此页面是自动翻译的,不保证翻译的准确性。请参阅 英文版 对于源文本。

Efficacy of Seated Exercise on Functional Capacity and Quality of Life in Patients With Leukemia During Chemotherapy Cycles

2026年8月13日 更新者:Aya salah el din fouad rostom、Suez University
This study aims to evaluate the efficacy of seated exercise on functional capacity and quality of life in patients with leukemia during chemotherapy cycles Participants will receive efficacy of seated exercise on functional capacity and quality of life in patients with leukemia during chemotherapy cycles over a defined period. Outcomes will be assessed using Pulmonary function test, 6 min walk test and FACT- G questionnaire to determine improvements in quality of life in cancer patient rehabilitation special to diagnosed with leukemia.

研究概览

地位

尚未招聘

条件

详细说明

Cancer is a major public health that gives an economical burden on the patient and government. The incidence of different types of cell tumors are increasing nowadays. Although chemotherapy is given to kill cancer cells, it also damage normal cells and cause significant side effects while others may have more. Some CT side effects can be severe enough to require hospitalization effects. CT affects patients functional capacity and quality of life next to the cancer it self. This study is designed as randomized controlled trial to assess the impact of seated exercise on functional capacity and quality of life in patient with leukemia during chemotherapy cycles. participants will be recruited from Hematology unit, Department of General Internal Medicine, Benha University Hospitals .

The intervention protocol includes a-30 minutes seated exercise program three times a week with at least a one- day break between sessions for four weeks for the treatment group. Outcome measures will include maximum voluntary ventilation, 6 min walk test distance and FACT-G questionnaire before and after the exercise program. The program includes a five- minute warmup, 20 minutes of moderate-intensity repetitive motion exercise and a five- minute cool down.

Ethical considerations:

This study has been reviewed and approved by the Ethical Committee of Benha university. Written informed consent will be obtained from all participants or their legal guardians prior to treatment.

研究类型

介入性

注册 (估计的)

30

阶段

  • 不适用

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

不

描述

Inclusion Criteria:

  1. Male patients with age ranges from 30 to 40 years.
  2. All patients in this study will be on chemotherapy from at least one cycle as a treatment of leukemia.
  3. All patients will be hemodynamically stable.
  4. Patients are ambulant.

Exclusion Criteria:

  1. Lung cancer
  2. History of any pulmonary disease.
  3. Metastasis of lung , ribs and mediastinal structure.
  4. Pulmonary pathology (e.g. acute respiratory distress syndrome, or exacerbation of chronic obstructive pulmonary disease).
  5. Ruptured eardrum or any other condition of the ear.
  6. Severe bronchospasm.
  7. High peak air way pressure (barotraumas).
  8. patients with marked elevated left ventricular end- diastolic volume and pressure.
  9. patients with worsening haert failure signs and symptoms.

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:单身的

武器和干预

参与者组/臂
干预/治疗
实验性的:Seated exercise group

Participants in the intervention group will perform a structured seated exercise program during their chemotherapy cycles. The exercise program will consist of supervised, individualized seated exercises designed to improve functional capacity and quality of life. The exercise sessions will be performed according to the study protocol throughout the intervention period.

Each session will consist of a five-minute warm up, 20 minutes of moderate intensity repetitive motion exercises, and a five -minute cool-down. Functional outcomes will be assessed before and after the exercise program. including maximum voluntary ventilation , six-minute walk test distance, and FACT- G quesionnaire.

无干预:control group
control group will receive usual care/ standard advices

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
change in functional capacity
大体时间:Baseline and after 4 weeks of intervention
Functional capacity will be assessed by the six-minute walk test (6MWT) distance before and after the four week seated exercise programe.
Baseline and after 4 weeks of intervention
change in quality of life
大体时间:Baseline and after 4 weeks of intervention
Quality of life will be assessed using the Functional Assessment of Cancer Therapy General (FACT-G) questionnaire before and after week seated exercise programe. the total FACT-G score ranges from 0 to 108, with higher scores indicating better quality of life
Baseline and after 4 weeks of intervention

次要结果测量

结果测量
措施说明
大体时间
Change in Maximum Voluntary Ventilation (MVV)
大体时间:Baseline and after 4 weeks of intervention
Change in Maximum Voluntary Ventilation (MVV) will be assessed before and after the four week seated exercise program
Baseline and after 4 weeks of intervention

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (估计的)

2026年8月1日

初级完成 (估计的)

2026年11月1日

研究完成 (估计的)

2026年12月1日

研究注册日期

首次提交

2026年7月28日

首先提交符合 QC 标准的

2026年7月28日

首次发布 (实际的)

2026年7月31日

研究记录更新

最后更新发布 (实际的)

2026年8月17日

上次提交的符合 QC 标准的更新

2026年8月13日

最后验证

2026年8月1日

更多信息

与本研究相关的术语

其他研究编号

  • seated exercises in leukemia

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

订阅