- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00364520
Molecular Epidemiology of Benzene-exposed Workers.
May 19, 2015 updated by: University of Colorado, Denver
Molecular Epidemiology of Benzene-exposed Workers in Shanghai,China
The purpose of this study is to investigate the health effects of benzene exposure in workers in Shanghai, China.
Study Overview
Detailed Description
The purpose of this study is to investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers and to characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
Study Type
Observational
Enrollment (Actual)
2000
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
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Shanghai, China, 200032
- Joint Sino-US Clinical and Molecular Laboratory (JCML)
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 67 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Shanghai Workers
Description
Inclusion Criteria:
Worked for at least one year in a monitored environment Have at least one physical examination recorded
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Exclusion Criteria:
History of cancer, radiation exposure, chemotherapy
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Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Ecologic or Community
- Time Perspectives: Cross-Sectional
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Shanghai Workers
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers.
Time Frame: August 2003 - December 2009
|
Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers
|
August 2003 - December 2009
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
Time Frame: August 2003 - December 2009
|
Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
|
August 2003 - December 2009
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Richard D Irons, PhD, University of Colorado at Denver and Health Sciences Ctr
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
August 1, 2003
Primary Completion (Actual)
December 1, 2009
Study Completion (Actual)
December 1, 2009
Study Registration Dates
First Submitted
August 14, 2006
First Submitted That Met QC Criteria
August 14, 2006
First Posted (Estimate)
August 15, 2006
Study Record Updates
Last Update Posted (Estimate)
May 21, 2015
Last Update Submitted That Met QC Criteria
May 19, 2015
Last Verified
May 1, 2007
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 02-0037
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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