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Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children

2012年1月23日 更新者:Bezatu Mengiste、Haramaya Unversity

Acceptability and Effectiveness of Household Water Chlorination in Reducing the Prevalence of Diarrhea Among Under Five Children in Eastern Ethiopia

The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water. This goal was adopted in large part because safe drinking water has been seen as critical to fighting diarrheal disease. Source protection is considered the main intervention area to achieve this goal. However, research worldwide that has shown that even drinking water which is safe at the source is subject to frequent and extensive fecal contamination during collection, storage and use in the home. This contamination is through the introduction of cups, dippers or hands, contamination by flies, cockroaches, and rats. Even piped water supplies of adequate microbial quality can pose infectious disease risks if they become contaminated due to unsanitary collection, storage conditions and practices within households.

To reduce this problem, point-of-use water treatment has been advocated as a means to substantially decrease the global burden of diarrhea and to contribute to the MDGs. However, research indicates that there are many unanswered questions around Household water treatment (HWT) that require small or medium scale epidemiological studies and randomized controlled trials, especially with regard to effectiveness, acceptability and identifying suitable target populations. Some of the most urgent questions to be resolved are:(1) How much of the currently cited disease reduction of HWT is due to bias? (2) What is the effect of HWT on nutritional status (weight gain and growth)?(3) At which populations should HWT be targeted? (4) Is it acceptable and sustainable in poor communities where the risk of diarrheal disease is high.

hypothesis: Do household water treatment with chlorine reduce diarrhea among underfive children? hypothesis: Do household water treatment with chlorine acceptable in the community?

研究概览

地位

完全的

条件

研究类型

介入性

注册 (实际的)

845

阶段

  • 阶段1

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • Eastern Hararage
      • Kersa、Eastern Hararage、埃塞俄比亚、235
        • Kersa district

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

1个月 至 4年 (孩子)

接受健康志愿者

不

有资格学习的性别

全部

描述

Inclusion Criteria:

  • All children under five years of age in the randomly selected clusters of Kersa district

Exclusion Criteria:

  • seriously sick children in the randomly selected clusters of Kersa district

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:预防
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:无(打开标签)

武器和干预

参与者组/臂
干预/治疗
实验性的:Household water treatment
household water treatment with 1.25% sodium hypochlorite
household water treatment with 1.25% sodium hypochlorite
其他名称:
  • 1.25% sodium hypochlorite
无干预:control
Usual practice (the use of "Jerrican" for water storage, which is considered as safe storage)

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
To assess the prevalence of diarrhea among under five children
大体时间:four months
weekly visit of the household for the presence of diarrhoea among underfive for four months in both the intervention and control groups
four months

次要结果测量

结果测量
措施说明
大体时间
To assess the weight gain among the intervention and control groups of under five children
大体时间:At the beginning and end of the study ( 4 months interval)
This is designed to assess whether there is weight gain (objective outcome) in children assigned to the intervention group compared to the control group. It is supplement to the prevalence of diarrhea which is subjective outcome for this study
At the beginning and end of the study ( 4 months interval)
Residual chlorine test
大体时间:four months
The use of the intervention (1.25% hypochlorite) is confirmed by the testing the residual chlorine weekly for for months from each household assigned in the intrevention group
four months

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Bezatu M Alemu, M.Sc、Assistant Professor

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2011年6月1日

初级完成 (实际的)

2011年10月1日

研究完成 (实际的)

2011年10月1日

研究注册日期

首次提交

2011年6月16日

首先提交符合 QC 标准的

2011年6月16日

首次发布 (估计)

2011年6月20日

研究记录更新

最后更新发布 (估计)

2012年1月24日

上次提交的符合 QC 标准的更新

2012年1月23日

最后验证

2012年1月1日

更多信息

与本研究相关的术语

其他研究编号

  • SGS13/15/11

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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