此页面是自动翻译的,不保证翻译的准确性。请参阅 英文版 对于源文本。

Chronotype Alignment and Time Perception

2026年6月29日 更新者:Dr YU Cehao、The Hong Kong Polytechnic University

Circadian Match and Mismatch Effects on Temporal Cognition in Morning- and Evening-Type Adults

People differ in chronotype - whether they function best in the morning ("larks") or the evening ("owls"). This study asks whether the match or mismatch between a person's chronotype and the time of day at which they are tested changes how they perceive time.

Healthy morning-type and evening-type adults at three sites (Aarhus, Denmark; Changzhou, China; and Hong Kong) complete the same battery of perception and cognition tasks twice - once in the early morning (about 08:00) and once late in the evening (about 22:00), in counterbalanced order. The primary outcome is the accuracy (signed bias) of time-perception judgements; the key comparison is the interaction between chronotype and time of day (the "synchrony effect").

Secondary measures include timing precision, the subjective passage of time, sleepiness, mood, colour perception (with and without blue-blocking glasses) and perceptual decision-making. By testing the same protocol across three cultures and latitudes, the study examines whether circadian match/mismatch effects on temporal cognition generalise across populations.

研究概览

详细说明

Background and rationale: Time perception is shaped by attention and physiological arousal, both of which follow a circadian rhythm that differs systematically between morning-type and evening-type individuals. The "synchrony effect" holds that performance is optimal when testing occurs at a person's circadian-preferred time. Whether this match/mismatch alters the perceived speed and precision of an internal clock, and whether any such effect generalises across cultures and latitudes, is not well established.

Design: a 2 (chronotype: morning-type vs evening-type; between-subjects) x 2 (session time: morning about 08:00 vs evening about 22:00; within-subjects, counterbalanced) mixed design, replicated at three sites. "Match" = tested at the circadian-preferred time; "mismatch" = tested at the non-preferred time. Site is included as an additional factor for generalisability.

Procedure: volunteers are screened online (Morningness-Eveningness Questionnaire to classify chronotype, with intermediate types excluded; Munich ChronoType Questionnaire; Pittsburgh Sleep Quality Index; demographics; colour-vision and health checks) and keep a 7-day sleep diary. Eligible participants attend two laboratory sessions and complete an identical battery each time: time-perception tasks (interval production/estimation, duration discrimination, passage-of-time judgement), state measures (sleepiness, mood, arousal), colour tasks (unique-hue settings with and without blue-blocking glasses; an ambiguous-colour image), a perceptual conformity task, and a vigilance task.

Primary hypothesis: a chronotype-by-time-of-day interaction on time-perception bias. Analysis uses linear mixed-effects models (participant as a random effect; chronotype, session time, their interaction, and site as fixed effects), with false-discovery-rate correction across secondary outcomes. Session order is counterbalanced to separate time-of-day from practice and order effects.

研究类型

介入性

注册 (估计的)

240

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习联系方式

学习地点

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

是的

描述

Inclusion Criteria:

  • Healthy adult, 18-40 years
  • Clear morning-type or evening-type on the Morningness-Eveningness Questionnaire (MEQ-SA); intermediate types excluded (state exact cut-offs, e.g. evening-type 41 or below, morning-type 59 or above)
  • Normal or corrected-to-normal visual acuity
  • Normal colour vision (e.g. Ishihara screening)
  • Fluent in the testing-site language (Danish, Chinese, or English)
  • Able to attend both an early-morning (about 08:00) and a late-evening (about 22:00) session

Exclusion Criteria:

  • Intermediate chronotype (MEQ in the middle band)
  • Night or rotating shift work in the past 3 months, or recent trans-meridian travel (more than 2 time zones in the past 4 weeks)
  • Diagnosed sleep disorder (e.g. insomnia, sleep apnoea)
  • Current psychiatric or neurological disorder
  • Use of sleep medication or psychoactive or CNS-active drugs
  • Colour-vision deficiency
  • Substance-use disorder

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:基础科学
  • 分配:随机化
  • 介入模型:交叉作业
  • 屏蔽:无(打开标签)

武器和干预

参与者组/臂
干预/治疗
实验性的:Morning-first sequence
Participants complete the Morning test session (about 08:00) first, then the Evening test session (about 22:00). Both sessions use the identical perception and cognition battery; session order is counterbalanced across participants.
Full perception and cognition battery administered shortly after habitual wake (about 08:00): time-perception tasks (interval production/estimation, duration discrimination, passage-of-time judgement), state measures (sleepiness, mood, arousal), colour tasks, a perceptual conformity task, and a vigilance task.
The identical battery administered late in the evening (about 22:00), enabling within-participant comparison of the same measures at the two times of day.
实验性的:Evening-first sequence
Participants complete the Evening test session (about 22:00) first, then the Morning test session (about 08:00). Both sessions use the identical perception and cognition battery; session order is counterbalanced across participants.
Full perception and cognition battery administered shortly after habitual wake (about 08:00): time-perception tasks (interval production/estimation, duration discrimination, passage-of-time judgement), state measures (sleepiness, mood, arousal), colour tasks, a perceptual conformity task, and a vigilance task.
The identical battery administered late in the evening (about 22:00), enabling within-participant comparison of the same measures at the two times of day.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Time-perception bias measured by the two-alternative forced-choice duration-comparison point of subjective equality
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Participants complete a two-alternative forced-choice duration-comparison task. On each trial, they judge whether a comparison interval is shorter or longer than a standard interval. A psychometric function is fitted to each participant's responses to estimate the point of subjective equality, defined as the comparison duration judged longer than the standard on 50% of trials. Time-perception bias is calculated as signed percentage error: ((point of subjective equality - standard duration) / standard duration) × 100. Positive values indicate a point of subjective equality above the standard duration; negative values indicate a point of subjective equality below the standard duration. The primary comparison is the chronotype-by-session-time interaction, testing whether time-perception bias differs between circadian match and mismatch sessions.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.

次要结果测量

结果测量
措施说明
大体时间
Temporal precision measured by the two-alternative forced-choice duration-discrimination Weber fraction
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Participants complete a two-alternative forced-choice duration-discrimination task using an adaptive staircase procedure. On each trial, they judge whether a comparison interval is shorter or longer than a standard interval. A psychometric function is fitted to estimate the just-noticeable difference, defined as the smallest duration difference required for reliable discrimination. Temporal precision is calculated as the Weber fraction: just-noticeable difference divided by the standard duration. Lower Weber-fraction values indicate better temporal precision, whereas higher values indicate poorer temporal precision.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Subjective passage of time measured by a passage-of-time rating scale
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Participants rate their subjective passage of time during the laboratory session using a passage-of-time rating scale. The scale ranges from 1 to 7, where 1 indicates that time passed very slowly and 7 indicates that time passed very quickly. Higher scores indicate a faster subjective passage of time, whereas lower scores indicate a slower subjective passage of time.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Subjective sleepiness measured by the Karolinska Sleepiness Scale
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Subjective sleepiness is assessed using the Karolinska Sleepiness Scale, a 9-point self-report scale ranging from 1 to 9. A score of 1 indicates very alert, and a score of 9 indicates very sleepy or fighting sleep. Higher scores indicate greater subjective sleepiness. The scale is administered before and after the laboratory task battery in each session; the outcome will be analysed as session-level subjective sleepiness, with pre- and post-battery ratings used to characterise changes across the session.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Mood measured by the Multidimensional Mood Questionnaire
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Mood is assessed using the Multidimensional Mood Questionnaire. The questionnaire provides three bipolar mood dimensions: good-bad mood, awake-tired mood, and calm-nervous mood. Each dimension is scored from 4 to 20. Higher scores indicate a more positive mood state: better mood on the good-bad dimension, greater wakefulness on the awake-tired dimension, and greater calmness on the calm-nervous dimension.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Unique-hue settings measured as hue angle in the Commission Internationale de l'Éclairage Colour Appearance Model 2016 (CIECAM16)
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Participants complete a unique-hue adjustment task for unique yellow, blue, green, and red. For each unique hue, the selected colour is converted to a hue angle in the Commission Internationale de l'Éclairage Colour Appearance Model 2016 (CIECAM16). Hue angle is measured in degrees (0°-360°), representing the location of the selected colour around the hue circle. The task is completed both with and without blue-blocking glasses. Hue angle is an angular colour-coordinate measure; higher or lower values do not indicate a better or worse outcome but indicate a shift in the perceived unique-hue setting.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Ambiguous-colour image perception measured by forced-choice categorisation of the dress image
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Participants view the ambiguous dress image and complete a forced-choice categorisation task. They indicate whether they perceive the image as white/gold or blue/black. The outcome is the categorical response to the image, recorded separately with and without blue-blocking glasses. This measure indexes individual differences in colour-perception interpretation and illuminant assumptions, and whether the perceived category shifts with reduced short-wavelength input or time of day. This is a categorical perceptual outcome; higher or lower values do not indicate a better or worse outcome.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Perceptual conformity measured by change in perceptual judgement after social-response exposure
大体时间:Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.
Participants complete a perceptual judgement task before and after exposure to others' responses. Perceptual conformity is measured as the change in the participant's judgement from the initial response to the post-exposure response. Larger absolute change scores indicate greater susceptibility to social influence on perception. Positive or negative scores indicate the direction of change relative to the participant's initial judgement or relative to the displayed social response, depending on the specific perceptual judgement scale used.
Each of two laboratory sessions, morning about 08:00 and evening about 22:00, completed within about 2 weeks.

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2025年9月1日

初级完成 (估计的)

2028年6月30日

研究完成 (估计的)

2028年6月30日

研究注册日期

首次提交

2026年6月22日

首先提交符合 QC 标准的

2026年6月29日

首次发布 (实际的)

2026年6月30日

研究记录更新

最后更新发布 (实际的)

2026年6月30日

上次提交的符合 QC 标准的更新

2026年6月29日

最后验证

2026年6月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

是的

IPD 计划说明

De-identified individual participant data underlying the published results, together with the study protocol, statistical analysis plan, and analysis code, will be made openly available via the Open Science Framework (OSF).

IPD 共享时间框架

Beginning after publication of the primary results, with no planned end date.

IPD 共享访问标准

Open access via the Open Science Framework; no application required.

IPD 共享支持信息类型

  • 研究方案
  • 树液
  • 分析代码

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

订阅