Interpretation Bias Modification Training for Social Anxiety Disorder (SAD)
2026年8月5日 更新者：University of Wisconsin, Milwaukee
Computerized Interpretation Bias Modification Training for Social Anxiety Disorder
The overall goal of the current study is to develop and evaluate a computerized interpretation bias modification (IBM) training for treating social anxiety disorder (SAD). A key focus is placed on enhancing accessibility and efficacy of IBM for SAD by delivering it through a mobile platform, with three specific aims outlined.
First, the current study aims to examine the efficacy of the IBM training in reducing social anxiety symptoms by comparing the pre-, post-, and follow-up assessments of the IBM group with a control group.
Second, the current study aims to examine the effect of IBM on reducing participants' daily social anxiety symptoms using daily diary methodology.
Third, the investigators also aim to evaluate the feasibility and acceptability of the IBM training. The investigators expect that at least 70% of participants will complete 4 or more of the six training sessions.
研究概览
地位
完全的
条件
研究类型
介入性
注册 (实际的)
50
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
Wisconsin
-
Milwaukee、Wisconsin、美国、53211
- University of Wisconsin-Milwaukee
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
接受健康志愿者
不
描述
Inclusion Criteria:
- Diagnosis of SAD based on the DIAMOND screening interview
- Moderate or severe symptoms of SAD as assessed by the Liebowitz Social Anxiety Scale (LSAS score of >= 30)
- Ages 18-60
- English as a primary language
- Possession of a mobile device for access to training and text message for daily diary
Exclusion Criteria:
- Self-report visual impairment that cannot be adjusted and will prevent them from clearly recognizing words and pictures on mobile screen
- Self-reported history of a bipolar disorder or psychotic disorder as measured by Diagnostic History Scale
- Current psychotherapy for SAD
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Cognitive Bias Modification for Interpretation Bias (CBM-I)
CBM-I is designed to modify negative interpretation bias, a core cognitive characteristic of social anxiety disorder.
During the training, participants will complete sentence fragments by filling in missing letters, guiding them to interpret ambiguous social scenarios in a benign way.
Participants will complete the training three times per week for two weeks.
|
Interpretation Bias Modification Training aims to help participants interpret ambiguous social scenarios in a benign way, with the goal of reducing social anxiety symptoms.
Individuals with social anxiety disorder tend to interpret ambiguous social situations negatively or catastrophize mildly negative events.
This intervention targets this core cognitive characteristic by repeatedly training more adaptive interpretation.
Cognitive training is delivered through mobile devices, increasing accessibility and cost-effectiveness while allowing participants to complete the intervention remotely.
|
|
有源比较器：Stress Management Psychoeducation (SMP) Group
The Stress Management Psychoeducation (SMP) group will also receive a cognitive training intervention involving the completion of sentence fragments by filling in missing letters.
However, the training content will focus on stress management strategies, such as relaxation techniques and organizational skills, rather than interpretation bias modification.
Participants in the SMP group will also complete the training three times per week for two weeks.
|
Stress Management Psychoeducation (SMP) is used as a credible comparison condition to evaluate whether CBM-I has specific therapeutic effects on reducing social anxiety symptoms.
The SMP condition follows the same training format as CBM-I, in which participants complete fragmented sentences by filling in missing letters.
However, the training content focuses on stress management strategies rather than modifying maladaptive interpretations of ambiguous social situations.
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Brief Fear of Negative Evaluation (BFNE)
大体时间：Pre-training (baseline); Post-training (approximately 1-2 days after completion of the 2-week intervention); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
The BFNE is a 12-item questionnaire, evaluating the level of apprehension and distress about expected negative evaluation.
The BFNE was used to assess the cognitive symptoms of social anxiety disorder.
|
Pre-training (baseline); Post-training (approximately 1-2 days after completion of the 2-week intervention); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
|
Liebowitz Social Anxiety Scale- Self-report Version (LSAS-SR)
大体时间：Pre-training (baseline); Post-training (approximately 1-2 days after completion of the 2-week intervention); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
The LSAS-SR is a 24-item scale that assesses the severity of social anxiety symptoms across two subscales: the level of anxiety (emotional reaction) and the level of avoidance (behavioral reaction).
In the current study, the two subscales will be analyzed separately to evaluate the effects of the intervention on the emotional and behavioral symptoms of social anxiety.
|
Pre-training (baseline); Post-training (approximately 1-2 days after completion of the 2-week intervention); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
|
Diagnostic Interview for Anxiety, Mood, and OCD and Related Neuropsychiatric Disorders (DIAMOND)
大体时间：Pre-training (baseline); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
DIAMOND is a semi-structured diagnostic interview to assess DSM-5 psychiatric disorders and has demonstrated good reliability and validity.
For the current study, only the social anxiety disorder module was administered at pre-training and follow-up assessments.
|
Pre-training (baseline); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Word Sentence Association Paradigm (WSAP)
大体时间：Pre-training (baseline); Post-training (approximately 1-2 days after completion of the 2-week intervention); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
The WSAP task was used to evaluate interpretation bias in response to ambiguous situations.
During the task, participants indicate whether a presented word (either negative or benign) is related or unrelated to a subsequently presented ambiguous sentence.
The scenarios included both social and general situations.
The percentage of endorsement responses was calculated separately for each trial type: social-threat, social-benign, general-threat, and general benign.
|
Pre-training (baseline); Post-training (approximately 1-2 days after completion of the 2-week intervention); 2-week follow-up (2 weeks after completion of the 2-week intervention)
|
|
Daily Diary
大体时间：2 weeks of training period
|
Daily diary was used to evaluate participants' daily social interactions and changes in social anxiety symptoms.
Participants in both groups received a text message to complete the daily diary survey each evening over the 2-week period of training.
The survey first asked participants to report the social interactions they had experienced that day, followed by questions assessing anxiety, avoidance, negative self-perception, fear of negative judgment, and satisfaction related to the most stressful social interaction.
|
2 weeks of training period
|
|
Credibility and Expectancy Questionnaire (CEQ)
大体时间：After the 1st training session
|
The CEQ is a self-report measure that assesses participants' perceptions of the credibility of an intervention their expectations regarding its outcomes.
This measure was used to evaluate the feasibility of the CBM-I intervention.
|
After the 1st training session
|
|
Treatment Acceptability Questionnaire (TAQ)
大体时间：2-week follow-up (2 weeks after completion of the 2-week intervention)
|
The TAQ is a 5-item self-report measures that evaluates participants' perceptions of an intervention's acceptability, ethicality, acceptability of side effects, pleasantness and comfort of the intervention.
|
2-week follow-up (2 weeks after completion of the 2-week intervention)
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Mobini S, Mackintosh B, Illingworth J, Gega L, Langdon P, Hoppitt L. Effects of standard and explicit cognitive bias modification and computer-administered cognitive-behaviour therapy on cognitive biases and social anxiety. J Behav Ther Exp Psychiatry. 2014 Jun;45(2):272-9. doi: 10.1016/j.jbtep.2013.12.002. Epub 2013 Dec 31.
- Beard C, Amir N. A multi-session interpretation modification program: changes in interpretation and social anxiety symptoms. Behav Res Ther. 2008 Oct;46(10):1135-41. doi: 10.1016/j.brat.2008.05.012. Epub 2008 Jun 27.
- Beard C. Cognitive bias modification for anxiety: current evidence and future directions. Expert Rev Neurother. 2011 Feb;11(2):299-311. doi: 10.1586/ern.10.194.
- Amir N, Prouvost C, Kuckertz JM. Lack of a benign interpretation bias in social anxiety disorder. Cogn Behav Ther. 2012;41(2):119-29. doi: 10.1080/16506073.2012.662655. Epub 2012 Apr 30.
- Patel TA, Schubert FT, Hom MA, Cougle JR. Correlates of treatment seeking in individuals with social anxiety disorder: Findings from a nationally representative sample. J Anxiety Disord. 2022 Oct;91:102616. doi: 10.1016/j.janxdis.2022.102616. Epub 2022 Aug 6.
- Liu H, Li X, Han B, Liu X. Effects of cognitive bias modification on social anxiety: A meta-analysis. PLoS One. 2017 Apr 6;12(4):e0175107. doi: 10.1371/journal.pone.0175107. eCollection 2017.
- Heinrichs N, Hofmann SG. Information processing in social phobia: a critical review. Clin Psychol Rev. 2001 Jul;21(5):751-70. doi: 10.1016/s0272-7358(00)00067-2.
- Cougle JR, Wilver NL, Day TN, Summers BJ, Okey SA, Carlton CN. Interpretation Bias Modification Versus Progressive Muscle Relaxation for Social Anxiety Disorder: A Web-Based Controlled Trial. Behav Ther. 2020 Jan;51(1):99-112. doi: 10.1016/j.beth.2019.05.009. Epub 2019 May 24.
- Clark DM, McManus F. Information processing in social phobia. Biol Psychiatry. 2002 Jan 1;51(1):92-100. doi: 10.1016/s0006-3223(01)01296-3.
- Amir N, Taylor CT. Interpretation training in individuals with generalized social anxiety disorder: a randomized controlled trial. J Consult Clin Psychol. 2012 Jun;80(3):497-511. doi: 10.1037/a0026928. Epub 2012 Jan 16.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2024年9月26日
初级完成 (实际的)
2025年12月8日
研究完成 (实际的)
2025年12月8日
研究注册日期
首次提交
2026年7月17日
首先提交符合 QC 标准的
2026年8月5日
首次发布 (实际的)
2026年8月7日
研究记录更新
最后更新发布 (实际的)
2026年8月7日
上次提交的符合 QC 标准的更新
2026年8月5日
最后验证
2026年7月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.