A Danish Nationwide Longitudinal Study on Prevalence of Periodontitis and Its Co-morbidities (PlanPerioMed)
A Danish Nationwide Longitudinal Registered Based Study on Prevalence, Treatment Patterns and Disease Trajectories of Periodontitis and Co-morbidities 'PlanPerioMed'
The project (PlanPerioMed) is a register-based study evaluating the associations and patterns of health care delivery between periodontitis and medical diseases using data from the Danish dental record system Dentalsuite (Plandent A/S) and national Danish health care registries with three overall hypotheses/ aims:
- Determine the extent to which periodontitis in registry data is associated with more odontological treatment services and treatment frequency.
- Determine if patients with systemic diseases attend dentists more frequently and receive more treatment services per patient than the population without these diseases.
- Determine to which extent periodontitis and received periodontal treatment affects the risk of medical diseases.
The study will focus on association and trajectories of periodontitis and its treatment with three medical diseases, namely, Type 2 Diabetes Mellitus (Type 2 DM), Cardiovascular Diseases (CVD) and Rheumatoid Arthritis (RA). The dataset consists of approximately 4,000,000 people aged between 18 and 99 years attending private practice in Denmark. The results from PlanPerioMed study are likely to have ramifications for treatment guidelines for other periodontitis comorbidities, e.g. CVD and DM, and will thereby improve the quality of life for a wide range of patients and reduce long-term societal health care expenses related to periodontitis and its comorbidities.
研究概览
研究类型
注册 (预期的)
联系人和位置
学习联系方式
- 姓名:Christian Damgaard
- 电话号码:+4525323832
- 邮箱:chrd@sund.ku.dk
研究联系人备份
- 姓名:Simranjit Kaur
- 电话号码:+4531545565
- 邮箱:simranjit.kaur@sund.ku.dk
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Subjects with clinical registrations of DMFT, periodontal status and corresponding treatment codes
- Self-reported systemic diseases including Diabetes Mellitus Type 2, Cardiovascular Diseases and Rheumatoid Arthritis
- Subjects with Clinical Attachment Loss>=3mm, Probing Depth >= 3mm and bleeding on probing (as defined by World Workshop 2017- criteria for periodontitis) in clinical examination will be included in the study population.
Exclusion Criteria:
- Subjects with more than 32 teeth
- Subjects with no clinical registrations
学习计划
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Treatment frequency and type of treatment services
大体时间:25 years
|
Number of treatment and odontological treatment services due to periodontitis
|
25 years
|
|
Treatment frequency and type of treatment services among patients with medical diseases
大体时间:25 years
|
Number of treatment and odontological treatment services among patients with medical diseases due to periodontitis
|
25 years
|
|
Effect on medical diseases
大体时间:25 years
|
Risk of medical diseases based on periodontal disease extent and received periodontal treatment
|
25 years
|
合作者和调查者
出版物和有用的链接
一般刊物
- Kongstad J, Ekstrand K, Qvist V, Christensen LB, Cortsen B, Gronbaek M, Holm-Pedersen P, Holmstrup P, Bardow A, Twetman S, Fiehn NE. Findings from the oral health study of the Danish Health Examination Survey 2007-2008. Acta Odontol Scand. 2013 Nov;71(6):1560-9. doi: 10.3109/00016357.2013.776701. Epub 2013 Apr 29.
- Kongstad J, Enevold C, Christensen LB, Fiehn NE, Holmstrup P. Impact of Periodontitis Case Criteria: A Cross-Sectional Study of Lifestyle. J Periodontol. 2017 Jun;88(6):602-609. doi: 10.1902/jop.2017.160426. Epub 2017 Jan 27.
- Hansen GM, Egeberg A, Holmstrup P, Hansen PR. Relation of Periodontitis to Risk of Cardiovascular and All-Cause Mortality (from a Danish Nationwide Cohort Study). Am J Cardiol. 2016 Aug 15;118(4):489-93. doi: 10.1016/j.amjcard.2016.05.036. Epub 2016 May 30.
- Holmstrup P, Damgaard C, Olsen I, Klinge B, Flyvbjerg A, Nielsen CH, Hansen PR. Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician. J Oral Microbiol. 2017 Jun 14;9(1):1332710. doi: 10.1080/20002297.2017.1332710. eCollection 2017.
- Hansen PR, Holmstrup P. Cardiovascular Diseases and Periodontitis. Adv Exp Med Biol. 2022;1373:261-280. doi: 10.1007/978-3-030-96881-6_14.
- Joseph R, Rajappan S, Nath SG, Paul BJ. Association between chronic periodontitis and rheumatoid arthritis: a hospital-based case-control study. Rheumatol Int. 2013 Jan;33(1):103-9. doi: 10.1007/s00296-011-2284-1. Epub 2012 Jan 7.
有用的网址
研究记录日期
研究主要日期
学习开始 (预期的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
关键字
- Periodontal Diseases, Periodontal Index, Periodontal Bone Loss, Periodontal Attachment Loss, Probing Depth, Bleeding on Probing, Clinical Attachment Loss
- Diabetes Mellitus 2, DM type 2, Non-insulin dependent diabetes mellitus, Uncontrolled diabetes mellitus type 2, Increased blood glucose level
- CVD, Cardiovascular risk, Heart disease, Heart disease risk factors
- Smoking status, Socio-economic status, Register based, Longitudinal study, Danish nationwide study, systemic diseases
其他研究编号
- 522-0018/22-3800 (其他赠款/资助编号:Plandent A/S)
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)?
药物和器械信息、研究文件
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研究美国 FDA 监管的设备产品
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