Effects of Marijuana Used on Lung Function in Persons With Chronic Obstructive Pulmonary Disease (COPD)

May 12, 2017 updated by: Rosa Estrada Y Martin, The University of Texas Health Science Center, Houston

Effects of Marijuana Smoking on Pulmonary Function in Patients With COPD

The main hypothesis is that persons that smoke or smoked tobacco and marihuana have worsen lung function as compared with persons that only smoke or smoked tobacco.

Study Overview

Status

Completed

Conditions

Detailed Description

We will follow persons with already diagnosed COPD (chronic bronchitis and/or emphysema). Obtain their smoking history: tobacco and marihuana and review their pulmonary function study results. Then we are planning to compare both groups.

Study Type

Observational

Enrollment (Actual)

200

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Texas
      • Houston, Texas, United States, 77026
        • Lyndon B Johnson General Hospital
      • Houston, Texas, United States, 77030
        • The University of Texas- Health Science Center at Houston

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

25 years to 90 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

COPD patients recruited in pulmonary clinic.

Description

Inclusion Criteria:

  • COPD patients former or current tobacco smokers
  • COPD patients former or current tobacco and marihuana smokers

Exclusion Criteria:

  • History of COPD without pulmonary function testing
  • Refusal to provide smoking or marihuana used history

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
COPD tobacco and/or marihuana users
COPD patients with history of tobacco and/or marihuana smoking.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Obstructive limitation in pulmonary function test
Time Frame: 1 year
Comparison on the severity of obstruction among both groups
1 year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Decreased diffusion capacity for carbon monoxide
Time Frame: 1 year
Comparison on the severity of decreased DLco among groups.
1 year
Airtrapping
Time Frame: 1 year
Comparison on the severity of air-trapping by pulmonary function testing among groups.
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

The University of Texas Health Science Center, Houston

Investigators

  • Principal Investigator: Rosa M Estrada-Y-Martin, MD, The University of Texas Health Science Center, Houston

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

November 1, 2010

Primary Completion (Actual)

December 31, 2016

Study Completion (Actual)

December 31, 2016

Study Registration Dates

First Submitted

March 24, 2010

First Submitted That Met QC Criteria

March 30, 2010

First Posted (Estimate)

March 31, 2010

Study Record Updates

Last Update Posted (Actual)

May 15, 2017

Last Update Submitted That Met QC Criteria

May 12, 2017

Last Verified

May 1, 2017

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • HSC-MS-09-0362

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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