A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC) (LEGACY)

July 14, 2025 updated by: AbbVie

A Long-Term Non-Interventional Postmarketing Study to Assess Safety and Effectiveness of HUMIRA® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label.

Study Overview

Status

Active, not recruiting

Conditions

Ulcerative Colitis (UC)

Study Type

Observational

Enrollment (Estimated)

8250

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Australia
- Australian Capital Territory
  - Garran, Australian Capital Territory, Australia, 2605
    - The Canberra Hospital /ID# 157980
- New South Wales
  - Camperdown, New South Wales, Australia, 2050
    - Royal Prince Alfred Hospital /ID# 157986
  - Concord, New South Wales, Australia, 2139
    - Concord Repatriation General Hospital /ID# 157983
  - East Lismore, New South Wales, Australia, 2480
    - St Vincent's Hospital /ID# 157978
  - New Lambton, New South Wales, Australia, 2305
    - Hunter New England Local Health District /ID# 157999
- Queensland
  - Herston, Queensland, Australia, 4029
    - Royal Brisbane and Women's Hospital /ID# 158086
  - South Brisbane, Queensland, Australia, 4101
    - Mater Misericordiae Limited /ID# 164171
- South Australia
  - Adelaide, South Australia, Australia, 5000
    - Royal Adelaide Hospital /ID# 158026
  - Bedford, Park, South Australia, Australia, 5042
    - Flinders Medical Centre /ID# 157979
- Victoria
  - Box Hill, Victoria, Australia, 3128
    - Box Hill Hospital /ID# 157987
  - Heidelberg, Victoria, Australia, 3084
    - Austin Health /ID# 157998
  - Melbourne, Victoria, Australia, 3004
    - The Alfred Hospital /ID# 159261
  - Parkville, Victoria, Australia, 3050
    - The Royal Melbourne Hospital /ID# 157993
- Western Australia
  - Murdoch, Western Australia, Australia, 6150
    - Fiona Stanley Hospital /ID# 157992
Austria
- - Innsbruck, Austria, 6020
    - Duplicate_Medizinische Universitat Innsbruck,Universitatsklinik fur Innere Mediz /ID# 120775
  - Salzburg, Austria, 5010
    - Krankenhaus der Barmherzigen Brueder Salzburg /ID# 120776
  - Salzburg, Austria, 5020
    - Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 127897
- Oberoesterreich
  - Linz, Oberoesterreich, Austria, 4010
    - Ordensklinikum Linz GmbH Elisabethinen /ID# 98555
- Wien
  - Vienna, Wien, Austria, 1030
    - Klinik Landstrasse /ID# 121615
Belgium
- - Gent, Belgium, 9000
    - AZ Maria Middelares /ID# 127489
  - Herentals, Belgium, 2200
    - AZ Herentals /ID# 127135
  - Liege, Belgium, 4000
    - CHU de Liege /ID# 127983
  - Liege, Belgium, 4000
    - Groupe Sante CHC - Clinique du MontLegia /ID# 127988
  - Namur, Belgium, 5004
    - Duplicate_Clinical Saint-Luc Bouge /ID# 127987
- Antwerpen
  - Antwerp, Antwerpen, Belgium, 2018
    - Duplicate_ZAS Vincentius /ID# 127398
  - Antwerp, Antwerpen, Belgium, 2020
    - Duplicate_ZAS Middelheim /ID# 129116
  - Bonheiden, Antwerpen, Belgium, 2820
    - Imelda Ziekenhuis /ID# 127497
  - Edegem, Antwerpen, Belgium, 2650
    - Universitair Ziekenhuis Antwerpen /ID# 142757
- Limburg
  - Sint-truiden, Limburg, Belgium, 3800
    - Sint-Trudo Ziekenhuis /ID# 127136
- Oost-Vlaanderen
  - Aalst, Oost-Vlaanderen, Belgium, 9300
    - Onze Lieve Vrouw Hospital /ID# 127986
  - Gent, Oost-Vlaanderen, Belgium, 9000
    - UZ Gent /ID# 127985
  - Gent, Oost-Vlaanderen, Belgium, 9000
    - AZ Sint-Lucas /ID# 127000
  - Sint-Niklaas, Oost-Vlaanderen, Belgium, 9100
    - Vitaz /Id# 141601
- Vlaams-Brabant
  - Leuven, Vlaams-Brabant, Belgium, 3000
    - Universitair Ziekenhuis Leuven /ID# 127984
Canada
- Alberta
  - Edmonton, Alberta, Canada, T5H 4B9
    - GI Research & Associates /ID# 133723
  - Edmonton, Alberta, Canada, T6G 2X8
    - Duplicate_University of Alberta - Zeidler Ledcor Centre /ID# 144673
- British Columbia
  - New Westminster, British Columbia, Canada, V3L 3W5
    - Columbia Gastro Mgmnt Ltd /ID# 128719
  - Surrey, British Columbia, Canada, V3V 1Z1
    - Dr. M. Prest Inc. /ID# 134309
  - Vancouver, British Columbia, Canada, V5Z 3N9
    - Duplicate_University of British Columbia - Eye Care Centre, Vancouver General Ho /ID# 129995
  - Vancouver, British Columbia, Canada, V6Z 2K5
    - Duplicate_(G.I.R.I.) GI Research Institute Foundation /ID# 129095
  - Victoria, British Columbia, Canada, V8V 3M9
    - Percuro Clinical Research, Ltd /ID# 129996
- New Brunswick
  - Fredericton, New Brunswick, Canada, E3B 5N5
    - Dr. Everett Chalmers Reg Hosp. /ID# 135408
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3H 1V7
    - Duplicate_QE II Health Sciences Centre /ID# 128916
- Ontario
  - Brampton, Ontario, Canada, L6S 0C1
    - Bellini Medicine Professional /ID# 145706
  - Guelph, Ontario, Canada, N1H 3R3
    - Guelph GI and Surgery Clinic /ID# 128917
  - Hamilton, Ontario, Canada, L8N 1Y2
    - Charlton Medical Centre /ID# 135390
  - London, Ontario, Canada, N6A 5A5
    - Duplicate_University Hospital - London Health Sciences Centre /ID# 128915
  - Oshawa, Ontario, Canada, L1G 2B9
    - Lakeridge Health - Oshawa /ID# 128275
  - Ottawa, Ontario, Canada, K1H 8L6
    - Ottawa Hospital Research Institute /ID# 128918
  - Ottawa, Ontario, Canada, K1K 0T2
    - Hôpital Montfort /ID# 151588
  - Toronto, Ontario, Canada, M5T 3A9
    - Kensington Screening Clinic /ID# 133720
- Quebec
  - Montreal, Quebec, Canada, H1T 2M4
    - CIUSSS de l'est de l'Ile-de-Montreal - Hopital Maisonneuve-Rosemont /ID# 130321
  - Montréal, Quebec, Canada, H2X 0A9
    - CHUM - Notre-Dame Hospital /ID# 151379
  - Sherbrooke, Quebec, Canada, J1H 5N4
    - CIUSSS de l'Estrie - CHUS /ID# 133031
- Saskatchewan
  - Saskatoon, Saskatchewan, Canada, S7N 0W8
    - Royal University Hospital /ID# 128720
Croatia
- Grad Zagreb
  - Zagreb, Grad Zagreb, Croatia, 10000
    - Clinical Hospital Dubrava /ID# 127982
  - Zagreb, Grad Zagreb, Croatia, 10000
    - General Hospital Sveti Duh /ID# 127977
- Osjecko-baranjska Zupanija
  - Osijek, Osjecko-baranjska Zupanija, Croatia, 31000
    - Duplicate_Klinicki bolnicki centar Osijek /ID# 127980
- Primorsko-goranska Zupanija
  - Rijeka, Primorsko-goranska Zupanija, Croatia, 51000
    - Klinicki bolnicki centar Rijeka /ID# 127979
- Splitsko-dalmatinska Zupanija
  - Split, Splitsko-dalmatinska Zupanija, Croatia, 21000
    - Duplicate_Klinicki bolnicki centar Split /ID# 127978
Denmark
- Hovedstaden
  - Copenhagen Ø, Hovedstaden, Denmark, 2100
    - Rigshospitalet /ID# 98238
  - Herlev, Hovedstaden, Denmark, 2730
    - Herlev Hospital /ID# 98239
  - Hvidovre, Hovedstaden, Denmark, 2650
    - Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 120557
- Nordjylland
  - Aalborg, Nordjylland, Denmark, 9000
    - Aalborg University Hospital /ID# 119215
France
- - Bethune, France, 62408
    - Hospitalier Germon et Gauthier /ID# 137874
  - Lyon, France, 69338
    - Centre des consultations spécialisées de la sauvegarde /ID# 98719
  - Montfermeil, France, 93370
    - GHI Le Raincy - Montfermeil /ID# 98642
  - Paris, France, 75010
    - Duplicate_APHP - Groupe Hospitalier 1 /ID# 98736
  - Paris, France, 75012
    - AP-HP - Hopital Saint-Antoine /ID# 141611
  - Paris, France, 75018
    - AP-HP - Hopital Bichat - Claude-Bernard /ID# 98641
  - Paris, France, 75014
    - Duplicate_AP-HP - Hopital Cochin /ID# 98717
  - Rouen, France, 76000
    - Hôpital Charles-Nicolle /ID# 98721
  - Saint Quentin, France, 02100
    - Cabinet Médical - Dr THEVENIN /ID# 98720
  - Tours, France, 37044
    - Duplicate_Hopital Trousseau /ID# 98716
- Alpes-Maritimes
  - Nice, Alpes-Maritimes, France, 06202
    - Chu de Nice-Hopital L'Archet Ii /Id# 98645
- Auvergne-Rhone-Alpes
  - Clermont, Auvergne-Rhone-Alpes, France, 63100
    - CHU Clermont-Ferrand /ID# 98735
- Bouches-du-Rhone
  - Marseille, Bouches-du-Rhone, France, 13915
    - Duplicate_CHU Hopital Nord /ID# 98639
- Haute-Garonne
  - TOULOUSE Cedex 9, Haute-Garonne, France, 31059
    - CHU Toulouse - Hopital Purpan /ID# 148183
  - Toulouse, Haute-Garonne, France, 31400
    - CHU Toulouse - Hopital Rangueil /ID# 147755
- Herault
  - Montpellier Cedex 5, Herault, France, 34295
    - CHU Montpellier - Hopital Saint Eloi /ID# 217142
- Ile-de-France
  - Clichy, Ile-de-France, France, 92110
    - Hopital Beaujon /ID# 127395
- Isere
  - La Tronche, Isere, France, 38700
    - CHU Grenoble - Hopital Michallon /ID# 98638
- Loire
  - St-Priest-en-Jarez, Loire, France, 42270
    - Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 130978
- Marne
  - Reims CEDEX, Marne, France, 51092
    - CHU Reims - Hôpital Robert Debre /ID# 98640
- Meurthe-et-Moselle
  - Vandoeuvre-les-Nancy, Meurthe-et-Moselle, France, 54500
    - CHRU Nancy - Hopitaux de Brabois /ID# 127394
- Moselle
  - Metz, Moselle, France, 57070
    - Cabinet medical Dr ECUER /ID# 161671
- Nord
  - Lille, Nord, France, 59037
    - CHRU Lille - Hopital Claude Huriez /ID# 98737
- Rhone
  - Lyon, Rhone, France, 69003
    - HCL - Hopital Edouard Herriot /ID# 155711
  - Pierre Benite CEDEX, Rhone, France, 69495
    - HCL - Hopital Lyon Sud /ID# 98718
  - Venissieux, Rhone, France, 69200
    - GH Mutualiste Les Portes Du Sud /ID# 98722
- Somme
  - Amiens CEDEX 1, Somme, France, 80054
    - CHU Amiens-Picardie Site Sud /ID# 98637
Germany
- - Altenburg, Germany, 04600
    - Klinikum Altenburger Land /ID# 131748
  - Bayreuth, Germany, 95444
    - Praxis Dres. Roesler und Lachma /ID# 128466
  - Berlin, Germany, 10117
    - Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 129115
  - Berlin, Germany, 10117
    - Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 129117
  - Berlin, Germany, 12203
    - Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 130318
  - Berlin, Germany, 14050
    - DRK Kliniken Berlin Westend /ID# 98179
  - Berlin, Germany, 10117
    - Duplicate_Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 98124
  - Berlin, Germany, 10318
    - Gastroenterologische Spezialpraxis am Wittenbergplatz /ID# 98117
  - Berlin-Zehlendorf, Germany, 14163
    - Krankenhaus Waldfriede /ID# 98200
  - Bochum, Germany, 44791
    - Klinikum Ruhr Univ Bochum /ID# 148107
  - Braunschweig, Germany, 38126
    - Stadtisches Klinikum Braunschweig /ID# 98123
  - Essen, Germany, 45239
    - Universitaetsmedizin Essen St. Josef Krankenhaus Werden /ID# 98196
  - Garmisch-Partenkirchen, Germany, 82467
    - Klinikum Garmisch-Partenkirchen /ID# 127915
  - Hamburg, Germany, 20099
    - Asklepios Klinik St. Georg /ID# 125216
  - Hamburg, Germany, 20249
    - Forstep /ID# 125206
  - Hamburg, Germany, 20249
    - Magen-Darm-Zentrum /ID# 141610
  - Hamburg, Germany, 20354
    - Gastroenterologie Fontenay /ID# 98195
  - Hamburg, Germany, 22297
    - Israelitisches Krankenhaus Hamburg /ID# 98197
  - Hamburg, Germany, 22559
    - Asklepios Westklinikum Hamburg /ID# 127492
  - Hamburg, Germany, 22587
    - Graefin v.Waldersee&Partner, H /ID# 141607
  - Hamburg, Germany, 22559
    - Duplicate_Gastroenterologie Studien -CED /ID# 98205
  - Iserlohn, Germany, 58644
    - Hoffstadt, Iserlohn, DE /ID# 98208
  - Magdeburg, Germany, 39120
    - Otto-von-Guericke-Universitaet /ID# 129227
  - Muenster, Germany, 48155
    - Medizinisches Versorgungszentrum Portal 10 /ID# 98122
  - Muenster, Germany, 48159
    - Gastro Campus Research GbR /ID# 125558
  - Neumarkt, Germany, 92318
    - Klinikum Neumarkt /ID# 123016
  - Nuremberg, Germany, 90419
    - Klinikum Nuernberg Nord /ID# 134976
  - Regensburg, Germany, 93042
    - Universitaetsklinikum Regensburg /ID# 141606
  - Regensburg, Germany, 93053
    - Praxiszentrum Altemalzerei /ID# 129001
  - Saarbruecken, Germany, 66111
    - Biewer/Mohl, Saarbruecken, DE /ID# 98204
  - Schweinfurt, Germany, 97421
    - Ambulanzzentrum Schweinfurt /ID# 123238
  - Stuhr, Germany, 28816
    - Kardalinos, Stuhr, DE /ID# 98201
  - Weyhe, Germany, 28844
    - Internistische Praxisgemeinschaft /ID# 129000
  - Wiesbaden, Germany, 65185
    - Loehr, Wiesbaden, DE /ID# 98217
- Baden-Wuerttemberg
  - Freiburg, Baden-Wuerttemberg, Germany, 79106
    - Universitaetsklinikum Freiburg /ID# 98176
  - Heidelberg, Baden-Wuerttemberg, Germany, 69120
    - Universitaetsklinik Heidelberg /ID# 98120
  - Heidelberg, Baden-Wuerttemberg, Germany, 69121
    - Praxis Für Gastroent. Dr. Med. Lars Helmstädter, Prof. Dr. Med. Robert Ehehalt /ID# 125211
  - Mannheim, Baden-Wuerttemberg, Germany, 68167
    - Universitatsklinikum Mannheim /ID# 129279
  - Sigmaringen, Baden-Wuerttemberg, Germany, 72488
    - Duplicate_Clinics of Sigmaringen /ID# 98216
  - Ulm, Baden-Wuerttemberg, Germany, 89081
    - Universitaetsklinikum Ulm /ID# 98202
- Bayern
  - Erlangen, Bayern, Germany, 91054
    - Universitaetsklinikum Erlangen /ID# 128179
  - Memmingen, Bayern, Germany, 87700
    - Internistisches Fachzentrum /ID# 123255
  - Muenchen, Bayern, Germany, 81377
    - Duplicate_LMU Klinikum Campus Grosshadern /ID# 98198
  - Munich, Bayern, Germany, 80331
    - Duplicate_Isar Medizin Zentrum /ID# 125213
  - Munich, Bayern, Germany, 80539
    - Duplicate_Gastroenterologie Im Josephinu /ID# 123496
  - Nuremberg, Bayern, Germany, 90409
    - Innere Am Stadtpark /ID# 123015
- Mecklenburg-Vorpommern
  - Rostock, Mecklenburg-Vorpommern, Germany, 18057
    - Universitaetsmedizin Rostock /ID# 128396
  - Schwerin, Mecklenburg-Vorpommern, Germany, 19053
    - Bank, Schwerin, DE /ID# 125215
- Niedersachsen
  - Hannover, Niedersachsen, Germany, 30449
    - Mueller/Mueller-Ziehm, Hanover /ID# 130490
  - Oldenburg, Niedersachsen, Germany, 26123
    - Internistische Praxengemeinschaft Oldenburg /ID# 129120
  - Stade, Niedersachsen, Germany, 21682
    - Gastroenterologische Gemeinschaftspraxis Stade /ID# 98206
- Nordrhein-Westfalen
  - Dortmund, Nordrhein-Westfalen, Germany, 44137
    - Klinikum Dortmund gGmbH /ID# 127061
  - Herne, Nordrhein-Westfalen, Germany, 44623
    - Gastroenterologische Gemeinschaftspraxis Herne /ID# 98121
  - Minden, Nordrhein-Westfalen, Germany, 32423
    - Gastroenterologische Gemeinschaftspraxis Minden /ID# 98115
- Rheinland-Pfalz
  - Koblenz, Rheinland-Pfalz, Germany, 56068
    - Benner & Dommermuth /ID# 129119
  - Ludwigshafen am Rhein, Rheinland-Pfalz, Germany, 67067
    - Duplicate_St. Marien- und Annastiftskrankenhaus /ID# 98235
- Sachsen
  - Leipzig, Sachsen, Germany, 04103
    - Universitaetsklinikum Leipzig /ID# 98116
  - Leipzig, Sachsen, Germany, 04103
    - Eugastro /ID# 98178
  - Leipzig, Sachsen, Germany, 04105
    - Internistische Gemienschaftspraxis fuer Verdauungs- und Stoffwechselerkrankungen /ID# 98119
- Sachsen-Anhalt
  - Halle, Sachsen-Anhalt, Germany, 06108
    - Private Practice - Dr. Thomas Zeisler /ID# 98218
  - Halle (Saale), Sachsen-Anhalt, Germany, 06120
    - Krankenhaus Martha-Maria Halle-Doelau /ID# 122935
- Schleswig-Holstein
  - Kiel, Schleswig-Holstein, Germany, 24146
    - Gastroenterologisch - Hepatologisches MVZ Kiel GmbH /ID# 127798
- Thueringen
  - Jena, Thueringen, Germany, 07747
    - Universitaetsklinikum Jena /ID# 127496
Greece
- - Alexandroupolis, Greece, 68100
    - General University Hospital of Alexandroupolis /ID# 128636
  - Athens, Greece, 10676
    - General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 98756
  - Athens, Greece, 10676
    - General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 98761
  - Heraklion, Greece, 71409
    - Venizeleio General Hospital /ID# 98757
  - Ioannina, Greece, 45500
    - University General Hospital of Ioannina /ID# 127390
  - Thessaloniki, Greece, 54639
    - Theageneio Anticancer Hospital /ID# 141670
  - Thessaloniki, Greece, 54642
    - General Hospital of Thessaloniki Hippokrateio /ID# 127400
- Attiki
  - Amaroussio, Attiki, Greece, 15123
    - Hygeia Hospital /ID# 128637
  - Athens, Attiki, Greece, 11527
    - General Hospital of Athens Ippokratio /ID# 128638
  - Athens, Attiki, Greece, 11527
    - General Hospital of Athens Laiko /ID# 129280
  - Maroussi, Attiki, Greece, 15125
    - Iatriko Kentro Athinon /ID# 98762
Ireland
- - Dublin, Ireland, D09 XR63
    - Beaumont Hospital /ID# 98775
  - Dublin 24, Ireland
    - Duplicate_Adelaide and Meath Hosp,IE /ID# 117947
  - Galway, Ireland, H91 YR71
    - Duplicate_Galway University Hospital /ID# 98763
- Dublin
  - Abbotstown, Dublin, Ireland, D15 X40D
    - Connolly Hospital Blanchardstown /ID# 98895
  - Dublin 7, Dublin, Ireland, D07 R2WY
    - Mater Misericordiae Univ Hospital /ID# 119054
  - Dublin 8, Dublin, Ireland, D08 NHY1
    - St James Hospital /ID# 149406
  - Elm Park, Dublin, Ireland, D04 T6F4
    - St Vincent's University Hospital /ID# 116835
Israel
- - Haifa, Israel, 3109601
    - Rambam Health Care Campus /ID# 129282
  - Kiriat Bialik, Israel, 27000
    - Zavulun Medical Centre /ID# 129048
  - Lower Galilee, Israel, 15208
    - Duplicate_Baruch-Padeh Poriya Medical /ID# 141671
- HaMerkaz
  - Kfar Saba, HaMerkaz, Israel, 4428164
    - Meir Medical Center /ID# 129238
  - Zerifin, HaMerkaz, Israel, 70300
    - Yitzhak Shamir Medical Center /ID# 128996
- Haifa
  - Hadera, Haifa, Israel, 38100
    - Hillel Yaffe Medical Center /ID# 129047
- Tel-Aviv
  - Ramat Gan, Tel-Aviv, Israel, 5265601
    - The Chaim Sheba Medical Center /ID# 129281
- Yerushalayim
  - Jerusalem, Yerushalayim, Israel, 91031
    - Shaare Zedek Medical Center /ID# 126638
  - Jerusalem, Yerushalayim, Israel, 91120
    - Gastroenterology Institute, Division of Medicine /ID# 132530
  - Jerusalem, Yerushalayim, Israel, 931106
    - Clalit Health Services /ID# 129237
Italy
- - Bari, Italy, 70124
    - A.O.U. Consorziale Policlinico di Bari /ID# 144213
  - Brescia, Italy, 25123
    - ASST degli Spedali Civili di Brescia /ID# 137943
  - Brescia, Italy, 25124
    - Duplicate_Fondazione Poliambulanza Istituto Ospedaliero /ID# 141593
  - Catania, Italy, 95126
    - Ospedale Cannizzaro /ID# 138142
  - Como, Italy, 22100
    - Congregazione delle Suore Infermiere dell'Addolorata - Ospedale Valduce /ID# 155712
  - Messina, Italy, 98125
    - Azienda Ospedaliera Universitaria Gaetano Martino /ID# 144212
  - Milan, Italy, 20097
    - Policlinico San Donato /ID# 141383
  - Milan, Italy, 20123
    - Ospedale S Giuseppe /ID# 141395
  - Naples, Italy, 80138
    - Duplicate_Seconda Universita' di Napoli /ID# 141717
  - Novara, Italy, 28100
    - Azienda Ospedaliero Universitaria Maggiore della Carita di Novara /ID# 144084
  - Padova, Italy, 35128
    - Azienda Ospedale-Universita Padova /ID# 137941
  - Palermo, Italy, 90127
    - Duplicate_Azienda Ospedaliera Universitaria Paolo Giaccone /ID# 141397
  - Palermo, Italy, 90146
    - Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello /ID# 141392
  - Varese, Italy, 21100
    - Duplicate_A.O. Circolo e Fondazione Macc /ID# 141394
- Emilia-Romagna
  - Bologna, Emilia-Romagna, Italy, 40138
    - Duplicate_IRCCS AOU di Bologna - Policlinico Sant'Orsola-Malpighi /ID# 137945
- Firenze
  - Florence, Firenze, Italy, 50134
    - Duplicate_Azienda Ospedaliero Universitaria Careggi /ID# 137946
- Foggia
  - San Giovanni Rotondo, Foggia, Italy, 71013
    - Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 137939
- Genova
  - Genoa, Genova, Italy, 16132
    - Ospedale San Martino /ID# 137947
- Lombardia
  - Rozzano, Lombardia, Italy, 20089
    - IRCCS Istituto Clinico Humanitas /ID# 141382
- Milano
  - Milan, Milano, Italy, 20157
    - ASST Fatebenefratelli Sacco /ID# 137944
  - Milan, Milano, Italy, 20157
    - ASST Fatebenefratelli Sacco /ID# 141716
- Napoli
  - Naples, Napoli, Italy, 80131
    - Azienda Ospedaliera Universitaria Federico II /ID# 141381
- Roma
  - Rome, Roma, Italy, 00128
    - Duplicate_Policlinico Universitario Campus Bio-Medico /ID# 141393
  - Rome, Roma, Italy, 00133
    - Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 145912
  - Rome, Roma, Italy, 00149
    - Azienda Ospedaliera San Camillo Forlanini /ID# 144211
  - Rome, Roma, Italy, 00161
    - Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 144080
  - Rome, Roma, Italy, 00168
    - Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 141396
- Torino
  - Turin, Torino, Italy, 10128
    - A.O. Ordine Mauriziano di Torino /ID# 137942
- Verona
  - Negrar, Verona, Italy, 37024
    - IRCCS Ospedale Sacro Cuore Don Calabria /ID# 137940
Mexico
- - Chihuahua, Mexico, 31000
    - Investigacion y Biomedicina de Chihuahua /ID# 150115
  - Metepec, Mexico, 52140
    - Torre de Especialidades Medica /ID# 154276
  - Mexico City, Mexico, 11650
    - Centro Especializado en Diabetes, Obesidad y Prevencion de Enfermedades Cardiova /ID# 138113
  - Mexico City, Mexico, 66465
    - Umsi /Id# 149283
  - Monterrey NL, Mexico, 64623
    - Ruiz Flores, Monterrey, MX /ID# 128379
  - San Luis Potosi, Mexico, 78339
    - Vega Fonseca, San Luis Potosi /ID# 128380
- Guanajuato
  - Leon, Guanajuato, Mexico, 37000
    - Morales Vargas Centro de Investigacion S.C. /ID# 131390
- Hidalgo
  - Pachuca, Hidalgo, Mexico, 42070
    - Asociacion Mexicana para la Investigacion Clinica /ID# 128387
- Jalisco
  - Guadalajara, Jalisco, Mexico, 44570
    - Instituto de Salud Digestiva /ID# 157435
  - Guadalajara, Jalisco, Mexico, 44600
    - Issste /Id# 128386
  - Guadalajara, Jalisco, Mexico, 44650
    - Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 129318
- Morelos
  - Cuernavaca, Morelos, Mexico, 62170
    - Clinica de Higado & Gastroenterologia Integral SC /ID# 128376
- Nuevo Leon
  - Monterrey, Nuevo Leon, Mexico, 64460
    - Hospital Universitario Dr. Jose Eleuterio Gonzalez /ID# 128375
Netherlands
- - Arnhem, Netherlands, 6815 AD
    - Rijnstate /ID# 127397
- Limburg
  - Heerlen, Limburg, Netherlands, 6419 PC
    - Zuyderland Medisch Centrum /ID# 98241
- Noord-Holland
  - Amsterdam, Noord-Holland, Netherlands, 1091 AC
    - Olvg /Id# 98336
- Overijssel
  - Zwolle, Overijssel, Netherlands, 8025 AB
    - Isala /ID# 98317
- Utrecht
  - Amersfoort, Utrecht, Netherlands, 3813 TZ
    - Meander Medisch Centrum /ID# 98338
- Zuid-Holland
  - Leiden, Zuid-Holland, Netherlands, 2333 ZA
    - Leids Universitair Medisch Centrum /ID# 127402
  - Rotterdam, Zuid-Holland, Netherlands, 3045 PM
    - Franciscus Gasthuis & Vlietland, Locatie Gasthuis /ID# 127904
  - Rotterdam, Zuid-Holland, Netherlands, 3015 CE
    - Erasmus Medisch Centrum /ID# 98337
New Zealand
- Canterbury
  - Christchurch, Canterbury, New Zealand, 8011
    - Christchurch Hospital /ID# 164265
Norway
- Akershus
  - Lorenskog, Akershus, Norway, 1478
    - Akershus Universitetssykehus_MAIN /ID# 127159
Puerto Rico
- - Mayaguez, Puerto Rico, 00680-1503
    - Perez Jimenz Gastroenterologo /ID# 110135
  - Ponce, Puerto Rico, 00716
    - Gastro-Hepato & Geriatric Ctr /ID# 113135
  - San Juan, Puerto Rico, 00917-5022
    - Henry A. Rodriguez Ginorio, MD /ID# 113448
  - San Juan, Puerto Rico, 00935
    - School of Medicine University of Puerto Rico-Medical Science Campus /ID# 102067
Spain
- - Alicante, Spain, 03010
    - Hospital General Universitario de Alicante Doctor Balmis /ID# 128467
  - Barcelona, Spain, 08003
    - Hospital Parc de Salut del Mar /ID# 126637
  - Barcelona, Spain, 08906
    - Hospital de Sant Joan Despi Moises Broggi /ID# 128347
  - Caceres, Spain, 10003
    - Hospital San Pedro de Alcantara /ID# 98579
  - Girona, Spain, 17007
    - Hospital Universitario de Girona Doctor Josep Trueta /ID# 130049
  - Huesca, Spain, 22004
    - Duplicate_Hospital San Jorge Huesca /ID# 149628
  - Jaen, Spain, 23007
    - Hospital Universitario de Jaen /ID# 129035
  - Leon, Spain, 24071
    - Hospital de Leon /ID# 131750
  - Madrid, Spain, 28006
    - Hospital Universitario de la Princesa /ID# 98580
  - Madrid, Spain, 28007
    - Hospital General Universitario Gregorio Maranon /ID# 98558
  - Madrid, Spain, 28034
    - Hospital Universitario Ramon y Cajal /ID# 98596
  - Madrid, Spain, 28041
    - Hospital Universitario 12 de Octubre /ID# 98575
  - Madrid, Spain, 28046
    - Hospital Universitario La Paz /ID# 98582
  - Madrid, Spain, 28040
    - Hospital Clinico San Carlos /ID# 98577
  - Malaga, Spain, 29010
    - Hospital Universitario Virgen de la Victoria /ID# 129038
  - Pontevedra, Spain, 36071
    - Complejo Hospitalario Universitario de Pontevedra /ID# 128354
  - Salamanca, Spain, 37711
    - Hospital Universitario de Salamanca /ID# 98589
  - Segovia, Spain, 40002
    - Hospital General de Segovia /ID# 148926
  - Sevilla, Spain, 41009
    - Hospital Universitario Virgen Macarena /ID# 128346
  - Sevilla, Spain, 41013
    - Hospital Universitario Virgen del Rocio /ID# 98557
  - Sevilla, Spain, 41014
    - Hospital Universitario Virgen de Valme /ID# 129036
  - Tarragona, Spain, 43005
    - Hospital Universitari Joan Xxiii De Tarragona /ID# 129122
  - Toledo, Spain, 45071
    - Hospital Virgen de la Salud /ID# 98595
  - Valencia, Spain, 46010
    - Hospital Clinico Universitario de Valencia /ID# 131749
  - Valencia, Spain, 46026
    - Hospital Universitario y Politecnico La Fe /ID# 98597
  - Valencia, Spain, 46014
    - Consorci Hospital General Universitario de Valencia /ID# 98616
  - Valladolid, Spain, 47012
    - Hospital Rio Hortega /ID# 98590
  - Zaragoza, Spain, 50009
    - Hospital Clinico Universitario Lozano Blesa /ID# 98556
  - Zaragoza, Spain, 50009
    - Hospital Universitario Miguel Servet /ID# 131188
  - Zaragoza, Spain, 50015
    - Hospital Royo Villanova /ID# 149850
- A Coruna
  - A Coruña, A Coruna, Spain, 15006
    - Complejo Hospitalario Universitario A Coruña /ID# 129002
  - Ferrol, A Coruna, Spain, 15405
    - Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 129124
  - Santiago de Compostela, A Coruna, Spain, 15706
    - Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 98619
- Alicante
  - Elche, Alicante, Spain, 03203
    - Hospital General Universitario de Elche /ID# 129121
  - San Juan de Alicante, Alicante, Spain, 03550
    - Hospital Universitario San Juan de Alicante /ID# 130167
- Asturias
  - Gijon, Asturias, Spain, 33394
    - Hospital Universitario de Cabuenes /ID# 141998
  - Oviedo, Asturias, Spain, 33011
    - Hospital Universitario Central de Asturias /ID# 98617
- Balears
  - Manacor, Balears, Spain, 07500
    - Hospital de Manacor /ID# 128348
- Barcelona
  - Badalona, Barcelona, Spain, 08916
    - Hospital Universitario Germans Trias i Pujol /ID# 98592
  - Esplugues de Llobregat, Barcelona, Spain, 08950
    - Hospital Sant Joan de Deu /ID# 151342
  - Esplugues de Llobregat, Barcelona, Spain, 08950
    - Hospital Sant Joan de Deu /ID# 155774
  - L'Hospitalet de Llobregat, Barcelona, Spain, 08907
    - Hospital Universitari de Bellvitge /ID# 98584
  - Sabadell, Barcelona, Spain, 08208
    - Consorci Corporacio Sanitaria Parc Tauli Sabadell /ID# 98585
  - Viladecans, Barcelona, Spain, 08840
    - Hospital de Viladecans /ID# 155500
- Cadiz
  - Jerez de la Frontera, Cadiz, Spain, 11407
    - Duplicate_Hospital Universitario de Jerez de la Frontera /ID# 128345
- Cantabria
  - Santander, Cantabria, Spain, 39008
    - Hospital Universitario Marques de Valdecilla /ID# 98581
- Castellon
  - Castellon de la Plana, Castellon, Spain, 12004
    - Hospital General de Castellon /ID# 128351
- Ciudad Real
  - Alcazar de San Juan, Ciudad Real, Spain, 13600
    - Hospital General La Mancha Centro /ID# 98588
- Cordoba
  - Córdoba, Cordoba, Spain, 14004
    - Hospital Universitario Reina Sofia /ID# 98586
- Granada
  - Motril, Granada, Spain, 18600
    - Hospital Comarcal Santa Ana de Motril /ID# 129040
- Illes Balears
  - Palma de Mallorca, Illes Balears, Spain, 07120
    - Hospital Universitari Son Espases /ID# 148214
- Jaen
  - Andujar, Jaen, Spain, 23740
    - Hospital Alto Guadalquivir /ID# 129006
- Las Palmas
  - Las Palmas de Gran Canaria, Las Palmas, Spain, 35019
    - Hospital Universitario Dr. Negrin /ID# 98578
- Madrid
  - Alcala de Henares, Madrid, Spain, 28805
    - Hospital Universitario Principe de Asturias /ID# 131751
  - Alcorcon, Madrid, Spain, 28922
    - Hospital Universitario Fundacion Alcorcon /ID# 98576
  - Fuenlabrada, Madrid, Spain, 28942
    - Hospital Universitario de Fuenlabrada /ID# 98591
  - Mostoles, Madrid, Spain, 28935
    - Hospital General de Mostoles /ID# 130319
  - Parla, Madrid, Spain, 28981
    - Hospital Universitario Infanta Cristina /ID# 98635
  - San Sebastián de Los Reyes, Madrid, Spain, 28702
    - Hospital Infanta Sofia /ID# 98615
- Malaga
  - Antequera, Malaga, Spain, 29200
    - Hospital de Antequera /ID# 129041
- Murcia
  - Cartagena, Murcia, Spain, 30202
    - Hospital General Universitario Santa Lucia /ID# 129125
- Ourense
  - Orense, Ourense, Spain, 32005
    - Complejo Hospitalario Universitario Ourense /ID# 128349
- Pontevedra
  - Vigo, Pontevedra, Spain, 36204
    - Hospital Xeral Cies (CHUVI) /ID# 129515
  - Vigo, Pontevedra, Spain, 36213
    - Hospital Meixoeiro (CHUVI) /ID# 128355
- Santa Cruz De Tenerife
  - San Cristóbal de La Laguna, Santa Cruz De Tenerife, Spain, 38320
    - Hospital Universitario Canarias /ID# 129037
- Valencia
  - Sagunto, Valencia, Spain, 46520
    - Hospital de Sagunto /ID# 98587
- Vizcaya
  - Barakaldo, Vizcaya, Spain, 48902
    - Hospital San Eloy /ID# 147830
  - Bilbao, Vizcaya, Spain, 48013
    - Hospital Universitario Basurto /ID# 129123
  - Galdakao, Vizcaya, Spain, 48960
    - Hospital Universitario de Galdakao /ID# 98618
Sweden
- Stockholms Lan
  - Solna, Stockholms Lan, Sweden, 171 64
    - Karolinska University Hospital Solna /ID# 171247
  - Stockholm, Stockholms Lan, Sweden, 112 18
    - Capio St Gorans Sjukhus /ID# 126123
  - Stockholm, Stockholms Lan, Sweden, 182 88
    - Danderyd Hospital /ID# 98897
  - Stockholm, Stockholms Lan, Sweden, 118 83
    - Sodersjukhuset /ID# 124158
- Uppsala Lan
  - Uppsala, Uppsala Lan, Sweden, 75185
    - Uppsala University Hospital /ID# 120558
- Vastra Gotalands Lan
  - Gothenburg, Vastra Gotalands Lan, Sweden, 413 45
    - Duplicate_Sahlgrenska University Hospital /ID# 141672
  - Skovde, Vastra Gotalands Lan, Sweden, 541 85
    - Skaraborgs Sjukhus Skovde /ID# 98898
United Kingdom
- - Blackpool, United Kingdom, FY3 8NR
    - Blackpool Teaching Hospitals NHS Foundation Trust /ID# 164213
  - Cambridge, United Kingdom, CB2 0QQ
    - Duplicate_Cambridge University Hospitals NHS Foundation Trust /ID# 145704
  - Dudley, United Kingdom, DY1 2HQ
    - The Dudley Group NHS Foundation Trust /ID# 164119
  - Fontana, United Kingdom, 92335
    - Kaiser Perm Riverside Med Ctr /ID# 146043
  - Harrow, United Kingdom, HA1 3UJ
    - London North West University Healthcare NHS Trust /ID# 145953
  - ISLE OF Wight, United Kingdom, PO30 5GT
    - Isle of Wight NHS Trust /ID# 168166
  - London, United Kingdom, SE5 9RS
    - King's College Hospital NHS Foundation Trust /ID# 145698
  - Manchester, United Kingdom, M9 2AA
    - Manchester University NHS Foundation Trust /ID# 145702
  - Stockport, United Kingdom, SK2 7JE
    - Stockport NHS foundation trust /ID# 144090
  - Wolverhampton, United Kingdom, WV10 0QP
    - The Royal Wolverhampton NHS Trust /ID# 164209
  - Wolverhampton, United Kingdom, WV10 0QP
    - The Royal Wolverhampton NHS Trust /ID# 98901
  - Yeovil, United Kingdom, BA21 4AT
    - Yeovil Hospital - Somerset NHS Foundation Trust) /ID# 146042
- Cheshire West And Chester
  - Warrington, Cheshire West And Chester, United Kingdom, WA5 1QG
    - Warrington and Halton Hospitals NHS Foundation Trust /ID# 144089
- County Durham
  - Darlington, County Durham, United Kingdom, DL3 6HX
    - County Durham and Darlington NHS Foundation Trust /ID# 145914
- Devon
  - Plymouth, Devon, United Kingdom, PL6 8DH
    - Derriford Hospital and the Royal Eye Infirmary /ID# 157432
- Dorset
  - Poole, Dorset, United Kingdom, BH15 2JB
    - University Hospitals Dorset NHS Foundation Trust /ID# 164108
- East Riding Of Yorkshire
  - Hull, East Riding Of Yorkshire, United Kingdom, HU3 2JZ
    - Hull University Teaching Hospitals NHS Trust /ID# 98899
- England
  - London, England, United Kingdom, W12 0HS
    - Hammersmith Hospital /ID# 145916
- Essex
  - Basingstoke, Essex, United Kingdom, RG24 9NA
    - Hampshire Hospitals NHS Foundation Trust /ID# 98900
- Glasgow City
  - Glasgow, Glasgow City, United Kingdom, G12 0YN
    - Gartnavel General Hospital /ID# 153818
- Greater London
  - London, Greater London, United Kingdom, E1 2ES
    - Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 145703
- Hampshire
  - Southampton, Hampshire, United Kingdom, SO16 6YD
    - University Hospital Southampton NHS Foundation Trust /ID# 145676
- Norfolk
  - Great Yarmouth, Norfolk, United Kingdom, NR31 6LA
    - James Paget University Hospitals NHS Foundation Trust /ID# 164106
  - Kings Lynn, Norfolk, United Kingdom, PE30 4ET
    - The Queen Elizabeth Hospital, Kings Lynn NHS Foundation Trust /ID# 145937
- Nottinghamshire
  - Nottingham, Nottinghamshire, United Kingdom, NG5 1PB
    - Nottingham City Hospital /ID# 145678
- Suffolk
  - Bury St Edmunds, Suffolk, United Kingdom, IP33 2QZ
    - West Suffolk Hospital /ID# 164105
- Surrey
  - Kingston upon Thames, Surrey, United Kingdom, KT2 7QB
    - Kingston Hospital NHS Foundation Trust /ID# 164109
- Warwickshire
  - Coventry, Warwickshire, United Kingdom, CV2 2DX
    - UH Coventry & Warwickshire /ID# 145680
- West Yorkshire
  - Leeds, West Yorkshire, United Kingdom, LS9 7TF
    - Leeds Teaching Hospitals NHS Trust /ID# 157949
United States
- Alabama
  - Birmingham, Alabama, United States, 35209
    - Birmingham Gastroenterology Associates P.C /ID# 102063
  - Birmingham, Alabama, United States, 35233
    - University of Alabama at Birmingham - Main /ID# 131646
  - Huntsville, Alabama, United States, 35801
    - Longwood Research /ID# 118662
  - Mobile, Alabama, United States, 36617
    - Mobile Medical & Diagnostic Center, AL /ID# 102064
  - Mobile, Alabama, United States, 36606
    - East View Medical Research, LLC /ID# 116259
- Arizona
  - Phoenix, Arizona, United States, 85018
    - HOPE Research Institute /ID# 127947
  - Tucson, Arizona, United States, 85724
    - University Of Arizona /ID# 117836
  - Tucson, Arizona, United States, 85719-1478
    - Duplicate_University of Arizona Cancer Center - North Campus /ID# 140387
- Arkansas
  - North Little Rock, Arkansas, United States, 72117
    - Arkansas Gastroenterology /ID# 113898
- California
  - Coronado, California, United States, 92118-1408
    - Southern California Res. Ctr. /ID# 116898
  - La Jolla, California, United States, 92093
    - Moores Cancer Center at UC San Diego /ID# 133722
  - La Mirada, California, United States, 90638
    - McGuire, Jr. La Mirada, CA /ID# 116257
  - Los Alamitos, California, United States, 90720
    - Atay, Los Alamitos, CA /ID# 110175
  - Murrieta, California, United States, 92562
    - Temecula Valley Endoscopy Ctr /ID# 118660
  - Orange, California, United States, 92868
    - Community Clinical Trials, CA /ID# 117335
  - San Carlos, California, United States, 94070
    - Digestive Care Medical Center /ID# 122075
  - San Diego, California, United States, 92114-3643
    - Precision Research Institute - San Diego /ID# 103638
  - San Diego, California, United States, 92114-3643
    - Precision Research Institute - San Diego /ID# 113445
  - Santa Monica, California, United States, 90404
    - Santa Monica Research Institut /ID# 118675
  - Yorba Linda, California, United States, 92886
    - Duplicate_St. Joseph Heritage Group - Yorba Linda /ID# 133721
- Colorado
  - Wheat Ridge, Colorado, United States, 80033-2896
    - Duplicate_Western States Clinical Research, Inc. /ID# 116237
- Connecticut
  - Bridgeport, Connecticut, United States, 06606
    - Gastro Assoc of Fair County /ID# 113443
  - Hamden, Connecticut, United States, 06518
    - Gastroenterology Center of Connecticut /ID# 102057
  - Middletown, Connecticut, United States, 06457
    - Middlesex Hospital /ID# 122077
  - New Haven, Connecticut, United States, 06510
    - Yale Univ Digestive Diseases /ID# 141987
- District of Columbia
  - Washington, District of Columbia, United States, 20007
    - Georgetown University Hospital /ID# 113437
- Florida
  - Brandon, Florida, United States, 33510-3107
    - Brandon Premier Health Care, PA/Gulf Coast Research Group, LLC /ID# 148230
  - Gainesville, Florida, United States, 32607
    - Sarkis Clinical Trials /ID# 137948
  - Hollywood, Florida, United States, 33021-6545
    - Hollywood Research Center /Id# 214723
  - Maitland, Florida, United States, 32751-6108
    - Ctr for Advanced Gastroenterol /ID# 116236
  - Miami, Florida, United States, 33144
    - Paradise Clnical Research, LLC /ID# 212027
  - Miami, Florida, United States, 33134
    - Research Associates of South Florida,LLC /ID# 148212
  - Miami, Florida, United States, 33165
    - Duplicate_Abel & Buchheim, P.R., Inc. /ID# 143863
  - Naples, Florida, United States, 34102
    - Gastroenterology Group Naples /ID# 105837
  - New Port Richey, Florida, United States, 34653
    - Advanced Research Institute, Inc /ID# 211335
  - Orange Park, Florida, United States, 32073
    - Duplicate_North Florida Gastro Research /ID# 128538
  - Orlando, Florida, United States, 32803
    - Advent Health /ID# 145705
  - Orlando, Florida, United States, 32803
    - Endoscopic Research, Inc. /ID# 136883
  - Orlando, Florida, United States, 32807
    - Duplicate_Combined Research Orlando - Phase I-IV /ID# 141660
  - Panama City, Florida, United States, 32405
    - Digestive Diseases Center /ID# 118116
  - Parkland, Florida, United States, 33076
    - Palekar. Parkland, FL /ID# 108202
  - Plantation, Florida, United States, 33322
    - BRCR Medical Center Inc /ID# 152015
  - Port Orange, Florida, United States, 32127
    - Advanced Medical Research Center /ID# 116235
  - Sunrise, Florida, United States, 33351-7311
    - Precision Clinical Research /ID# 127849
  - Tallahassee, Florida, United States, 32308
    - Digestive Disease Clinic /ID# 107162
  - Tampa, Florida, United States, 33614-2700
    - Guardian Angels Health Center /ID# 209706
  - Tampa, Florida, United States, 33613
    - University of South Florida- Neuroscience Institute /ID# 213305
  - Wellington, Florida, United States, 33414
    - South Florida Ctr Gastro, P.A. /ID# 166784
  - Winter Park, Florida, United States, 32789
    - Shafran Gastroenterology Ctr /ID# 117839
- Georgia
  - Atlanta, Georgia, United States, 30342
    - Atlanta Gastro Assoc /ID# 107164
  - Atlanta, Georgia, United States, 30322
    - Winship Cancer Institute of Emory University /ID# 133724
  - Macon, Georgia, United States, 31201
    - Gastroenterology Associates of Central Georgia, LLC /ID# 117838
  - Suwanee, Georgia, United States, 30024
    - Atlanta Gastroenterology Spec /ID# 103619
- Idaho
  - Idaho Falls, Idaho, United States, 83404
    - Grand Teton Research Group /ID# 108197
- Illinois
  - Arlington Heights, Illinois, United States, 60005
    - Northwest Gastro, S.C. /ID# 103620
  - Arlington Heights, Illinois, United States, 60005
    - Northwest Gastro, S.C. /ID# 145707
  - Champaign, Illinois, United States, 61820
    - Christie Clinic, LLC /ID# 116258
  - Chicago, Illinois, United States, 60611-2927
    - Northwestern University Feinberg School of Medicine /ID# 126760
  - Chicago, Illinois, United States, 60612
    - Rush University Medical Center /ID# 132979
  - Chicago, Illinois, United States, 60637-1443
    - The University of Chicago Medical Center /ID# 114115
  - Evanston, Illinois, United States, 60201
    - Duplicate_NorthShore University HealthSystem /ID# 107165
  - Oak Lawn, Illinois, United States, 60453
    - DM Clinical Research/Southwest /ID# 120635
  - Park Ridge, Illinois, United States, 60068
    - Duplicate_North Suburban Gastro Assoc /ID# 134437
  - Urbana, Illinois, United States, 61801
    - Carle Foundation Hospital Digestive Health Research Center /ID# 117417
- Iowa
  - Clive, Iowa, United States, 50325
    - Iowa Digestive Disease Center - Clive /ID# 107159
  - Iowa City, Iowa, United States, 52242
    - University of Iowa Hospitals and Clinics /ID# 134432
- Kansas
  - Kansas City, Kansas, United States, 66160-8500
    - University of Kansas Health Sy /ID# 134436
  - Kansas City, Kansas, United States, 66160
    - Univ Kansas Med Ctr /ID# 120917
  - Wichita, Kansas, United States, 67226
    - Kansas Gasteroenterology /ID# 214827
- Louisiana
  - Houma, Louisiana, United States, 70360
    - Houma Digestive Health Special /ID# 125711
  - Lafayette, Louisiana, United States, 70506
    - Gastro Clinic of Acadiana, LA /ID# 119155
  - Shreveport, Louisiana, United States, 71105-6800
    - Louisiana Research Center, LLC /ID# 102055
- Maryland
  - Annapolis, Maryland, United States, 21401
    - Investigative Clinical Research /ID# 102056
  - Baltimore, Maryland, United States, 21201
    - University of Maryland, Baltimore /ID# 116897
  - Chevy Chase, Maryland, United States, 20815
    - Duplicate_MGG Group Co, Inc.Chevy Chase Clinical Research /ID# 107157
  - Columbia, Maryland, United States, 21045
    - Gastro Center of Maryland /ID# 126969
  - Towson, Maryland, United States, 21204
    - Endoscopic Microsurgery Assoc /ID# 102065
- Massachusetts
  - Attleboro, Massachusetts, United States, 02703
    - Attleboro Gastroenterology, PC /ID# 113899
  - Brockton, Massachusetts, United States, 02302
    - Commonwealth Clinical Studies /ID# 118597
- Michigan
  - Ann Arbor, Michigan, United States, 48109
    - University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 105836
  - Ann Arbor, Michigan, United States, 48197
    - Huron Gastroenterology Assoc /ID# 132484
  - Detroit, Michigan, United States, 48202
    - Henry Ford Hospital /ID# 103617
  - Farmington Hills, Michigan, United States, 48334
    - Detroit Clinical Research Center /ID# 123235
- Minnesota
  - Rochester, Minnesota, United States, 55905-0001
    - Mayo Clinic - Rochester /ID# 116899
- Mississippi
  - Jackson, Mississippi, United States, 39216-4643
    - Univ of Mississippi Med Ctr,US /ID# 132981
- Missouri
  - Saint Louis, Missouri, United States, 63104
    - St. Louis University /ID# 163794
  - Saint Louis, Missouri, United States, 63110
    - Washington University-School of Medicine /ID# 107156
- Nebraska
  - Omaha, Nebraska, United States, 68124
    - CHI Health Research Center /ID# 116255
- New Jersey
  - Mount Laurel, New Jersey, United States, 08057
    - Cooper Digestive Health Instit /ID# 103615
  - Vineland, New Jersey, United States, 08360
    - Duplicate_The Gastro Group of S. Jersey /ID# 129902
  - Voorhees, New Jersey, United States, 08043
    - Allied Gastrointestinal Associates /ID# 107158
- New York
  - Lake Success, New York, United States, 11042
    - NYU Langone Long Island Clinical Research Associates /ID# 107163
  - Lynbrook, New York, United States, 11563
    - Orlin & Cohen /ID# 117895
  - Mineola, New York, United States, 11501
    - Progressive Gastroenterology Consultants /ID# 105835
  - New Hyde Park, New York, United States, 11040
    - Digestive Disease Care /ID# 133489
  - New Hyde Park, New York, United States, 11040
    - North Shore University Hospital /ID# 127948
  - New Windsor, New York, United States, 12553
    - Duplicate_Premier Medical Group /ID# 140388
  - New York, New York, United States, 10029
    - The Mount Sinai Hospital /ID# 108201
  - New York, New York, United States, 10065
    - Weill Cornell Medical College /ID# 135052
  - New York, New York, United States, 10279
    - Manhattan Clinical Research, LLC /ID# 113442
  - New York, New York, United States, 10024
    - New York Gastroenterology Associates - Upper West Side /ID# 133689
  - Poughkeepsie, New York, United States, 12601
    - Premier Medical Group - GI Division /ID# 140384
  - Rochester, New York, United States, 14618-5703
    - Gastoenterology Group of Rochester /ID# 113438
  - Rochester, New York, United States, 14642
    - University of Rochester Medical Center /ID# 126152
  - Williamsville, New York, United States, 14221
    - Ctr Digest, Allergic & Imm Dis /ID# 125502
- North Carolina
  - Asheville, North Carolina, United States, 28801
    - Asheville Gastro Assoc /ID# 144367
  - Cary, North Carolina, United States, 27518
    - Cary Gastroenterology Assoc PA /ID# 108198
  - Chapel Hill, North Carolina, United States, 27514-4220
    - Univ NC Chapel Hill /ID# 102059
  - Charlotte, North Carolina, United States, 28203
    - Atrium Health Carolinas Medical Center /ID# 126970
  - Charlotte, North Carolina, United States, 28207
    - Charlotte Gastroenterology and Hepatology, PLLC /ID# 102058
  - Charlotte, North Carolina, United States, 28211
    - Carolina Digestive Health Associates /ID# 108199
  - Charlotte, North Carolina, United States, 28215
    - Carolinas Research center /ID# 211288
  - Greenville, North Carolina, United States, 27834
    - Atlantic Gastroenterology, PA /ID# 135536
  - Greenville, North Carolina, United States, 27834
    - Carolina Research /ID# 134133
  - Rocky Mount, North Carolina, United States, 27804
    - Boice-Willis Clinic, P.A. /ID# 103618
  - Wilmington, North Carolina, United States, 28401
    - Trial Management Associates /ID# 138459
  - Winston-Salem, North Carolina, United States, 27157
    - Atrium Health Wake Forest Baptist Medical Center /ID# 113436
- Ohio
  - Cleveland, Ohio, United States, 44195
    - Cleveland Clinic Main Campus /ID# 108055
  - Middleburg Heights, Ohio, United States, 44130
    - Duplicate_Clinical Research Solutions /ID# 207698
  - Sylvania, Ohio, United States, 43560-2767
    - ProMedica Physicians Digestive Healthcare /ID# 156529
  - Warren, Ohio, United States, 44484
    - Avamar Center for Endoscopy /ID# 113440
  - Youngstown, Ohio, United States, 44514
    - Southwoods Surgical Hospital /ID# 133038
- Oregon
  - Portland, Oregon, United States, 97210
    - Northwest Gastroenterology Clinic /ID# 116896
- Pennsylvania
  - Hershey, Pennsylvania, United States, 17033
    - Penn State University and Milton S. Hershey Medical Center /ID# 133688
  - Malvern, Pennsylvania, United States, 19355
    - Main Line Gastro Assoc /ID# 113446
  - Philadelphia, Pennsylvania, United States, 19129
    - Drexel University /ID# 126968
  - Philadelphia, Pennsylvania, United States, 19148
    - Methodist Hospital /ID# 129461
  - Philadelphia, Pennsylvania, United States, 19140
    - Duplicate_Temple University Hospital /ID# 108203
  - Sayre, Pennsylvania, United States, 18840
    - Guthrie Medical Group, PC /ID# 105838
- Rhode Island
  - Cranston, Rhode Island, United States, 02920
    - Duplicate_Bierwirth, Cranston, RI /ID# 113435
- South Carolina
  - Charleston, South Carolina, United States, 29425
    - Medical University of South Carolina /ID# 113439
  - Columbia, South Carolina, United States, 29203-8902
    - Consultants in Gastroenterology - Columbia NE /ID# 126517
  - Greenville, South Carolina, United States, 29615
    - Greenville Endoscopy Center /ID# 129900
  - West Columbia, South Carolina, United States, 29169-3612
    - Biocentric Healthcare Research /ID# 213980
- South Dakota
  - Rapid City, South Dakota, United States, 57701
    - Rapid City Medical Center - GI Research /ID# 201191
  - Sioux Falls, South Dakota, United States, 57108
    - Singaram Gastroenterology /ID# 113447
- Tennessee
  - Chattanooga, Tennessee, United States, 37403
    - Erlanger Institute for Clinical Research /ID# 126151
  - Franklin, Tennessee, United States, 37067
    - Duplicate_Franklin Endoscopy Center /ID# 113444
  - Jackson, Tennessee, United States, 38305
    - Clinical Research Solutions /ID# 154153
  - Murfreesboro, Tennessee, United States, 37130
    - Mid-State Gastroenterology /ID# 125457
- Texas
  - Houston, Texas, United States, 77030
    - University of Texas MD Anderson Cancer Center /ID# 144198
  - Houston, Texas, United States, 77036
    - Precision Research Institute, LLC /ID# 211340
  - Houston, Texas, United States, 77090
    - Houston Digestive Dis Clinic /ID# 102076
  - Houston, Texas, United States, 77030
    - Baylor College of Medicine /ID# 103636
  - Houston, Texas, United States, 77030
    - Duplicate_Kelsey-Seybold Clinic /ID# 125942
  - Houston, Texas, United States, 77450
    - Houston Endoscopy And Research Center - Katy Freeway /ID# 206978
  - McAllen, Texas, United States, 78503
    - Rio Grande Gastroenterology /ID# 210218
  - Pasadena, Texas, United States, 77505
    - Digestive Health Center /ID# 113897
  - Plano, Texas, United States, 75093
    - Digestive Health Assoc of TX /ID# 116215
  - San Antonio, Texas, United States, 78229
    - Gastroenterology Clinic of San /ID# 113441
  - San Antonio, Texas, United States, 78229
    - San Antonio Gastro Assoc /ID# 143435
  - Temple, Texas, United States, 76508-0001
    - Baylor Scott & White Medical Center- Temple /ID# 103639
  - Tyler, Texas, United States, 75701
    - Digestive Health Spec of Tyler /ID# 138144
- Utah
  - Ogden, Utah, United States, 84403
    - Care Access - Ogden /ID# 213432
  - West Valley City, Utah, United States, 84120
    - Granger Medical Clinic /ID# 122896
- Vermont
  - Burlington, Vermont, United States, 05401-1473
    - University of Vermont Medical Center /ID# 102075
- Virginia
  - Chesapeake, Virginia, United States, 23320
    - Gastro Assoc of Tidewater /ID# 102061
  - Fairfax, Virginia, United States, 22031
    - Gastro Assoc. of N. Va. /ID# 125495
  - Leesburg, Virginia, United States, 20176
    - Emeritas Research Group, LLC /ID# 135537
  - Norfolk, Virginia, United States, 23502
    - Digestive and Liver Disease Sp /ID# 125943
  - Virginia Beach, Virginia, United States, 23454
    - Gastroenterology Ltd. /ID# 103640
- Washington
  - Seattle, Washington, United States, 98109
    - University of Washington /ID# 122076
  - Wenatchee, Washington, United States, 98801
    - Confluence Health /ID# 118661
- West Virginia
  - Morgantown, West Virginia, United States, 26505
    - Duplicate_Morgantown Surgical Associates /ID# 123082
- Wisconsin
  - Madison, Wisconsin, United States, 53715
    - St. Mary's Hospital /ID# 116915
  - Madison, Wisconsin, United States, 53792-0001
    - Univ of Wisconsin Hosp/Clinics /ID# 103637
  - Milwaukee, Wisconsin, United States, 53226-3522
    - Froedtert Memorial Lutheran Hospital /ID# 102066
  - Milwaukee, Wisconsin, United States, 53215
    - Wisconsin Center for Advanced Research /ID# 103616
  - Monroe, Wisconsin, United States, 53566
    - Reach /Id# 116256

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 99 years (Adult, Older Adult)

Accepts Healthy Volunteers

Sampling Method

Probability Sample

Study Population

Adult patients with moderately to severely active Ulcerative Colitis (UC) who have been prescribed HUMIRA according to the local label and adult patients being prescribed and treated with IMM (6-mercaptopurine or azathioprine) with no concurrent biologic use.

Description

Inclusion Criteria:

For enrollment into the HUMIRA treatment group; adult patients with moderately to severely active UC who has been prescribed HUMIRA therapy according to routine clinical practice and meets one of the following:
1. Is currently taking HUMIRA therapy and has received at least 8 weeks of therapy; OR
2. Is entering after participation in an Abbott or AbbVie sponsored UC study and; has received continuous HUMIRA therapy since initiation of therapy
For enrollment into the IMM treatment group; adult patients with moderately to severely active UC who has been prescribed IMM therapy, is currently taking IMM therapy, and has received at least 12 consecutive weeks of IMM therapy
Patients capable of and willing to grant authorization for use/disclosure of data being collected and provided to AbbVie prior to any registry-related data being collected, and to comply with the requirements of the Registry protocol

Exclusion Criteria:

Patients on IMM therapy without a concurrent biologic if they cannot continue to be treated with IMM therapy or
Patients who are being treated with any investigational agents and/or approved biologics other than Humira.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort
Immunomodulatory Therapy Patients who are being prescribed and treated with Immunomodulatory Therapy
Adalimumab (Humira) Treatment Patients who are prescribed and treated with Adalimumab

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Evaluation of long term safety of Adalimumab in patients with moderately to severely active UC Time Frame: 10 years observational period	10 years observational period

Secondary Outcome Measures

Outcome Measure	Time Frame
Evaluation of long term effectiveness of Adalimumab in patients with moderately to severely active UC who have had an inadequate response to conventional therapy Time Frame: 10 years observational period	10 years observational period

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

AbbVie

Investigators

Study Director: ABBVIE INC., AbbVie

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Related Info

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 29, 2013

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 1, 2028

Study Registration Dates

First Submitted

May 3, 2013

First Submitted That Met QC Criteria

May 3, 2013

First Posted (Estimated)

May 7, 2013

Study Record Updates

Last Update Posted (Actual)

July 16, 2025

Last Update Submitted That Met QC Criteria

July 14, 2025

Last Verified

July 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

P11-282

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product

product manufactured in and exported from the U.S.

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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Study Overview

Status

Conditions

Study Type

Enrollment (Estimated)

Contacts and Locations

Study Locations

Participation Criteria

Eligibility Criteria

Ages Eligible for Study

Accepts Healthy Volunteers

Sampling Method

Study Population

Description

Study Plan

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort

What is the study measuring?

Primary Outcome Measures

Outcome Measure

Time Frame

Secondary Outcome Measures

Outcome Measure

Time Frame

Collaborators and Investigators

Sponsor

Investigators

Publications and helpful links

Helpful Links

Study record dates

Study Major Dates

Study Start (Actual)

Primary Completion (Estimated)

Study Completion (Estimated)

Study Registration Dates

First Submitted

First Submitted That Met QC Criteria

First Posted (Estimated)

Study Record Updates

Last Update Posted (Actual)

Last Update Submitted That Met QC Criteria

Last Verified

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Studies a U.S. FDA-regulated device product

product manufactured in and exported from the U.S.

Clinical Trials on Ulcerative Colitis (UC)

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