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The Parasite and Infestation Study

2026年9月24日 更新者：Julia Sheffield、Vanderbilt University Medical Center

Understanding the Experience of Patient-Physician Diagnostic Incongruency: I Know Something is Wrong But No One Believes Me

Many people have evidence of bugs, parasites, and infestation, but are told by others that they cannot find a cause. This distressing and frustrating experience can last for years, as the person seeks answers. The current study aims to understand the experience of these individuals. In a 1-2 hour session over Zoom, the investigators will ask participants questions about their experience, have them complete self-report questionnaires, and ask them to complete a few games on the computer. The investigators' goal is to help characterize and understand individuals with this experience to aid in better treatment and inform recommendations for providers.

研究概览

地位

招聘中

条件

干预/治疗

详细说明

The current study aims to characterize the experiences of people who have evidence of bugs, parasites, and/or infestation but are told by physicians or other professionals (e.g. vets, pest control) that there is nothing wrong. The investigators seek to understand the emotional and cognitive aspects of this experience, through semi-structured interviews, self-report questionnaires, and cognitive tasks. The study will take a few hours and is conducted remotely, allowing for participation regardless of the participant's physical location. There is practically no aggregate information on this experience, with most current information relying on case reports and medical record review. The investigators hope to provide greater insights into this experience to guide support for individuals going through this difficult process.

研究类型

观察性的

注册 (估计的)

25

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习联系方式

学习地点

  • 美国
    • Tennessee
      • Nashville、Tennessee、美国、37212
        • 招聘中
        • Vanderbilt University Medical Center
        • 接触：

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 至 70年 (成人、年长者)

接受健康志愿者

不

有资格学习的性别

全部

取样方法

非概率样本

研究人群

Adults with a persistent experience of infestation or parasite that physicians or other professionals report no evidence for.

描述

Inclusion Criteria:

  • Men and women aged 18-70 years old
  • At least 50% certain that they have an active infection/infestation/parasite, despite being told by doctor that they do not
  • Ability to read and speak English
  • Access to a computer or phone for virtual visit
  • No self-reported history of schizophrenia-spectrum disorder

Exclusion Criteria:

  • Active substance use disorder (excluding nicotine and caffeine)
  • History of severe head trauma
  • Current use of antipsychotics
  • Serious medical or neurological illness known to interfere with cognitive functioning
  • Diagnosis of a learning disability or cognitive disorder

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

  • 观测模型：COHORT
  • 时间观点：CROSS_SECTIONAL

队列和干预

团体/队列
干预/治疗
PPDI Group
其他：No intervention - observational study

This study will not involve an intervention.

研究衡量的是什么？

主要结果指标

结果测量
措施说明
大体时间
Psychological Wellbeing
大体时间：Baseline

Total score on the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS); scores range from 14-70; higher scores reflect greater wellbeing
Baseline
Social Network
大体时间：Baseline

Ludden Social Network Scale - total score; higher scores reflect larger and closer social network (score: 0-30)
Baseline
Depression
大体时间：Baseline

Total score - Beck Depression Inventory -II; Scores range from 0-63 with higher scores reflecting worse depression
Baseline
Anxiety
大体时间：Baseline

Perseverative Thinking Questionnaire (PTQ); scores range from 0-60, higher scores reflect more perseveration
Baseline
Belief Updating
大体时间：Baseline

Expectations of prior volatility (mu3) calculated from reversal learning task; higher parameter scores reflect greater expectations of volatility
Baseline
BADE
大体时间：Baseline

Evidence Integration Impairment (EII) will be calculated based on decisions on the Bias Against Disconfirmatory Evidence task. Higher scores reflect more difficulty integrating information
Baseline
Interoceptive Awareness
大体时间：Baseline

Multidimensional Assessment of Interoceptive Awareness-2; scores range from 0-185; higher scores reflect better interpersonal awareness
Baseline
Dissociation
大体时间：Baseline

Cernis Felt Sense of Anomaly Scale (CEFSA); scores range from 0-140, higher scores reflect more severe dissociative experiences
Baseline
Childhood Trauma
大体时间：Baseline

Childhood Trauma Questionnaire (CTQ)- scores range from 5-100, higher scores reflect more severe childhood maltreatment
Baseline
DACOBS
大体时间：Baseline

Davos Assessment of Cognitive Biases Scale; higher scores reflect more severe cognitive biases. Scores range from 42-294
Baseline

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

Vanderbilt University Medical Center

调查人员

  • 首席研究员：Julia Sheffield, PhD、Vanderbilt University Medical Center

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2024年12月31日

初级完成 (估计的)

2029年12月1日

研究完成 (估计的)

2030年12月1日

研究注册日期

首次提交

2026年9月18日

首先提交符合 QC 标准的

2026年9月24日

首次发布 (实际的)

2026年9月30日

研究记录更新

最后更新发布 (实际的)

2026年9月30日

上次提交的符合 QC 标准的更新

2026年9月24日

最后验证

2026年9月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • 201489

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)？

未定

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

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