Cognitive Remediation and Functional Skills Training in Schizophrenia

November 16, 2016 updated by: Christopher R. Bowie, National Alliance for Research on Schizophrenia and Depression

Specificity and Generalizability of Cognitive Remediation and Functional Skills Training in Schizophrenia

This randomized trial is examining whether a treatment called cognitive remediation is more effective when it is paired with a social and functional skills training component.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

75

Phase

  • Early Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Canada
    • Ontario
      • Kingston, Ontario, Canada, K7L 3N6
        • Queen's University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Diagnosis of schizophrenia or schizoaffective disorder
  • Enrolled in outpatient mental health care
  • Reading level of 6th grade or higher
  • English speaking

Exclusion Criteria:

  • Medical conditions known to affect cognition

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Cognitive remediation
Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Active Comparator: Functional Adaptive Skills Training
Functional and social skills group treatment
Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills
Active Comparator: Combined Treatment
Combined cognitive remediation and functional adaptive skills training
Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
neurocognition
Time Frame: 12 weeks
12 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
functional competence
Time Frame: 12 weeks
performance-based measures of functional and social competence
12 weeks
neurocognition
Time Frame: 24 weeks
24 weeks
neurocognition
Time Frame: 36 weeks
36 weeks
functional competence
Time Frame: 24 weeks
24 weeks
functional competence
Time Frame: 36 weeks
36 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Alliance for Research on Schizophrenia and Depression

Investigators

  • Principal Investigator: Christopher R Bowie, PhD, Queen's University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

July 1, 2007

Primary Completion (Actual)

August 1, 2010

Study Completion (Actual)

September 1, 2010

Study Registration Dates

First Submitted

August 3, 2010

First Submitted That Met QC Criteria

August 4, 2010

First Posted (Estimate)

August 5, 2010

Study Record Updates

Last Update Posted (Estimate)

November 17, 2016

Last Update Submitted That Met QC Criteria

November 16, 2016

Last Verified

August 1, 2010

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • PSYC-085-08

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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