Internuclear Ophthalmoplegia and Multiple Sclerosis: a Multicenter Retrospective Study (INO&MS)
Internuclear ophthalmoplegia is a symptom frequently associated with multiple sclerosis (MS), although other etiologies are possible. Some patients do not meet the diagnostic criteria for MS at the time of the internuclear ophthalmoplegia episode but subsequently convert to MS. Studying this specific clinical situation may help enable earlier diagnosis of MS.
The objective is to analyze the proportion of patients with isolated internuclear ophthalmoplegia who convert to multiple sclerosis and to identify factors associated with this conversion.
The study hypothesis is that the presence of internuclear ophthalmoplegia is highly suggestive of multiple sclerosis, particularly when cerebrospinal fluid-specific oligoclonal bands are present.
研究概览
研究类型
注册 (估计的)
联系人和位置
学习联系方式
- 姓名：Kévin BIGAUT
- 电话号码：+33 3 88 12 60 96
- 邮箱：kevin.bigaut@chru-strasbourg.fr
研究联系人备份
- 姓名：Sebille COLIN
- 电话号码：+33 3 88 11 52 17
- 邮箱：sebille.colin@chru-strasbourg.fr
学习地点
-
-
-
Strasbourg、法国、67 200
- Les Hôpitaux Universitaires
-
接触：
- Kévin BIGAUT
- 邮箱：kevin.bigaut@chru-strasbourg.fr
-
-
参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
取样方法
研究人群
描述
Inclusion criteria:
- Patients with internuclear ophthalmoplegia listed as a primary or associated diagnosis
- Patients hospitalized in a neurology department
Exclusion criteria:
- Patients under 18 years of age
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
|---|
|
Internuclear ophthalmoplegia
This is a retrospective cohort study involving patients who have experienced internuclear ophthalmoplegia.
For each patient, it is determined whether a diagnosis of multiple sclerosis was established or not.
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Analyze the proportion of patients with isolated internuclear ophthalmoplegia who convert to multiple sclerosis.
大体时间：1 year
|
Proportion of patients with isolated internuclear ophthalmoplegia who converted to multiple sclerosis during follow-up.
|
1 year
|
合作者和调查者
调查人员
- 首席研究员：Kévin BIGAUT、Hopitaux Universitaires de Strasbourg
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.