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Monitoring of Visual Axis Opacification Under Non-clinical Settings

2015年12月7日 更新者:Haotian Lin、Sun Yat-sen University

Self-monitoring of Visual Axis Opacification (VAO) Under Non-clinical Settings in China

The incidence rate of postoperative capsular opacification (PCO) in children after cataract surgery is reported to be as high as 100%, while timely Nd: YAG laser posterior capsulotomy is effective to treat visual axis opacification (VAO) caused by PCO. Therefore, long-term follow-up, timely diagnosis and treatment is important to improve patient's outcome.

The major and central part of lens is easy to be observed through a dilated pupil. Especially, opacification in the lens and/or lens capsule is distinctive showing as "white" on the "black" background. The characteristic features of the disease and advances in photographic technique with mobile phone make it possible for patients and/or their guardians to monitor the progress of cataract or PCO with mobile application in a "self-help" manner under non-clinical settings.

研究概览

地位

未知

条件

详细说明

The incidence rate of postoperative capsular opacification (PCO) in children after cataract surgery is reported to be as high as 100%, while timely Nd: YAG laser posterior capsulotomy is effective to treat visual axis opacification (VAO) caused by PCO. Therefore, long-term follow-up, timely diagnosis and treatment is important to improve patient's outcome.

The major and central part of lens is easy to be observed through a dilated pupil. Especially, opacification in the lens and/or lens capsule is distinctive showing as "white" on the "black" background. The characteristic features of the disease and advances in photographic technique with mobile phone make it possible for patients and/or their guardians to monitor the progress of cataract or PCO with mobile application in a "self-help" manner under non-clinical settings. In this way, patients and/or guardians could adjust the time of return to clinical follow-up visit accordingly. Furthermore, standardized and analyzed pictures could be sent to clinicians for remote diagnosis when necessary.

The investigators developed a mobile phone application LenZOC. The investigators aimed to assess whether mobile phone application for parents of children with cataracts would improve their adherence with follow-up and increase rates of timely detection and management of treatable conditions such as posterior capsular opacification (PCO).

研究类型

介入性

注册 (预期的)

1400

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • Guangdong
      • Guangzhou、Guangdong、中国、510060
        • Zhognshan Ophthalmic Center, Sun Yat-sen University

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

不超过 18年 (孩子、成人)

接受健康志愿者

不

有资格学习的性别

全部

描述

Inclusion Criteria:

  • Children after cataract surgery for more than 1 year without any postoperative complications
  • Without other ocular abnormality
  • Parents owned a smart mobile phone that meets the requirements for installation of the LenZOC
  • Written informed consents provided

Exclusion Criteria:

  • Intraocular pressure >21 mmHg
  • Pre-existing ocular diseases including but not restricted to:

Glucoma Micro-cornea Micro-ophthalmic Diseases of post-segment that might lead to VAO

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:无(打开标签)

武器和干预

参与者组/臂
干预/治疗
实验性的:telemedicine group
Congenital cataract patients use telemedicine to pursue and adjust the time of follow-up under non-clinical settings
The transparency of the visual axial at the anterior segment is observed through a dilated pupil. Image of the eye of a patient taken with LenZOC is calibrated with a standardized white and black bar adhered to the patient's eyelid. Calibrated images are dimmed as graysalegrayscale. The intensity and progress of visual axial opacification (VAO) is quantified as absolute area and relative area (calculated as: absolute area of VAO/ absolute area of dilated pupil).
无干预:non-telemedicine group
Congenital cataract patients pursue and adjust the time of follow-up through outpatient visit in the hospital

研究衡量的是什么?

主要结果指标

结果测量
大体时间
Times of follow-ups for each participant
大体时间:up to one year
up to one year

次要结果测量

结果测量
大体时间
Best corrected visual acuity
大体时间:up to 24 weeks
up to 24 weeks

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Haotian Lin, M.D. Ph.D.、Zhongshan Ophthalmic Center, Sun Yat-sen University
  • 学习椅:Yizhi Liu, M.D. Ph.D.、Zhongshan Ophthalmic Center, Sun Yat-sen University

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2016年1月1日

初级完成 (预期的)

2018年1月1日

研究完成 (预期的)

2018年1月1日

研究注册日期

首次提交

2015年12月7日

首先提交符合 QC 标准的

2015年12月7日

首次发布 (估计)

2015年12月10日

研究记录更新

最后更新发布 (估计)

2015年12月10日

上次提交的符合 QC 标准的更新

2015年12月7日

最后验证

2015年12月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • CCPMOH2010-China10

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