol Gitt PO Andre navn: Arimidex Anastrazol ICI D1033 ICI-D1033 ZD-1033 Legemiddel: Eksemestan Gitt PO Andre navn: Aromasin FCE-24304 Annen: Livskvalitetsvurdering Hjelpestudier (stengt fra 1.12.12) Andre navn: Livskvalitetsvurdering Legemiddel: Tamoxifen Citrate Gitt PO Andre navn: Nolvadex TAM Soltamox Apo-Tamox Clonoxifen Dignotamoxi Ebefen Emblon Østroxyn Fentamox Gen-Tamoxifen Genox ICI 46.474 ICI-46474 Jenoxifen Kessar Ledertam Lesporene Nolgen Noltam Nolvadex-D Nourytam Novo-Tamoxifen Novofen Noxitem Oestrifen Oncotam PMS-Tamoxifen Tamax Tamaxin Tamifen Tamizam Tamofen Tamoxasta Tamoxifeni Citras Zemide

Deltakergruppe / Arm

Intervensjon / Behandling

Eksperimentell: Arm I (kjemoterapi og endokrin terapi)

Pasienter får et protokoll-godkjent kjemoterapiregime basert på pasientens og/eller legens preferanser. Pasienter får deretter en protokollgodkjent adjuvant endokrin terapi som omfatter tamoxifencitrat, en aromatasehemmer (anastrozol, letrozol eller exemestan), eller begge i 5-10 år i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

Annen: Laboratoriebiomarkøranalyse

Korrelative studier

Legemiddel: Letrozol

Gitt PO

Andre navn:

CGS 20267
Femara
Fempro

Legemiddel: Anastrozol

Gitt PO

Andre navn:

Arimidex
Anastrazol
ICI D1033
ICI-D1033
ZD-1033

Legemiddel: Eksemestan

Gitt PO

Andre navn:

Aromasin
FCE-24304

Annen: Livskvalitetsvurdering

Hjelpestudier (stengt fra 1.12.12)

Andre navn:

Livskvalitetsvurdering

Legemiddel: Systemisk kjemoterapi

Gitt IV

Legemiddel: Tamoxifen Citrate

Gitt PO

Andre navn:

Nolvadex
TAM
Soltamox
Apo-Tamox
Clonoxifen
Dignotamoxi
Ebefen
Emblon
Østroxyn
Fentamox
Gen-Tamoxifen
Genox
ICI 46.474
ICI-46474
Jenoxifen
Kessar
Ledertam
Lesporene
Nolgen
Noltam
Nolvadex-D
Nourytam
Novo-Tamoxifen
Novofen
Noxitem
Oestrifen
Oncotam
PMS-Tamoxifen
Tamax
Tamaxin
Tamifen
Tamizam
Tamofen
Tamoxasta
Tamoxifeni Citras
Zemide

Eksperimentell: Arm II (endokrin terapi)

Pasienter får en protokoll-godkjent endokrin terapi som omfatter tamoxifen citrat, en aromatasehemmer (anastrozol, letrozol eller exemestan), eller begge deler i 5-10 år i fravær av sykdomsprogresjon eller uakseptabel toksisitet.

Annen: Laboratoriebiomarkøranalyse

Korrelative studier

Legemiddel: Letrozol

Gitt PO

Andre navn:

CGS 20267
Femara
Fempro

Legemiddel: Anastrozol

Gitt PO

Andre navn:

Arimidex
Anastrazol
ICI D1033
ICI-D1033
ZD-1033

Legemiddel: Eksemestan

Gitt PO

Andre navn:

Aromasin
FCE-24304

Annen: Livskvalitetsvurdering

Hjelpestudier (stengt fra 1.12.12)

Andre navn:

Livskvalitetsvurdering

Legemiddel: Tamoxifen Citrate

Gitt PO

Andre navn:

Nolvadex
TAM
Soltamox
Apo-Tamox
Clonoxifen
Dignotamoxi
Ebefen
Emblon
Østroxyn
Fentamox
Gen-Tamoxifen
Genox
ICI 46.474
ICI-46474
Jenoxifen
Kessar
Ledertam
Lesporene
Nolgen
Noltam
Nolvadex-D
Nourytam
Novo-Tamoxifen
Novofen
Noxitem
Oestrifen
Oncotam
PMS-Tamoxifen
Tamax
Tamaxin
Tamifen
Tamizam
Tamofen
Tamoxasta
Tamoxifeni Citras
Zemide

Hva måler studien?

Primære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Invasiv sykdomsfri overlevelse (IDFS) Tidsramme: 5 år etter randomisering	Fra dato for randomisering (2. registrering) til dato for første invasive tilbakefall (lokalt, regionalt eller fjernt), andre invasive primærkreft (bryst eller ikke), eller død på grunn av en hvilken som helst årsak. Pasienter sist kjent for å være i live som ikke har opplevd tilbakefall eller andre primære kreft, sensureres ved siste kontaktdato. Dette er den STEEP-definisjonen av invasiv sykdomsfri overlevelse. Kaplan-Meier-estimater ble beregnet for 5-års IDFS-raten. På grunn av resultatene fra den tredje forhåndsspesifiserte interimanalysen, ble forhåndsspesifiserte separate analyser utført for alle utfall etter menopausal status (se statistisk analyse 2). NCI og data- og sikkerhetsovervåkingskomiteen anbefalte tidlig rapportering av dataene. Etter den primære analysen ble endringer i kvalifikasjonsstatus identifisert for tre deltakere, noe som gjorde populasjonen av kvalifiserte og evaluerbare deltakere forskjellig mellom rapporteringen av dette resultatet og både Deltakerflyt-delen og Uønskede hendelser-delen.	5 år etter randomisering

Sekundære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Antall deltakere med gr 3 til 5 uønskede hendelser som er relatert til studiemedisin Tidsramme: Behandlingsvarighet og oppfølging frem til død eller 3 år etter randomisering	Bare uønskede hendelser som er mulig, sannsynligvis eller definitivt relatert til studiemedikamentet er rapportert. Vurdert 6, 12, 24 og 36 måneder etter randomisering.	Behandlingsvarighet og oppfølging frem til død eller 3 år etter randomisering
Total overlevelse (OS) Tidsramme: 5,5 år etter randomisering	Tid fra dato for randomisering (2. registrering) til dato for død på grunn av en hvilken som helst årsak. Deltakere sist kjent for å være i live blir sensurert ved siste kontaktdato.	5,5 år etter randomisering
Fjern sykdomsfri overlevelse (DDFS) Tidsramme: 5,5 år etter randomisering	Tid fra dato for randomisering (2. registrering) til dato for tilbakefall av invasiv fjern sykdom, sekundær invasiv primærkreft (bryst eller ikke) eller død på grunn av en hvilken som helst årsak. Deltakere sist kjent for å være i live som ikke har opplevd fjernt tilbakefall, eller andre primære kreft, blir sensurert på deres siste kontaktdato. Dette sekundære resultatet krever at man fortsetter å følge pasienten etter lokalt tilbakefall for å fastslå påfølgende fjernt tilbakefall. Invasiv tilbakefall er definert som: opptreden av nye invasive lesjoner under eller etter protokollbehandling. Når det er mulig, bør residiv dokumenteres histologisk. Invasivt tilbakefall inkluderer lokalt, regionalt eller fjernt tilbakefall med en invasiv komponent. En ny diagnose av ipsilateral eller kontralateral DCIS uten en invasiv komponent anses ikke å være et residiv.	5,5 år etter randomisering
Lokalt sykdomsfritt intervall (LDFI) Tidsramme: Fra randomiseringsdato til maksimalt 5,5 år eller død	Tid fra dato for randomisering (2. registrering) til dato for invasiv lokal eller regional tilbakefall. Deltakere sist kjent for å være i live uten gjentakelse blir sensurert på deres siste kontaktdato. Deltakere med fjernt tilbakefall, annen primær kreft eller død blir sensurert på tidspunktet for den hendelsen. Invasiv tilbakefall er definert som: opptreden av nye invasive lesjoner under eller etter protokollbehandling. Når det er mulig, bør residiv dokumenteres histologisk. Invasivt tilbakefall inkluderer lokalt, regionalt eller fjernt tilbakefall med en invasiv komponent. En ny diagnose av ipsilateral eller kontralateral DCIS uten en invasiv komponent anses ikke å være et residiv.	Fra randomiseringsdato til maksimalt 5,5 år eller død
Deltaker-rapportert angst Tidsramme: 6 måneder etter randomisering	Angst blir evaluert med pasientrapportert resultatmålingsinformasjonssystem (PROMIS) Emotional Distress-Angst Short Form. Rå PROMIS-skårer kan skaleres om til T-skårer basert på en referansepopulasjon med en gjennomsnittlig poengsum på 50 og et standardavvik på 10. Høyere score reflekterer større angst. PROMIS Angstskåre ved 6-måneders tidspunkt vil bli sammenlignet mellom de to randomiserte studiearmene separat etter menopausal status.	6 måneder etter randomisering
Deltaker-rapportert helsestatus Tidsramme: 6 måneder etter randomisering	Vurdert ved hjelp av EuroQol-5D (EQ-5D), der deltakerne vurderer helsestatusen sin i fem ulike helserelaterte domener: mobilitet, egenomsorg, vanlige aktiviteter, smerte/ubehag og angst/depresjon. Råskårene kan konverteres til indeksskårer på en skala fra 0 til 1, hvor en høyere indeksskåre representerer bedre helse. EQ-5D-indeksskårer ved 6-måneders tidspunkt vil bli sammenlignet mellom de to randomiserte studiearmene separat etter menopausal status.	6 måneder etter randomisering

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

National Cancer Institute (NCI)

Etterforskere

Hovedetterforsker: Kevin M Kalinsky, SWOG Cancer Research Network

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Kalinsky K, Barlow WE, Gralow JR, Meric-Bernstam F, Albain KS, Hayes DF, Lin NU, Perez EA, Goldstein LJ, Chia SKL, Dhesy-Thind S, Rastogi P, Alba E, Delaloge S, Martin M, Kelly CM, Ruiz-Borrego M, Gil-Gil M, Arce-Salinas CH, Brain EGC, Lee ES, Pierga JY, Bermejo B, Ramos-Vazquez M, Jung KH, Ferrero JM, Schott AF, Shak S, Sharma P, Lew DL, Miao J, Tripathy D, Pusztai L, Hortobagyi GN. 21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer. N Engl J Med. 2021 Dec 16;385(25):2336-2347. doi: 10.1056/NEJMoa2108873. Epub 2021 Dec 1.

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Faktiske)

15. januar 2011

Primær fullføring (Faktiske)

1. februar 2023

Studiet fullført (Antatt)

1. oktober 2032

Datoer for studieregistrering

Først innsendt

6. januar 2011

Først innsendt som oppfylte QC-kriteriene

6. januar 2011

Først lagt ut (Antatt)

7. januar 2011

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

14. mai 2024

Siste oppdatering sendt inn som oppfylte QC-kriteriene

23. april 2024

Sist bekreftet

1. april 2024

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

NCI-2011-02623 (Registeridentifikator: CTRP (Clinical Trial Reporting Program))
U10CA032102 (U.S. NIH-stipend/kontrakt)
U10CA180888 (U.S. NIH-stipend/kontrakt)
U10CA180830 (U.S. NIH-stipend/kontrakt)
S12-03603
CDR0000692475
PS1007_A11PAMDREVW01
SWOG-S1007
S1007 (Annen identifikator: CTEP)

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

Kliniske studier på Duktalt brystkarsinom in situ

SamanTree Medical SA
St. Vincenz Krankenhaus GmbH, Paderborn

Fullført

Reoperasjonsfrekvens ved brystbevarende kirurgi ved bruk av Confocal Histolog®-skanner for intraoperativ marginvurdering (SHIELD)

Brystbevarende kirurgi | Brystkreft - Ductal Carcinoma in Situ (DCIS)

Tyskland
Washington University School of Medicine
LifeCell

Fullført

Studie for å vurdere perfusjon og pasienttilfredshet ved brystvorte-areola mastektomi med umiddelbar rekonstruksjon (NASSM)

Brystkreft | Profylaktisk mastektomi | Duktalt karsinom in situ - Kategori

Forente stater
Duke University
National Cancer Institute (NCI)

Fullført

Akseptabilitet av Active Monitoring (AM) som et behandlingsalternativ for Ductal Carcinoma in Situ (DCIS)

Duktalt karsinom in situ

Forente stater
Yale University
Patient-Centered Outcomes Research Institute

Fullført

Sammenlignende effektivitet av Sentinel Lymfeknutebiopsi for Ductal Carcinoma In Situ

Duktalt karsinom in situ

Forente stater
Sunnybrook Health Sciences Centre

Avsluttet

Diagnostisk studie av tidlig brystkreft ved bruk av ultralyd

Duktalt karsinom in situ

Canada
Indiana University
GlaxoSmithKline

Avsluttet

Lapatinib for behandling av duktalt karsinom in situ (DCIS) i brystet

Duktalt karsinom in situ

Forente stater
Windy Hill Medical, Inc.

Ukjent

Studie av intraduktalt karboplatin hos kvinner med duktalt karsinom in situ (DCIS)

Duktalt karsinom in situ

Forente stater
Ontario Clinical Oncology Group (OCOG)

Rekruttering

Prospektiv evaluering av brystbevarende kirurgi alene ved lavrisiko ductal carcinoma in situ (DCIS) (ELISA)

DCIS

Canada
Alliance Foundation Trials, LLC.
Patient-Centered Outcomes Research Institute; M.D. Anderson Cancer Center; Washington University School of Medicine og andre samarbeidspartnere

Aktiv, ikke rekrutterende

Sammenligne en operasjon med overvåking, med eller uten endokrin terapi (COMET) prøve for lavrisiko DCIS (COMET)

Duktalt karsinom in situ | DCIS

Forente stater
University of California, San Francisco
National Cancer Institute (NCI)

Fullført

Kontrastforbedret MR for karakterisering av duktal karsinom in situ (DCIS)

Brystkreft

Forente stater

Kliniske studier på Laboratoriebiomarkøranalyse

Fondation Lenval

Tilbaketrukket

Påvirkning av utmattelse på gangmønsteret hos pasienter med cerebral parese.

Cerebral parese

Frankrike
Liao Jian An

Rekruttering

Meridianenergiendringer hos pasienter med hode- og nakkekreft etter kjemoterapi eller strålebehandling

Hode- og nakkekreft

Taiwan
Progenity, Inc.

Fullført

Utvidet ikke-invasiv genomisk medisinsk vurdering: Enigma-studien

Downs syndrom | Aneuploidi | DiGeorge syndrom | Turners syndrom | Klinefelters syndrom | Kromosomsletting | Edwards syndrom | Patau syndrom

Forente stater
Tel-Aviv Sourasky Medical Center

Ukjent

Evaluering av evnen til CT-basert endelig elementanalyse (CTFEA) til å forutsi frakturer hos pasienter med metastaser: en randomisert kontrollert studie. (ZYCTFEA)

Benmetastaser | Ortopedisk lidelse | Benneoplasma i hoften (diagnose) | Proksimal femoral metafyseal abnormitet
IRCCS Eugenio Medea

Rekruttering

Biomarkørers baner for tidlig intervensjon hos søsken til barn med autismespekterforstyrrelse

Autismespektrumforstyrrelse | Tidlig intervensjon

Italia
Oregon Health and Science University
4DMedical

Påmelding etter invitasjon

Ventilasjonsubalanser ved mild til moderat kronisk obstruktiv lungesykdom (VAPOR)

Lungesykdommer | KOLS | Luftveissykdom | Dyspné

Forente stater
IRCCS Eugenio Medea

Rekruttering

Bekreft ytelsen i klinisk praksis til den oppslukende virtuelle virkelighetsplattformen GRAIL (Gait Real-time Analysis Interactive Lab)

Cerebral parese | Ervervet hjerneskade

Italia
Duke University

Tilbaketrukket

Point of Care-testing for å forbedre overvåking av LVAD-pasienter

Antikoagulasjons- og trombosepunkttest (AT-POCT)

Forente stater
Modarres Hospital

Fullført

Renal parenkymal kjernenålbiopsi

Komplikasjoner | Bildeveiledet biopsi | Nyre Glomerulus

Iran, den islamske republikken
University of California, Los Angeles

Fullført

Sikkerhet ved kroppssammensetningsanalyse hos hjertesviktpasienter med implanterbare cardioverter-defibrillatorer (ICD)

Hjertefeil | Overvekt

Forente stater

Tamoxifen Citrate, Letrozol, Anastrozol eller Exemestane med eller uten kjemoterapi ved behandling av pasienter med invasiv RxPONDER brystkreft

Studieoversikt

Status

Forhold

Intervensjon / Behandling

Detaljert beskrivelse

Studietype

Registrering (Faktiske)

Fase

Kontakter og plasseringer

Studiesteder

Deltakelseskriterier

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Tar imot friske frivillige

Beskrivelse

Studieplan

Hvordan er studiet utformet?

Designdetaljer

Antall våpen

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