Effects of Transcranial Direct Current Stimulation on Cigarette Addiction
Effects of Transcranial Direct Current Stimulation of the Prefrontal Cortex on Cigarette Smoking
Tobacco addiction is treatable with behavioral and pharmacological means, but results are often less than optimal. Transcranial direct current stimulation is a new non-invasive technique that applies weak electrical currents through the skull and has been shown to alter the excitability of certain brain areas. It is currently being tried in disorders where there is abnormal brain excitability, such as epilepsy and depression. A few studies have also been able to diminish drug craving, suggesting that brain excitability might also be altered in drug addiction.
This study aims at non-invasively changing the excitability of certain brain areas-a procedure called neuromodulation- in order to help smokers quit smoking more easily.
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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DF
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Brasília、DF、巴西、71910-900
- Hospital Universitário de Brasília- HUB
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- smokers
Exclusion Criteria:
- use of psychoactive drugs
- age above 70
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
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实验性的：Transcranial Direct Current Stimulation
These subjects will receive real transcranial direct current stimulation.
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Transcranial Direct Current Stimulation (tDCS) is a procedure that uses a small battery-driven unit to deliver weak electrical currents (1-2 mA) through the intact scalp.
The procedure is painless and is thought to modulate the excitability of the underlying cerebral tissue for hours or days after sessions.
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安慰剂比较：Sham tDCS
These subjects will receive sham transcranial direct current stimulation (placebo)
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Transcranial Direct Current Stimulation (tDCS) is a procedure that uses a small battery-driven unit to deliver weak electrical currents (1-2 mA) through the intact scalp. The procedure is painless and is thought to modulate the excitability of the underlying cerebral tissue for hours or days after sessions. In the placebo group the current will be off. |
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
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Change in Visual Analogue Scale of Cigarette Craving
大体时间：Before and 7 days after treatment
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Before and 7 days after treatment
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次要结果测量
结果测量 |
大体时间 |
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Change in Visual Analogue Scale of Motivation to Quit Smoking
大体时间：Before and 7 days after intervention
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Before and 7 days after intervention
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合作者和调查者
调查人员
- 首席研究员：Raphael Boechat-Barros, MD、University of Brasilia
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.